Asthenia

INFLUENZA (FLUMIST) Side Effects Report # 337347
INFLUENZA (FLUMIST) side effect was reported on 01/14/2009. Female patient, child 6.0 years of age, was vaccinated with INFLUENZA (FLUMIST). After vaccination, patient experienced the following side effects: aphonia, asthenia, asthenia, barium swallow, blood albumin normal"SHE RECEIVED THE FLU SHOT IN MID-OCTOBER AND DISPLAYED A FEVER DURING VETERAN'S DAY WEEKEND WITH NO OTHER SYMPTOMS. SHE FELL OFF THE MONKEY BARS AT SCHOOL ON NOV 13 AND STARTED TO COMPLAIN OF TINGLING AND LOSS OF 'CONTROL' OF LIMBS ON RIGHT SIDE ON NOV 14. SHE STARTED LOSING HER VOICE NOV 30. SHE COMPLAINED OF HER HEAD TINGLING ON DEC 9 AND SUBSEQUENTLY WENT TO DOCTOR ON DEC 10 AND HAS HAD MRI'S, NERVE CONDUCTION TESTS, ETC AND WAS FINALLY DIAGNOSED WITH GBS ON/ABOUT DEC 12. 1/16/09-records received for DOS 12/10-12/13/08-DC DX: Guillain-Barre syndrome. Presented with C/O tingling all four extremities for about 4 weeks, back pain and leg pain. Day prior to hospitalization fell from monkey bar approximately 6 feet high. Subsequently C/O tingling in all 4 extremities. Seen by chiropractor. Few days later lost voice, whispery and hypophonic. DX: sciatica and recommended bedrest for 1 month. PE: reflexes absent ankle and knee jerk bilaerally.12/29/08-follow-up visit with neurology, after 12/25/08 developed left facial palsy and at time of visit nearly resolved. Voice remains with whisper and occasionally chokes on liquids. Jerky gait. Mild weaknesses throughout. 1/9/09-admitted with multiple cranial nerve palsy. Began IVIG. Discharged 1/13/09.". NONENONE"NERVE CONDUCTION, MRI, BARIUM SWALLOW TEST, 1/16/09-records received-CSF: protein 77, glucose 52.NCV abnormal, F-wave. MRI normal. Nerve conduction studies and electromyelography:general acquired sensorimotor polyneuropathy, mixed. CBC, BM" . Patient was hospitalized Patient recovered.


INFLUENZA (FLUMIST) Side Effects Report # 337473
INFLUENZA (FLUMIST) side effect was reported on 01/15/2009. Male patient, child 6.0 years of age, was vaccinated with INFLUENZA (FLUMIST). After vaccination, patient experienced the following side effects: abnormal behaviour, activities of daily living impaired, affect lability, angiogram, arteriovenous malformation"Acute icshemic stroke (basilar artery thrombus). Underwent mechanical thrombectomy 11/25/08. 2/2/09 Received ER medical records of 11/19/2008. FINAL DX: acute non-specific HA Records reveal patient experienced worsening HA x 5 days w/cloudy vision left eye, fatigue, irritability & nausea. Had been seen by PCP 2 days prior & dx w/left otitis media. Tx w/oral antibiotics. Exam in ER was WNL & tx w/IVF & IV meds. Improved & d/c to home. 2/3/09 Received PCP office records of 11/17/08-1/18/2009. FINAL DX: left OM w/viral URI Records reveal patient experienced left eye vision deficit, decreased hearing left ear, left side headache, decreased appetite & energy. Tx w/oral antibiotics & would refer to Ophtho if s/s persisted. RTC 11/21 s/p ER visit w/URI & OM resolving. RTC 11/22 w/persistent but intermittent HA & had missed school. OM had resolved but tx w/oral antibiotics. Referred for MRI. RTC 1/12/09 s/p recent hospitalization for acute ischemic stroke with basilar artery thrombus occlusion s/p mechanical thrombectomy on 11/25/08 & having vomiting. Sent for urgent MRI. RTC 1/15/09 for conference. 2/09/09 Received hospital medical records of 11/24-12/3/2008. FINAL DX: acute ischemic stroke, basilar artery thrombus occlusion w/resultant bilateral posterior circulation strokes; s/p mechanical thrombectomy 11/25/08. D/C Summary mixed in with records which reveal patient had been transferred to PICU from outlying ER. Patient experienced retroorbital eye pain & HA x 10 days prior to admit. One week prior to admit had trouble catching ball from left side. Five days prior to admit had severe HA behind left eye. One day prior to admit had dizziness, vomiting, peripheral vision loss but no pain. On day of admit, had generalized pain, abnormal behavior, talking nonsense, incomplete sentences. Deficits at d/c included: right arm dysmetria w/minimal weakness, LLE dysmetria, quandrantanopia, dysarthria & left side sensory deficit, required assist to walk due to incoordination. D/C to inpatient re". PMH: URI s/s x 1 mo. Recurrent OM & ear tube insertion."LABS: WBC 20.9, ANC 17.8(H), lymphs 10.3%(l). Creatinine 0.3(L), ALK 150(L), AST 58(H). CT brain abnormal. Protein C 0.72(L), protein S antigen, free 54(L). CT angiogram abnormal & c/w acute left PCA distribution ischemic infarct. Echoc" . Patient was hospitalized Patient recovered.

INFLUENZA (FLUMIST) Side Effects Report # 338704
INFLUENZA (FLUMIST) side effect was reported on 01/30/2009. Male patient, 14.0 years of age, was vaccinated with INFLUENZA (FLUMIST). After vaccination, patient experienced the following side effects: asthenia, convulsion, electrocardiogram, musculoskeletal stiffness, pallorHE HAD CONVULSIONS FOR A DURATION OF ABOUT 20 SECONDS; HE DOESN'T REMEMBER ANY OF THAT TIME; HE WAS EXTREMELY PALE; THIS WAS ABOUT 15 MINUTES AFTER THE SHOT WAS ADMINISTERED AND HE HAD LEFT THE DR OFFICE AND WAS IN THE TRUCK WITH HIS FATHER LEAVING WHEN THE CONVULSIONS STARTED AND HIS DAD TURNED AROUND AND DROVE HIM BACK TO THE OFFICE WHERE HE LAID DOWN FOR ABOUT 30 MINUTES UNTIL HIS COLOR RETURNED. THE OFFICE INDICATED THEY FEEL HE JUST FAINTED. PATIENT'S DAD WITNESSED THE TIGHTENING UP OF THE ENIRE BODY AND THE FLAILING AROUND OF HIS HEAD AND ARMS. BY THE TIME THE OFFICE WAS INVOLVED PATIENT HAD COME OUT OF THAT PORTION AND WAS JUST PALE AND WEAK.. NONE - WELL CHECK PHYSICALALLERGY TO SUPRAX; NO OTHER HEALTH ISSUESMONITORED BLOOD PRESSURE AND EKG . During the same period patient was treated with NONE. Patient recovered.

INFLUENZA (FLUMIST) Side Effects Report # 341418
INFLUENZA (FLUMIST) side effect was reported on 03/04/2009. Female patient, child 8.0 years of age, was vaccinated with INFLUENZA (FLUMIST). After vaccination, patient experienced the following side effects: asthenia, blood albumin increased, blood alkaline phosphatase increased, blood creatine phosphokinase normal, blood magnesium increased"Bilateral weakness in legs and urinary difficulty, starting 2 weeks after vaccinations. Patient was hospitalized, supportive care, symptoms self-resolved. 4/20/09 MR received for DOS 2/13-16/2009 with D/C DX: Acute infective polyneuritis. Pt presented several times to PCP with c/o bilateral leg pain and weakness with difficulty urinating. PE (+) for decreased strength in legs, shotty nodes and tenderness to palpation below the knees. DTRs intact. Concern for GBS. Referred to ER. Admitted to R/o GBS/Myositis. Pt developed neck pain 2 days s/p vax then progressed as above. F/U 2/18/09. Now able to walk on own, no urinary difficulties but still with some pain in feet.". upper respiratory infection. URI at time of vaccinationsNone PMH: none.ESR 72 mm/hr. Labs and Diagnostics: UA WNL. UC (-). CK 70. CRP 0.16. Alk Phos 240. Total protein 9.0. Albumin 5.2. CBC with WBC 12.5. ESR initially 72 then down to 16. Phosphate 5.4 (H). Mg++ 2.1 (H). X-ray lower extremities WNL. . During the same period patient was treated with None. Patient was hospitalized Patient recovered.

INFLUENZA (FLUMIST) Side Effects Report # 342125
INFLUENZA (FLUMIST) side effect was reported on 03/13/2009. Female patient, child 12.0 years of age, was vaccinated with INFLUENZA (FLUMIST). After vaccination, patient experienced the following side effects: arthralgia, asthenia, myalgia, , "Information has been received from a consumer concerning her daughter a 13 year old female who in October 2008, was vaccinated with a third dose of GARDASIL. There was no concomitant medication. In December 2008, the patient experienced muscle pain, weakness and joint pain and weakness and the symptoms persisted since to present. The patient did not sought medical attention. Additional information has been requested.". NoneNone . During the same period patient was treated with None. Patient recovered.