Muscular weakness

INFLUENZA (FLUMIST) Side Effects Report # 341418
INFLUENZA (FLUMIST) side effect was reported on 03/04/2009. Female patient, child 8.0 years of age, was vaccinated with INFLUENZA (FLUMIST). After vaccination, patient experienced the following side effects: asthenia, blood albumin increased, blood alkaline phosphatase increased, blood creatine phosphokinase normal, blood magnesium increased"Bilateral weakness in legs and urinary difficulty, starting 2 weeks after vaccinations. Patient was hospitalized, supportive care, symptoms self-resolved. 4/20/09 MR received for DOS 2/13-16/2009 with D/C DX: Acute infective polyneuritis. Pt presented several times to PCP with c/o bilateral leg pain and weakness with difficulty urinating. PE (+) for decreased strength in legs, shotty nodes and tenderness to palpation below the knees. DTRs intact. Concern for GBS. Referred to ER. Admitted to R/o GBS/Myositis. Pt developed neck pain 2 days s/p vax then progressed as above. F/U 2/18/09. Now able to walk on own, no urinary difficulties but still with some pain in feet.". upper respiratory infection. URI at time of vaccinationsNone PMH: none.ESR 72 mm/hr. Labs and Diagnostics: UA WNL. UC (-). CK 70. CRP 0.16. Alk Phos 240. Total protein 9.0. Albumin 5.2. CBC with WBC 12.5. ESR initially 72 then down to 16. Phosphate 5.4 (H). Mg++ 2.1 (H). X-ray lower extremities WNL. . During the same period patient was treated with None. Patient was hospitalized Patient recovered.


INFLUENZA (FLUMIST) Side Effects Report # 341934
INFLUENZA (FLUMIST) side effect was reported on 03/17/2009. Male patient, 24.0 years of age, was vaccinated with INFLUENZA (FLUMIST). After vaccination, patient experienced the following side effects: alpha 2 globulin increased, ataxia, beta globulin normal, blood albumin normal, blood creatine phosphokinase increasedService member was a basic trainee and received multiple vaccines at the end of September 2008 and then developed lower extremity weakness and paresthesias in late October-early November 2008 time-frame. First noted tingling in bilateral great toes which then progressed to calves and thighs. SM was admitted in November 2008 and treated with steroids. He was then discharged to Inpatient Rehab x 8 days with ongoing lower extremity weakness and ataxia. He currently is experiencing ongoing lower extremity weakness and paresthesias. He is pending a medical board. Diagnosed as ADEM. 4/2/09-records received for DOS 11/8-11/17/08- DC DX:Acute transverse myelitis versus ADEM. Ataxia secondary to 1st diagnosis. urinary retention resolving. Received immunizations 3 weeks prior and had 1 week of progressive muscle weakness with mostly lower limb involvement and urinary retention. Began with tingling sensation of big toes progressing to legs buckling and no longer able to walk.Transferred to rehabiliation.. None"NKDA, no history of chronic conditions""06 Nov 2008, SERUM, Creatine Kinase, 565 (H*) IU/L; 08 Nov 2008, SERUM, Protein Electrophoresis; Albumin, 4.20 g/dL; Alpha-1-Globulin, .40 (H) g/dL; Alpha-2-Globulin, 0.98 (H) g/dL; Beta-Globulin, 0.94 g/dL; Gamma-Globulin 1.28 g/dL; Albumi" . During the same period patient was treated with None. Patient was hospitalized Patient recovered.