Hypoaesthesia

INFLUENZA (FLUVIRIN) Side Effects Report # 336555
INFLUENZA (FLUVIRIN) side effect was reported on 12/31/2008. Female patient, 64.0 years of age, was vaccinated with INFLUENZA (FLUVIRIN). After vaccination, patient experienced the following side effects: angioedema, blister, dyspnoea, hypoaesthesia, pain"Approximately 1 wk following injection: large hives 4" to 6" (blister like) on both legs from knee to hip for about 1 week- shooting pains in hands-followed by numbness in fingers- now in finger tips and pain in Achilles tendons (still hurts but not so acute) still injured and shortness of breath.". NonePenicillin . Patient recovered.


INFLUENZA (FLUVIRIN) Side Effects Report # 340370
INFLUENZA (FLUVIRIN) side effect was reported . Female patient, 65.0 years of age, was vaccinated with INFLUENZA (FLUVIRIN). After vaccination, patient experienced the following side effects: dyspnoea, electromyogram abnormal, eye pain, eye pain, headache"Acute onset of excruciating right shoulder and upper arm pain following flu virus immunization. Pain intensity very high (9+/10) and maximal at onset. Pain is sharp and throbbing and constant since injection. Deep aching and muscle weakness and atrophy in upper right arm. Also, sharp/shooting pain affecting eyes and head. Numbness and muscle weakness continuing chronic right upper arm and shoulder pain, significant muscle weakness continuing with physicians for diagnostic work up. 4/3/09-records received-office visit 1/21/09-C/O 3 months of right upper arm lateral aspect being painful with decreased strength. 4/16/09 neurology consult received for DOS 12/16/08-C/O headaches with black spots in front of eyes. Anxiety worsenes tension type headaches. Impression: chronic daily headaches both migraine and tension type and analgesic rebound headache. Daytime somnolence snoring and gasping respiration and weight gain. Lancinating headaches. 2/2/09-C/O right upper arm pain since receiving flu shot.". No illness"Arrhythmia, migraines, hypothyroidism, hypertension, degenerative dise disease. 4/3/09-records received-PMH:HTN, arrhythmia with PVCs, hypothyroidism, HRT, GERD, chronic low back pain with sciatica, osteoarthritis. 4/16/09-records received-PMH migraine headaches and daily headaches for 20 years.""Neuropathy, abnormal EMG and nerve conduction study 2/09/2009. Physical therapy, blood labs, (CBC), (ANA) ordered. 4/3/09-records received-EMG and nerve conduction study abnormal evidence of minimal right sided median neuropathy loss of se" . During the same period patient was treated with "NORVASC, NEXIUM, TOPROL, SYNTHROID, BENICAR, ALDACTONE, PREMARIN". Patient recovered.

INFLUENZA (FLUVIRIN) Side Effects Report # 342795
INFLUENZA (FLUVIRIN) side effect was reported on 03/16/2009. Male patient, 66.0 years of age, was vaccinated with INFLUENZA (FLUVIRIN). After vaccination, patient experienced the following side effects: abdominal pain, areflexia, arthralgia, atrial fibrillation, autonomic nervous system imbalance"12/2/08 S&S inc. numbness/tingling in hands/feet. 12/3/08 ER for intense pain in joints = Dilaudid. 12/5/08 medical center = constipation/MAALOX. 12/7/08 numbness/tingling hands/feet & muscle control problems & pt fell x2 & went to clinic & transferred to hospital & currently still in rehab since 12/12/08. 5/22/09 Hospital records received DOS 12/7/08 - 12/12/08. FINAL DIAGNOSIS: Guillain-Barre syndrome, urinary retention, Paroxysmal atrial fibrillation, autonomic instability, partial CN IV palsy. Post Vaccination: abdominal pain, multiple joint pain, progressive extremity weakness resulting in multiple falls. Tingling sensation palms. Hands became weak, cold intolerance, constipation, bloody diarrhea. Course lung sounds, diminished lung sounds. Diminished sensation extremities. Loss of reflexes lower extremities. Withdrew foot on right with upgoing toes. Poor hand finger coordination. Diplopia IVIG administered. Episodes of hypertension and hypotension.". No"Flat Feet 5/22/09 Hospital records received DOS 12/7/08 - 12/12/08. melanoma, seborrheic dermatitis, pneumonia, infected wrist, arthroscopic knee surgeries, umbilical hernia repair, fusion of left hallux.""MRI and Lumbar puncture on 12/7/08 at hospital. Medical center-Lyme titre, Influenza testing 5/22/09 Hospital records received DOS 12/7/08 - 12/12/08. LABS and DIAGNOSTICS: CHEM - Sodium 134 (L) Potassium 3.2 (L) Chloride 97 (L) Glucose" . During the same period patient was treated with "Aspirin 81mg's daily 5/22/09 Hospital records received DOS 12/7/08 - 12/12/08. ibuprofen, omeprazole, Dilaudid, milk of magnesia, Colace, aspirin, vitamins, fish oil, hydralazine, Flomax, acetominophen, Bisacodyl Rectal, Enoxaparin, Gabape". Patient was hospitalized Patient recovered.

INFLUENZA (FLUVIRIN) Side Effects Report # 344932
INFLUENZA (FLUVIRIN) side effect was reported on 04/27/2009. Male patient, 40.0 years of age, was vaccinated with INFLUENZA (FLUVIRIN). After vaccination, patient experienced the following side effects: acute disseminated encephalomyelitis, asthenia, csf protein normal, csf white blood cell count negative, demyelination"After I received the flu shot I developed sever numbness on my extremities witihn 2-3 weeks. After that I developed severe weakness, loss of motor power mostly on the right hand and leg, tachycardia, sever muscle twitches, contracture on right lower extremity, difficulty breathing because of tachycardia. I was diagnosed as Acute dissemintaed encephalomyelitis (ADEM) and my Brain MRI showed diffuse demyelinization of the brain. I recovered mostly. I report this after I finished my follow up with neurology departmnts to make sure it is not a presentation of MS. I received 2 courses of steroids meanwhile that was not helpful. I still have numbness on my right leg and foot and muscle twitches. 5/28/09 Medical records received DOS 3/11/08 to 2/2/09. FINAL DIAGNOSIS: Acute disseminated encephalomyelitis, cervical stenosis. Post vaccination presented with numbness of hands feet face. Generalized weakness and fatigue. Shortness of breath, tachycardia, PVCs. Multifocal muscle twitching. 6/8/09 Hospital record (Multiple Sclerosis Center) received DOS 4/1/09. FINAL DIAGNOSIS: Acute disseminated encephalomyelitis, cervical stenosis. Follow up exam received. No new codes other than patient reports uveitis treated with prednisone eye drops in June 2008 and pericarditis treated with ibuprofen in July 2008.\ksk". "Hyperlipidemia , GERD""Medical records received DOS 3/11/08 to 2/2/09. Orchidectomy for undescended testicle. 6/8/09 Hospital record (Multiple Sclerosis Center) received DOS 4/1/09. Uveitis, Mycarditis."Lumbar puncture 2 times within 9 months interval was negative for possible MS panel. Four more Brain MRIs were negative for new lesions. EMG and NCV were Normal. Visual evoked potential was normal. Lumbar puncture did not show any elevated . During the same period patient was treated with "omeprazole , Simvastatin. 5/28/09 Medical records received DOS 3/11/08 to 2/2/09. omeprazole, simvastin, clonazepam, acetaminophen, corticosteroids. Medical records received DOS 3/11/08 to 2/2/09. Prenisone eye drops, ibuprofen.". Patient recovered.

INFLUENZA (FLUVIRIN) Side Effects Report # 344947
INFLUENZA (FLUVIRIN) side effect was reported on 04/20/2009. Male patient, 57.0 years of age, was vaccinated with INFLUENZA (FLUVIRIN). After vaccination, patient experienced the following side effects: back pain, blood product transfusion, csf cell count normal, cryptococcus antigen, diabetes mellitus"Flu like symptoms for two to three weeks. Numbness in feet - leg cramps - back pain in spinal area - problem walking (paralysis). Hospitalization - tests and treatment for Guillain-Barre (GBS) and acute rehabilitation - 30 day hospitalization.4/29/09-records received-for DOS 1/20-2/3/09-DC DX: Ascending motor sensory weakness secondary to Guillain-Barre Syndrome following recent viral respiratory tract illness 2-3 weeks prior to admission. Status post IVIG. Uncontrolled diabetes mellitus secondary to noncompliance with diet and medication. Hypertensive emergency improved. Ambulatory dysfunction secondary to gait instability. Hyponatremia. Hypokalemia. Presented with increasing gait instability and lower extremity paresthesia. Increased thirst, increased urination and fatigue. Numbness progressed to upper extremities, right facial weakness, difficulty swallowing and some dyspnea". None 4/29/09-records received-recent viral respiratory tract illness 2-3 weeks prior to admission.None 4/29/09-records received- PMH:testicular cancer. Chronic alcohol use.Hospitalization and Tests 1-21-09 4/29/09-records received-UA glucose 1000 and more than 80 ketones and 100mg/dl protein. Hemoglobin A1c 10.9. MRI brain mild atrophy. MRI thoracic spine unremarkable. MRI lumbar spine disk bulging. CSF cryp . Patient was hospitalized Patient recovered.

INFLUENZA (FLUVIRIN) Side Effects Report # 345173
INFLUENZA (FLUVIRIN) side effect was reported on 04/29/2009. Male patient, 34.0 years of age, was vaccinated with INFLUENZA (FLUVIRIN). After vaccination, patient experienced the following side effects: areflexia, areflexia, balance disorder, blood calcium increased, blood creatine phosphokinase increased"The first signs begin with a pain in my right arm three-four days after my vaccine. I was not able to raise it above my head. The pain moved to my shoulder and across to my other arm. I went to an ER a week after my vaccine and they did blood and a mono test but all came back normal and prescribed ibuprofen. Within the next week I began having difficulty walking and going up stairs. I notice pins and needs along with numbness in my toes. I went to another ER exactly a week following the first visit. They did additional blood test (CBC) and it came back normal. My blood pressure was high when I came in but it went back down to normal. They recommended a brain MRI to rule out MS. However, they stated it would have to be done by my PCP. I went the following week to my primary care physician and he wanted to do additional blood work prior to a brain MRI. He noticed I did not have any reflexes. He did tests for lupus, Lyme disease, metal, HIV. After a week waiting, all tests came back negative. At this point numbness, weakness and pins and negatives moved to my fingers and my legs. I went to a third ER a week after the PCP visit. They did some additional tests and were led to believe it was Guillain Barre. They admitted me that night. They following day I had a Brain MRI, Spinal tap and EMG. The Brain MRI came back negative. The Spinal tap showed high protein but ruled out meningitis. The EMG showed a decrease in the number of motor units. I was diagnosed with GBS. They began treating me with IV/IG over the course of 5 days. Physical and Occupational therapy began and I have been doing that ever since. I still have pain and swelling in feet. Have abnormal gait along with balance issues and struggle climbing stairs. I am taking Gabapentin and Hydrocodone for the pain and neuropathy. Records received - 05/04/2009, hosp admission 11/24/2008 to 11/30/2008. Patient previously seen and discharged by two other ED's. Admitted for evaluation of progressive weakness and paresthesias post influenza vaccinat". None"Asthma from 5-13 years of age. Allergic to penicillin, solumendrol and decadron.""Mono Test negative; Completed all blood tests, Lyme Disease Negative; Heavy Metal Negative, HIV Negative, Brain MRI was normal; Spinal Tap showed high count of protein >100. EMG showed a decrease in the number of motor units. Labs: He" . During the same period patient was treated with None. Patient was hospitalized Patient recovered.


INFLUENZA (FLUVIRIN) Side Effects Report # 345423
INFLUENZA (FLUVIRIN) side effect was reported on 05/02/2009. Male patient, 33.0 years of age, was vaccinated with INFLUENZA (FLUVIRIN). After vaccination, patient experienced the following side effects: ascites, blood glucose increased, blood test, csf oligoclonal band present, cognitive disorder"Received vaccination 10/30/07; returned to doctor with pain in left shoulder (same as vaccinated arm) within two months; began experiencing pain, numbness, cognitive changes 5 months later w/no previous history; admitted to hospital after symptoms worsened; diagnosed with Multiple Sclerosis in 04/2008; no history of any autoimmune disorders in family. 5/14/09 Hospital records received DOS 4/3/08 to 4/4/08. FINAL DIAGNOSIS: C2-C3 demyelinating lesion, single white matter lesion in the subcortical U fibers of the left frontal lobe Post vaccination ascending numbness feet, torso, hands. ICD-9 Codes: 341.9 Demyelinating diseases of central nervous system unspecified. 3488.8 Condition of brain. 477.9 Allergic rhinitis cause unspecified.". Heel PainSeasonal allergies"MRI, Blood Work, CT Scans, Lumbar Puncture, Neurological examinations. 5/14/09 Hospital records received DOS 4/3/08 to 4/4/08. LABS and DIAGNOSTICS: MRI Cervical Spine - flattening of cord at C5-C6, signal intensity C2-C3. MRI Thoracic" . Patient was hospitalized Patient recovered.

INFLUENZA (FLUVIRIN) Side Effects Report # 347265
INFLUENZA (FLUVIRIN) side effect was reported on 05/26/2009. Male patient, 14.0 years of age, was vaccinated with INFLUENZA (FLUVIRIN). After vaccination, patient experienced the following side effects: agitation, alanine aminotransferase increased, areflexia, aspartate aminotransferase increased, bacterial culture positive"Several weeks (end of November) after getting flu vaccine, client began experiencing weakness in legs with numbness in feet and toes. He began walking with a cane and 2 days later he was in a wheelchair. Family took client to the ER when he couldn't swallow. Admitted to hospital on December 3rd, 2007, and diagnosed with Guillian-Barre Syndrome. He was on life support X 17 days and in ICU X 1 month. Transferred to rehab center. 5/27/09-records submitted with report-Presented on 12/2/08 with 10 day history of increasing weakness and numbness of feet which made an ascending pattern up entire body. 4 days prior began with feelings of breathlessness and day before presenting to ED C/O trouble with swallowing and muffled speech. Elevated BP on admission 148/99 and subsequent transient increase in BP. Treated with IVIG. Mechanical ventilation required with intubation and subsequent extubation. NG feedings. DX: Guillain-Barre syndrome. One month hospitalization. Office visit follow up 1/23/09 residual weakness on both sides of face, CN VII focally affected R>L. 6/26/09 Hospital records and DC summary recieved. DOS 12/02/07 to 01/04/08. Assessment: Ascending paralysis, probable Guillain-Barre. Patient presented with ascending numbness and weakness. Nausea and vomitjng. Numbness in feet. Difficulty swallowing liquids. Unable to walk or sit up on his own. DTR's absent. Stregnth diminished upper and lower extremities. Fever, headache. Sedation/Analgesia dependence. Agitation with respiratory distress. Hypertension. IVIG administered. Transferred to rehabilitation facility. ICD-9 Codes: 357.0, 518.81, V46.11, 707.03, 292.0, 304.01, 112.0, 401.9, 075, 726.87, 041.5, 564.00, 110.5". NONENONEMedical records from Hospital included (will be faxed to VAERS) 5/27/09-records received- WBC 12.5. Positive mono spot. Positive EVB titers. Respiratory culture positive for haemophilus influenza and streptococcus pneumonia.LFTs elevated w . During the same period patient was treated with NONE. Patient was hospitalized Patient recovered.

INFLUENZA (FLUVIRIN) Side Effects Report # 350464
INFLUENZA (FLUVIRIN) side effect was reported on 06/24/2009. Male patient, 33.0 years of age, was vaccinated with INFLUENZA (FLUVIRIN). After vaccination, patient experienced the following side effects: alanine aminotransferase increased, arthralgia, aspartate aminotransferase increased, asthenia, blood albumin normal"Pt. developed onset of paresthesias (tingling) in B/L hands, neck stiffness, occas. hand numbness, hip pain, & feeling flushed on eve of 11/17/08. Flu shot given 11/4/08. NV on 11/18/08 -> referred to PCP. Eval. at ER 11/28/08 -> D/C with script for anxiolytic. Increasing ext pain -> ER 11/29/08 -> inpt. x8 days for daily plasmaphoresis. 7/1/09 Hospital records received DOS 11/30/09 to 12/07/08. Assessment: Guillain-Barre syndrome. Patient presented with tingling of hands and fingers, followed by flu-like symptoms with myalgias and arthralgias in several muscles and joints. Could barely ambulate and unable to work. Decreased muscle strength upper and lower extremities. Gait is wide-based, slow, and unsteady. Daily plasmaphoresis.". None known"None known or specified . PMH: back pain, right tibia / fibula fracture requiring ORIF.""LABS and DIAGNOSTICS: NCS - abnormal. Total CPK is 91. Alkaline Phosphatase is 97, SGOT 128, SGPT 301, Total Bilirubin is 0.4, albumin 4, globulin 3.8, BUN 16, creatinine 0.8. Hematocrit is 45, WBC 10400, platelet count 316000. CSF glucose" . During the same period patient was treated with None at time of vaccination -> currently on METOPROLOL.. Patient was hospitalized Patient recovered.