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From simple mix-ups to fatal overdoses, medication mistakes happen, on average, once a day to every hospital patient, a new report says. Nationwide, at least 1.5 million people annually are harmed from drug errors, more than half of them in nursing homes.
Many Unfavorable Drug Studies Aren’t Published. Nearly a third of antidepressant drug studies are never published in the medical literature, and nearly all of those happen to show that the drug being tests failed to work.
Only Drugs That are Safe Should be put on the Market. Drug developers are just beginning to come to grips with recent FDA oversight reforms and how they will affect drug safety. But, it appears that industry and consumer advocates are not together on how well the overhaul will be able to prevent future drug safety scandals.

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Review Actrapid Safety Reports submitted to FDA

Total Actrapid reports: 25.
Actrapid FDA safety alerts: No.
Reported deaths: 3    Reported hospitalizations: 10.
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FDA Reported Actrapid Side Effects: hypoglycaemia, hepatic steatosis, hypoglycaemic coma, respiratory tract malformation, congenital diaphragmatic hernia, atrial septal defect, brain damage, muscle spasms, hyperhidrosis, blood glucose decreased, loss of consciousness.
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Actrapid Side Effects Report #5646494-5
Physician from GERMANY reported ACTRAPID problem on Feb 19, 2008. Female patient was treated with ACTRAPID. After drug was administered, patient experienced the following problems/side effects: stevens-johnson syndrome, toxic epidermal necrolysis. ACTRAPID dosage: unknown. During the same period patient was treated with ACETAMINOPHEN, PERENTEROL, DIAZEPAM, OXAZEPAM. Patient was hospitalized. Patient recovered.

Actrapid Side Effects Report #5656724-1
ACTRAPID problem was reported by a Physician from GERMANY on Feb 27, 2008. Female patient, 36 years of age, was diagnosed with type 1 diabetes mellitus and was treated with ACTRAPID. After drug was administered, patient experienced the following problems/side effects: angioedema, blood glucose abnormal, confusional state, diplopia, injection site induration, insulin resistance, palpitations, paraesthesia, paraesthesia oral. ACTRAPID dosage: unknown. Patient recovered.

Actrapid Side Effects Report #5656771-X
Physician from GERMANY reported ACTRAPID problem on Feb 27, 2008. Female patient, 83 years of age, was diagnosed with insulin-requiring type 2 diabetes mellitus and was treated with ACTRAPID. After drug was administered, patient experienced the following problems/side effects: diplopia, erythema, injection site induration, injection site swelling, insulin resistance, pruritus, urticaria. ACTRAPID dosage: unknown. During the same period patient was treated with PROTAPHANE. Patient recovered.

Actrapid Side Effects Report #5661498-4
ACTRAPID problem was reported by a Physician from ROMANIA on Oct 15, 2007. Female patient, weighting 242.5 lb, was treated with ACTRAPID. After drug was administered, patient experienced the following problems/side effects: caesarean section, emergency care. ACTRAPID dosage: unknown. During the same period patient was treated with INSULATARD. Patient was hospitalized. Patient recovered.

Actrapid Side Effects Report #5664047-X
Health Professional from FRANCE reported ACTRAPID problem on Mar 08, 2008. Female patient, 55 years of age, was diagnosed with type 1 diabetes mellitus, insulin-requiring type 2 diabetes mellitus and was treated with ACTRAPID. After drug was administered, patient experienced the following problems/side effects: fall, glycosylated haemoglobin increased, hypoglycaemia, malaise, mitochondrial cytopathy, muscle spasms, renal failure. ACTRAPID dosage: unknown. During the same period patient was treated with INSULATARD FLEXPEN, INSULATARD FLEXPEN, DETENSIEL, TOPALGIC, DAFALGAN, KARDEGIC, COVERSYL, INNOHEP. Patient was hospitalized. Patient recovered.

Actrapid Side Effects Report #5668918-X
ACTRAPID problem was reported by a Physician from ROMANIA on Nov 02, 2007. Female patient, weighting 242.5 lb, was treated with ACTRAPID. After drug was administered, patient experienced the following problems/side effects: pre-eclampsia. ACTRAPID dosage: unknown. During the same period patient was treated with INSULATARD. Patient recovered.

Actrapid Side Effects Report #5669000-8
Physician from GERMANY reported ACTRAPID problem on Mar 10, 2008. Female patient was treated with ACTRAPID. After drug was administered, patient experienced the following problems/side effects: stevens-johnson syndrome, toxic epidermal necrolysis. ACTRAPID dosage: unknown. During the same period patient was treated with CIPROFLOXACIN, NOVALGIN, ROCEPHIN, CEFTRIAXONE, PARACETAMOL, PERENTEROL, DIAZEPAM. Patient was hospitalized. Patient recovered.

Actrapid Side Effects Report #5669065-3
ACTRAPID problem was reported by a Physician from ROMANIA on Oct 15, 2007. Female patient, weighting 242.5 lb, was treated with ACTRAPID. After drug was administered, patient experienced the following problems/side effects: caesarean section, emergency care. ACTRAPID dosage: unknown. During the same period patient was treated with INSULATARD. Patient was hospitalized. Patient recovered.

Actrapid Side Effects Report #5688847-5
Health Professional from UNITED STATES reported ACTRAPID problem on Mar 20, 2008. Male patient, weighting 156.5 lb, was diagnosed with type 2 diabetes mellitus and was treated with ACTRAPID. ACTRAPID dosage: unknown. During the same period patient was treated with PROTAPHANE, GABAPENTIN, AZATHIOPRINE. Patient died on 09/18/2007.

Actrapid Side Effects Report #5632890-9
ACTRAPID problem was reported by a Health Professional from FRANCE on Feb 12, 2008. Female patient, 55 years of age, was diagnosed with diabetes mellitus and was treated with ACTRAPID. After drug was administered, patient experienced the following problems/side effects: fall, hypoglycaemia, malaise, mitochondrial cytopathy, muscle spasms. ACTRAPID dosage: unknown. During the same period patient was treated with INSULATARD FLEXPEN, DETENSIEL, TOPALGIC, DAFALGAN, KARDEGIC, COVERSYL, INNOHEP, FONZYLANE. Patient was hospitalized. Patient recovered.

Actrapid Side Effects Report #5634448-4
Physician from ROMANIA reported ACTRAPID problem on Nov 02, 2007. Female patient, weighting 242.5 lb, was treated with ACTRAPID. After drug was administered, patient experienced the following problems/side effects: caesarean section, pre-eclampsia. ACTRAPID dosage: unknown. During the same period patient was treated with INSULATARD. Patient recovered.

Actrapid Side Effects Report #5589368-0
ACTRAPID problem was reported by a Physician from ITALY on Jan 04, 2008. Male patient was diagnosed with diabetes mellitus and was treated with ACTRAPID. After drug was administered, patient experienced the following problems/side effects: head injury, hypoglycaemia. ACTRAPID dosage: unknown. During the same period patient was treated with ACTRAPID NOVOLET, ALIFLUS. Patient was hospitalized. Patient recovered.

Actrapid Side Effects Report #5598085-2
Physician from GERMANY reported ACTRAPID problem on Jan 14, 2008. Female patient was diagnosed with insulin-requiring type 2 diabetes mellitus and was treated with ACTRAPID. After drug was administered, patient experienced the following problems/side effects: hypertensive crisis, hypoglycaemia. ACTRAPID dosage: unknown. During the same period patient was treated with ACTRAPHANE, ASPIRIN, RAMIPRIL, NITRE, METO, TORSEMIDE. Patient was hospitalized. Patient recovered.

Actrapid Side Effects Report #5608875-5
ACTRAPID problem was reported by a Physician from ITALY on Jan 24, 2008. Male patient was diagnosed with diabetes mellitus and was treated with ACTRAPID. After drug was administered, patient experienced the following problems/side effects: head injury, hypoglycaemia. ACTRAPID dosage: unknown. During the same period patient was treated with ACTRAPID NOVOLET, ALIFLUS. Patient was hospitalized. Patient recovered.

Actrapid Side Effects Report #5531519-8
Physician from GERMANY reported ACTRAPID problem on Nov 26, 2007. Male patient, weighting 163.1 lb, was diagnosed with insulin-requiring type ii diabetes mellitus and was treated with ACTRAPID. After drug was administered, patient experienced the following problems/side effects: angioedema, blood glucose increased, dermatitis allergic. ACTRAPID dosage: unknown. During the same period patient was treated with ACTRAPID NOVOLET, ACTRAPID NOVOLET, MANINIL, SIOFOR, BISOPROLOL FUMARATE, HYDROCHLOROTHIAZIDE, OMEPRAZOL. Patient recovered.

Actrapid Side Effects Report #5570549-7
ACTRAPID problem was reported by a Physician from ROMANIA on Nov 02, 2007. Female patient, weighting 242.5 lb, was treated with ACTRAPID. After drug was administered, patient experienced the following problems/side effects: caesarean section. ACTRAPID dosage: unknown. During the same period patient was treated with INSULATARD. Patient recovered.

Actrapid Side Effects Report #5572915-2
Health Professional from UNITED STATES reported ACTRAPID problem on Dec 18, 2007. Male patient, weighting 156.5 lb, was diagnosed with type 2 diabetes mellitus and was treated with ACTRAPID. ACTRAPID dosage: unknown. During the same period patient was treated with PROTAPHANE. Patient died on 09/18/2007.

Actrapid Side Effects Report #5514236-X
ACTRAPID problem was reported by a Health Professional from SWITZERLAND on Nov 08, 2007. Male patient, 19 years of age, weighting 130.1 lb, was treated with ACTRAPID. After drug was administered, patient experienced the following problems/side effects: bradycardia, hypoglycaemic coma. ACTRAPID dosage: unknown. Patient recovered.

Actrapid Side Effects Report #5515820-X
Physician from GERMANY reported ACTRAPID problem on Nov 09, 2007. Male patient, weighting 163.1 lb, was diagnosed with diabetes mellitus and was treated with ACTRAPID. After drug was administered, patient experienced the following problems/side effects: angioedema, blood glucose increased, dermatitis allergic. ACTRAPID dosage: unknown. During the same period patient was treated with ACTRAPID NOVOLET, ACTRAPID NOVOLET. Patient recovered.

Actrapid Side Effects Report #5477812-9
ACTRAPID problem was reported by a Physician from ITALY on Oct 01, 2007. Male patient was diagnosed with diabetes mellitus, rectal cancer and was treated with ACTRAPID. After drug was administered, patient experienced the following problems/side effects: erythema, laryngospasm. ACTRAPID dosage: unknown. During the same period patient was treated with ELOXATIN. Patient recovered.

Actrapid Side Effects Report #5482934-2
Physician from ITALY reported ACTRAPID problem on Oct 04, 2007. Male patient was diagnosed with diabetes mellitus, rectal cancer and was treated with ACTRAPID. After drug was administered, patient experienced the following problems/side effects: erythema, laryngospasm. ACTRAPID dosage: unknown. During the same period patient was treated with ELOXATIN. Patient recovered.

Actrapid Side Effects Report #5490603-8
ACTRAPID problem was reported by a Physician from ROMANIA on Oct 10, 2007. Female patient, weighting 242.5 lb, was treated with ACTRAPID. After drug was administered, patient experienced the following problems/side effects: caesarean section. ACTRAPID dosage: unknown. During the same period patient was treated with INSULATARD. Patient recovered.

Actrapid Side Effects Report #5452581-7
Physician from UNITED KINGDOM reported ACTRAPID problem on Sept 04, 2007. Female patient, 85 years of age, was diagnosed with hypothyroidism, hypertension, hypercholesterolaemia, cerebrovascular accident, diverticulum intestinal and was treated with ACTRAPID. After drug was administered, patient experienced the following problems/side effects: accidental overdose, bradycardia, brain damage, facial palsy, hypoglycaemia, hypotension, neuroglycopenia, unresponsive to stimuli. ACTRAPID dosage: unknown. During the same period patient was treated with GLUCOSE, LEVOTHYROXINE, AMLODIPINE, LIPITOR, ASPIRIN, LAXATIVES, HYDROCORTISONE, PANTOPRAZOLE. Patient was hospitalized. Patient died.

Actrapid Side Effects Report #5379933-8
ACTRAPID problem was reported by a Physician from AUSTRALIA on June 26, 2007. Female patient was diagnosed with diabetes mellitus and was treated with ACTRAPID. After drug was administered, patient experienced the following problems/side effects: hepatic steatosis. ACTRAPID dosage: unknown. During the same period patient was treated with PROTAPHANE. Patient recovered.

Actrapid Side Effects Report #5379933-8
Physician from AUSTRALIA reported ACTRAPID problem on June 26, 2007. Female patient was diagnosed with diabetes mellitus and was treated with ACTRAPID. After drug was administered, patient experienced the following problems/side effects: hepatic steatosis. ACTRAPID dosage: unknown. During the same period patient was treated with PROTAPHANE. Patient recovered.


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stevens-johnson syndrome, toxic epidermal necrolysis, angioedema, blood glucose abnormal, confusional state, diplopia, injection site induration, insulin resistance, palpitations, paraesthesia, paraesthesia oral, , was diagnosed with type 1 diabetes mellitus and was diagnosed with insulin-requiring type 2 diabetes mellitus and