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Burinex Side Effects

Common Burinex Side Effects


The most commonly reported Burinex side effects (click to view or check a box to report):

Hypokalaemia (2)
Diabetes Mellitus Inadequate Control (1)
Constipation (1)
Blood Osmolarity Decreased (1)
Hyponatraemia (1)
Hypovolaemic Shock (1)
Weight Increased (1)
Lactic Acidosis (1)
Ileus (1)
Blood Creatinine Increased (1)
Myocardial Infarction (1)
Rash Macular (1)
Pneumonia (1)
Oedema (1)
Rash Pruritic (1)
Renal Failure (1)
Vomiting (1)
Rhabdomyolysis (1)
Renal Failure Acute (1)
Monoparesis (1)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

Burinex Side Effects Reported to FDA

The following Burinex reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.


The appearance of Burinex on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.
Rash Pruritic, Rash Macular, Pneumonia
This is a report of a 84-year-old female patient (weight: NA) from GERMANY, suffering from the following symptoms/conditions: NA, who was treated with Burinex (bumetanide) (tablets) ( (bumetanide)) (dosage: NA, start time: Jun 09, 2010), combined with:
  • Paralief (paracetamol) (paracetamol)
  • Digoxin
  • Emcor (bisoprolol Fumarate) (5 Milligram, Tablets) (bisoprolol Fumarat
  • Seroquel (25 Mg (25 Mg, 1 In 1 D); 50 Mg (25 Mg, 2 In 1 D), Oral)
  • Seroquel (25 Mg (25 Mg, 1 In 1 D); 50 Mg (25 Mg, 2 In 1 D), Oral)
  • Folic Acid
  • Tritace (ramipril) (ramipril)
  • Anxicalm (diazepam) (diazepam)
and developed a serious reaction and side effect(s). The consumer presented with:
  • Rash Pruritic
  • Rash Macular
  • Pneumonia
which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Burinex (bumetanide) (tablets) ( (bumetanide)) treatment in female patients, resulting in rash pruritic side effect. The patient was hospitalized.

Lactic Acidosis, Myocardial Infarction, Hypovolaemic Shock, Renal Failure
This report suggests a potential Burinex Lactic Acidosis, Myocardial Infarction, Hypovolaemic Shock, Renal Failure side effect(s) that can have serious consequences. A 81-year-old female patient (weight: NA) from GERMANY was diagnosed with the following symptoms/conditions: cardiac failure,type 2 diabetes mellitus and used Burinex (dosage: 1df=4mg Plus 2mg) starting NS. Soon after starting Burinex the patient began experiencing various side effects, including:
  • Lactic Acidosis
  • Myocardial Infarction
  • Hypovolaemic Shock
  • Renal Failure
Drugs used concurrently:
  • Glucophage
  • Valsartan And Hydrochlorothiazide (1df=160mg/25mg)
Although Burinex demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as lactic acidosis, may still occur.

Hyponatraemia, Blood Osmolarity Decreased, Hypokalaemia
This Hyponatraemia, Blood Osmolarity Decreased, Hypokalaemia problem was reported by a health professional from DENMARK. A 72-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: cardiac disorder. On NS this consumer started treatment with Burinex (bumetanide) (dosage: 1 Mg (1 Mg, 1 In 1 D),). The following drugs were being taken at the same time:
  • Lamictal
  • Spirix (spironolactone) (25 Mg (25 Mg, 1 In 1 D);)
  • Abilify (10 Mg (10 Mg, 1 In 1 D);)
  • Warfarin Sodium
  • Escitalopram Oxalate (20 Mg (20 Mg, 1 In 1 D),)
When commencing Burinex (bumetanide), the patient experienced the following unwanted symptoms/side effects:
  • Hyponatraemia
  • Blood Osmolarity Decreased
  • Hypokalaemia
The patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as hyponatraemia, may become evident only after a product is in use by the general population.

Rhabdomyolysis, Monoparesis
This is a report of a 54-year-old male patient (weight: NA) from NORWAY. The patient developed the following symptoms/conditions: NA and was treated with Burinex (dosage: NA) starting Feb 01, 2010. Concurrently used drugs:
  • Cordarone (Iv Then Oral)
  • Metformin Hcl
  • Cipralex
  • Digitoxin Tab
  • Zanidip
  • Diovan
  • Simvastatin (40-80mg-daily-oral)
Soon after that, the consumer experienced the following side effects:
  • Rhabdomyolysis
  • Monoparesis
The patient was hospitalized. This opens a possibility that Burinex treatment could cause the above reactions, including rhabdomyolysis, and some male subjects may be more susceptible.


Blood Creatinine Increased, Constipation, Hypokalaemia, Ileus, Renal Failure Acute, Vomiting
A 86-year-old male patient (weight: NA) from FRANCE with the following symptoms/conditions: NA started Burinex treatment (dosage: 10 Mg/day) on Aug 10, 2006. Soon after starting Burinex treatment, the subject experienced various side effects, including:
  • Blood Creatinine Increased
  • Constipation
  • Hypokalaemia
  • Ileus
  • Renal Failure Acute
  • Vomiting
Concurrently used drugs:
  • Mono-tildiem
  • Hyperium
  • Esidrix (25 Mg, Qd)
The patient was hospitalized. This finding indicates that some male patients could be more vulnerable to Burinex.

Diabetes Mellitus Inadequate Control, Oedema, Weight Increased
A 17-year-old female patient from (weight: NA) experienced symptoms, such as: NA and was treated with Burinex(dosage: 1 Unk, Qd). The treatment was initiated on Sep 26, 2005. After that a consumer reported the following side effect(s):
  • Diabetes Mellitus Inadequate Control
  • Oedema
  • Weight Increased
Concurrently used drugs, which potentially could have contributed to side effect(s) or affected Burinex efficacy:
  • Novorapid Penfill (22+20+18)
  • Novorapid Penfill (23 Iu, Qd)
  • Novolog Mix 70/30 (18+14+14)
  • Lantus (26 Iu, Qd)
  • Lantus (16 Iu, Qd)
  • Dichlotride (50 Mg, Qd)
  • Acarbose (2-3)
  • Glucophage (3)
The patient was hospitalized.



Keep Track of Side Effects

Note Your Observations

It is really important to keep of your symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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    Burinex Safety Alerts, Active Ingredients, Usage Information

    More About Burinex

    Side Effects reported to FDA: 6

    Burinex safety alerts: No

    Reported deaths: 1

    Reported hospitalizations: 3

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