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Amilorid Side Effects

Common Amilorid Side Effects

The most commonly reported Amilorid side effects (click to view or check a box to report):

Hyperkalaemia (11)
Renal Failure Acute (10)
Hyponatraemia (8)
Hypokalaemia (8)
Oedema Peripheral (6)
Asthenia (5)
Blood Creatinine Increased (5)
Cardiac Arrest (5)
Hypotension (4)
Diarrhoea (4)
Abdominal Pain (4)
Dyspnoea (3)
Dizziness (3)
Malaise (3)
Renal Failure Chronic (3)
Pneumoperitoneum (2)
Presyncope (2)
Pain (2)
Melaena (2)
Pleural Effusion (2)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

Amilorid Side Effects Reported to FDA

The following Amilorid reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.


The appearance of Amilorid on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.
Heart Rate Decreased, Dizziness
on Nov 05, 2013 Female from US , 70 years of age, was diagnosed with and was treated with Amiloride Hydrochloride And Hydrochlorothiazide Tablets, Usp. Directly after, patient experienced the unwanted or unexpected Amilorid side effects: heart rate decreased, dizziness. Amiloride Hydrochloride And Hydrochlorothiazide Tablets, Usp dosage: N/A.

Pulmonary Oedema, Shock
Patient was taking Amiloride/hydrochlorothiazide. Patient felt the following Amilorid side effects: pulmonary oedema, shock on Sep 30, 2013 from DE Additional patient health information: Female , 74 years of age, . Amiloride/hydrochlorothiazide dosage: 1 Df, Single.

Hyperkalaemia, Pulmonary Embolism, Renal Impairment
Adverse event was reported on Mar 21, 2013 by a Male taking Amiloride (Dosage: 2 Tab Every Day Po) was diagnosed with and. Location: US , 64 years of age, weighting 272.5 lb, After Amilorid was administered, patient encountered several Amilorid side effects: hyperkalaemia, pulmonary embolism, renal impairment.
Multiple concurrent drugs taken:
  • Lisinopril (1 Tab Every Day Po)
Patient was hospitalized.

Urinary Retention, Weight Increased, Abdominal Distension, Oedema Peripheral
on Nov 15, 2012 Female from US , 55 years of age, weighting 200.0 lb, was treated with Amiloride Hcl. Directly after, patient experienced the unwanted or unexpected Amilorid side effects: urinary retention, weight increased, abdominal distension, oedema peripheral. Amiloride Hcl dosage: N/A.
Associated medications used:
  • Amiloride Hydrochloride
  • Thyroid



Dysgeusia, Weight Decreased
on Sep 05, 2012 Male from US , 66 years of age, weighting 185.0 lb, was diagnosed with and was treated with Amiloride. Patient felt the following Amilorid side effects: dysgeusia, weight decreased. Amiloride dosage: N/A.

Transient Ischaemic Attack, Aphasia, Facial Paresis
Patient was taking Amiloride Hydrochloride. After Amilorid was administered, patient encountered several Amilorid side effects: transient ischaemic attack, aphasia, facial paresis on May 21, 2012 from GERMANY Additional patient health information: Female , weighting 149.9 lb, . Amiloride Hydrochloride dosage: N/A.
Multiple concurrent drugs taken:
  • Bisoprolol Fumarate (5 Mg)
  • Amitriptyline Hcl
  • Memantine Hcl (5 Mg)
  • Pantoprazole
  • Tensoflux
  • Simvastatin (40 Mg)
  • Dytide
Patient was hospitalized.

Duodenal Ulcer Perforation, Abdominal Pain, Pneumoperitoneum
Adverse event was reported on May 11, 2012 by a Male taking Amiloride Hcl (Dosage: N/A) . Location: , 82 years of age, Directly after, patient experienced the unwanted or unexpected Amilorid side effects: duodenal ulcer perforation, abdominal pain, pneumoperitoneum.
Associated medications used:
  • Bendroflumethiazide (bendroflumethiazide)
  • Calceos (lekovit Ca)
  • Acetaminophen W/ Codeine
  • Warfarin Sodium
  • Amlodipine
  • Digoxin
  • Alendronic Acid (alendronic Acid) (10 Mg (70 Mg, 1 In 1 Wk), Oral)
Patient was hospitalized.

Pneumoperitoneum, Abdominal Pain, Duodenal Ulcer Perforation
on May 11, 2012 Male from UNITED KINGDOM , 82 years of age, was treated with Amiloride Hydrochloride. Patient felt the following Amilorid side effects: pneumoperitoneum, abdominal pain, duodenal ulcer perforation. Amiloride Hydrochloride dosage: N/A.
Multiple prescriptions taken:
  • Amlodipine Besylate
  • Warfarin Sodium
  • Alendronate Sodium (70 Mg, Qw)
  • Bendroflumethiazide
  • Calceos
  • Acetaminophen And Codeine Phosphate
  • Digoxin
Patient was hospitalized.

Diarrhoea, Hyperhidrosis, Hypoaesthesia Oral, Feeling Abnormal, Nausea, Communication Disorder
on May 03, 2012 Female from HUNGARY , 41 years of age, weighting 242.5 lb, was diagnosed with and was treated with Amiloride. After Amilorid was administered, patient encountered several Amilorid side effects: diarrhoea, hyperhidrosis, hypoaesthesia oral, feeling abnormal, nausea, communication disorder. Amiloride dosage: Unk.
Multiple concurrent drugs taken:
  • Letrox (Unk)
  • Lyrica (75 Mg, 2x/day)
  • Lyrica (75 Mg, 2x/day)
  • Lyrica (150 Mg, 2x/day)


Sclerosing Encapsulating Peritonitis, Hyperkalaemia, Ascites, Gynaecomastia
Patient was taking Amiloride Hydrochloride. Directly after, patient experienced the unwanted or unexpected Amilorid side effects: sclerosing encapsulating peritonitis, hyperkalaemia, ascites, gynaecomastia on Apr 24, 2012 from UNITED KINGDOM Additional patient health information: Male , 48 years of age, . Amiloride Hydrochloride dosage: N/A.
Associated medications used:
  • Propranolol Hydrochloride (40 Mg / Twice Per Day)
  • Spironolactone
  • Atenolol
Patient was hospitalized.

Hypokalaemia, Hyponatraemia
Adverse event was reported on Apr 12, 2012 by a Female taking Amiloride Hcl And Hydrochlorothiazide (Dosage: N/A) . Location: SWEDEN , 75 years of age, Patient felt the following Amilorid side effects: hypokalaemia, hyponatraemia.
Multiple prescriptions taken:
  • Ibuprofen
  • Citalopram Hydrobromide


Renal Failure Chronic
on Apr 04, 2012 Female from SWITZERLAND , 75 years of age, was treated with Amiloride Hcl And Hydrochlorothiazide. After Amilorid was administered, patient encountered several Amilorid side effects: renal failure chronic. Amiloride Hcl And Hydrochlorothiazide dosage: 1 Df, Uid/qd.
Multiple concurrent drugs taken:
  • Marcumar (3 Mg, Prn)
  • Prograf (1 Df, Uid/qd)
  • Prograf (6 Mg, Uid/qd)
  • Floxapen (2 G, Tid)
  • Prograf (3 Mg, Uid/qd)
  • Allopurinol (Unk Mg, Uid/qd)
  • Prograf (3.5 Mg, Uid/qd)
  • Zestril (30 Mg, Uid/qd)


Rash, Dyspnoea, Periorbital Oedema, Pericardial Effusion, Diarrhoea, Disease Progression
on Dec 16, 2008 Female from UNITED STATES , 77 years of age, weighting 117.1 lb, was treated with Amiloride (amiloride). Directly after, patient experienced the unwanted or unexpected Amilorid side effects: rash, dyspnoea, periorbital oedema, pericardial effusion, diarrhoea, disease progression. Amiloride (amiloride) dosage: N/A.
Associated medications used:
  • Zyrtec
  • Pravachol
  • Gleevec (400 Mg, Bid, Oral)
  • Gleevec (400 Mg, Bid, Oral)
  • Ambien
  • Fosamax


Fatigue, Rash Maculo-papular, Diarrhoea, Pruritus, Loss Of Consciousness, Dyspnoea
Patient was taking Amiloride Hcl And Hydrochlorothiazide. Patient felt the following Amilorid side effects: fatigue, rash maculo-papular, diarrhoea, pruritus, loss of consciousness, dyspnoea on Feb 28, 2012 from SERBIA Additional patient health information: Female , 61 years of age, weighting 149.9 lb, . Amiloride Hcl And Hydrochlorothiazide dosage: N/A.
Multiple prescriptions taken:
  • Spironolactone
  • Doxorubicin Hcl
  • Metoprolol Succinate
  • Cyclophosphamide


Lactic Acidosis, Renal Failure Acute, Hyponatraemia, Hypokalaemia, Constipation, Hypocalcaemia, Endocrine Disorder
Adverse event was reported on Feb 03, 2012 by a Female taking Amiloride Hcl And Hydrochlorothiazide (Dosage: 1 Df = Hydrochlorothiazide 5mg+ Amiloride 50mg) . Location: GERMANY , 36 years of age, weighting 108.0 lb, After Amilorid was administered, patient encountered several Amilorid side effects: lactic acidosis, renal failure acute, hyponatraemia, hypokalaemia, constipation, hypocalcaemia, endocrine disorder.
Multiple concurrent drugs taken:
  • Bisacodyl
  • Metformin Hcl
  • Levothyroxine Sodium
  • Metformin Hcl
Patient was hospitalized.

Pulmonary Embolism, Post-traumatic Stress Disorder, Mental Disorder, Emotional Distress, Fear, Musculoskeletal Chest Pain, Anxiety
on Feb 03, 2012 Female from UNITED STATES , 24 years of age, weighting 199.0 lb, was treated with Amiloride Hydrochloride. Directly after, patient experienced the unwanted or unexpected Amilorid side effects: pulmonary embolism, post-traumatic stress disorder, mental disorder, emotional distress, fear, musculoskeletal chest pain, anxiety. Amiloride Hydrochloride dosage: Unk.
Associated medications used:
  • Motrin (800 Mg, Unk)
  • Lisinopril (Unk)
  • Ascorbic Acid (Unk)
  • Percocet (Unk)
  • Yasmin (Unk)
  • Morphine Sulfate (Unk)
Patient was hospitalized.

Lactic Acidosis, Hypokalaemia, Renal Failure Acute, Hyponatraemia
on Jan 23, 2012 Female from ITALY , 36 years of age, weighting 108.0 lb, was diagnosed with and was treated with Amiloride Hcl And Hydrochlorothiazide. Patient felt the following Amilorid side effects: lactic acidosis, hypokalaemia, renal failure acute, hyponatraemia. Amiloride Hcl And Hydrochlorothiazide dosage: 5/50mg Day.
Multiple prescriptions taken:
  • Bisacodyl
  • Levothyroxine Sodium (100 Microg/day)
  • Metformin Hcl (1000mg Three Times Daily)
Patient was hospitalized.

Gastroenteritis, Febrile Neutropenia
Patient was taking Amiloride. After Amilorid was administered, patient encountered several Amilorid side effects: gastroenteritis, febrile neutropenia on Jan 23, 2012 from BRAZIL Additional patient health information: Male , 79 years of age, weighting 172.2 lb, was diagnosed with and. Amiloride dosage: 5 Mg, 1x/day.
Multiple concurrent drugs taken:
  • Prednisone Tab (5 Mg, Twice Daily)
  • Calcium (500 Mg, 1x/day)
  • Zoledronic Acid (3 Mg, Monthly)
  • Sunitinib Malate (37.5 Mg, Daily)
  • Hydrochlorothiazide (50 Mg, 1x/day)
  • Dipyrone Inj (40 Drops, As Needed)
Patient was hospitalized.

Abdominal Pain, Fluid Retention
Adverse event was reported on Dec 15, 2011 by a Male taking Amiloride Hcl And Hydrochlorothiazide (Dosage: N/A) was diagnosed with and. Location: SPAIN , 72 years of age, weighting 176.4 lb, Directly after, patient experienced the unwanted or unexpected Amilorid side effects: abdominal pain, fluid retention.
Associated medications used:
  • Dutasteride/tamsulosin Hydrochloride


Cardiac Arrest, Hyperkalaemia, Renal Injury
on Dec 02, 2011 Male from AUSTRIA , 73 years of age, was treated with Amiloride Hcl And Hydrochlorothiazide. Patient felt the following Amilorid side effects: cardiac arrest, hyperkalaemia, renal injury. Amiloride Hcl And Hydrochlorothiazide dosage: 50/5mg Once Daily.
Multiple prescriptions taken:
  • Furosemide (30 Mg, Qd)
  • Spironolactone (100 Mg, Qd)
  • Enalapril Maleate (10 Mg, Qd)


Blood Creatinine Increased, Azotaemia, Sepsis, Renal Failure Acute
on Dec 06, 2011 Male from INDIA , 61 years of age, was treated with Amiloride Hydrochloride. After Amilorid was administered, patient encountered several Amilorid side effects: blood creatinine increased, azotaemia, sepsis, renal failure acute. Amiloride Hydrochloride dosage: 40 Mg.
Multiple concurrent drugs taken:
  • Furosemide (80 Mg)
  • Arteether (150 Mg)
  • Torsemide (40 Mg)
  • Cefotaxime (2 G)
  • Caspofungin Acetate (50 Mg)
  • Tazobactam
  • Meropenem
  • Atenolol (75 Mg)
Patient was hospitalized.

Renal Failure Chronic, Cardiac Arrest, Hyperkalaemia
Patient was taking Amiloride Hcl And Hydrochlorothiazide. Directly after, patient experienced the unwanted or unexpected Amilorid side effects: renal failure chronic, cardiac arrest, hyperkalaemia on Nov 25, 2011 from AUSTRIA Additional patient health information: Male , 73 years of age, . Amiloride Hcl And Hydrochlorothiazide dosage: 50/5mg Once Daily.
Associated medications used:
  • Enalapril Maleate
  • Spironolactone
  • Furosemide


Palmar-plantar Erythrodysaesthesia Syndrome, Asthenia, Off Label Use, Lower Respiratory Tract Infection, Toxicity To Various Agents, Cardiac Failure Congestive
Adverse event was reported on Nov 25, 2011 by a Female taking Amilorid/hctz (amiloride Hydrochloride, Hydrochlorothiazide) (Dosage: N/A) . Location: SOUTH AFRICA , 59 years of age, weighting 119.0 lb, Patient felt the following Amilorid side effects: palmar-plantar erythrodysaesthesia syndrome, asthenia, off label use, lower respiratory tract infection, toxicity to various agents, cardiac failure congestive.
Multiple prescriptions taken:
  • Spiractin (spironolactone)
  • Analgesics (analgesics)
  • Asthavent (salbutamol)
  • Erlotinib Hydrochloride (See Image)
  • Erlotinib Hydrochloride (See Image)
  • Erlotinib Hydrochloride (See Image)
  • Erlotinib Hydrochloride (See Image)
  • Erlotinib Hydrochloride (See Image)
Patient was hospitalized.

Hyponatraemia, Renal Failure Acute, Depressed Level Of Consciousness, Urinary Tract Infection, Hypochromic Anaemia, Dehydration, Fall, Renal Failure Chronic
on Nov 18, 2011 Female from UNITED STATES , 72 years of age, weighting 105.8 lb, was treated with Amiloride Hydrochloride. After Amilorid was administered, patient encountered several Amilorid side effects: hyponatraemia, renal failure acute, depressed level of consciousness, urinary tract infection, hypochromic anaemia, dehydration, fall, renal failure chronic. Amiloride Hydrochloride dosage: N/A.
Multiple concurrent drugs taken:
  • Hydrochlorothiazide (50 Mg;qd)
  • Bisoprolol Fumarate
  • Lisinopril
  • Levothyroxine Sodium
Patient was hospitalized.

Haemoptysis, Alanine Aminotransferase Increased, Thrombocytopenia, Hypofibrinogenaemia, Asthenia, Oedema Peripheral, Constipation, Hypoalbuminaemia, Leukopenia
on Nov 29, 2011 Female from ITALY , 48 years of age, was treated with Amiloride Hcl And Hydrochlorothiazide. Directly after, patient experienced the unwanted or unexpected Amilorid side effects: haemoptysis, alanine aminotransferase increased, thrombocytopenia, hypofibrinogenaemia, asthenia, oedema peripheral, constipation, hypoalbuminaemia, leukopenia. Amiloride Hcl And Hydrochlorothiazide dosage: 1 Df, 1x/day.
Associated medications used:
  • Calcium Carbonate (1000 Mg, Unk)
  • Colecalciferol (1 Df, Every 2 Weeks)
  • Crizotinib (200 Mg, 2x/day (every 12 Hours))
  • Ranitidine (150 Mg, Every 12 Hours)
  • Fentanyl Citrate (25 Mcg/h Every 72 Hours)
  • Levetiracetam (500 Mg, Every 12 Hours)
  • Macrogol (17.5 G, 2x/day)
Patient was hospitalized.

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    Safety Alerts, Active Ingredients, Usage Information

    Alternative AMILORID Names:GUNA-DIUR

    Active Ingredient: AMILORIDE

    More About Amilorid

    Side Effects reported to FDA: 64

    Amilorid safety alerts: No

    Reported deaths: 3

    Reported hospitalizations: 15

    Latest Amilorid clinical trials

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