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Review Estradiol Safety Reports submitted to FDA

Total Estradiol reports: 23.
Estradiol FDA safety alerts: 2002 2003 2005 2006 .
Reported deaths: 2    Reported hospitalizations: 1.
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FDA Reported Estradiol Side Effects: breast cancer female, hot flush, insomnia, blister, headache, breast cancer metastatic, palpitations, menopausal symptoms, breast cancer stage i, breast cancer, application site irritation.
Estradiol Usage.
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Estradiol Side Effects Report #5655609-4
Health Professional from HUNGARY reported ESTRADIOL problem on Mar 03, 2008. Female patient, 50 years of age, was diagnosed with vaginal haemorrhage and was treated with ESTRADIOL. After drug was administered, patient experienced the following problems/side effects: angiosarcoma, disseminated intravascular coagulation, haemothorax, hepatic haemangioma rupture, pulmonary embolism. ESTRADIOL dosage: unknown. During the same period patient was treated with HEPARIN. Patient died.

Estradiol Side Effects Report #5616348-9
ESTRADIOL problem was reported by a Health Professional from UNITED STATES on Feb 05, 2008. Female patient, 42 years of age, weighting 162.0 lb, was diagnosed with hot flush, menopause and was treated with ESTRADIOL. After drug was administered, patient experienced the following problems/side effects: application site urticaria. ESTRADIOL dosage: unknown. Patient recovered.

Estradiol Side Effects Report #5629313-2
Health Professional from UNITED STATES reported ESTRADIOL problem on Feb 15, 2008. Female patient, weighting 140.0 lb, was treated with ESTRADIOL. After drug was administered, patient experienced the following problems/side effects: skin reaction. ESTRADIOL dosage: 0.0375 MG PATCH CHANGE Q WEEK. Patient recovered.

Estradiol Side Effects Report #5636801-1
ESTRADIOL problem was reported by a Pharmacist from UNITED STATES on Feb 19, 2008. Male patient, 53 years of age, was treated with ESTRADIOL. After drug was administered, patient experienced the following problems/side effects: postmenopausal haemorrhage. ESTRADIOL dosage: 2MG EVERY DAY PO. Patient recovered.

Estradiol Side Effects Report #5590353-3
Consumer or non-health professional from UNITED STATES reported ESTRADIOL problem on Jan 08, 2008. Female patient was treated with ESTRADIOL. After drug was administered, patient experienced the following problems/side effects: breast cancer metastatic. ESTRADIOL dosage: unknown. During the same period patient was treated with PREMARIN, ESTRACE. Patient died on 11/16/2004.

Estradiol Side Effects Report #5574331-6
ESTRADIOL problem was reported by a Consumer or non-health professional from UNITED STATES on Dec 13, 2007. Female patient was diagnosed with parathyroid tumour and was treated with ESTRADIOL. After drug was administered, patient experienced the following problems/side effects: fluid retention, swelling. ESTRADIOL dosage: unknown. During the same period patient was treated with PROVERA. Patient was hospitalized. Patient recovered.

Estradiol Side Effects Report #5577615-0
Consumer or non-health professional from AUSTRALIA reported ESTRADIOL problem on Dec 19, 2007. Female patient, 60 years of age, was treated with ESTRADIOL. After drug was administered, patient experienced the following problems/side effects: breast operation. ESTRADIOL dosage: unknown. Patient recovered.

Estradiol Side Effects Report #5517937-2
ESTRADIOL problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 07, 2007. Female patient, 64 years of age, weighting 150.0 lb, was diagnosed with menopause and was treated with ESTRADIOL. After drug was administered, patient experienced the following problems/side effects: abdominal pain, adrenal mass, anaemia, arterial occlusive disease, breast cancer, breast fibrosis, breast mass, breast microcalcification. ESTRADIOL dosage: 0.05MG. During the same period patient was treated with MEDROXYPROGESTERONE ACETATE, PREMPRO, PREMARIN, PROVERA, ESTRADERM, PROMETRIUM, CYCRIN. Patient recovered.

Estradiol Side Effects Report #5532788-0
Health Professional from UNITED STATES reported ESTRADIOL problem on Nov 30, 2007. Female patient, 50 years of age, weighting 140.0 lb, was diagnosed with ill-defined disorder and was treated with ESTRADIOL. After drug was administered, patient experienced the following problems/side effects: hot flush, night sweats, sleep disorder. ESTRADIOL dosage: .037MG WEEKLY TRANSDERMAL. Patient recovered.

Estradiol Side Effects Report #5504788-8
ESTRADIOL problem was reported by a Health Professional from UNITED STATES on Oct 31, 2007. Female patient was diagnosed with menopausal symptoms and was treated with ESTRADIOL. After drug was administered, patient experienced the following problems/side effects: hot flush. ESTRADIOL dosage: unknown. During the same period patient was treated with SYNTHROID, IMITREX, FIORICET, OXYCODONE. Patient recovered.

Estradiol Side Effects Report #5466662-5
Consumer or non-health professional from UNITED STATES reported ESTRADIOL problem on Sept 21, 2007. Female patient, 36 years of age, weighting 162.2 lb, was diagnosed with hysterectomy and was treated with ESTRADIOL. After drug was administered, patient experienced the following problems/side effects: blister. ESTRADIOL dosage: 0.075MG. Patient recovered.

Estradiol Side Effects Report #5470473-4
ESTRADIOL problem was reported by a Physician from UNITED STATES on Sept 27, 2007. Female patient was diagnosed with depression, menopausal symptoms, sleep disorder and was treated with ESTRADIOL. After drug was administered, patient experienced the following problems/side effects: mental disorder. ESTRADIOL dosage: 0.1 MG/DAY APPLY TO SKIN CHANGE WEEKLY TOPICAL. During the same period patient was treated with CLIMARA. Patient recovered.

Estradiol Side Effects Report #5413206-X
Pharmacist from AUSTRALIA reported ESTRADIOL problem on Aug 10, 2007. Female patient was treated with ESTRADIOL. After drug was administered, patient experienced the following problems/side effects: application site irritation, application site vesicles. ESTRADIOL dosage: unknown. During the same period patient was treated with IRBESARTAN, NORMISON, ATORVASTATIN CALCIUM. Patient recovered.

Estradiol Side Effects Report #5347129-1
ESTRADIOL problem was reported by a Consumer or non-health professional from UNITED STATES on July 07, 2006. Female patient was treated with ESTRADIOL. After drug was administered, patient experienced the following problems/side effects: breast cancer female. ESTRADIOL dosage: unknown. Patient recovered.

Estradiol Side Effects Report #5347307-1
Consumer or non-health professional from UNITED STATES reported ESTRADIOL problem on July 07, 2006. Female patient was treated with ESTRADIOL. After drug was administered, patient experienced the following problems/side effects: breast cancer female. ESTRADIOL dosage: unknown. Patient recovered.

Estradiol Side Effects Report #5347741-X
ESTRADIOL problem was reported by a Consumer or non-health professional from UNITED STATES on July 07, 2006. Female patient was treated with ESTRADIOL. After drug was administered, patient experienced the following problems/side effects: breast cancer female. ESTRADIOL dosage: unknown. Patient recovered.

Estradiol Side Effects Report #5398805-6
Physician from UNITED STATES reported ESTRADIOL problem on July 25, 2007. Female patient was diagnosed with menopause, osteoporosis and was treated with ESTRADIOL. After drug was administered, patient experienced the following problems/side effects: skin reaction. ESTRADIOL dosage: 0.06MG Q WEEK SKIN. Patient recovered.

Estradiol Side Effects Report #5403840-5
ESTRADIOL problem was reported by a Physician from UNITED STATES on July 31, 2007. Female patient, 51 years of age, weighting 139.0 lb, was diagnosed with menopause and was treated with ESTRADIOL. After drug was administered, patient experienced the following problems/side effects: pharmaceutical product counterfeit, withdrawal bleed. ESTRADIOL dosage: unknown. Patient recovered.

Estradiol Side Effects Report #5347129-1
Consumer or non-health professional from UNITED STATES reported ESTRADIOL problem on July 07, 2006. Female patient was treated with ESTRADIOL. After drug was administered, patient experienced the following problems/side effects: breast cancer female. ESTRADIOL dosage: unknown. Patient recovered.

Estradiol Side Effects Report #5347307-1
ESTRADIOL problem was reported by a Consumer or non-health professional from UNITED STATES on July 07, 2006. Female patient was treated with ESTRADIOL. After drug was administered, patient experienced the following problems/side effects: breast cancer female. ESTRADIOL dosage: unknown. Patient recovered.

Estradiol Side Effects Report #5347741-X
Consumer or non-health professional from UNITED STATES reported ESTRADIOL problem on July 07, 2006. Female patient was treated with ESTRADIOL. After drug was administered, patient experienced the following problems/side effects: breast cancer female. ESTRADIOL dosage: unknown. Patient recovered.

Estradiol Side Effects Report #5398805-6
ESTRADIOL problem was reported by a Physician from UNITED STATES on July 25, 2007. Female patient was diagnosed with menopause, osteoporosis and was treated with ESTRADIOL. After drug was administered, patient experienced the following problems/side effects: skin reaction. ESTRADIOL dosage: 0.06MG Q WEEK SKIN. Patient recovered.

Estradiol Side Effects Report #5403840-5
Physician from UNITED STATES reported ESTRADIOL problem on July 31, 2007. Female patient, 51 years of age, weighting 139.0 lb, was diagnosed with menopause and was treated with ESTRADIOL. After drug was administered, patient experienced the following problems/side effects: pharmaceutical product counterfeit, withdrawal bleed. ESTRADIOL dosage: unknown. Patient recovered.


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angiosarcoma, disseminated intravascular coagulation, haemothorax, hepatic haemangioma rupture, pulmonary embolism, , was diagnosed with vaginal haemorrhage and was diagnosed with hot flush, menopause and was diagnosed with parathyroid tumour and