Eloxatin Side Effects
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Eloxatin Safety Reports reported to FDA
Total Eloxatin reports: 98.Eloxatin FDA safety alerts: No.
Reported deaths: 15 Reported hospitalizations: 52.
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Reported Eloxatin Side Effects: laryngospasm, chills, vomiting, pyrexia, dyspnoea, pulmonary embolism, dyspnoea exertional, anaphylactic reaction, hyperhidrosis, fatigue, hypersensitivity.
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Showing 1-50 of 98 Next >
Eloxatin Side Effects Report #5060943-5Physician from UNITED STATES reported ELOXATIN problem on Apr 19, 2006. Male patient, weighting 209.0 lb, was diagnosed with colon cancer and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, chills, diffuse alveolar damage, gastrointestinal haemorrhage, intestinal ischaemia, lung consolidation, lung infiltration. ELOXATIN dosage: unknown. During the same period patient was treated with CALCIUM GLUCONATE, MAGNESIUM, DECADRON, ALOXI, LEUCOVORIN CALCIUM, FLUOROURACIL. Patient was hospitalized. Patient died on 04/22/2006.
Eloxatin Side Effects Report #5062575-1
ELOXATIN problem was reported by a Health Professional from UNITED KINGDOM on July 19, 2006. Female patient was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: cerebrovascular accident. ELOXATIN dosage: unknown. Patient recovered.
Eloxatin Side Effects Report #5064730-3
Health Professional from UNITED KINGDOM reported ELOXATIN problem on July 21, 2006. Female patient, 77 years of age, weighting 188.5 lb, was diagnosed with colorectal cancer and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: laryngospasm. ELOXATIN dosage: unknown. Patient was hospitalized. Patient recovered.
Eloxatin Side Effects Report #5064733-9
ELOXATIN problem was reported by a Health Professional from UNITED KINGDOM on July 24, 2006. Female patient, 65 years of age, weighting 187.6 lb, was diagnosed with colorectal cancer and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: feeling abnormal, laryngospasm, neuropathy peripheral, tremor. ELOXATIN dosage: unknown. Patient recovered.
Eloxatin Side Effects Report #5069822-0
Physician from GERMANY reported ELOXATIN problem on May 18, 2006. Female patient, weighting 130.1 lb, was diagnosed with colon cancer, prophylaxis of nausea and vomiting and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: abdominal pain, aphasia, motor dysfunction. ELOXATIN dosage: unknown. During the same period patient was treated with KEVATRIL, RIBOFOLIN, FLUOROURACIL. Patient was hospitalized. Patient recovered.
Eloxatin Side Effects Report #5078483-6
ELOXATIN problem was reported by a Health Professional from FRANCE on Aug 03, 2006. Female patient, 58 years of age, was diagnosed with colorectal cancer and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: back pain, chest discomfort, chills, cyanosis, peripheral coldness, pyrexia. ELOXATIN dosage: unknown. Patient was hospitalized. Patient recovered.
Eloxatin Side Effects Report #5078948-7
Consumer or non-health professional from UNITED STATES reported ELOXATIN problem on Aug 09, 2006. Male patient, weighting 222.7 lb, was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: deep vein thrombosis, pulmonary embolism. ELOXATIN dosage: 185 MG. During the same period patient was treated with LEUCOVORIN CALCIUM, FLUOROURACIL. Patient was hospitalized. Patient recovered.
Eloxatin Side Effects Report #5083642-2
ELOXATIN problem was reported by a Pharmacist from UNITED STATES on June 21, 2006. Female patient was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: haemolytic anaemia, interstitial lung disease. ELOXATIN dosage: unknown. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM, AVASTIN. Patient recovered.
Eloxatin Side Effects Report #5083664-1
Physician from GERMANY reported ELOXATIN problem on Aug 14, 2006. Female patient was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: depressed level of consciousness, hypotonia. ELOXATIN dosage: unknown. Patient recovered.
Eloxatin Side Effects Report #5087725-2
ELOXATIN problem was reported by a Health Professional from GREECE on Aug 16, 2006. Male patient, 67 years of age, weighting 198.4 lb, was diagnosed with hypertension, diabetes mellitus non-insulin-dependent, vomiting and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: erythema, hot flush, hypoaesthesia, prolonged expiration. ELOXATIN dosage: unknown. During the same period patient was treated with LISINOPRIL, LOPERAMIDE, GLIMEPIRIDE, DOLASETRON, CALCIUM FOLINATE. Patient recovered.
Eloxatin Side Effects Report #5093064-6
Pharmacist from UNITED STATES reported ELOXATIN problem on Aug 22, 2006. Female patient, 76 years of age, weighting 100.1 lb, was diagnosed with colon cancer metastatic and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: cough, laryngitis, laryngospasm. ELOXATIN dosage: unknown. During the same period patient was treated with PROPRANOLOL, HYDROCHLOROTHIAZIDE, LEUCOVORIN CALCIUM, FLUOROURACIL. Patient recovered.
Eloxatin Side Effects Report #5100004-X
ELOXATIN problem was reported by a Consumer or non-health professional from UNITED STATES on Sept 06, 2006. Male patient, weighting 160.1 lb, was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, cerebral atrophy, cerebral ventricle dilatation, dehydration, dry mouth, eyelid ptosis, guillain-barre syndrome, hyperhidrosis. ELOXATIN dosage: 160 MG. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM. Patient was hospitalized. Patient recovered.
Eloxatin Side Effects Report #5102844-X
Health Professional from UNITED STATES reported ELOXATIN problem on June 01, 2006. Female patient, 79 years of age, was diagnosed with colorectal cancer stage iii and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: anaphylactic shock, apnoea, cardio-respiratory arrest, malaise. ELOXATIN dosage: unknown. During the same period patient was treated with COUMADIN, LEUCOVORIN, FLUOROURACIL. Patient was hospitalized. Patient recovered.
Eloxatin Side Effects Report #5102866-9
ELOXATIN problem was reported by a Health Professional from PORTUGAL on Sept 06, 2006. Female patient was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: asphyxia, chest pain, erythema. ELOXATIN dosage: unknown. Patient recovered.
Eloxatin Side Effects Report #5104928-9
Consumer or non-health professional from UNITED STATES reported ELOXATIN problem on Sept 08, 2006. Female patient, weighting 226.2 lb, was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: acidosis, arrhythmia, chest pain, dilatation ventricular, dyspnoea, hypoxia, lung infiltration, orthostatic hypotension, pulmonary embolism. ELOXATIN dosage: 180 MG. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM. Patient was hospitalized. Patient died on 09/02/2006.
Eloxatin Side Effects Report #5104945-9
ELOXATIN problem was reported by a Health Professional from GREECE on Aug 16, 2006. Male patient, 67 years of age, weighting 198.4 lb, was diagnosed with hypertension, diabetes mellitus non-insulin-dependent, vomiting and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: erythema, hot flush, hypoaesthesia, prolonged expiration. ELOXATIN dosage: unknown. During the same period patient was treated with LISINOPRIL, LOPERAMIDE, GLIMEPIRIDE, DOLASETRON, CALCIUM FOLINATE. Patient recovered.
Eloxatin Side Effects Report #5108215-4
Health Professional from UNITED STATES reported ELOXATIN problem on Sept 06, 2006. Female patient, 65 years of age, weighting 113.1 lb, was diagnosed with colorectal cancer metastatic and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: retinitis pigmentosa. ELOXATIN dosage: unknown. During the same period patient was treated with XELODA. Patient recovered.
Eloxatin Side Effects Report #5125152-X
ELOXATIN problem was reported by a Physician from ITALY on Nov 15, 2005. Male patient, 74 years of age, was diagnosed with rectal cancer stage iii and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: acute respiratory distress syndrome, cardiac failure, cough, dyspnoea, interstitial lung disease, neutropenia, renal failure, thrombocytopenia. ELOXATIN dosage: unknown. During the same period patient was treated with LEUCOVORINE, FLUOROURACIL. Patient was hospitalized. Patient died on 12/26/2005.
Eloxatin Side Effects Report #5125155-5
Health Professional from SPAIN reported ELOXATIN problem on Oct 03, 2006. Female patient was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: hypersensitivity, respiratory arrest. ELOXATIN dosage: unknown. Patient recovered.
Eloxatin Side Effects Report #5127107-8
ELOXATIN problem was reported by a Physician from BELGIUM on Oct 06, 2006. Female patient was diagnosed with colorectal cancer and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: haemolysis, hepatitis, intravascular haemolysis, thrombocytopenia. ELOXATIN dosage: unknown. Patient recovered.
Eloxatin Side Effects Report #5139773-1
Physician from UNITED STATES reported ELOXATIN problem on Apr 19, 2006. Male patient, weighting 209.0 lb, was diagnosed with colon cancer stage iii and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: asthenia, atrial fibrillation, chills, dyspnoea, fall, gastrointestinal haemorrhage, hypersensitivity, idiopathic pulmonary fibrosis. ELOXATIN dosage: unknown. During the same period patient was treated with CALCIUM GLUCONATE, MAGNESIUM, DECADRON, ALOXI, LEUCOVORIN CALCIUM, FLUOROURACIL. Patient was hospitalized. Patient died on 04/21/2006.
Eloxatin Side Effects Report #5140368-4
ELOXATIN problem was reported by a Health Professional from UNITED STATES on Oct 26, 2006. Male patient, 51 years of age, was diagnosed with rectal cancer and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: pneumonia. ELOXATIN dosage: unknown. During the same period patient was treated with AVASTIN, LEUCOVORIN CALCIUM, FLUOROURACIL. Patient was hospitalized. Patient died.
Eloxatin Side Effects Report #5142529-7
Physician from TUNISIA reported ELOXATIN problem on Oct 26, 2006. Male patient, weighting 183.0 lb, was diagnosed with colorectal cancer recurrent and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: hyperhidrosis, hypotension, paraesthesia, shock. ELOXATIN dosage: 170 MG/2W. During the same period patient was treated with FOLINATE CALCIUM. Patient recovered.
Eloxatin Side Effects Report #5146140-3
ELOXATIN problem was reported by a Physician from GERMANY on Nov 03, 2006. Male patient, weighting 165.3 lb, was diagnosed with colon cancer and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: ileus, neoplasm progression. ELOXATIN dosage: unknown. During the same period patient was treated with FOLINIC ACID, FLUOROURACIL. Patient died on 05/23/2005.
Eloxatin Side Effects Report #5153297-7
Physician from GERMANY reported ELOXATIN problem on Nov 07, 2006. Male patient, weighting 246.9 lb, was diagnosed with rectal cancer, epilepsy and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: epilepsy. ELOXATIN dosage: unknown. During the same period patient was treated with METOCLOPRAMIDE, ZOFRAN, TEGRETOL, LEUCOVORIN CALCIUM, FLUOROURACIL. Patient recovered.
Eloxatin Side Effects Report #5155403-7
ELOXATIN problem was reported by a Physician from GERMANY on Sept 07, 2006. Male patient, weighting 185.2 lb, was diagnosed with bile duct cancer, hypertension and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: acute hepatic failure, jaundice, malaise. ELOXATIN dosage: unknown. During the same period patient was treated with DOCITON, GEMCITABINE. Patient was hospitalized. Patient recovered.
Eloxatin Side Effects Report #5159480-9
Pharmacist from UNITED STATES reported ELOXATIN problem on Nov 22, 2006. Female patient, 55 years of age, weighting 233.0 lb, was diagnosed with colon cancer and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: chest discomfort, dyspnoea, hyperhidrosis, nausea, vomiting. ELOXATIN dosage: 180MG Q2WEEKS IV. During the same period patient was treated with AVASTIN, LEUCOVORIN, FLUOROURACIL, ALOXI, DECADRON. Patient was hospitalized. Patient recovered.
Eloxatin Side Effects Report #5162057-2
ELOXATIN problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Oct 25, 2006. Male patient, 47 years of age, was diagnosed with colorectal cancer metastatic and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: cerebrovascular accident. ELOXATIN dosage: 120 MG Q2W. During the same period patient was treated with FLUOROURACIL, CALCIUM FOLINATE, ONDANSETRON, DEXAMETHASONE, METOCLOPRAMIDE. Patient was hospitalized. Patient recovered.
Eloxatin Side Effects Report #5215318-2
Health Professional from UNITED STATES reported ELOXATIN problem on Sept 26, 2006. Female patient was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: anaphylactic reaction, chills, pyrexia, vomiting. ELOXATIN dosage: unknown. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM. Patient was hospitalized. Patient recovered.
Eloxatin Side Effects Report #5215319-4
ELOXATIN problem was reported by a Health Professional from UNITED STATES on Sept 26, 2006. Male patient was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: anaphylactic reaction, chills, laryngeal oedema, pyrexia, vomiting. ELOXATIN dosage: unknown. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM. Patient was hospitalized. Patient recovered.
Eloxatin Side Effects Report #5215320-0
Health Professional from UNITED STATES reported ELOXATIN problem on Sept 26, 2006. Female patient was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: anaphylactic reaction, chills, pyrexia, vomiting. ELOXATIN dosage: unknown. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM. Patient was hospitalized. Patient recovered.
Eloxatin Side Effects Report #5170789-5
ELOXATIN problem was reported by a Consumer or non-health professional from UNITED STATES on Dec 05, 2006. Male patient, weighting 213.8 lb, was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: blood pressure decreased, international normalised ratio abnormal, loss of consciousness, palpitations, pulmonary embolism, refusal of treatment by patient. ELOXATIN dosage: 190 MG. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM. Patient was hospitalized. Patient recovered.
Eloxatin Side Effects Report #5173527-5
Consumer or non-health professional from UNITED STATES reported ELOXATIN problem on Dec 07, 2006. Male patient, weighting 196.4 lb, was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, atelectasis, lung infiltration, pulmonary embolism, pulmonary infarction. ELOXATIN dosage: 175 MG. During the same period patient was treated with LEUCOVORIN CALCIUM, FLUOROURACIL. Patient was hospitalized. Patient recovered.
Eloxatin Side Effects Report #5174410-1
ELOXATIN problem was reported by a Physician from TUNISIA on Oct 26, 2006. Male patient, weighting 183.0 lb, was diagnosed with colorectal cancer recurrent and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: hyperhidrosis, hypotension, paraesthesia, shock. ELOXATIN dosage: 170 MG/2W. During the same period patient was treated with FOLINATE CALCIUM. Patient recovered.
Eloxatin Side Effects Report #5175392-9
Consumer or non-health professional from UNITED STATES reported ELOXATIN problem on Dec 12, 2006. Female patient, weighting 262.4 lb, was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: hypersensitivity, infusion related reaction. ELOXATIN dosage: 16 MG. During the same period patient was treated with LEUCOVORIN CALCIUM, BEVACIZUMAB. Patient was hospitalized. Patient recovered.
Eloxatin Side Effects Report #5383106-2
ELOXATIN problem was reported by a Health Professional from UNITED STATES on June 28, 2007. Male patient, weighting 171.1 lb, was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: rib fracture. ELOXATIN dosage: unknown. During the same period patient was treated with LEUCOVORIN CALCIUM, FLUOROURACIL. Patient recovered.
Eloxatin Side Effects Report #5388040-X
Physician from SLOVAKIA (Slovak Republic) reported ELOXATIN problem on July 09, 2007. Female patient was diagnosed with colorectal cancer and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: agitation, circulatory collapse, depression, suicidal ideation, syncope. ELOXATIN dosage: unknown. Patient recovered.
Eloxatin Side Effects Report #5390342-8
ELOXATIN problem was reported by a Physician from UNITED STATES on July 06, 2007. Female patient, 59 years of age, was diagnosed with colon cancer and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: hepatic cirrhosis. ELOXATIN dosage: unknown. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM. Patient was hospitalized. Patient recovered.
Eloxatin Side Effects Report #5399296-1
Physician from UNITED STATES reported ELOXATIN problem on July 18, 2007. Female patient, 71 years of age, was diagnosed with bile duct cancer and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: ischaemic stroke. ELOXATIN dosage: unknown. During the same period patient was treated with GEMCITABINE. Patient was hospitalized. Patient died.
Eloxatin Side Effects Report #5403918-6
ELOXATIN problem was reported by a Consumer or non-health professional from UNITED STATES on July 31, 2007. Female patient, weighting 190.0 lb, was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: balance disorder, blood pressure systolic decreased, headache, hyperhidrosis, muscle spasms, syncope. ELOXATIN dosage: 160 MG. During the same period patient was treated with FERROUS SULPHATE. Patient was hospitalized. Patient recovered.
Eloxatin Side Effects Report #5409326-6
Physician from CANADA reported ELOXATIN problem on July 27, 2007. Female patient was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: arterial thrombosis limb, peripheral ischaemia. ELOXATIN dosage: unknown. Patient was hospitalized. Patient recovered.
Eloxatin Side Effects Report #5409339-4
ELOXATIN problem was reported by a Physician from SLOVAKIA (Slovak Republic) on July 27, 2007. Female patient was diagnosed with colorectal cancer and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: agitation, circulatory collapse, depression, suicidal ideation, syncope. ELOXATIN dosage: unknown. Patient recovered.
Eloxatin Side Effects Report #5412679-6
Physician from CANADA reported ELOXATIN problem on Aug 07, 2007. Male patient, 61 years of age, was diagnosed with colon cancer and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: arterial thrombosis limb, peripheral ischaemia. ELOXATIN dosage: unknown. Patient was hospitalized. Patient recovered.
Eloxatin Side Effects Report #5418365-0
ELOXATIN problem was reported by a Physician from on June 20, 2007. Male patient, weighting 169.8 lb, was diagnosed with rectal cancer recurrent, ischaemia, hypertension, diabetes mellitus, platelet aggregation inhibition, vomiting and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: dyspnoea, laryngeal oedema, rales, tongue oedema. ELOXATIN dosage: unknown. During the same period patient was treated with PRAVASTATIN, VASTAREL, SOPROL, GLUCOPHAGE, ASASANTINE, FOZITEC, PRIMPERAN. Patient recovered.
Eloxatin Side Effects Report #5419376-1
Pharmacist from UNITED STATES reported ELOXATIN problem on Aug 16, 2007. Male patient, 48 years of age, weighting 290.6 lb, was diagnosed with colorectal cancer metastatic and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: asthenia, muscle spasms, paraesthesia, throat tightness. ELOXATIN dosage: 610 MG ONCE IV. Patient was hospitalized. Patient recovered.
Eloxatin Side Effects Report #5426328-4
ELOXATIN problem was reported by a Physician from SWITZERLAND on Aug 20, 2007. Female patient, 81 years of age, was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: asthenia, eyelid ptosis, iiird nerve paresis, vision blurred. ELOXATIN dosage: unknown. Patient was hospitalized. Patient recovered.
Eloxatin Side Effects Report #5451444-0
Health Professional from UNITED STATES reported ELOXATIN problem on Sept 11, 2007. Female patient, 58 years of age, weighting 266.0 lb, was diagnosed with colon cancer metastatic and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: chest discomfort, oxygen saturation decreased, pruritus. ELOXATIN dosage: 190 MG EVERY 2 WEEKS IV. Patient recovered.
Eloxatin Side Effects Report #5456397-7
ELOXATIN problem was reported by a Health Professional from UNITED STATES on Sept 12, 2007. Male patient, weighting 238.1 lb, was diagnosed with hepatic neoplasm malignant and was treated with ELOXATIN. After drug was administered, patient experienced the following problems/side effects: dehydration, diarrhoea, fatigue, hyperkalaemia, metabolic acidosis, mucosal inflammation, pancreatitis, urinary tract infection. ELOXATIN dosage: unknown. During the same period patient was treated with THORAZINE, SPIRONOLACTONE, PROCHLORPERAZINE, ZOFRAN, QUESTRAN, PHENERGAN, OPIUM TINCTURE, MEGACE. Patient was hospitalized. Patient recovered.
Showing 1-50 of 98 Next >
Drug Information: Oxaliplatin Injection
URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a607035.html
ox al" i pla' tinIMPORTANT WARNING:
| Oxaliplatin may cause severe allergic reactions. These allergic reactions may happen within a few minutes after you receive oxaliplatin and may cause death. Tell your doctor if you are allergic to oxaliplatin, carboplatin (Paraplatin), cisplatin (Platinol) or any other medications. If you experience any of the following symptoms, tell your doctor or other healthcare provider immediately: rash, hives, itching, reddening of the skin, difficulty breathing or swallowing, hoarseness, feeling as if your throat is closing, swelling of the lips and tongue, dizziness, lightheadness, or fainting. |
Why is this medication prescribed?
Oxaliplatin is used with other medications to treat advanced colon or rectal cancer (cancer that begins in the large intestine). Oxaliplatin is also used with other medications to prevent colon cancer from spreading in people who have had surgery to remove the tumor. Oxaliplatin is in a class of medications called platinum-containing antineoplastic agents. It works by killing cancer cells.
How should this medicine be used?
Oxaliplatin comes as a solution (liquid) to be injected into a vein. Oxaliplatin is administered by a doctor or nurse. It is usually given once every fourteen days.
Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before using oxaliplatin,
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention oral anticoagulants ('blood thinners') such as warfarin (Coumadin). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor if you have or have ever had kidney disease.
- tell your doctor if you are pregnant or plan to become pregnant. Oxaliplatin may harm the fetus. You should use birth control to prevent pregnancy during your treatment with oxaliplatin. Talk to your doctor about types of birth control that will work for you.If you become pregnant while taking oxaliplatin, call your doctor. Do not breast-feed during your treatment with oxaliplatin.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are using oxaliplatin.
- you should know that oxaliplatin may decrease your ability to fight infection. Stay away from people who are sick during your treatment with oxaliplatin.
- you should know that exposure to cold air or objects may make some of the side effects of oxaliplatin worse. You should not eat or drink anything colder than room temperature, touch any cold objects, go near air conditioners or freezers, wash your hands in cold water, or go outside in cold weather unless absolutely necessary for five days after you receive each dose of oxaliplatin. If you must go outside in cold weather, wear a hat, gloves, and a scarf, and cover your mouth and nose.
What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
Do not eat or drink anything that is colder than room temperature for five days after you receive each dose of oxaliplatin.
What should I do if I forget a dose?
Call your doctor as soon as possible if you are unable to keep an appointment to receive oxaliplatin. It is very important that you receive your treatment on schedule.
What side effects can this medication cause?
Oxaliplatin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- numbness, burning, or tingling in the fingers, toes, hands, feet, mouth, or throat
- pain in the hands or feet
- increased sensitivity, especially to cold
- decreased sense of touch
- nausea
- vomiting
- diarrhea
- constipation
- gas
- stomach pain
- heartburn
- sores in the mouth
- loss of appetite
- change in the ability to taste food
- weight gain or loss
- hiccups
- dry mouth
- muscle, back, or joint pain
- tiredness
- anxiety
- depression
- difficulty falling asleep or staying asleep
- hair loss
- dry skin
- redness or peeling of the skin on the hands and feet
- sweating
- flushing
Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately:
- stumbling or loss of balance when walking
- difficulty with everyday activities such as writing or fastening buttons
- difficulty speaking
- strange feeling in the tongue
- tightening of the jaw
- chest pain or pressure
- cough
- shortness of breath
- sore throat, fever, chills, and other signs of infection
- pain, redness, or swelling in the place where oxaliplatin was injected
- pain when urinating
- decreased urination
- unusual bruising or bleeding
- nosebleed
- blood in urine
- vomit that is bloody or looks like coffee grounds
- bright red blood in stool
- black and tarry stools
- pale skin
- weakness
- problems with vision
- swelling of the arms, hands, feet, ankles, or lower legs
Oxaliplatin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Symptoms of overdose may include:
- shortness of breath
- wheezing
- numbness or tingling in the fingers or toes
- vomiting
- chest pain
- slowed breathing
- slowed heartbeat
- tightening of the throat
- diarrhea
What other information should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to oxaliplatin.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Brand name(s):
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