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Clozapine Side Effects summary

Total Clozapine reports: 1305.
Clozapine FDA safety alerts: 2002 2004 2006 .
Reported deaths: 193    Reported hospitalizations: 309.
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Clozapine Poll Results

Have you experienced Clozapine side effects?
Yes, Severe55%
Yes, Mild9%
Yes, Minor18%
No18%
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Clozapine Side Effects reported on Patientsville.com

None reported at this time.

Clozapine FDA reported side effects and reactions

2008
AGRANULOCYTOSIS, COMPLETED SUICIDE, NEUTROPHIL COUNT DECREASED, ABDOMINAL PAIN, ACUTE FEBRILE NEUTROPHILIC DERMATOSIS
2007
AGRANULOCYTOSIS, ABNORMAL BEHAVIOUR, ANGIOEDEMA, BLOOD CREATINE PHOSPHOKINASE INCREASED, NEUTROPHIL COUNT DECREASED
2006
GRANULOCYTOPENIA, UNEVALUABLE EVENT, TREATMENT NONCOMPLIANCE, DEATH, PRE-EXISTING DISEASE

Clozapine Side Effects reported to FDA


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Showing 1-40 of 1305 Next >

Clozapine Side Effects Report #5198842-0
Physician from UNITED STATES reported CLOZAPINE problem on Dec 28, 2006. Female patient, 35 years of age, was diagnosed with psychotic disorder and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: cardiac failure congestive, eosinophilia, pneumonia What is  pneumonia, pulmonary oedema, pyrexia. CLOZAPINE dosage: 162.5 MG, BID. Patient was hospitalized. Patient recovered.

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Clozapine Side Effects Report #5199866-X
CLOZAPINE problem was reported by a Pharmacist from UNITED STATES on Jan 02, 2007. Male patient, 51 years of age, weighting 297.0 lb, was diagnosed with schizophrenia and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: cardiac failure congestive, dyspnoea, ejection fraction decreased, heart rate increased, myocarditis, pyrexia, sinus tachycardia, troponin increased. CLOZAPINE dosage: 50 MG AM PO 100 MG PM PO. During the same period patient was treated with OLANZAPINE, METOPRALOL, LOVASTATIN, LEVOFLOXACIN, LORAZEPAM, TRAZODONE, LOPERIMIDE, IBUPROFEN. Patient was hospitalized. Patient recovered.

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Clozapine Side Effects Report #5199895-6
Health Professional from UNITED STATES reported CLOZAPINE problem on Dec 19, 2006. Male patient, 39 years of age, was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: blood creatine phosphokinase increased, blood glucose increased, blood pressure systolic increased, faecal incontinence, hyperhidrosis, intentional overdose, loss of consciousness. CLOZAPINE dosage: unknown. Patient was hospitalized. Patient recovered.

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Clozapine Side Effects Report #5199909-3
CLOZAPINE problem was reported by a Pharmacist from UNITED STATES on Dec 22, 2006. Male patient, 63 years of age, was diagnosed with schizophrenia and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: cardiac failure congestive, pneumonia What is  pneumonia. CLOZAPINE dosage: unknown. Patient died on 12/06/2006.

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Clozapine Side Effects Report #5201390-2
Health Professional from UNITED STATES reported CLOZAPINE problem on Dec 19, 2006. Male patient, 39 years of age, was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: blood creatine phosphokinase increased, blood glucose increased, blood pressure systolic increased, electrocardiogram qt corrected interval prolonged, faecal incontinence, hyperhidrosis, intentional overdose. CLOZAPINE dosage: unknown. Patient was hospitalized. Patient recovered.

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Clozapine Side Effects Report #5201492-0
CLOZAPINE problem was reported by a Consumer or non-health professional from UNITED STATES on Dec 20, 2006. Male patient, 28 years of age, was diagnosed with schizophrenia, paranoid type and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: appendicitis What is  appendicitis, septic shock. CLOZAPINE dosage: 400 MG HS PO. During the same period patient was treated with VALPROATE, BENZTROPINE MESYLATE, LORAZEPAM. Patient died on 09/09/2006.

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Clozapine Side Effects Report #5201497-X
Health Professional from UNITED STATES reported CLOZAPINE problem on Dec 20, 2006. Male patient, 37 years of age, weighting 169.8 lb, was diagnosed with schizophrenia, paranoid type and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: bone marrow transplant, chills, cough, laboratory test abnormal, multiple myeloma What is  multiple myeloma, pyrexia, spinal compression fracture, white blood cell count decreased. CLOZAPINE dosage: 25 MG HS PO. During the same period patient was treated with SERTRALINE, LOVASTATIN, FERROUS SULPHATE, DEXAMETHASONE, THALIDOMIDE, WARFARIN. Patient was hospitalized. Patient recovered.

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Clozapine Side Effects Report #5203947-1
CLOZAPINE problem was reported by a Pharmacist from UNITED STATES on Jan 05, 2007. Male patient, 47 years of age, was diagnosed with schizophrenia and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: grand mal convulsion. CLOZAPINE dosage: unknown. Patient was hospitalized. Patient recovered.

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Clozapine Side Effects Report #5203975-6
Health Professional from UNITED STATES reported CLOZAPINE problem on Dec 27, 2006. Male patient, 39 years of age, was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: white blood cell count increased. CLOZAPINE dosage: (500 MG), ORAL. During the same period patient was treated with ARIPOPRAZOLE, LITHIUM CARBONATE. Patient died on 10/10/2006.

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Clozapine Side Effects Report #5206995-0
CLOZAPINE problem was reported by a Health Professional from INDIA on Jan 03, 2007. Male patient, 45 years of age, was diagnosed with schizophrenia and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: angioedema, blister, eye swelling, neutrophil count increased, pyrexia, rash maculo-papular, skin exfoliation, vomiting, white blood cell count increased. CLOZAPINE dosage: unknown. Patient recovered.

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Clozapine Side Effects Report #5208635-3
Health Professional from ITALY reported CLOZAPINE problem on Jan 05, 2007. Male patient, 48 years of age, weighting 172.0 lb, was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: aggression, agitation, hallucinations, mixed, salivary hypersecretion. CLOZAPINE dosage: 600 MG/DAY. During the same period patient was treated with LEVOMEPROMAZINE, VALPROIC ACID, LORAZEPAM, FLURAZEPAM, HALOPERIDOL. Patient recovered.

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Clozapine Side Effects Report #5208653-5
CLOZAPINE problem was reported by a Health Professional from INDIA on Jan 03, 2007. Male patient, 46 years of age, was diagnosed with bipolar disorder What is  bipolar disorder and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: angioedema, blister, flushing, neutrophil count increased, periorbital oedema, pyrexia, skin exfoliation, white blood cell count increased. CLOZAPINE dosage: unknown. Patient was hospitalized. Patient recovered.

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Clozapine Side Effects Report #5208929-1
Pharmacist from UNITED STATES reported CLOZAPINE problem on Jan 11, 2007. Male patient, 42 years of age, weighting 190.7 lb, was diagnosed with schizophrenia and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: heart rate irregular. CLOZAPINE dosage: 450 MG, 450 MG QD, ORAL. Patient was hospitalized. Patient recovered.

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Clozapine Side Effects Report #5212913-1
CLOZAPINE problem was reported by a Health Professional from SPAIN on Jan 09, 2007. Female patient, 52 years of age, was diagnosed with depression What is  depression and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, agitation, amimia, anxiety What is  anxiety, bradykinesia, delusion, depressed mood, depression What is  depression. CLOZAPINE dosage: unknown. During the same period patient was treated with CLOMIPRAMINE, IMIPRAMINE, OLANZAPINE, LORAZEPAM, LAMOTRIGINE, QUETIAPINE FUMARATE. Patient was hospitalized. Patient recovered.

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Clozapine Side Effects Report #5213883-2
Consumer or non-health professional from UNITED STATES reported CLOZAPINE problem on Jan 03, 2007. Male patient, 56 years of age, was treated with CLOZAPINE. CLOZAPINE dosage: 50 MG;QD;PO. During the same period patient was treated with METOCLOPRAMIDE, TEGASEROD, ISOSORBIDE DINITRATE, SENNA ALEXANDRINA, SIMETHICONE. Patient died on 07/27/2006.

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Clozapine Side Effects Report #5214369-1
CLOZAPINE problem was reported by a Pharmacist from UNITED STATES on Jan 02, 2007. Male patient, 68 years of age, was treated with CLOZAPINE. CLOZAPINE dosage: unknown. Patient died on 12/03/2006.

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Clozapine Side Effects Report #5214876-1
Pharmacist from UNITED STATES reported CLOZAPINE problem on Jan 22, 2007. Male patient, weighting 282.0 lb, was diagnosed with schizoaffective disorder and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: priapism, pyrexia. CLOZAPINE dosage: 150 MG DAILY PO. During the same period patient was treated with ZYPREXA. Patient was hospitalized. Patient recovered.

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Clozapine Side Effects Report #5215563-6
CLOZAPINE problem was reported by a Consumer or non-health professional from INDIA on Jan 18, 2007. Male patient, 45 years of age, was diagnosed with schizophrenia and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: blood bicarbonate decreased, blood chloride decreased, blood creatinine decreased, blood glucose increased, blood lactic acid decreased, blood ph decreased, blood potassium decreased, blood sodium decreased, blood urea decreased. CLOZAPINE dosage: unknown. During the same period patient was treated with RISPERIDONE. Patient died.

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Clozapine Side Effects Report #5221835-1
Consumer or non-health professional from UNITED STATES reported CLOZAPINE problem on Jan 24, 2007. Male patient, 42 years of age, weighting 301.0 lb, was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: diabetes mellitus, myocardial infarction, weight increased. CLOZAPINE dosage: unknown. During the same period patient was treated with RISPERIDONE, CLOMIPRAMINE, FLUOXETINE, NAPROXEN, ZYPREXA. Patient died on 09/09/2003.

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Clozapine Side Effects Report #5223148-0
CLOZAPINE problem was reported by a Physician from INDIA on Jan 17, 2007. Male patient, 46 years of age, was diagnosed with bipolar disorder What is  bipolar disorder and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: angioedema, blister, flushing, hypersensitivity, periorbital oedema, pyrexia, skin exfoliation. CLOZAPINE dosage: 50 MG, QD,. Patient recovered.

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Clozapine Side Effects Report #5224934-3
Physician from INDIA reported CLOZAPINE problem on Jan 17, 2007. Male patient, 45 years of age, was diagnosed with schizophrenia and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: angioedema, blister, hereditary angioedema, neutrophil percentage increased, pyrexia, rash maculo-papular, skin exfoliation, vomiting, white blood cell count increased. CLOZAPINE dosage: unknown. During the same period patient was treated with PHENIRAMINE. Patient recovered.

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Clozapine Side Effects Report #5225068-4
CLOZAPINE problem was reported by a Pharmacist from UNITED STATES on Jan 11, 2007. Male patient, 39 years of age, weighting 181.0 lb, was diagnosed with schizoaffective disorder and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: pneumonia aspiration. CLOZAPINE dosage: 700 MG;AT BEDTIME;ORAL. During the same period patient was treated with DIVALPROEX, DULOXETINE, DIPHENHYDRAMINE, LAMOTRIGINE. Patient was hospitalized. Patient recovered.

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Clozapine Side Effects Report #5225764-9
Pharmacist from UNITED STATES reported CLOZAPINE problem on Jan 31, 2007. Female patient, weighting 121.0 lb, was diagnosed with schizoaffective disorder and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: myocarditis. CLOZAPINE dosage: unknown. Patient recovered.

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Clozapine Side Effects Report #5225873-4
CLOZAPINE problem was reported by a Pharmacist from UNITED STATES on Jan 30, 2007. Female patient, weighting 157.0 lb, was diagnosed with schizophrenia and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: neutrophil count decreased, white blood cell count decreased. CLOZAPINE dosage: unknown. During the same period patient was treated with SEROQUEL. Patient was hospitalized. Patient recovered.

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Clozapine Side Effects Report #5226905-X
Physician from INDIA reported CLOZAPINE problem on Jan 19, 2007. Female patient, 18 years of age, was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: eye rolling, oculogyration, treatment noncompliance. CLOZAPINE dosage: 25 MG-300 MG/DAY. Patient recovered.

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Clozapine Side Effects Report #5231267-8
CLOZAPINE problem was reported by a Health Professional from UNITED STATES on Feb 05, 2007. Female patient, weighting 177.0 lb, was diagnosed with contraception and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: thrombosis. CLOZAPINE dosage: 25 MG TWO DAILY PO. During the same period patient was treated with ORTHO EVRA. Patient was hospitalized. Patient recovered.

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Clozapine Side Effects Report #5237848-X
Consumer or non-health professional from UNITED KINGDOM reported CLOZAPINE problem on Feb 09, 2007. Female patient, 40 years of age, was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: constipation What is  constipation, diarrhoea, hypoalbuminaemia, leukocytosis, nasopharyngitis, neutrophilia, pericardial effusion, pleural effusion, pyrexia. CLOZAPINE dosage: 125 MG, BID. During the same period patient was treated with OLANZAPINE. Patient was hospitalized. Patient recovered.

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Clozapine Side Effects Report #5239507-6
CLOZAPINE problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Feb 09, 2007. Female patient, 40 years of age, was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: constipation What is  constipation, diarrhoea, hypoalbuminaemia, leukocytosis, nasopharyngitis, neutrophilia, pericardial effusion, pleural effusion, pyrexia. CLOZAPINE dosage: 125 MG, BID. During the same period patient was treated with OLANZAPINE. Patient was hospitalized. Patient recovered.

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Clozapine Side Effects Report #5239509-X
Consumer or non-health professional from GERMANY reported CLOZAPINE problem on Feb 12, 2007. Male patient, weighting 204.1 lb, was diagnosed with schizophrenia and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: blood alcohol increased, eosinophilic myocarditis, influenza like illness, therapeutic agent urine positive, urine cannabinoids increased. CLOZAPINE dosage: UP TO 200 MG/DAY. During the same period patient was treated with ZYPREXA, CIPRALEX, PIRENZEPINE. Patient died.

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Clozapine Side Effects Report #5240411-8
CLOZAPINE problem was reported by a Physician from GERMANY on Feb 05, 2007. Male patient, 53 years of age, was diagnosed with schizophrenia, sleep disorder and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: atelectasis, pleural effusion, pleural fibrosis, pleurisy. CLOZAPINE dosage: UP TO 250 MG/DAY. During the same period patient was treated with PIPAMPERONE, VALPROIC ACID, CHLORPROTHIXENE, PROTHIPENDYL. Patient was hospitalized. Patient recovered.

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Clozapine Side Effects Report #5243900-5
Physician from YUGOSLAVIA reported CLOZAPINE problem on Feb 08, 2007. Female patient, 66 years of age, weighting 154.3 lb, was diagnosed with schizoaffective disorder and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: pancytopenia. CLOZAPINE dosage: 300 MG/DAY. Patient recovered.

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Clozapine Side Effects Report #5243909-1
CLOZAPINE problem was reported by a Physician from GERMANY on Feb 09, 2007. Female patient was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: gastrointestinal infection, lymphopenia, neutrophilia. CLOZAPINE dosage: 225 MG/DAY. Patient recovered.

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Clozapine Side Effects Report #5243918-2
Physician from GERMANY reported CLOZAPINE problem on Feb 08, 2007. Male patient was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: accidental exposure, bronchopneumonia, dyspnoea, fatigue. CLOZAPINE dosage: 100 MG/DAY. Patient recovered.

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Clozapine Side Effects Report #5245049-4
CLOZAPINE problem was reported by a Health Professional from HUNGARY on Feb 12, 2007. Male patient, 62 years of age, was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: abdominal distension, abdominal symptom, aggression, agitation, anxiety What is  anxiety, blood creatinine increased, blood urea increased, cardiac failure, erysipelas. CLOZAPINE dosage: 150 MG/DAY. During the same period patient was treated with HALOPERIDOL, OLANZAPINE, LEVOMEPROMAZINE, AMOBARBITAL, MEPROBAMATE, CLONAZEPAM. Patient was hospitalized. Patient recovered.

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Clozapine Side Effects Report #5245843-X
Physician from UNITED STATES reported CLOZAPINE problem on Feb 09, 2007. Female patient, 74 years of age, was diagnosed with psychotic disorder and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: fall, hip fracture, lethargy, leukocytosis, oral intake reduced. CLOZAPINE dosage: (75 MG), ORAL. During the same period patient was treated with DOCUSATE, CALCIUM CARBONATE, ASCORBIC ACID, SENNA ALEXANDRINA, FLUDROCORTISONE ACETATE, FOLIC ACID, LEVOTHYROXINE, LISINOPRIL. Patient was hospitalized. Patient died on 12/31/2006.

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Clozapine Side Effects Report #5247450-1
CLOZAPINE problem was reported by a Pharmacist from UNITED STATES on Feb 23, 2007. Female patient, 61 years of age, weighting 125.7 lb, was diagnosed with bipolar disorder What is  bipolar disorder and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: cardiomyopathy What is  cardiomyopathy, ejection fraction decreased, eosinophilia, gait disturbance, grip strength decreased, incontinence, liver function test abnormal, oedema peripheral, photophobia. CLOZAPINE dosage: 100MG BID PO. Patient died on 02/09/2007.

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Clozapine Side Effects Report #5247560-9
Physician from FRANCE reported CLOZAPINE problem on Feb 14, 2007. Female patient was diagnosed with acute tonsillitis and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: acute tonsillitis, neutropenia. CLOZAPINE dosage: 200 MG, QD. During the same period patient was treated with NUREFLEX, DEPAKOTE. Patient recovered.

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Clozapine Side Effects Report #5253967-6
CLOZAPINE problem was reported by a Pharmacist from UNITED STATES on Feb 28, 2007. Male patient, weighting 124.4 lb, was diagnosed with dementia What is  dementia and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: aspiration, brain natriuretic peptide increased, dysphagia, hypotension, mitral valve incompetence. CLOZAPINE dosage: 37.5 MG QHS NGT OR PO. During the same period patient was treated with CIPRO, REMERON, MIRALAX, DEPAKENE, MEGACE, COREG, LISINOPRIL. Patient was hospitalized. Patient recovered.

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Clozapine Side Effects Report #5254698-9
Consumer or non-health professional from UNITED STATES reported CLOZAPINE problem on Feb 22, 2007. Female patient was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: neoplasm malignant, white blood cell count decreased. CLOZAPINE dosage: unknown. Patient recovered.

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Clozapine Side Effects Report #5253316-3
CLOZAPINE problem was reported by a Consumer or non-health professional from SWITZERLAND on Feb 16, 2007. Female patient was diagnosed with delusional disorder, persecutory type, hypertension and was treated with CLOZAPINE. After drug was administered, patient experienced the following problems/side effects: asthenia, electroencephalogram abnormal, somnolence. CLOZAPINE dosage: 100 MG/DAY. During the same period patient was treated with TEMESTA, CHLORAZIN, NORVASC. Patient was hospitalized. Patient recovered.

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, Clozapine was diagnosed with psychotic disorder and Clozapine was diagnosed with schizophrenia and Clozapine