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Effexor Side Effects

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Effexor Safety Reports reported to FDA

Total Effexor reports: 1075.
Effexor FDA safety alerts: 2004 2005 2006 .
Reported deaths: 98    Reported hospitalizations: 435.
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Reported Effexor Side Effects: anxiety, condition aggravated, nausea, suicidal ideation, depression, feeling abnormal, headache, insomnia, completed suicide, confusional state, dizziness.
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If you have questions about Effexor, you can ask a Health Expert or Ask Patient Community about Effexor.

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Effexor Side Effects Report #5234568-2
Health Professional from UNITED STATES reported EFFEXOR problem on Jan 29, 2007. Male patient, weighting 156.1 lb, was diagnosed with depression and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, alcohol use, anxiety, compulsions, condition aggravated, crying, depression, dizziness. EFFEXOR dosage: unknown. During the same period patient was treated with WELLBUTRIN, DOXYCYCLINE HYCLATE, RHINOCORT, AMOXICILLIN. Patient was hospitalized. Patient recovered.

Effexor Side Effects Report #5235550-1
EFFEXOR problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 08, 2007. Male patient, 46 years of age, weighting 240.0 lb, was diagnosed with anxiety and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: fear, feeling abnormal, marital problem, suicidal ideation. EFFEXOR dosage: unknown. Patient recovered.

Effexor Side Effects Report #5235750-0
Health Professional from NETHERLANDS reported EFFEXOR problem on Feb 06, 2007. Male patient, weighting 174.2 lb, was diagnosed with panic reaction, dementia alzheimer's type and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: atrioventricular block complete, circulatory collapse. EFFEXOR dosage: unknown. During the same period patient was treated with METFORMIN, PANTOZOL, CRESTOR, PREDNISONE, ACTONEL, EXELON, AVANDIA. Patient was hospitalized. Patient recovered.

Effexor Side Effects Report #5235842-6
EFFEXOR problem was reported by a Physician from UNITED STATES on Feb 07, 2007. Female patient, weighting 127.1 lb, was diagnosed with anxiety and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: anxiety, asthenia, blood potassium decreased, blood sodium decreased, condition aggravated, decreased appetite, diarrhoea, dizziness. EFFEXOR dosage: unknown. During the same period patient was treated with ESTROGENS, SYNTHROID, PROGESTERONE. Patient was hospitalized. Patient recovered.

Effexor Side Effects Report #5236952-X
Health Professional from FRANCE reported EFFEXOR problem on Feb 01, 2007. Female patient, 93 years of age, was diagnosed with dysthymic disorder, arrhythmia, essential hypertension and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: bone pain, haematoma, induration, oedema peripheral, pain in extremity, skin warm. EFFEXOR dosage: unknown. During the same period patient was treated with CORDARONE, LASIX, CALCIPARINE, PREPACOL, NEXIUM. Patient was hospitalized. Patient recovered.

Effexor Side Effects Report #5237204-4
EFFEXOR problem was reported by a Health Professional from FRANCE on Feb 02, 2007. Male patient, 23 years of age, weighting 154.3 lb, was diagnosed with psychotic disorder, brief psychotic disorder with marked stressors and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: aggression, agitation, alanine aminotransferase increased, aspartate aminotransferase increased, dehydration, delirium, dry mouth, dry skin, hyperreflexia. EFFEXOR dosage: unknown. During the same period patient was treated with THERALENE, TERCIAN, SOLIAN. Patient was hospitalized. Patient recovered.

Effexor Side Effects Report #5237703-5
Physician from UNITED STATES reported EFFEXOR problem on Feb 09, 2007. Male patient, weighting 209.2 lb, was diagnosed with depression, hypercholesterolaemia, high density lipoprotein decreased, tachyarrhythmia, diabetes mellitus and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: myocardial infarction. EFFEXOR dosage: unknown. During the same period patient was treated with NIASPAN, WELLBUTRIN, TRAZODONE, TENORMIN, LANOXIN, GLUCOPHAGE, GLUCOTROL. Patient died on 06/11/2006.

Effexor Side Effects Report #5237796-5
EFFEXOR problem was reported by a Health Professional from SWITZERLAND on Feb 02, 2007. Female patient, 82 years of age, weighting 90.39 lb, was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: injection site haematoma, injection site induration. EFFEXOR dosage: unknown. During the same period patient was treated with ASPIRIN, VITARUBIN, CLEXANE. Patient was hospitalized. Patient recovered.

Effexor Side Effects Report #5238073-9
Health Professional from UNITED STATES reported EFFEXOR problem on Feb 09, 2007. Female patient, weighting 67.00 lb, was diagnosed with anxiety, depression and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: muscle rigidity, trismus. EFFEXOR dosage: 37.5 MG. DAILY PO. Patient recovered.

Effexor Side Effects Report #5238438-5
EFFEXOR problem was reported by a Health Professional from NETHERLANDS on Feb 06, 2007. Female patient, weighting 136.7 lb, was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: disturbance in attention, feeling cold, hyperhidrosis, memory impairment, myalgia, oral pain, photophobia, stomatitis, visual acuity reduced. EFFEXOR dosage: unknown. During the same period patient was treated with FLURAZEPAM, ZOLPIDEM TARTRATE. Patient recovered.

Effexor Side Effects Report #5238440-3
Health Professional from NETHERLANDS reported EFFEXOR problem on Feb 06, 2007. Male patient, weighting 264.6 lb, was diagnosed with depression and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: chronic obstructive pulmonary disease, cough, productive cough. EFFEXOR dosage: 150 MG EVERY. During the same period patient was treated with NIFEDIPINE, METOPROLOL TARTRATE, SIMVASTATIN, LOSEC MUPS. Patient recovered.

Effexor Side Effects Report #5238443-9
EFFEXOR problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 05, 2007. Female patient, weighting 215.2 lb, was diagnosed with depression, gastrooesophageal reflux disease and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: nausea. EFFEXOR dosage: unknown. During the same period patient was treated with LIPITOR, LISINOPRIL, PROTONIX. Patient recovered.

Effexor Side Effects Report #5238494-4
Health Professional from SWITZERLAND reported EFFEXOR problem on Feb 07, 2007. Male patient, 33 years of age, was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: aggression, elevated mood, euphoric mood, grandiosity, impulsive behaviour, insomnia, irritability, mania. EFFEXOR dosage: 150 MG EVERY. Patient was hospitalized. Patient recovered.

Effexor Side Effects Report #5239430-7
EFFEXOR problem was reported by a Health Professional from UNITED STATES on Feb 14, 2007. Female patient, weighting 168.1 lb, was diagnosed with osteoporosis, anxiety, hyperlipidaemia, neuropathy, hypertension and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: cardiac failure. EFFEXOR dosage: unknown. During the same period patient was treated with FOSAMAX, XANAX, CRESTOR, LYRICA, ALCOHOL, LISINOPRIL. Patient died on 11/01/2006.

Effexor Side Effects Report #5239432-0
Physician from UNITED STATES reported EFFEXOR problem on Feb 05, 2007. Female patient, weighting 111.1 lb, was diagnosed with depression and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: abnormal dreams, confusional state, dry mouth, dysphagia, flatulence, gallbladder pain, pancreatic disorder, tremor, unevaluable event. EFFEXOR dosage: 150 MG IN THE MORNING AND 150 MG BEFORE BED. During the same period patient was treated with OSCAL. Patient was hospitalized. Patient recovered.

Effexor Side Effects Report #5239433-2
EFFEXOR problem was reported by a Health Professional from UNITED STATES on Feb 07, 2007. Male patient, weighting 156.1 lb, was diagnosed with depression and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, alcohol use, anxiety, brain damage, compulsions, condition aggravated, convulsion, crying, depression. EFFEXOR dosage: unknown. During the same period patient was treated with WELLBUTRIN, DOXYCYCLINE HYCLATE, RHINOCORT, AMOXICILLIN. Patient was hospitalized. Patient recovered.

Effexor Side Effects Report #5239831-7
Consumer or non-health professional from UNITED STATES reported EFFEXOR problem on Feb 14, 2007. Male patient, 61 years of age, weighting 250.0 lb, was diagnosed with depression, fibromyalgia and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: aggression, agitation, depression, fibromyalgia, hallucination, visual, pain, stress, suicidal ideation. EFFEXOR dosage: unknown. Patient recovered.

Effexor Side Effects Report #5241155-9
EFFEXOR problem was reported by a Physician from FRANCE on Feb 12, 2007. Male patient, weighting 198.4 lb, was diagnosed with depression, anxiety, insomnia and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: atonic urinary bladder, condition aggravated, dysuria, epilepsy, hydronephrosis, hypertension, urinary incontinence, urinary retention. EFFEXOR dosage: 150 MG TOTAL DAILY. During the same period patient was treated with TEMESTA, LEPTICUR, PIPORTIL. Patient was hospitalized. Patient recovered.

Effexor Side Effects Report #5241241-3
Consumer or non-health professional from UNITED STATES reported EFFEXOR problem on Feb 12, 2007. Female patient was diagnosed with postpartum depression and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: congenital anomaly, hypoplastic left heart syndrome, myocardial infarction, neonatal multi-organ failure, pregnancy. EFFEXOR dosage: 75MG ONCE DAILY PO. Patient died on 12/09/2006.

Effexor Side Effects Report #5241419-9
EFFEXOR problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 12, 2007. Male patient, 23 years of age, weighting 160.0 lb, was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: completed suicide. EFFEXOR dosage: unknown. Patient died on 10/11/2006.

Effexor Side Effects Report #5241700-3
Health Professional from UNITED KINGDOM reported EFFEXOR problem on Feb 08, 2007. Female patient, 54 years of age, was diagnosed with depression and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: arthralgia, postmenopausal haemorrhage. EFFEXOR dosage: unknown. During the same period patient was treated with LEVOTHYROXINE. Patient recovered.

Effexor Side Effects Report #5242324-4
EFFEXOR problem was reported by a Consumer or non-health professional from AUSTRALIA on Feb 15, 2007. Female patient, 59 years of age, was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: dyskinesia, emotional disorder, nausea, paraesthesia, vomiting. EFFEXOR dosage: unknown. Patient recovered.

Effexor Side Effects Report #5242940-X
Health Professional from SWITZERLAND reported EFFEXOR problem on Feb 09, 2007. Male patient, 42 years of age, weighting 187.4 lb, was diagnosed with depression, panic disorder with agoraphobia, anxiety and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: calculus urinary, diabetes insipidus, hepatic enzyme increased, hypertensive encephalopathy, hypokalaemia, hypothyroidism, polycythaemia, renal failure, ventricular hypertrophy. EFFEXOR dosage: unknown. During the same period patient was treated with QUILONORM, LORAZEPAM, ZOLPIDEM TARTRATE. Patient was hospitalized. Patient recovered.

Effexor Side Effects Report #5243658-X
EFFEXOR problem was reported by a Physician from SWITZERLAND on Feb 12, 2007. Female patient, 73 years of age, was diagnosed with depression, gastritis and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, atrial flutter, chest pain, conduction disorder, hypotension. EFFEXOR dosage: unknown. During the same period patient was treated with SIRDALUD, PANTOZOL, ALDACTONE. Patient was hospitalized. Patient recovered.

Effexor Side Effects Report #5243866-8
Consumer or non-health professional from UNITED STATES reported EFFEXOR problem on Feb 20, 2007. Female patient, 49 years of age, weighting 184.0 lb, was diagnosed with depression and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: communication disorder, diarrhoea, disorientation, disturbance in attention, electric shock, feeling abnormal, headache, hot flush. EFFEXOR dosage: 75 MG 1 TAB SID PO. Patient recovered.

Effexor Side Effects Report #5244058-9
EFFEXOR problem was reported by a Health Professional from FRANCE on Feb 19, 2007. Female patient, 57 years of age, weighting 143.3 lb, was diagnosed with dysthymic disorder and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: blood pressure systolic increased, electrocardiogram qt prolonged, face injury, fall, syncope. EFFEXOR dosage: 75 MG TOTAL DAILY. Patient was hospitalized. Patient recovered.

Effexor Side Effects Report #5245357-7
Physician from NEW ZEALAND reported EFFEXOR problem on Feb 13, 2007. Female patient, 16 years of age, was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: blood creatinine increased, feeling jittery, headache, renal impairment, vomiting. EFFEXOR dosage: unknown. Patient was hospitalized. Patient recovered.

Effexor Side Effects Report #5245447-9
EFFEXOR problem was reported by a Physician from SWITZERLAND on Feb 12, 2007. Female patient, 73 years of age, was diagnosed with depression, gastritis and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, atrial flutter, chest pain, conduction disorder, hypotension. EFFEXOR dosage: unknown. During the same period patient was treated with SIRDALUD, PANTOZOL, ALDACTONE. Patient was hospitalized. Patient recovered.

Effexor Side Effects Report #5246786-8
Physician from UNITED STATES reported EFFEXOR problem on Feb 15, 2007. Female patient, weighting 224.2 lb, was diagnosed with bipolar disorder, hypothyroidism and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: idiopathic thrombocytopenic purpura. EFFEXOR dosage: ^DIFFERENT STRENGTHS VARYING FROM 300 MG TO 37.5 MG^. During the same period patient was treated with SYNTHROID. Patient recovered.

Effexor Side Effects Report #5247438-0
EFFEXOR problem was reported by a Physician from UNITED STATES on Feb 23, 2007. Male patient, weighting 200.0 lb, was diagnosed with depression and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: gun shot wound, intentional self-injury. EFFEXOR dosage: 150MG PO. Patient died on 12/04/2006.

Effexor Side Effects Report #5248656-8
Consumer or non-health professional from UNITED STATES reported EFFEXOR problem on Feb 26, 2007. Female patient, 51 years of age, weighting 270.0 lb, was diagnosed with depression and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: dizziness, mental impairment, nausea, pain in extremity, restless legs syndrome. EFFEXOR dosage: 150 MG ONCE DAILY PO. Patient recovered.

Effexor Side Effects Report #5252264-2
EFFEXOR problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 27, 2007. Female patient, 28 years of age, weighting 135.0 lb, was diagnosed with major depression and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: dizziness, fatigue, feeling abnormal, mood swings, nausea. EFFEXOR dosage: unknown. Patient recovered.

Effexor Side Effects Report #5322081-3
Physician from UNITED STATES reported EFFEXOR problem on Sept 22, 2006. Female patient, 60 years of age, was diagnosed with depression and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: pancytopenia. EFFEXOR dosage: 37.5 MG 1X PER 1 DAY; ORAL. During the same period patient was treated with GLIPIZIDE, METFORMIN, TRIAMTERENE, OXYBUTYNIN HYDROCHLORIDE. Patient recovered.

Effexor Side Effects Report #5322082-5
EFFEXOR problem was reported by a Consumer or non-health professional from UNITED STATES on Mar 01, 2006. Male patient, 80 years of age, was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: completed suicide. EFFEXOR dosage: unknown. Patient died on 03/13/2004.

Effexor Side Effects Report #5322113-2
Consumer or non-health professional from UNITED STATES reported EFFEXOR problem on Oct 03, 2006. Male patient, 32 years of age, was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: completed suicide. EFFEXOR dosage: unknown. Patient died on 09/04/2004.

Effexor Side Effects Report #5322115-6
EFFEXOR problem was reported by a Consumer or non-health professional from UNITED STATES on Oct 26, 2006. Female patient, 57 years of age, was diagnosed with depression, convulsion and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: convulsion. EFFEXOR dosage: 375 MG 1X PER 1 DAY; ORAL. During the same period patient was treated with BUSPAR, FLUOXETINE, KEPPRA, WELLBUTRIN. Patient recovered.

Effexor Side Effects Report #5322117-X
Physician from UNITED STATES reported EFFEXOR problem on Oct 30, 2006. Male patient, 50 years of age, was diagnosed with anxiety disorder and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: convulsion. EFFEXOR dosage: unknown. During the same period patient was treated with LEXAPRO. Patient recovered.

Effexor Side Effects Report #5322120-X
EFFEXOR problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 10, 2006. Male patient, 70 years of age, was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: suicide attempt. EFFEXOR dosage: unknown. During the same period patient was treated with NEURONTIN. Patient was hospitalized. Patient recovered.

Effexor Side Effects Report #5252256-3
Physician from SWITZERLAND reported EFFEXOR problem on Feb 26, 2007. Male patient, 19 years of age, was diagnosed with depression and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: anxiety, completed suicide, insomnia. EFFEXOR dosage: unknown. During the same period patient was treated with ZYPREXA. Patient died on 03/12/2004.

Effexor Side Effects Report #5253332-1
EFFEXOR problem was reported by a Physician from SWITZERLAND on Feb 26, 2007. Female patient, 76 years of age, was diagnosed with depression and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: abdominal discomfort, hyponatraemia. EFFEXOR dosage: unknown. During the same period patient was treated with AMLODIPINE, METOPROLOL SUCCINATE, ZESTORETIC, TEMESTA. Patient was hospitalized. Patient recovered.

Effexor Side Effects Report #5254152-4
Physician from SWITZERLAND reported EFFEXOR problem on Feb 23, 2007. Female patient, 73 years of age, was diagnosed with depression, gastritis and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, atrial flutter, chest pain, conduction disorder, hypotension. EFFEXOR dosage: unknown. During the same period patient was treated with SIRDALUD, PANTOZOL, ALDACTONE. Patient was hospitalized. Patient recovered.

Effexor Side Effects Report #5254153-6
EFFEXOR problem was reported by a Health Professional from FRANCE on Feb 23, 2007. Female patient, 50 years of age, was diagnosed with depression and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: alcohol poisoning, iron deficiency anaemia, overdose, suicide attempt. EFFEXOR dosage: 100 MG TOTAL DAILY. During the same period patient was treated with LEVOTHYROXINE, ETHANOL, TRIATEC, TAHOR, KARDEGIC, LEXOMIL. Patient was hospitalized. Patient recovered.

Effexor Side Effects Report #5254155-X
Health Professional from SWITZERLAND reported EFFEXOR problem on Feb 26, 2007. Male patient, 42 years of age, weighting 187.4 lb, was diagnosed with depression, panic disorder with agoraphobia, anxiety and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, anxiety, aspartate aminotransferase increased, borrelia burgdorferi serology positive, calculus urinary, convulsion, diabetes insipidus, gamma-glutamyltransferase increased, hepatic enzyme increased. EFFEXOR dosage: unknown. During the same period patient was treated with QUILONORM, LORAZEPAM, ZOLPIDEM TARTRATE. Patient was hospitalized. Patient recovered.

Effexor Side Effects Report #5254798-3
EFFEXOR problem was reported by a Health Professional from UNITED STATES on Mar 01, 2007. Female patient, weighting 180.0 lb, was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: anxiety, blood pressure increased, chills, confusional state, diarrhoea, feeling abnormal, feeling cold, headache. EFFEXOR dosage: unknown. Patient recovered.

Effexor Side Effects Report #5254919-2
Physician from UNITED KINGDOM reported EFFEXOR problem on Jan 10, 2007. Female patient, 40 years of age, was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: hepatomegaly, oedema peripheral. EFFEXOR dosage: unknown. Patient recovered.

Effexor Side Effects Report #5256944-4
EFFEXOR problem was reported by a Physician from SWITZERLAND on Feb 27, 2007. Female patient, 54 years of age, was diagnosed with listless and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: condition aggravated, disorientation, disturbance in attention, restlessness, schizoaffective disorder, suicidal ideation, thinking abnormal. EFFEXOR dosage: 75 TO 150 MG PER DAY. During the same period patient was treated with LAMICTAL, METOPROLOL SUCCINATE, CLOZAPINE. Patient recovered.

Effexor Side Effects Report #5256947-X
Physician from FRANCE reported EFFEXOR problem on Mar 01, 2007. Female patient, 37 years of age, was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: abdominal pain, angioedema, arthralgia, urticaria chronic. EFFEXOR dosage: unknown. Patient was hospitalized. Patient recovered.

Effexor Side Effects Report #5258379-7
EFFEXOR problem was reported by a Physician from SWITZERLAND on Feb 28, 2007. Male patient, 49 years of age, was diagnosed with depression and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood cholesterol increased, blood triglycerides increased, gamma-glutamyltransferase increased. EFFEXOR dosage: 75 MG AND INCREASING DOSES. During the same period patient was treated with OMEPRAZOLE, REMERON. Patient recovered.

Effexor Side Effects Report #5258765-5
Health Professional from UNITED STATES reported EFFEXOR problem on Mar 06, 2007. Female patient, weighting 114.0 lb, was diagnosed with anxiety and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: erythema multiforme. EFFEXOR dosage: 37.5MG ONCE DAILY PO. During the same period patient was treated with ABILIFY. Patient recovered.

Effexor Side Effects Report #5259043-0
EFFEXOR problem was reported by a Health Professional from UNITED KINGDOM on Feb 28, 2007. Female patient, 52 years of age, was diagnosed with depression, anxiety and was treated with EFFEXOR. After drug was administered, patient experienced the following problems/side effects: blood pressure decreased, heart rate increased, neutropenia, paraesthesia. EFFEXOR dosage: unknown. Patient was hospitalized. Patient recovered.

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Drug Information: Venlafaxine

URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a694020.html

(ven' la fax een)

IMPORTANT WARNING:

A small number of children, teenagers, and young adults (up to 24 years of age) who took antidepressants ('mood elevators') such as venlafaxine during clinical studies became suicidal (thinking about harming or killing oneself or planning or trying to do so). Children, teenagers, and young adults who take antidepressants to treat depression or other mental illnesses may be more likely to become suicidal than children, teenagers, and young adults who do not take antidepressants to treat these conditions. However, experts are not sure about how great this risk is and how much it should be considered in deciding whether a child or teenager should take an antidepressant. Children younger than 18 years of age should not normally take venlafaxine, but in some cases, a doctor may decide that venlafaxine is the best medication to treat a child's condition.You should know that your mental health may change in unexpected ways when you take venlafaxine or other antidepressants even if you are an adult over age 24. You may become suicidal, especially at the beginning of your treatment and any time that your dose is increased or decreased. You, your family, or your caregiver should call your doctor right away if you experience any of the following symptoms: new or worsening depression; thinking about harming or killing yourself, or planning or trying to do so; extreme worry; agitation; panic attacks; difficulty falling asleep or staying asleep; aggressive behavior; irritability; acting without thinking; severe restlessness; and frenzied abnormal excitement. Be sure that your family or caregiver knows which symptoms may be serious so they can call the doctor when you are unable to seek treatment on your own.Your healthcare provider will want to see you often while you are taking venlafaxine, especially at the beginning of your treatment. Be sure to keep all appointments for office visits with your doctor.The doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with venlafaxine. Read the information carefully and ask your doctor or pharmacist if you have any questions. You also can obtain the Medication Guide from the FDA website: http://www.fda.gov/cder/drug/antidepressants/antidepressants_MG_2007.pdf.No matter your age, before you take an antidepressant, you, your parent, or your caregiver should talk to your doctor about the risks and benefits of treating your condition with an antidepressant or with other treatments. You should also talk about the risks and benefits of not treating your condition. You should know that having depression or another mental illness greatly increases the risk that you will become suicidal. This risk is higher if you or anyone in your family has or has ever had bipolar disorder (mood that changes from depressed to abnormally excited) or mania (frenzied, abnormally excited mood) or has thought about or attempted suicide. Talk to your doctor about your condition, symptoms, and personal and family medical history. You and your doctor will decide what type of treatment is right for you.

Why is this medication prescribed?

Venlafaxine is used to treat depression. Venlafaxine extended-release (long-acting) capsules are also used to treat generalized anxiety disorder (excessive worrying that is difficult to control), social anxiety disorder (extreme fear of interacting with others or performing in front of others that interferes with normal life), and panic disorder (sudden, unexpected attacks of extreme fear and worry about these attacks). Venlafaxine is in a class of medications called selective serotonin and norepinephrine reuptake inhibitors (SNRIs). It works by increasing the amounts of serotonin and norepinephrine, natural substances in the brain that help maintain mental balance.

How should this medicine be used?

Venlafaxine comes as a tablet or extended-release capsule to take by mouth. The tablet is usually taken two or three times a day with food. The extended-release capsule is usually taken once daily in the morning or evening with food. Take venlafaxine at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take venlafaxine exactly as directed. Do not take more or less of it or take it more often or for a longer period of time than prescribed by your doctor.

Swallow the extended-release capsule whole; do not split, chew or crush it, or place it in water. If you cannot swallow the extended-release capsule, you may carefully open the capsule and sprinkle the entire contents on a spoonful of applesauce. Swallow (without chewing) this mixture immediately after preparation and then drink a glass of water to make sure that you have swallowed all of the medication.

Your doctor will probably start you on a low dose of venlafaxine and gradually increase your dose, not more often than once every 4 to 7 days. Tell your doctor how you are feeling during your treatment so that your doctor can adjust your dose properly.

Venlafaxine controls depression but does not cure it. It may take 6 to 8 weeks or longer for you to feel the full benefit of this medication. Continue to take venlafaxine even if you feel well. Do not stop taking venlafaxine without talking to your doctor. Your doctor will probably decrease your dose gradually. If you suddenly stop taking venlafaxine, you may experience withdrawal symptoms such as agitation; anxiety; confusion; sad mood; irritability; frenzied or abnormal excitement; lack of coordination; trouble falling asleep or staying asleep; nightmares; nausea; vomiting; loss of appetite; diarrhea; dry mouth; sweating; ringing in the ears; seizures; or burning, tingling, numbness, or electric shock-like feelings in any part of the body. Tell your doctor if you experience any of these symptoms while you are decreasing your dose of venlafaxine or soon after you stop taking venlafaxine.

Other uses for this medicine

Venlafaxine is also sometimes used to treat hot flashes (hot flushes; sudden strong feelings of heat and sweating) in women who have experienced menopause ('change of life'; the end of monthly menstrual periods) or who are taking medication to treat breast cancer. Talk to your doctor or pharmacist about the risks of using venlafaxine to treat your condition.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking venlafaxine,

  • tell your doctor and pharmacist if you are allergic to venlafaxine, any other medications, or any of the ingredients in venlafaxine tablets or extended-release capsules. Ask your pharmacist for a list of the ingredients.
  • tell your doctor if you are taking a monoamine oxidase (MAO) inhibitor, such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate), or if you have stopped taking one of these medications within the past 14 days. Your doctor will probably tell you that you should not take venlafaxine. If you stop taking venlafaxine, your doctor will tell you that you should wait at least 7 days before you start to take an MAO inhibitor.
  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, or nutritional supplements you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin); amiodarone (Cordarone, Pacerone); other antidepressants; cimetidine (Tagamet); clozapine (Clozaril); diuretics ('water pills'); duloxetine (Cymbalta); haloperidol (Haldol); imipramine (Tofranil); indinavir (Crixivan); ketoconazole (Nizoral); linezolid (Zyvox); lithium; medications for anxiety, mental illness, pain, seizures, or weight loss; medications for migraine such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), and zolmitriptan (Zomig); methadone (Dolophine); phentermine (Adipex P, Ionamin); ritonavir (Norvir); sedatives; selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), and sertraline (Zoloft); sibutramine (Meridia); sleeping pills; tramadol (Ultram); and tranquilizers. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor what nutritional supplements and herbal products you are taking, especially St. John's wort and tryptophan.
  • tell your doctor if you have ever used illegal drugs or overused prescription medications. Also tell your doctor if you have recently had a heart attack and if you have or have ever had high blood pressure, high blood cholesterol glaucoma (an eye disease), high pressure in the eyes (a condition that can lead to glaucoma), seizures, or heart, kidney, liver, or thyroid disease.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking venlafaxine, call your doctor.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking venlafaxine.
  • you should know that this medication may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.
  • remember that alcohol can add to the drowsiness caused by this medication.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are taking the extended-release capsules, do not take more than one dose per day.

What side effects can this medication cause?

Venlafaxine may cause side effects. Call your doctor if any of the following symptoms are severe or do not go away:

  • drowsiness
  • weakness or tiredness
  • dizziness
  • headache
  • nightmares
  • nausea
  • vomiting
  • stomach pain
  • constipation
  • diarrhea
  • gas
  • heartburn
  • burping
  • dry mouth
  • change in ability to taste food
  • loss of appetite
  • weight loss
  • uncontrollable shaking of a part of the body
  • pain, burning, numbness, or tingling in part of the body
  • muscle tightness
  • twitching
  • yawning
  • sweating
  • hot flashes or flushing
  • frequent urination
  • difficulty urinating
  • sore throat, chills, or other signs of infection
  • ringing in the ears
  • changes in sexual desire or ability
  • enlarged pupils (black circles in the middle of the eyes)

Some side effects can be serious. If you experience any of the following symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately:

  • rash
  • hives
  • itching
  • difficulty breathing or swallowing
  • chest pain
  • fast, pounding, or irregular heartbeat
  • seizures
  • unusual bruising or bleeding
  • small purple spots on the skin
  • eye pain or redness
  • changes in vision
  • fever
  • problems with coordination
  • hallucinations (seeing things or hearing voices that do not exist)
  • coma (loss of consciousness for a period of time)

Venlafaxine may slow growth and weight gain in children. If your child is taking venlafaxine, your child's doctor will watch your child's growth carefully. Talk to your child's doctor about the risks of giving venlafaxine to your child.

Venlafaxine may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include:

  • dizziness
  • nausea
  • vomiting
  • burning, tingling, or numbness of the hands and feet
  • increased size of the pupil (black center of the eye)
  • muscle pain
  • hot and cold spells
  • sleepiness
  • seizures
  • fast, slow, or irregular heartbeat
  • coma (loss of consciousness for a period of time)

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will check your blood pressure often and order certain lab tests to check your response to venlafaxine.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand name(s):

  • Effexor®
  • Effexor® XR

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