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Increased Bilirubin (1)
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Defibrotide adverse events reported to FDA.

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Summary

FDA Adverse Reports: 4. View All

Defibrotide FDA safety alerts: No

Reported deaths: 2

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1Increased Bilirubin
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Often additional risks of using a medication, such as Defibrotide, become known after product is used by a larger number of patients, for a longer period of time, and by patients with different health characteristics from those studied before drug approval. This page allows You to Find answers and discuss health symptoms with other Defibrotide users, Learn more about unwanted side effects & find ways to reduce them. Browse Defibrotide Adverse Reports reported to FDA and participate in Defibrotide discussion, find alternative treatments and find ways to avoid or reduce risks associated with using Defibrotide. You can also Post a question to users community or Ask a Doctor. PatientsVille.com is Your Complete Guide to all common, undocumented and undisclosed side effects associated with drugs and vaccines. Browse More Drug Reports Here: A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

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Defibrotide Adverse Effect Reports (FDA)

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5771962-5 | Dialysis, Renal Failure Acute
on Jun 12, 2008 Female patient from UNITED STATES , 26 years of age, weighting 154.3 lb, was diagnosed with venoocclusive liver disease and was treated with Defibrotide (View Usage). Patient experienced the following unwanted or unexpected effects: dialysis (What is dialysis?), renal failure acute. Defibrotide dosage: 460 Mg Every 6 Hours Iv Drip. During the same period patient was treated with GANCICLOVIR (View Ganciclovir Review and Ganciclovir Label ), LACTULOSE (View Lactulose Review and Lactulose Label ), METHADONE HCL (View Methadone Hcl Review and Methadone Hcl Label ), SOLU MEDROL (View Solu-medrol Review and Solu-medrol Label ), MICAFUNGIN (View Micafungin Review and Micafungin Label ), MYCOPHENOLATE MOFETIL (View Mycophenolate Mofetil Review and Mycophenolate Mofetil Label ), ZOSYN (View Zosyn Review and Zosyn Label ), SEROQUEL (View Seroquel Review and Seroquel Label ).

4955795-5 | Blood Pressure Decreased, Bradycardia, Haematemesis, Nausea, Oxygen Saturation Decreased, Respiratory Disorder, Resuscitation
Patient was taking Defibrotide (View Usage). Patient had the following side effects: blood pressure decreased, bradycardia, haematemesis, nausea (What is nausea?), oxygen saturation decreased, respiratory disorder, resuscitation on Mar 27, 2006 from UNITED STATES Additional patient health information: Female patient , weighting 35.27 lb, was diagnosed with bone marrow transplant (What is bone marrow transplant?), venoocclusive liver disease and. Defibrotide dosage: 40mg/kg Iv/q6hrs Q6hrs Iv.

4834179-4 | Hypertension, Myocardial Infarction, Tachycardia
Adverse event was reported on Nov 18, 2005 by a Male patient taking Defibrotide (View Usage) (Dosage: 800 Mg Q 6 Hrs) was diagnosed with venoocclusive disease and. Location: UNITED STATES , 41 years of age, weighting 264.6 lb, After Defibrotide was administered, patient had the following side effects: hypertension, myocardial infarction, tachycardia. During the same period patient was treated with HYDROMORPHONE (View Hydromorphone Review and Hydromorphone Label ), BENADRYL (View Benadryl Review and Benadryl Label ), DIPHENHYDRAMINE HCL (View Diphenhydramine Hcl Review and Diphenhydramine Hcl Label ), TRIAMCINOLONE (View Triamcinolone Review and Triamcinolone Label ), DRY SKIN BATH OIL (View Dry Skin Bath Oil Review and Dry Skin Bath Oil Label ), DILAUDID (View Dilaudid Review and Dilaudid Label ), INSULIN REG HUMULIN (View Insulin -reg Humulin Review and Insulin -reg Humulin Label ), CHLORHEXIDINE (View Chlorhexidine Review and Chlorhexidine Label ).

4739433-2 | Hypotension, Pulmonary Oedema, Renal Failure, Tachypnoea
on Aug 08, 2005 Female patient from UNITED STATES , weighting 200.4 lb, was diagnosed with venoocclusive liver disease and was treated with Defibrotide (View Usage). Patient experienced the following unwanted or unexpected effects: hypotension, pulmonary oedema, renal failure, tachypnoea. Defibrotide dosage: 60 Mg/kg Q24hours Intravenous. During the same period patient was treated with SOLU MEDROL (View Solu-medrol Review and Solu-medrol Label ), PROGRAF (View Prograf Review and Prograf Label ), MYCOPHENOLATE (View Mycophenolate Review and Mycophenolate Label ), LACTULOSE (View Lactulose Review and Lactulose Label ), CASPOFUNGIN (View Caspofungin Review and Caspofungin Label ), ACYCLOVIR (View Acyclovir Review and Acyclovir Label ).


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To find out about documented side effects or safety concerns read either the drug label or the drug's package insert. You may also want to speak with your pharmacist or healthcare provider. All medicines have benefits and risks. The risks are the chances that something unwanted or unexpected could happen to you when you use them. You can protect yourself by searching summaries of recent safety alerts, adverse reports. Sometimes there are risks that only come to light after a medical product gets on the market and is used in a larger number of patients, for a longer period of time, and in patients whose health characteristics are different from those of the patients studied before approval.

Be aware of the following potential Defibrotide risks to be aware of: 1. Watch for any Serious adverse events, such as life-threatening situation, which can require an admission to hospital or longer-than-expected hospital stay, permanent disability, birth defect, miscarriage, stillbirth, or birth with serious disease requires medical care to prevent permanent damage
2. Any potential Defibrotide quality problem: suspected counterfeit product, potentially contaminated product indicated by suspicious odor or unusual color, inaccurate or unreadable product labeling
3. Potential Defibrotide use error: mixing up products with similar drug names or packaging, taking wrong dose of a drug because of confusing dosing instructions on label
4. When applicable, Problems with different manufacturer of same medicine: not getting same results from a generic drug as a brand name drug, or from another generic

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During the same period patient was treated with BUSULFAN, CYCLOPHOSPHAMIDE, CYTARABINE, METHYLPREDNISOLONE, CAPTOPRIL, CASPOFUNGIN, CYCLOSPORINE, DEFIBROTIDE.

defibrotide Episodes: 1: Diagnosed with major depression.Side effects: cardiac failure, myocarditis More: depakote Episodes: 2: Diagnosed with major depression ...

defibrotide Episodes: 1: Diagnosed with venoocclusive disease.Side effects: hypertension, myocardial infarction, tachycardia More: definity Episodes: 1

defibrotide Episodes: 1: Diagnosed with major depression.Side effects: cardiac failure, myocarditis More: definity Episodes: 8: Diagnosed with major depression ...

defibrotide Episodes: 1: Diagnosed with major depression.Side effects: cardiac failure, myocarditis More: demerol Episodes: 1: Diagnosed with major depression.Side ...

defibrotide Episodes: 1: Diagnosed with major depression.Side effects: cardiac failure, myocarditis More: definity Episodes: 3: Diagnosed with major depression ...

defibrotide Episodes: 1: Diagnosed with major depression.Side effects: cardiac failure, myocarditis More: demerol Episodes: 1: Diagnosed with major depression.Side ...

defibrotide Episodes: 1: Diagnosed with major depression.Side effects: cardiac failure, myocarditis More: depakote Episodes: 2: Diagnosed with major depression ...

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Defibrotide Reactions
Blood Pressure Decreased
Bradycardia
DialysisWhat is Dialysis?
Haematemesis
Hypertension
Hypotension
Myocardial Infarction
NauseaWhat is Nausea?
Oxygen Saturation Decreased
Pulmonary Oedema
Renal Failure
Renal Failure Acute
Respiratory Disorder
Resuscitation
Tachycardia
Tachypnoea
Defibrotide Side Effects Notice - The material on this site is for informational purposes only, and is not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. PatientsVille.com does not provide medical advice, diagnosis or treatment. The information regarding Defibrotide adverse reports, reviews and polls contained on PatientsVille.com site has not been scientifically or otherwise verified as to a cause and effect relationship and cannot be used to estimate the incidence of adverse drug reactions or for establishing or changing of patient treatments. Thank you for visiting Patientsville.com!