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Endep Side Effects

Common Endep Side Effects


The most commonly reported Endep side effects (click to view or check a box to report):

Dry Mouth (8)
Urinary Retention (3)
Dysuria (2)
Dysgeusia (2)
Anxiety (2)
Anorexia (2)
Hallucination (2)
Gingivitis (2)
Pulmonary Embolism (2)
Hyperhidrosis (2)
Oral Candidiasis (2)
Sensitivity Of Teeth (2)
Nausea (2)
Lip Dry (2)
Rash Erythematous (1)
Self-injurious Ideation (1)
Pyrexia (1)
Product Quality Issue (1)
Pollakiuria (1)
Pruritus (1)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

Endep Side Effects Reported to FDA

The following Endep reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.


The appearance of Endep on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.
Memory Impairment, Confusional State, Speech Disorder
This is a report of a 82-year-old female patient (weight: NA) from AU, suffering from the following symptoms/conditions: neuralgia,blood pressure, who was treated with Endep (dosage: NA, start time: Jun 20, 2013), combined with:
  • Monoplus
  • Solian
  • Acimax
  • Aspirin
and developed a serious reaction and side effect(s). The consumer presented with:
  • Memory Impairment
  • Confusional State
  • Speech Disorder
which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Endep treatment in female patients, resulting in memory impairment side effect. The patient was hospitalized.

Hypoaesthesia Oral, Rash Erythematous, Hypersensitivity, Pruritus, Oedema Mouth
This report suggests a potential Endep Hypoaesthesia Oral, Rash Erythematous, Hypersensitivity, Pruritus, Oedema Mouth side effect(s) that can have serious consequences. A 63-year-old male patient (weight: NA) from AUSTRALIA was diagnosed with the following symptoms/conditions: NA and used Endep (dosage: NA) starting NS. Soon after starting Endep the patient began experiencing various side effects, including:
  • Hypoaesthesia Oral
  • Rash Erythematous
  • Hypersensitivity
  • Pruritus
  • Oedema Mouth
Drugs used concurrently:
  • Cartia Xt
  • Karvea
  • Zydol - Slow Release (100 Mg, As Needed)
  • Zyloprim
  • Atorvastatin Calcium (40 Mg, 1x/day)
  • Spiriva
The patient was hospitalized. Although Endep demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as hypoaesthesia oral, may still occur.

Cerebrovascular Accident
This Cerebrovascular Accident problem was reported by a consumer or non-health professional from AUSTRALIA. A 46-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On Sep 01, 2010 this consumer started treatment with Endep (dosage: Unk). The following drugs were being taken at the same time:
  • Botulinum Toxin Type A (Unk)
  • Inderal /00030001/ (Unk)
When commencing Endep, the patient experienced the following unwanted symptoms/side effects:
  • Cerebrovascular Accident
Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as cerebrovascular accident, may become evident only after a product is in use by the general population.

Mantle Cell Lymphoma
This is a report of a 82-year-old female patient (weight: NA) from AUSTRALIA. The patient developed the following symptoms/conditions: anxiety and was treated with Endep (dosage: NA) starting Jun 04, 2010. Concurrently used drugs:
  • Panamax
  • Prolia (60 Mg, Unk)
  • Lyrica
  • Temazepam
  • Ezetimibe (10 Mg, Qd)
  • Coveram (5 Mg, Qd)
  • Dexamethasone
Soon after that, the consumer experienced the following side effects:
  • Mantle Cell Lymphoma
The patient was hospitalized. This opens a possibility that Endep treatment could cause the above reactions, including mantle cell lymphoma, and some female subjects may be more susceptible.


Vulval Cellulitis
A female patient (weight: NA) from AUSTRALIA with the following symptoms/conditions: NA started Endep treatment (dosage: NA) on Dec 13, 2010. Soon after starting Endep treatment, the subject experienced various side effects, including:
  • Vulval Cellulitis
Concurrently used drugs:
  • Prednisone
  • Clotrimazole
  • Estradiol
  • Golimumab
  • Temaze
  • Irbesartan + Hydrochlorothiazide
  • Spiriva
  • Rabeprazole Sodium
The patient was hospitalized. This finding indicates that some female patients could be more vulnerable to Endep.

Product Quality Issue
A 58-year-old male patient from AUSTRALIA (weight: NA) experienced symptoms, such as: NA and was treated with Endep(dosage: NA). The treatment was initiated on NS. After that a consumer reported the following side effect(s):
  • Product Quality Issue
Concurrently used drugs, which potentially could have contributed to side effect(s) or affected Endep efficacy:
  • Mobic
  • Duragesic-100
  • Zoloft
  • Duragesic-100
  • Emadine Se
  • Xanax


Iiird Nerve Paralysis
In this report, Endep was administered for the following condition: post herpetic neuralgia.A 76-year-old female consumer from AUSTRALIA (weight: NA) started Endep treatment (dosage: NA) on Mar 03, 2009.Sometime after starting the treatment, the patient complained of the following side effect(s):
  • Iiird Nerve Paralysis
A possible interaction with other drugs could have contributed to this reaction:
  • Lyrica
  • Lyrica
  • Prednisolone
The patient was hospitalized.Establishing a causal relationship between a specific drug and consumer's side effects is complex, but it is possible that in this report Endep treatment could be related to the listed above side effect(s).

Breast Cancer, Chest Pain, Palpitations, Pulmonary Embolism, Tremor
This is a report of the following Endep side effect(s):
  • Breast Cancer
  • Chest Pain
  • Palpitations
  • Pulmonary Embolism
  • Tremor
A 49-year-old female patient from AUSTRALIA (weight: NA) presented with the following condition: pain and received a treatment with Endep (dosage: NA) starting: Feb 23, 2009.The following concurrently used drugs could have generated interactions: NA.The patient was hospitalized.This report suggests that a Endep treatment could be associated with the listed above side effect(s).

Pulmonary Embolism
This Endep report was submitted by a 49-year-old female consumer from AUSTRALIA (weight: NA). The patient was diagnosed with: pain and Endep was administered (dosage: 10 Mg;daily; Oral) starting: Feb 23, 2009. The consumer developed a set of symptoms:
  • Pulmonary Embolism
Other drugs used simultaneously: NA.The patient was hospitalized.Those unexpected symptoms could be linked to a Endep treatment, however establishing a potential drug-safety problem requires a more detailed clinical analysis.

Feeling Hot, Nausea, Syncope
This is a report of a possible correlation between Endep use and the following symptoms/side effect(s):
  • Feeling Hot
  • Nausea
  • Syncope
which could contribute to an assessment of Endep risk profile.A 64-year-old female consumer from AUSTRALIA (weight: NA) was suffering from depression and was treated with Endep (dosage: 25 Mg, Daily, Oral) starting Jan 01, 2002.Other concurrent medications:
  • Zomig


Depression
A 73-year-old female patient from AUSTRALIA (weight: NA) presented with the following symptoms: anxiety and after a treatment with Endep (dosage: 5 Mg;at Bedtime; Oral) experienced the following side effect(s):
  • Depression
The treatment was started on Nov 25, 2008. Endep was used in combination with the following drugs:
  • Xanax
  • Cardizem
  • Nexium
This report could alert potential Endep consumers.

Open Angle Glaucoma
In this report, a 53-year-old female patient from AUSTRALIA (weight: NA) was affected by a possible Endep side effect.The patient was diagnosed with insomnia,tension headache. After a treatment with Endep (dosage: 50 Mg;at Bedtime; Oral, start date: Jan 01, 1990), the patient experienced the following side effect(s):
  • Open Angle Glaucoma
The following simultaneously used drugs could have led to this reaction: NA.The findings here stress that side effects should be taken into consideration when evaluating a Endep treatment.

Abnormal Sleep-related Event, Dry Mouth, Gingivitis, Oral Candidiasis, Pollakiuria, Sensitivity Of Teeth, Urinary Retention
This is a report of a 43-year-old female patient from AUSTRALIA (weight: NA), who used Endep (dosage: 150 Mg; At Bedtime; Oral, 125 Mg; At Bedtime; Oral, 100 Mg; At Bedtime; Oral) for a treatment of neuralgia. After starting a treatment on Jul 23, 2008, the patient experienced the following side effect(s):
  • Abnormal Sleep-related Event
  • Dry Mouth
  • Gingivitis
  • Oral Candidiasis
  • Pollakiuria
  • Sensitivity Of Teeth
  • Urinary Retention
The following drugs could possibly have interacted with the Endep treatment NA.Taken together, these observations suggest that a Endep treatment could be related to side effect(s), such as Abnormal Sleep-related Event, Dry Mouth, Gingivitis, Oral Candidiasis, Pollakiuria, Sensitivity Of Teeth, Urinary Retention.

Dry Mouth, Dysgeusia, Hallucination, Hyperhidrosis, Illusion, Lip Dry
This dry mouth side effect was reported by a consumer or non-health professional from AUSTRALIA. A 69-year-old female patient (weight:NA) experienced the following symptoms/conditions: anxiety. The patient was prescribed Endep (dosage: 50 Mg; At Bedtime; Oral), which was started on Jan 01, 2007. Concurrently used drugs:
  • Protos(con.)
  • Brufen /00109201/ (con.)
  • Rani (con.)
  • Aratac (con.)
  • Avapro (con.)
  • Warfarin (con.)
  • Zocor (con.)
When starting to take Endep the consumer reported the following symptoms:
  • Dry Mouth
  • Dysgeusia
  • Hallucination
  • Hyperhidrosis
  • Illusion
  • Lip Dry
These side effects may potentially be related to Endep.

Bladder Disorder, Dry Mouth, Dysuria, Gingivitis, Oral Candidiasis, Sensitivity Of Teeth, Sleep Disorder, Urinary Retention
This is a Endep side effect report of a 43-year-old female patient (weight:NA) from AUSTRALIA, suffering from the following symptoms/conditions: neuralgia, who was treated with Endep (dosage:150 Mg; At Bedtime; Oral, start time: Dec 01, 2005), combined with:
  • Trifeme
  • Lyrica
  • Neurontin
  • Ditropan
  • Panadeine
  • Vesicare
  • Coloxyl With Senna
  • Avanza
, and developed a serious reaction and a bladder disorder side effect. The patient presented with:
  • Bladder Disorder
  • Dry Mouth
  • Dysuria
  • Gingivitis
  • Oral Candidiasis
  • Sensitivity Of Teeth
  • Sleep Disorder
  • Urinary Retention
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Endep treatment in female patients suffering from neuralgia, resulting in bladder disorder.

Condition Aggravated, Dry Mouth, Dysgeusia, Hallucination, Hyperhidrosis, Lip Dry
This report suggests a potential Endep condition aggravated side effect(s) that can have serious consequences. A 69-year-old female patient from AUSTRALIA (weight:NA) was diagnosed with the following health condition(s): anxiety and used Endep (dosage: 50 Mg; At Bedtime; Oral) starting Jan 01, 2007. Soon after starting Endep the patient began experiencing various side effects, including:
  • Condition Aggravated
  • Dry Mouth
  • Dysgeusia
  • Hallucination
  • Hyperhidrosis
  • Lip Dry
Drugs used concurrently:
  • Protos
  • Brufen
  • Rani
  • Aratac
  • Avapro
  • Warfarin Sodium
  • Zocor
Although Endep demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as condition aggravated, may still occur.

Anorexia, Chills, Dry Mouth, Gait Disturbance, Influenza, Myalgia, Nausea, Pharyngolaryngeal Pain, Pyrexia
This anorexia problem was reported by a physician from AUSTRALIA. A 64-year-old male patient (weight: NA) was diagnosed with the following medical condition(s): depression.On Apr 04, 2008 a consumer started treatment with Endep (dosage: 50 Mg; Daily; Oral). The following drugs/medications were being taken at the same time:
  • Metformin Hcl
  • Prednisone Tab
  • Zocor
  • Pantoprazole Sodium
  • Myocrisin
When commencing Endep, the patient experienced the following unwanted symptoms /side effects:
  • Anorexia
  • Chills
  • Dry Mouth
  • Gait Disturbance
  • Influenza
  • Myalgia
  • Nausea
  • Pharyngolaryngeal Pain
  • Pyrexia
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as anorexia, may become evident only after a product is in use by the general population.

Abnormal Behaviour, Anorexia, Anxiety, Convulsion, Mood Altered, Spousal Abuse, Stress, Suicidal Ideation
This is a Endep side effect report of a 29-year-old female patient (weight: NA) from AUSTRALIA. The patient developed the following symptoms/conditions: depression and was treated with Endep (dosage: Oral) starting Feb 08, 2008. Concurrently used drugs:
  • Tramadol Hcl (Oral)
  • Restavit
  • Digesic
Soon after that, the consumer experienced the following of symptoms:
  • Abnormal Behaviour
  • Anorexia
  • Anxiety
  • Convulsion
  • Mood Altered
  • Spousal Abuse
  • Stress
  • Suicidal Ideation
This opens a possibility that Endep could cause abnormal behaviour and that some female patients may be more susceptible.

Blood Electrolytes Abnormal, Dizziness, Fall, Somnolence, Transient Ischaemic Attack, Upper Limb Fracture
A 76-year-old female patient (weight: NA) from AUSTRALIA with the following symptoms: depression started Endep (amitriptyline Hydrochloride) (50 Mg) treatment (dosage: 50 Mg;at Bedtime;oral) on Jan 01, 2008. Soon after starting Endep (amitriptyline Hydrochloride) (50 Mg) treatment, the consumer experienced several side effects, including:
  • Blood Electrolytes Abnormal
  • Dizziness
  • Fall
  • Somnolence
  • Transient Ischaemic Attack
  • Upper Limb Fracture
. Concurrently used drugs: NA.The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Endep (amitriptyline Hydrochloride) (50 Mg) side effects, such as blood electrolytes abnormal.

Dry Mouth, Dysuria, Eye Pain, Hallucination, Auditory, Insomnia, Paraesthesia, Sensation Of Heaviness
This dry mouth side effect was reported by a consumer or non-health professional from AUSTRALIA. A 55-year-old female patient (weight:NA) experienced the following symptoms/conditions: depression.The patient was prescribed Endep (dosage: 20 Mg; At Bedtime; Oral), which was started on Jan 01, 2006. Concurrently used drugs:
  • Lipitor
  • Ural
.When starting to take Endep the consumer reported symptoms, such as:
  • Dry Mouth
  • Dysuria
  • Eye Pain
  • Hallucination, Auditory
  • Insomnia
  • Paraesthesia
  • Sensation Of Heaviness
These side effects may potentially be related to Endep.

Dry Mouth, Tardive Dyskinesia, Trismus, Vision Blurred
This is a report of a 75-year-old female patient (weight: NA) from AUSTRALIA, suffering from the following symptoms/conditions: fibromyalgia, who was treated with Endep (dosage: 25 Mg;nocte;oral, start time: Jan 01, 2002), combined with: NA. and developed a serious reaction and side effect(s). The consumer presented with:
  • Dry Mouth
  • Tardive Dyskinesia
  • Trismus
  • Vision Blurred
which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Endep treatment in female patients, resulting in dry mouth side effect.

Agitation, Anxiety, Delusion, Nightmare, Paranoia, Urinary Retention
This report suggests a potential Endep Agitation, Anxiety, Delusion, Nightmare, Paranoia, Urinary Retention side effect(s) that can have serious consequences. A 33-year-old male patient (weight: NA) from UNITED STATES was diagnosed with the following symptoms/conditions: bone pain,neuralgia and used Endep (dosage: 50 Mg; Hd; Oral; 10 Mg; Hd; Oral) starting Oct 17, 2007. Soon after starting Endep the patient began experiencing various side effects, including:
  • Agitation
  • Anxiety
  • Delusion
  • Nightmare
  • Paranoia
  • Urinary Retention
Drugs used concurrently: NA. Although Endep demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as agitation, may still occur.

Aggression, Dry Mouth, Fatigue, Self-injurious Ideation, Tearfulness
This Aggression, Dry Mouth, Fatigue, Self-injurious Ideation, Tearfulness problem was reported by a consumer or non-health professional from . A 57-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: burning sensation. On Oct 04, 2007 this consumer started treatment with Endep (amitriptyline Hydrochloride) (25 Mg) (dosage: 25 Mg). The following drugs were being taken at the same time: NA. When commencing Endep (amitriptyline Hydrochloride) (25 Mg), the patient experienced the following unwanted symptoms/side effects:
  • Aggression
  • Dry Mouth
  • Fatigue
  • Self-injurious Ideation
  • Tearfulness
Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as aggression, may become evident only after a product is in use by the general population.



Top 10 Endep Side Effects for Women

Women Side EffectsReports
Dry Mouth 7
Dysgeusia 2
Dysuria 2
Gingivitis 2
Hallucination 2
Hyperhidrosis 2
Lip Dry 2
Oral Candidiasis 2
Pulmonary Embolism 2
Sensitivity Of Teeth 2

Top 10 Endep Side Effects for Men

Men Side EffectsReports
Agitation 1
Anorexia 1
Anxiety 1
Chills 1
Delusion 1
Dry Mouth 1
Gait Disturbance 1
Hypersensitivity 1
Hypoaesthesia Oral 1
Influenza 1

Keep Track of Side Effects

Note Your Observations

It is really important to keep of your symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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