ALTEPLASE Side Effects

6776727-3 | Blood Pressure Increased, Haemorrhage Intracranial, Incoherent
on Jun 17, 2010 Female patient from UNITED STATES , 89 years of age, was diagnosed with ischaemic stroke and was treated with Alteplase (View Usage). Patient experienced the following unwanted or unexpected effects: blood pressure increased, haemorrhage intracranial, incoherent. Alteplase dosage: 6.1 Mg Stat Iv Bolus; 55.3 Mg Stat Iv Drip.

6722859-5 | Blood Pressure Inadequately Controlled, Haemorrhage, Shock Haemorrhagic
Patient was taking Alteplase (View Usage). Patient had the following side effects: blood pressure inadequately controlled, haemorrhage, shock haemorrhagic on May 12, 2010 from UNITED STATES Additional patient health information: Male patient , 64 years of age, weighting 201.9 lb, was diagnosed with pneumothorax and. Alteplase dosage: 25 Mg Once Other. Patient was hospitalized.

6706925-6 | Angioedema, Hypotension, Rash, Urticaria
Adverse event was reported on Apr 30, 2010 by a Male patient taking Alteplase (View Usage) (Dosage: Iv) was diagnosed with ischaemic stroke and. Location: UNITED STATES , 60 years of age, After Alteplase was administered, patient had the following side effects: angioedema, hypotension, rash (What is rash?), urticaria.

6694941-2 | Muscle Haemorrhage
on Apr 15, 2010 Female patient from , 25 years of age, was diagnosed with livedo reticularis and was treated with Alteplase (View Usage). Patient experienced the following unwanted or unexpected effects: muscle haemorrhage. Alteplase dosage: 10 Mg. During the same period patient was treated with DIPYRIDAMOLE (225 Mg) (View Dipyridamole Review and Dipyridamole Label ), ASPIRIN (100 Mg) (View Aspirin Review and Aspirin Label ), PENTOXIFYLLINE (1200 Mg) (View Pentoxifylline Review and Pentoxifylline Label ), ENOXAPARIN SODIUM (120 Mg) (View Enoxaparin Sodium Review and Enoxaparin Sodium Label ), ALPROSTADIL (60 Mcg) (View Alprostadil Review and Alprostadil Label ), INTRAVENOUS IMMUNOGLOBULINS (0.5 G/kg For 5 Days Every 4 Weeks) (View Intravenous Immunoglobulins Review and Intravenous Immunoglobulins Label ), PREDNISOLONE (50 Mg) (View Prednisolone Review and Prednisolone Label ).


6656240-4 | Angioedema, Blood Pressure Systolic Increased, Body Temperature Decreased, Dysphonia, Hemiplegia, Ischaemic Stroke, Oropharyngeal Pain, Sensory Loss
on Mar 26, 2010 Male patient from UNITED STATES , weighting 240.5 lb, was diagnosed with ischaemic stroke, hypertension and was treated with Alteplase (View Usage). Patient had the following side effects: angioedema, blood pressure systolic increased, body temperature decreased, dysphonia, hemiplegia, ischaemic stroke, oropharyngeal pain, sensory loss. Alteplase dosage: 90mg Once Iv One Time Dose. During the same period patient was treated with LISINOPRIL (View Lisinopril Review and Lisinopril Label ). Patient was hospitalized.

6641570-2 | Grand Mal Convulsion, Haemoglobin Decreased, Haemorrhage, Pulmonary Haemorrhage, Vomiting
Patient was taking Alteplase (View Usage). After Alteplase was administered, patient had the following side effects: grand mal convulsion, haemoglobin decreased, haemorrhage, pulmonary haemorrhage, vomiting on Mar 17, 2010 from UNITED STATES Additional patient health information: Male patient , 58 years of age, weighting 213.2 lb, was diagnosed with cerebrovascular accident and. Alteplase dosage: 90 Mg Once Iv. During the same period patient was treated with AMLODIPINE (View Amlodipine Review and Amlodipine Label ), ASPIRIN (View Aspirin Review and Aspirin Label ), CARVEDILOL (View Carvedilol Review and Carvedilol Label ), CLONIDINE (View Clonidine Review and Clonidine Label ), LISINOPRIL (View Lisinopril Review and Lisinopril Label ), CLOPIDOGREL (View Clopidogrel Review and Clopidogrel Label ), SIMVASTATIN (View Simvastatin Review and Simvastatin Label ), FLUOXETINE (View Fluoxetine Review and Fluoxetine Label ). Patient was hospitalized.

6569027-8 | Haemorrhage, Ischaemic Stroke
Adverse event was reported on Jan 28, 2010 by a Male patient taking Alteplase (View Usage) (Dosage: 0.9 Mg/kg) was diagnosed with ischaemic stroke, cerebrovascular accident prophylaxis and. Location: , 68 years of age, Patient experienced the following unwanted or unexpected effects: haemorrhage, ischaemic stroke. During the same period patient was treated with DIPYRIDAMOLE (400 Mg) (View Dipyridamole Review and Dipyridamole Label ), ASPIRIN (100 Mg) (View Aspirin Review and Aspirin Label ), ATORVASTATIN (40 Mg) (View Atorvastatin Review and Atorvastatin Label ). Patient was hospitalized.

6531978-8 | Cardio-respiratory Arrest, Cerebral Haematoma, Shock
on Jan 07, 2010 Female patient from UNITED STATES , 22 years of age, weighting 147.9 lb, was diagnosed with pulmonary embolism (What is pulmonary embolism?), shock and was treated with Alteplase (View Usage). Patient had the following side effects: cardio-respiratory arrest, cerebral haematoma, shock. Alteplase dosage: 100mg Once Iv.

6427876-0 | Cellulitis, Gangrene
on Nov 04, 2009 Male patient from UNITED STATES , 70 years of age, weighting 126.3 lb, was diagnosed with ischaemic stroke and was treated with Alteplase (View Usage). After Alteplase was administered, patient had the following side effects: cellulitis (What is cellulitis?), gangrene. Alteplase dosage: 50 Mg Once Iv. Patient was hospitalized.

6383825-5 | Coma, Haemorrhage Intracranial, Mental Status Changes, No Therapeutic Response
Patient was taking Alteplase (View Usage). Patient experienced the following unwanted or unexpected effects: coma, haemorrhage intracranial, mental status changes, no therapeutic response on Sep 29, 2009 from UNITED STATES Additional patient health information: Female patient , 74 years of age, was diagnosed with deep vein thrombosis (What is deep vein thrombosis?) and. Alteplase dosage: 0.8 Mg Per Hour Iv Drip. During the same period patient was treated with HEPARIN (500 Units Per Hour Iv Drip) (View Heparin Review and Heparin Label ), FAMOTIDINE (View Famotidine Review and Famotidine Label ), LOTREL (View Lotrel Review and Lotrel Label ), HYDROCHLOROTHIAZIDE (View Hydrochlorothiazide Review and Hydrochlorothiazide Label ), LOVASTATIN (View Lovastatin Review and Lovastatin Label ), CLOPIDOGREL (View Clopidogrel Review and Clopidogrel Label ), LEVOTHYROXINE (View Levothyroxine Review and Levothyroxine Label ), ALLOPURINOL (View Allopurinol Review and Allopurinol Label ).

6338355-3 | Local Swelling, Neck Pain, Thyroid Haemorrhage, Tracheal Obstruction
Adverse event was reported on Aug 26, 2009 by a Male patient taking Alteplase (View Usage) (Dosage: 90 Mg, Unk) was diagnosed with acute myocardial infarction and. Location: GERMANY , 59 years of age, Patient had the following side effects: local swelling, neck pain, thyroid haemorrhage, tracheal obstruction. During the same period patient was treated with HEPARIN (5000 Unit, Unk) (View Heparin Review and Heparin Label ), ASPIRIN (Unk) (View Aspirin Review and Aspirin Label ), CLOPIDOGREL (Unk) (View Clopidogrel Review and Clopidogrel Label ). Patient was hospitalized.

6318081-7 | Haemorrhagic Stroke, Transient Ischaemic Attack
on Aug 20, 2009 Male patient from UNITED STATES , 86 years of age, was diagnosed with cerebrovascular accident, transient ischaemic attack and was treated with Alteplase (View Usage). After Alteplase was administered, patient had the following side effects: haemorrhagic stroke, transient ischaemic attack. Alteplase dosage: 75mg Once Iv. Patient was hospitalized.

5776103-6 | Anaemia, Haematoma, Shock Haemorrhagic
on Jun 12, 2008 Female patient from JAPAN , 87 years of age, was diagnosed with embolic stroke and was treated with Alteplase (View Usage). Patient experienced the following unwanted or unexpected effects: anaemia, haematoma, shock haemorrhagic. Alteplase dosage: 0.6 Mg/kg, Unk. During the same period patient was treated with RADICUT (60 Mg, Unk) (View Radicut Review and Radicut Label ), SODIUM CHLORIDE (200 Ml, Unk) (View Sodium Chloride Review and Sodium Chloride Label ), VEEN D (1000 Ml, Unk) (View Veen-d Review and Veen-d Label ), VEEN D (500 Ml, Unk) (View Veen-d Review and Veen-d Label ), FAMOTIDINE (20 Mg, Unk) (View Famotidine Review and Famotidine Label ), AMINO ACIDS/MULTIVITAMINS NOS (500 Ml, Unk) (View Amino Acids/multivitamins Nos Review and Amino Acids/multivitamins Nos Label ), ELECTROLYTE SOLUTION W CARBOHYDRATES NOS (500 Ml, Unk) (View Electrolyte Solution W Carbohydrates Nos Review and Electrolyte Solution W Carbohydrates Nos Label ), SOLDEM (500 Ml, Unk) (View Soldem Review and Soldem Label ). Patient was hospitalized.

5750565-2 | Blood Fibrinogen Decreased, Haematuria
Patient was taking Alteplase (View Usage). Patient had the following side effects: blood fibrinogen decreased, haematuria on May 23, 2008 from UNITED STATES Additional patient health information: Female patient , 69 years of age, was diagnosed with arterial thrombosis and. Alteplase dosage: 8.3 Mg In 1000 Ml Ns Infusion Iv. During the same period patient was treated with HYDROMORPHONE HCL (View Hydromorphone Hcl Review and Hydromorphone Hcl Label ), MORPHINE (View Morphine Review and Morphine Label ), CEFAZOLIN (View Cefazolin Review and Cefazolin Label ), HEPARIN (View Heparin Review and Heparin Label ).

5739974-5 | Haemorrhagic Stroke
Adverse event was reported on May 12, 2008 by a Male patient taking Alteplase (View Usage) (Dosage: Once) was diagnosed with cerebrovascular accident and. Location: UNITED STATES , 83 years of age, After Alteplase was administered, patient had the following side effects: haemorrhagic stroke.

5732784-4 | Agitation, Aphasia, Apnoeic Attack, Areflexia, Cerebral Haemorrhage, Cerebrovascular Accident, Coma, Hypertension
on May 07, 2008 Female patient from UNITED STATES , 80 years of age, was diagnosed with cerebrovascular accident and was treated with Alteplase (View Usage). Patient experienced the following unwanted or unexpected effects: agitation, aphasia (What is aphasia?), apnoeic attack, areflexia, cerebral haemorrhage, cerebrovascular accident, coma, hypertension. Alteplase dosage: . During the same period patient was treated with CLOPIDOGREL (Po) (View Clopidogrel Review and Clopidogrel Label ), ASPIRIN (Po) (View Aspirin Review and Aspirin Label ).

5708217-0 | Renal Infarct
on Apr 11, 2008 Male patient from JAPAN , 68 years of age, was diagnosed with cerebral artery embolism and was treated with Alteplase (View Usage). Patient had the following side effects: renal infarct. Alteplase dosage: 0.55 Mg/kg, Single. During the same period patient was treated with RADICUT (30 Mg, Unk) (View Radicut Review and Radicut Label ), ZANTAC (View Zantac Review and Zantac Label ), HEPARIN (View Heparin Review and Heparin Label ), UNASYN (View Unasyn Review and Unasyn Label ), NICARDIPINE HYDROCHLORIDE (View Nicardipine Hydrochloride Review and Nicardipine Hydrochloride Label ). Patient was hospitalized.

5682751-4 | Cerebral Haemorrhage, Convulsion, Electroencephalogram Abnormal, Ill-defined Disorder, Respiratory Failure
Patient was taking Alteplase (View Usage). After Alteplase was administered, patient had the following side effects: cerebral haemorrhage, convulsion, electroencephalogram abnormal, ill-defined disorder, respiratory failure on Mar 26, 2008 from UNITED STATES Additional patient health information: Female patient , 44 years of age, weighting 112.4 lb, was diagnosed with cerebrovascular accident and. Alteplase dosage: 47mg Once Iv. During the same period patient was treated with NAPROXEN (View Naproxen Review and Naproxen Label ), ACETAMINOPHEN (View Acetaminophen Review and Acetaminophen Label ), CEPHALEXIN (View Cephalexin Review and Cephalexin Label ).

5634726-9 | Pyrexia, Rash
Adverse event was reported on Feb 21, 2008 by a Male patient taking Alteplase (View Usage) (Dosage: 4mg Once Other) . Location: UNITED STATES , 67 years of age, Patient experienced the following unwanted or unexpected effects: pyrexia, rash (What is rash?). Patient was hospitalized.

4832685-X | Cerebral Haemorrhage, Headache, Subarachnoid Haemorrhage
on Nov 17, 2005 Female patient from UNITED STATES , 63 years of age, was diagnosed with ischaemic stroke and was treated with Alteplase (View Usage). Patient had the following side effects: cerebral haemorrhage, headache (What is headache?), subarachnoid haemorrhage. Alteplase dosage: 0.9mg/kg Over 60 Minutes Once Iv Drip (one Time Only Dose). During the same period patient was treated with PHENYTOIN (View Phenytoin Review and Phenytoin Label ). Patient was hospitalized.

4808357-4 | Hyperhidrosis, Hypotension, Tachycardia
on Oct 20, 2005 Male patient from UNITED STATES , 61 years of age, was diagnosed with cerebrovascular accident and was treated with Alteplase (View Usage). After Alteplase was administered, patient had the following side effects: hyperhidrosis, hypotension, tachycardia. Alteplase dosage: 47mg (90min) Once. During the same period patient was treated with ASPIRIN (View Aspirin Review and Aspirin Label ), RANITIDINE (View Ranitidine Review and Ranitidine Label ), SIMVASTATIN (View Simvastatin Review and Simvastatin Label ), CITALOPRAM (View Citalopram Review and Citalopram Label ), LISINOPRIL (View Lisinopril Review and Lisinopril Label ).

4807316-5 | Dyspnoea, Hyperhidrosis, Hypertension, Tachycardia
Patient was taking Alteplase (View Usage). Patient experienced the following unwanted or unexpected effects: dyspnoea, hyperhidrosis, hypertension, tachycardia on Oct 20, 2005 from UNITED STATES Additional patient health information: Male patient , 57 years of age, was diagnosed with catheter related complication and. Alteplase dosage: 2mg Once 10am. During the same period patient was treated with TYLENOL W/ CODEINE NO. 3 (View Tylenol W/ Codeine No. 3 Review and Tylenol W/ Codeine No. 3 Label ), ASPIRIN (View Aspirin Review and Aspirin Label ), LASIX (View Lasix Review and Lasix Label ), INSULIN (View Insulin Review and Insulin Label ), FLAGYL (View Flagyl Review and Flagyl Label ), OMEPRAZOLE (View Omeprazole Review and Omeprazole Label ).

4801797-9 | Haematoma, Small Intestinal Haemorrhage
Adverse event was reported on Oct 14, 2005 by a Female patient taking Alteplase (View Usage) (Dosage: 100 Mg Iv) was diagnosed with pulmonary embolism (What is pulmonary embolism?) and. Location: UNITED STATES , weighting 160.9 lb, Patient had the following side effects: haematoma, small intestinal haemorrhage. Patient was hospitalized.

4776923-0 | Cerebral Haemorrhage, Dizziness, Gait Disturbance, Nausea
on Sep 22, 2005 Female patient from UNITED STATES , 80 years of age, weighting 130.5 lb, was diagnosed with peripheral occlusive disease and was treated with Alteplase (View Usage). After Alteplase was administered, patient had the following side effects: cerebral haemorrhage, dizziness (What is dizziness?), gait disturbance, nausea (What is nausea?). Alteplase dosage: 1mg/hr X 12 Hours, 0.5 Mg/hr Iv Drip. During the same period patient was treated with HEPARIN (View Heparin Review and Heparin Label ).

4727557-5 | Abdominal Pain, Contusion, Haemorrhage, Screaming
on Jul 27, 2005 Female patient from UNITED STATES , 28 years of age, weighting 121.3 lb, was diagnosed with haemorrhage and was treated with Alteplase (View Usage). Patient experienced the following unwanted or unexpected effects: abdominal pain (What is abdominal pain?), contusion, haemorrhage, screaming. Alteplase dosage: 100 Mg Once Pr. During the same period patient was treated with WARFARIN (Po) (View Warfarin Review and Warfarin Label ). Patient was hospitalized.