Asthenia

INFLUENZA (FLUVIRIN) Side Effects Report # 341902
INFLUENZA (FLUVIRIN) side effect was reported . NA patient was vaccinated with INFLUENZA (FLUVIRIN). After vaccination, patient experienced the following side effects: asthenia, dizziness, nausea, throat tightness, "Weakness, Dizziness, Mild Nausea - 20 Mins after injection - feeling (mild) of throat closing VP (Briefly)". NoneNone Except new onset HTNNone needed . Patient recovered.


INFLUENZA (FLUVIRIN) Side Effects Report # 342846
INFLUENZA (FLUVIRIN) side effect was reported on 03/27/2009. Male patient, 58.0 years of age, was vaccinated with INFLUENZA (FLUVIRIN). After vaccination, patient experienced the following side effects: abasia, asthenia, back pain, barium swallow abnormal, blood chloride decreased"DURING LATTER PART OF FEBRUARY PATIENT REPORTED TO LOCAL EMERGENCY ROOM WITH COMPLAINT OF WEAKNESS AND LEG PAIN. WAS TOLD HE HAD A MUSCLE STRAIN GIVEN ANTI-INFLAMMATORY (IBUPROFEN) AND SENT HOME. RETURNED A SECOND TIME SOME DAYS LATER UNABLE TO WALK AND IN EXTREME PAIN. THE EMERGENCY ROOM PHYSICIAN AT THAT TIME WITH THE HELP OF NEUROLOGY SPECIALIST AT CLINIC GAVE THE DIAGNOSIS OF GUILLAIN BARRE SYNDROME. PATIENT WAS SUBSEQUENTLY TRANSPORTED TO THE HOSPITAL WHERE HE WAS STABILIZED AND THEN SENT TO THE REHABILITATION SECTION OF THIS HOSPITAL. THE PATIENT IS CURRENTLY (03/27/2009) IN THIS FACILITY. 4/15/09 received hospital medical records of 3/8-3/24/2009. FINAL DX: acute Guillain-Barre syndrome; UTI; stage 2 coccyx decubitus ulcer; hyponatremia, resolved; neuropathic bladder; deconditioning. Records reveal patient experienced progressive LE weakness, left facial droop; UE weakness; urinary retention. Had been out of country 1/09 & had cold, fever, cough, nasal congestion. Approx 2/28/09 began to feel unwell, developed pain in legs & back. Seen in ER & dx w/muscle sprain. No improvement w/meds & in fact developed weakness of LEs requiring walker use. Saw PCP & noted to have UTI & tx w/antibiotics. Progressive weakness continued until pt unable to get OOB & developed left facial droop. Seen again in ER & transferred to higher level of care. Neuro & Uro consults done. LP done. Tx w/IVIG x 5 days. Feeding tube placed. Gradually improved & transferred to inpatient rehab.". NONE"NONE TO MY KNOWLEDGE PMH: back pain, depression, s/p vasectomy, diverticulosis, proctitis, cataracts, dysuria. Allergy: codeine, HA & flushing. Family hx: CVA, DM, cancer.""Guillain Barre LABS: ESR 13, CRP 0.76. Sodium 129, chloride 96(L), creatinine 0.5(L). Liver enzymes WNL. CSF: glucose 65(N), protein 380(H), segs 16(H), c/s neg. CBC: hematocrit 37.4(L), lymphs 10%(L), monos 13%(H), segs 74%(H), eos" . During the same period patient was treated with "03/05/2009 lEVAQUIN 750, IBUPROFEN 800 02/27/2009 MIRAPEX, FLUTICASONE 2/27/09 DIAZEPAM 02/10/2009 DIAZEPAM". Patient was hospitalized Patient recovered.

INFLUENZA (FLUVIRIN) Side Effects Report # 342851
INFLUENZA (FLUVIRIN) side effect was reported on 03/27/2009. Male patient, 64.0 years of age, was vaccinated with INFLUENZA (FLUVIRIN). After vaccination, patient experienced the following side effects: asthenia, balance disorder, blood culture negative, blood product transfusion, blood sodium decreased"64HM h/o DM, HTN, HLD, BPH p/w weakness that started yesterday midmorning. He first felt weak during work, when he noticed that he could not keep a good grip on his handtools; he had trouble squeezing the trigger on the nailgun and using his screwdriver. The weakness was equal on both sides. Morning of admission, the patient was feeling even more weak, and he fell once in his house because of weakness in his legs, R>L. He has had a lot of problems walking and keeping his balance. There have been no changes to his medication regimen. He has not had any previous episodes of this type of weakness. He says the weakness is equal on both sides. He has not had any blurry vision or double vision. Denies slurred speech, drooping or drooling out of one side of his face, problems swallowing/choking, or confusion/disorientation. He recently got his flu shot 10/16 (about one month prior to presentation). He also had a stomach infection last weekend (seven days prior to presentation) where he had a lot of liquid diarrhea, especially on the day of onset of that illness. He also had nausea and vomiting that weekend, and was unable to keep any food down until Monday. Since Monday, there was complete resolution of his symptoms. He did not try any new foods; he did not eat any old/expired canned foods; no one around him is sick. No recent travels outside the Metroplex. Patiet was felt to have an acute inflammatory demyelinating polyneuropathy (Guillain Barre Syndrome) and was treated with IVIG. Patient is currently in a skilled nursing unit, has a motorized wheelchair. 4/8/09 Received hospital medical records of 11/13-12/1/2008. FINAL DX: Guillian Barre syndrome; SIADH resolved; hypotension resolved. Records reveal patient experienced nausea/vomiting/diarrhea following flu shot & developed progressive distal to proximal weakness. LP done & found to have high protein. Admitted to ICU. Tx w/IVIG x 5 days. Improved slowly & transferred to SNF for inpatient rehab. 4/21/09 Rec". none"diabetes, hypertension, hyperlipidemia, degenerative joint disease PMH: BPH.""LABS: CBC WNL. Sodium 127(L). CSF: protein 130 (H), glucose 78(H), WBC 33(H), lymphs 26%, neutros 73%, RBC 2380(H). EMG/NCS abnormal. Blood, CSF, urine c/s neg, although tx for presumed UTI." . During the same period patient was treated with "rosuvastatin, cyclobenzaprine, naproxen, doxazosin, finasteride". Patient was hospitalized Patient recovered.

INFLUENZA (FLUVIRIN) Side Effects Report # 344932
INFLUENZA (FLUVIRIN) side effect was reported on 04/27/2009. Male patient, 40.0 years of age, was vaccinated with INFLUENZA (FLUVIRIN). After vaccination, patient experienced the following side effects: acute disseminated encephalomyelitis, asthenia, csf protein normal, csf white blood cell count negative, demyelination"After I received the flu shot I developed sever numbness on my extremities witihn 2-3 weeks. After that I developed severe weakness, loss of motor power mostly on the right hand and leg, tachycardia, sever muscle twitches, contracture on right lower extremity, difficulty breathing because of tachycardia. I was diagnosed as Acute dissemintaed encephalomyelitis (ADEM) and my Brain MRI showed diffuse demyelinization of the brain. I recovered mostly. I report this after I finished my follow up with neurology departmnts to make sure it is not a presentation of MS. I received 2 courses of steroids meanwhile that was not helpful. I still have numbness on my right leg and foot and muscle twitches. 5/28/09 Medical records received DOS 3/11/08 to 2/2/09. FINAL DIAGNOSIS: Acute disseminated encephalomyelitis, cervical stenosis. Post vaccination presented with numbness of hands feet face. Generalized weakness and fatigue. Shortness of breath, tachycardia, PVCs. Multifocal muscle twitching. 6/8/09 Hospital record (Multiple Sclerosis Center) received DOS 4/1/09. FINAL DIAGNOSIS: Acute disseminated encephalomyelitis, cervical stenosis. Follow up exam received. No new codes other than patient reports uveitis treated with prednisone eye drops in June 2008 and pericarditis treated with ibuprofen in July 2008.\ksk". "Hyperlipidemia , GERD""Medical records received DOS 3/11/08 to 2/2/09. Orchidectomy for undescended testicle. 6/8/09 Hospital record (Multiple Sclerosis Center) received DOS 4/1/09. Uveitis, Mycarditis."Lumbar puncture 2 times within 9 months interval was negative for possible MS panel. Four more Brain MRIs were negative for new lesions. EMG and NCV were Normal. Visual evoked potential was normal. Lumbar puncture did not show any elevated . During the same period patient was treated with "omeprazole , Simvastatin. 5/28/09 Medical records received DOS 3/11/08 to 2/2/09. omeprazole, simvastin, clonazepam, acetaminophen, corticosteroids. Medical records received DOS 3/11/08 to 2/2/09. Prenisone eye drops, ibuprofen.". Patient recovered.

INFLUENZA (FLUVIRIN) Side Effects Report # 350464
INFLUENZA (FLUVIRIN) side effect was reported on 06/24/2009. Male patient, 33.0 years of age, was vaccinated with INFLUENZA (FLUVIRIN). After vaccination, patient experienced the following side effects: alanine aminotransferase increased, arthralgia, aspartate aminotransferase increased, asthenia, blood albumin normal"Pt. developed onset of paresthesias (tingling) in B/L hands, neck stiffness, occas. hand numbness, hip pain, & feeling flushed on eve of 11/17/08. Flu shot given 11/4/08. NV on 11/18/08 -> referred to PCP. Eval. at ER 11/28/08 -> D/C with script for anxiolytic. Increasing ext pain -> ER 11/29/08 -> inpt. x8 days for daily plasmaphoresis. 7/1/09 Hospital records received DOS 11/30/09 to 12/07/08. Assessment: Guillain-Barre syndrome. Patient presented with tingling of hands and fingers, followed by flu-like symptoms with myalgias and arthralgias in several muscles and joints. Could barely ambulate and unable to work. Decreased muscle strength upper and lower extremities. Gait is wide-based, slow, and unsteady. Daily plasmaphoresis.". None known"None known or specified . PMH: back pain, right tibia / fibula fracture requiring ORIF.""LABS and DIAGNOSTICS: NCS - abnormal. Total CPK is 91. Alkaline Phosphatase is 97, SGOT 128, SGPT 301, Total Bilirubin is 0.4, albumin 4, globulin 3.8, BUN 16, creatinine 0.8. Hematocrit is 45, WBC 10400, platelet count 316000. CSF glucose" . During the same period patient was treated with None at time of vaccination -> currently on METOPROLOL.. Patient was hospitalized Patient recovered.