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From simple mix-ups to fatal overdoses, medication mistakes happen, on average, once a day to every hospital patient, a new report says. Nationwide, at least 1.5 million people annually are harmed from drug errors, more than half of them in nursing homes.
Many Unfavorable Drug Studies Aren’t Published. Nearly a third of antidepressant drug studies are never published in the medical literature, and nearly all of those happen to show that the drug being tests failed to work.
Only Drugs That are Safe Should be put on the Market. Drug developers are just beginning to come to grips with recent FDA oversight reforms and how they will affect drug safety. But, it appears that industry and consumer advocates are not together on how well the overhaul will be able to prevent future drug safety scandals.

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Review Divalproex Safety Reports submitted to FDA

Total Divalproex reports: 23.
Divalproex FDA safety alerts: 2002 .
Reported deaths: 1    Reported hospitalizations: 9.
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FDA Reported Divalproex Side Effects: hyperammonaemia, pancreatitis acute, lethargy, disorientation, depressed level of consciousness, mental status changes, loss of consciousness, hyponatraemia, fall, sedation, dizziness.
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Divalproex Side Effects Report #5611244-5
Consumer or non-health professional from FRANCE reported DIVALPROEX problem on Jan 23, 2008. Female patient, 44 years of age, was diagnosed with bipolar disorder, agitation, hostility and was treated with DIVALPROEX. After drug was administered, patient experienced the following problems/side effects: delusion, hyperprolactinaemia, somatic delusion, weight increased. DIVALPROEX dosage: unknown. During the same period patient was treated with DIAZEPAM, HALOPERIDOL. Patient recovered.

Divalproex Side Effects Report #5622631-3
DIVALPROEX problem was reported by a Pharmacist from UNITED STATES on Feb 11, 2008. Male patient, 58 years of age, was treated with DIVALPROEX. After drug was administered, patient experienced the following problems/side effects: confusional state, mental status changes. DIVALPROEX dosage: 1500MG HS PO. During the same period patient was treated with ALPRAZOLAM. Patient was hospitalized. Patient recovered.

Divalproex Side Effects Report #5625186-2
Consumer or non-health professional from FRANCE reported DIVALPROEX problem on Jan 31, 2008. Female patient, 33 years of age, was treated with DIVALPROEX. After drug was administered, patient experienced the following problems/side effects: hyperammonaemia. DIVALPROEX dosage: unknown. During the same period patient was treated with CLONAZEPAM, VENLAFAXINE EXTENDED, MIRTAZAPINE, BUPROPION, HYDROXYZINE. Patient was hospitalized. Patient recovered.

Divalproex Side Effects Report #5636761-3
DIVALPROEX problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 19, 2008. Male patient, 46 years of age, was treated with DIVALPROEX. After drug was administered, patient experienced the following problems/side effects: fluid retention. DIVALPROEX dosage: 1500MG PM PO. Patient recovered.

Divalproex Side Effects Report #5592316-0
Pharmacist from CANADA reported DIVALPROEX problem on Dec 31, 2007. Female patient, 37 years of age, was diagnosed with mental disorder and was treated with DIVALPROEX. After drug was administered, patient experienced the following problems/side effects: agitation, anhedonia, anxiety, bipolar i disorder, crying, decreased appetite, energy increased, feeling abnormal. DIVALPROEX dosage: 1000 MG;PM. During the same period patient was treated with SERTRALINE, ZOPICLONE, RISPERIDONE, QUETIAPINE FUMARATE. Patient was hospitalized. Patient recovered.

Divalproex Side Effects Report #5593105-3
DIVALPROEX problem was reported by a Consumer or non-health professional from UNITED STATES on Jan 14, 2008. Male patient, 80 years of age, weighting 207.0 lb, was diagnosed with convulsion and was treated with DIVALPROEX. After drug was administered, patient experienced the following problems/side effects: confusional state, disorientation, lethargy, mental status changes, somnolence. DIVALPROEX dosage: 500MG EVERY DAY PO. During the same period patient was treated with QUETIAPINE FUMARATE. Patient was hospitalized. Patient recovered.

Divalproex Side Effects Report #5601334-5
Consumer or non-health professional from UNITED STATES reported DIVALPROEX problem on Jan 22, 2008. Male patient, 80 years of age, weighting 207.0 lb, was diagnosed with convulsion and was treated with DIVALPROEX. After drug was administered, patient experienced the following problems/side effects: confusional state, disorientation, lethargy, mental status changes, somnolence. DIVALPROEX dosage: 500MG EVERY DAY PO. During the same period patient was treated with QUETIAPINE. Patient was hospitalized. Patient recovered.

Divalproex Side Effects Report #5602871-X
DIVALPROEX problem was reported by a Consumer or non-health professional from UNITED STATES on Jan 16, 2008. Male patient, 49 years of age, was treated with DIVALPROEX. After drug was administered, patient experienced the following problems/side effects: overdose. DIVALPROEX dosage: unknown. During the same period patient was treated with IBUPROFEN, LEVOTHYROXINE. Patient was hospitalized. Patient died.

Divalproex Side Effects Report #5566647-4
Pharmacist from UNITED STATES reported DIVALPROEX problem on Dec 18, 2007. Male patient, 70 years of age, weighting 150.0 lb, was treated with DIVALPROEX. After drug was administered, patient experienced the following problems/side effects: liver function test abnormal. DIVALPROEX dosage: 1000MG PO. During the same period patient was treated with QUETIAPINE, DONEPEZIL, SEROQUEL, NAMENDA, MIRALAX, DEPAKOTE, DIPHENHYDRAMINE, TRAZODONE. Patient recovered.

Divalproex Side Effects Report #5567001-1
DIVALPROEX problem was reported by a Pharmacist from UNITED STATES on Dec 18, 2007. Female patient, 60 years of age, weighting 138.0 lb, was treated with DIVALPROEX. After drug was administered, patient experienced the following problems/side effects: platelet count decreased. DIVALPROEX dosage: 500MG TID PO. During the same period patient was treated with ZYDIS, ACETAMINOPHEN PRN. Patient recovered.

Divalproex Side Effects Report #5567008-4
Pharmacist from UNITED STATES reported DIVALPROEX problem on Dec 18, 2007. Male patient, 16 years of age, weighting 120.0 lb, was treated with DIVALPROEX. After drug was administered, patient experienced the following problems/side effects: platelet count decreased. DIVALPROEX dosage: unknown. During the same period patient was treated with GEODON, ACETAMINOPHEN, FIBERCON. Patient recovered.

Divalproex Side Effects Report #5567019-9
DIVALPROEX problem was reported by a Pharmacist from UNITED STATES on Dec 18, 2007. Male patient, 41 years of age, weighting 177.0 lb, was treated with DIVALPROEX. After drug was administered, patient experienced the following problems/side effects: dermatitis acneiform, scratch. DIVALPROEX dosage: 500MG BID PO. During the same period patient was treated with METHADONE, TESTOSTERONE TD, NICOTINE, COMBIVENT, FIBERCON, HYDROXYZINE, CITALOPRAM HYDROBROMIDE, QUETIAPINE. Patient recovered.

Divalproex Side Effects Report #5570372-3
Pharmacist from UNITED STATES reported DIVALPROEX problem on Dec 19, 2007. Female patient, 43 years of age, weighting 200.0 lb, was treated with DIVALPROEX. After drug was administered, patient experienced the following problems/side effects: platelet count decreased. DIVALPROEX dosage: 1500MG DAY PO. During the same period patient was treated with GEODON, QUETIAPINE, METRONIDAZOLE, IBUPROFEN, PSEUDOEPHEDRINE. Patient recovered.

Divalproex Side Effects Report #5572934-6
DIVALPROEX problem was reported by a Pharmacist from UNITED STATES on Dec 19, 2007. Male patient, 37 years of age, weighting 292.0 lb, was treated with DIVALPROEX. After drug was administered, patient experienced the following problems/side effects: weight increased. DIVALPROEX dosage: 1000MG PO. During the same period patient was treated with ZIPRASIDONE, LORATADINE, ZOLPIDEM. Patient recovered.

Divalproex Side Effects Report #5518920-3
Pharmacist from UNITED STATES reported DIVALPROEX problem on Nov 14, 2007. Female patient, 22 years of age, weighting 136.0 lb, was diagnosed with bipolar disorder and was treated with DIVALPROEX. After drug was administered, patient experienced the following problems/side effects: stevens-johnson syndrome. DIVALPROEX dosage: 1000MG DAILY PO. During the same period patient was treated with SEROQUEL, IMITREX, NEURONTIN. Patient recovered.

Divalproex Side Effects Report #5519209-9
DIVALPROEX problem was reported by a Pharmacist from UNITED STATES on Nov 14, 2007. Male patient, 47 years of age, weighting 195.0 lb, was treated with DIVALPROEX. After drug was administered, patient experienced the following problems/side effects: thrombocytopenia. DIVALPROEX dosage: 1500 MG/DAY PO. Patient recovered.

Divalproex Side Effects Report #5526268-6
Pharmacist from UNITED STATES reported DIVALPROEX problem on Nov 21, 2007. Male patient, 76 years of age, weighting 203.0 lb, was diagnosed with bipolar i disorder and was treated with DIVALPROEX. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, hyperammonaemia, lethargy, mental status changes, speech disorder. DIVALPROEX dosage: 3000MG EVERY DAY PO. During the same period patient was treated with LISINOPRIL AND HYDROCHLOROTHIAZIDE, METOPROLOL, PRIMIDONE. Patient was hospitalized. Patient recovered.

Divalproex Side Effects Report #5526375-8
DIVALPROEX problem was reported by a Pharmacist from UNITED STATES on Nov 21, 2007. Male patient, 56 years of age, was diagnosed with bipolar i disorder and was treated with DIVALPROEX. After drug was administered, patient experienced the following problems/side effects: ammonia increased, confusional state. DIVALPROEX dosage: 1000MG PM PO. Patient was hospitalized. Patient recovered.

Divalproex Side Effects Report #5499809-5
Consumer or non-health professional from FRANCE reported DIVALPROEX problem on Oct 18, 2007. Male patient, 36 years of age, was diagnosed with mood swings and was treated with DIVALPROEX. After drug was administered, patient experienced the following problems/side effects: angina pectoris, anorexia, feeling abnormal, haematochezia, hyperhidrosis, insomnia, intentional self-injury, mood altered, muscle twitching. DIVALPROEX dosage: unknown. Patient recovered.

Divalproex Side Effects Report #5466716-3
DIVALPROEX problem was reported by a Pharmacist from UNITED STATES on Sept 24, 2007. Male patient, 13 years of age, was diagnosed with aggression and was treated with DIVALPROEX. After drug was administered, patient experienced the following problems/side effects: dizziness. DIVALPROEX dosage: 500 MG PO. Patient recovered.

Divalproex Side Effects Report #5412242-7
Pharmacist from UNITED STATES reported DIVALPROEX problem on Aug 10, 2007. Male patient, 86 years of age, was diagnosed with bipolar i disorder and was treated with DIVALPROEX. After drug was administered, patient experienced the following problems/side effects: agitation, delirium, disorientation, fall, hyperammonaemia. DIVALPROEX dosage: 2000MG HS PO. During the same period patient was treated with ZOLOFT, PLAVIX, GABAPENTIN, MIRTAZAPINE, ISOSORBIDE ER, MAGNESIUM OXIDE, KLONOPIN, COLACE. Patient was hospitalized. Patient recovered.

Divalproex Side Effects Report #5419475-4
DIVALPROEX problem was reported by a Pharmacist from UNITED STATES on Aug 17, 2007. Male patient, weighting 146.0 lb, was diagnosed with affective disorder and was treated with DIVALPROEX. After drug was administered, patient experienced the following problems/side effects: faecaloma, ileus, pancreatitis acute. DIVALPROEX dosage: 1000MG BID PO, 1250MG BID PO. During the same period patient was treated with DIVALPROEX EXTENDED RELEASE, ENALAPRIL MALEATE, FENOFIBRATE, LEVOTHYROXINE, ROSIGLITAZONE, THIOTHIXENE, ATORVASTATIN CALCIUM. Patient recovered.

Divalproex Side Effects Report #5420920-9
Pharmacist from UNITED STATES reported DIVALPROEX problem on Aug 17, 2007. Female patient, weighting 157.3 lb, was diagnosed with schizophrenia, paranoid type and was treated with DIVALPROEX. After drug was administered, patient experienced the following problems/side effects: fatigue, lethargy. DIVALPROEX dosage: 1500 MG. Patient recovered.


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delusion, hyperprolactinaemia, somatic delusion, weight increased, confusional state, mental status changes, , was diagnosed with bipolar disorder, agitation, hostility and was diagnosed with mental disorder and