Osteogenesis Imperfecta
What is Osteogenesis Imperfecta?
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Osteogenesis imperfecta (OI) is a genetic disorder in which bones break easily. Sometimes the bones break for no known reason. OI can also cause weak muscles, brittle teeth, a curved spine and hearing loss. The cause is a gene defect that affects how you make collagen, a protein that helps make bones strong. Usually you inherit the faulty gene from a parent. Sometimes, it is due to a mutation, a random gene change.
OI can range from mild to severe and symptoms vary from person to person. A person may have just a few or as many as several hundred fractures in a lifetime. There is no cure, but you can manage symptoms. Treatments include exercise, pain medicine, physical therapy, wheelchairs, braces and surgery.
National Institute of Arthritis and Musculoskeletal and Skin Diseases
Related Osteogenesis Imperfecta Images and Links
Osteogenesis imperfecta - PubMed Health - National Center for ... Causes, incidence, and risk factors. Osteogenesis imperfecta (OI) is a congenital disease, meaning it is present at birth. It is frequently caused by ... Read MoreOsteogenesis Imperfecta: MedlinePlus Osteogenesis imperfecta (OI) is a genetic disorder in which bones break easily. Sometimes the bones break for no known reason. OI can also cause weak muscles, brittle ... Read More
Osteogenesis Imperfecta – NIH Osteoporosis and Related Bone ... Resources for patients and medical professionals on osteogenesis imperfecta and how it affects other diseases from NIH Osteoporosis and Related Bone Diseases National ... Read More
Osteogenesis imperfecta - Genetics Home Reference Osteogenesis imperfecta (OI) is a group of genetic disorders that mainly affect the bones. The term "osteogenesis imperfecta" means imperfect bone formation. Read More
Osteogenesis Imperfecta - GeneReviews - NCBI Bookshelf Disease characteristics. Osteogenesis imperfecta (OI) is a group of disorders characterized by fractures with minimal or absent trauma, dentinogenesis imperfecta (DI ... Read More
Osteogenesis imperfecta: MedlinePlus Medical Encyclopedia Osteogenesis imperfecta is a condition causing extremely fragile bones. Causes Osteogenesis imperfecta (OI) is a congenital disease, meaning it is present ... Read More
Osteogenesis imperfecta - NIH Office of Rare Diseases Research (ORDR) A US Department of Health and Human Service project providing information on genetic and rare diseases. A comprehensive body of resources on Osteogenesis imperfecta Read More
Osteogenesis Imperfecta This booklet is not copyrighted and is in the public domain. Formal permission to copy and distribute this material is not required. For more copies, contact the ... Read More
What is Osteogenesis Imperfecta? - Arthritis, Musculoskeletal and ... This is a public information piece. Osteogenesis imperfecta (OI) is a disease that causes weak bones that break easily. It is known as brittle bone disease. Read More
Osteogenesis imperfecta A US Department of Health and Human Service project providing information on genetic and rare diseases. A comprehensive body of resources on Osteogenesis imperfecta Read More
