AFLIBERCEPT Side Effects

7022557-7 | Pneumonia Necrotising
on Sep 27, 2010 Male patient from UNITED KINGDOM , 66 years of age, weighting 182.3 lb, was diagnosed with prostate cancer metastatic and was treated with Aflibercept (View Usage). Patient experienced the following unwanted or unexpected effects: pneumonia necrotising. Aflibercept dosage: . During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), PREDNISOLONE (View Prednisolone Review and Prednisolone Label ), ZOLADEX (View Zoladex Review and Zoladex Label ), CIALIS (View Cialis Review and Cialis Label ), SELENIUM ACE (View Selenium-ace Review and Selenium-ace Label ), CLEXANE (View Clexane Review and Clexane Label ). Patient was hospitalized.

7018088-0 | Adrenal Insufficiency, Fatigue, Leukopenia, Neutrophil Count, Proteinuria
Patient was taking Aflibercept (View Usage). Patient had the following side effects: adrenal insufficiency, fatigue, leukopenia, neutrophil count, proteinuria on Jan 07, 2010 from KOREA, REPUBLIC OF Additional patient health information: Female patient , 68 years of age, weighting 183.6 lb, . Aflibercept dosage: . During the same period patient was treated with OXALIPLATIN (View Oxaliplatin Review and Oxaliplatin Label ), FLUOROURACIL (View Fluorouracil Review and Fluorouracil Label ), LEUCOVORIN CALCIUM (View Leucovorin Calcium Review and Leucovorin Calcium Label ), MEGESTROL (View Megestrol Review and Megestrol Label ). Patient was hospitalized.

7007442-9 | Chest Pain
Adverse event was reported on Sep 15, 2010 by a Male patient taking Aflibercept (View Usage) (Dosage: Dose Unit: 6 Mg/kg) . Location: HUNGARY , 75 years of age, weighting 181.9 lb, After Aflibercept was administered, patient had the following side effects: chest pain (What is chest pain?). During the same period patient was treated with DOCETAXEL (Dose Unit: 75 Mg/m**2) (View Docetaxel Review and Docetaxel Label ), PREDNISOLONE (View Prednisolone Review and Prednisolone Label ), METHYLPREDNISOLONE (View Methylprednisolone Review and Methylprednisolone Label ), FAMOTIDINE (View Famotidine Review and Famotidine Label ), METOPROLOL (Dose As Used: 2 X1) (View Metoprolol Review and Metoprolol Label ), AMILORIDE HYDROCHLORIDE (View Amiloride Hydrochloride Review and Amiloride Hydrochloride Label ), HYDROCHLOROTHIAZIDE (View Hydrochlorothiazide Review and Hydrochlorothiazide Label ). Patient was hospitalized.

7004933-1 | Large Intestine Perforation
on Sep 16, 2010 Male patient from UNITED KINGDOM , 64 years of age, weighting 165.3 lb, was treated with Aflibercept (View Usage). Patient experienced the following unwanted or unexpected effects: large intestine perforation. Aflibercept dosage: . During the same period patient was treated with OXALIPLATIN (View Oxaliplatin Review and Oxaliplatin Label ), FLUOROURACIL (View Fluorouracil Review and Fluorouracil Label ), LEUCOVORIN CALCIUM (View Leucovorin Calcium Review and Leucovorin Calcium Label ), ACETAMINOPHEN (View Acetaminophen Review and Acetaminophen Label ), NULYTELY (View Nulytely Review and Nulytely Label ). Patient was hospitalized.


7004598-9 | Large Intestine Perforation
on Feb 19, 2010 Male patient from UNITED KINGDOM , 64 years of age, weighting 165.3 lb, was treated with Aflibercept (View Usage). Patient had the following side effects: large intestine perforation. Aflibercept dosage: . During the same period patient was treated with OXALIPLATIN (View Oxaliplatin Review and Oxaliplatin Label ), FLUOROURACIL (View Fluorouracil Review and Fluorouracil Label ), LEUCOVORIN CALCIUM (View Leucovorin Calcium Review and Leucovorin Calcium Label ), PARACETAMOL (View Paracetamol Review and Paracetamol Label ), NULYTELY (View Nulytely Review and Nulytely Label ). Patient was hospitalized.

6985946-2 | Adrenal Insufficiency, Fatigue, Leukopenia, Neutrophil Count, Proteinuria
Patient was taking Aflibercept (View Usage). After Aflibercept was administered, patient had the following side effects: adrenal insufficiency, fatigue, leukopenia, neutrophil count, proteinuria on Sep 06, 2010 from KOREA, REPUBLIC OF Additional patient health information: Female patient , 68 years of age, weighting 183.6 lb, . Aflibercept dosage: . During the same period patient was treated with OXALIPLATIN (View Oxaliplatin Review and Oxaliplatin Label ), FLUOROURACIL (View Fluorouracil Review and Fluorouracil Label ), LEUCOVORIN CALCIUM (View Leucovorin Calcium Review and Leucovorin Calcium Label ), MEGESTROL (View Megestrol Review and Megestrol Label ). Patient was hospitalized.

6978317-6 | Femur Fracture, Interstitial Lung Disease, Vomiting
Adverse event was reported on Sep 03, 2010 by a Male patient taking Aflibercept (View Usage) (Dosage: ) . Location: NETHERLANDS , 77 years of age, weighting 186.3 lb, Patient experienced the following unwanted or unexpected effects: femur fracture, interstitial lung disease, vomiting. During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), PREDNISONE (View Prednisone Review and Prednisone Label ), ZOLADEX (View Zoladex Review and Zoladex Label ), PERSANTINE (View Persantine Review and Persantine Label ), ZOCOR (View Zocor Review and Zocor Label ), IMODIUM (View Imodium Review and Imodium Label ). Patient was hospitalized.

6976195-2 | Hyperthyroidism, Malaise, Mucosal Inflammation
on Sep 02, 2010 Male patient from NETHERLANDS , 77 years of age, weighting 191.8 lb, was diagnosed with prostate cancer metastatic and was treated with Aflibercept (View Usage). Patient had the following side effects: hyperthyroidism, malaise, mucosal inflammation. Aflibercept dosage: . During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), PREDNISONE (View Prednisone Review and Prednisone Label ), ZOLADEX (View Zoladex Review and Zoladex Label ), PERSANTIN (View Persantin Review and Persantin Label ), ZOCOR (View Zocor Review and Zocor Label ), IMODIUM (View Imodium Review and Imodium Label ). Patient was hospitalized.

6973227-2 | Proteinuria, Urinary Tract Infection
on Sep 07, 2010 Female patient from FRANCE , 71 years of age, weighting 119.0 lb, was treated with Aflibercept (View Usage). After Aflibercept was administered, patient had the following side effects: proteinuria, urinary tract infection (What is urinary tract infection?). Aflibercept dosage: . During the same period patient was treated with TAXOTERE (View Taxotere Review and Taxotere Label ), DOLIPRANE (View Doliprane Review and Doliprane Label ), ACETAMINOPHEN W/ PROPOXYPHENE HCL (View Acetaminophen W/ Propoxyphene Hcl Review and Acetaminophen W/ Propoxyphene Hcl Label ), TRIATEC (View Triatec Review and Triatec Label ), NORSET (View Norset Review and Norset Label ), LOGIRENE (View Logirene Review and Logirene Label ). Patient was hospitalized.

6967282-3 | Pigmentary Glaucoma
Patient was taking Aflibercept (View Usage). Patient experienced the following unwanted or unexpected effects: pigmentary glaucoma on Aug 26, 2010 from CANADA Additional patient health information: Male patient , 61 years of age, weighting 148.6 lb, . Aflibercept dosage: Dose Unit: 6 Mg/kg. During the same period patient was treated with DOCETAXEL (Dose Unit: 75 Mg/m**2) (View Docetaxel Review and Docetaxel Label ), PREDNISONE (Dose Unit: 5 Mg) (View Prednisone Review and Prednisone Label ), ENALAPRIL (Dose As Used: Unk) (View Enalapril Review and Enalapril Label ), HYDROCHLOROTHIAZIDE (Dose As Used: Unk) (View Hydrochlorothiazide Review and Hydrochlorothiazide Label ), SLOW K (Dose As Used: Unk) (View Slow-k Review and Slow-k Label ), ASPIRIN (Dose As Used: Unk) (View Aspirin Review and Aspirin Label ), MULTI VITAMINS (Dose As Used: Unk) (View Multi-vitamins Review and Multi-vitamins Label ), WATER (Dose As Used: Unk) (View Water Review and Water Label ).

6966761-2 | Pleural Effusion
Adverse event was reported on Sep 01, 2010 by a Male patient taking Aflibercept (View Usage) (Dosage: ) was diagnosed with prostate cancer metastatic and. Location: TAIWAN, PROVINCE OF CHINA , 78 years of age, weighting 119.0 lb, Patient had the following side effects: pleural effusion. During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), PREDNISOLONE (View Prednisolone Review and Prednisolone Label ), PLENDIL (View Plendil Review and Plendil Label ), TENORMIN (View Tenormin Review and Tenormin Label ). Patient was hospitalized.

6966755-7 | Pigmentary Glaucoma
on Aug 26, 2010 Male patient from CANADA , 61 years of age, weighting 148.6 lb, was treated with Aflibercept (View Usage). After Aflibercept was administered, patient had the following side effects: pigmentary glaucoma. Aflibercept dosage: Dose Unit: 6 Mg/kg. During the same period patient was treated with DOCETAXEL (Dose Unit: 75 Mg/m**2) (View Docetaxel Review and Docetaxel Label ), PREDNISONE (Dose Unit: 5 Mg) (View Prednisone Review and Prednisone Label ), ENALAPRIL (Dose As Used: Unk) (View Enalapril Review and Enalapril Label ), HYDROCHLOROTHIAZIDE (Dose As Used: Unk) (View Hydrochlorothiazide Review and Hydrochlorothiazide Label ), SLOW K (Dose As Used: Unk) (View Slow-k Review and Slow-k Label ), ASPIRIN (Dose As Used: Unk) (View Aspirin Review and Aspirin Label ), MULTI VITAMINS (Dose As Used: Unk) (View Multi-vitamins Review and Multi-vitamins Label ), WATER (Dose As Used: Unk) (View Water Review and Water Label ).

6964811-0 | Disease Progression
on Aug 31, 2010 Male patient from CHILE , 77 years of age, weighting 134.5 lb, was treated with Aflibercept (View Usage). Patient experienced the following unwanted or unexpected effects: disease progression. Aflibercept dosage: . During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), PREDNISONE TAB (View Prednisone Tab Review and Prednisone Tab Label ), DECAPEPTYL /SWE/ (View Decapeptyl /swe/ Review and Decapeptyl /swe/ Label ), FLUOXETINE (View Fluoxetine Review and Fluoxetine Label ), OMEPRAZOLE (View Omeprazole Review and Omeprazole Label ), METOCLOPRAMIDE (View Metoclopramide Review and Metoclopramide Label ).

6960142-3 | Adrenal Insufficiency, Fatigue, Leukopenia, Neutrophil Count, Peritonitis, Proteinuria
Patient was taking Aflibercept (View Usage). Patient had the following side effects: adrenal insufficiency, fatigue, leukopenia, neutrophil count, peritonitis, proteinuria on Aug 26, 2010 from KOREA, REPUBLIC OF Additional patient health information: Female patient , 68 years of age, weighting 183.6 lb, . Aflibercept dosage: . During the same period patient was treated with OXALIPLATIN (View Oxaliplatin Review and Oxaliplatin Label ), FLUOROURACIL (View Fluorouracil Review and Fluorouracil Label ), LEUCOVORIN CALCIUM (View Leucovorin Calcium Review and Leucovorin Calcium Label ), MEGESTROL (View Megestrol Review and Megestrol Label ). Patient was hospitalized.

6955173-3 | Pneumonia Necrotising
Adverse event was reported on Aug 19, 2010 by a Male patient taking Aflibercept (View Usage) (Dosage: ) was diagnosed with prostate cancer metastatic and. Location: UNITED KINGDOM , 66 years of age, weighting 182.3 lb, After Aflibercept was administered, patient had the following side effects: pneumonia necrotising. During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), PREDNISOLONE (View Prednisolone Review and Prednisolone Label ), ZOLADEX (View Zoladex Review and Zoladex Label ), CIALIS (View Cialis Review and Cialis Label ), SELENIUM ACE (View Selenium-ace Review and Selenium-ace Label ), CLEXANE (View Clexane Review and Clexane Label ). Patient was hospitalized.

6955113-7 | Dyspnoea, Femur Fracture, Vomiting
on Aug 24, 2010 Male patient from NETHERLANDS , 77 years of age, weighting 186.3 lb, was treated with Aflibercept (View Usage). Patient experienced the following unwanted or unexpected effects: dyspnoea, femur fracture, vomiting. Aflibercept dosage: . During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), PREDNISONE (View Prednisone Review and Prednisone Label ), ZOLADEX (View Zoladex Review and Zoladex Label ), PERSANTINE (View Persantine Review and Persantine Label ), ZOCOR (View Zocor Review and Zocor Label ), IMODIUM (View Imodium Review and Imodium Label ). Patient was hospitalized.

6940219-9 | Electrocardiogram Abnormal, Hypotension
on Aug 19, 2010 Male patient from UNITED STATES , 75 years of age, weighting 149.9 lb, was diagnosed with prostate cancer metastatic and was treated with Aflibercept (View Usage). Patient had the following side effects: electrocardiogram abnormal, hypotension. Aflibercept dosage: . During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), PREDNISONE (View Prednisone Review and Prednisone Label ), ZOLADEX (View Zoladex Review and Zoladex Label ), HYTRIN (View Hytrin Review and Hytrin Label ), LIPITOR (View Lipitor Review and Lipitor Label ), TOPROL XL (View Toprol-xl Review and Toprol-xl Label ). Patient was hospitalized.

6935764-6 | Pleural Effusion
Patient was taking Aflibercept (View Usage). After Aflibercept was administered, patient had the following side effects: pleural effusion on Aug 18, 2010 from TAIWAN, PROVINCE OF CHINA Additional patient health information: Male patient , 78 years of age, weighting 119.0 lb, was diagnosed with prostate cancer metastatic and. Aflibercept dosage: . During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), PREDNISOLONE (View Prednisolone Review and Prednisolone Label ), PLENDIL (View Plendil Review and Plendil Label ), TENORMIN (View Tenormin Review and Tenormin Label ). Patient was hospitalized.

6925035-6 | Lymphorrhoea
Adverse event was reported on Aug 03, 2010 by a Female patient taking Aflibercept (View Usage) (Dosage: ) . Location: GERMANY , 61 years of age, weighting 121.3 lb, Patient experienced the following unwanted or unexpected effects: lymphorrhoea. During the same period patient was treated with OXALIPLATIN (View Oxaliplatin Review and Oxaliplatin Label ), FLUOROURACIL (View Fluorouracil Review and Fluorouracil Label ), LEUCOVORIN CALCIUM (View Leucovorin Calcium Review and Leucovorin Calcium Label ). Patient was hospitalized.

6920815-5 | Hyperkalaemia
on Aug 06, 2010 Male patient from KOREA, REPUBLIC OF , 47 years of age, weighting 146.4 lb, was diagnosed with non-small cell lung cancer metastatic and was treated with Aflibercept (View Usage). Patient had the following side effects: hyperkalaemia. Aflibercept dosage: . During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), CORTICOSTEROIDS (View Corticosteroids Review and Corticosteroids Label ). Patient was hospitalized.

6917903-6 | Pneumonia Necrotising
on Jul 30, 2010 Male patient from UNITED KINGDOM , 66 years of age, weighting 182.3 lb, was diagnosed with prostate cancer metastatic and was treated with Aflibercept (View Usage). After Aflibercept was administered, patient had the following side effects: pneumonia necrotising. Aflibercept dosage: . During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), PREDNISOLONE (View Prednisolone Review and Prednisolone Label ), ZOLADEX (View Zoladex Review and Zoladex Label ), CIALIS (View Cialis Review and Cialis Label ), SELENIUM ACE (View Selenium-ace Review and Selenium-ace Label ), CLEXANE (View Clexane Review and Clexane Label ). Patient was hospitalized.

6916814-X | Ileal Perforation
Patient was taking Aflibercept (View Usage). Patient experienced the following unwanted or unexpected effects: ileal perforation on Jan 20, 2010 from SPAIN Additional patient health information: Female patient , 49 years of age, . Aflibercept dosage: . During the same period patient was treated with OXALIPLATIN (View Oxaliplatin Review and Oxaliplatin Label ), FLUOROURACIL (View Fluorouracil Review and Fluorouracil Label ), LEUCOVORIN CALCIUM (View Leucovorin Calcium Review and Leucovorin Calcium Label ), OXYCONTIN (View Oxycontin Review and Oxycontin Label ), OXYCODONE HCL (View Oxycodone Hcl Review and Oxycodone Hcl Label ), NAPROSYN (View Naprosyn Review and Naprosyn Label ), DUPHALAC /NET/ (View Duphalac /net/ Review and Duphalac /net/ Label ). Patient was hospitalized.

6883076-1 | Dyspnoea, Supraventricular Tachycardia
Adverse event was reported on Jul 26, 2010 by a Male patient taking Aflibercept (View Usage) (Dosage: Dose Unit: 6 Mg/kg) was diagnosed with non-small cell lung cancer and. Location: TURKEY , 70 years of age, Patient had the following side effects: dyspnoea, supraventricular tachycardia. During the same period patient was treated with DOCETAXEL (Dose Unit: 75 Mg/m**2) (View Docetaxel Review and Docetaxel Label ), DILTIAZEM (View Diltiazem Review and Diltiazem Label ), IRBESARTAN (View Irbesartan Review and Irbesartan Label ), ECOPIRIN (View Ecopirin Review and Ecopirin Label ), CORTICOSTEROIDS (View Corticosteroids Review and Corticosteroids Label ).

6855877-7 | Pneumothorax
on Jul 13, 2010 Male patient from JAPAN , 74 years of age, weighting 114.6 lb, was treated with Aflibercept (View Usage). After Aflibercept was administered, patient had the following side effects: pneumothorax. Aflibercept dosage: . During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), PRIMPERAN TAB (View Primperan Tab Review and Primperan Tab Label ). Patient was hospitalized.

6843642-6 | Hypocalcaemia, Neutropenia
on Jun 21, 2010 Male patient from UNITED KINGDOM , 67 years of age, weighting 243.6 lb, was treated with Aflibercept (View Usage). Patient experienced the following unwanted or unexpected effects: hypocalcaemia, neutropenia. Aflibercept dosage: . During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), PREDNISOLONE (View Prednisolone Review and Prednisolone Label ), ZOLADEX (View Zoladex Review and Zoladex Label ), TAMSULOSIN HCL (View Tamsulosin Hcl Review and Tamsulosin Hcl Label ), OMEPRAZOLE (View Omeprazole Review and Omeprazole Label ), SYMBICORT (View Symbicort Review and Symbicort Label ), CHONDROITIN W/GLUCOSAMINE (View Chondroitin W/glucosamine Review and Chondroitin W/glucosamine Label ), VITAMIN C WITH ZINC (View Vitamin C With Zinc Review and Vitamin C With Zinc Label ). Patient was hospitalized.

6835624-5 | Adrenal Insufficiency, Fatigue, Leukopenia, Neutrophil Count, Peritonitis, Proteinuria
Patient was taking Aflibercept (View Usage). Patient had the following side effects: adrenal insufficiency, fatigue, leukopenia, neutrophil count, peritonitis, proteinuria on Jul 06, 2010 from KOREA, REPUBLIC OF Additional patient health information: Female patient , 68 years of age, weighting 183.6 lb, . Aflibercept dosage: . During the same period patient was treated with OXALIPLATIN (View Oxaliplatin Review and Oxaliplatin Label ), FLUOROURACIL (View Fluorouracil Review and Fluorouracil Label ), LEUCOVORIN CALCIUM (View Leucovorin Calcium Review and Leucovorin Calcium Label ), MEGESTROL ACETATE (View Megestrol Acetate Review and Megestrol Acetate Label ). Patient was hospitalized.

6831225-3 | Pleural Effusion
Adverse event was reported on Jun 21, 2010 by a Male patient taking Aflibercept (View Usage) (Dosage: ) was diagnosed with prostate cancer metastatic and. Location: TAIWAN, PROVINCE OF CHINA , 78 years of age, weighting 119.0 lb, After Aflibercept was administered, patient had the following side effects: pleural effusion. During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), PREDNISOLONE (View Prednisolone Review and Prednisolone Label ), PLENDIL (View Plendil Review and Plendil Label ), TENORMIN (View Tenormin Review and Tenormin Label ). Patient was hospitalized.

6830982-X | Atrial Fibrillation, Autoimmune Thrombocytopenia
on Jun 30, 2010 Male patient from CZECH REPUBLIC , 72 years of age, weighting 231.5 lb, was treated with Aflibercept (View Usage). Patient experienced the following unwanted or unexpected effects: atrial fibrillation (What is atrial fibrillation?), autoimmune thrombocytopenia. Aflibercept dosage: Dose Unit: 6 Mg/kg. During the same period patient was treated with DOCETAXEL (Dose Unit: 75 Mg/m**2) (View Docetaxel Review and Docetaxel Label ), PREDNISONE (View Prednisone Review and Prednisone Label ), URINARY ANTISPASMODICS (View Urinary Antispasmodics Review and Urinary Antispasmodics Label ), PROTHIADEN /UNK/ (View Prothiaden /unk/ Review and Prothiaden /unk/ Label ), GODASAL (View Godasal Review and Godasal Label ), HEPARIN (View Heparin Review and Heparin Label ). Patient was hospitalized.

6826385-4 | Pneumonia, Restrictive Cardiomyopathy
on Jul 02, 2010 Male patient from CHILE , 69 years of age, weighting 173.9 lb, was diagnosed with prostate cancer metastatic and was treated with Aflibercept (View Usage). Patient had the following side effects: pneumonia (What is pneumonia?), restrictive cardiomyopathy. Aflibercept dosage: . During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), PREDNISONE (View Prednisone Review and Prednisone Label ), ZOLADEX (View Zoladex Review and Zoladex Label ), ANTITHROMBOTIC AGENTS (View Antithrombotic Agents Review and Antithrombotic Agents Label ), METFORMIN HCL (View Metformin Hcl Review and Metformin Hcl Label ), GLIBENCLAMIDE (View Glibenclamide Review and Glibenclamide Label ). Patient was hospitalized.

6812226-8 | Dyspnoea, Femur Fracture, Vomiting
Patient was taking Aflibercept (View Usage). After Aflibercept was administered, patient had the following side effects: dyspnoea, femur fracture, vomiting on Jun 29, 2010 from NETHERLANDS Additional patient health information: Male patient , 77 years of age, weighting 186.3 lb, . Aflibercept dosage: . During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), PREDNISONE TAB (View Prednisone Tab Review and Prednisone Tab Label ), ZOLADEX (View Zoladex Review and Zoladex Label ), PERSANTINE (View Persantine Review and Persantine Label ), ZOCOR (View Zocor Review and Zocor Label ), IMODIUM (View Imodium Review and Imodium Label ). Patient was hospitalized.

6812201-3 | Febrile Neutropenia, Hyperthyroidism, Malaise
Adverse event was reported on Jun 29, 2010 by a Male patient taking Aflibercept (View Usage) (Dosage: ) was diagnosed with prostate cancer metastatic and. Location: NETHERLANDS , 77 years of age, weighting 191.8 lb, Patient experienced the following unwanted or unexpected effects: febrile neutropenia, hyperthyroidism, malaise. During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), PREDNISONE (View Prednisone Review and Prednisone Label ), ZOLADEX (View Zoladex Review and Zoladex Label ), PERSANTINE (View Persantine Review and Persantine Label ), ZOCOR (View Zocor Review and Zocor Label ), IMODIUM (View Imodium Review and Imodium Label ). Patient was hospitalized.

6812192-5 | Hyperkalaemia
on Jun 28, 2010 Male patient from KOREA, REPUBLIC OF , 47 years of age, weighting 146.4 lb, was diagnosed with non-small cell lung cancer metastatic and was treated with Aflibercept (View Usage). Patient had the following side effects: hyperkalaemia. Aflibercept dosage: . During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), CORTICOSTEROIDS (View Corticosteroids Review and Corticosteroids Label ). Patient was hospitalized.

6803315-2 | Proteinuria, Urinary Tract Infection
on Jun 22, 2010 Female patient from FRANCE , 71 years of age, weighting 119.0 lb, was treated with Aflibercept (View Usage). After Aflibercept was administered, patient had the following side effects: proteinuria, urinary tract infection (What is urinary tract infection?). Aflibercept dosage: . During the same period patient was treated with TAXOTERE (View Taxotere Review and Taxotere Label ), DOLIPRANE (View Doliprane Review and Doliprane Label ), DI ANTALVIC (View Di Antalvic Review and Di Antalvic Label ), TRIATEC (View Triatec Review and Triatec Label ), NORSET (View Norset Review and Norset Label ), LOGIRENE (View Logirene Review and Logirene Label ). Patient was hospitalized.

6803026-3 | Anal Fissure, Anal Fistula
Patient was taking Aflibercept (View Usage). Patient experienced the following unwanted or unexpected effects: anal fissure, anal fistula on May 17, 2010 from GERMANY Additional patient health information: Male patient , 59 years of age, weighting 174.2 lb, . Aflibercept dosage: . During the same period patient was treated with OXALIPLATIN (View Oxaliplatin Review and Oxaliplatin Label ), FLUOROURACIL (View Fluorouracil Review and Fluorouracil Label ), LEUCOVORIN CALCIUM (View Leucovorin Calcium Review and Leucovorin Calcium Label ), ZOFRAN (View Zofran Review and Zofran Label ). Patient was hospitalized.

6769515-5 | Hyperkalaemia
Adverse event was reported on Jun 09, 2010 by a Male patient taking Aflibercept (View Usage) (Dosage: ) was diagnosed with non-small cell lung cancer metastatic and. Location: KOREA, REPUBLIC OF , 47 years of age, weighting 146.4 lb, Patient had the following side effects: hyperkalaemia. During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), CORTICOSTEROIDS (View Corticosteroids Review and Corticosteroids Label ), DEXAMETHASONE (View Dexamethasone Review and Dexamethasone Label ), DIAZEPAM (View Diazepam Review and Diazepam Label ). Patient was hospitalized.

6766098-0 | Enterocutaneous Fistula, Infection
on Jun 03, 2010 Female patient from UNITED STATES , 60 years of age, weighting 167.6 lb, was diagnosed with ovarian epithelial cancer and was treated with Aflibercept (View Usage). After Aflibercept was administered, patient had the following side effects: enterocutaneous fistula, infection (What is infection?). Aflibercept dosage: . During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), FRAGMIN /SWE/ (View Fragmin /swe/ Review and Fragmin /swe/ Label ), TOPROL XL (View Toprol-xl Review and Toprol-xl Label ), VICODIN (View Vicodin Review and Vicodin Label ). Patient was hospitalized.

6762500-9 | Dyspnoea, Femur Fracture, Vomiting
on Jun 01, 2010 Male patient from NETHERLANDS , 77 years of age, weighting 186.3 lb, was treated with Aflibercept (View Usage). Patient experienced the following unwanted or unexpected effects: dyspnoea, femur fracture, vomiting. Aflibercept dosage: . During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), PREDNISONE (View Prednisone Review and Prednisone Label ), ZOLADEX (View Zoladex Review and Zoladex Label ), PERSANTINE (View Persantine Review and Persantine Label ), ZOCOR (View Zocor Review and Zocor Label ), IMODIUM (View Imodium Review and Imodium Label ). Patient was hospitalized.

6761174-0 | Haemoglobin Decreased, Hypoglycaemia
Patient was taking Aflibercept (View Usage). Patient had the following side effects: haemoglobin decreased, hypoglycaemia on Jun 02, 2010 from UNITED STATES Additional patient health information: Male patient , 76 years of age, weighting 192.2 lb, . Aflibercept dosage: . During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), PREDNISONE (View Prednisone Review and Prednisone Label ), GLANIL (View Glanil Review and Glanil Label ), SAW PALMETTO (View Saw Palmetto Review and Saw Palmetto Label ), SENOKOT /UNK/ (View Senokot /unk/ Review and Senokot /unk/ Label ), PEPCID (View Pepcid Review and Pepcid Label ). Patient was hospitalized.

6759991-6 | Pneumothorax
Adverse event was reported on Mar 02, 2010 by a Male patient taking Aflibercept (View Usage) (Dosage: ) . Location: JAPAN , 74 years of age, weighting 114.6 lb, After Aflibercept was administered, patient had the following side effects: pneumothorax. During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), PRIMPERAN TAB (View Primperan Tab Review and Primperan Tab Label ). Patient was hospitalized.

6758036-1 |
on Jun 01, 2010 Male patient from BRAZIL , 43 years of age, weighting 156.5 lb, was diagnosed with non-small cell lung cancer and was treated with Aflibercept (View Usage). . Aflibercept dosage: . During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), IBUPROFENO (View Ibuprofeno Review and Ibuprofeno Label ), PARACETAMOL (View Paracetamol Review and Paracetamol Label ).

6756793-1 | Large Intestine Perforation
on Jun 01, 2010 Male patient from UNITED KINGDOM , 64 years of age, weighting 165.3 lb, was treated with Aflibercept (View Usage). Patient had the following side effects: large intestine perforation. Aflibercept dosage: . During the same period patient was treated with OXALIPLATIN (View Oxaliplatin Review and Oxaliplatin Label ), FLUOROURACIL (View Fluorouracil Review and Fluorouracil Label ), LEUCOVORIN CALCIUM (View Leucovorin Calcium Review and Leucovorin Calcium Label ), AMLODIPINE (View Amlodipine Review and Amlodipine Label ), PARACETAMOL (View Paracetamol Review and Paracetamol Label ), NULYTELY (View Nulytely Review and Nulytely Label ). Patient was hospitalized.

6756290-3 | Intestinal Perforation, Neutropenic Sepsis, Pneumothorax
Patient was taking Aflibercept (View Usage). After Aflibercept was administered, patient had the following side effects: intestinal perforation, neutropenic sepsis, pneumothorax on May 28, 2010 from AUSTRALIA Additional patient health information: Male patient , 71 years of age, . Aflibercept dosage: . During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), PREDNISONE (View Prednisone Review and Prednisone Label ), LUCRIN (View Lucrin Review and Lucrin Label ), LEVOTHYROXINE SODIUM (View Levothyroxine Sodium Review and Levothyroxine Sodium Label ), OLMETEC (View Olmetec Review and Olmetec Label ). Patient was hospitalized.

6754064-0 | Adrenal Insufficiency, Fatigue, Leukopenia, Neutrophil Count, Peritonitis, Proteinuria
Adverse event was reported on May 24, 2010 by a Female patient taking Aflibercept (View Usage) (Dosage: ) . Location: KOREA, REPUBLIC OF , 68 years of age, weighting 183.6 lb, Patient experienced the following unwanted or unexpected effects: adrenal insufficiency, fatigue, leukopenia, neutrophil count, peritonitis, proteinuria. During the same period patient was treated with OXALIPLATIN (View Oxaliplatin Review and Oxaliplatin Label ), FLUOROURACIL (View Fluorouracil Review and Fluorouracil Label ), LEUCOVORIN CALCIUM (View Leucovorin Calcium Review and Leucovorin Calcium Label ), MEGESTROL ACETATE (View Megestrol Acetate Review and Megestrol Acetate Label ). Patient was hospitalized.

6748913-X | Dyspnoea, Femur Fracture, Vomiting
on May 21, 2010 Male patient from NETHERLANDS , 77 years of age, weighting 186.3 lb, was treated with Aflibercept (View Usage). Patient had the following side effects: dyspnoea, femur fracture, vomiting. Aflibercept dosage: . During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), PREDNISONE TAB (View Prednisone Tab Review and Prednisone Tab Label ), ZOLADEX (View Zoladex Review and Zoladex Label ), PERSANTINE (View Persantine Review and Persantine Label ), ZOCOR (View Zocor Review and Zocor Label ), IMODIUM (View Imodium Review and Imodium Label ). Patient was hospitalized.

6743768-1 | Pancreatitis Acute
on May 24, 2010 Male patient from RUSSIAN FEDERATION , 51 years of age, weighting 132.3 lb, was diagnosed with non-small cell lung cancer metastatic and was treated with Aflibercept (View Usage). After Aflibercept was administered, patient had the following side effects: pancreatitis acute. Aflibercept dosage: . During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), OMEPRAZOLE (View Omeprazole Review and Omeprazole Label ), CORTICOSTEROIDS (View Corticosteroids Review and Corticosteroids Label ). Patient was hospitalized.

6741736-7 | Hypocalcaemia, Neutropenia
Patient was taking Aflibercept (View Usage). Patient experienced the following unwanted or unexpected effects: hypocalcaemia, neutropenia on May 20, 2010 from UNITED KINGDOM Additional patient health information: Male patient , 67 years of age, weighting 243.6 lb, . Aflibercept dosage: . During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), PREDNISOLONE (View Prednisolone Review and Prednisolone Label ), ZOLADEX (View Zoladex Review and Zoladex Label ), TAMSULOSIN HCL (View Tamsulosin Hcl Review and Tamsulosin Hcl Label ), OMEPRAZOLE (View Omeprazole Review and Omeprazole Label ), SYMBICORT (View Symbicort Review and Symbicort Label ), CHONDROITIN W/GLUCOSAMINE (View Chondroitin W/glucosamine Review and Chondroitin W/glucosamine Label ), VITAMIN C WITH ZINC (View Vitamin C With Zinc Review and Vitamin C With Zinc Label ). Patient was hospitalized.

6728341-3 | Ventricular Arrhythmia
Adverse event was reported on May 11, 2010 by a Male patient taking Aflibercept (View Usage) (Dosage: ) . Location: GERMANY , 56 years of age, weighting 262.4 lb, Patient had the following side effects: ventricular arrhythmia. During the same period patient was treated with OXALIPLATIN (View Oxaliplatin Review and Oxaliplatin Label ), FLUOROURACIL (View Fluorouracil Review and Fluorouracil Label ), LEUCOVORIN CALCIUM (View Leucovorin Calcium Review and Leucovorin Calcium Label ), EBRANTIL (View Ebrantil Review and Ebrantil Label ), NITROGLYCERIN (View Nitroglycerin Review and Nitroglycerin Label ), CANDESARTAN CILEXETIL (View Candesartan Cilexetil Review and Candesartan Cilexetil Label ). Patient was hospitalized.

6727584-2 | Pancreatitis Acute
on May 11, 2010 Male patient from RUSSIAN FEDERATION , 51 years of age, weighting 132.3 lb, was diagnosed with non-small cell lung cancer metastatic and was treated with Aflibercept (View Usage). After Aflibercept was administered, patient had the following side effects: pancreatitis acute. Aflibercept dosage: . During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), OMEPRAZOLE (View Omeprazole Review and Omeprazole Label ), CORTICOSTEROIDS (View Corticosteroids Review and Corticosteroids Label ). Patient was hospitalized.

6727326-0 | Hyperkalaemia
on May 11, 2010 Male patient from KOREA, REPUBLIC OF , 47 years of age, weighting 146.4 lb, was diagnosed with non-small cell lung cancer metastatic and was treated with Aflibercept (View Usage). Patient experienced the following unwanted or unexpected effects: hyperkalaemia. Aflibercept dosage: . During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), CORTICOSTEROIDS (View Corticosteroids Review and Corticosteroids Label ), DEXAMETHASONE (View Dexamethasone Review and Dexamethasone Label ), DIAZEPAM (View Diazepam Review and Diazepam Label ). Patient was hospitalized.

6727310-7 | Acute Respiratory Failure, Hypertensive Crisis
Patient was taking Aflibercept (View Usage). Patient had the following side effects: acute respiratory failure, hypertensive crisis on May 10, 2010 from HUNGARY Additional patient health information: Male patient , 78 years of age, weighting 132.3 lb, . Aflibercept dosage: . During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), PREDNISONE (View Prednisone Review and Prednisone Label ), ZOLADEX (View Zoladex Review and Zoladex Label ), NEBIVOLOL HCL (View Nebivolol Hcl Review and Nebivolol Hcl Label ). Patient was hospitalized.