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Etomidate Side Effects

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Common Etomidate Side Effects


The most commonly reported Etomidate side effects (click to view or check a box to report):

Cardiac Arrest (8)
Renal Failure (7)
Unevaluable Event (6)
Bradycardia (6)
Injection Site Phlebitis (5)
Pain (5)
Hypotension (4)
Grand Mal Convulsion (4)
Convulsion (4)
Cerebrovascular Accident (4)
Injury (4)
Loss Of Consciousness (4)
Ventricular Tachycardia (4)
Myoclonus (4)
Anxiety (3)
Death (3)
Tachycardia (3)
Renal Impairment (3)
Tremor (3)
No Therapeutic Response (2)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Etomidate Side Effects Reported to FDA



Etomidate Side Effect Report#9996279
Product Quality Issue, Heart Rate Decreased
This is a report of a 45-year-old male patient (weight: NA) from US, suffering from the following health symptoms/conditions: anaesthesia, who was treated with Etomidate (dosage: NA, start time:
Mar 07, 2014), combined with: NA. and developed a serious reaction and side effect(s): Product Quality Issue, Heart Rate Decreased after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Etomidate treatment in male patients, resulting in Product Quality Issue side effect.
Etomidate Side Effect Report#9929624
Epilepsy
This report suggests a potential Etomidate Epilepsy side effect(s) that can have serious consequences. A 22-year-old female patient (weight: NA) from DE was diagnosed with the following symptoms/conditions: epilepsy and used Etomidate (dosage: 0.1 Mg/kg, Unk) starting NS. After starting Etomidate the patient began experiencing various side effects, including: EpilepsyAdditional drugs used concurrently: NA. Although Etomidate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Epilepsy, may still occur.
Etomidate Side Effect Report#9516779
Infusion Site Cellulitis
This Infusion Site Cellulitis problem was reported by a health professional from US. A 50-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: colonoscopy. On
Jun 21, 2010 this consumer started treatment with Etomidate (dosage: NA). The following drugs were being taken at the same time: NA. When using Etomidate, the patient experienced the following unwanted symptoms/side effects: Infusion Site CellulitisThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Infusion Site Cellulitis, may become evident only after a product is in use by the general population.
Etomidate Side Effect Report#9258643
Tachycardia, Rash, Bronchospasm, Hypertension
This Tachycardia side effect was reported by a pharmacist from US. A 43-year-old male patient (weight:NA) experienced the following symptoms/conditions: sedation.The patient was prescribed Etomidate (drug dosage: NA), which was initiated on
Apr 24, 2013. Concurrently used drugs: NA..After starting to take Etomidate the consumer reported adverse symptoms, such as: Tachycardia, Rash, Bronchospasm, HypertensionThese side effects may potentially be related to Etomidate.
Etomidate Side Effect Report#9010932
Pneumocystis Jirovecii Pneumonia, Blood Cortisol Decreased, Off Label Use
This is a report of a 20-year-old male patient (weight: NA) from CZ, suffering from the following health symptoms/conditions: cushing^s syndrome, who was treated with Etomidate (dosage: NA, start time: NS), combined with:
  • Ketoconazole
and developed a serious reaction and side effect(s): Pneumocystis Jirovecii Pneumonia, Blood Cortisol Decreased, Off Label Use after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Etomidate treatment in male patients, resulting in Pneumocystis Jirovecii Pneumonia side effect.
Etomidate Side Effect Report#9006886
Pneumocystis Jirovecii Pneumonia, Sepsis, Off Label Use
This report suggests a potential Etomidate Pneumocystis Jirovecii Pneumonia side effect(s) that can have serious consequences. A 60-year-old female patient (weight: NA) from CZ was diagnosed with the following symptoms/conditions: cushing^s syndrome and used Etomidate (dosage: NA) starting NS. After starting Etomidate the patient began experiencing various side effects, including: Pneumocystis Jirovecii Pneumonia, Sepsis, Off Label UseAdditional drugs used concurrently:
  • Ketoconazole
Although Etomidate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Pneumocystis Jirovecii Pneumonia, may still occur.
Etomidate Side Effect Report#8805978
Bradycardia, Cardiac Arrest
This Bradycardia problem was reported by a consumer or non-health professional from US. A 54-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Etomidate (dosage: NA). The following drugs were being taken at the same time:
  • Fentanyl
  • Succinylcholine Chloride
When using Etomidate, the patient experienced the following unwanted symptoms/side effects: Bradycardia, Cardiac ArrestAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Bradycardia, may become evident only after a product is in use by the general population.
Etomidate Side Effect Report#8790599
Maculopathy, Retinal Artery Occlusion, Hyperaemia, Scintillating Scotoma, Oedema, Visual Impairment, Tremor, Visual Field Defect, Infusion Related Reaction
This Maculopathy side effect was reported by a consumer or non-health professional from US. A 36-year-old female patient (weight:NA) experienced the following symptoms/conditions: wada test.The patient was prescribed Etomidate (drug dosage: NA), which was initiated on NS. Concurrently used drugs: NA..After starting to take Etomidate the consumer reported adverse symptoms, such as: Maculopathy, Retinal Artery Occlusion, Hyperaemia, Scintillating Scotoma, Oedema, Visual Impairment, Tremor, Visual Field Defect, Infusion Related ReactionThese side effects may potentially be related to Etomidate.
Etomidate Side Effect Report#8790492
Tremor, Eye Pain, Hyperaemia, Scintillating Scotoma, Macular Oedema, Retinal Artery Occlusion
This is a report of a 26-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: wada test, who was treated with Etomidate (dosage: NA, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Tremor, Eye Pain, Hyperaemia, Scintillating Scotoma, Macular Oedema, Retinal Artery Occlusion after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Etomidate treatment in female patients, resulting in Tremor side effect.
Etomidate Side Effect Report#8789720
Anaphylactic Reaction, Cardiopulmonary Failure, Arterial Haemorrhage, Cerebrovascular Accident
This report suggests a potential Etomidate Anaphylactic Reaction side effect(s) that can have serious consequences. A 19-year-old male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: NA and used Etomidate (dosage: NA) starting NS. After starting Etomidate the patient began experiencing various side effects, including: Anaphylactic Reaction, Cardiopulmonary Failure, Arterial Haemorrhage, Cerebrovascular AccidentAdditional drugs used concurrently: NA. Although Etomidate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Anaphylactic Reaction, may still occur.
Etomidate Side Effect Report#8390986-5
Atrial Fibrillation, Fatigue
This Atrial Fibrillation problem was reported by a physician from United States. A 80-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Feb 28, 2011 this consumer started treatment with Etomidate (dosage: NA). The following drugs were being taken at the same time:
  • Atenolol
  • Fentanyl
  • Ambien
  • Simvastatin
  • Rythmol
  • Zocor
  • Prilosec
  • Revlimid (5 Mg, Daily For 3 Weeks And Off 1 Week, Po)
When using Etomidate, the patient experienced the following unwanted symptoms/side effects: Atrial Fibrillation, FatigueThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Atrial Fibrillation, may become evident only after a product is in use by the general population.
Etomidate Side Effect Report#8363332-0
Blepharospasm, Amnesia, Tongue Disorder
This Blepharospasm side effect was reported by a pharmacist from United States. A 63-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Etomidate (drug dosage: NA), which was initiated on
Dec 21, 2009. Concurrently used drugs: NA..After starting to take Etomidate the consumer reported adverse symptoms, such as: Blepharospasm, Amnesia, Tongue DisorderThese side effects may potentially be related to Etomidate. The patient was hospitalized.
Etomidate Side Effect Report#8193055-2
Bradycardia, Cardiac Arrest
This is a report of a 47-year-old female patient (weight: NA) from United States, suffering from the following health symptoms/conditions: NA, who was treated with Etomidate (dosage: 14 Mg, start time: NS), combined with:
  • Succinylcholine Chloride (100 Mg, Single)
  • Fentanyl Citrate (100 Mcg Single)
and developed a serious reaction and side effect(s): Bradycardia, Cardiac Arrest after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Etomidate treatment in female patients, resulting in Bradycardia side effect.
Etomidate Side Effect Report#8193054-0
Bradycardia, Cardiac Arrest
This report suggests a potential Etomidate Bradycardia side effect(s) that can have serious consequences. A 54-year-old female patient (weight: NA) from United States was diagnosed with the following symptoms/conditions: anaesthesia and used Etomidate (dosage: 16 Mg, Single) starting NS. After starting Etomidate the patient began experiencing various side effects, including: Bradycardia, Cardiac ArrestAdditional drugs used concurrently:
  • Fentanyl Citrate (100 Mcg, Single)
  • Succinylcholine Chloride (120 Mg, Single)
Although Etomidate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Bradycardia, may still occur.
Etomidate Side Effect Report#8176175-8
Convulsion, Hypotension, Cardiac Failure, Bradycardia
This Convulsion problem was reported by a physician from Germany. A 37-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
May 31, 2011 this consumer started treatment with Etomidate (dosage: NA). The following drugs were being taken at the same time:
  • Eculizumab
  • Fentanyl
When using Etomidate, the patient experienced the following unwanted symptoms/side effects: Convulsion, Hypotension, Cardiac Failure, BradycardiaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Convulsion, may become evident only after a product is in use by the general population.
Etomidate Side Effect Report#8080999-5
Cardiac Failure, Convulsion
This Cardiac Failure side effect was reported by a physician from Germany. A 37-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Etomidate (drug dosage: NA), which was initiated on
May 31, 2011. Concurrently used drugs:
  • Eculizumab
  • Fentanyl
.After starting to take Etomidate the consumer reported adverse symptoms, such as: Cardiac Failure, ConvulsionThese side effects may potentially be related to Etomidate.
Etomidate Side Effect Report#7964305-X
Electrocardiogram St Segment Elevation
This is a report of a 42-year-old male patient (weight: NA) from United States, suffering from the following health symptoms/conditions: induction of anaesthesia, who was treated with Etomidate (dosage: 30 Mg X 1 Per Once, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Electrocardiogram St Segment Elevation after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Etomidate treatment in male patients, resulting in Electrocardiogram St Segment Elevation side effect.
Etomidate Side Effect Report#7960556-9
Osteonecrosis Of Jaw, Mitral Valve Incompetence, Blood Immunoglobulin G Decreased, Syncope, Peripheral Vascular Disorder, Intervertebral Disc Disorder, Dyspnoea, Mental Status Changes, Hyperglycaemia
This report suggests a potential Etomidate Osteonecrosis Of Jaw side effect(s) that can have serious consequences. A female patient (weight: NA) from United States was diagnosed with the following symptoms/conditions: NA and used Etomidate (dosage: 40 Mg, Unk) starting
May 01, 2005. After starting Etomidate the patient began experiencing various side effects, including: Osteonecrosis Of Jaw, Mitral Valve Incompetence, Blood Immunoglobulin G Decreased, Syncope, Peripheral Vascular Disorder, Intervertebral Disc Disorder, Dyspnoea, Mental Status Changes, HyperglycaemiaAdditional drugs used concurrently:
  • Neostigmine Methylsulfate (10 Mg, Unk)
  • Fentanyl Citrate (250 Ug, Unk)
  • Midazolam Hydrochloride (2 Mg, Unk)
  • Lasix (40 Mg, Prn)
  • Lortab
  • Oxycontin
  • Carvedilol (3.125 Mg, Bid)
  • Zosyn
The patient was hospitalized. Although Etomidate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Osteonecrosis Of Jaw, may still occur.
Etomidate Side Effect Report#7605545-9
Anaphylactic Reaction
This Anaphylactic Reaction problem was reported by a pharmacist from United States. A 63-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Mar 28, 2011 this consumer started treatment with Etomidate (dosage: NA). The following drugs were being taken at the same time: NA. When using Etomidate, the patient experienced the following unwanted symptoms/side effects: Anaphylactic ReactionAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Anaphylactic Reaction, may become evident only after a product is in use by the general population.
Etomidate Side Effect Report#7599595-9
Multi-organ Failure, Unevaluable Event, Renal Impairment, Anhedonia, Fear, Renal Injury, Anxiety, Pain, Renal Failure
This Multi-organ Failure side effect was reported by a consumer or non-health professional from United States. A 52-year-old male patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Etomidate (drug dosage: 8 Mg, Unk), which was initiated on
Jun 03, 2002. Concurrently used drugs:
  • Zinacef (1.5 G, Unk)
  • Solu-cortef (100 Mg, Unk)
  • Trasylol (25ml/hr Until Bottle Infused)
  • Fentanyl (500 ?g, Unk)
  • Succinylcholine Chloride (200 Mg, Unk)
  • Trasylol (1 Ml, Test Dose)
  • Protamine Sulfate (400 Mg, Unk)
  • Versed
.After starting to take Etomidate the consumer reported adverse symptoms, such as: Multi-organ Failure, Unevaluable Event, Renal Impairment, Anhedonia, Fear, Renal Injury, Anxiety, Pain, Renal FailureThese side effects may potentially be related to Etomidate.
Etomidate Side Effect Report#7591567-3
Pain, Mobility Decreased, Injury, Unevaluable Event, Cerebrovascular Accident, Renal Failure, Depression
This is a report of a 72-year-old male patient (weight: NA) from United States, suffering from the following health symptoms/conditions: NA, who was treated with Etomidate (dosage: Unk, start time:
Jan 20, 2006), combined with:
  • Pavulon (Unk)
  • Pepcid (20 Mg, Unk)
  • Trasylol (Unk)
  • Mannitol (25 G, Unk)
  • Ancef (Unk)
  • Crestor (40 Mg, Unk)
  • Acetylsalicylic Acid Srt (81 Mg, Unk)
  • Diovan (320 Mg, Unk)
and developed a serious reaction and side effect(s): Pain, Mobility Decreased, Injury, Unevaluable Event, Cerebrovascular Accident, Renal Failure, Depression after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Etomidate treatment in male patients, resulting in Pain side effect. The patient was hospitalized.
Etomidate Side Effect Report#7577126-7
Unevaluable Event, Pain, Renal Failure, Injury
This report suggests a potential Etomidate Unevaluable Event side effect(s) that can have serious consequences. A 71-year-old male patient (weight: NA) from United States was diagnosed with the following symptoms/conditions: NA and used Etomidate (dosage: 15 Mg, Unk) starting
Sep 23, 2005. After starting Etomidate the patient began experiencing various side effects, including: Unevaluable Event, Pain, Renal Failure, InjuryAdditional drugs used concurrently:
  • Propofol (Unk)
  • Lisinopril (40 Mg, Once)
  • Atenolol (100 Mg, Once)
  • Heparin (10 Ml, Unk)
  • Morphine (10 Mg, Unk)
  • Lasix (Unk)
  • Indocin
  • Fentanyl (5 Mg, Unk)
The patient was hospitalized. Although Etomidate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Unevaluable Event, may still occur.
Etomidate Side Effect Report#7504458-0
Renal Failure, Unevaluable Event, Injury, Pain, Anxiety, Anhedonia, Cerebrovascular Accident, Myocardial Infarction
This Renal Failure problem was reported by a consumer or non-health professional from United States. A 63-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Mar 26, 2002 this consumer started treatment with Etomidate (dosage: Unk). The following drugs were being taken at the same time:
  • Fentanyl (Unk)
  • Lidocaine (Unk)
  • Pancuronium Bromide (Unk)
  • Phenylephrine Hcl (Unk)
  • Albuterol Sulfate Autohaler (Unk)
  • Trasylol (Unk)
  • Hydrochlorothiazide (25 Mg, Unk)
  • Altace (5 Mg, Qd)
When using Etomidate, the patient experienced the following unwanted symptoms/side effects: Renal Failure, Unevaluable Event, Injury, Pain, Anxiety, Anhedonia, Cerebrovascular Accident, Myocardial InfarctionAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Renal Failure, may become evident only after a product is in use by the general population.
Etomidate Side Effect Report#7481037-5
Pain, Anxiety, Unevaluable Event, Fear, Cerebrovascular Accident, Renal Impairment, Cardiac Disorder, Organ Failure
This Pain side effect was reported by a consumer or non-health professional from United States. A 54-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Etomidate (drug dosage: Unk), which was initiated on
May 02, 2001. Concurrently used drugs:
  • Ancef (Unk)
  • Epinephrine (Micrograms/minute Titrated)
  • Tenormin (50 Mg, Qd)
  • Heparin (5000 Units)
  • Nitroglycerin (Micrograms/minute Titrated)
  • Trasylol (Unk)
  • Zaroxolyn (10 Mg, Qd)
  • Zocor (20 Mg @ Hour Of Sleep)
.After starting to take Etomidate the consumer reported adverse symptoms, such as: Pain, Anxiety, Unevaluable Event, Fear, Cerebrovascular Accident, Renal Impairment, Cardiac Disorder, Organ FailureThese side effects may potentially be related to Etomidate.
Etomidate Side Effect Report#7469594-6
Emotional Distress, Unevaluable Event, Injury, Mental Disorder, Renal Failure
This is a report of a 70-year-old male patient (weight: NA) from United States, suffering from the following health symptoms/conditions: NA, who was treated with Etomidate (dosage: 20 Mg, Unk, start time:
Jul 06, 2006), combined with:
  • Trasylol (200 Ml, Loading Dose)
  • Heparin (24,000 Units)
  • Epinephrine (Unk)
  • Mannitol (25 G, Unk)
  • Ephedrine Hydrate (Unk)
  • Amiodarone (Unk)
  • Trasylol (1 Ml, Unk)
  • Lisinopril (40 Mg, Qd)
and developed a serious reaction and side effect(s): Emotional Distress, Unevaluable Event, Injury, Mental Disorder, Renal Failure after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Etomidate treatment in male patients, resulting in Emotional Distress side effect.


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The appearance of Etomidate on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Etomidate reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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    Etomidate Safety Alerts, Active Ingredients, Usage Information

    NDC0069-0006
    TypeHUMAN PRESCRIPTION DRUG
    Proprietary NameEtomidate
    NameEtomidate
    Dosage FormINJECTION
    RouteINTRAVENOUS
    On market since20120203
    LabelerPfizer Laboratories Div Pfizer Inc.
    Active Ingredient(s)ETOMIDATE
    Strength(s)2
    Unit(s)mg/mL
    Pharma ClassGeneral Anesthesia [PE],General Anesthetic [EPC]

    More About Etomidate

    Side Effects reported to FDA: 68

    Etomidate safety alerts: 2013

    Reported deaths: 9

    Reported hospitalizations: 16

    Latest Etomidate clinical trials