BUPHENYL Side Effects

6933097-5 | Ataxia, Brain Oedema, Dialysis, Disorientation, Hyperammonaemia, Life Support, Product Quality Issue, Vomiting
on Aug 02, 2010 Female patient from UNITED STATES , child 6 years of age, weighting 33.00 lb, was diagnosed with amino acid metabolism disorder and was treated with Buphenyl (View Usage). Patient experienced the following unwanted or unexpected effects: ataxia (What is ataxia?), brain oedema, dialysis (What is dialysis?), disorientation, hyperammonaemia, life support, product quality issue, vomiting. Buphenyl dosage: 7 G; Qd; Po. During the same period patient was treated with CYCLINEX (View Cyclinex Review and Cyclinex Label ), L ARGININE (View L-arginine Review and L-arginine Label ), PRO PHREE (View Pro-phree Review and Pro-phree Label ). Patient was hospitalized.

6925101-5 | Convulsion, Joint Dislocation
Patient was taking Buphenyl (View Usage). Patient had the following side effects: convulsion, joint dislocation on Jul 27, 2010 from UNITED STATES Additional patient health information: Male patient , 23 years of age, was diagnosed with amino acid metabolism disorder and. Buphenyl dosage: 9.9 G; Bid; Po. Patient was hospitalized.

6499776-1 | Dehydration, Eating Disorder, Gastroenteritis Viral, Irritability, Somnolence
Adverse event was reported on Dec 01, 2009 by a Male patient taking Buphenyl (View Usage) (Dosage: 1500 Mg Q 8 Hrs, Gastrostomy Tube) was diagnosed with amino acid metabolism disorder and. Location: UNITED STATES , weighting 19.00 lb, After Buphenyl was administered, patient had the following side effects: dehydration, eating disorder (What is eating disorder?), gastroenteritis viral, irritability, somnolence. During the same period patient was treated with VIAGRA (View Viagra Review and Viagra Label ). Patient was hospitalized.

6480459-9 | Dehydration, Eating Disorder, Irritability, Nausea, Retching, Somnolence, Viral Infection
on Nov 18, 2009 Male patient from UNITED STATES , weighting 19.00 lb, was diagnosed with amino acid metabolism disorder and was treated with Buphenyl (View Usage). Patient experienced the following unwanted or unexpected effects: dehydration, eating disorder (What is eating disorder?), irritability, nausea (What is nausea?), retching, somnolence, viral infection (What is viral infection?). Buphenyl dosage: 1500 Mg Q 8 Hrs, Gastrostomy Tube. Patient was hospitalized.


6207344-1 | Acute Respiratory Failure, Anaemia, Autonomic Nervous System Imbalance, Brain Herniation, Cardio-respiratory Arrest, Developmental Delay, Gastritis, Hyperammonaemia
on May 13, 2009 Male patient from UNITED STATES , 19 years of age, weighting 68.20 lb, was diagnosed with ornithine transcarbamoylase deficiency and was treated with Buphenyl (View Usage). Patient had the following side effects: acute respiratory failure, anaemia, autonomic nervous system imbalance, brain herniation, cardio-respiratory arrest, developmental delay, gastritis, hyperammonaemia. Buphenyl dosage: 3000 Mg, 5 Times Daily, Other. During the same period patient was treated with FLUCONAZOLE (200 Mg, Once Daily, Other) (View Fluconazole Review and Fluconazole Label ), ROBINUL (View Robinul Review and Robinul Label ), TYLENOL (CAPLET) (View Tylenol (caplet) Review and Tylenol (caplet) Label ), TEGRETOL (View Tegretol Review and Tegretol Label ), NEBULIZED RACEMIC EPINEPHRINE (View Nebulized Racemic Epinephrine Review and Nebulized Racemic Epinephrine Label ), HEP FLUSH KIT (View Hep Flush Kit Review and Hep Flush Kit Label ), IBUPROFEN LIQUID (View Ibuprofen Liquid Review and Ibuprofen Liquid Label ). Patient was hospitalized.

6179858-4 | Ammonia Increased, Cardio-respiratory Arrest, Incorrect Dose Administered, Lethargy
Patient was taking Buphenyl (View Usage). After Buphenyl was administered, patient had the following side effects: ammonia increased, cardio-respiratory arrest, incorrect dose administered, lethargy on Apr 17, 2009 from UNITED STATES Additional patient health information: Male patient , 19 years of age, weighting 68.20 lb, was diagnosed with amino acid metabolism disorder and. Buphenyl dosage: 3000 Mg, 5 Times Daily, Other. During the same period patient was treated with FLUCONAZOLE (200 Mg, Once Daily, Other) (View Fluconazole Review and Fluconazole Label ), ROBINUL (View Robinul Review and Robinul Label ), TYLENOL (CAPLET) (View Tylenol (caplet) Review and Tylenol (caplet) Label ), TEGRETOL (View Tegretol Review and Tegretol Label ), NEBULIZED RACEMIC EPINEPHRINE (View Nebulized Racemic Epinephrine Review and Nebulized Racemic Epinephrine Label ), HEP FLUSH KIT (View Hep Flush Kit Review and Hep Flush Kit Label ), IBUPROFEN LIQUID (View Ibuprofen Liquid Review and Ibuprofen Liquid Label ). Patient was hospitalized.

5988212-7 | Antinuclear Antibody Increased, Coordination Abnormal, Dehydration, Dysphagia, Erythromelalgia, Headache, Inflammation, Liver Function Test Abnormal, Rash
Adverse event was reported on Nov 18, 2008 by a Female patient taking Buphenyl (View Usage) (Dosage: 12 Tabs 3x/daily Orally) was diagnosed with ammonia increased and. Location: UNITED STATES , 43 years of age, weighting 234.0 lb, Patient experienced the following unwanted or unexpected effects: antinuclear antibody increased, coordination abnormal, dehydration, dysphagia, erythromelalgia, headache (What is headache?), inflammation, liver function test abnormal, rash (What is rash?). During the same period patient was treated with RITALIN (View Ritalin Review and Ritalin Label ), ADDERALL 10 (View Adderall 10 Review and Adderall 10 Label ), PROVIGIL (View Provigil Review and Provigil Label ), ZYRTEC (View Zyrtec Review and Zyrtec Label ), CODEINE SUL TAB (View Codeine Sul Tab Review and Codeine Sul Tab Label ), FLEXERIL (View Flexeril Review and Flexeril Label ), DOXYCYCLINE (View Doxycycline Review and Doxycycline Label ), ACYCLOVIR (View Acyclovir Review and Acyclovir Label ). Patient was hospitalized.

5978644-5 | Antinuclear Antibody Increased, Dysphagia, Erythromelalgia, Headache, Oedema Peripheral, Treatment Noncompliance, Weight Increased
on Nov 18, 2008 Female patient from UNITED STATES , 43 years of age, weighting 234.0 lb, was diagnosed with ammonia increased and was treated with Buphenyl (View Usage). Patient had the following side effects: antinuclear antibody increased, dysphagia, erythromelalgia, headache (What is headache?), oedema peripheral, treatment noncompliance, weight increased. Buphenyl dosage: 12 Tabs 3x/daily Orally. During the same period patient was treated with RITALIN (View Ritalin Review and Ritalin Label ), ADDERALL 10 (View Adderall 10 Review and Adderall 10 Label ), PROVIGIL (View Provigil Review and Provigil Label ), ZYRTEC (View Zyrtec Review and Zyrtec Label ), CODEINE SUL TAB (View Codeine Sul Tab Review and Codeine Sul Tab Label ), FLEXERIL (View Flexeril Review and Flexeril Label ), DOXCYCLINE (View Doxcycline Review and Doxcycline Label ), ACYCLOVIR (View Acyclovir Review and Acyclovir Label ).

5274515-0 | Abnormal Behaviour, Ammonia Increased, Anuria, Blood Sodium Increased, Brain Damage, Coagulopathy, Haemodialysis, Hepatic Failure
on Mar 03, 2007 Male patient from UNITED STATES , weighting 6.61 lb, was diagnosed with hyperammonaemia and was treated with Buphenyl (View Usage). After Buphenyl was administered, patient had the following side effects: abnormal behaviour, ammonia increased, anuria, blood sodium increased, brain damage, coagulopathy, haemodialysis, hepatic failure. Buphenyl dosage: See Image. During the same period patient was treated with AMMONUL (SODIUM PHENYLACETATE/SODIUM BENZOATE) (View Ammonul (sodium Phenylacetate/sodium Benzoate) Review and Ammonul (sodium Phenylacetate/sodium Benzoate) Label ), CITRULLINE (View Citrulline Review and Citrulline Label ), PHENOBARBITAL TAB (View Phenobarbital Tab Review and Phenobarbital Tab Label ).

5251806-0 | Blood Test Abnormal, Haemodialysis, Hepatic Failure, Infantile Spitting Up, Overdose, Unresponsive To Stimuli
Patient was taking Buphenyl (View Usage). Patient experienced the following unwanted or unexpected effects: blood test abnormal, haemodialysis, hepatic failure, infantile spitting up, overdose, unresponsive to stimuli on Feb 08, 2007 from UNITED STATES Additional patient health information: Male patient , weighting 6.61 lb, was diagnosed with amino acid metabolism disorder and. Buphenyl dosage: 450 Mg/kg Q6h Via Ngt. During the same period patient was treated with AMMONUL (SODIUM PHENYLACETATE/SODIUM BENZOATE) (View Ammonul (sodium Phenylacetate/sodium Benzoate) Review and Ammonul (sodium Phenylacetate/sodium Benzoate) Label ), CITRULLINE (View Citrulline Review and Citrulline Label ), PHENOBARBITAL TAB (View Phenobarbital Tab Review and Phenobarbital Tab Label ).

5013448-1 | Cardiac Arrest, Hyperammonaemia, Hypokalaemia, Procedural Complication, Ventricular Tachycardia
Adverse event was reported on Feb 24, 2005 by a Female patient taking Buphenyl (View Usage) (Dosage: 6 G Dailypo) was diagnosed with ornithine transcarbamoylase deficiency and. Location: UNITED STATES , child 9 years of age, Patient had the following side effects: cardiac arrest (What is cardiac arrest?), hyperammonaemia, hypokalaemia, procedural complication, ventricular tachycardia. During the same period patient was treated with ORAL CITRULLINE (View Oral Citrulline Review and Oral Citrulline Label ), GLUCOSE (View Glucose Review and Glucose Label ), INSULIN (View Insulin Review and Insulin Label ), INTRALIPIDS (View Intralipids Review and Intralipids Label ), AMMONUL (View Ammonul Review and Ammonul Label ).

4969264-X | Cardiac Arrest, Dialysis, Hyperammonaemia, Hypokalaemia, Ventricular Tachycardia
on Feb 24, 2005 Female patient from UNITED STATES , child 9 years of age, was diagnosed with ornithine transcarbamoylase deficiency and was treated with Buphenyl (View Usage). After Buphenyl was administered, patient had the following side effects: cardiac arrest (What is cardiac arrest?), dialysis (What is dialysis?), hyperammonaemia, hypokalaemia, ventricular tachycardia. Buphenyl dosage: 6 G Daily Po. During the same period patient was treated with ORAL CITRULLINE (View Oral Citrulline Review and Oral Citrulline Label ), GLUCOSE (View Glucose Review and Glucose Label ), INSULIN (View Insulin Review and Insulin Label ), INTRALIPIDS (View Intralipids Review and Intralipids Label ), AMMONUL (View Ammonul Review and Ammonul Label ).

4641777-X | Neuropathy Peripheral
on Apr 12, 2005 Female patient from , 25 years of age, was diagnosed with blood urea abnormal and was treated with Buphenyl (View Usage). Patient experienced the following unwanted or unexpected effects: neuropathy peripheral. Buphenyl dosage: 1 Tbsp Tid Po. During the same period patient was treated with L CITRULLINE (View L- Citrulline Review and L- Citrulline Label ), CARNITOR (View Carnitor Review and Carnitor Label ), TRI0DYCLEAN (View Tri0dyclean Review and Tri0dyclean Label ), CYMBALTA (View Cymbalta Review and Cymbalta Label ), MS CONTIN (View Ms Contin Review and Ms Contin Label ), WELLBUTTN (View Wellbuttn Review and Wellbuttn Label ), XANAX (View Xanax Review and Xanax Label ), ULTRAM (View Ultram Review and Ultram Label ).