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Review Argatroban Safety Reports submitted to FDA

Total Argatroban reports: 46.
Argatroban FDA safety alerts: No.
Reported deaths: 12    Reported hospitalizations: 14.
Take Argatroban Side Effects Survey, Discuss Argatroban with others
FDA Reported Argatroban Side Effects: activated partial thromboplastin time prolonged, international normalised ratio increased, coagulation time prolonged, aspartate aminotransferase increased, platelet count decreased, blood bilirubin increased, haemorrhage intracranial, hepatic function abnormal, deep vein thrombosis, epistaxis, gastrointestinal haemorrhage.
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Argatroban Side Effects Report #5671399-3
Health Professional from JAPAN reported ARGATROBAN problem on Feb 28, 2008. Male patient, 57 years of age, was diagnosed with lateral medullary syndrome, cerebral infarction and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: brain stem infarction, coma, subarachnoid haemorrhage. ARGATROBAN dosage: 10 MG, INTRAVENOUS. During the same period patient was treated with RADICUT. Patient was hospitalized. Patient died.

Argatroban Side Effects Report #5671888-1
ARGATROBAN problem was reported by a Consumer or non-health professional from JAPAN on Feb 27, 2008. Male patient, 60 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: activated partial thromboplastin time prolonged, blood alkaline phosphatase abnormal, blood bilirubin abnormal, blood lactate dehydrogenase abnormal, gamma-glutamyltransferase abnormal, hepatic function abnormal. ARGATROBAN dosage: unknown. During the same period patient was treated with AMPHOTERICIN B, ANTIBIOTICS. Patient was hospitalized and became disabled. Patient recovered.

Argatroban Side Effects Report #5692453-6
Health Professional from JAPAN reported ARGATROBAN problem on Mar 12, 2008. Male patient, 65 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: agranulocytosis. ARGATROBAN dosage: 240 MG, INTRAVENOUS; 12 MG, INTRAVENOUS. Patient recovered.

Argatroban Side Effects Report #5692468-8
ARGATROBAN problem was reported by a Consumer or non-health professional from JAPAN on Jan 21, 2008. Female patient, 58 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: deafness, dementia, dermatitis herpetiformis, dysphagia, hemicephalalgia, muscular weakness, pupils unequal, speech disorder, stupor. ARGATROBAN dosage: 50 MG, QD, INTRAVENOUS. Patient recovered.

Argatroban Side Effects Report #5615029-5
Pharmacist from UNITED STATES reported ARGATROBAN problem on Jan 22, 2008. Female patient, 56 years of age, was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, dyspnoea, granulocytosis, hepatic enzyme increased, immunosuppression. ARGATROBAN dosage: unknown. During the same period patient was treated with LOVENOX, PREDNISONE, ATROVENT, PLAVIX, POTASSIUM, TOPAMAX, IMURAN, ACCUNEB. Patient was hospitalized. Patient recovered.

Argatroban Side Effects Report #5624466-4
ARGATROBAN problem was reported by a Physician from UNITED STATES on Jan 25, 2008. Female patient, 64 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: pulmonary embolism. ARGATROBAN dosage: unknown. During the same period patient was treated with PREDNISONE, PERCOCET, LOPRESSOR, ZOFRAN, ACETAMINOPHEN. Patient was hospitalized. Patient recovered.

Argatroban Side Effects Report #5633767-5
Health Professional from JAPAN reported ARGATROBAN problem on Feb 04, 2008. Male patient, 61 years of age, was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: anorexia, dialysis, nausea, renal failure. ARGATROBAN dosage: unknown. During the same period patient was treated with RADICUT. Patient recovered.

Argatroban Side Effects Report #5640196-7
ARGATROBAN problem was reported by a Consumer or non-health professional from JAPAN on Feb 07, 2008. Male patient, 61 years of age, was diagnosed with cerebral infarction and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: anorexia, cerebral infarction, dialysis, disease recurrence, hemiplegia, nausea, renal failure. ARGATROBAN dosage: 60 MG, QD, INTRAVENOUS, 10 MG, BID, INTRAVENOUE. During the same period patient was treated with RADICUT, WARFARIN, ASPIRIN, NORVASC. Patient recovered.

Argatroban Side Effects Report #5583720-5
Consumer or non-health professional from SWEDEN reported ARGATROBAN problem on Dec 13, 2007. Female patient, 59 years of age, weighting 154.3 lb, was diagnosed with heparin-induced thrombocytopenia and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, gamma-glutamyltransferase increased. ARGATROBAN dosage: unknown. During the same period patient was treated with DALTEPARIN, TINZAPARIN. Patient recovered.

Argatroban Side Effects Report #5589302-3
ARGATROBAN problem was reported by a Consumer or non-health professional from JAPAN on Dec 26, 2007. Male patient, 78 years of age, was diagnosed with cerebral artery embolism and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: carotid artery occlusion, haemorrhagic cerebral infarction, international normalised ratio decreased, pupils unequal, renal failure acute, white blood cell count increased. ARGATROBAN dosage: 60 ML, QD, INTRAVENOUS. During the same period patient was treated with RADICUT, ACTIVASE, DEXTRAN, CHLORIDE. Patient was hospitalized. Patient recovered.

Argatroban Side Effects Report #5535093-1
Health Professional from JAPAN reported ARGATROBAN problem on Nov 15, 2007. Male patient, 70 years of age, was diagnosed with cerebral thrombosis and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: rhabdomyolysis. ARGATROBAN dosage: 20-60 MG, QD, INTRAVENOUS. During the same period patient was treated with RADICUT, SULBACILLIN. Patient was hospitalized. Patient recovered.

Argatroban Side Effects Report #5550866-7
ARGATROBAN problem was reported by a Health Professional from JAPAN on Nov 22, 2007. Male patient, 84 years of age, was diagnosed with thrombotic cerebral infarction and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: haemorrhagic cerebral infarction. ARGATROBAN dosage: 60 MG, INTRAVENOUS. During the same period patient was treated with RADICUT, NICHOLIN, GLYCEOL. Patient recovered.

Argatroban Side Effects Report #5550870-9
Health Professional from JAPAN reported ARGATROBAN problem on Nov 22, 2007. Male patient, 70 years of age, was diagnosed with cerebral thrombosis and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: pneumonia, pyrexia, renal failure acute, rhabdomyolysis. ARGATROBAN dosage: 20-60 MG, QD, INTRAVENOUS. During the same period patient was treated with RADICUT. Patient was hospitalized. Patient recovered.

Argatroban Side Effects Report #5573072-9
ARGATROBAN problem was reported by a Health Professional from JAPAN on Nov 27, 2007. Male patient, 84 years of age, was diagnosed with thrombotic stroke and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: haemorrhagic cerebral infarction. ARGATROBAN dosage: 60 MG, INTRAVENOUS, 30 MG. During the same period patient was treated with RADICUT, SOLCOSERYL, GLYCENON, SOLULACT, PHYSIO, MECLOFENOXATE HYDROCHLORIDE. Patient recovered.

Argatroban Side Effects Report #5574142-1
Health Professional from UNITED STATES reported ARGATROBAN problem on Dec 11, 2007. Female patient, 49 years of age, was diagnosed with thrombosis prophylaxis and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: activated partial thromboplastin time prolonged, coagulation time prolonged, haemoglobin decreased, hypotension, international normalised ratio increased, thrombocytopenia, thrombosis in device. ARGATROBAN dosage: 40 MG, INTRAVENOUS; 10 MG, INTRAVENOUS; 22 MG, INTRAVENOUS. During the same period patient was treated with INSULIN, CALCIUM CHLORIDE, MAGNESIUM SULPHATE, NEO SYNEPHRINE. Patient recovered.

Argatroban Side Effects Report #5510685-4
ARGATROBAN problem was reported by a Physician from UNITED STATES on Oct 24, 2007. Female patient, 54 years of age, weighting 171.1 lb, was diagnosed with heparin-induced thrombocytopenia, fungal infection and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: activated partial thromboplastin time prolonged, alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, prothrombin time prolonged. ARGATROBAN dosage: unknown. During the same period patient was treated with ITRACONAZOLE, AMPHOTERICIN B, OMEPRAZOLE, ALBUTEROL, DOCUSATE, SENNA, INSULIN, CALCIUM CARBONATE. Patient was hospitalized. Patient recovered.

Argatroban Side Effects Report #5518885-4
Health Professional from UNITED STATES reported ARGATROBAN problem on Oct 29, 2007. Female patient, 49 years of age, was diagnosed with thrombosis prophylaxis and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: procedural complication, thrombosis in device. ARGATROBAN dosage: unknown. Patient recovered.

Argatroban Side Effects Report #5522071-1
ARGATROBAN problem was reported by a Health Professional from JAPAN on Nov 01, 2007. Male patient, 70 years of age, was diagnosed with cerebral infarction, pneumonia and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, haematocrit decreased, haemoglobin decreased, haemorrhagic cerebral infarction, hepatic function abnormal. ARGATROBAN dosage: 60 MG, QD, INTRAVENOUS; 20 MG, QD, INTRAVENOUS. During the same period patient was treated with FLUMARIN, CLINDAMYCIN, ZANTAC, RADICUT, GRTPA, ASPIRIN, GAMOFA. Patient recovered.

Argatroban Side Effects Report #5522079-6
Consumer or non-health professional from JAPAN reported ARGATROBAN problem on Oct 30, 2007. Female patient, 44 years of age, was diagnosed with antithrombin iii decreased, thrombosis in device and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: cerebral haemorrhage, renal failure acute, upper gastrointestinal haemorrhage. ARGATROBAN dosage: 240 MG, QD, INTRAVENOUS. Patient died on 07/01/2007.

Argatroban Side Effects Report #5527387-0
ARGATROBAN problem was reported by a Pharmacist from UNITED STATES on Nov 07, 2007. Female patient was treated with ARGATROBAN. ARGATROBAN dosage: unknown. Patient died.

Argatroban Side Effects Report #5527388-2
Pharmacist from UNITED STATES reported ARGATROBAN problem on Nov 07, 2007. Female patient was treated with ARGATROBAN. ARGATROBAN dosage: unknown. Patient died.

Argatroban Side Effects Report #5527710-7
ARGATROBAN problem was reported by a Health Professional from JAPAN on Nov 06, 2007. Male patient, 57 years of age, was diagnosed with lateral medullary syndrome and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: coma, subarachnoid haemorrhage. ARGATROBAN dosage: unknown. Patient died.

Argatroban Side Effects Report #5534045-5
Pharmacist from UNITED STATES reported ARGATROBAN problem on Nov 29, 2007. Male patient, 90 years of age, weighting 160.0 lb, was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: ear haemorrhage, mouth haemorrhage. ARGATROBAN dosage: unknown. Patient recovered.

Argatroban Side Effects Report #5500329-X
ARGATROBAN problem was reported by a Consumer or non-health professional from JAPAN on Oct 12, 2007. Male patient, 76 years of age, was diagnosed with cerebral thrombosis and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: blood pressure increased, haemorrhagic cerebral infarction, heart rate decreased, platelet count decreased, subarachnoid haemorrhage. ARGATROBAN dosage: 60 MG, QD, INTRAVENOUS. During the same period patient was treated with GRTPA, HEPARIN, ASPIRIN, FANALDINE. Patient recovered.

Argatroban Side Effects Report #5448298-5
Health Professional from JAPAN reported ARGATROBAN problem on Aug 24, 2007. Male patient, 78 years of age, was diagnosed with heparin-induced thrombocytopenia, pulmonary embolism, disease recurrence and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: aggression, agitation, confusional state. ARGATROBAN dosage: 384 MG, INTRAVENOUS. During the same period patient was treated with UNACID, AMITRIPTYLINE HYDROCHLORIDE, ATORVASTATIN CALCIUM, METOPROLOL SUCCINATE, NOVALGIN, LAXOBERAL, DILTIAZEM. Patient recovered.

Argatroban Side Effects Report #5448520-5
ARGATROBAN problem was reported by a Physician from UNITED STATES on Aug 21, 2007. Female patient, weighting 5.95 lb, was diagnosed with heparin-induced thrombocytopenia and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: aortic valve incompetence, echocardiogram abnormal, ejection fraction decreased, heparin-induced thrombocytopenia, mitral valve incompetence, pulmonary hypertension, thrombosis, tricuspid valve incompetence. ARGATROBAN dosage: 1 MG/KG/MIN, INTRAVENOUS. During the same period patient was treated with HEPARIN. Patient was hospitalized. Patient died.

Argatroban Side Effects Report #5448597-7
Physician from UNITED STATES reported ARGATROBAN problem on Aug 21, 2007. Female patient, weighting 10.36 lb, was diagnosed with heparin-induced thrombocytopenia and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: aortic thrombosis, embolism, extremity necrosis, hypotension, labile blood pressure, lactic acidosis, vena cava thrombosis. ARGATROBAN dosage: unknown. During the same period patient was treated with HEPARIN, RED BLOOD CELLS, PLASMA, CRYOPRECIPITATE INFUSIONS. Patient died.

Argatroban Side Effects Report #5450659-5
ARGATROBAN problem was reported by a Health Professional from UNITED STATES on Aug 24, 2007. Female patient was diagnosed with heparin-induced thrombocytopenia and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: renal impairment. ARGATROBAN dosage: unknown. During the same period patient was treated with LEPIRUDIN. Patient died.

Argatroban Side Effects Report #5472251-9
Physician from UNITED STATES reported ARGATROBAN problem on Sept 10, 2007. Male patient, 59 years of age, weighting 142.0 lb, was diagnosed with heparin-induced thrombocytopenia and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: activated partial thromboplastin time shortened, platelet count abnormal. ARGATROBAN dosage: unknown. During the same period patient was treated with NORVASC, LASIX, PREDNISONE, DEXAMETHASONE, PROTONIX, SENNA, COLACE, INSULIN. Patient was hospitalized. Patient recovered.

Argatroban Side Effects Report #5473045-0
ARGATROBAN problem was reported by a Consumer or non-health professional from JAPAN on Sept 14, 2007. Male patient, 70 years of age, was diagnosed with cerebral infarction, pneumonia and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, haematocrit decreased, haemorrhagic cerebral infarction, hepatic function abnormal. ARGATROBAN dosage: 60 MG, QD, INTRAVENOUS; 20 MG, QD, INTRAVENOUS. During the same period patient was treated with FLUMARIN, ZANTAC, RADICURT, GRTPA, ASPIRIN, GAMOFA, WARFARIN. Patient recovered.

Argatroban Side Effects Report #5420058-0
Health Professional from JAPAN reported ARGATROBAN problem on Aug 03, 2007. Male patient, 72 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: conjunctival haemorrhage, convulsion, haemoptysis, haemorrhage intracranial, petechiae. ARGATROBAN dosage: unknown. During the same period patient was treated with LOPRESSOR, MEXILETINE HYDROCHLORIDE, LIDOCAINE, POLARAMINE. Patient recovered.

Argatroban Side Effects Report #5421168-4
ARGATROBAN problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 09, 2007. Female patient, 32 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: activated partial thromboplastin time prolonged, international normalised ratio increased. ARGATROBAN dosage: unknown. During the same period patient was treated with WARFARIN. Patient was hospitalized. Patient recovered.

Argatroban Side Effects Report #5422308-3
Health Professional from JAPAN reported ARGATROBAN problem on Aug 02, 2007. Male patient, 71 years of age, was diagnosed with cerebral thrombosis and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: blood fibrinogen increased, deep vein thrombosis, hepatic function abnormal, liver disorder, pneumonia aspiration, restlessness. ARGATROBAN dosage: 60 MG, BID, INTRAVENOUS. During the same period patient was treated with RADICUT, GRTPA, ISOSORBIDE DINITRATE, LOW MOLECULAR DEXTRAN, FAMOTIDINE, ASPIRINA BAYER, LANSOPRAZOLE. Patient recovered.

Argatroban Side Effects Report #5427464-9
ARGATROBAN problem was reported by a Pharmacist from UNITED STATES on Aug 24, 2007. Female patient, 73 years of age, weighting 257.9 lb, was diagnosed with heparin-induced thrombocytopenia and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, dialysis, hepatic function abnormal, renal failure acute. ARGATROBAN dosage: unknown. Patient recovered.

Argatroban Side Effects Report #5430603-7
Consumer or non-health professional from JAPAN reported ARGATROBAN problem on Aug 10, 2007. Female patient, 75 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: anaemia, cardiac failure, epistaxis, operative haemorrhage. ARGATROBAN dosage: unknown. Patient recovered.

Argatroban Side Effects Report #5430606-2
ARGATROBAN problem was reported by a Consumer or non-health professional from JAPAN on Aug 10, 2007. Male patient, 73 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: liver disorder. ARGATROBAN dosage: unknown. During the same period patient was treated with VASOLAN, RYTHMODAN, CIBENOL, XYLOCAINE, PRIMAXIN, SULPERAZON. Patient recovered.

Argatroban Side Effects Report #5391625-8
Consumer or non-health professional from JAPAN reported ARGATROBAN problem on June 15, 2007. Female patient, weighting 1.98 lb, was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: premature baby, small for dates baby. ARGATROBAN dosage: unknown. Patient recovered.

Argatroban Side Effects Report #5392843-5
ARGATROBAN problem was reported by a Health Professional from GERMANY on July 02, 2007. Male patient, 53 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: activated partial thromboplastin time prolonged, activated partial thromboplastin time shortened, aspartate aminotransferase increased, blood bilirubin increased, coagulation time prolonged, haemorrhage, septic shock. ARGATROBAN dosage: unknown. During the same period patient was treated with HEPARIN, ACYCLOVIR, CAPTOPRIL, VIAGRA, DIFLUCAN, ERYTHROMYCIN, VANCOMYCIN, RIFAMPICIN. Patient died on 09/02/2005.

Argatroban Side Effects Report #5400030-7
Consumer or non-health professional from JAPAN reported ARGATROBAN problem on July 10, 2007. Female patient, 44 years of age, was diagnosed with antithrombin iii decreased, thrombosis in device and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: cerebral haemorrhage, haemorrhagic diathesis, upper gastrointestinal haemorrhage. ARGATROBAN dosage: 240 MG, QD, INTRAVENOUS. Patient died on 07/01/2007.

Argatroban Side Effects Report #5400031-9
ARGATROBAN problem was reported by a Consumer or non-health professional from JAPAN on June 27, 2007. Male patient, 75 years of age, was diagnosed with cerebral thrombosis and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: blood pressure diastolic increased, haemorrhagic cerebral infarction, heart rate decreased, platelet count decreased, subarachnoid haemorrhage. ARGATROBAN dosage: 60 MG, QD, INTRAVENOUS. During the same period patient was treated with GRTPA, HEPARIN, ASPIRIN, FANALDINE. Patient recovered.

Argatroban Side Effects Report #5400566-9
Health Professional from JAPAN reported ARGATROBAN problem on July 12, 2007. Male patient, 67 years of age, was diagnosed with cerebral infarction and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: granulocyte count decreased. ARGATROBAN dosage: unknown. During the same period patient was treated with RADICUT, CITICOLINE, DEXTRAN L, CHLORIDE, SOLCOSERYL. Patient was hospitalized. Patient recovered.

Argatroban Side Effects Report #5391625-8
ARGATROBAN problem was reported by a Consumer or non-health professional from JAPAN on June 15, 2007. Female patient, weighting 1.98 lb, was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: premature baby, small for dates baby. ARGATROBAN dosage: unknown. Patient recovered.

Argatroban Side Effects Report #5392843-5
Health Professional from GERMANY reported ARGATROBAN problem on July 02, 2007. Male patient, 53 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: activated partial thromboplastin time prolonged, activated partial thromboplastin time shortened, aspartate aminotransferase increased, blood bilirubin increased, coagulation time prolonged, haemorrhage, septic shock. ARGATROBAN dosage: unknown. During the same period patient was treated with HEPARIN, ACYCLOVIR, CAPTOPRIL, VIAGRA, DIFLUCAN, ERYTHROMYCIN, VANCOMYCIN, RIFAMPICIN. Patient died on 09/02/2005.

Argatroban Side Effects Report #5400030-7
ARGATROBAN problem was reported by a Consumer or non-health professional from JAPAN on July 10, 2007. Female patient, 44 years of age, was diagnosed with antithrombin iii decreased, thrombosis in device and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: cerebral haemorrhage, haemorrhagic diathesis, upper gastrointestinal haemorrhage. ARGATROBAN dosage: 240 MG, QD, INTRAVENOUS. Patient died on 07/01/2007.

Argatroban Side Effects Report #5400031-9
Consumer or non-health professional from JAPAN reported ARGATROBAN problem on June 27, 2007. Male patient, 75 years of age, was diagnosed with cerebral thrombosis and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: blood pressure diastolic increased, haemorrhagic cerebral infarction, heart rate decreased, platelet count decreased, subarachnoid haemorrhage. ARGATROBAN dosage: 60 MG, QD, INTRAVENOUS. During the same period patient was treated with GRTPA, HEPARIN, ASPIRIN, FANALDINE. Patient recovered.

Argatroban Side Effects Report #5400566-9
ARGATROBAN problem was reported by a Health Professional from JAPAN on July 12, 2007. Male patient, 67 years of age, was diagnosed with cerebral infarction and was treated with ARGATROBAN. After drug was administered, patient experienced the following problems/side effects: granulocyte count decreased. ARGATROBAN dosage: unknown. During the same period patient was treated with RADICUT, CITICOLINE, DEXTRAN L, CHLORIDE, SOLCOSERYL. Patient was hospitalized. Patient recovered.