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Disulfiram adverse events reported to FDA.

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Summary

FDA Adverse Reports: 23. View All

Disulfiram FDA safety alerts: No

Reported deaths: 6

Reported hospitalizations: 11

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Often additional risks of using a medication, such as Disulfiram, become known after product is used by a larger number of patients, for a longer period of time, and by patients with different health characteristics from those studied before drug approval. This page allows You to Find answers and discuss health symptoms with other Disulfiram users, Learn more about unwanted side effects & find ways to reduce them. Browse Disulfiram Adverse Reports reported to FDA and participate in Disulfiram discussion, find alternative treatments and find ways to avoid or reduce risks associated with using Disulfiram. You can also Post a question to users community or Ask a Doctor. PatientsVille.com is Your Complete Guide to all common, undocumented and undisclosed side effects associated with drugs and vaccines. Browse More Drug Reports Here: A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

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Disulfiram Adverse Effect Reports (FDA)

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6887121-9 | Blood Creatine Phosphokinase Increased, Blood Creatine Phosphokinase Mb Increased, Electrocardiogram St Segment Depression, Hypotension, Loss Of Consciousness, Myocardial Ischaemia, Shock, Tonic Convulsion
on Jul 15, 2010 Male patient from JAPAN , 50 years of age, was treated with Disulfiram (View Usage). Patient experienced the following unwanted or unexpected effects: blood creatine phosphokinase increased, blood creatine phosphokinase mb increased, electrocardiogram st segment depression, hypotension, loss of consciousness, myocardial ischaemia, shock, tonic convulsion. Disulfiram dosage: Unk. During the same period patient was treated with ETHANOL (Unk) (View Ethanol Review and Ethanol Label ). Patient was hospitalized.

6846950-8 | Electrocardiogram St Segment Depression, Hypotension, Myocardial Ischaemia
Patient was taking Disulfiram (View Usage). Patient had the following side effects: electrocardiogram st segment depression, hypotension, myocardial ischaemia on Jun 29, 2010 from JAPAN Additional patient health information: Male patient , 50 years of age, . Disulfiram dosage: .

6608996-4 | Coagulopathy, Diarrhoea, Jaundice, Malaise, Mental Status Changes, Nausea
Adverse event was reported on Feb 26, 2010 by a Male patient taking Disulfiram (View Usage) (Dosage: Oral 047) was diagnosed with alcohol abuse and. Location: UNITED STATES , 62 years of age, weighting 138.9 lb, After Disulfiram was administered, patient had the following side effects: coagulopathy, diarrhoea, jaundice (What is jaundice?), malaise, mental status changes, nausea (What is nausea?). Patient was hospitalized.

6602295-2 | Coma, Convulsion, Intentional Overdose
on Feb 17, 2010 Male patient from BELGIUM , 35 years of age, was diagnosed with alcoholism (What is alcoholism?), suicide attempt and was treated with Disulfiram (View Usage). Patient experienced the following unwanted or unexpected effects: coma, convulsion, intentional overdose. Disulfiram dosage: 20 G, Single. Patient was hospitalized.


6583403-9 | Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased
on Feb 12, 2010 Male patient from UNITED STATES , 46 years of age, weighting 213.0 lb, was diagnosed with alcohol abuse and was treated with Disulfiram (View Usage). Patient had the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased. Disulfiram dosage: 250 Mg Pm Po.

6390446-7 | Alanine Aminotransferase Increased, Hepatic Enzyme Increased
Patient was taking Disulfiram (View Usage). After Disulfiram was administered, patient had the following side effects: alanine aminotransferase increased, hepatic enzyme increased on Oct 05, 2009 from UNITED STATES Additional patient health information: Male patient , 52 years of age, was diagnosed with alcoholism (What is alcoholism?) and. Disulfiram dosage: 250 Mg Every Day Po.

6332261-6 | Hepatic Enzyme Increased
Adverse event was reported on Aug 27, 2009 by a Male patient taking Disulfiram (View Usage) (Dosage: 250 Mg Every Day Po) was diagnosed with alcohol abuse and. Location: UNITED STATES , 47 years of age, weighting 192.0 lb, Patient experienced the following unwanted or unexpected effects: hepatic enzyme increased. Patient was hospitalized.

6303857-2 | Alanine Aminotransferase Increased
on Aug 07, 2009 Male patient from UNITED STATES , 52 years of age, was diagnosed with alcohol detoxification and was treated with Disulfiram (View Usage). Patient had the following side effects: alanine aminotransferase increased. Disulfiram dosage: 250 Mg Every Day Po.

6228023-0 | Malignant Neoplasm Progression, Transient Ischaemic Attack
on Jun 10, 2009 Female patient from UNITED STATES , weighting 114.9 lb, was diagnosed with non-small cell lung cancer and was treated with Disulfiram (View Usage). After Disulfiram was administered, patient had the following side effects: malignant neoplasm progression, transient ischaemic attack. Disulfiram dosage: 250 Mg Qd Po. During the same period patient was treated with COPPER GLUCONATE, 2MG, TWINLAB, IND #100,937 (2 Mg Qd Po) (View Copper Gluconate, 2mg, Twinlab, Ind #100,937 Review and Copper Gluconate, 2mg, Twinlab, Ind #100,937 Label ).

6099408-0 | Acute Hepatic Failure, No Therapeutic Response
Patient was taking Disulfiram (View Usage). Patient experienced the following unwanted or unexpected effects: acute hepatic failure, no therapeutic response on Feb 26, 2009 from UNITED STATES Additional patient health information: Male patient , 51 years of age, weighting 190.0 lb, was diagnosed with alcoholism (What is alcoholism?) and. Disulfiram dosage: 125 Mg Pm Po. Patient was hospitalized.

6028662-6 | Alcohol Use, Flushing, Hypotension, Nausea, Tachycardia, Treatment Noncompliance
Adverse event was reported on Jan 05, 2009 by a Male patient taking Disulfiram (View Usage) (Dosage: 500 Mg Hs Po) was diagnosed with alcoholism (What is alcoholism?) and. Location: UNITED STATES , 46 years of age, Patient had the following side effects: alcohol use, flushing, hypotension, nausea (What is nausea?), tachycardia, treatment noncompliance. Patient was hospitalized.

6020715-1 | Aversion, Stereotypy
on Dec 10, 2008 Female patient from TAIWAN, PROVINCE OF CHINA , 39 years of age, was treated with Disulfiram (View Usage). After Disulfiram was administered, patient had the following side effects: aversion, stereotypy. Disulfiram dosage: (200 Mg Qd, At Bedtime). During the same period patient was treated with ESCITALOPRAM (View Escitalopram Review and Escitalopram Label ).

5682449-2 | Acute Hepatic Failure
on Mar 26, 2008 Female patient from UNITED STATES , 32 years of age, weighting 108.0 lb, was diagnosed with alcoholism (What is alcoholism?) and was treated with Disulfiram (View Usage). Patient experienced the following unwanted or unexpected effects: acute hepatic failure. Disulfiram dosage: . Patient was hospitalized.

5630266-1 | Cardio-respiratory Arrest
Patient was taking Disulfiram (View Usage). Patient had the following side effects: cardio-respiratory arrest on Feb 04, 2008 from UNITED STATES Additional patient health information: Male patient , 33 years of age, . Disulfiram dosage: . During the same period patient was treated with ETHANOL(ETHANOL) (View Ethanol(ethanol) Review and Ethanol(ethanol) Label ).

5625297-1 | Cardio-respiratory Arrest
Adverse event was reported on Feb 04, 2008 by a Female patient taking Disulfiram (View Usage) (Dosage: ) . Location: UNITED STATES , 21 years of age, After Disulfiram was administered, patient had the following side effects: cardio-respiratory arrest. During the same period patient was treated with METHANOL(METHANOL) (View Methanol(methanol) Review and Methanol(methanol) Label ), LITHIUM CARBONATE (View Lithium Carbonate Review and Lithium Carbonate Label ).

5613692-6 | Alcohol Use, Cardiac Arrest, Completed Suicide, Respiratory Arrest
on Jan 07, 2008 Male patient from UNITED STATES , 33 years of age, was treated with Disulfiram (View Usage). Patient experienced the following unwanted or unexpected effects: alcohol use, cardiac arrest (What is cardiac arrest?), completed suicide, respiratory arrest. Disulfiram dosage: (df Oral). During the same period patient was treated with ETHANOL ((beverage Oral)) (View Ethanol Review and Ethanol Label ).

5613687-2 | Cardiac Arrest, Completed Suicide, Poisoning, Respiratory Arrest
on Jan 07, 2008 Female patient from UNITED STATES , 21 years of age, was treated with Disulfiram (View Usage). Patient had the following side effects: cardiac arrest (What is cardiac arrest?), completed suicide, poisoning (What is poisoning?), respiratory arrest. Disulfiram dosage: (df Oral). During the same period patient was treated with METHANOL ((df Oral)) (View Methanol Review and Methanol Label ), LITHIUM CARBONATE ((df Oral)) (View Lithium Carbonate Review and Lithium Carbonate Label ).

5572935-8 | Condition Aggravated, Psychotic Disorder
Patient was taking Disulfiram (View Usage). After Disulfiram was administered, patient had the following side effects: condition aggravated, psychotic disorder (What is psychotic disorder?) on Dec 19, 2007 from UNITED STATES Additional patient health information: Male patient , 24 years of age, weighting 180.0 lb, . Disulfiram dosage: 500mg Po. During the same period patient was treated with FENOFIBRATE (View Fenofibrate Review and Fenofibrate Label ), LITHIUM (View Lithium Review and Lithium Label ), NAVANE (View Navane Review and Navane Label ), LOVASTATIN (View Lovastatin Review and Lovastatin Label ), NIASPAN (View Niaspan Review and Niaspan Label ), METOPROLOL (View Metoprolol Review and Metoprolol Label ), LORAZEPAM (View Lorazepam Review and Lorazepam Label ). Patient was hospitalized.

5318900-7 | Wernicke's Encephalopathy
Adverse event was reported on Apr 27, 2007 by a Male patient taking Disulfiram (View Usage) (Dosage: 500 Mg, Daily, Unk) was diagnosed with alcoholism (What is alcoholism?) and. Location: BELGIUM , 41 years of age, Patient experienced the following unwanted or unexpected effects: wernicke's encephalopathy. Patient was hospitalized.

5288154-9 | Acute Myocardial Infarction, Alcohol Interaction, Food Interaction
on Mar 19, 2007 Male patient from TURKEY , 36 years of age, was diagnosed with alcoholism (What is alcoholism?) and was treated with Disulfiram (View Usage). Patient had the following side effects: acute myocardial infarction, alcohol interaction, food interaction. Disulfiram dosage: 0.5 G, Daily, Oral. During the same period patient was treated with ALCOHOL (FROM FERMENTED VINEGAR) (ETHANOL) (Oral) (View Alcohol (from Fermented Vinegar) (ethanol) Review and Alcohol (from Fermented Vinegar) (ethanol) Label ). Patient was hospitalized.

5238493-2 | Cardio-respiratory Arrest
on Feb 01, 2007 Female patient from UNITED STATES , 38 years of age, was treated with Disulfiram (View Usage). After Disulfiram was administered, patient had the following side effects: cardio-respiratory arrest. Disulfiram dosage: . During the same period patient was treated with DILACOR XR (View Dilacor Xr Review and Dilacor Xr Label ).

5147236-2 | Cardiac Arrest, Completed Suicide, Respiratory Arrest
Patient was taking Disulfiram (View Usage). Patient experienced the following unwanted or unexpected effects: cardiac arrest (What is cardiac arrest?), completed suicide, respiratory arrest on Oct 24, 2006 from UNITED STATES Additional patient health information: Female patient , 38 years of age, . Disulfiram dosage: Df Po. During the same period patient was treated with DILTIAZEM HCL (Df Po) (View Diltiazem Hcl Review and Diltiazem Hcl Label ).

5144684-1 | Agitation, Alcohol Use, Alcoholism, Anxiety, Cerebral Disorder, Communication Disorder, Confusional State, Decreased Appetite, Delirium
Adverse event was reported on Oct 19, 2006 by a Female patient taking Disulfiram (View Usage) (Dosage: 250 Mg/day) was diagnosed with alcoholism (What is alcoholism?) and. Location: UNITED STATES , 51 years of age, Patient had the following side effects: agitation, alcohol use, alcoholism (What is alcoholism?), anxiety (What is anxiety?), cerebral disorder, communication disorder, confusional state, decreased appetite, delirium. Patient was hospitalized.


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Disulfiram Questions, Answers, Feedback and Comments

Comments to date: 1. Page 1 of 1.

prathi   CHENNAI

4:12am on Monday, February 15th, 2010

My relative is drinking a lot, totally he is becoming unconsious, He is behaving such a bad manor wi... read more »

To find out about documented side effects or safety concerns read either the drug label or the drug's package insert. You may also want to speak with your pharmacist or healthcare provider. All medicines have benefits and risks. The risks are the chances that something unwanted or unexpected could happen to you when you use them. You can protect yourself by searching summaries of recent safety alerts, adverse reports. Sometimes there are risks that only come to light after a medical product gets on the market and is used in a larger number of patients, for a longer period of time, and in patients whose health characteristics are different from those of the patients studied before approval.

Be aware of the following potential Disulfiram risks to be aware of: 1. Watch for any Serious adverse events, such as life-threatening situation, which can require an admission to hospital or longer-than-expected hospital stay, permanent disability, birth defect, miscarriage, stillbirth, or birth with serious disease requires medical care to prevent permanent damage
2. Any potential Disulfiram quality problem: suspected counterfeit product, potentially contaminated product indicated by suspicious odor or unusual color, inaccurate or unreadable product labeling
3. Potential Disulfiram use error: mixing up products with similar drug names or packaging, taking wrong dose of a drug because of confusing dosing instructions on label
4. When applicable, Problems with different manufacturer of same medicine: not getting same results from a generic drug as a brand name drug, or from another generic

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Disulfiram Reactions
Acute Hepatic Failure
Acute Myocardial Infarction
Agitation
Alanine Aminotransferase Increased
Alcohol Interaction
Alcohol Use
AlcoholismWhat is Alcoholism?
AnxietyWhat is Anxiety?
Aspartate Aminotransferase Increased
Aversion
Blood Creatine Phosphokinase Increased
Blood Creatine Phosphokinase Mb Increased
Cardiac ArrestWhat is Cardiac arrest?
Cardio-respiratory Arrest
Cerebral Disorder
Coagulopathy
Coma
Communication Disorder
Completed Suicide
Condition Aggravated
Confusional State
Convulsion
Decreased Appetite
Delirium
Electrocardiogram St Segment Depression
Hepatic Enzyme Increased
Hypotension
Myocardial Ischaemia
NauseaWhat is Nausea?
Respiratory Arrest
Disulfiram Side Effects Notice - The material on this site is for informational purposes only, and is not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. PatientsVille.com does not provide medical advice, diagnosis or treatment. The information regarding Disulfiram adverse reports, reviews and polls contained on PatientsVille.com site has not been scientifically or otherwise verified as to a cause and effect relationship and cannot be used to estimate the incidence of adverse drug reactions or for establishing or changing of patient treatments. Thank you for visiting Patientsville.com!