Arava Safety Questions, Arava Answers
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Arava Safety Reports
Total Arava reports: 492.Arava FDA safety alerts: 2003 .
Reported deaths: 61 Reported hospitalizations: 238.
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Reported Arava Side Effects: alanine aminotransferase increased, aspartate aminotransferase increased, diarrhoea, blood alkaline phosphatase increased, pyrexia, gamma-glutamyltransferase increased, blood lactate dehydrogenase increased, vomiting, hepatic function abnormal, myocardial infarction, alopecia.
Arava Usage.
Showing 1-50 of 492 Next >
Arava Side Effects Report #5239457-5Pharmacist from NETHERLANDS reported ARAVA problem on Feb 09, 2007. Female patient, 65 years of age, weighting 136.7 lb, was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, hepatic function abnormal. ARAVA dosage: unknown. During the same period patient was treated with OMEPRAZOLE, PREDNISOLONE, ACTONEL, CALCIUM CARBONATE W. Patient was hospitalized. Patient recovered.
Arava Side Effects Report #5241451-5
ARAVA problem was reported by a Physician from FRANCE on Feb 13, 2007. Female patient, 36 years of age, was diagnosed with polyarthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: areflexia, autonomic nervous system imbalance, fall, fracture, hypoaesthesia, orthostatic hypotension, paraesthesia, peripheral sensory neuropathy. ARAVA dosage: unknown. During the same period patient was treated with NSAID, CORTICOSTEROIDS. Patient was hospitalized. Patient recovered.
Arava Side Effects Report #5242493-6
Physician from SOUTH AFRICA reported ARAVA problem on Feb 07, 2007. Female patient, 64 years of age, was diagnosed with rheumatoid arthritis, menopause, hypertension and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: anaemia megaloblastic, mycobacterial infection, myelofibrosis. ARAVA dosage: unknown. During the same period patient was treated with METHOTREXATE, ACTIVELLE, DYNACIRC, FOLIC ACID, CELEBREX, NEXIAM. Patient recovered.
Arava Side Effects Report #5242494-8
ARAVA problem was reported by a Consumer or non-health professional from on Feb 16, 2007. Female patient, 75 years of age, weighting 180.8 lb, was diagnosed with rheumatoid arthritis, dental care and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, gamma-glutamyltransferase increased, hepatitis, mixed hepatocellular-cholestatic injury. ARAVA dosage: unknown. During the same period patient was treated with BIRODOGYL, ACETAMINOPHEN W, ALODONT, ACTONEL, CORTANCYL, LASILIX, ZANIDIP, ACUITEL. Patient was hospitalized. Patient recovered.
Arava Side Effects Report #5243951-0
Physician from UNITED STATES reported ARAVA problem on Feb 20, 2007. Female patient, weighting 212.0 lb, was diagnosed with rheumatoid arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: acidosis, dehydration, pancreatitis acute, renal failure. ARAVA dosage: 20MG DAILY PO. Patient was hospitalized. Patient recovered.
Arava Side Effects Report #5245098-6
ARAVA problem was reported by a Physician from FRANCE on Feb 16, 2007. Female patient, 56 years of age, was diagnosed with rheumatoid arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: cutaneous lupus erythematosus, erythema annulare, rash macular, rash maculo-papular, rheumatoid arthritis. ARAVA dosage: unknown. During the same period patient was treated with NEURONTIN, BIPRETERAX, COVERSYL, ZOLOFT, OMEPRAZOLE, LEXOMIL, DURAGESIC, ABUFENE. Patient recovered.
Arava Side Effects Report #5246641-3
Physician from BELGIUM reported ARAVA problem on Feb 15, 2007. Female patient, 38 years of age, was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: nephritis interstitial, renal failure acute. ARAVA dosage: unknown. During the same period patient was treated with CORTICOSTEROIDS, LEDERTREXATE. Patient was hospitalized. Patient recovered.
Arava Side Effects Report #5246642-5
ARAVA problem was reported by a Pharmacist from UNITED KINGDOM on Feb 16, 2007. Male patient was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: confusional state, creutzfeldt-jakob disease, diarrhoea, electroencephalogram abnormal, pyrexia. ARAVA dosage: unknown. Patient recovered.
Arava Side Effects Report #5247676-7
Physician from AUSTRALIA reported ARAVA problem on Feb 07, 2007. Female patient, 52 years of age, was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: liver function test abnormal. ARAVA dosage: unknown. During the same period patient was treated with METHOTREXATE, CELECOXIB, PREDNISONE, AVAPRO, VENLAFAXINE, OXYCODONE, CHOLECALCIFEROL. Patient recovered.
Arava Side Effects Report #5247677-9
ARAVA problem was reported by a Physician from CZECH REPUBLIC on Feb 19, 2007. Female patient, 65 years of age, was diagnosed with rheumatoid arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: anaemia, erysipelas, febrile neutropenia, hypoalbuminaemia, hypokalaemia, infected skin ulcer, leukopenia, pancytopenia, pyrexia. ARAVA dosage: unknown. During the same period patient was treated with METHOTREXATE, HARTIL, MODURETIC, BETALOC, ALENDROS, IRON PREPARATIONS. Patient was hospitalized. Patient recovered.
Arava Side Effects Report #5247678-0
Physician from SOUTH AFRICA reported ARAVA problem on Feb 19, 2007. Female patient, 64 years of age, was diagnosed with rheumatoid arthritis, menopause, hypertension and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: anaemia megaloblastic, mycobacterial infection, myelofibrosis. ARAVA dosage: unknown. During the same period patient was treated with METHOTREXATE, ACTIVELLE, DYNACIRC, FOLIC ACID, CELEBREX, NEXIAM. Patient recovered.
Arava Side Effects Report #5252611-1
ARAVA problem was reported by a Pharmacist from UNITED STATES on Feb 27, 2007. Female patient, 31 years of age, was diagnosed with rheumatoid arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: hypertensive crisis. ARAVA dosage: unknown. During the same period patient was treated with PREDNISONE. Patient was hospitalized. Patient recovered.
Arava Side Effects Report #5252545-2
Consumer or non-health professional from reported ARAVA problem on Feb 19, 2007. Female patient, 75 years of age, was diagnosed with rheumatoid arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: condition aggravated, varicose ulceration. ARAVA dosage: unknown. During the same period patient was treated with CORTANCYL. Patient was hospitalized. Patient recovered.
Arava Side Effects Report #5254075-0
ARAVA problem was reported by a Physician from FRANCE on Feb 23, 2007. Female patient, 17 years of age, weighting 132.3 lb, was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: headache, pyrexia. ARAVA dosage: unknown. Patient was hospitalized. Patient recovered.
Arava Side Effects Report #5255096-4
Physician from FRANCE reported ARAVA problem on Feb 16, 2007. Female patient, 30 years of age, was diagnosed with rheumatoid arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: no adverse effect. ARAVA dosage: unknown. Patient recovered.
Arava Side Effects Report #5255097-6
ARAVA problem was reported by a Consumer or non-health professional from on Feb 20, 2007. Female patient, 32 years of age, weighting 119.9 lb, was diagnosed with rheumatoid arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: aggression. ARAVA dosage: unknown. During the same period patient was treated with FOLIC ACID, METHOTREXATE. Patient recovered.
Arava Side Effects Report #5255098-8
Physician from AUSTRALIA reported ARAVA problem on Feb 23, 2007. Female patient, 75 years of age, was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: retinal detachment. ARAVA dosage: unknown. Patient recovered.
Arava Side Effects Report #5256306-X
ARAVA problem was reported by a Physician from ROMANIA on Feb 26, 2007. Female patient, 58 years of age, was diagnosed with rheumatoid arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: myocardial infarction. ARAVA dosage: unknown. During the same period patient was treated with PIROXICAM. Patient died on 01/01/2007.
Arava Side Effects Report #5258576-0
Physician from SPAIN reported ARAVA problem on Mar 01, 2007. Female patient, 65 years of age, was diagnosed with rheumatoid arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: bone marrow failure, mucosal inflammation. ARAVA dosage: unknown. During the same period patient was treated with METHOTREXATE. Patient was hospitalized. Patient recovered.
Arava Side Effects Report #5258580-2
ARAVA problem was reported by a Consumer or non-health professional from on Mar 05, 2007. Male patient, 81 years of age, was diagnosed with rheumatoid arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: hodgkin's disease, lymphadenopathy. ARAVA dosage: unknown. During the same period patient was treated with HUMIRA, CATAPRESAN, COZAAR, LASIX, ANGORON, SINTROM, PREZOLON. Patient recovered.
Arava Side Effects Report #5258581-4
Physician from SPAIN reported ARAVA problem on Feb 26, 2007. Female patient, 28 years of age, weighting 132.3 lb, was diagnosed with rheumatoid arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: pregnancy. ARAVA dosage: unknown. During the same period patient was treated with CORTICOSTEROIDS. Patient recovered.
Arava Side Effects Report #5259846-2
ARAVA problem was reported by a Physician from JAPAN on Mar 06, 2007. Female patient, 55 years of age, weighting 97.00 lb, was diagnosed with rheumatoid arthritis, osteoporosis, gastritis prophylaxis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, blood lactate dehydrogenase increased, gamma-glutamyltransferase increased. ARAVA dosage: unknown. During the same period patient was treated with PREDONINE, BONALON, GASTER D, METHOTREXATE. Patient recovered.
Arava Side Effects Report #5259848-6
Physician from SOUTH AFRICA reported ARAVA problem on Mar 06, 2007. Female patient, 64 years of age, was diagnosed with rheumatoid arthritis, menopause, hypertension and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: anaemia megaloblastic, mycobacterial infection, myelofibrosis. ARAVA dosage: unknown. During the same period patient was treated with METHOTREXATE, ACTIVELLE, DYNACIRC, FOLIC ACID, CELEBREX, NEXIAM. Patient recovered.
Arava Side Effects Report #5262508-9
ARAVA problem was reported by a Pharmacist from JAPAN on Mar 07, 2007. Male patient, 73 years of age, weighting 160.9 lb, was diagnosed with rheumatoid arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: bladder cancer recurrent. ARAVA dosage: unknown. During the same period patient was treated with MOBIC, PROMAC, OMEPRAL, PREDONINE, RHEUMATREX. Patient recovered.
Arava Side Effects Report #5262509-0
Physician from SPAIN reported ARAVA problem on Mar 05, 2007. Male patient was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: dysuria, penile pain, penis disorder. ARAVA dosage: unknown. During the same period patient was treated with ENBREL. Patient recovered.
Arava Side Effects Report #5263652-2
ARAVA problem was reported by a Physician from BELGIUM on Mar 05, 2007. Female patient, 38 years of age, weighting 222.7 lb, was diagnosed with rheumatoid arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: haemodialysis, influenza, nephritis interstitial, pyelonephritis, renal failure acute. ARAVA dosage: unknown. During the same period patient was treated with METHYLPREDNISOLONE, LEDERTREXATE, ELTHYRONE. Patient was hospitalized. Patient recovered.
Arava Side Effects Report #5266291-2
Pharmacist from JAPAN reported ARAVA problem on Mar 08, 2007. Male patient, 73 years of age, weighting 160.9 lb, was diagnosed with rheumatoid arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: bladder cancer recurrent. ARAVA dosage: unknown. During the same period patient was treated with MOBIC, PROMAC, OMEPRAL, PREDONINE, RHEUMATREX. Patient recovered.
Arava Side Effects Report #5266293-6
ARAVA problem was reported by a Consumer or non-health professional from on Mar 12, 2007. Female patient, 75 years of age, weighting 132.9 lb, was diagnosed with rheumatoid arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: acute sinusitis, anorexia, arthralgia, condition aggravated, dry mouth, fatigue, malaise, red blood cell sedimentation rate increased, sudden hearing loss. ARAVA dosage: unknown. During the same period patient was treated with CALCICHEW, RELIFEX, SULFASALAZINE. Patient recovered.
Arava Side Effects Report #5267149-5
Consumer or non-health professional from UNITED STATES reported ARAVA problem on Mar 06, 2007. Female patient was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: ill-defined disorder. ARAVA dosage: unknown. During the same period patient was treated with REMICADE. Patient died on 06/24/2005.
Arava Side Effects Report #5267152-5
ARAVA problem was reported by a Pharmacist from UNITED KINGDOM on Feb 26, 2007. Male patient was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: confusional state, creutzfeldt-jakob disease, diarrhoea, electroencephalogram abnormal, pyrexia. ARAVA dosage: unknown. Patient recovered.
Arava Side Effects Report #5267155-0
Physician from JAPAN reported ARAVA problem on Mar 14, 2007. Female patient, 58 years of age, was diagnosed with rheumatoid arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: impaired healing, nail disorder. ARAVA dosage: unknown. During the same period patient was treated with BOUIOUGITO, LASIX, PREDONINE, BREDININ, PRAVASTATIN, LOXONIN, OMEPRAZON, PREDOHAN. Patient was hospitalized. Patient recovered.
Arava Side Effects Report #5269549-6
ARAVA problem was reported by a Consumer or non-health professional from GERMANY on Mar 15, 2007. Female patient, 56 years of age, weighting 202.8 lb, was diagnosed with rheumatoid arthritis, cystitis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: hepatitis acute. ARAVA dosage: unknown. During the same period patient was treated with ARCOXIA, ARTHROTEC, METHOTREXAT, CORTISONE ACETATE, ANTIBIOTICS. Patient was hospitalized. Patient recovered.
Arava Side Effects Report #5269550-2
Physician from UNITED STATES reported ARAVA problem on Mar 12, 2007. Female patient, weighting 252.4 lb, was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: alopecia, diarrhoea, dysphagia, erythema multiforme, gastrointestinal haemorrhage, haematochezia, liver function test abnormal, mouth ulceration, neutropenia. ARAVA dosage: unknown. During the same period patient was treated with METHOTREXATE, SKELAXIN, PREDNISONE, FOLIC ACID, AMBIEN. Patient was hospitalized. Patient recovered.
Arava Side Effects Report #5269551-4
ARAVA problem was reported by a Physician from FRANCE on Mar 13, 2007. Female patient, 78 years of age, weighting 121.3 lb, was diagnosed with rheumatoid arthritis, hypercholesterolaemia and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: dyspnoea, emphysema, fatigue, pulmonary fibrosis, respiratory failure. ARAVA dosage: unknown. During the same period patient was treated with CORTANCYL, PRACTAZIN, PAROXETINE, TAHOR, OROCAL, ERCEFURYL. Patient was hospitalized. Patient recovered.
Arava Side Effects Report #5270950-5
Consumer or non-health professional from AUSTRALIA reported ARAVA problem on Mar 14, 2007. Female patient, 71 years of age, was diagnosed with rheumatoid arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: squamous cell carcinoma. ARAVA dosage: unknown. Patient recovered.
Arava Side Effects Report #5272106-9
ARAVA problem was reported by a Physician from UNITED STATES on Mar 20, 2007. Female patient, weighting 212.0 lb, was diagnosed with rheumatoid arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: colitis. ARAVA dosage: 20 MG DAILY PO. During the same period patient was treated with HUMIRA. Patient was hospitalized. Patient recovered.
Arava Side Effects Report #5272920-X
Physician from UNITED KINGDOM reported ARAVA problem on Oct 24, 2006. Female patient, 65 years of age, was diagnosed with rheumatoid arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: pneumonitis, respiratory disorder. ARAVA dosage: unknown. Patient died.
Arava Side Effects Report #5272925-9
ARAVA problem was reported by a Physician from MEXICO on June 07, 2006. Female patient, weighting 5.73 lb, was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: cerebral ventricle dilatation. ARAVA dosage: unknown. During the same period patient was treated with DEFLAZACORT. Patient recovered.
Arava Side Effects Report #5273777-3
Physician from SPAIN reported ARAVA problem on Mar 13, 2007. Male patient, 25 years of age, was diagnosed with rheumatoid arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: blood creatine phosphokinase increased, chromaturia, rhabdomyolysis, transaminases increased. ARAVA dosage: unknown. During the same period patient was treated with DACORTIN, IBUPROFEN. Patient was hospitalized. Patient recovered.
Arava Side Effects Report #5273780-3
ARAVA problem was reported by a Physician from ITALY on Mar 15, 2007. Female patient, 63 years of age, was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: alopecia, diarrhoea, eye inflammation, gastric ulcer, gastritis, hirsutism, stomach discomfort, weight decreased. ARAVA dosage: unknown. During the same period patient was treated with CYCLOSPORINE. Patient recovered.
Arava Side Effects Report #5273781-5
Physician from GERMANY reported ARAVA problem on Mar 19, 2007. Female patient, 56 years of age, weighting 176.4 lb, was diagnosed with arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: asthenia, leukopenia, thrombocytopenia. ARAVA dosage: unknown. During the same period patient was treated with QUANTALAN, QUENSYL, CORTICOSTEROIDS, PREDNISON. Patient was hospitalized. Patient died on 03/02/2007.
Arava Side Effects Report #5275314-6
ARAVA problem was reported by a Consumer or non-health professional from AUSTRALIA on Mar 16, 2007. Female patient, 56 years of age, was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: cervix neoplasm. ARAVA dosage: unknown. During the same period patient was treated with MYFORTIC, THYROXIN. Patient recovered.
Arava Side Effects Report #5275317-1
Consumer or non-health professional from reported ARAVA problem on Mar 21, 2007. Female patient, 74 years of age, was diagnosed with rheumatoid arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: non-hodgkin's lymphoma. ARAVA dosage: unknown. During the same period patient was treated with METHOTREXATE, REMICADE. Patient was hospitalized. Patient recovered.
Arava Side Effects Report #5275320-1
ARAVA problem was reported by a Physician from FRANCE on Mar 21, 2007. Female patient, 47 years of age, was diagnosed with rheumatoid arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: lentigo maligna stage i. ARAVA dosage: unknown. During the same period patient was treated with CORTICOSTEROIDS, KETOPROFEN. Patient recovered.
Arava Side Effects Report #5278983-X
Physician from JAPAN reported ARAVA problem on Mar 26, 2007. Male patient, 77 years of age, weighting 136.7 lb, was diagnosed with polymyalgia rheumatica and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, blood lactate dehydrogenase increased, gamma-glutamyltransferase increased, glucose urine present, jaundice, liver disorder. ARAVA dosage: unknown. During the same period patient was treated with PREDONINE, AZULFIDINE. Patient was hospitalized. Patient recovered.
Arava Side Effects Report #5280443-7
ARAVA problem was reported by a Physician from ITALY on Mar 23, 2007. Male patient, 30 years of age, was diagnosed with rheumatoid arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation. ARAVA dosage: unknown. During the same period patient was treated with METHOTREXATE. Patient was hospitalized. Patient recovered.
Arava Side Effects Report #5280444-9
Health Professional from JAPAN reported ARAVA problem on Mar 26, 2007. Female patient, 75 years of age, weighting 110.2 lb, was diagnosed with rheumatoid arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: hypertension, sepsis, stomatitis, uterine cancer. ARAVA dosage: unknown. During the same period patient was treated with PREDONINE, NAIXAN, SELBEX, RHEUMATREX, RIMATIL, ISOTONIC CHLORIDE SOLUTION, ISOTONIC CHLORIDE SOLUTION, DECADRON. Patient died on 02/21/2005.
Arava Side Effects Report #5280453-X
ARAVA problem was reported by a Pharmacist from NETHERLANDS on Mar 23, 2007. Female patient, 65 years of age, weighting 136.7 lb, was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, hepatic function abnormal. ARAVA dosage: unknown. During the same period patient was treated with OMEPRAZOLE, PREDNISOLONE, ACTONEL, CALCIUM CARBONATE W. Patient was hospitalized. Patient recovered.
Arava Side Effects Report #5280454-1
Physician from NETHERLANDS reported ARAVA problem on Mar 23, 2007. Female patient, 60 years of age, was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: hepatic failure, hepatitis toxic. ARAVA dosage: unknown. During the same period patient was treated with RIVOTRIL, SELOKEEN, INFLIXIMAB. Patient was hospitalized. Patient recovered.
Arava Side Effects Report #5281704-8
ARAVA problem was reported by a Consumer or non-health professional from GREECE on Mar 06, 2007. Female patient, 31 years of age, was diagnosed with rheumatoid arthritis and was treated with ARAVA. After drug was administered, patient experienced the following problems/side effects: abortion induced. ARAVA dosage: unknown. During the same period patient was treated with PREDNISOLONE. Patient recovered.
Showing 1-50 of 492 Next >
Drug Information: Leflunomide
URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a600032.html
(le floo' na mide)IMPORTANT WARNING:
| Pregnant women and women of childbearing age who are not using a reliable method of birth control should not take leflunomide. Pregnancy must be avoided during treatment and for 2 years after treatment with leflunomide. If your period is late or you miss a period during treatment with leflunomide, call your doctor immediately. Talk to your doctor if you plan to become pregnant after stopping treatment with leflunomide. Your doctor can prescribe a treatment that will decrease the risk of harm to the fetus. |
Why is this medication prescribed?
Leflunomide is used to treat rheumatoid arthritis. Leflunomide decreases the symptoms of rheumatoid arthritis and slows damage to joints caused by the disease.
This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
How should this medicine be used?
Leflunomide comes as a tablet to take by mouth. It is usually taken once a day. You will need to take a larger dose for the first 3 days of treatment. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take leflunomide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
What special precautions should I follow?
Before taking leflunomide,
- tell your doctor and pharmacist if you are allergic to leflunomide or any other drugs.
- tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially cholestyramine (Cholybar, Questran), colestipol (Colestid), felbamate (Felbatol), mercaptopurine (Purinethol), rifampin (Rifadin, Rimactane, Rifater), methotrexate (Rheumatrex), tolbutamide (Orinase), troglitazone (Rezulin), and vitamins.
- tell your doctor if you have or have ever had liver or kidney disease, hepatitis, severe infections, or conditions affecting the bone marrow or the immune system (including human immunodeficiency virus [HIV] and acquired immunodeficiency syndrome [AIDS]).
- tell your doctor if you are breast-feeding.
- if you are planning to father a child, you should talk to your doctor about stopping leflunomide prior to conception.
- you should not receive any vaccinations while taking leflunomide unless you have talked with your doctor.
- you should know that there is a special treatment for removing leflunomide from your body once you stop taking it. Ask your doctor or pharmacist for more information about this treatment.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
Leflunomide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- diarrhea
- hair loss
- headache
- dizziness
- upset stomach
- vomiting
- stomach pain
- loss of appetite
- weight loss
- mouth sores
- runny nose
- back pain
- dry or itchy skin
- muscle pain or weakness
- flu-like symptoms
- urinary tract infection
If you experience any of the following symptoms, call your doctor immediately:
- rash
- difficulty breathing
- chest pain
- increased heart rate
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].
What storage conditions are needed for this medicine?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
What other information should I know?
Keep all appointments with your doctor. Your doctor will order certain laboratory tests to monitor your response to leflunomide.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Brand name(s):
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