Common Carbocaine Side Effects


The most commonly reported Carbocaine side effects (click to view or check a box to report):

Overdose (7)
Dysphonia (6)
Dysphagia (6)
Dyspnoea (5)
Hypotension (5)
Shock (5)
Cardiac Arrest (4)
Bradycardia (4)
Tongue Paralysis (4)
Hypertension (4)
Convulsion (3)
Laryngeal Oedema (3)
Hypoaesthesia (3)
Tachycardia (3)
Nausea (3)
Anxiety (3)
Dizziness (3)
Hyperhidrosis (2)
Hypersensitivity (2)
Loss Of Consciousness (2)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Carbocaine Side Effects Reported to FDA



Carbocaine Side Effect Report#9771821
Throat Irritation, Chest Pain, Dyspnoea, Pallor, Respiratory Distress, Hypertension
This is a report of a 80-year-old male patient (weight: NA) from US, suffering from the following health symptoms/conditions: local anaesthesia, who was treated with Carbocaine 3% (dosage: NA, start time:
Apr 15, 2013), combined with:
  • Benzocaine
and developed a serious reaction and side effect(s): Throat Irritation, Chest Pain, Dyspnoea, Pallor, Respiratory Distress, Hypertension after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Carbocaine 3% treatment in male patients, resulting in Throat Irritation side effect.
Carbocaine Side Effect Report#9632053
Cerebral Infarction
This report suggests a potential Carbocaine Cerebral Infarction side effect(s) that can have serious consequences. A 53-year-old male patient (weight: NA) from JP was diagnosed with the following symptoms/conditions: nerve block and used Carbocaine (dosage: NA) starting NS. After starting Carbocaine the patient began experiencing various side effects, including: Cerebral InfarctionAdditional drugs used concurrently: NA.The patient was hospitalized. Although Carbocaine demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Cerebral Infarction, may still occur.
Carbocaine Side Effect Report#9539628
Stress Cardiomyopathy, Blood Pressure Increased, Heart Rate Increased
This Stress Cardiomyopathy problem was reported by a health professional from JP. A 75-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: epidural anaesthesia,induction and maintenance of anaesthesia. On NS this consumer started treatment with Carbocaine (dosage: NA). The following drugs were being taken at the same time:
  • Diprivan
  • Anapeine
  • Remifentanil
  • Morphine Hydrochloride
  • Rocuronium
When using Carbocaine, the patient experienced the following unwanted symptoms/side effects: Stress Cardiomyopathy, Blood Pressure Increased, Heart Rate IncreasedAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Stress Cardiomyopathy, may become evident only after a product is in use by the general population.
Carbocaine Side Effect Report#9525364
Respiratory Arrest, Blood Pressure Decreased, Bradycardia, Nausea, Delayed Recovery From Anaesthesia, Off Label Use
This Respiratory Arrest side effect was reported by a health professional from JP. A 40-year-old female patient (weight:NA) experienced the following symptoms/conditions: epidural anaesthesia,maintenance of anaesthesia.The patient was prescribed Carbocaine (drug dosage: NA), which was initiated on NS. Concurrently used drugs:
  • Propofol
  • Fentanyl
  • Remifentanil
  • Thiamylal
  • Rocuronium
  • Sevoflurane
.After starting to take Carbocaine the consumer reported adverse symptoms, such as: Respiratory Arrest, Blood Pressure Decreased, Bradycardia, Nausea, Delayed Recovery From Anaesthesia, Off Label UseThese side effects may potentially be related to Carbocaine.
Carbocaine Side Effect Report#9290956
Accidental Overdose, Confusional State, Depressed Level Of Consciousness, Tachycardia, Hypertension
This is a report of a 52-year-old female patient (weight: NA) from FR, suffering from the following health symptoms/conditions: nerve block,migraine, who was treated with Carbocaine (dosage: NA, start time:
Sep 27, 2012), combined with:
  • Bisoprolol
and developed a serious reaction and side effect(s): Accidental Overdose, Confusional State, Depressed Level Of Consciousness, Tachycardia, Hypertension after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Carbocaine treatment in female patients, resulting in Accidental Overdose side effect. The patient was hospitalized.
Carbocaine Side Effect Report#9285499
Throat Irritation, Chest Pain, Dyspnoea, Emotional Distress
This report suggests a potential Carbocaine Throat Irritation side effect(s) that can have serious consequences. A 80-year-old male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: anaesthesia and used Carbocaine (dosage: 1.7 Ml X 2 = 3.4 Ml Dental) starting
Apr 15, 2013. After starting Carbocaine the patient began experiencing various side effects, including: Throat Irritation, Chest Pain, Dyspnoea, Emotional DistressAdditional drugs used concurrently: NA. Although Carbocaine demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Throat Irritation, may still occur.
Carbocaine Side Effect Report#9275218
Hypersensitivity, Anxiety
This Hypersensitivity problem was reported by a health professional from US. A 44-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: local anaesthesia. On
Mar 04, 2013 this consumer started treatment with Carbocaine (dosage: 1 Df Toal Dental). The following drugs were being taken at the same time:
  • Benzocaine
When using Carbocaine, the patient experienced the following unwanted symptoms/side effects: Hypersensitivity, AnxietyThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Hypersensitivity, may become evident only after a product is in use by the general population.
Carbocaine Side Effect Report#9257071
Hyperhidrosis, Dizziness
This Hyperhidrosis side effect was reported by a physician from US. A 39-year-old female patient (weight:NA) experienced the following symptoms/conditions: local anaesthesia.The patient was prescribed Carbocaine (drug dosage: Dental), which was initiated on NS. Concurrently used drugs: NA..After starting to take Carbocaine the consumer reported adverse symptoms, such as: Hyperhidrosis, DizzinessThese side effects may potentially be related to Carbocaine.
Carbocaine Side Effect Report#9257065
Malaise, Dizziness, Hyperhidrosis
This is a report of a 33-year-old male patient (weight: NA) from US, suffering from the following health symptoms/conditions: local anaesthesia, who was treated with Carbocaine (dosage: 3 Cartridges Dental, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Malaise, Dizziness, Hyperhidrosis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Carbocaine treatment in male patients, resulting in Malaise side effect.
Carbocaine Side Effect Report#8999317
Pruritus, Erythema
This report suggests a potential Carbocaine Pruritus side effect(s) that can have serious consequences. A 72-year-old female patient (weight: NA) from FR was diagnosed with the following symptoms/conditions: local anaesthesia and used Carbocaine (dosage: NA) starting
Oct 11, 2012. After starting Carbocaine the patient began experiencing various side effects, including: Pruritus, ErythemaAdditional drugs used concurrently:
  • Perfalgan
  • Midazolam
  • Cefamandol
  • Ketamine
The patient was hospitalized. Although Carbocaine demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Pruritus, may still occur.
Carbocaine Side Effect Report#8902648
Dyskinesia, Delayed Recovery From Anaesthesia, Pyrexia
This Dyskinesia problem was reported by a health professional from JP. A 74-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: nerve block,anaesthesia,perioperative analgesia. On
Oct 29, 2012 this consumer started treatment with Carbocaine (dosage: 40ml). The following drugs were being taken at the same time:
  • Propofol (5ml/hr)
  • Anapeine (10mg/ml/3ml)
  • Anapeine (3 Ml)
  • Anapeine (2 Ml)
  • Anapeine (8 Ml)
  • Anapeine (4 Ml)
  • Dormicum
  • Ketamine Hydrochloride
When using Carbocaine, the patient experienced the following unwanted symptoms/side effects: Dyskinesia, Delayed Recovery From Anaesthesia, PyrexiaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Dyskinesia, may become evident only after a product is in use by the general population.
Carbocaine Side Effect Report#8645605
Laryngeal Oedema, Cardiac Arrest, Ventricular Tachycardia, Anaphylactic Shock
This Laryngeal Oedema side effect was reported by a physician from FR. A 23-year-old female patient (weight:NA) experienced the following symptoms/conditions: anaesthesia.The patient was prescribed Carbocaine (drug dosage: NA), which was initiated on
May 30, 2012. Concurrently used drugs:
  • Naropeine
  • Cefazoline
  • Hypnovel
  • Sufenta (5, Once/single Administration)
  • Betadine
  • Birth Control Pill
.After starting to take Carbocaine the consumer reported adverse symptoms, such as: Laryngeal Oedema, Cardiac Arrest, Ventricular Tachycardia, Anaphylactic ShockThese side effects may potentially be related to Carbocaine.
Carbocaine Side Effect Report#8373809-X
Hypotension, Shock, Bronchospasm
This is a report of a 55-year-old male patient (weight: NA) from France, suffering from the following health symptoms/conditions: local anaesthesia, who was treated with Carbocaine (dosage: Once/single Administration, start time:
Jan 17, 2012), combined with:
  • Propofol (Once/single Administration)
  • Celocurine (Once/single Administration)
  • Xylocaine (Once/single Administration)
  • Sufentanil Citrate (Once/single Administration)
  • Cefazolin (Once/single Administration)
and developed a serious reaction and side effect(s): Hypotension, Shock, Bronchospasm after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Carbocaine treatment in male patients, resulting in Hypotension side effect.
Carbocaine Side Effect Report#8371301-X
Bradycardia, Hypertension, Overdose, Nausea
This report suggests a potential Carbocaine Bradycardia side effect(s) that can have serious consequences. A 94-year-old female patient (weight: NA) from France was diagnosed with the following symptoms/conditions: nerve block and used Carbocaine (dosage: NA) starting NS. After starting Carbocaine the patient began experiencing various side effects, including: Bradycardia, Hypertension, Overdose, NauseaAdditional drugs used concurrently: NA.The patient was hospitalized. Although Carbocaine demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Bradycardia, may still occur.
Carbocaine Side Effect Report#8255707-5
Dysgeusia, Ageusia, Anosmia
This Dysgeusia problem was reported by a health professional from United States. A 42-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: artificial crown procedure,endodontic procedure. On
Aug 11, 2011 this consumer started treatment with Carbocaine (dosage: NA). The following drugs were being taken at the same time:
  • Septocaine
When using Carbocaine, the patient experienced the following unwanted symptoms/side effects: Dysgeusia, Ageusia, AnosmiaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Dysgeusia, may become evident only after a product is in use by the general population.
Carbocaine Side Effect Report#8038017-0
Corneal Staining
This Corneal Staining side effect was reported by a physician from France. A 59-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Carbocaine (drug dosage: NA), which was initiated on
Nov 09, 2011. Concurrently used drugs:
  • Betadine
  • Tropicamide
  • Indomethacin
  • Azithromycin
  • Irbesartan And Hydrochlorothiazide
  • Metformin Hcl
  • Benoxinate Hydrochloride
  • Levofloxacin
.After starting to take Carbocaine the consumer reported adverse symptoms, such as: Corneal StainingThese side effects may potentially be related to Carbocaine.
Carbocaine Side Effect Report#8021828-5
Uterine Perforation
This is a report of a 26-year-old female patient (weight: NA) from United States, suffering from the following health symptoms/conditions: NA, who was treated with Carbocaine (dosage: 35cc, start time: NS), combined with:
  • Mirena
and developed a serious reaction and side effect(s): Uterine Perforation after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Carbocaine treatment in female patients, resulting in Uterine Perforation side effect.
Carbocaine Side Effect Report#7989234-7
Fall, Hypoaesthesia
This report suggests a potential Carbocaine Fall side effect(s) that can have serious consequences. A female patient (weight: NA) from United States was diagnosed with the following symptoms/conditions: artificial crown procedure and used Carbocaine (dosage: Injection Into Gums Spring) starting
Jan 01, 2009. After starting Carbocaine the patient began experiencing various side effects, including: Fall, HypoaesthesiaAdditional drugs used concurrently: NA. Although Carbocaine demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Fall, may still occur.
Carbocaine Side Effect Report#7883384-1
Anxiety, Tremor, Myocardial Infarction, Asthenia
This Anxiety problem was reported by a health professional from United States. A 85-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: local anaesthesia. On
Jul 28, 2011 this consumer started treatment with Carbocaine W/ Neo-cobefrin (dosage: NA). The following drugs were being taken at the same time: NA. When using Carbocaine W/ Neo-cobefrin, the patient experienced the following unwanted symptoms/side effects: Anxiety, Tremor, Myocardial Infarction, AstheniaThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Anxiety, may become evident only after a product is in use by the general population.
Carbocaine Side Effect Report#7191404-5
Anxiety, Disorientation, Dizziness, Dyspnoea, Heart Rate Increased, Hypertension, Hypoaesthesia, Pulse Pressure Decreased, Somnolence
This Anxiety side effect was reported by a health professional from United States. A 40-year-old female patient (weight:NA) experienced the following symptoms/conditions: dental operation.The patient was prescribed Carbocaine Without Epi (mepivacaine) (drug dosage: Injection), which was initiated on
Nov 14, 2010. Concurrently used drugs: NA..After starting to take Carbocaine Without Epi (mepivacaine) the consumer reported adverse symptoms, such as: Anxiety, Disorientation, Dizziness, Dyspnoea, Heart Rate Increased, Hypertension, Hypoaesthesia, Pulse Pressure Decreased, SomnolenceThese side effects may potentially be related to Carbocaine Without Epi (mepivacaine).
Carbocaine Side Effect Report#6848408-9
Cardiac Arrest, Convulsion, Tachycardia
This is a report of a 56-year-old female patient (weight: NA) from France, suffering from the following health symptoms/conditions: local anaesthesia, who was treated with Carbocaine (dosage: 2 %, Single Administration, start time:
Jul 12, 2009), combined with:
  • Naropin (7.5 Mg/ml, Single Administration)
and developed a serious reaction and side effect(s): Cardiac Arrest, Convulsion, Tachycardia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Carbocaine treatment in female patients, resulting in Cardiac Arrest side effect.
Carbocaine Side Effect Report#6715014-6
Cardiac Failure, Dyspnoea, Multi-organ Failure
This report suggests a potential Carbocaine Cardiac Failure side effect(s) that can have serious consequences. A 78-year-old female patient (weight: NA) from France was diagnosed with the following symptoms/conditions: NA and used Carbocaine (dosage: NA) starting NS. After starting Carbocaine the patient began experiencing various side effects, including: Cardiac Failure, Dyspnoea, Multi-organ FailureAdditional drugs used concurrently:
  • Metformin
  • Glyburide
  • Kardegic
  • Crestor
  • Mediatensyl
  • Amlor
  • Insulin
  • Seasonal Flu Vaccine
Although Carbocaine demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Cardiac Failure, may still occur.
Carbocaine Side Effect Report#6456694-2
Aphasia, Hypersensitivity, Musculoskeletal Disorder, Post Procedural Complication, Syncope
This Aphasia problem was reported by a health professional from United States. A 40-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Sep 01, 2009 this consumer started treatment with Carbocaine (dosage: Frequency Once, Injection). The following drugs were being taken at the same time: NA. When using Carbocaine, the patient experienced the following unwanted symptoms/side effects: Aphasia, Hypersensitivity, Musculoskeletal Disorder, Post Procedural Complication, SyncopeAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Aphasia, may become evident only after a product is in use by the general population.
Carbocaine Side Effect Report#6265659-5
Dyspnoea, Feeling Hot, Hypotension, Nausea, Vomiting
This Dyspnoea side effect was reported by a consumer or non-health professional from United States. A 11-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Carbocaine (drug dosage: NA), which was initiated on NS. Concurrently used drugs: NA..After starting to take Carbocaine the consumer reported adverse symptoms, such as: Dyspnoea, Feeling Hot, Hypotension, Nausea, VomitingThese side effects may potentially be related to Carbocaine.
Carbocaine Side Effect Report#5833624-5
Dyskinesia, Loss Of Consciousness, Muscle Rigidity
This is a report of a female patient (weight: NA) from France, suffering from the following health symptoms/conditions: local anaesthesia, who was treated with Carbocaine (dosage: NA, start time:
Apr 03, 2008), combined with: NA. and developed a serious reaction and side effect(s): Dyskinesia, Loss Of Consciousness, Muscle Rigidity after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Carbocaine treatment in female patients, resulting in Dyskinesia side effect. The patient was hospitalized.


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The appearance of Carbocaine on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

What are common Carbocaine Side Effects for Women?

Women Side Effects Reports
Overdose 6
Anxiety 3
Dysphagia 3
Dysphonia 3
Dyspnoea 3
Hypertension 3
Hypoaesthesia 3
Laryngeal Oedema 3
Nausea 3
Tachycardia 3

What are common Carbocaine Side Effects for Men?

Men Side Effects Reports
Shock 5
Dysphagia 3
Dysphonia 3
Hypotension 3
Bradycardia 2
Cardiac Arrest 2
Chest Pain 2
Dyspnoea 2
Pneumonia 2
Throat Irritation 2

Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Carbocaine reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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    Carbocaine Safety Alerts, Active Ingredients, Usage Information

    NDC 0409-1036
    Type HUMAN PRESCRIPTION DRUG
    Proprietary Name Carbocaine
    Name Mepivacaine Hydrochloride
    Dosage Form INJECTION, SOLUTION
    Route EPIDURAL; INFILTRATION
    On market since 20100308
    Labeler Hospira, Inc.
    Active Ingredient(s) MEPIVACAINE HYDROCHLORIDE
    Strength(s) 10
    Unit(s) mg/mL
    Pharma Class Amide Local Anesthetic [EPC],Amides [Chemical/Ingredient],Local Anesthesia [PE]

    Carbocaine Dosage, Warnings, Usage.

    Side Effects reported to FDA: 43

    Carbocaine safety alerts: No

    Reported deaths: 2

    Reported hospitalizations: 16

    Latest Carbocaine clinical trials

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