Common Clexane Side Effects


The most commonly reported Clexane side effects (click to view or check a box to report):

Exposure During Pregnancy (61)
Pulmonary Embolism (60)
Alanine Aminotransferase Increased (51)
Aspartate Aminotransferase Increased (46)
Anaemia (41)
Hepatic Function Abnormal (33)
Liver Injury (33)
Thrombocytopenia (30)
Haematoma (23)
Death (23)
Hypotension (21)
Abortion Spontaneous (20)
Hepatitis (18)
Gamma-glutamyltransferase Increased (18)
Renal Failure (18)
Seroma (16)
Nausea (16)
Pyrexia (15)
Haemoglobin Decreased (15)
Haemorrhage (15)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Clexane Side Effects Reported to FDA



Clexane Side Effect Report#9996588
Atrial Flutter, Cardiomegaly
This is a report of a 87-year-old female patient (weight: NA) from DE, suffering from the following health symptoms/conditions: ischaemia, who was treated with Clexane (dosage: NA, start time:
Feb 25, 2013), combined with: NA. and developed a serious reaction and side effect(s): Atrial Flutter, Cardiomegaly after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Clexane treatment in female patients, resulting in Atrial Flutter side effect.
Clexane Side Effect Report#9973667
Abortion Spontaneous, Exposure During Pregnancy
This report suggests a potential Clexane Abortion Spontaneous side effect(s) that can have serious consequences. A 30-year-old female patient (weight: NA) from ZA was diagnosed with the following symptoms/conditions: prophylaxis and used Clexane (dosage: Taken To Date: Oct, 2013) starting
Oct 02, 2013. After starting Clexane the patient began experiencing various side effects, including: Abortion Spontaneous, Exposure During PregnancyAdditional drugs used concurrently: NA. Although Clexane demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Abortion Spontaneous, may still occur.
Clexane Side Effect Report#9973651
Rheumatoid Arthritis
This Rheumatoid Arthritis problem was reported by a physician from GB. A 63-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: cerebrovascular disorder,rheumatoid arthritis,hyperlipidaemia. On
Jan 23, 2014 this consumer started treatment with Clexane (dosage: NA). The following drugs were being taken at the same time:
  • Tocilizumab (Frequency: Every 4 Weekly?b2016)
  • Simvastatin
  • Simvastatin
  • Clopidogrel
  • Enalapril
  • Felodipine (Dose: 10mg (1 In 1))
  • Methotrexate
  • Folic Acid
When using Clexane, the patient experienced the following unwanted symptoms/side effects: Rheumatoid ArthritisThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Rheumatoid Arthritis, may become evident only after a product is in use by the general population.
Clexane Side Effect Report#9913929
Anaemia, Retroperitoneal Haematoma, Angina Pectoris
This Anaemia side effect was reported by a physician from ES. A 76-year-old male patient (weight:NA) experienced the following symptoms/conditions: thrombosis prophylaxis,deep vein thrombosis,ventricular tachycardia,cardiac failure congestive,hyperuricaemia,type 2 diabetes mellitus.The patient was prescribed Clexane (drug dosage: 40mg 6 To 8 March After 60 Mg / Day), which was initiated on 2011. Concurrently used drugs:
  • Sintrom (Sp)
  • Atenolol (1-0-0)
  • Enalapril (1-0-0)
  • Allopurinol (1cp)
  • Oral Antidiabetics (1-0-1)
.After starting to take Clexane the consumer reported adverse symptoms, such as: Anaemia, Retroperitoneal Haematoma, Angina PectorisThese side effects may potentially be related to Clexane. The patient was hospitalized.
Clexane Side Effect Report#9882057
Pain, Thrombosis, Oedema
This is a report of a 63-year-old female patient (weight: NA) from IT, suffering from the following health symptoms/conditions: thrombosis prophylaxis, who was treated with Clexane (dosage: NA, start time:
Oct 11, 2013), combined with:
  • Valpression (Strength: 80 Mg)
  • Lopresor (Strength: 100 Mg)
and developed a serious reaction and side effect(s): Pain, Thrombosis, Oedema after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Clexane treatment in female patients, resulting in Pain side effect.
Clexane Side Effect Report#9882055
Renal Impairment, Pre-eclampsia, Foetal Distress Syndrome, Oedema Peripheral, Exposure During Pregnancy
This report suggests a potential Clexane Renal Impairment side effect(s) that can have serious consequences. A 21-year-old female patient (weight: NA) from BR was diagnosed with the following symptoms/conditions: NA and used Clexane (dosage: NA) starting NS. After starting Clexane the patient began experiencing various side effects, including: Renal Impairment, Pre-eclampsia, Foetal Distress Syndrome, Oedema Peripheral, Exposure During PregnancyAdditional drugs used concurrently: NA.The patient was hospitalized. Although Clexane demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Renal Impairment, may still occur.
Clexane Side Effect Report#9877254
Hospitalisation, Exposure During Breast Feeding
This Hospitalisation problem was reported by a consumer or non-health professional from BR. A female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Clexane (dosage: NA). The following drugs were being taken at the same time: NA. When using Clexane, the patient experienced the following unwanted symptoms/side effects: Hospitalisation, Exposure During Breast FeedingThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Hospitalisation, may become evident only after a product is in use by the general population.
Clexane Side Effect Report#9867231
Amniotic Fluid Volume Decreased, Exposure During Pregnancy
This Amniotic Fluid Volume Decreased side effect was reported by a consumer or non-health professional from BR. A 36-year-old female patient (weight:NA) experienced the following symptoms/conditions: thrombosis prophylaxis.The patient was prescribed Clexane (drug dosage: 1 Vial Daily), which was initiated on
Feb 07, 2013. Concurrently used drugs: NA..After starting to take Clexane the consumer reported adverse symptoms, such as: Amniotic Fluid Volume Decreased, Exposure During PregnancyThese side effects may potentially be related to Clexane.
Clexane Side Effect Report#9852434
Exposure During Pregnancy
This is a report of a 34-year-old female patient (weight: NA) from BR, suffering from the following health symptoms/conditions: hypercoagulation,ill-defined disorder,prophylaxis,blood glucose abnormal,pregnancy, who was treated with Clexane (dosage: NA, start time:
Mar 31, 2013), combined with:
  • Centrum
  • Folic Acid
  • Metformin
  • Progesterone
and developed a serious reaction and side effect(s): Exposure During Pregnancy after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Clexane treatment in female patients, resulting in Foetal Death side effect.
Clexane Side Effect Report#9805804
Hypoglycaemia
This report suggests a potential Clexane Hypoglycaemia side effect(s) that can have serious consequences. A 90-year-old female patient (weight: NA) from ES was diagnosed with the following symptoms/conditions: atrial fibrillation,cardiac failure congestive,post procedural infection and used Clexane (dosage: 20mg) starting
Mar 05, 2013. After starting Clexane the patient began experiencing various side effects, including: HypoglycaemiaAdditional drugs used concurrently:
  • Furosemida (20mg/12h)
  • Cefepime (1gr/8h)
  • Teicoplanin (400mg)
  • Lormetazepam (1mg Cena)
  • Paracetamol (1gr/8h)
  • Pantoprazole (1amp)
The patient was hospitalized. Although Clexane demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Hypoglycaemia, may still occur.
Clexane Side Effect Report#9795942
Hypotension, Anaemia, Gastric Ulcer Haemorrhage, Haematemesis, Melaena
This Hypotension problem was reported by a pharmacist from IT. A 89-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: thrombosis prophylaxis. On
Apr 30, 2013 this consumer started treatment with Clexane (dosage: Strength: 4000 Iu Dose:1 Unit(s)). The following drugs were being taken at the same time:
  • Ticlopidine Hydrochloride
  • Tora-dol (Strength : 30 Mg/ml Dose:1 Unit(s))
  • Tora-dol (Dose:1 Unit(s))
  • Bisoprolol Hemifumarate (Since 6 Months?strength: 1.25 Mg)
  • Novonorm (20 Mg)
  • Lasix (Since 1 Year?strength: 25 Mg)
  • Triatec (10 Mg Divisible Tablet Dose:1 Unit(s))
  • Torvast (Strength: 10 Mg?since 6 Months)
When using Clexane, the patient experienced the following unwanted symptoms/side effects: Hypotension, Anaemia, Gastric Ulcer Haemorrhage, Haematemesis, MelaenaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Hypotension, may become evident only after a product is in use by the general population.
Clexane Side Effect Report#9790344
Cerebral Ischaemia, Haematoma
This Cerebral Ischaemia side effect was reported by a physician from CH. A 72-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Clexane (drug dosage: Form:vials), which was initiated on
Sep 05, 2013. Concurrently used drugs:
  • Sintrom I Mitis
  • Aspirin Cardio
  • Logimax
.After starting to take Clexane the consumer reported adverse symptoms, such as: Cerebral Ischaemia, HaematomaThese side effects may potentially be related to Clexane. The patient was hospitalized.
Clexane Side Effect Report#9783416
Intestinal Perforation, Rectal Haemorrhage
This is a report of a 82-year-old female patient (weight: NA) from IT, suffering from the following health symptoms/conditions: peripheral arterial occlusive disease, who was treated with Clexane (dosage: Dose-4 Iu In Million Daily, start time:
Jan 15, 2012), combined with:
  • Cardioaspirin
  • Bisoprolol Hemifumarate
  • Furosemide
  • Pantoprazole
  • Adenuric
  • Zestoretic
  • Normothen
  • Adalat
and developed a serious reaction and side effect(s): Intestinal Perforation, Rectal Haemorrhage after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Clexane treatment in female patients, resulting in Intestinal Perforation side effect. The patient was hospitalized.
Clexane Side Effect Report#9775380
Hypovolaemic Shock, Cardiac Arrest, Retroperitoneal Haematoma
This report suggests a potential Clexane Hypovolaemic Shock side effect(s) that can have serious consequences. A 75-year-old male patient (weight: NA) from ES was diagnosed with the following symptoms/conditions: ventricular tachycardia and used Clexane (dosage: 70mg) starting
Mar 15, 2013. After starting Clexane the patient began experiencing various side effects, including: Hypovolaemic Shock, Cardiac Arrest, Retroperitoneal HaematomaAdditional drugs used concurrently:
  • Acetylsalicylic Acid (1cp)
  • Clopidogrel Bisulfate (1cp)
  • Allopurinol (1cp)
  • Carvedilol (1-0-1)
  • Ceftriaxone (2gr)
  • Enalapril (1-0-0)
  • Insulin Glargine (12u De)
  • Pantoprazole (1cp)
The patient was hospitalized. Although Clexane demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Hypovolaemic Shock, may still occur.
Clexane Side Effect Report#9769596
Abortion, Exposure During Pregnancy
This Abortion problem was reported by a consumer or non-health professional from BR. A 36-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Clexane (dosage: NA). The following drugs were being taken at the same time: NA. When using Clexane, the patient experienced the following unwanted symptoms/side effects: Abortion, Exposure During PregnancyAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Abortion, may become evident only after a product is in use by the general population.
Clexane Side Effect Report#9732720
Pulmonary Embolism, Loss Of Consciousness, Cyanosis, Dyspnoea
This Pulmonary Embolism side effect was reported by a health professional from UA. A 52-year-old female patient (weight:NA) experienced the following symptoms/conditions: thrombosis prophylaxis.The patient was prescribed Clexane (drug dosage: NA), which was initiated on
Oct 28, 2013. Concurrently used drugs: NA..After starting to take Clexane the consumer reported adverse symptoms, such as: Pulmonary Embolism, Loss Of Consciousness, Cyanosis, DyspnoeaThese side effects may potentially be related to Clexane.
Clexane Side Effect Report#9725692
Amniotic Fluid Volume Decreased, Exposure During Pregnancy
This is a report of a 31-year-old female patient (weight: NA) from BR, suffering from the following health symptoms/conditions: antiphospholipid syndrome,nutritional supplementation, who was treated with Clexane (dosage: Form: Syringe,route: Injection?strength : 40 Mg Dose:1 Unit(s), start time:
Dec 11, 2012), combined with:
  • Folic Acid (After Lunch)
  • Acetylsalicylic Acid (After Lunch)
and developed a serious reaction and side effect(s): Amniotic Fluid Volume Decreased, Exposure During Pregnancy after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Clexane treatment in female patients, resulting in Amniotic Fluid Volume Decreased side effect.
Clexane Side Effect Report#9716687
Malignant Palate Neoplasm, Benign Muscle Neoplasm, Erythema, Exposure During Pregnancy
This report suggests a potential Clexane Malignant Palate Neoplasm side effect(s) that can have serious consequences. A 37-year-old female patient (weight: NA) from BR was diagnosed with the following symptoms/conditions: thrombosis and used Clexane (dosage: NA) starting NS. After starting Clexane the patient began experiencing various side effects, including: Malignant Palate Neoplasm, Benign Muscle Neoplasm, Erythema, Exposure During PregnancyAdditional drugs used concurrently: NA. Although Clexane demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Malignant Palate Neoplasm, may still occur.
Clexane Side Effect Report#9707877
Abortion Spontaneous, Exposure During Pregnancy
This Abortion Spontaneous problem was reported by a physician from ZA. A female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Clexane (dosage: NA). The following drugs were being taken at the same time:
  • Ecotrin (Strength: 81 Mg)
When using Clexane, the patient experienced the following unwanted symptoms/side effects: Abortion Spontaneous, Exposure During PregnancyAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Abortion Spontaneous, may become evident only after a product is in use by the general population.
Clexane Side Effect Report#9704861
Panniculitis, Injection Site Infection
This Panniculitis side effect was reported by a physician from ES. A 48-year-old female patient (weight:NA) experienced the following symptoms/conditions: deep vein thrombosis.The patient was prescribed Clexane (drug dosage: NA), which was initiated on
Jan 30, 2013. Concurrently used drugs: NA..After starting to take Clexane the consumer reported adverse symptoms, such as: Panniculitis, Injection Site InfectionThese side effects may potentially be related to Clexane.
Clexane Side Effect Report#9704850
Foetal Heart Rate Abnormal, Exposure During Pregnancy, Abortion
This is a report of a 41-year-old female patient (weight: NA) from BR, suffering from the following health symptoms/conditions: thrombosis, who was treated with Clexane (dosage: NA, start time: 201211), combined with:
  • Folic Acid
and developed a serious reaction and side effect(s): Foetal Heart Rate Abnormal, Exposure During Pregnancy, Abortion after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Clexane treatment in female patients, resulting in Foetal Heart Rate Abnormal side effect.
Clexane Side Effect Report#9698207
Pulmonary Embolism, Cardiopulmonary Failure
This report suggests a potential Clexane Pulmonary Embolism side effect(s) that can have serious consequences. A 62-year-old female patient (weight: NA) from UA was diagnosed with the following symptoms/conditions: thrombosis prophylaxis and used Clexane (dosage: NA) starting
Oct 22, 2013. After starting Clexane the patient began experiencing various side effects, including: Pulmonary Embolism, Cardiopulmonary FailureAdditional drugs used concurrently: NA. Although Clexane demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Pulmonary Embolism, may still occur.
Clexane Side Effect Report#9690399
Anaemia, Electrolyte Imbalance
This Anaemia problem was reported by a pharmacist from IT. A 87-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: hip fracture. On
Aug 10, 2013 this consumer started treatment with Clexane T (dosage: NA). The following drugs were being taken at the same time:
  • Metformin Hydrochloride (Strength: 850 Mg)
When using Clexane T, the patient experienced the following unwanted symptoms/side effects: Anaemia, Electrolyte ImbalanceThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Anaemia, may become evident only after a product is in use by the general population.
Clexane Side Effect Report#9685412
Blood Calcium Decreased, Foetal Exposure During Pregnancy
This Blood Calcium Decreased side effect was reported by a health professional from BR. A male patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Clexane (drug dosage: NA), which was initiated on
Jan 10, 2013. Concurrently used drugs:
  • Aas
  • Heparin
  • Enoxaparin Sodium
.After starting to take Clexane the consumer reported adverse symptoms, such as: Blood Calcium Decreased, Foetal Exposure During PregnancyThese side effects may potentially be related to Clexane.
Clexane Side Effect Report#9677817
Hepatitis
This is a report of a 65-year-old male patient (weight: NA) from ES, suffering from the following health symptoms/conditions: thrombosis prophylaxis,pain,meningitis meningococcal, who was treated with Clexane (dosage: 40mg, start time:
Feb 01, 2013), combined with:
  • Paracetamol (1-1-1)
  • Ampicilina (2gr/4h)
  • Meropenem (2gr/8h)
  • Dexamethasone (4mg/6h X 5 Days Followed 4mg/12h X 3 Days)
and developed a serious reaction and side effect(s): Hepatitis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Clexane treatment in male patients, resulting in Hepatitis side effect.


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The appearance of Clexane on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

What are common Clexane Side Effects for Women?

Women Side Effects Reports
Exposure During Pregnancy 57
Pulmonary Embolism 32
Alanine Aminotransferase Increased 31
Aspartate Aminotransferase Increased 28
Anaemia 26
Hepatic Function Abnormal 26
Abortion Spontaneous 20
Haematoma 18
Hypotension 18
Gamma-glutamyltransferase Increased 14

What are common Clexane Side Effects for Men?

Men Side Effects Reports
Pulmonary Embolism 28
Alanine Aminotransferase Increased 20
Liver Injury 19
Thrombocytopenia 19
Aspartate Aminotransferase Increased 18
Anaemia 15
Death 10
Hepatitis 9
Jaundice 9
Myocardial Infarction 9

Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Clexane reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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