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From simple mix-ups to fatal overdoses, medication mistakes happen, on average, once a day to every hospital patient, a new report says. Nationwide, at least 1.5 million people annually are harmed from drug errors, more than half of them in nursing homes.
Many Unfavorable Drug Studies Aren’t Published. Nearly a third of antidepressant drug studies are never published in the medical literature, and nearly all of those happen to show that the drug being tests failed to work.
Only Drugs That are Safe Should be put on the Market. Drug developers are just beginning to come to grips with recent FDA oversight reforms and how they will affect drug safety. But, it appears that industry and consumer advocates are not together on how well the overhaul will be able to prevent future drug safety scandals.

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Review Alkeran Safety Reports submitted to FDA

Total Alkeran reports: 63.
Alkeran FDA safety alerts: No.
Reported deaths: 22    Reported hospitalizations: 43.
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FDA Reported Alkeran Side Effects: febrile neutropenia, pyrexia, osteonecrosis, sepsis, stomatitis, cystitis haemorrhagic, anaemia, diarrhoea, pneumonia respiratory syncytial viral, bone marrow failure, abdominal pain.
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Alkeran Side Effects Report #5656967-7
Physician from JAPAN reported ALKERAN problem on Mar 06, 2008. Female patient, 53 years of age, weighting 130.1 lb, was diagnosed with stem cell transplant and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, cellulitis, herpes zoster, histiocytosis haematophagic, pyrexia. ALKERAN dosage: 300MG PER DAY. During the same period patient was treated with NEUTROGIN, KYTRIL, PRIMPERAN, HYDROCORTONE, TIENAM, VANCOMYCIN, DIFLUCAN, CIPROFLOXACIN. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5661696-X
ALKERAN problem was reported by a Physician from CANADA on Mar 05, 2008. Male patient was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: blood test abnormal, platelet count decreased, red blood cell count decreased. ALKERAN dosage: 2MG PER DAY. During the same period patient was treated with PREDNISONE. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5664503-4
Physician from JAPAN reported ALKERAN problem on Mar 10, 2008. Female patient, 25 years of age, was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: haemolytic anaemia, hyperaesthesia, platelet count decreased, renal impairment, thrombotic microangiopathy. ALKERAN dosage: 140MGM2 PER DAY. During the same period patient was treated with RANIMUSTINE, ETOPOSIDE. Patient recovered.

Alkeran Side Effects Report #5664504-6
ALKERAN problem was reported by a Physician from JAPAN on Mar 10, 2008. Male patient, 40 years of age, was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: hyperaesthesia, thrombotic microangiopathy. ALKERAN dosage: 140MGM2 PER DAY. During the same period patient was treated with RANIMUSTINE, ETOPOSIDE, RITUXIMAB. Patient recovered.

Alkeran Side Effects Report #5670930-1
Physician from JAPAN reported ALKERAN problem on Mar 17, 2008. Male patient, 64 years of age, was diagnosed with stem cell transplant and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: febrile neutropenia, mucous membrane disorder. ALKERAN dosage: 140MGM2 PER DAY. Patient recovered.

Alkeran Side Effects Report #5615321-4
ALKERAN problem was reported by a Physician from JAPAN on Feb 04, 2008. Male patient, 59 years of age, weighting 121.3 lb, was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: mucous membrane disorder, nausea. ALKERAN dosage: 225MG PER DAY. During the same period patient was treated with FLUDARA, SANDIMMUNE. Patient recovered.

Alkeran Side Effects Report #5615624-3
Physician from JAPAN reported ALKERAN problem on Feb 01, 2008. Female patient, 53 years of age, weighting 130.1 lb, was diagnosed with stem cell transplant and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: cellulitis, herpes zoster, histiocytosis haematophagic. ALKERAN dosage: 300MG PER DAY. During the same period patient was treated with NEUTROGIN, KYTRIL, PRIMPERAN, HYDROCORTONE, TIENAM, VANCOMYCIN, DIFLUCAN, CIPROFLOXACIN. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5623110-X
ALKERAN problem was reported by a Health Professional from UNITED STATES on Feb 06, 2008. Female patient, 61 years of age, weighting 167.3 lb, was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: complications of transplant surgery, disease progression, interstitial lung disease, respiratory failure. ALKERAN dosage: unknown. During the same period patient was treated with REVLIMID. Patient died on 01/16/2007.

Alkeran Side Effects Report #5630586-0
Physician from JAPAN reported ALKERAN problem on Feb 14, 2008. Male patient, 48 years of age, was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: cardiac arrest. ALKERAN dosage: 6MG TWICE PER DAY. Patient recovered.

Alkeran Side Effects Report #5630758-5
ALKERAN problem was reported by a Physician from JAPAN on Feb 15, 2008. Female patient, 50 years of age, weighting 81.57 lb, was diagnosed with stem cell transplant and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: cerebral haemorrhage, disseminated intravascular coagulation, enterocolitis, febrile neutropenia, mouth ulceration, pyrexia. ALKERAN dosage: 70MG PER DAY. During the same period patient was treated with CYCLOSPORINE. Patient died on 10/06/2007.

Alkeran Side Effects Report #5632107-5
Consumer or non-health professional from SWEDEN reported ALKERAN problem on Feb 11, 2008. Male patient, 52 years of age, was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: leukopenia, pyrexia. ALKERAN dosage: unknown. During the same period patient was treated with METOPROLOL TARTRATE, PRIMPERAN, OMEPRAZOLE, EUSAPRIMTE, ACYCLOVIR. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5632816-8
ALKERAN problem was reported by a Pharmacist from UNITED STATES on Jan 12, 2007. Female patient, 75 years of age, was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: neutropenia, platelet count decreased. ALKERAN dosage: 2MG FIVE TIMES PER DAY. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5632818-1
Consumer or non-health professional from UNITED STATES reported ALKERAN problem on May 08, 2007. Male patient was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: heart rate irregular, pain, palpitations. ALKERAN dosage: 25MG PER DAY. During the same period patient was treated with REVLIMID, PREDNISONE, ISOSORBIDE DINITRATE. Patient recovered.

Alkeran Side Effects Report #5632819-3
ALKERAN problem was reported by a Consumer or non-health professional from UNITED STATES on July 05, 2007. Female patient, 82 years of age, was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: rash. ALKERAN dosage: unknown. During the same period patient was treated with REVLIMID. Patient recovered.

Alkeran Side Effects Report #5632820-X
Consumer or non-health professional from UNITED STATES reported ALKERAN problem on Oct 19, 2007. Male patient, 74 years of age, was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: dehydration, dizziness, vertigo, vomiting. ALKERAN dosage: unknown. Patient recovered.

Alkeran Side Effects Report #5640806-4
ALKERAN problem was reported by a Physician from JAPAN on Feb 18, 2008. Male patient, 56 years of age, weighting 114.6 lb, was diagnosed with stem cell transplant, peripheral blood stem cell apheresis and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: acute myeloid leukaemia, autosomal chromosome anomaly. ALKERAN dosage: 200MGM2 PER DAY. During the same period patient was treated with ETOPOSIDE, VINDESINE SULPHATE, PREDNISOLONE, RANIMUSTINE. Patient was hospitalized. Patient died on 07/01/2007.

Alkeran Side Effects Report #5640807-6
Physician from JAPAN reported ALKERAN problem on Feb 14, 2008. Male patient, 62 years of age, was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: haemoptysis, hepatic neoplasm malignant. ALKERAN dosage: unknown. During the same period patient was treated with VINCRISTINE SULPHATE, ADRIACIN, DEXAMETHASONE, CYCLOPHOSPHAMIDE. Patient was hospitalized. Patient died on 10/28/2006.

Alkeran Side Effects Report #5645316-6
ALKERAN problem was reported by a Physician from JAPAN on Feb 28, 2008. Male patient, 54 years of age, weighting 123.5 lb, was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: c-reactive protein increased, cardiac failure, convulsion, hyponatraemia, inappropriate antidiuretic hormone secretion, interstitial lung disease, pneumothorax. ALKERAN dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, PREDONINE, CIPROFLOXACIN, GASTER D, DIFLUCAN, ZOVIRAX, FUROSEMIDE. Patient was hospitalized. Patient died on 08/25/2006.

Alkeran Side Effects Report #5645345-2
Physician from JAPAN reported ALKERAN problem on Feb 25, 2008. Male patient, 65 years of age, weighting 160.9 lb, was diagnosed with stem cell transplant and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: cryptogenic organising pneumonia, dyspnoea, graft versus host disease in lung, interstitial lung disease. ALKERAN dosage: 140MGM2 PER DAY. During the same period patient was treated with FLUDARA, PREDONINE, METHOTREXATE, NEUTROGIN, CYCLOSPORINE. Patient died on 08/09/2007.

Alkeran Side Effects Report #5579181-2
ALKERAN problem was reported by a Physician from JAPAN on Dec 28, 2007. Female patient, child 9 years of age, weighting 80.03 lb, was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: multi-organ failure, oral pain, pneumonia, stomatitis. ALKERAN dosage: 70MG PER DAY. During the same period patient was treated with PREDONINE, TACROLIMUS HYDRATE, CELLCEPT, FLUMARIN, MAXIPIME, MEROPEN. Patient died on 03/29/2006.

Alkeran Side Effects Report #5583033-1
Health Professional from UNITED STATES reported ALKERAN problem on Jan 02, 2008. Male patient, 63 years of age, was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: disease progression, dyspnoea, megakaryocytes abnormal, myelodysplastic syndrome, oedema peripheral, pancytopenia, plasma cells increased. ALKERAN dosage: unknown. During the same period patient was treated with REVLIMID, PREDNISONE, DEXAMETHASONE, ARANESP. Patient recovered.

Alkeran Side Effects Report #5583057-4
ALKERAN problem was reported by a Physician from JAPAN on Dec 28, 2007. Male patient, 62 years of age, was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: haemoptysis, hepatic neoplasm malignant. ALKERAN dosage: unknown. During the same period patient was treated with VINCRISTINE SULPHATE, ADRIAMYCIN PFS, DEXAMETHASONE, CYCLOPHOSPHAMIDE. Patient was hospitalized. Patient died on 10/28/2006.

Alkeran Side Effects Report #5584275-1
Physician from JAPAN reported ALKERAN problem on Dec 28, 2007. Male patient, 56 years of age, weighting 114.6 lb, was diagnosed with stem cell transplant and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: acute myeloid leukaemia, autosomal chromosome anomaly, neoplasm. ALKERAN dosage: 200MGM2 PER DAY. During the same period patient was treated with ETOPOSIDE, VINDESINE SULPHATE, PREDNISOLONE, RANIMUSTINE. Patient was hospitalized. Patient died on 07/01/2007.

Alkeran Side Effects Report #5585595-7
ALKERAN problem was reported by a Physician from JAPAN on Jan 08, 2008. Female patient, 64 years of age, weighting 121.3 lb, was diagnosed with immunosuppression and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: thrombotic microangiopathy. ALKERAN dosage: 70MGM2 PER DAY. During the same period patient was treated with FLUDARA, TACROLIMUS HYDRATE, METHOTREXATE, POLYMYXIN B SULPHATE, VANCOMYCIN HYDROCHLORIDE. Patient died on 03/19/2005.

Alkeran Side Effects Report #5587003-9
Consumer or non-health professional from CANADA reported ALKERAN problem on Jan 07, 2008. Male patient was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: blood test abnormal, platelet count decreased, red blood cell count decreased. ALKERAN dosage: 2MG PER DAY. During the same period patient was treated with PREDNISONE. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5588775-X
ALKERAN problem was reported by a Consumer or non-health professional from FRANCE on Dec 31, 2007. Male patient, 67 years of age, was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: pulmonary embolism. ALKERAN dosage: unknown. During the same period patient was treated with THALIDOMIDE, DECTANCYL. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5588783-9
Physician from JAPAN reported ALKERAN problem on Jan 10, 2008. Female patient, 26 years of age, weighting 123.5 lb, was diagnosed with immunosuppression and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: hepatic failure, pleurisy. ALKERAN dosage: 60MGM2 PER DAY. During the same period patient was treated with BUSULFAN, TACROLIMUS HYDRATE, ALOSITOL, GASTER, CRAVIT, DIFLUCAN, ZOVIRAX. Patient was hospitalized. Patient died on 04/18/2002.

Alkeran Side Effects Report #5588784-0
ALKERAN problem was reported by a Physician from JAPAN on Jan 10, 2008. Male patient, 49 years of age, weighting 366.0 lb, was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: anorexia, vomiting. ALKERAN dosage: 70MGM2 PER DAY. During the same period patient was treated with FLUDARABINE PHOSPHATE, TACROLIMUS HYDRATE, METHOTREXATE, OMEPRAL, CRAVIT, DIFLUCAN, ZOVIRAX. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5589694-5
Physician from JAPAN reported ALKERAN problem on Jan 11, 2008. Male patient, child 7 years of age, weighting 35.27 lb, was diagnosed with stem cell transplant, hepatic function abnormal and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: blood pressure decreased, cough, heart rate decreased, hepatic function abnormal, hyperbilirubinaemia, hypoxia, interstitial lung disease, oliguria, oxygen saturation decreased. ALKERAN dosage: 70MG PER DAY. During the same period patient was treated with BUSULFAN, KEITEN, FRAGMIN, KYTRIL, HYDROXYZINE, PRODIF, HYDROCORTONE. Patient was hospitalized. Patient died on 11/29/2007.

Alkeran Side Effects Report #5589724-0
ALKERAN problem was reported by a Physician from JAPAN on Jan 10, 2008. Female patient, 70 years of age, weighting 116.8 lb, was diagnosed with immunosuppression and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: jaundice, sepsis. ALKERAN dosage: 70MGM2 PER DAY. During the same period patient was treated with FLUDARABINE PHOSPHATE, TACROLIMUS HYDRATE, METHOTREXATE, GASTER, CRAVIT, DIFLUCAN, ZOVIRAX. Patient died on 09/27/2004.

Alkeran Side Effects Report #5593315-5
Physician from JAPAN reported ALKERAN problem on Jan 11, 2008. Male patient, 64 years of age, weighting 127.9 lb, was diagnosed with stem cell transplant, altered state of consciousness and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, altered state of consciousness, blood bilirubin increased, blood creatinine increased, blood urea increased, dyskinesia, renal impairment. ALKERAN dosage: unknown. During the same period patient was treated with MEROPEN, ACYCLOVIR, ALEVIATIN, THIOTEPA, DECADRON, HEPARIN. Patient was hospitalized. Patient died on 01/01/2008.

Alkeran Side Effects Report #5597590-2
ALKERAN problem was reported by a Consumer or non-health professional from FRANCE on Jan 09, 2008. Male patient, 76 years of age, was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: psoriasis, rash maculo-papular, tremor. ALKERAN dosage: unknown. During the same period patient was treated with THALIDOMIDE, CHRONOADALATE, ALDACTAZIDE, ZOLTUM, PREDNISONE. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5597594-X
Consumer or non-health professional from FRANCE reported ALKERAN problem on Jan 10, 2008. Male patient, 48 years of age, was diagnosed with parenteral nutrition and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: eczema, prurigo, purpura, rash maculo-papular, skin oedema. ALKERAN dosage: 324MG SINGLE DOSE. During the same period patient was treated with CERNEVIT, ZOVIRAX, ZOPHREN, BACTRIM, LEXOMIL, MOPRAL, SPASFON. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5604329-0
ALKERAN problem was reported by a Physician from JAPAN on Jan 25, 2008. Male patient, 64 years of age, weighting 127.9 lb, was diagnosed with stem cell transplant, altered state of consciousness and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, altered state of consciousness, blood bilirubin increased, blood creatinine increased, blood urea increased, dyskinesia, renal impairment. ALKERAN dosage: 100MG PER DAY. During the same period patient was treated with MEROPEN, ACYCLOVIR, ALEVIATIN, THIOTEPA, DECADRON, HEPARIN. Patient was hospitalized. Patient died on 01/01/2008.

Alkeran Side Effects Report #5607995-9
Physician from JAPAN reported ALKERAN problem on Jan 21, 2008. Male patient, 53 years of age, weighting 123.5 lb, was diagnosed with immunosuppression and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: gastrointestinal haemorrhage, melaena, renal failure acute, toxic encephalopathy, venoocclusive liver disease. ALKERAN dosage: 140MGM2 PER DAY. During the same period patient was treated with CYCLOSPORINE, METHYLPREDNISOLONE, ISCOTIN, LOMEFLOXACIN, NYSTATIN, URSO, ZOVIRAX. Patient was hospitalized. Patient died on 05/29/2007.

Alkeran Side Effects Report #5535810-0
ALKERAN problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 27, 2007. Male patient, 63 years of age, was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: disease progression, myelodysplastic syndrome, pancytopenia. ALKERAN dosage: unknown. During the same period patient was treated with REVLIMID, PREDNISONE, DEXAMETHASONE, ARANESP. Patient recovered.

Alkeran Side Effects Report #5535812-4
Health Professional from UNITED STATES reported ALKERAN problem on Nov 27, 2007. Female patient, 61 years of age, was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: complications of transplant surgery, interstitial lung disease, respiratory failure. ALKERAN dosage: unknown. During the same period patient was treated with REVLIMID. Patient died on 01/01/2006.

Alkeran Side Effects Report #5554275-6
ALKERAN problem was reported by a Physician from JAPAN on Dec 06, 2007. Female patient, 62 years of age, weighting 121.3 lb, was diagnosed with stem cell transplant and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: febrile neutropenia, sepsis. ALKERAN dosage: 186MG PER DAY. During the same period patient was treated with CYCLOPHOSPHAMIDE, VEPESID, DEXAMETHASONE PHOSPHATE, NEUTROGIN, KYTRIL, LASIX, MEROPEN. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5557603-0
Physician from JAPAN reported ALKERAN problem on Dec 14, 2007. Female patient, 62 years of age, weighting 121.3 lb, was diagnosed with stem cell transplant and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: febrile neutropenia, sepsis. ALKERAN dosage: 186MG PER DAY. During the same period patient was treated with CYCLOPHOSPHAMIDE, VEPESID, DEXAMETHASONE PHOSPHATE, NEUTROGIN, KYTRIL, LASIX, MEROPEN. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5576543-4
ALKERAN problem was reported by a Physician from JAPAN on Dec 27, 2007. Female patient, 53 years of age, weighting 119.0 lb, was diagnosed with stem cell transplant, immunosuppression and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: pseudomembranous colitis, pyrexia. ALKERAN dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, MAXIPIME, NEUTROGIN, CYCLOSPORINE, URSO, MUCOSTA, DIFLUCAN. Patient recovered.

Alkeran Side Effects Report #5579975-3
Consumer or non-health professional from UNITED KINGDOM reported ALKERAN problem on Dec 21, 2007. Female patient, 83 years of age, was diagnosed with sarcoma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: amputation, soft tissue necrosis. ALKERAN dosage: 1 MG/KG. During the same period patient was treated with TUMOR NECROSIS FACTORECTION, HEPARIN, PROTAMINE SULPHATE. Patient was hospitalized and became disabled. Patient recovered.

Alkeran Side Effects Report #5505311-4
ALKERAN problem was reported by a Physician from JAPAN on Oct 29, 2007. Male patient, 77 years of age, weighting 94.80 lb, was diagnosed with multiple myeloma, osteoporosis, gastritis, supraventricular tachycardia, angina pectoris, hyperlipidaemia, benign prostatic hyperplasia, lumbar vertebral fracture and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: anaemia, cystitis haemorrhagic. ALKERAN dosage: 4MG PER DAY. During the same period patient was treated with PREDONINE, PRIMOBOLAN, ZANTAC, DIGOXIN, AMLODIPINE, PRAVASTATIN, HARNAL, MOBIC. Patient was hospitalized. Patient died on 11/09/2006.

Alkeran Side Effects Report #5505327-8
Consumer or non-health professional from ITALY reported ALKERAN problem on Oct 31, 2007. Female patient, 62 years of age, was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: ecchymosis, ileus, muscle atrophy, neuropathy peripheral, paraesthesia, petechiae. ALKERAN dosage: 150MG PER DAY. During the same period patient was treated with BORTEZOMIB, ZOLEDRONIC ACID. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5508784-6
ALKERAN problem was reported by a Physician from JAPAN on Nov 02, 2007. Male patient, child 7 years of age, was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: respiratory failure. ALKERAN dosage: unknown. Patient recovered.

Alkeran Side Effects Report #5511512-1
Physician from JAPAN reported ALKERAN problem on Nov 08, 2007. Male patient, child 7 years of age, weighting 35.27 lb, was diagnosed with stem cell transplant and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: cough, hypoxia, interstitial lung disease, pyrexia. ALKERAN dosage: 70MG PER DAY. During the same period patient was treated with BUSULFAN, KEITEN, FRAGMIN, KYTRIL, HYDROXYZINE, PRODIF, HYDROCORTONE. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5523369-3
ALKERAN problem was reported by a Physician from JAPAN on Nov 19, 2007. Female patient, 52 years of age, was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: acute myeloid leukaemia. ALKERAN dosage: 200MG PER DAY. Patient was hospitalized. Patient died.

Alkeran Side Effects Report #5523370-X
Physician from JAPAN reported ALKERAN problem on Nov 19, 2007. Male patient, 62 years of age, was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: hepatic neoplasm malignant. ALKERAN dosage: 200MG PER DAY. Patient was hospitalized. Patient died.

Alkeran Side Effects Report #5527286-4
ALKERAN problem was reported by a Physician from JAPAN on Nov 20, 2007. Female patient, 53 years of age, weighting 125.7 lb, was diagnosed with stem cell transplant and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: anorexia, blood albumin decreased, diarrhoea, febrile neutropenia. ALKERAN dosage: 150MG PER DAY. During the same period patient was treated with NEUTROGIN, KEITEN, ZOVIRAX, FUNGUARD, CARBENIN, FULCALIQ. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5477194-2
Pharmacist from JAPAN reported ALKERAN problem on Oct 01, 2007. Male patient, weighting 136.7 lb, was diagnosed with multiple myeloma, angina pectoris, gastric ulcer and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, angina pectoris, headache, interstitial lung disease, pyrexia, upper respiratory tract inflammation. ALKERAN dosage: unknown. During the same period patient was treated with ASPIRIN, RABEPRAZOLE, FRANDOL S, PREDNISOLONE. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5502930-6
ALKERAN problem was reported by a Consumer or non-health professional from FRANCE on Oct 22, 2007. Male patient, 57 years of age, was diagnosed with prophylaxis of nausea and vomiting and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: bone marrow failure, cardiac disorder, cholestasis, hepatosplenomegaly, hyperthermia, liver function test abnormal, lung neoplasm, oxygen saturation decreased, pancytopenia. ALKERAN dosage: 280MG SINGLE DOSE. During the same period patient was treated with MABTHERA, ZEVALIN, ETOPOSIDE, CYTARABINE, BICNU, KEPIVANCE, HEPARIN, ZOFRAN. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5504733-5
Consumer or non-health professional from FRANCE reported ALKERAN problem on Oct 23, 2007. Female patient was diagnosed with multiple myeloma, stem cell transplant and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: cardiac failure. ALKERAN dosage: unknown. During the same period patient was treated with VINCRISTINE, DOXORUBICIN HYDROCHLORIDE, DEXAMETHASONE, CYCLOPHOSPHAMIDE, MESNA. Patient died.

Alkeran Side Effects Report #5504742-6
ALKERAN problem was reported by a Health Professional from FRANCE on Oct 23, 2007. Female patient was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: cerebrovascular accident. ALKERAN dosage: unknown. During the same period patient was treated with THALIDOMIDE, PREDNISONE, DI CLODRONATE. Patient recovered.

Alkeran Side Effects Report #5448735-6
Pharmacist from JAPAN reported ALKERAN problem on Sept 07, 2007. Male patient, weighting 136.7 lb, was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, angina pectoris, headache, interstitial lung disease, pyrexia, upper respiratory tract inflammation. ALKERAN dosage: unknown. During the same period patient was treated with ASPIRIN, RABEPRAZOLE, FRANDOL S, PREDNISOLONE. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5451427-0
ALKERAN problem was reported by a Consumer or non-health professional from FRANCE on Sept 03, 2007. Male patient, 57 years of age, was diagnosed with prophylaxis of nausea and vomiting and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: bone marrow failure, cardiac disorder, cholestasis, hepatosplenomegaly, hyperthermia, liver function test abnormal, lung neoplasm, oxygen saturation decreased, pancytopenia. ALKERAN dosage: 280MG SINGLE DOSE. During the same period patient was treated with RITUXAN, ZEVALIN, ETOPOSIDE, CYTARABINE, BICNU, KEPIVANCE, HEPARIN, ZOFRAN. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5453880-5
Physician from JAPAN reported ALKERAN problem on Sept 13, 2007. Male patient, 43 years of age, weighting 132.3 lb, was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: melaena. ALKERAN dosage: 100MG PER DAY. During the same period patient was treated with NEUTROGIN, TACROLIMUS HYDRATE, METHOTREXATE, PREDONINE, ITRIZOLE, MUCODYNE. Patient recovered.

Alkeran Side Effects Report #5471011-2
ALKERAN problem was reported by a Consumer or non-health professional from FRANCE on Sept 17, 2007. Male patient, 76 years of age, was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: dermatitis exfoliative, eczema, impetigo, photosensitivity reaction, pruritus, skin disorder, staphylococcal sepsis, t-cell lymphoma, toxic skin eruption. ALKERAN dosage: unknown. During the same period patient was treated with ZOMETA, DEXAMETHASONE. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5418270-X
Consumer or non-health professional from FRANCE reported ALKERAN problem on Aug 08, 2007. Male patient, 76 years of age, was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: dermatitis exfoliative, eczema, impetigo, pruritus, skin disorder, staphylococcal sepsis. ALKERAN dosage: unknown. During the same period patient was treated with ZOMETA, DEXAMETHASONE. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5419431-6
ALKERAN problem was reported by a Physician from JAPAN on Aug 14, 2007. Female patient, child 10 years of age, weighting 51.15 lb, was diagnosed with stem cell transplant, dermatitis atopic, sedation, infection prophylaxis and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, bedridden, convulsion, dizziness, dysstasia, fatigue, loss of consciousness, muscular weakness, pupillary light reflex tests abnormal. ALKERAN dosage: 55MG PER DAY. During the same period patient was treated with FLUDARABINE PHOSPHATE, ZADITEN, HYDROXYZINE PAMOATE, PENTAZOCINE LACTATE, BAKTAR, DIFLUCAN, KYTRIL, HEPARIN. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5424974-5
Consumer or non-health professional from FRANCE reported ALKERAN problem on Aug 13, 2007. Male patient, 61 years of age, was diagnosed with transplant, febrile bone marrow aplasia and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: anuria, blood creatinine increased, confusional state, disorientation, febrile bone marrow aplasia, haemodialysis, oedema peripheral, oliguria. ALKERAN dosage: 200MG PER DAY. During the same period patient was treated with AMIKLIN, LASIX, CIPROFLOXACIN, ALLOPURINOL, TAZOCILLINE. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5392416-4
ALKERAN problem was reported by a Physician from JAPAN on July 17, 2007. Female patient, child 10 years of age, was diagnosed with stem cell transplant and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: convulsion, dizziness. ALKERAN dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, ZADITEN, BAKTAR, DIFLUCAN, HYDROXYZINE PAMOATE, PENTAZOCINE LACTATE. Patient was hospitalized and became disabled. Patient recovered.

Alkeran Side Effects Report #5401376-9
Physician from JAPAN reported ALKERAN problem on July 24, 2007. Female patient, child 10 years of age, weighting 51.15 lb, was diagnosed with stem cell transplant, sedation, infection prophylaxis and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, bedridden, convulsion, dizziness, dysstasia, fatigue, loss of consciousness, muscular weakness, photosensitivity reaction. ALKERAN dosage: 55MG PER DAY. During the same period patient was treated with FLUDARABINE PHOSPHATE, ZADITEN, HYDROXYZINE PAMOATE, PENTAZOCINE LACTATE, BAKTAR, DIFLUCAN, KYTRIL, HEPARIN. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5392416-4
ALKERAN problem was reported by a Physician from JAPAN on July 17, 2007. Female patient, child 10 years of age, was diagnosed with stem cell transplant and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: convulsion, dizziness. ALKERAN dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, ZADITEN, BAKTAR, DIFLUCAN, HYDROXYZINE PAMOATE, PENTAZOCINE LACTATE. Patient was hospitalized and became disabled. Patient recovered.

Alkeran Side Effects Report #5401376-9
Physician from JAPAN reported ALKERAN problem on July 24, 2007. Female patient, child 10 years of age, weighting 51.15 lb, was diagnosed with stem cell transplant, sedation, infection prophylaxis and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, bedridden, convulsion, dizziness, dysstasia, fatigue, loss of consciousness, muscular weakness, photosensitivity reaction. ALKERAN dosage: 55MG PER DAY. During the same period patient was treated with FLUDARABINE PHOSPHATE, ZADITEN, HYDROXYZINE PAMOATE, PENTAZOCINE LACTATE, BAKTAR, DIFLUCAN, KYTRIL, HEPARIN. Patient was hospitalized. Patient recovered.


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