Comtan Side Effects
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Comtan Safety Reports reported to FDA
Total Comtan reports: 124.Comtan FDA safety alerts: No.
Reported deaths: 14 Reported hospitalizations: 55.
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Reported Comtan Side Effects: pyrexia, hallucination, interstitial lung disease, dyspnoea, fall, hallucination, visual, neuroleptic malignant syndrome, pneumonia, blood pressure increased, pneumonia aspiration, muscle rigidity.
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Showing 1-50 of 124 Next >
Comtan Side Effects Report #5075051-7Consumer or non-health professional from UNITED STATES reported COMTAN problem on July 21, 2006. Male patient, 57 years of age, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: blister, chromaturia, eosinophilic pneumonia, hyperhidrosis, muscular weakness, pneumothorax, urine odour abnormal. COMTAN dosage: 200 MG, SIX TO EIGHT MONTHS AGO. During the same period patient was treated with SELEGILINE, SINEMET. Patient was hospitalized. Patient recovered.
Comtan Side Effects Report #5075753-2
COMTAN problem was reported by a Consumer or non-health professional from BRAZIL on July 25, 2006. Female patient, 14 years of age, was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: suicide attempt. COMTAN dosage: 800 MG ONCE ORAL. Patient recovered.
Comtan Side Effects Report #5079340-1
Physician from SWITZERLAND reported COMTAN problem on May 05, 2006. Male patient, 62 years of age, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: anxiety, condition aggravated, hallucination, visual, musculoskeletal stiffness. COMTAN dosage: 200 MG, 5QD. During the same period patient was treated with MADOPAR, MADOPAR CR, MADOPAR CR, MADOPAR CR, REQUIP, DETRUSITOL RETARD, SEROQUEL. Patient was hospitalized. Patient recovered.
Comtan Side Effects Report #5084820-9
COMTAN problem was reported by a Consumer or non-health professional from CANADA on July 27, 2006. Male patient, 79 years of age, was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: delusion, paranoia. COMTAN dosage: 400 MG (100 MG, 4 IN 1 D). During the same period patient was treated with EXELON, SINEMET CR, LEVODOPA, ZYPREXA, WELLBUTRIN. Patient recovered.
Comtan Side Effects Report #5089421-4
Consumer or non-health professional from SWITZERLAND reported COMTAN problem on Aug 04, 2006. Male patient, 62 years of age, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: anxiety, condition aggravated, hallucination, musculoskeletal stiffness, nocturia. COMTAN dosage: 1000 MG (200 MG, 5 IN 1 D). During the same period patient was treated with MADOPAR, MADOPAR CR, MADOPAR CR, REQUIP, DETRUSITOL RETARD, SEROQUEL, CHLORALDURAT, TEMESTA. Patient was hospitalized. Patient recovered.
Comtan Side Effects Report #5089422-6
COMTAN problem was reported by a Consumer or non-health professional from FRANCE on Aug 11, 2006. Female patient, 76 years of age, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: brain natriuretic peptide increased, mitral valve disease, mitral valve incompetence, pulmonary hypertension, pyrexia. COMTAN dosage: unknown. During the same period patient was treated with MODOPAR, REQUIP. Patient was hospitalized. Patient recovered.
Comtan Side Effects Report #5090828-X
Consumer or non-health professional from CANADA reported COMTAN problem on Aug 10, 2006. Female patient, 72 years of age, was diagnosed with hallucination, parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: hallucination, refusal of treatment by patient. COMTAN dosage: 600 MG (200 MG, 3 IN 1 D) ORAL. During the same period patient was treated with LEVODOPA, LOPRESSOR, AMANTADINE, ASPIRIN, TEGRETOL. Patient recovered.
Comtan Side Effects Report #5090895-3
COMTAN problem was reported by a Pharmacist from AUSTRALIA on Aug 07, 2005. Female patient was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: hallucination. COMTAN dosage: 200 MG; 100 MG. During the same period patient was treated with SINEMET. Patient recovered.
Comtan Side Effects Report #5095235-1
Physician from UNITED STATES reported COMTAN problem on Aug 25, 2006. Female patient, 71 years of age, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: blood pressure increased, hot flush. COMTAN dosage: 100 MG, QID. Patient recovered.
Comtan Side Effects Report #5095237-5
COMTAN problem was reported by a Pharmacist from UNITED STATES on Aug 25, 2006. Female patient, 83 years of age, weighting 79.99 lb, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: convulsion, delirium, delusion, dyskinesia, hallucination, muscle rigidity, nightmare, parkinsonism, tremor. COMTAN dosage: 200 MG, QID. During the same period patient was treated with AMANTADINE, SINEMET, MIRAPEX, PARCOPA. Patient was hospitalized. Patient recovered.
Comtan Side Effects Report #5095251-X
Consumer or non-health professional from FRANCE reported COMTAN problem on Aug 28, 2006. Male patient, 66 years of age, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: agitation, cardiac arrest, confusional state, cyanosis, dyskinesia, loss of consciousness, musculoskeletal stiffness, neurological symptom. COMTAN dosage: unknown. During the same period patient was treated with MODOPAR, TRIVASTAL, STABLON, PAROXETINE HYDROCHLORIDE, STALEVO. Patient died on 07/05/2006.
Comtan Side Effects Report #5102090-X
COMTAN problem was reported by a Consumer or non-health professional from FRANCE on Sept 04, 2006. Female patient, 81 years of age, weighting 132.3 lb, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: blood pressure increased, confusional state, creatinine renal clearance decreased, extrapyramidal disorder, fall, hypertonia, pyrexia. COMTAN dosage: 400 MG DAILY. During the same period patient was treated with MODOPAR, DOLIPRANE, PRAZEPAM, STABLON, ANAFRANIL, DITROPAN, XANAX, VASTAREL. Patient was hospitalized. Patient recovered.
Comtan Side Effects Report #5109012-6
Health Professional from JAPAN reported COMTAN problem on Sept 01, 2006. Female patient, 64 years of age, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: anorexia, disease progression, gait disturbance, insomnia, on and off phenomenon, palpitations. COMTAN dosage: 300 MG (100 MG, 3 IN 1 D), ORAL. During the same period patient was treated with ALOSENN, LENDORMIN, HICEE, THYRADIN, NEODOPASOL, SIFROL. Patient was hospitalized. Patient recovered.
Comtan Side Effects Report #5110727-4
COMTAN problem was reported by a Consumer or non-health professional from UNITED STATES on Sept 01, 2006. Female patient, 70 years of age, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: blood pressure increased, hot flush. COMTAN dosage: 800 MG, 4 IN 1 D, ORAL (SEE IMAGE). Patient recovered.
Comtan Side Effects Report #5110728-6
Consumer or non-health professional from UNITED STATES reported COMTAN problem on Sept 01, 2006. Female patient, 83 years of age, weighting 79.98 lb, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: condition aggravated, convulsion, delirium, delusion, hallucination, nightmare, parkinsonism. COMTAN dosage: 800 MG, 4 IN 1 D, ORAL. During the same period patient was treated with AMANTADINE, SINEMET, MIRAPEX, PARCOPA. Patient was hospitalized. Patient recovered.
Comtan Side Effects Report #5112748-4
COMTAN problem was reported by a Consumer or non-health professional from JAPAN on Sept 01, 2006. Male patient, 55 years of age, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: condition aggravated, dyskinesia, haemorrhage, inguinal hernia, post procedural haematoma, procedural pain, pyrexia, scrotal haematocoele. COMTAN dosage: 800 MG ORAL. During the same period patient was treated with PARLODEL, PURSENNID, NEO DOPASTON, CABASER, ARTANE, PERMAX, SELEGILINE HYDROCHLORIDE, POLLAKISU. Patient was hospitalized. Patient recovered.
Comtan Side Effects Report #5114133-8
Physician from SPAIN reported COMTAN problem on Sept 12, 2006. Male patient, 68 years of age, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: blood creatine phosphokinase increased, infection, intubation, muscle contracture, neuroleptic malignant syndrome, pyrexia, tremor. COMTAN dosage: unknown. During the same period patient was treated with SINEMET, PRAMIPEXOLE DIHYDROCHLORIDE, ARTANE, AMANTADINE, ENALAPRIL, OMEPRAZOLE, BRONCHODILATORS, AMITRIPTYLINE. Patient was hospitalized. Patient recovered.
Comtan Side Effects Report #5114955-3
COMTAN problem was reported by a Consumer or non-health professional from BRAZIL on Sept 11, 2006. Male patient, 66 years of age, weighting 198.4 lb, was diagnosed with parkinson's disease, hypertension and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: arthralgia, tremor. COMTAN dosage: 600 MG/DAY. During the same period patient was treated with PROLOPA, LODIPIL, SELEGILINE HYDROCHLORIDE. Patient was hospitalized. Patient recovered.
Comtan Side Effects Report #5119277-2
Consumer or non-health professional from UNITED STATES reported COMTAN problem on Sept 16, 2006. Female patient was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: blood pressure fluctuation, body temperature fluctuation, muscle rigidity, serotonin syndrome. COMTAN dosage: 800 MG, 4 IN 1 D, ORAL. During the same period patient was treated with SINEMET. Patient recovered.
Comtan Side Effects Report #5119912-9
COMTAN problem was reported by a Consumer or non-health professional from FRANCE on Sept 12, 2006. Female patient, 81 years of age, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: blood pressure systolic increased, confusional state, creatinine renal clearance decreased, extrapyramidal disorder, fall, hypertonia, pyrexia. COMTAN dosage: 400 MG ORAL. During the same period patient was treated with DOLIPRANE, PRAZEPAM, STABLON, ANAFRANIL, DITROPAN, XANAX, VASTAREL, SEGLOR. Patient was hospitalized. Patient recovered.
Comtan Side Effects Report #5119913-0
Consumer or non-health professional from FRANCE reported COMTAN problem on Sept 13, 2006. Male patient, 80 years of age, was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: bacteraemia, creatinine renal clearance decreased, diarrhoea, urinary tract infection. COMTAN dosage: unknown. During the same period patient was treated with STABLON, TRIVASTAL, SINEMET. Patient was hospitalized. Patient recovered.
Comtan Side Effects Report #5118475-1
COMTAN problem was reported by a Consumer or non-health professional from FRANCE on Sept 18, 2006. Male patient, 71 years of age, was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: anaemia, anxiety, dyspnoea, leukaemia, sinus arrhythmia. COMTAN dosage: 600 MG/DAY. During the same period patient was treated with PARLODEL, EFFERALGAN, MODOPAR, URBANYL. Patient was hospitalized. Patient recovered.
Comtan Side Effects Report #5119534-X
Consumer or non-health professional from UNITED STATES reported COMTAN problem on July 13, 2006. Male patient, 57 years of age, weighting 155.0 lb, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: blister, blood immunoglobulin e increased, chromaturia, dyspnoea, eosinophil count increased, eosinophilic pneumonia, feeling hot, hyperhidrosis, malaise. COMTAN dosage: 200 MG, QD. During the same period patient was treated with SELEGILINE, SINEMET, PARCOPA. Patient was hospitalized. Patient recovered.
Comtan Side Effects Report #5120207-8
COMTAN problem was reported by a Pharmacist from UNITED STATES on Oct 02, 2006. Female patient, 75 years of age, weighting 121.3 lb, was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: agitation, conversion disorder, depersonalisation, hallucination, regressive behaviour. COMTAN dosage: unknown. During the same period patient was treated with TYLENOL. Patient recovered.
Comtan Side Effects Report #5126620-7
Consumer or non-health professional from FRANCE reported COMTAN problem on Oct 02, 2006. Male patient, 80 years of age, was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: anorexia, confusional state, disorientation, dyskinesia, fall, mutism. COMTAN dosage: 1200 MG/DAY. During the same period patient was treated with MODOPAR, LASIX, ASPIRIN, POTASSIUM CHLORIDE, IKOREL. Patient was hospitalized. Patient recovered.
Comtan Side Effects Report #5127616-1
COMTAN problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 05, 2006. Female patient, 69 years of age, weighting 218.0 lb, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, alopecia, balance disorder, coordination abnormal, dizziness, dyspepsia, dysphagia, fall, head discomfort. COMTAN dosage: 200 MG, TID. During the same period patient was treated with LEVOXYL, SINEMET CR, AMANTADINE, CALCIUM GLUCONATE, JOINT FOOD, VITAMINS NOS. Patient was hospitalized. Patient recovered.
Comtan Side Effects Report #5129952-1
Consumer or non-health professional from SPAIN reported COMTAN problem on Sept 22, 2006. Male patient, 68 years of age, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: infection, neuroleptic malignant syndrome. COMTAN dosage: unknown. During the same period patient was treated with SINEMET, PRAMIPEXOLE DIHYDROCHLORIDE, ARTANE, AMANTADINE, ENALAPRIL MALEATE, OMEPRAZOLE, BRONCHODILATORS, AMITRIPTYLINE. Patient was hospitalized. Patient recovered.
Comtan Side Effects Report #5129953-3
COMTAN problem was reported by a Consumer or non-health professional from BRAZIL on Sept 26, 2006. Male patient, 66 years of age, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: arthralgia, tremor. COMTAN dosage: 600 MG ORAL. During the same period patient was treated with PROLOPA, LOPIDIL, SELEGILINE. Patient was hospitalized. Patient recovered.
Comtan Side Effects Report #5132217-5
Consumer or non-health professional from UNITED STATES reported COMTAN problem on Oct 02, 2006. Male patient, 57 years of age, weighting 155.0 lb, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: blister, chromaturia, eosinophilic pneumonia, hyperhidrosis, iatrogenic injury, muscular weakness, pneumothorax, procedural complication. COMTAN dosage: 200 MG QD. During the same period patient was treated with SELEGILINE, SINEMET, PARCOPA. Patient was hospitalized. Patient recovered.
Comtan Side Effects Report #5132218-7
COMTAN problem was reported by a Consumer or non-health professional from UNITED STATES on Oct 07, 2006. Male patient, 68 years of age, was diagnosed with parkinson's disease, dementia and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: confusional state, hallucination, hyperhidrosis. COMTAN dosage: 200 MG, 1 IN 1 D. During the same period patient was treated with NAMENDA, SINEMET, COUMADIN, ZOLOFT. Patient recovered.
Comtan Side Effects Report #5132491-5
Consumer or non-health professional from GREECE reported COMTAN problem on Oct 09, 2006. Female patient, 52 years of age, was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: pancreatic cyst. COMTAN dosage: unknown. Patient recovered.
Comtan Side Effects Report #5132960-8
COMTAN problem was reported by a Consumer or non-health professional from FRANCE on Sept 30, 2006. Male patient, 71 years of age, was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: anxiety, dyspnoea, leukaemia, sinus arrhythmia. COMTAN dosage: 600 MG ORAL. During the same period patient was treated with PARLODEL, EFFERALGAN, MODOPAR, MODOPAR LP, URBANYL. Patient was hospitalized. Patient recovered.
Comtan Side Effects Report #5142089-0
Consumer or non-health professional from GREECE reported COMTAN problem on Oct 09, 2006. Female patient, 52 years of age, was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: pancreatic cyst. COMTAN dosage: unknown. Patient recovered.
Comtan Side Effects Report #5163804-6
COMTAN problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 02, 2006. Male patient was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: depression, muscle twitching. COMTAN dosage: unknown. Patient recovered.
Comtan Side Effects Report #5165637-3
Consumer or non-health professional from GREECE reported COMTAN problem on Nov 02, 2006. Female patient, 52 years of age, was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: pancreatic cyst. COMTAN dosage: unknown. Patient recovered.
Comtan Side Effects Report #5165639-7
COMTAN problem was reported by a Consumer or non-health professional from CANADA on Nov 02, 2006. Female patient, 88 years of age, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: hallucination, insomnia, memory impairment. COMTAN dosage: 200MG QID ORAL. During the same period patient was treated with LEVODOPA, SINEMET, ENTERIC ASPIRIN, TRAZODONE. Patient recovered.
Comtan Side Effects Report #5170561-6
Consumer or non-health professional from CANADA reported COMTAN problem on Nov 17, 2006. Male patient, 83 years of age, was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: hallucination, poor quality sleep. COMTAN dosage: unknown. During the same period patient was treated with LEVODOPA. Patient recovered.
Comtan Side Effects Report #5194516-0
COMTAN problem was reported by a Consumer or non-health professional from BRAZIL on Dec 08, 2006. Male patient, 35 years of age, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: arthralgia, back pain, confusional state, dyspnoea, gastrointestinal motility disorder, muscle rigidity. COMTAN dosage: 200MG, Q6H ORAL. During the same period patient was treated with CARBIDOPA AND LEVODOPA, AMANTADINE. Patient recovered.
Comtan Side Effects Report #5386252-2
Physician from JAPAN reported COMTAN problem on July 11, 2007. Female patient, 77 years of age, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: dyspnoea, interstitial lung disease, wheezing. COMTAN dosage: 200 MG/D. During the same period patient was treated with MENESIT. Patient recovered.
Comtan Side Effects Report #5386438-7
COMTAN problem was reported by a Consumer or non-health professional from JAPAN on June 19, 2007. Male patient, 70 years of age, was diagnosed with parkinson's disease, back pain and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: disseminated intravascular coagulation, fungal infection, gastritis erosive, gastritis haemorrhagic, neuroleptic malignant syndrome, oesophagitis haemorrhagic, pneumonia aspiration, reflux oesophagitis, sepsis. COMTAN dosage: 400 MG. During the same period patient was treated with HYPEN, MARZULENE S, NEO DOPASTON, CABASER, METHYCOBAL, SYMMETREL, HARNAL, LENDORMIN. Patient was hospitalized. Patient recovered.
Comtan Side Effects Report #5388656-0
Consumer or non-health professional from BRAZIL reported COMTAN problem on June 26, 2007. Female patient, 80 years of age, was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: muscle rigidity, paralysis. COMTAN dosage: 200MG QD, ORAL. During the same period patient was treated with PROLOPA. Patient recovered.
Comtan Side Effects Report #5388938-2
COMTAN problem was reported by a Consumer or non-health professional from BRAZIL on July 06, 2007. Male patient, 71 years of age, weighting 167.6 lb, was diagnosed with parkinson's disease, hypertension and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: blood pressure increased, feeling hot. COMTAN dosage: 200 MG/D. During the same period patient was treated with CARBIDOPA, LEVODOPA, SELEGILINE, ENALAPRIL MALEATE, VITAMIN B. Patient recovered.
Comtan Side Effects Report #5388979-5
Physician from JAPAN reported COMTAN problem on July 05, 2007. Male patient, 70 years of age, weighting 127.9 lb, was diagnosed with parkinson's disease, tremor and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: eating disorder, fluid replacement, pyrexia, tremor. COMTAN dosage: 100 MG, 5QD. During the same period patient was treated with LEVODOPA, MENESIT, RIVOTRIL, ARTANE, GASMOTIN. Patient recovered.
Comtan Side Effects Report #5389856-6
COMTAN problem was reported by a Physician from JAPAN on July 09, 2007. Female patient was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: cough, eye pain, interstitial lung disease, pneumonia, productive cough, rhinalgia, rhinorrhoea, vitreous floaters. COMTAN dosage: 400 MG7D. During the same period patient was treated with ADONA, DEPAS. Patient was hospitalized. Patient recovered.
Comtan Side Effects Report #5391406-5
Consumer or non-health professional from BRAZIL reported COMTAN problem on July 12, 2007. Female patient, 80 years of age, weighting 97.00 lb, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: hypokinesia, muscle rigidity, paralysis. COMTAN dosage: 200 MG, QD. During the same period patient was treated with PROLOPA, SIFROL. Patient recovered.
Comtan Side Effects Report #5401407-6
COMTAN problem was reported by a Consumer or non-health professional from FRANCE on July 30, 2007. Male patient, 70 years of age, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: bleeding time prolonged, cerebral haematoma, cerebral haemorrhage, coagulopathy, deep brain stimulation, incision site haemorrhage, mydriasis, pupils unequal. COMTAN dosage: unknown. During the same period patient was treated with FLURBIPROFEN, PAROXETINE, SINEMET, REQUIP, MODOPAR, IMOVANE, MOTILIUM. Patient was hospitalized. Patient died.
Comtan Side Effects Report #5405680-X
Physician from JAPAN reported COMTAN problem on July 31, 2007. Female patient, 77 years of age, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: c-reactive protein increased, chest x-ray abnormal, dyspnoea, eosinophilia, interstitial lung disease, oxygen saturation decreased, pyrexia, respiratory disorder, respiratory failure. COMTAN dosage: 200 MG/D. During the same period patient was treated with MENESIT, FLUVOXAMINE MALEATE, CLONAZEPAM, PERMAX, ARICEPT, SIFROL, MAGLAX. Patient recovered.
Comtan Side Effects Report #5405998-0
COMTAN problem was reported by a Consumer or non-health professional from BRAZIL on July 18, 2007. Male patient, 71 years of age, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: blood pressure fluctuation, blood pressure increased, feeling hot. COMTAN dosage: 200 MG ORAL. During the same period patient was treated with LEVODOPA, CARBIDOPA, SELEGILINE, ENALAPRIL MALEATE, VITAMIN B. Patient recovered.
Comtan Side Effects Report #5406001-9
Consumer or non-health professional from JAPAN reported COMTAN problem on July 14, 2007. Female patient, 77 years of age, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: interstitial lung disease. COMTAN dosage: 200 MG ORAL. During the same period patient was treated with MENESIT. Patient recovered.
Comtan Side Effects Report #5406002-0
COMTAN problem was reported by a Consumer or non-health professional from BRAZIL on July 19, 2007. Female patient, 80 years of age, was diagnosed with parkinson's disease and was treated with COMTAN. After drug was administered, patient experienced the following problems/side effects: muscle rigidity, paralysis. COMTAN dosage: 200MG QD ORAL. During the same period patient was treated with PROLOPA. Patient recovered.
Showing 1-50 of 124 Next >
Drug Information: Entacapone
URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601236.html
(en ta' ka pone)Why is this medication prescribed?
Entacapone is an inhibitor of catechol-O-methyltransferase (COMT). It is used in combination with levodopa and carbidopa (Sinemet) to treat the end-of-dose 'wearing-off' symptoms of Parkinson's disease. Entacapone helps the levodopa and carbidopa work better by allowing more of it to reach the brain, where it has its effects.
This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
How should this medicine be used?
Entacapone comes as a tablet to take by mouth. It is taken with every dose of levodopa and carbidopa, up to 8 times a day. Entacapone may be taken with or without food. Read your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take entacapone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Entacapone helps control the symptoms of Parkinson's disease, but it does not cure it. Continue to take entacapone even if you feel well. Do not stop taking entacapone without talking to your doctor. Stopping entacapone suddenly may make your Parkinson's disease worse and could have other dangerous effects. Your doctor probably will decrease your dose gradually if necessary.
What special precautions should I follow?
Before taking entacapone,
- tell your doctor and pharmacist if you are allergic to entacapone or any other drugs.
- tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially ampicillin, apomorphine (Zydis), bitolterol (Tornalate), chloramphenicol (AK-Chlor, Chloromycetin), cholestyramine (Cholybar, Questran, Questran Light, others), medications that cause drowsiness (including medications for anxiety and sleeping pills), dobutamine (Dobutrex), epinephrine (AsthmaHaler, EpiPen Auto-Injector, Primatene Mist, others), erythromycin (E-Base, E.E.S., E-Mycin, others), isoetharine (Arm-a-Med Isoetharine, Beta-2, Bronkometer, others), isoproterenol (Dispos-a-Med Isoproterenol, Isuprel, Medihaler-Iso, others), methyldopa (Aldomet), phenelzine (Nardil), probenecid (Benemid), rifampin (Rifadin, Rimactane), tranylcypromine (Parnate), and vitamins and herbal products.
- tell your doctor if you have or have ever had liver disease or a history of alcoholism.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking entacapone, call your doctor.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking entacapone.
- you should know that this medication may make you drowsy. Do not drive a car or operate heavy machinery until you know how entacapone affects you.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed dose.
What side effects can this medication cause?
Entacapone may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- dizziness
- diarrhea
- upset stomach
- movements you cannot control
- stomach pain
- drowsiness
If you experience any of the following symptoms, call your doctor immediately:
- difficulty breathing
- hallucinations
- high fever
- confusion
- muscle stiffness
- weakness with or without a fever
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].
What storage conditions are needed for this medicine?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
What other information should I know?
Keep all appointments with your doctor and the laboratory.You may become dizzy when you get up after sitting or lying down, especially when you begin taking entacapone. To avoid this problem, make sure to get up slowly, especially if you have been sitting or lying down for a long time.
Entacapone may cause your urine to change to a brownish-orange color. This effect is common and is not harmful.
Do not let anyone else take your medicine. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
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