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Ciprofloxacin Side Effects

Common Ciprofloxacin Side Effects


The most commonly reported Ciprofloxacin side effects (click to view or check a box to report):

Arthralgia (550)
Pain In Extremity (389)
Tendonitis (277)
Diarrhoea (274)
Pyrexia (260)
Renal Failure Acute (240)
Tendon Pain (237)
Dizziness (236)
Headache (234)
Anxiety (233)
Myalgia (229)
Nausea (225)
Pain (225)
Paraesthesia (219)
Insomnia (208)
Fatigue (204)
Rash (202)
Gait Disturbance (195)
Confusional State (187)
Tendon Rupture (174)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

Ciprofloxacin Side Effects Reported to FDA

The following Ciprofloxacin reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.


The appearance of Ciprofloxacin on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.
Heart Rate Increased, Tremor, Paraesthesia, Hypoaesthesia
This is a report of a 48-year-old female patient (weight: NA) from US, suffering from the following symptoms/conditions: diarrhoea infectious, who was treated with Ciprofloxacin Hcl (dosage: 1 Pill Twice Daily Taken By Mouth, start time: Mar 07, 2014), combined with: NA. and developed a serious reaction and side effect(s). The consumer presented with:
  • Heart Rate Increased
  • Tremor
  • Paraesthesia
  • Hypoaesthesia
which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Ciprofloxacin Hcl treatment in female patients, resulting in heart rate increased side effect.

Septic Shock
This report suggests a potential Ciprofloxacin Injection Ip Septic Shock side effect(s) that can have serious consequences. A 38-year-old male patient (weight: NA) from IN was diagnosed with the following symptoms/conditions: mycobacterium tuberculosis complex test positive and used Ciprofloxacin Injection Ip (dosage: NA) starting NS. Soon after starting Ciprofloxacin Injection Ip the patient began experiencing various side effects, including:
  • Septic Shock
Drugs used concurrently:
  • Tacrolimus
  • Mycophenolate Mofetil
  • Mycophenolate Mofetil
  • Prednisolone
  • Amoxicillin+clavulanic Acid
  • Piperacillin Plus Tazobactam
  • Metronidazole
  • Amikacin
Although Ciprofloxacin Injection Ip demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as septic shock, may still occur.

Abdominal Pain Upper, Hot Flush, Myalgia, Neuropathy Peripheral, Feeling Cold
This Abdominal Pain Upper, Hot Flush, Myalgia, Neuropathy Peripheral, Feeling Cold problem was reported by a consumer or non-health professional from US. A 65-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: urinary tract infection. On Mar 06, 2014 this consumer started treatment with Ciprofloxacin Hcl (dosage: 1 Pill Twice Daily). The following drugs were being taken at the same time: NA. When commencing Ciprofloxacin Hcl, the patient experienced the following unwanted symptoms/side effects:
  • Abdominal Pain Upper
  • Hot Flush
  • Myalgia
  • Neuropathy Peripheral
  • Feeling Cold
Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as abdominal pain upper, may become evident only after a product is in use by the general population.

Sepsis, Pathogen Resistance, Septic Shock, Thrombocytopenia, Cerebrovascular Accident
This is a report of a 49-year-old female patient (weight: NA) from SG. The patient developed the following symptoms/conditions: bacteraemia and was treated with Ciprofloxacin (dosage: Unk) starting NS. Concurrently used drugs:
  • Piperacillin W/tazobactam (Unk)
  • Piperacillin W/tazobactam
  • Piperacillin W/tazobactam
  • Vancomycin (Unk)
  • Rifampicin (150 Mg, Bid)
  • Minocycline (100 Mg, Bid)
  • Levofloxacin (500 Mg/day)
Soon after that, the consumer experienced the following side effects:
  • Sepsis
  • Pathogen Resistance
  • Septic Shock
  • Thrombocytopenia
  • Cerebrovascular Accident
The patient was hospitalized. This opens a possibility that Ciprofloxacin treatment could cause the above reactions, including sepsis, and some female subjects may be more susceptible.


Neuropathy Peripheral, Paraesthesia, Hypoaesthesia, Skin Burning Sensation, Vision Blurred, Depression, Poor Quality Sleep, Memory Impairment, Pain In Extremity
A 63-year-old male patient (weight: NA) from DE with the following symptoms/conditions: prostatitis started Ciprofloxacin treatment (dosage: NA) on NS. Soon after starting Ciprofloxacin treatment, the subject experienced various side effects, including:
  • Neuropathy Peripheral
  • Paraesthesia
  • Hypoaesthesia
  • Skin Burning Sensation
  • Vision Blurred
  • Depression
  • Poor Quality Sleep
  • Memory Impairment
  • Pain In Extremity
Concurrently used drugs:
  • Levofloxacin
This finding indicates that some male patients could be more vulnerable to Ciprofloxacin.

Asthenia, Muscular Weakness, Feeling Abnormal
A 83-year-old female patient from US (weight: NA) experienced symptoms, such as: local swelling,blister and was treated with Ciprofloxacin Hcl(dosage: By Mouth). The treatment was initiated on Nov 20, 2013. After that a consumer reported the following side effect(s):
  • Asthenia
  • Muscular Weakness
  • Feeling Abnormal
Concurrently used drugs, which potentially could have contributed to side effect(s) or affected Ciprofloxacin Hcl efficacy: NA.

Gait Disturbance, Tendon Pain, Skin Discolouration
In this report, Ciprofloxacin Hcl was administered for the following condition: infected dermal cyst.A 60-year-old female consumer from US (weight: NA) started Ciprofloxacin Hcl treatment (dosage: NA) on Feb 24, 2014.Sometime after starting the treatment, the patient complained of the following side effect(s):
  • Gait Disturbance
  • Tendon Pain
  • Skin Discolouration
A possible interaction with other drugs could have contributed to this reaction: NA.Establishing a causal relationship between a specific drug and consumer's side effects is complex, but it is possible that in this report Ciprofloxacin Hcl treatment could be related to the listed above side effect(s).

Headache, Hyperaesthesia
This is a report of the following Ciprofloxacin side effect(s):
  • Headache
  • Hyperaesthesia
A 74-year-old female patient from US (weight: NA) presented with the following condition: cystitis and received a treatment with Ciprofloxacin (dosage: 14 Took 5 Pills) starting: Feb 08, 2014.The following concurrently used drugs could have generated interactions:
  • Metoprolol
  • Levothyroxine
  • Aspirin
  • Cranberry
  • Vitamin C
  • Fish Oil
  • Coq10
  • Vitamin D3
This report suggests that a Ciprofloxacin treatment could be associated with the listed above side effect(s).

Dermatitis Exfoliative, Gastrointestinal Haemorrhage, Hepatic Failure, Renal Failure, Sensitisation, Rash Pruritic
This Ciprofloxacin report was submitted by a 54-year-old male consumer from ES (weight: NA). The patient was diagnosed with: wound infection and Ciprofloxacin was administered (dosage: Unk) starting: 200906. The consumer developed a set of symptoms:
  • Dermatitis Exfoliative
  • Gastrointestinal Haemorrhage
  • Hepatic Failure
  • Renal Failure
  • Sensitisation
  • Rash Pruritic
Other drugs used simultaneously: NA.The patient was hospitalized.Those unexpected symptoms could be linked to a Ciprofloxacin treatment, however establishing a potential drug-safety problem requires a more detailed clinical analysis.

Paraesthesia
This is a report of a possible correlation between Ciprofloxacin 250mg use and the following symptoms/side effect(s):
  • Paraesthesia
which could contribute to an assessment of Ciprofloxacin 250mg risk profile.A 49-year-old female consumer from US (weight: NA) was suffering from urinary tract infection and was treated with Ciprofloxacin 250mg (dosage: Ciprofloxacin Hcl Twice Daily Taken By Mouth) starting Mar 03, 2014.Other concurrent medications: NA.

Haematochezia, Vomiting
A 73-year-old female patient from GB (weight: NA) presented with the following symptoms: NA and after a treatment with Ciprofloxacin (ciprofloxacin) (dosage: 250 Mg, 2 In 1 D) experienced the following side effect(s):
  • Haematochezia
  • Vomiting
The treatment was started on NS. Ciprofloxacin (ciprofloxacin) was used in combination with the following drugs:
  • Metronidazole
This report could alert potential Ciprofloxacin (ciprofloxacin) consumers.

Tendon Pain, Muscle Spasms, Gait Disturbance
In this report, a 43-year-old male patient from GB (weight: NA) was affected by a possible Ciprofloxacin side effect.The patient was diagnosed with prostatitis. After a treatment with Ciprofloxacin (dosage: 2 X 500 Day, start date: NS), the patient experienced the following side effect(s):
  • Tendon Pain
  • Muscle Spasms
  • Gait Disturbance
The following simultaneously used drugs could have led to this reaction: NA.The findings here stress that side effects should be taken into consideration when evaluating a Ciprofloxacin treatment.

Dizziness, Sensory Disturbance, Cough, Palpitations, Vertigo, Movement Disorder, Heart Rate Irregular, Aortic Aneurysm, Cardiomegaly
This is a report of a male patient from US (weight: NA), who used Ciprofloxacin, 500 Mg, West-ward (dosage: Taken By Mouth) for a treatment of urinary tract infection. After starting a treatment on NS, the patient experienced the following side effect(s):
  • Dizziness
  • Sensory Disturbance
  • Cough
  • Palpitations
  • Vertigo
  • Movement Disorder
  • Heart Rate Irregular
  • Aortic Aneurysm
  • Cardiomegaly
The following drugs could possibly have interacted with the Ciprofloxacin, 500 Mg, West-ward treatment NA.The patient was hospitalized and became disabled.Taken together, these observations suggest that a Ciprofloxacin, 500 Mg, West-ward treatment could be related to side effect(s), such as Dizziness, Sensory Disturbance, Cough, Palpitations, Vertigo, Movement Disorder, Heart Rate Irregular, Aortic Aneurysm, Cardiomegaly.

Arthralgia, Gait Disturbance, Feeling Abnormal
This arthralgia side effect was reported by a consumer or non-health professional from US. A 58-year-old female patient (weight:NA) experienced the following symptoms/conditions: urinary tract infection. The patient was prescribed Ciprofloxacin (dosage: 2 Pills Daily Twice Daily Taken By Mouth), which was started on Feb 17, 2014. Concurrently used drugs: NA. When starting to take Ciprofloxacin the consumer reported the following symptoms:
  • Arthralgia
  • Gait Disturbance
  • Feeling Abnormal
These side effects may potentially be related to Ciprofloxacin.

Dizziness, Hypoaesthesia, Panic Attack, Paraesthesia, Restlessness
This is a Ciprofloxacin side effect report of a 42-year-old male patient (weight:NA) from DE, suffering from the following symptoms/conditions: urinary tract infection, who was treated with Ciprofloxacin (dosage:NA, start time: Sep 05, 2013), combined with: NA., and developed a serious reaction and a dizziness side effect. The patient presented with:
  • Dizziness
  • Hypoaesthesia
  • Panic Attack
  • Paraesthesia
  • Restlessness
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Ciprofloxacin treatment in male patients suffering from urinary tract infection, resulting in dizziness.

Fatigue, Neuropathy Peripheral, Pain In Extremity, Burnout Syndrome
This report suggests a potential Ciprofloxacin fatigue side effect(s) that can have serious consequences. A 55-year-old female patient from GB (weight:NA) was diagnosed with the following health condition(s): urinary tract infection and used Ciprofloxacin (dosage: 250 Mg, Bid) starting Mar 21, 2009. Soon after starting Ciprofloxacin the patient began experiencing various side effects, including:
  • Fatigue
  • Neuropathy Peripheral
  • Pain In Extremity
  • Burnout Syndrome
Drugs used concurrently:
  • Atenolol (Unk)
  • Buscopan (Unk)
  • Diazepam (Unk)
The patient was hospitalized and became disabled. Although Ciprofloxacin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as fatigue, may still occur.

Burnout Syndrome, Fatigue, Neuropathy Peripheral, Pain In Extremity
This burnout syndrome problem was reported by a consumer or non-health professional from GB. A 55-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): urinary tract infection.On Mar 21, 2009 a consumer started treatment with Ciprofloxacin (dosage: 250 Mg, Bid). The following drugs/medications were being taken at the same time:
  • Atenolol
  • Buscopan
  • Diazepam
When commencing Ciprofloxacin, the patient experienced the following unwanted symptoms /side effects:
  • Burnout Syndrome
  • Fatigue
  • Neuropathy Peripheral
  • Pain In Extremity
The patient was hospitalized and became disabled. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as burnout syndrome, may become evident only after a product is in use by the general population.

Hepatitis Acute
This is a Ciprofloxacin side effect report of a 41-year-old female patient (weight: NA) from US. The patient developed the following symptoms/conditions: streptococcal urinary tract infection and was treated with Ciprofloxacin (dosage: NA) starting NS. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
  • Hepatitis Acute
The patient was hospitalized. This opens a possibility that Ciprofloxacin could cause hepatitis acute and that some female patients may be more susceptible.

Burnout Syndrome, Fatigue, Neuropathy Peripheral, Pain In Extremity
A 55-year-old female patient (weight: NA) from GB with the following symptoms: urinary tract infection started Ciprofloxacin treatment (dosage: 250 Mg Bid) on Mar 21, 2009. Soon after starting Ciprofloxacin treatment, the consumer experienced several side effects, including:
  • Burnout Syndrome
  • Fatigue
  • Neuropathy Peripheral
  • Pain In Extremity
. Concurrently used drugs:
  • Atenolol
  • Buscopan
  • Diazepam
The patient was hospitalized and became disabled. This finding indicates that some patients can be more vulnerable to developing Ciprofloxacin side effects, such as burnout syndrome.

Pain In Extremity
This pain in extremity side effect was reported by a consumer or non-health professional from US. A female patient (weight:NA) experienced the following symptoms/conditions: bacterial infection.The patient was prescribed Ciprofloxacin Hcl (dosage: NA), which was started on Oct 04, 2013. Concurrently used drugs:
  • Tramadol
  • Rabain
  • Daily Vitamin
.When starting to take Ciprofloxacin Hcl the consumer reported symptoms, such as:
  • Pain In Extremity
These side effects may potentially be related to Ciprofloxacin Hcl.

Pruritus, Abdominal Distension, Erythema, Flushing, Local Swelling, Pulmonary Thrombosis, Dizziness, Bone Pain
This is a report of a 65-year-old female patient (weight: NA) from AU, suffering from the following symptoms/conditions: urinary tract infection, who was treated with Ciprofloxacin (dosage: NA, start time: Dec 04, 2013), combined with:
  • Endone (oxycodone Hydrochloride)
  • Ciprofloxacin (ciprofloxacin)
and developed a serious reaction and side effect(s). The consumer presented with:
  • Pruritus
  • Abdominal Distension
  • Erythema
  • Flushing
  • Local Swelling
  • Pulmonary Thrombosis
  • Dizziness
  • Bone Pain
which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Ciprofloxacin treatment in female patients, resulting in pruritus side effect.

Paraesthesia, Insomnia, Myalgia, Limb Discomfort, Joint Crepitation, Hypoaesthesia, Chest Pain, Middle Insomnia
This report suggests a potential Ciprofloxacin 500 Mg Cobalt Paraesthesia, Insomnia, Myalgia, Limb Discomfort, Joint Crepitation, Hypoaesthesia, Chest Pain, Middle Insomnia side effect(s) that can have serious consequences. A 62-year-old male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: epididymitis and used Ciprofloxacin 500 Mg Cobalt (dosage: 500 Mg/20 Pills ?twice Daily ?taken By Mouth) starting Feb 14, 2014. Soon after starting Ciprofloxacin 500 Mg Cobalt the patient began experiencing various side effects, including:
  • Paraesthesia
  • Insomnia
  • Myalgia
  • Limb Discomfort
  • Joint Crepitation
  • Hypoaesthesia
  • Chest Pain
  • Middle Insomnia
Drugs used concurrently: NA. Although Ciprofloxacin 500 Mg Cobalt demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as paraesthesia, may still occur.

Induration, Erythema
This Induration, Erythema problem was reported by a physician from DE. A 40-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Ciprofloxacin (dosage: 800 Milligram Daily;). The following drugs were being taken at the same time: NA. When commencing Ciprofloxacin, the patient experienced the following unwanted symptoms/side effects:
  • Induration
  • Erythema
Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as induration, may become evident only after a product is in use by the general population.

Neuropathy Peripheral, Abasia, Muscle Atrophy
This is a report of a 60-year-old male patient (weight: NA) from US. The patient developed the following symptoms/conditions: abscess drainage and was treated with Ciprofloxacin (dosage: 400 Mg ?twice Daily ?into A Vein) starting Apr 04, 2013. Concurrently used drugs: NA.Soon after that, the consumer experienced the following side effects:
  • Neuropathy Peripheral
  • Abasia
  • Muscle Atrophy
This opens a possibility that Ciprofloxacin treatment could cause the above reactions, including neuropathy peripheral, and some male subjects may be more susceptible.

Pain, Neuropathy Peripheral, Discomfort
A 53-year-old female patient (weight: NA) from US with the following symptoms/conditions: urinary tract infection started Ciprofloxacin treatment (dosage: 1 Tab) on Jan 01, 2013. Soon after starting Ciprofloxacin treatment, the subject experienced various side effects, including:
  • Pain
  • Neuropathy Peripheral
  • Discomfort
Concurrently used drugs: NA. This finding indicates that some female patients could be more vulnerable to Ciprofloxacin.

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Top 10 Ciprofloxacin Side Effects for Women

Women Side EffectsReports
Arthralgia 343
Pain In Extremity 244
Tendonitis 170
Diarrhoea 164
Pain 154
Dizziness 142
Paraesthesia 139
Nausea 135
Myalgia 132
Gait Disturbance 131

Top 10 Ciprofloxacin Side Effects for Men

Men Side EffectsReports
Arthralgia 204
Pain In Extremity 143
Pyrexia 136
Renal Failure Acute 113
Tendon Pain 108
Headache 107
Tendonitis 106
Anxiety 103
Diarrhoea 101
Rash 97

Keep Track of Side Effects

Note Your Observations

It is really important to keep of your symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


    Discuss Ciprofloxacin Side Effects

    Did You Have a Ciprofloxacin Side Effect?

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    Yes, Minor
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    How Effective is Ciprofloxacin for You?

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    Ciprofloxacin Safety Alerts, Active Ingredients, Usage Information

    NDC0069-3241
    TypeHUMAN PRESCRIPTION DRUG
    Proprietary NameCiprofloxacin
    NameCiprofloxacin
    Dosage FormINJECTION, SOLUTION, CONCENTRATE
    RouteINTRAVENOUS
    On market since20090911
    LabelerPfizer Labs, Division of Pfizer Inc
    Active Ingredient(s)CIPROFLOXACIN
    Strength(s)10
    Unit(s)mg/mL
    Pharma ClassQuinolone Antimicrobial [EPC],Quinolones [Chemical/Ingredient]

    Ciprofloxacin Dosage, Warnings, Usage.

    Side Effects reported to FDA: 6073

    Ciprofloxacin safety alerts: No

    Reported deaths: 450

    Reported hospitalizations: 1816

    Latest Ciprofloxacin clinical trials