CLOFARABINE Side Effects

7017615-7 | Cytolytic Hepatitis
on Sep 21, 2010 Male patient from FRANCE , 45 years of age, weighting 154.3 lb, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine (View Usage). Patient experienced the following unwanted or unexpected effects: cytolytic hepatitis. Clofarabine dosage: 30 Mg/m2, Qdx5. During the same period patient was treated with CYTARABINE (1 G/day, Qd) (View Cytarabine Review and Cytarabine Label ), NEUPOGEN (5 Mcg/kg, Qd) (View Neupogen Review and Neupogen Label ), IMOVANE (1 Other, Qd) (View Imovane Review and Imovane Label ), LEVOFLOXACIN (1 Other, Qd) (View Levofloxacin Review and Levofloxacin Label ).

7012902-0 | Leukoencephalopathy, Lipase Increased
Patient was taking Clofarabine (View Usage). Patient had the following side effects: leukoencephalopathy, lipase increased on Sep 20, 2010 from UNITED STATES Additional patient health information: Female patient , weighting 98.99 lb, was diagnosed with acute lymphocytic leukaemia, prophylaxis and. Clofarabine dosage: 57 Mg, Qd. During the same period patient was treated with ETOPOSIDE (144 Mg, Qd) (View Etoposide Review and Etoposide Label ), CYCLOPHOSPHAMIDE (630 Mg, Qd) (View Cyclophosphamide Review and Cyclophosphamide Label ), VINCRISTINE (2 Mg, Qd) (View Vincristine Review and Vincristine Label ), METHOTREXATE (15 Mg, Qd) (View Methotrexate Review and Methotrexate Label ), ALLOPURINOL (Unk) (View Allopurinol Review and Allopurinol Label ), ACYCLOVIR (800 Mg, Unk) (View Acyclovir Review and Acyclovir Label ). Patient was hospitalized.

6987199-8 | Non-hodgkin's Lymphoma
Adverse event was reported on Sep 07, 2010 by a Male patient taking Clofarabine (View Usage) (Dosage: 40 Mg/m2, Qdx5) was diagnosed with non-hodgkin's lymphoma and. Location: ARGENTINA , 17 years of age, After Clofarabine was administered, patient had the following side effects: non-hodgkin's lymphoma. During the same period patient was treated with CYTARABINE (View Cytarabine Review and Cytarabine Label ).

6972676-6 | Aplasia, Necrotising Fasciitis, Septic Shock
on Aug 27, 2010 Female patient from FRANCE , weighting 103.6 lb, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine (View Usage). Patient experienced the following unwanted or unexpected effects: aplasia, necrotising fasciitis, septic shock. Clofarabine dosage: 43.5 Mg, Qdx5. During the same period patient was treated with CYTARABINE (1450 Mg, Qdx5) (View Cytarabine Review and Cytarabine Label ), IMIPENEM AND CILASTATIN (500 Mg, Bid) (View Imipenem And Cilastatin Review and Imipenem And Cilastatin Label ), AMIKIN (350 Mg, Bid) (View Amikin Review and Amikin Label ), TRIFLUCAN (400 Mg, Qd) (View Triflucan Review and Triflucan Label ), ZOVIRAX (500 Mg, Tid) (View Zovirax Review and Zovirax Label ), VANCOMYCIN (1.5 G, Qd) (View Vancomycin Review and Vancomycin Label ), NEUPOGEN (1 Other, Qd) (View Neupogen Review and Neupogen Label ), ACUPAN (4 Other, Qd) (View Acupan Review and Acupan Label ). Patient was hospitalized and became disabled.


6970536-8 | Lipase Increased
on Sep 03, 2010 Female patient from UNITED STATES , weighting 159.4 lb, was diagnosed with leukaemia, antifungal prophylaxis, oral disorder and was treated with Clofarabine (View Usage). Patient had the following side effects: lipase increased. Clofarabine dosage: 52 Mg/m2, Qdx5. During the same period patient was treated with CYTARABINE (1000 Mg/m2, Qdx5) (View Cytarabine Review and Cytarabine Label ), LEVAQUIN (View Levaquin Review and Levaquin Label ), PENTAMIDINE ISETHIONATE (300 Mg, Q4w) (View Pentamidine Isethionate Review and Pentamidine Isethionate Label ), FLUCONAZOLE (200 Mg, Qd) (View Fluconazole Review and Fluconazole Label ), VALACYCLOVIR (1000 Mg, Tid) (View Valacyclovir Review and Valacyclovir Label ).

6970520-4 | Leukoencephalopathy, Lipase Increased
Patient was taking Clofarabine (View Usage). After Clofarabine was administered, patient had the following side effects: leukoencephalopathy, lipase increased on Aug 26, 2010 from UNITED STATES Additional patient health information: Female patient , weighting 98.99 lb, was diagnosed with acute lymphocytic leukaemia, prophylaxis and. Clofarabine dosage: 57 Mg, Qd. During the same period patient was treated with ETOPOSIDE (144 Mg, Qd) (View Etoposide Review and Etoposide Label ), CYCLOPHOSPHAMIDE (630 Mg, Qd) (View Cyclophosphamide Review and Cyclophosphamide Label ), VINCRISTINE (2 Mg, Qd) (View Vincristine Review and Vincristine Label ), METHOTREXATE (15 Mg, Qd) (View Methotrexate Review and Methotrexate Label ), ALLOPURINOL (Unk) (View Allopurinol Review and Allopurinol Label ), ACYCLOVIR (800 Mg, Unk) (View Acyclovir Review and Acyclovir Label ). Patient was hospitalized.

6968902-X | Disease Progression, Pneumonia, Respiratory Failure
Adverse event was reported on Aug 30, 2010 by a Male patient taking Clofarabine (View Usage) (Dosage: 10 Mg, Qdx5 Days 1-5) was diagnosed with acute myeloid leukaemia and. Location: UNITED STATES , weighting 218.5 lb, Patient experienced the following unwanted or unexpected effects: disease progression, pneumonia (What is pneumonia?), respiratory failure. During the same period patient was treated with ARA C (20 Mg, Bid) (View Ara-c Review and Ara-c Label ), AMICAR (View Amicar Review and Amicar Label ), LEVAQUIN (View Levaquin Review and Levaquin Label ), FLUCONAZOLE (View Fluconazole Review and Fluconazole Label ), LASIX (View Lasix Review and Lasix Label ). Patient was hospitalized.

6965582-4 | Atrial Fibrillation, Escherichia Bacteraemia, Hypotension, Pulmonary Vascular Resistance Abnormality, Renal Failure Acute, Respiratory Failure, Sepsis
on Aug 25, 2010 Male patient from UNITED STATES , weighting 163.1 lb, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine (View Usage). Patient had the following side effects: atrial fibrillation (What is atrial fibrillation?), escherichia bacteraemia, hypotension, pulmonary vascular resistance abnormality, renal failure acute, respiratory failure, sepsis (What is sepsis?). Clofarabine dosage: . During the same period patient was treated with ARA C (View Ara-c Review and Ara-c Label ). Patient was hospitalized.

6945843-5 | Pneumonia
on Aug 18, 2010 Male patient from FRANCE , weighting 216.1 lb, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine (View Usage). After Clofarabine was administered, patient had the following side effects: pneumonia (What is pneumonia?). Clofarabine dosage: . During the same period patient was treated with ARA C (1 G/m2, Qdx5) (View Ara-c Review and Ara-c Label ), IMIPENEM AND CILASTATIN (1 G, Tid) (View Imipenem And Cilastatin Review and Imipenem And Cilastatin Label ), CIFLOX (400 Mg, Bid) (View Ciflox Review and Ciflox Label ), VANCOMYCIN (1 G, Bid) (View Vancomycin Review and Vancomycin Label ), NOXAFIL (200 Mg, Tid) (View Noxafil Review and Noxafil Label ), ZELITREX (500 Mg, Bid) (View Zelitrex Review and Zelitrex Label ), OMEPRAZOLE (View Omeprazole Review and Omeprazole Label ).

6934132-0 | Lipase Increased
Patient was taking Clofarabine (View Usage). Patient experienced the following unwanted or unexpected effects: lipase increased on Aug 09, 2010 from UNITED STATES Additional patient health information: Female patient , weighting 98.99 lb, was diagnosed with acute lymphocytic leukaemia, prophylaxis and. Clofarabine dosage: 57 Mg, Qd. During the same period patient was treated with ETOPOSIDE (144 Mg, Qd) (View Etoposide Review and Etoposide Label ), CYCLOPHOSPHAMIDE (630 Mg, Qd) (View Cyclophosphamide Review and Cyclophosphamide Label ), VINCRISTINE (2 Mg, Qd) (View Vincristine Review and Vincristine Label ), METHOTREXATE (15 Mg, Qd) (View Methotrexate Review and Methotrexate Label ), ALLOPURINOL (Unk) (View Allopurinol Review and Allopurinol Label ), ACYCLOVIR (800 Mg, Unk) (View Acyclovir Review and Acyclovir Label ), CALCIUM CARBONATE (500 Mg, Unk) (View Calcium Carbonate Review and Calcium Carbonate Label ).

6924006-3 | Bone Marrow Failure, Cardiac Failure Congestive, Enterococcal Bacteraemia, Fungal Infection, Fungal Skin Infection, Pneumonia Fungal
Adverse event was reported on Aug 02, 2010 by a Female patient taking Clofarabine (View Usage) (Dosage: 32 Mg, Qd) was diagnosed with acute lymphocytic leukaemia, prophylaxis, infection (What is infection?) and. Location: UNITED STATES , weighting 57.32 lb, Patient had the following side effects: bone marrow failure, cardiac failure congestive, enterococcal bacteraemia, fungal infection (What is fungal infection?), fungal skin infection, pneumonia fungal. During the same period patient was treated with ETOPOSIDE (80 Mg, Qd) (View Etoposide Review and Etoposide Label ), CYCLOPHOSPHAMIDE (350 Mg, Qd) (View Cyclophosphamide Review and Cyclophosphamide Label ), ACYCLOVIR (800 Mg, Unk) (View Acyclovir Review and Acyclovir Label ). Patient was hospitalized.

6920099-8 | Caecitis, Clostridial Infection, Enterococcal Bacteraemia, Escherichia Infection, Febrile Neutropenia, Pneumonia
on Aug 05, 2010 Male patient from UNITED STATES , weighting 165.3 lb, was diagnosed with acute lymphocytic leukaemia, white blood cell count decreased, pain (What is pain?), chills, pyrexia, herpes virus infection, epistaxis and was treated with Clofarabine (View Usage). After Clofarabine was administered, patient had the following side effects: caecitis, clostridial infection, enterococcal bacteraemia, escherichia infection, febrile neutropenia, pneumonia (What is pneumonia?). Clofarabine dosage: 77 Mg, Qd. During the same period patient was treated with ETOPOSIDE (193 Mg, Qd) (View Etoposide Review and Etoposide Label ), CYCLOPHOSPHAMIDE (850 Mg, Qd) (View Cyclophosphamide Review and Cyclophosphamide Label ), GRANULOCYTE COLONY STIMULATING FACTOR (300 Mcg, Unk) (View Granulocyte Colony Stimulating Factor Review and Granulocyte Colony Stimulating Factor Label ), ACETAMINOPHEN (650 Mg, Unk) (View Acetaminophen Review and Acetaminophen Label ), ACYCLOVIR (400 Mg, Unk) (View Acyclovir Review and Acyclovir Label ), AMICAR (6 G, Unk) (View Amicar Review and Amicar Label ). Patient was hospitalized.

6915141-4 | Capillary Leak Syndrome, Central Nervous System Infection, Herpes Zoster, Hyperuricaemia, Hypokalaemia, Hypophosphataemia, Hypotension, Leukocytosis, Lung Infection
on Jul 27, 2010 Male patient from UNITED STATES , weighting 197.5 lb, was diagnosed with acute lymphocytic leukaemia, pyrexia, hypertension and was treated with Clofarabine (View Usage). Patient experienced the following unwanted or unexpected effects: capillary leak syndrome, central nervous system infection, herpes zoster, hyperuricaemia, hypokalaemia, hypophosphataemia, hypotension, leukocytosis, lung infection. Clofarabine dosage: 88 Mg, Qd. During the same period patient was treated with ETOPOSIDE (220 Mg, Qd) (View Etoposide Review and Etoposide Label ), CYCLOPHOSPHAMIDE (968 Mg, Qd) (View Cyclophosphamide Review and Cyclophosphamide Label ), VANCOMYCIN (900 Mg, Once) (View Vancomycin Review and Vancomycin Label ), CLINDAMYCIN (900 Mg, Unk) (View Clindamycin Review and Clindamycin Label ), LISINOPRIL (5 Mg, Unk) (View Lisinopril Review and Lisinopril Label ). Patient was hospitalized.

6914771-3 | Lipase Increased
Patient was taking Clofarabine (View Usage). Patient had the following side effects: lipase increased on Jul 29, 2010 from UNITED STATES Additional patient health information: Female patient , weighting 159.4 lb, was diagnosed with leukaemia, antifungal prophylaxis, oral disorder and. Clofarabine dosage: 52 Mg/m2, Qdx5. During the same period patient was treated with CYTARABINE (1000 Mg/m2, Qdx5) (View Cytarabine Review and Cytarabine Label ), LEVAQUIN (View Levaquin Review and Levaquin Label ), PENTAMIDINE ISETHIONATE (300 Mg, Q4w) (View Pentamidine Isethionate Review and Pentamidine Isethionate Label ), FLUCONAZOLE (200 Mg, Qd) (View Fluconazole Review and Fluconazole Label ), VALACYCLOVIR (1000 Mg, Tid) (View Valacyclovir Review and Valacyclovir Label ).

6901782-7 | Caecitis, Clostridial Infection, Enterococcal Bacteraemia, Escherichia Infection, Febrile Neutropenia, Pneumonia
Adverse event was reported on Jul 26, 2010 by a Male patient taking Clofarabine (View Usage) (Dosage: 77 Mg, Qd) was diagnosed with acute lymphocytic leukaemia, white blood cell count decreased, pain (What is pain?), chills, pyrexia, herpes virus infection, epistaxis and. Location: UNITED STATES , weighting 165.3 lb, After Clofarabine was administered, patient had the following side effects: caecitis, clostridial infection, enterococcal bacteraemia, escherichia infection, febrile neutropenia, pneumonia (What is pneumonia?). During the same period patient was treated with ETOPOSIDE (193 Mg, Qd) (View Etoposide Review and Etoposide Label ), CYCLOPHOSPHAMIDE (850 Mg, Qd) (View Cyclophosphamide Review and Cyclophosphamide Label ), GRANULOCYTE COLONY STIMULATING FACTOR (300 Mcg, Unk) (View Granulocyte Colony Stimulating Factor Review and Granulocyte Colony Stimulating Factor Label ), ACETAMINOPHEN (650 Mg, Unk) (View Acetaminophen Review and Acetaminophen Label ), ACYCLOVIR (400 Mg, Unk) (View Acyclovir Review and Acyclovir Label ), AMICAR (6 G, Unk) (View Amicar Review and Amicar Label ). Patient was hospitalized.

6888359-7 | Alpha Haemolytic Streptococcal Infection, Klebsiella Infection, Pancytopenia, Septic Shock
on Jul 20, 2010 Male patient from UNITED STATES , weighting 240.3 lb, was diagnosed with acute lymphocytic leukaemia, white blood cell count increased, nausea (What is nausea?) and was treated with Clofarabine (View Usage). Patient experienced the following unwanted or unexpected effects: alpha haemolytic streptococcal infection, klebsiella infection, pancytopenia, septic shock. Clofarabine dosage: 40 Mg/m2, Qdx 4 Days. During the same period patient was treated with ETOPOSIDE (100 Mg/m2, Qd X 4days) (View Etoposide Review and Etoposide Label ), CYCLOPHOSPHAMIDE (440 Mg/m2, Qd) (View Cyclophosphamide Review and Cyclophosphamide Label ), NEUPOGEN (300 Mcg, Unk) (View Neupogen Review and Neupogen Label ), ONDANSETRON (10 Mg, Unk) (View Ondansetron Review and Ondansetron Label ). Patient was hospitalized.

6880563-7 | Aplasia, Necrotising Fasciitis, Septic Shock
on Jul 16, 2010 Female patient from FRANCE , weighting 103.6 lb, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine (View Usage). Patient had the following side effects: aplasia, necrotising fasciitis, septic shock. Clofarabine dosage: 43.5 Mg, Qdx5. During the same period patient was treated with CYTARABINE (1450 Mg, Qdx5) (View Cytarabine Review and Cytarabine Label ), IMIPENEM AND CILASTATIN (500 Mg, Bid) (View Imipenem And Cilastatin Review and Imipenem And Cilastatin Label ), AMIKIN (350 Mg, Bid) (View Amikin Review and Amikin Label ), FLUCONAZOLE (400 Mg, Qd) (View Fluconazole Review and Fluconazole Label ), ZOVIRAX (500 Mg, Tid) (View Zovirax Review and Zovirax Label ), VANCOMYCIN (1.5 G, Qd) (View Vancomycin Review and Vancomycin Label ), NEUPOGEN (1 Other, Qd) (View Neupogen Review and Neupogen Label ), ACUPAN (4 Other, Qd) (View Acupan Review and Acupan Label ). Patient was hospitalized.

6863033-1 | Haemoglobin Decreased, Haemorrhage Urinary Tract, Platelet Count Decreased
Patient was taking Clofarabine (View Usage). After Clofarabine was administered, patient had the following side effects: haemoglobin decreased, haemorrhage urinary tract, platelet count decreased on Jul 12, 2010 from UNITED STATES Additional patient health information: Male patient , 66 years of age, was diagnosed with acute leukaemia, prophylaxis of nausea and vomiting and. Clofarabine dosage: 25 Mg, Unk. During the same period patient was treated with CALCIUM ACETATE (667 Mg, Bid) (View Calcium Acetate Review and Calcium Acetate Label ), ALLOPURINOL (300 Mg, Qd) (View Allopurinol Review and Allopurinol Label ), COMPAZINE (10 Mg/day, Prn) (View Compazine Review and Compazine Label ). Patient was hospitalized.

6862240-1 | Capillary Leak Syndrome, Central Nervous System Infection, Herpes Zoster, Hyperuricaemia, Hypokalaemia, Hypophosphataemia, Hypotension, Leukocytosis, Lung Infection
Adverse event was reported on Jul 09, 2010 by a Male patient taking Clofarabine (View Usage) (Dosage: 88 Mg, Qd) was diagnosed with acute lymphocytic leukaemia, pyrexia, hypertension and. Location: UNITED STATES , weighting 197.5 lb, Patient experienced the following unwanted or unexpected effects: capillary leak syndrome, central nervous system infection, herpes zoster, hyperuricaemia, hypokalaemia, hypophosphataemia, hypotension, leukocytosis, lung infection. During the same period patient was treated with ETOPOSIDE (220 Mg, Qd) (View Etoposide Review and Etoposide Label ), CYCLOPHOSPHAMIDE (968 Mg, Qd) (View Cyclophosphamide Review and Cyclophosphamide Label ), VANCOMYCIN (900 Mg, Once) (View Vancomycin Review and Vancomycin Label ), CLINDAMYCIN (900 Mg, Unk) (View Clindamycin Review and Clindamycin Label ), LISINOPRIL (5 Mg, Unk) (View Lisinopril Review and Lisinopril Label ). Patient was hospitalized.

6856749-4 | Lipase Increased
on Jul 07, 2010 Female patient from UNITED STATES , 20 years of age, weighting 155.4 lb, was diagnosed with leukaemia and was treated with Clofarabine (View Usage). Patient had the following side effects: lipase increased. Clofarabine dosage: 52 Mg/m2, Qdx5. During the same period patient was treated with CYTARABINE (1000 Mg/m2, Qdx5) (View Cytarabine Review and Cytarabine Label ), LEVAQUIN (View Levaquin Review and Levaquin Label ), PENTAMIDINE ISETHIONATE (View Pentamidine Isethionate Review and Pentamidine Isethionate Label ).

6839607-0 | Bone Marrow Failure, Cardiac Failure Congestive, Enterococcal Bacteraemia, Fungal Infection, Fungal Skin Infection, Pneumonia Fungal
on Jul 01, 2010 Female patient from UNITED STATES , weighting 57.32 lb, was diagnosed with acute lymphocytic leukaemia, prophylaxis, infection (What is infection?) and was treated with Clofarabine (View Usage). After Clofarabine was administered, patient had the following side effects: bone marrow failure, cardiac failure congestive, enterococcal bacteraemia, fungal infection (What is fungal infection?), fungal skin infection, pneumonia fungal. Clofarabine dosage: 32 Mg, Qd. During the same period patient was treated with ETOPOSIDE (80 Mg, Qd) (View Etoposide Review and Etoposide Label ), CYCLOPHOSPHAMIDE (350 Mg, Qd) (View Cyclophosphamide Review and Cyclophosphamide Label ), ACYCLOVIR (800 Mg, Unk) (View Acyclovir Review and Acyclovir Label ). Patient was hospitalized.

6831612-3 | Alpha Haemolytic Streptococcal Infection, Febrile Neutropenia, Hypotension, Klebsiella Infection, Pancytopenia, Septic Shock
Patient was taking Clofarabine (View Usage). Patient experienced the following unwanted or unexpected effects: alpha haemolytic streptococcal infection, febrile neutropenia, hypotension, klebsiella infection, pancytopenia, septic shock on Jun 29, 2010 from UNITED STATES Additional patient health information: Male patient , weighting 240.3 lb, was diagnosed with acute lymphocytic leukaemia, white blood cell count increased, pain (What is pain?) and. Clofarabine dosage: 40 Mg/m2, Qdx 4 Days. During the same period patient was treated with ETOPOSIDE (100 Mg/m2, Qd X 4days) (View Etoposide Review and Etoposide Label ), CYCLOPHOSPHAMIDE (440 Mg/m2, Qd) (View Cyclophosphamide Review and Cyclophosphamide Label ), NEUPOGEN (300 Mcg, Unk) (View Neupogen Review and Neupogen Label ), MORPHINE (5.5 Mg, Unk) (View Morphine Review and Morphine Label ). Patient was hospitalized.

6821790-4 | Bone Marrow Failure, Cardiac Failure Congestive, Enterococcal Bacteraemia, Fungal Infection, Fungal Skin Infection, Pneumonia Fungal
Adverse event was reported on Jul 01, 2010 by a Female patient taking Clofarabine (View Usage) (Dosage: 32 Mg, Qd) was diagnosed with acute lymphocytic leukaemia, prophylaxis, infection (What is infection?) and. Location: UNITED STATES , weighting 57.32 lb, Patient had the following side effects: bone marrow failure, cardiac failure congestive, enterococcal bacteraemia, fungal infection (What is fungal infection?), fungal skin infection, pneumonia fungal. During the same period patient was treated with ETOPOSIDE (80 Mg, Qd) (View Etoposide Review and Etoposide Label ), CYCLOPHOSPHAMIDE (350 Mg, Qd) (View Cyclophosphamide Review and Cyclophosphamide Label ), ACYCLOVIR (800 Mg, Unk) (View Acyclovir Review and Acyclovir Label ). Patient was hospitalized.

6817100-9 | Acute Myeloid Leukaemia, Renal Failure Acute, Sepsis
on Jun 23, 2010 Male patient from UNITED STATES , weighting 177.9 lb, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine (View Usage). After Clofarabine was administered, patient had the following side effects: acute myeloid leukaemia, renal failure acute, sepsis (What is sepsis?). Clofarabine dosage: Unk. During the same period patient was treated with CYTARABINE (Unk) (View Cytarabine Review and Cytarabine Label ).

6815318-2 | Bradycardia, Cardio-respiratory Arrest, Hyperdynamic Left Ventricle, No Therapeutic Response, Respiratory Distress, Septic Shock
on Jul 01, 2010 Female patient from UNITED STATES , weighting 185.4 lb, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine (View Usage). Patient experienced the following unwanted or unexpected effects: bradycardia, cardio-respiratory arrest, hyperdynamic left ventricle, no therapeutic response, respiratory distress, septic shock. Clofarabine dosage: 60 Mg Daily Iv Drip.

6815216-4 | Bacterial Test Positive, Caecitis, Clostridium Test Positive, Escherichia Infection, Febrile Neutropenia, Pneumonia
Patient was taking Clofarabine (View Usage). Patient had the following side effects: bacterial test positive, caecitis, clostridium test positive, escherichia infection, febrile neutropenia, pneumonia (What is pneumonia?) on Jun 22, 2010 from UNITED STATES Additional patient health information: Male patient , weighting 165.3 lb, was diagnosed with acute lymphocytic leukaemia, white blood cell count decreased, pain (What is pain?), chills, pyrexia, herpes virus infection, epistaxis and. Clofarabine dosage: 77 Mg, Qd. During the same period patient was treated with ETOPOSIDE (193 Mg, Qd) (View Etoposide Review and Etoposide Label ), CYCLOPHOSPHAMIDE (850 Mg, Qd) (View Cyclophosphamide Review and Cyclophosphamide Label ), GRANULOCYTE COLONY STIMULATING FACTOR (300 Mcg, Unk) (View Granulocyte Colony Stimulating Factor Review and Granulocyte Colony Stimulating Factor Label ), ACETAMINOPHEN (650 Mg, Unk) (View Acetaminophen Review and Acetaminophen Label ), ACYCLOVIR (400 Mg, Unk) (View Acyclovir Review and Acyclovir Label ), AMICAR (6 G, Unk) (View Amicar Review and Amicar Label ). Patient was hospitalized.

6803749-6 | Fungal Infection
Adverse event was reported on Jun 16, 2010 by a Male patient taking Clofarabine (View Usage) (Dosage: 35 Mg, Qdx5) was diagnosed with myelodysplastic syndrome and. Location: UNITED STATES , weighting 179.9 lb, After Clofarabine was administered, patient had the following side effects: fungal infection (What is fungal infection?). Patient was hospitalized.

6795709-9 | Fluid Overload, Hyperbilirubinaemia, Hypoxia
on Jun 15, 2010 Male patient from UNITED STATES , 64 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Clofarabine (View Usage). Patient experienced the following unwanted or unexpected effects: fluid overload, hyperbilirubinaemia, hypoxia. Clofarabine dosage: 40 Mg/m2, Qd. During the same period patient was treated with NIFEDIPINE (Unk Unk, Unk) (View Nifedipine Review and Nifedipine Label ), METOPROLOL (Unk Unk, Unk) (View Metoprolol Review and Metoprolol Label ), CYCLOSPORINE (Unk Unk, Unk) (View Cyclosporine Review and Cyclosporine Label ), METHYLPREDNISOLONE (Unk Unk, Unk) (View Methylprednisolone Review and Methylprednisolone Label ), MEROPENEM (Unk Unk, Unk) (View Meropenem Review and Meropenem Label ), VANCOMYCIN (Unk Unk, Unk) (View Vancomycin Review and Vancomycin Label ), ACYCLOVIR (Unk Unk, Unk) (View Acyclovir Review and Acyclovir Label ), URSODIOL (Unk Unk, Unk) (View Ursodiol Review and Ursodiol Label ). Patient was hospitalized.

6794797-3 | Disorientation, Mental Status Changes, Partial Seizures, Syncope, Transient Ischaemic Attack
on Jun 24, 2010 Female patient from UNITED STATES , weighting 185.4 lb, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine (View Usage). Patient had the following side effects: disorientation, mental status changes, partial seizures, syncope, transient ischaemic attack. Clofarabine dosage: 60 Mg Daily Iv Drip.

6785870-4 | Lung Neoplasm, Pneumonia Fungal, Sinusitis Aspergillus
Patient was taking Clofarabine (View Usage). After Clofarabine was administered, patient had the following side effects: lung neoplasm, pneumonia fungal, sinusitis aspergillus on Jun 21, 2010 from UNITED STATES Additional patient health information: Male patient , weighting 257.9 lb, was diagnosed with chronic myeloid leukaemia, myelodysplastic syndrome and. Clofarabine dosage: 74 Mg Daily Iv Drip. Patient was hospitalized.

6784843-5 | Neutropenic Sepsis
Adverse event was reported on Mar 14, 2008 by a Female patient taking Clofarabine (View Usage) (Dosage: 40 Mg/m2, Qdx5) was diagnosed with acute leukaemia and. Location: UNITED KINGDOM , weighting 141.1 lb, Patient experienced the following unwanted or unexpected effects: neutropenic sepsis. During the same period patient was treated with CYTARABINE (1 G/m2, Qdx5) (View Cytarabine Review and Cytarabine Label ), HYDROXYUREA (1 Bpm, Bid) (View Hydroxyurea Review and Hydroxyurea Label ), ACYCLOVIR (200 Mg, Tid) (View Acyclovir Review and Acyclovir Label ), ALLOPURINOL (300 Mg, Q12hr) (View Allopurinol Review and Allopurinol Label ), FLUCONAZOLE (200 Mg, Qd) (View Fluconazole Review and Fluconazole Label ), LEVOTHYROXINE SODIUM (75 Mcg, Qd) (View Levothyroxine Sodium Review and Levothyroxine Sodium Label ), CORSODYL (10 Ml, Qd) (View Corsodyl Review and Corsodyl Label ), ONDANSETRON (8 Mg, Bid) (View Ondansetron Review and Ondansetron Label ).

6784263-3 | Fungal Infection
on Jun 16, 2010 Male patient from UNITED STATES , 79 years of age, was diagnosed with myelodysplastic syndrome and was treated with Clofarabine (View Usage). Patient had the following side effects: fungal infection (What is fungal infection?). Clofarabine dosage: 35 Mg, Qdx5. Patient was hospitalized.

6784109-3 | Acute Myeloid Leukaemia Recurrent, Cough, Haematocrit Decreased, Haemoglobin Decreased, Lung Disorder, Lung Neoplasm, Pyrexia, Red Blood Cell Count Decreased, Thrombocytopenia
on Jun 14, 2010 Male patient from FRANCE , weighting 216.1 lb, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine (View Usage). After Clofarabine was administered, patient had the following side effects: acute myeloid leukaemia recurrent, cough, haematocrit decreased, haemoglobin decreased, lung disorder, lung neoplasm, pyrexia, red blood cell count decreased, thrombocytopenia. Clofarabine dosage: . During the same period patient was treated with ARA C (1 G/m2, Qdx5) (View Ara-c Review and Ara-c Label ), IMIPENEM AND CILASTATIN (1 G, Tid) (View Imipenem And Cilastatin Review and Imipenem And Cilastatin Label ), CIFLOX (400 Mg, Bid) (View Ciflox Review and Ciflox Label ), VANCOMYCIN (1 G, Bid) (View Vancomycin Review and Vancomycin Label ), NOXAFIL (200 Mg, Tid) (View Noxafil Review and Noxafil Label ), ZELITREX (500 Mg, Bid) (View Zelitrex Review and Zelitrex Label ), OMEPRAZOLE (View Omeprazole Review and Omeprazole Label ).

6745830-6 | Toxic Epidermal Necrolysis
Patient was taking Clofarabine (View Usage). Patient experienced the following unwanted or unexpected effects: toxic epidermal necrolysis on May 19, 2010 from FRANCE Additional patient health information: Female patient , weighting 125.7 lb, was diagnosed with acute myeloid leukaemia, nausea (What is nausea?), prophylaxis, toxic epidermal necrolysis and. Clofarabine dosage: . During the same period patient was treated with ARA C (1590 Mg, Qdx5) (View Ara-c Review and Ara-c Label ), APREPITANT (80 Mg, Qd) (View Aprepitant Review and Aprepitant Label ), VALACYCLOVIR (500 Mg, Bid) (View Valacyclovir Review and Valacyclovir Label ), ONDANSETRON (8 Mg, Qd) (View Ondansetron Review and Ondansetron Label ), METHYLPREDNISOLONE (Unk) (View Methylprednisolone Review and Methylprednisolone Label ), LINEZOLID (Unk) (View Linezolid Review and Linezolid Label ).

6727164-9 | Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Bone Marrow Failure, Bronchopulmonary Aspergillosis, Enterococcal Bacteraemia, Febrile Neutropenia, Hyperbilirubinaemia, Pancreatitis, Pulmonary Oedema
Adverse event was reported on May 04, 2010 by a Male patient taking Clofarabine (View Usage) (Dosage: 87 Mg, Qd) was diagnosed with acute lymphocytic leukaemia, prophylaxis, appetite disorder, hypertension, antiemetic supportive care, type 2 diabetes mellitus and. Location: UNITED STATES , weighting 209.4 lb, Patient had the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, bone marrow failure, bronchopulmonary aspergillosis, enterococcal bacteraemia, febrile neutropenia, hyperbilirubinaemia, pancreatitis, pulmonary oedema. During the same period patient was treated with ETOPOSIDE (215 Mg, Qd) (View Etoposide Review and Etoposide Label ), CYCLOPHOSPHAMIDE (950 Mg, Qd) (View Cyclophosphamide Review and Cyclophosphamide Label ), ACYCLOVIR (400 Mg, Unk) (View Acyclovir Review and Acyclovir Label ), CYPROHEPTADINE HCL (4 Mg, Unk) (View Cyproheptadine Hcl Review and Cyproheptadine Hcl Label ), ENALAPRIL MALEATE (5 Mg, Unk) (View Enalapril Maleate Review and Enalapril Maleate Label ), FLUCONAZOLE (200 Mg, Unk) (View Fluconazole Review and Fluconazole Label ), LORAZEPAM (1 Mg, Unk) (View Lorazepam Review and Lorazepam Label ), METFORMIN HYDROCHLORIDE (1000 Mg, Unk) (View Metformin Hydrochloride Review and Metformin Hydrochloride Label ). Patient was hospitalized.

6689201-X | Ear Pain, Febrile Neutropenia, Occult Blood Positive, Rectal Fissure, Vomiting, White Blood Cell Count Decreased
on Apr 01, 2010 Male patient from UNITED STATES , child 5 years of age, weighting 42.33 lb, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine (View Usage). After Clofarabine was administered, patient had the following side effects: ear pain, febrile neutropenia, occult blood positive, rectal fissure, vomiting, white blood cell count decreased. Clofarabine dosage: 15 G, Qdx5, Intravenous. During the same period patient was treated with ETOPOSIDE (76 Mg, Qdx5, Intravenous) (View Etoposide Review and Etoposide Label ), CYCLOPHOSPHAMIDE (335 Mg, Qdx5, Intravenous) (View Cyclophosphamide Review and Cyclophosphamide Label ), NEUPOGEN (View Neupogen Review and Neupogen Label ), BENADRYL (View Benadryl Review and Benadryl Label ), TYLENOL (PARACETAMOL) (View Tylenol (paracetamol) Review and Tylenol (paracetamol) Label ), BACTRIM (View Bactrim Review and Bactrim Label ), KYTRIL (View Kytril Review and Kytril Label ). Patient was hospitalized.

6678618-5 | Activities Of Daily Living Impaired, Erythema, Pain In Extremity
on Apr 12, 2010 Female patient from UNITED STATES , 46 years of age, weighting 188.1 lb, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine (View Usage). Patient experienced the following unwanted or unexpected effects: activities of daily living impaired, erythema, pain in extremity. Clofarabine dosage: 70 Mg Iv Daily X 5 Days. During the same period patient was treated with ALLOPURINOL (View Allopurinol Review and Allopurinol Label ), CLOTRIMAZOLE (View Clotrimazole Review and Clotrimazole Label ), DEXAMETHASONE (View Dexamethasone Review and Dexamethasone Label ). Patient was hospitalized.

6669676-2 | Capillary Leak Syndrome, Herpes Zoster, Hyperuricaemia, Hypokalaemia, Hypophosphataemia, Hypotension, Infection, Leukocytosis, Sepsis
Patient was taking Clofarabine (View Usage). Patient had the following side effects: capillary leak syndrome, herpes zoster, hyperuricaemia, hypokalaemia, hypophosphataemia, hypotension, infection (What is infection?), leukocytosis, sepsis (What is sepsis?) on Mar 26, 2010 from UNITED STATES Additional patient health information: Male patient , weighting 197.5 lb, was diagnosed with acute lymphocytic leukaemia, pyrexia, hypertension and. Clofarabine dosage: 88 Mg, Qd. During the same period patient was treated with ETOPOSIDE (220 Mg, Qd) (View Etoposide Review and Etoposide Label ), CYCLOPHOSPHAMIDE (968 Mg, Qd) (View Cyclophosphamide Review and Cyclophosphamide Label ), VANCOMYCIN (900 Mg, Once) (View Vancomycin Review and Vancomycin Label ), CLINDAMYCIN (900 Mg, Unk) (View Clindamycin Review and Clindamycin Label ), LISINOPRIL (5 Mg, Unk) (View Lisinopril Review and Lisinopril Label ). Patient was hospitalized.

6663836-2 | Febrile Neutropenia, Haemoglobin Decreased, Hypotension, Hypoxia, Streptococcal Bacteraemia, Syncope, Thrombocytopenia
Adverse event was reported on Mar 23, 2010 by a Male patient taking Clofarabine (View Usage) (Dosage: 50 Mg, Qdx5) was diagnosed with acute myeloid leukaemia, neutropenia, prophylaxis and. Location: UNITED STATES , weighting 82.23 lb, After Clofarabine was administered, patient had the following side effects: febrile neutropenia, haemoglobin decreased, hypotension, hypoxia, streptococcal bacteraemia, syncope, thrombocytopenia. During the same period patient was treated with ETOPOSIDE (120 Mg Qdx5) (View Etoposide Review and Etoposide Label ), CYCLOPHOSPHAMIDE (530 Mg, Qdx5) (View Cyclophosphamide Review and Cyclophosphamide Label ), GRANULOCYTE COLONY STIMULATING FACTOR (180 Mcg, Qd) (View Granulocyte Colony Stimulating Factor Review and Granulocyte Colony Stimulating Factor Label ), FLUCONAZOLE (150 Mg, Qd) (View Fluconazole Review and Fluconazole Label ), BACTRIM (400 Unk, Qd) (View Bactrim Review and Bactrim Label ). Patient was hospitalized.

6663753-8 | Gamma-glutamyltransferase Increased
on Mar 22, 2010 Male patient from UNITED STATES , child 7 years of age, weighting 45.42 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Clofarabine (View Usage). Patient experienced the following unwanted or unexpected effects: gamma-glutamyltransferase increased. Clofarabine dosage: 52 Mg/m2, Qdx5. During the same period patient was treated with CYTARABINE (1 G/m2, Qdx5) (View Cytarabine Review and Cytarabine Label ), ATIVAN (View Ativan Review and Ativan Label ), BENADRYL (View Benadryl Review and Benadryl Label ), ZOFRAN (View Zofran Review and Zofran Label ), ALLOPURINOL (View Allopurinol Review and Allopurinol Label ), BACTRIM (View Bactrim Review and Bactrim Label ), BACTROBAN (View Bactroban Review and Bactroban Label ), CEFEPIME (View Cefepime Review and Cefepime Label ).

6613805-3 | Renal Failure, Respiratory Distress
on Feb 22, 2010 Female patient from UNITED STATES , weighting 214.1 lb, was diagnosed with myelodysplastic syndrome and was treated with Clofarabine (View Usage). Patient had the following side effects: renal failure, respiratory distress. Clofarabine dosage: 63 Mg, Qdx5. During the same period patient was treated with MELPHALAN (Unk Unk, Unk) (View Melphalan Review and Melphalan Label ), ALEMTUZUMAB (Unk Unk, Unk) (View Alemtuzumab Review and Alemtuzumab Label ), PEPCID (20 Mg, Bid) (View Pepcid Review and Pepcid Label ), MEPHYTON (10 Mg, 1x/w) (View Mephyton Review and Mephyton Label ), ZOCOR (20 Mg, Qd) (View Zocor Review and Zocor Label ). Patient was hospitalized.

6584545-4 | No Therapeutic Response, Palmar-plantar Erythrodysaesthesia Syndrome
Patient was taking Clofarabine (View Usage). After Clofarabine was administered, patient had the following side effects: no therapeutic response, palmar-plantar erythrodysaesthesia syndrome on Feb 13, 2010 from UNITED STATES Additional patient health information: Female patient , weighting 181.9 lb, was diagnosed with acute myeloid leukaemia and. Clofarabine dosage: 95 9 24? Iv Piggyback. During the same period patient was treated with CYTARABINE (1870mg 9 24? Iv Piggyback) (View Cytarabine Review and Cytarabine Label ), LORAZEPAM (View Lorazepam Review and Lorazepam Label ), NORCO (View Norco Review and Norco Label ), DECADRON (View Decadron Review and Decadron Label ), KYTRIL (View Kytril Review and Kytril Label ), MORPHINE (View Morphine Review and Morphine Label ), PHENERGAN HCL (View Phenergan Hcl Review and Phenergan Hcl Label ).

6522105-1 | Acute Graft Versus Host Disease In Intestine, Acute Graft Versus Host Disease In Liver, Acute Graft Versus Host Disease In Skin, Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Blood Bilirubin Increased, Diarrhoea, Rash
Adverse event was reported on Dec 29, 2009 by a Male patient taking Clofarabine (View Usage) (Dosage: 80 Mg Iv Qd) was diagnosed with acute myeloid leukaemia, leukaemia recurrent and. Location: UNITED STATES , 62 years of age, weighting 176.4 lb, Patient experienced the following unwanted or unexpected effects: acute graft versus host disease in intestine, acute graft versus host disease in liver, acute graft versus host disease in skin, alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, diarrhoea, rash (What is rash?). During the same period patient was treated with ZANTAC (View Zantac Review and Zantac Label ), DOCUSATE (View Docusate Review and Docusate Label ), VARICONAZOLE (View Variconazole Review and Variconazole Label ), METHYLPRED (View Methylpred Review and Methylpred Label ), CEFEPIME (View Cefepime Review and Cefepime Label ).

6277846-0 | Cerebral Toxoplasmosis, Convulsion, Neutropenia, Pyrexia
on Jul 17, 2009 Male patient from UNITED STATES , child 10 years of age, weighting 70.55 lb, was diagnosed with leukaemia recurrent and was treated with Clofarabine (View Usage). Patient had the following side effects: cerebral toxoplasmosis, convulsion, neutropenia, pyrexia. Clofarabine dosage: 58 Mg Once Daily Iv Drip. During the same period patient was treated with ETOPOSIDE (View Etoposide Review and Etoposide Label ), IFOSFAMIDE (View Ifosfamide Review and Ifosfamide Label ). Patient was hospitalized.

6268164-5 | Anaemia, Cellulitis Orbital, Febrile Neutropenia, Platelet Count Abnormal, Staphylococcal Bacteraemia
on Jul 13, 2009 Female patient from UNITED STATES , weighting 141.1 lb, was diagnosed with non-hodgkin's lymphoma and was treated with Clofarabine (View Usage). After Clofarabine was administered, patient had the following side effects: anaemia, cellulitis orbital, febrile neutropenia, platelet count abnormal, staphylococcal bacteraemia. Clofarabine dosage: 6.44 Mg Qd X 5 Days Every 28 Days Iv. Patient was hospitalized.

6260937-8 | Diarrhoea, Eye Swelling, Febrile Neutropenia, Nausea, Sepsis
Patient was taking Clofarabine (View Usage). Patient experienced the following unwanted or unexpected effects: diarrhoea, eye swelling, febrile neutropenia, nausea (What is nausea?), sepsis (What is sepsis?) on Jul 07, 2009 from UNITED STATES Additional patient health information: Female patient , weighting 141.1 lb, was diagnosed with non-hodgkin's lymphoma and. Clofarabine dosage: 6.44 Mg Qd X 5 Days Every 28 Days Iv. Patient was hospitalized.

6182170-0 | Blood Glucose Increased, Treatment Noncompliance
Adverse event was reported on May 05, 2009 by a Male patient taking Clofarabine (View Usage) (Dosage: 4mg/m2 Iv, Days 1-5 Of Each 28 Day Cycle) was diagnosed with disease recurrence, lymphoma (What is lymphoma?) and. Location: UNITED STATES , 59 years of age, weighting 173.0 lb, Patient had the following side effects: blood glucose increased, treatment noncompliance. During the same period patient was treated with MONONITRATE ER (IMDUR) (View Mononitrate Er (imdur) Review and Mononitrate Er (imdur) Label ), SENNA DOCUSATE (SENOKOT S) (View Senna-docusate (senokot-s) Review and Senna-docusate (senokot-s) Label ), MIRALAX (View Miralax Review and Miralax Label ), REGLAN (View Reglan Review and Reglan Label ). Patient was hospitalized.

6181466-6 | Bacteria Blood Identified, Chills
on May 05, 2009 Male patient from UNITED STATES , 70 years of age, weighting 170.0 lb, was diagnosed with lymphoma (What is lymphoma?) and was treated with Clofarabine (View Usage). After Clofarabine was administered, patient had the following side effects: bacteria blood identified, chills. Clofarabine dosage: 4mg/m2. During the same period patient was treated with ACYCLOVIR (View Acyclovir Review and Acyclovir Label ), FLUCONAZOLE (View Fluconazole Review and Fluconazole Label ), FUROSEMIDE (View Furosemide Review and Furosemide Label ), INSULIN GARGINE (View Insulin Gargine Review and Insulin Gargine Label ). Patient was hospitalized.

6170405-X | Erythema, Rash
on Apr 27, 2009 Male patient from UNITED STATES , 69 years of age, weighting 189.6 lb, was diagnosed with acute myeloid leukaemia and was treated with Clofarabine (View Usage). Patient experienced the following unwanted or unexpected effects: erythema, rash (What is rash?). Clofarabine dosage: 40mg/m2 Iv Qd X5d. During the same period patient was treated with CYTARABINE (View Cytarabine Review and Cytarabine Label ), ACYCLOVIR (View Acyclovir Review and Acyclovir Label ), ALLOPURINOL (View Allopurinol Review and Allopurinol Label ), CARBIDOPA AND LEVODOPA (View Carbidopa And Levodopa Review and Carbidopa And Levodopa Label ), DEXAMETHASONE 4MG TAB (View Dexamethasone 4mg Tab Review and Dexamethasone 4mg Tab Label ), LEVOFLOX (View Levoflox Review and Levoflox Label ), ATIVAN (View Ativan Review and Ativan Label ), MORPHINE (View Morphine Review and Morphine Label ).

6167983-3 | Convulsion, Infusion Related Reaction
Patient was taking Clofarabine (View Usage). Patient had the following side effects: convulsion, infusion related reaction on Apr 23, 2009 from UNITED STATES Additional patient health information: Female patient , weighting 155.4 lb, was diagnosed with bone marrow conditioning regimen and. Clofarabine dosage: 54mg Daily Iv Drip. During the same period patient was treated with CAMPATH (20 Mg Daily Iv Drip) (View Campath Review and Campath Label ). Patient was hospitalized.