Duloxetine Safety Questions, Duloxetine Answers
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Duloxetine Safety Reports
Total Duloxetine reports: 144.Duloxetine FDA safety alerts: 2005 .
Reported deaths: 17 Reported hospitalizations: 71.
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Reported Duloxetine Side Effects: nausea, dizziness, suicide attempt, alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, convulsion, loss of consciousness, syncope, akathisia, tremor.
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Showing 1-50 of 144 Next >
Duloxetine Side Effects Report #5364000-XPhysician from GREECE reported DULOXETINE problem on June 12, 2007. Female patient, 17 years of age, was diagnosed with panic disorder and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: aggression, anxiety, cyclothymic disorder, irritability. DULOXETINE dosage: 120 MG, DAILY (1/D). During the same period patient was treated with DULOXETINE HYDROCHLORIDE. Patient recovered.
Duloxetine Side Effects Report #5364010-2
DULOXETINE problem was reported by a Physician from AUSTRIA on June 12, 2007. Male patient, 91 years of age, weighting 154.3 lb, was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: cardiac failure. DULOXETINE dosage: 60 MG, DAILY (1/D). During the same period patient was treated with INSULINE. Patient died on 03/01/2007.
Duloxetine Side Effects Report #5367860-1
Physician from AUSTRIA reported DULOXETINE problem on June 18, 2007. Male patient, 91 years of age, weighting 154.3 lb, was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: cardiac failure. DULOXETINE dosage: 60 MG, DAILY (1/D). During the same period patient was treated with INSULINE. Patient died on 03/01/2007.
Duloxetine Side Effects Report #5367876-5
DULOXETINE problem was reported by a Physician from ITALY on June 15, 2007. Male patient, 52 years of age, was diagnosed with depression, pain and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: hypotension, syncope. DULOXETINE dosage: 60 MG, DAILY (1/D). During the same period patient was treated with OXYCODONE HYDROCHLORIDE W. Patient recovered.
Duloxetine Side Effects Report #5368809-8
Physician from AUSTRIA reported DULOXETINE problem on June 18, 2007. Male patient, 91 years of age, weighting 154.3 lb, was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: cardiac failure. DULOXETINE dosage: 60 MG, DAILY (1/D). During the same period patient was treated with INSULINE. Patient died on 03/01/2007.
Duloxetine Side Effects Report #5368825-6
DULOXETINE problem was reported by a Physician from ITALY on June 15, 2007. Male patient, 52 years of age, was diagnosed with depression, pain and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: hypotension, syncope. DULOXETINE dosage: 60 MG, DAILY (1/D). During the same period patient was treated with OXYCODONE HYDROCHLORIDE W. Patient recovered.
Duloxetine Side Effects Report #5372345-2
Physician from JAPAN reported DULOXETINE problem on June 14, 2007. Male patient, 62 years of age, weighting 176.4 lb, was diagnosed with diabetic neuropathy, thrombosis prophylaxis, diabetes mellitus non-insulin-dependent and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: iiird nerve disorder. DULOXETINE dosage: 20 MG, DAILY (1/D). During the same period patient was treated with DULOXETINE HYDROCHLORIDE, DULOXETINE HYDROCHLORIDE, CYANOCOBALAMIN, ASPIRIN, HUMALOG, INNOLET N. Patient was hospitalized. Patient recovered.
Duloxetine Side Effects Report #5372490-1
DULOXETINE problem was reported by a Physician from JAPAN on June 20, 2007. Male patient, 63 years of age, weighting 176.4 lb, was diagnosed with diabetic neuropathy, thrombosis prophylaxis, diabetes mellitus non-insulin-dependent and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: iiird nerve paralysis. DULOXETINE dosage: 20 MG, DAILY (1/D). During the same period patient was treated with DULOXETINE HYDROCHLORIDE, DULOXETINE HYDROCHLORIDE, DULOXETINE HYDROCHLORIDE, CYANOCOBALAMIN, ASPIRIN, HUMALOG, INNOLET N, HUMULIN. Patient was hospitalized. Patient recovered.
Duloxetine Side Effects Report #5373939-0
Consumer or non-health professional from DENMARK reported DULOXETINE problem on June 19, 2007. Female patient, 29 years of age, was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: dizziness, influenza like illness, loss of consciousness, nausea. DULOXETINE dosage: 30 MG, UNK. Patient recovered.
Duloxetine Side Effects Report #5048541-0
DULOXETINE problem was reported by a Physician from DOMINICAN REPUBLIC on June 12, 2006. Female patient was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: non-hodgkin's lymphoma. DULOXETINE dosage: 60 MG, DAILY (1/D), ORAL. Patient recovered.
Duloxetine Side Effects Report #5048563-X
Physician from HUNGARY reported DULOXETINE problem on June 15, 2006. Male patient, 67 years of age, was diagnosed with depression and was treated with DULOXETINE. DULOXETINE dosage: 60 MG, DAILY (1/D), ORAL. Patient died on 05/15/2006.
Duloxetine Side Effects Report #5048671-3
DULOXETINE problem was reported by a Consumer or non-health professional from UNITED STATES on June 14, 2006. Male patient, 80 years of age, was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: subarachnoid haemorrhage. DULOXETINE dosage: 60 MG, DAILY (1/D), ORAL. During the same period patient was treated with MOTENS, PLAVIX, CRESTOR, MOXON, GLICLAZIDE, PANTOPRAZOLE, EFEXOR. Patient was hospitalized. Patient recovered.
Duloxetine Side Effects Report #5052948-5
Health Professional from DENMARK reported DULOXETINE problem on June 19, 2006. Female patient, weighting 160.9 lb, was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: electrocardiogram qt prolonged. DULOXETINE dosage: 60 MG, ORAL. During the same period patient was treated with REMERON, NEXIUM, ALOPAM, STILNOCT. Patient recovered.
Duloxetine Side Effects Report #5059209-9
DULOXETINE problem was reported by a Physician from ARGENTINA on June 29, 2006. Female patient, 64 years of age, weighting 174.2 lb, was diagnosed with fibromyalgia and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: dysphagia, erythema, headache, hypersensitivity, nausea, pain, rash, skin lesion. DULOXETINE dosage: unknown. During the same period patient was treated with ACETAMINOPHEN. Patient was hospitalized. Patient recovered.
Duloxetine Side Effects Report #5059889-8
Consumer or non-health professional from DENMARK reported DULOXETINE problem on July 04, 2006. Male patient, 53 years of age, was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, overdose. DULOXETINE dosage: 180 MG, DAILY (1/D), ORAL. During the same period patient was treated with ORABET, LAMICTAL, REMERON. Patient recovered.
Duloxetine Side Effects Report #5060984-8
DULOXETINE problem was reported by a Pharmacist from UNITED STATES on July 20, 2006. Male patient was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: tremor. DULOXETINE dosage: 20 MG DAILY PO. During the same period patient was treated with LISINOPRIL, LORAZEPAM, OXYCODONE AND ACETAMINOPHEN, TERAZOSIN. Patient recovered.
Duloxetine Side Effects Report #5067724-7
Physician from HUNGARY reported DULOXETINE problem on July 10, 2006. Male patient, 67 years of age, weighting 205.0 lb, was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: injury asphyxiation. DULOXETINE dosage: 60 MG DAILY (1/D) ORAL. During the same period patient was treated with MIANSERIN, SUPRASTIN, ALFETIM, BISOPROLOL FUMARATE, MONOPRIL. Patient died.
Duloxetine Side Effects Report #5073171-4
DULOXETINE problem was reported by a Physician from DOMINICAN REPUBLIC on July 19, 2006. Female patient, 52 years of age, was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: non-hodgkin's lymphoma, tremor. DULOXETINE dosage: 60 MG DAILY (1/D) ORAL. Patient recovered.
Duloxetine Side Effects Report #5076322-0
Consumer or non-health professional from ITALY reported DULOXETINE problem on July 26, 2006. Female patient was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: gastritis, hypercholesterolaemia, hypertriglyceridaemia, transaminases increased. DULOXETINE dosage: 20 MG, DAILY (1/D), ORAL. During the same period patient was treated with ESCITALOPRAM, REMERON. Patient recovered.
Duloxetine Side Effects Report #5076910-1
DULOXETINE problem was reported by a Physician from UNITED STATES on July 26, 2006. Female patient, 31 years of age, was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: acute myocardial infarction, blood pressure increased, cardiac disorder, cardiomyopathy, clonus, confusional state, heart rate increased, muscle twitching, nystagmus. DULOXETINE dosage: unknown. During the same period patient was treated with PAROXETINE, BUPROPION, CLONAZEPAM. Patient was hospitalized. Patient recovered.
Duloxetine Side Effects Report #5078409-5
Physician from HUNGARY reported DULOXETINE problem on July 21, 2006. Male patient, 63 years of age, weighting 200.6 lb, was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: completed suicide, injury asphyxiation. DULOXETINE dosage: 60 MG, DAILY (1/D), ORAL. During the same period patient was treated with MIANSERIN, SUPRASTIN, ALFETIM, BISOPROLOL FUMARATE, MONOPRIL, ZOLPIDEM TARTRATE. Patient died.
Duloxetine Side Effects Report #5078410-1
DULOXETINE problem was reported by a Physician from DENMARK on July 24, 2006. Female patient, 61 years of age, weighting 160.9 lb, was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: electrocardiogram qt prolonged. DULOXETINE dosage: 60 MG, ORAL. During the same period patient was treated with REMERON, NEXIUM, ALOPRAM, STILNOCT. Patient recovered.
Duloxetine Side Effects Report #5084525-4
Physician from SPAIN reported DULOXETINE problem on July 25, 2006. Female patient, 43 years of age, was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: condition aggravated, diabetes mellitus, dry eye, dry mouth, dysstasia, food intolerance, nausea, prostration, visual acuity reduced. DULOXETINE dosage: 60 MG DAILY (1/D) ORAL. During the same period patient was treated with LANTUS, NOVOMIX, TARDYFERON. Patient recovered.
Duloxetine Side Effects Report #5088708-9
DULOXETINE problem was reported by a Physician from DENMARK on Aug 07, 2006. Female patient, 56 years of age, was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: skin haemorrhage. DULOXETINE dosage: 60 MG, ORAL. During the same period patient was treated with TAMOXIFEN CITRATE, ACETAMINOPHEN, PINEX, DOLOL. Patient was hospitalized. Patient recovered.
Duloxetine Side Effects Report #5097507-3
Physician from ITALY reported DULOXETINE problem on Aug 14, 2006. Female patient, 65 years of age, was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: epistaxis, hypertensive crisis. DULOXETINE dosage: 60 MG, DAILY (1/D), ORAL. During the same period patient was treated with ENAPREN. Patient was hospitalized. Patient recovered.
Duloxetine Side Effects Report #5097508-5
DULOXETINE problem was reported by a Physician from HUNGARY on Aug 14, 2006. Female patient, 50 years of age, was diagnosed with major depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: bradycardia, brain stem syndrome, cardiac disorder, computerised tomogram abnormal, condition aggravated, hypotonia, locked-in syndrome, miosis. DULOXETINE dosage: 30 MG, DAILY (1/D), ORAL. Patient was hospitalized. Patient died on 08/04/2006.
Duloxetine Side Effects Report #5102925-0
Health Professional from GERMANY reported DULOXETINE problem on Aug 22, 2006. Female patient, 66 years of age, was diagnosed with urinary incontinence and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, gamma-glutamyltransferase increased, hepatic enzyme increased, upper limb fracture. DULOXETINE dosage: 40 MG, UNK; ORAL. Patient was hospitalized. Patient recovered.
Duloxetine Side Effects Report #5104003-3
DULOXETINE problem was reported by a Health Professional from GREECE on Aug 23, 2006. Female patient, 50 years of age, weighting 132.3 lb, was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: depersonalisation, restlessness, suicide attempt. DULOXETINE dosage: 60 MG, 2/D, ORAL. During the same period patient was treated with SEROQUEL, TRANXENE. Patient recovered.
Duloxetine Side Effects Report #5105246-5
Physician from UNITED STATES reported DULOXETINE problem on Aug 14, 2006. Female patient, 30 years of age, was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: eosinophilic pneumonia acute, heart rate increased, lung consolidation, respiratory failure, shock. DULOXETINE dosage: unknown. During the same period patient was treated with FLUOXETINE, AZITHROMYCIN, CYANOCOBALAMIN, VITAMINS, GARLIC. Patient was hospitalized. Patient recovered.
Duloxetine Side Effects Report #5106623-9
DULOXETINE problem was reported by a Physician from HUNGARY on Aug 28, 2006. Female patient was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: biliary colic, cholelithiasis. DULOXETINE dosage: unknown. Patient was hospitalized. Patient recovered.
Duloxetine Side Effects Report #5117754-1
Consumer or non-health professional from BELGIUM reported DULOXETINE problem on Sept 05, 2006. Male patient, 80 years of age, was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: coma, fall, injury, loss of consciousness, subarachnoid haemorrhage, subdural haematoma. DULOXETINE dosage: 60 MG, DAILY (1/D), BUCCAL. During the same period patient was treated with MOTENS, PLAVIX, CRESTOR, MOXON, GLICLAZIDE, PANTOPRAZOLE, EFEXOR. Patient was hospitalized. Patient recovered.
Duloxetine Side Effects Report #5118193-X
DULOXETINE problem was reported by a Physician from BELGIUM on Sept 11, 2006. Male patient, 79 years of age, was diagnosed with depression and was treated with DULOXETINE. DULOXETINE dosage: 60 MG, DAILY (1/D), ORAL; 30 MG, ORAL. Patient died.
Duloxetine Side Effects Report #5118194-1
Pharmacist from GREECE reported DULOXETINE problem on Sept 08, 2006. Female patient, 75 years of age, was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: condition aggravated, depression, suicidal ideation. DULOXETINE dosage: 60 MG, DAILY (1/D), ORAL. During the same period patient was treated with ZOLOFT, ZYBAN. Patient was hospitalized. Patient recovered.
Duloxetine Side Effects Report #5118387-3
DULOXETINE problem was reported by a Health Professional from GREECE on Sept 08, 2006. Female patient, 50 years of age, weighting 132.3 lb, was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: depersonalisation, restlessness, suicide attempt. DULOXETINE dosage: 60 MG, 2/D, ORAL. During the same period patient was treated with SEROQUEL, TRANXENE. Patient recovered.
Duloxetine Side Effects Report #5118391-5
Physician from DENMARK reported DULOXETINE problem on Sept 08, 2006. Female patient, 56 years of age, was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: skin haemorrhage. DULOXETINE dosage: 60 MG, ORAL. During the same period patient was treated with TAMOXIFEN CITRATE, ACETAMINOPHEN, PINEX, DOLOL. Patient was hospitalized. Patient recovered.
Duloxetine Side Effects Report #5122742-5
DULOXETINE problem was reported by a Physician from UNITED STATES on Sept 15, 2006. Female patient, 70 years of age, weighting 315.5 lb, was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: constipation, intestinal obstruction. DULOXETINE dosage: 30 MG, 2/D, ORAL. During the same period patient was treated with XANAX, STALEVO, SINEMET, NEXIUM. Patient was hospitalized. Patient recovered.
Duloxetine Side Effects Report #5129133-1
Health Professional from GREECE reported DULOXETINE problem on Sept 22, 2006. Female patient, 50 years of age, weighting 132.3 lb, was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: depersonalisation, restlessness, suicide attempt. DULOXETINE dosage: 60 MG, 2/D, ORAL. During the same period patient was treated with SEROQUEL, TRANXENE. Patient recovered.
Duloxetine Side Effects Report #5129147-1
DULOXETINE problem was reported by a Pharmacist from GREECE on Sept 22, 2006. Female patient, 75 years of age, was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: condition aggravated, depression, suicidal ideation. DULOXETINE dosage: 60 MG, DAILY (1/D), ORAL. During the same period patient was treated with ZOLOFT, ZYBAN. Patient was hospitalized. Patient recovered.
Duloxetine Side Effects Report #5130619-4
Physician from UNITED STATES reported DULOXETINE problem on Oct 18, 2006. Female patient, 19 years of age, weighting 244.0 lb, was diagnosed with major depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: cholelithiasis, pancreatitis acute. DULOXETINE dosage: 90 MG QD PO. Patient was hospitalized. Patient recovered.
Duloxetine Side Effects Report #5133145-1
DULOXETINE problem was reported by a Health Professional from UNITED KINGDOM on Sept 28, 2006. Female patient, 26 years of age, was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: obsessive thoughts. DULOXETINE dosage: 90 + 30 MG, UNK, ORAL - SEE IMAGE. During the same period patient was treated with PROPRANOLOL. Patient recovered.
Duloxetine Side Effects Report #5135193-4
Pharmacist from UNITED STATES reported DULOXETINE problem on Oct 24, 2006. Male patient was diagnosed with neuropathy and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: hypotension. DULOXETINE dosage: 60 MG DAILY PO. During the same period patient was treated with ALPRAZOLAM, ASPIRIN, GABAPENTIN, HYDROCHLOROTHIAZIDE, LACTULOSE, METOPROLOL TARTRATE, MORPHINE. Patient recovered.
Duloxetine Side Effects Report #5135238-1
DULOXETINE problem was reported by a Pharmacist from UNITED STATES on Oct 24, 2006. Male patient was diagnosed with depression, pain and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: fall, fatigue. DULOXETINE dosage: 60 MG DAILY PO. During the same period patient was treated with DOCUSATE, FERROUS SULPHATE, FINASTERIDE, FLUNISOLIDE NASAL, FUROSEMIDE, NPH INSULIN, LANSOPRAZOLE. Patient recovered.
Duloxetine Side Effects Report #5135768-2
Pharmacist from UNITED STATES reported DULOXETINE problem on Oct 24, 2006. Male patient was diagnosed with pain and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: hyperhidrosis, photophobia, somnolence. DULOXETINE dosage: 60 MG DAILY PO. During the same period patient was treated with ALBUTEROL, ASPIRIN, DOCUSATE, FELODIPINE, FLUNISOLIDE NASAL, GLYBURIDE, TRIAMTERENE AND HYDROCHLOROTHIAZIDE, METFORMIN. Patient recovered.
Duloxetine Side Effects Report #5141763-X
DULOXETINE problem was reported by a Physician from HUNGARY on Oct 05, 2006. Female patient, 50 years of age, was diagnosed with major depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: bradycardia, brain stem syndrome, completed suicide, hypotonia, intentional overdose, locked-in syndrome, miosis, salivary hypersecretion, tremor. DULOXETINE dosage: 30 MG, DAILY (1/D), ORAL. Patient was hospitalized. Patient died on 08/04/2006.
Duloxetine Side Effects Report #5143217-3
Physician from GERMANY reported DULOXETINE problem on Oct 11, 2006. Female patient, 66 years of age, was diagnosed with urinary incontinence and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, gamma-glutamyltransferase increased, upper limb fracture. DULOXETINE dosage: 40 MG, ORAL. During the same period patient was treated with SIMVASTATIN, ASPIRIN. Patient was hospitalized. Patient recovered.
Duloxetine Side Effects Report #5142670-9
DULOXETINE problem was reported by a Physician from HUNGARY on Oct 19, 2006. Male patient, 62 years of age, was diagnosed with major depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: cough, tremor. DULOXETINE dosage: 60 MG, DAILY (1/D). Patient recovered.
Duloxetine Side Effects Report #5144732-9
Physician from BELGIUM reported DULOXETINE problem on Sept 11, 2006. Male patient, 80 years of age, weighting 138.9 lb, was diagnosed with depression, insomnia, chronic obstructive pulmonary disease and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: chronic obstructive pulmonary disease. DULOXETINE dosage: 60 MG, DAILY (1/D). During the same period patient was treated with DULOXETINE HYDROCHLORIDE, TEMESTA, ZOLADEX, OMEPRAZOLE, DUOVENT, SERETIDE EVOHALER, XANTHIUM, SPIRIVA. Patient died on 06/27/2006.
Duloxetine Side Effects Report #5145244-9
DULOXETINE problem was reported by a Physician from on Oct 26, 2006. Female patient, 30 years of age, was diagnosed with depression and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: gamma-glutamyltransferase increased. DULOXETINE dosage: 60 MG, DAILY (1/D). During the same period patient was treated with MIANSERIN, MIRTAZAPINE, NEURO, XANAX, RIVOTRIL. Patient recovered.
Duloxetine Side Effects Report #5145255-3
Physician from NETHERLANDS reported DULOXETINE problem on Oct 11, 2006. Female patient, 88 years of age, weighting 127.9 lb, was diagnosed with depression, hypertension, dyspepsia and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: acute myocardial infarction. DULOXETINE dosage: unknown. During the same period patient was treated with ADALAT, METOPROLOL TARTRATE, RAMIPRIL, OMEPRAZOLE, TEMAZEPAM, NOVOMIX. Patient died on 05/23/2006.
Duloxetine Side Effects Report #5149893-3
DULOXETINE problem was reported by a Physician from BELGIUM on Sept 11, 2006. Male patient, 80 years of age, weighting 138.9 lb, was diagnosed with depression, insomnia, chronic obstructive pulmonary disease and was treated with DULOXETINE. After drug was administered, patient experienced the following problems/side effects: chronic obstructive pulmonary disease. DULOXETINE dosage: 60 MG, DAILY (1/D). During the same period patient was treated with DULOXETINE HYDROCHLORIDE, TEMESTA, ZOLADEX, OMEPRAZOLE, DUOVENT, SERETIDE EVOHALER, XANTHIUM, SPIRIVA. Patient was hospitalized. Patient died on 06/27/2006.
Showing 1-50 of 144 Next >
Drug Information: Duloxetine
URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a604030.html
(doo lox' e teen)IMPORTANT WARNING:
| A small number of children, teenagers, and young adults (up to 24 years of age) who took antidepressants ('mood elevators') such as duloxetine during clinical studies became suicidal (thinking about harming or killing oneself or planning or trying to do so). Children, teenagers, and young adults who take antidepressants to treat depression or other mental illnesses may be more likely to become suicidal than children, teenagers, and young adults who do not take antidepressants to treat these conditions. However, experts are not sure about how great this risk is and how much it should be considered in deciding whether a child or teenager should take an antidepressant. Children younger than 18 years of age should not normally take duloxetine, but in some cases, a doctor may decide that duloxetine is the best medication to treat a child's condition.You should know that your mental health may change in unexpected ways when you take duloxetine or other antidepressants even if you are an adult over age 24. These changes may occur even if you do not have a mental illness and you are taking duloxetine to treat a different type of condition. You may become suicidal, especially at the beginning of your treatment and any time that your dose is increased or decreased. You, your family, or caregiver should call your doctor right away if you experience any of the following symptoms: new or worsening depression; thinking about harming or killing yourself, or planning or trying to do so; extreme worry; agitation; panic attacks; difficulty falling asleep or staying asleep; aggressive behavior; irritability; acting without thinking; severe restlessness; and frenzied abnormal excitement. Be sure that your family or caregiver knows which symptoms may be serious so they can call the doctor when you are unable to seek treatment on your own.Your healthcare provider will want to see you often while you are taking duloxetine, especially at the beginning of your treatment. Be sure to keep all appointments for office visits with your doctor.The doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with duloxetine. Read the information carefully and ask your doctor or pharmacist if you have any questions. You also can obtain the Medication Guide from the FDA website: http://www.fda.gov/cder/drug/antidepressants/antidepressants_MG_2007.pdf.No matter your age, before you take an antidepressant, you, your parent, or your caregiver should talk to your doctor about the risks and benefits of treating your condition with an antidepressant or with other treatments. You should also talk about the risks and benefits of not treating your condition. You should know that having depression or another mental illness greatly increases the risk that you will become suicidal. This risk is higher if you or anyone in your family has or has ever had bipolar disorder (mood that changes from depressed to abnormally excited) or mania (frenzied, abnormally excited mood) or has thought about or attempted suicide. Talk to your doctor about your condition, symptoms, and personal and family medical history. You and your doctor will decide what type of treatment is right for you. |
Why is this medication prescribed?
Duloxetine is used to treat depression and generalized anxiety disorder (GAD; excessive worry and tension that disrupts daily life and lasts for 6 months or longer). Duloxetine is also used to treat pain and tingling caused by diabetic neuropathy (damage to nerves that can develop in people who have diabetes). Duloxetine is in a class of medications called selective serotonin and norepinephrine reuptake inhibitors (SSNRIs). It works by increasing the amounts of serotonin and norepinephrine, natural substances in the brain that help maintain mental balance and stop the movement of pain signals in the brain.
How should this medicine be used?
Duloxetine comes as a delayed release (long-acting) capsule to take by mouth. When duloxetine is used to treat depression, it is usually taken once or twice a day with or without food. When duloxetine is used to treat generalized anxiety disorder or the pain of diabetic neuropathy, it is usually taken once a day with or without food. Take duloxetine at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take duloxetine exactly as directed. Do not take more or less of it, take it more often, or take it for a longer time than prescribed by your doctor.
Swallow the capsules whole; do not split, chew, or crush them. Do not open the capsules and mix the contents with liquids or sprinkle the contents on food.
If you are taking duloxetine to treat generalized anxiety disorder or the pain of diabetic neuropathy, your doctor may start you on a low dose of medication and gradually increase your dose.
Duloxetine may help control your symptoms but will not cure your condition. It may take 1 to 4 weeks or longer before you feel the full benefit of duloxetine. Continue to take duloxetine even if you feel well. Do not stop taking duloxetine without talking to your doctor. Your doctor will probably decrease your dose gradually. If you suddenly stop taking duloxetine, you may experience withdrawal symptoms such as dizziness, nausea, vomiting, headache, pain, burning or tingling in the hands or feet, irritability, and nightmares.Tell your doctor if you experience any of these symptoms when your dose of duloxetine is decreased.
Other uses for this medicine
Duloxetine is also sometimes used to treat stress urinary incontinence (leakage of urine during physical activity such as coughing, sneezing, laughing, and exercise) in women. Talk to your doctor about using this medication to treat your condition.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking duloxetine,
- tell your doctor and pharmacist if you are allergic to duloxetine or any other medications.
- tell your doctor if you are taking thioridazine or a monoamine oxidase (MAO) inhibitor, such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate), or if you have stopped taking an MAO inhibitor within the past 14 days. Your doctor will probably tell you not to take duloxetine. If you stop taking duloxetine, you should wait at least 5 days before you start to take an MAO inhibitor.
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin); antidepressants such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); antihistamines; cimetidine (Tagamet); diuretics ('water pills'); linezolid (Zyvox); medications for irregular heartbeat such as amiodarone (Cordarone), flecainide (Tambocor), moricizine (Ethmozine), quinidine (Quinidex) and propafenone (Rythmol); medications for anxiety, high blood pressure, mental illness, pain, and nausea; propranolol (Inderal); medications for migraine headaches such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), and zolmitriptan (Zomig); lithium (Eskalith, Lithobid); proton pump inhibitors such as lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), and rabeprazole (Aciphex); quinolone antibiotics such as ciprofloxacin (Cipro) and enoxacin (Penetrex); sedatives; certain selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox) and paroxetine (Paxil); sibutramine (Meridia); sleeping pills; theophylline (Theochron, Theolair); tramadol (Ultram); and tranquilizers. Many other medications may interact with duloxetine, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor what herbal products you are taking, especially products containing St. John's wort or tryptophan.
- tell your doctor if you have or have ever had glaucoma (an eye condition). Your doctor may tell you that you should not take duloxetine.
- tell your doctor if you drink or have ever drunk large amounts of alcohol or if you use or have ever used street drugs or have ever overused prescription medications. Also tell your doctor if you have or have ever had a heart attack; high blood pressure; seizures; coronary artery disease (blockage or narrowing of the blood vessels that lead to the heart; or heart, liver, or kidney disease. If you have diabetes, be sure to talk to your doctor about how serious your condition is so your doctor can decide if duloxetine is right for you.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking duloxetine, call your doctor.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking duloxetine.
- you should know that duloxetine may make you drowsy or dizzy. Do not drive a car or operate machinery until you know how this medication affects you.
- ask your doctor about the safe use of alcoholic beverages while you are taking duloxetine..Alcohol can increase the risk of serious side effects from duloxetine.
- you should know that duloxetine may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. This is more common when you first start taking duloxetine. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.
What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
Duloxetine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- nausea
- vomiting
- constipation
- diarrhea
- heartburn
- stomach pain
- decreased appetite
- dry mouth
- increased urination
- difficulty urinating
- sweating or night sweats
- dizziness
- headache
- extreme tiredness
- weakness
- muscle pain or cramps
- changes in sexual desire or ability
- uncontrollable shaking of a part of the body
Some side effects can be serious. If you experience any of the following side effects, or those mentioned in the IMPORTANT WARNING section, call your doctor immediately:
- unusual bruising or bleeding
- pain in the upper right part of the stomach
- itching
- yellowing of the skin or eyes
- dark colored urine
- flu-like symptoms
- blurred vision
- fever
- blisters
- rash
- hives
- swelling of the eyes, face, lips, tongue, throat, hands, arms, feet, ankles, or lower legs
- difficulty breathing or swallowing
Duloxetine may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].
What storage conditions are needed for this medicine?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Symptoms of overdose may include:
- agitation
- hallucinating (seeing things or hearing voices that do not exist)
- fast heartbeat
- fever
- loss of coordination
- nausea
- vomiting
- diarrhea
- drowsiness
- seizures
What other information should I know?
Keep all appointments with your doctor.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
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