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From simple mix-ups to fatal overdoses, medication mistakes happen, on average, once a day to every hospital patient, a new report says. Nationwide, at least 1.5 million people annually are harmed from drug errors, more than half of them in nursing homes.
Many Unfavorable Drug Studies Aren’t Published. Nearly a third of antidepressant drug studies are never published in the medical literature, and nearly all of those happen to show that the drug being tests failed to work.
Only Drugs That are Safe Should be put on the Market. Drug developers are just beginning to come to grips with recent FDA oversight reforms and how they will affect drug safety. But, it appears that industry and consumer advocates are not together on how well the overhaul will be able to prevent future drug safety scandals.

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Review Benazepril Safety Reports submitted to FDA

Total Benazepril reports: 25.
Benazepril FDA safety alerts: No.
   Reported hospitalizations: 15.
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FDA Reported Benazepril Side Effects: dyspnoea, dizziness, blood pressure increased, collapse of lung, alveolitis allergic, hypertension, angioneurotic oedema, cardiac failure congestive, diarrhoea, angioedema, hyperkalaemia.
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Benazepril Side Effects Report #5211574-5
Physician from UNITED STATES reported BENAZEPRIL problem on Jan 16, 2007. Female patient was diagnosed with hypertension and was treated with BENAZEPRIL. After drug was administered, patient experienced the following problems/side effects: dizziness, fatigue, nausea, paraesthesia. BENAZEPRIL dosage: 20 MG 1 PER DAY MOUTH [2 MS ON + OCTOBER 06OFF]. During the same period patient was treated with LOVASTATIN. Patient recovered.

Benazepril Side Effects Report #5212941-6
BENAZEPRIL problem was reported by a Pharmacist from UNITED STATES on Jan 17, 2007. Male patient, 77 years of age, weighting 165.0 lb, was diagnosed with hypertension and was treated with BENAZEPRIL. After drug was administered, patient experienced the following problems/side effects: dyspnoea, headache, productive cough, sputum discoloured, throat irritation. BENAZEPRIL dosage: 20 MG DAILY PO. During the same period patient was treated with ATENOLOL, CLOPIRDOGREL, HYDROCHLOROTHIAZIDE, LORATADINE, MOMETASONE FUROATE, ROSUVASTATIN. Patient was hospitalized. Patient recovered.

Benazepril Side Effects Report #5225741-8
Consumer or non-health professional from UNITED STATES reported BENAZEPRIL problem on Jan 31, 2007. Female patient, weighting 138.0 lb, was diagnosed with hypertension and was treated with BENAZEPRIL. After drug was administered, patient experienced the following problems/side effects: blood pressure increased, dizziness, impaired work ability. BENAZEPRIL dosage: 10 MG 1 QD. Patient recovered.

Benazepril Side Effects Report #5241063-3
BENAZEPRIL problem was reported by a Pharmacist from UNITED STATES on Feb 14, 2007. Male patient, 56 years of age, weighting 262.8 lb, was diagnosed with hypertension and was treated with BENAZEPRIL. After drug was administered, patient experienced the following problems/side effects: renal failure acute. BENAZEPRIL dosage: unknown. During the same period patient was treated with IBUPROFEN, ALPRAZOLAM, ASPIRIN, ATENOLOL, BACLOFEN, CALCIUM, FLUVASTATIN, GEMFIBROZIL. Patient was hospitalized. Patient recovered.

Benazepril Side Effects Report #5252603-2
Pharmacist from UNITED STATES reported BENAZEPRIL problem on Feb 27, 2007. Male patient, 39 years of age, weighting 248.0 lb, was diagnosed with aortic dissection and was treated with BENAZEPRIL. After drug was administered, patient experienced the following problems/side effects: aortic dissection, blood pressure decreased, blood pressure systolic increased, cardio-respiratory arrest, loss of consciousness, pulse absent. BENAZEPRIL dosage: unknown. During the same period patient was treated with FELODIPINE, LABETALOL. Patient recovered.

Benazepril Side Effects Report #5268275-7
BENAZEPRIL problem was reported by a Pharmacist from UNITED STATES on Mar 14, 2007. Female patient, 88 years of age, was diagnosed with cardiac failure congestive and was treated with BENAZEPRIL. After drug was administered, patient experienced the following problems/side effects: bradycardia, hyperkalaemia, renal failure acute. BENAZEPRIL dosage: 5 MG DAILY PO. During the same period patient was treated with SPIRONOLACTONE, FUROSEMIDE, KCL SUPPLEMENT. Patient was hospitalized. Patient recovered.

Benazepril Side Effects Report #5270752-X
Consumer or non-health professional from UNITED STATES reported BENAZEPRIL problem on Mar 19, 2007. Male patient, 71 years of age, weighting 175.0 lb, was diagnosed with hypertension and was treated with BENAZEPRIL. After drug was administered, patient experienced the following problems/side effects: blood pressure increased. BENAZEPRIL dosage: unknown. Patient recovered.

Benazepril Side Effects Report #5277129-1
BENAZEPRIL problem was reported by a Pharmacist from UNITED STATES on Mar 22, 2007. Female patient, 69 years of age, weighting 138.9 lb, was diagnosed with hypertension and was treated with BENAZEPRIL. After drug was administered, patient experienced the following problems/side effects: angioedema. BENAZEPRIL dosage: 20 MG DAILY PO. Patient was hospitalized. Patient recovered.

Benazepril Side Effects Report #5302017-1
Pharmacist from UNITED STATES reported BENAZEPRIL problem on Apr 16, 2007. Female patient, 44 years of age, was treated with BENAZEPRIL. After drug was administered, patient experienced the following problems/side effects: angioedema. BENAZEPRIL dosage: 40 MG PO. During the same period patient was treated with LOSARTAN POTASSIUM. Patient was hospitalized. Patient recovered.

Benazepril Side Effects Report #5306787-8
BENAZEPRIL problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 23, 2007. Female patient, 52 years of age, weighting 170.0 lb, was diagnosed with hypertrophic cardiomyopathy and was treated with BENAZEPRIL. After drug was administered, patient experienced the following problems/side effects: abdominal distension, abdominal rigidity, chest discomfort, cold sweat, diarrhoea, dyspnoea, erythema, flatulence, hyperhidrosis. BENAZEPRIL dosage: unknown. Patient was hospitalized. Patient recovered.

Benazepril Side Effects Report #5332329-7
Health Professional from UNITED STATES reported BENAZEPRIL problem on May 21, 2007. Female patient, 62 years of age, weighting 140.0 lb, was diagnosed with hypertension and was treated with BENAZEPRIL. After drug was administered, patient experienced the following problems/side effects: feeling abnormal, nausea. BENAZEPRIL dosage: unknown. Patient recovered.

Benazepril Side Effects Report #5341823-4
BENAZEPRIL problem was reported by a Consumer or non-health professional from UNITED STATES on May 29, 2007. Male patient, 29 years of age, weighting 250.0 lb, was diagnosed with blood pressure and was treated with BENAZEPRIL. After drug was administered, patient experienced the following problems/side effects: arthritis. BENAZEPRIL dosage: 20 MG 1 TIME PER DAY CUTANEOUS. Patient was hospitalized. Patient recovered.

Benazepril Side Effects Report #5065912-7
Pharmacist from UNITED STATES reported BENAZEPRIL problem on July 28, 2006. Male patient, 37 years of age, weighting 235.0 lb, was diagnosed with hypertension and was treated with BENAZEPRIL. After drug was administered, patient experienced the following problems/side effects: gastrointestinal haemorrhage, intubation complication, laryngospasm, laryngotracheal oedema, post procedural complication. BENAZEPRIL dosage: 20 MG DAILY PO. Patient was hospitalized. Patient recovered.

Benazepril Side Effects Report #5130547-4
BENAZEPRIL problem was reported by a Consumer or non-health professional from UNITED STATES on Oct 05, 2006. Male patient, 42 years of age, was treated with BENAZEPRIL. After drug was administered, patient experienced the following problems/side effects: cardiac failure congestive, pericardial effusion. BENAZEPRIL dosage: unknown. During the same period patient was treated with FUROSEMIDE. Patient was hospitalized. Patient recovered.

Benazepril Side Effects Report #5141655-6
Pharmacist from UNITED STATES reported BENAZEPRIL problem on Oct 30, 2006. Male patient, 67 years of age, weighting 227.1 lb, was diagnosed with cardiac failure congestive, hypertension and was treated with BENAZEPRIL. After drug was administered, patient experienced the following problems/side effects: cardiac failure congestive, chest pain, dysphagia, swelling, throat tightness. BENAZEPRIL dosage: 5 MG QDAY PO. During the same period patient was treated with BENAZEPRIL HYDROCHLORIDE. Patient recovered.

Benazepril Side Effects Report #5143195-7
BENAZEPRIL problem was reported by a Health Professional from UNITED STATES on Oct 31, 2006. Male patient, 51 years of age, was diagnosed with hypertension and was treated with BENAZEPRIL. After drug was administered, patient experienced the following problems/side effects: angioneurotic oedema, hypertension, oedema mouth, swollen tongue. BENAZEPRIL dosage: unknown. During the same period patient was treated with VYTORIN, VALSARTAN, CARVEDILOL. Patient recovered.

Benazepril Side Effects Report #5164281-1
Pharmacist from UNITED STATES reported BENAZEPRIL problem on Nov 28, 2006. Male patient, 64 years of age, was treated with BENAZEPRIL. After drug was administered, patient experienced the following problems/side effects: angioneurotic oedema. BENAZEPRIL dosage: 20 MG DAILY PO. Patient was hospitalized. Patient recovered.

Benazepril Side Effects Report #5178918-4
BENAZEPRIL problem was reported by a Health Professional from UNITED STATES on Dec 13, 2006. Female patient, 70 years of age, was diagnosed with hypertension and was treated with BENAZEPRIL. After drug was administered, patient experienced the following problems/side effects: blood pressure increased. BENAZEPRIL dosage: 5 MG 2/DAY PO. Patient recovered.

Benazepril Side Effects Report #5397539-1
Pharmacist from UNITED STATES reported BENAZEPRIL problem on July 24, 2007. Male patient, 50 years of age, was diagnosed with hypertension and was treated with BENAZEPRIL. After drug was administered, patient experienced the following problems/side effects: lip swelling, paraesthesia, speech disorder. BENAZEPRIL dosage: unknown. Patient was hospitalized. Patient recovered.

Benazepril Side Effects Report #5398341-7
BENAZEPRIL problem was reported by a Consumer or non-health professional from UNITED STATES on July 09, 2007. Female patient, 57 years of age, was diagnosed with hypertension and was treated with BENAZEPRIL. After drug was administered, patient experienced the following problems/side effects: alveolitis allergic, collapse of lung, dyspnoea, lung infiltration. BENAZEPRIL dosage: 20 MG;DAILY;ORAL. Patient was hospitalized. Patient recovered.

Benazepril Side Effects Report #5420859-9
Consumer or non-health professional from UNITED STATES reported BENAZEPRIL problem on Aug 03, 2007. Female patient, 57 years of age, weighting 229.0 lb, was diagnosed with hypertension and was treated with BENAZEPRIL. After drug was administered, patient experienced the following problems/side effects: alveolitis allergic, collapse of lung, dyspnoea, eosinophilic pneumonia, hypoxia. BENAZEPRIL dosage: 20 MG; TWICE A DAY; ORAL. During the same period patient was treated with NOVOLIN, PROTONIX, TOPROL, DIOVAN, THYROID. Patient was hospitalized and became disabled. Patient recovered.

Benazepril Side Effects Report #5424684-4
BENAZEPRIL problem was reported by a Health Professional from UNITED STATES on Aug 22, 2007. Female patient, 75 years of age, weighting 116.0 lb, was diagnosed with hypertension and was treated with BENAZEPRIL. After drug was administered, patient experienced the following problems/side effects: depressed mood, diarrhoea, dizziness, hot flush, pruritus, rash. BENAZEPRIL dosage: 10-20MG QD PO CAPSULE. Patient recovered.

Benazepril Side Effects Report #5424709-6
Consumer or non-health professional from UNITED STATES reported BENAZEPRIL problem on Aug 22, 2007. Female patient, 97 years of age, weighting 192.0 lb, was treated with BENAZEPRIL. After drug was administered, patient experienced the following problems/side effects: activities of daily living impaired, cerebrovascular accident. BENAZEPRIL dosage: 20 MG. During the same period patient was treated with NITROGLYCERIN. Patient was hospitalized. Patient recovered.

Benazepril Side Effects Report #5424716-3
BENAZEPRIL problem was reported by a Pharmacist from UNITED STATES on Aug 22, 2007. Male patient, 72 years of age, was diagnosed with hypertension and was treated with BENAZEPRIL. After drug was administered, patient experienced the following problems/side effects: hyperkalaemia. BENAZEPRIL dosage: 10MG EVERY DAY PO. Patient was hospitalized. Patient recovered.

Benazepril Side Effects Report #5460088-6
Consumer or non-health professional from UNITED STATES reported BENAZEPRIL problem on June 14, 2006. Female patient, 58 years of age, weighting 280.0 lb, was diagnosed with hypertension and was treated with BENAZEPRIL. After drug was administered, patient experienced the following problems/side effects: dizziness, hypertension, vision blurred. BENAZEPRIL dosage: 20 MG, QD, ORAL. During the same period patient was treated with ATENOLOL, HYDROCHLOROTHIAZIDE, SINGULAIR, ZOLOFT. Patient recovered.


Drug Information: Benazepril

URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a692011.html

(ben ay' ze pril)

IMPORTANT WARNING:

Do not take benazepril if you are pregnant. If you become pregnant while taking benazepril, call your doctor immediately. Benazepril may harm the fetus.

Why is this medication prescribed?

Benazepril is used alone or in combination with other medications to treat high blood pressure. Benazepril is in a class of medications called angiotensin-converting enzyme (ACE) inhibitors. It works by decreasing certain chemicals that tighten the blood vessels, so blood flows more smoothly.

How should this medicine be used?

Benazepril comes as a tablet to take by mouth. It is usually taken once or twice a day with or without food. To help you remember to take benazepril, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take benazepril exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor will probably start you on a low dose of benazepril and gradually increase your dose.

Benazepril controls high blood pressure but does not cure it. Continue to take benazepril even if you feel well. Do not stop taking benazepril without talking to your doctor.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking benazepril,

  • tell your doctor and pharmacist if you are allergic to benazepril, captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), trandolapril (Mavik), or any other medications.
  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: diuretics ('water pills'), lithium (Eskalith, Lithobid), and potassium supplements. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have recently had severe diarrhea or vomiting and if you have or have ever had heart failure, kidney disease, lupus, scleroderma, or diabetes.
  • tell your doctor if you plan to become pregnant or are breast-feeding.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking benazepril.
  • you should know that diarrhea, vomiting, not drinking enough fluids, and sweating a lot can cause a drop in blood pressure, which may cause lightheadedness and fainting.

What special dietary instructions should I follow?

Talk to your doctor before using salt substitutes containing potassium. If your doctor prescribes a low-salt or low-sodium diet, follow these directions carefully.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Benazepril may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • cough
  • headache
  • dizziness
  • drowsiness

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:

  • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
  • hoarseness
  • difficulty breathing or swallowing
  • lightheadedness
  • fainting
  • rash
  • yellowing of the skin or eyes
  • fever, sore throat, chills, and other signs of infection

Benazepril may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include:

  • dizziness
  • fainting

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your blood pressure should be checked regularly to determine your response to benazepril. Your doctor may order certain lab tests to check your body's response to benazepril.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand name(s):

  • Lotensin®

Brand name(s) of combination products:

  • Lotensin® HCT containing Benazepril Hydrochloride and Hydrochlorothiazide
  • Lotrel® containing Benazepril Hydrochloride and Amlodipine Besylate

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dizziness, fatigue, nausea, paraesthesia dyspnoea, headache, productive cough, sputum discoloured, throat irritation, was diagnosed with hypertension and was diagnosed with hypertension and was diagnosed with hypertension and