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what is the treatment for too much body iron ;how can i get rid of it;?

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MOTRIN- OPTIC NEURITIS 2008-11-24 09:42:35

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Review Exjade Safety Reports submitted to FDA

Total Exjade reports: 791.
Exjade FDA safety alerts: 2007 .
Reported deaths: 220    Reported hospitalizations: 289.
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FDA Reported Exjade Side Effects: diarrhoea, blood creatinine increased, aspartate aminotransferase increased, alanine aminotransferase increased, blood bilirubin increased, asthenia, haemoglobin decreased, blood urea increased, abdominal pain upper, pyrexia, abdominal pain.
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Exjade Side Effects Report #5477740-9
Health Professional from UNITED STATES reported EXJADE problem on June 15, 2007. Female patient, child 11 years of age, weighting 158.7 lb, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: alopecia, trichorrhexis. EXJADE dosage: 20 MG/KG, QD, ORAL; 30 MG/KG. Patient recovered.

Exjade Side Effects Report #5477745-8
EXJADE problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 01, 2007. Male patient, 70 years of age, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: pruritus, rash. EXJADE dosage: unknown. During the same period patient was treated with REVLIMID. Patient recovered.

Exjade Side Effects Report #5477750-1
Consumer or non-health professional from UNITED STATES reported EXJADE problem on July 05, 2007. Female patient, 60 years of age, was diagnosed with myelodysplastic syndrome and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: anorexia, fatigue, pyrexia. EXJADE dosage: 1000 MG, QD, ORAL. During the same period patient was treated with ACETAMINOPHEN. Patient recovered.

Exjade Side Effects Report #5477754-9
EXJADE problem was reported by a Consumer or non-health professional from UNITED STATES on July 09, 2007. Male patient, 69 years of age, was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: abdominal distension, abdominal pain upper, diarrhoea. EXJADE dosage: unknown. Patient recovered.


Exjade Side Effects Report #5477755-0
Consumer or non-health professional from UNITED STATES reported EXJADE problem on July 30, 2007. Female patient, 52 years of age, was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: dizziness, headache, hyperhidrosis, pyrexia. EXJADE dosage: 750 MG, QD, ORAL. Patient recovered.

Exjade Side Effects Report #5477756-2
EXJADE problem was reported by a Pharmacist from UNITED STATES on July 19, 2007. Female patient, weighting 158.7 lb, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: chromaturia. EXJADE dosage: 625 MG/KG, QD, ORAL. Patient recovered.

Exjade Side Effects Report #5477759-8
Physician from UNITED STATES reported EXJADE problem on May 31, 2007. Female patient, 19 years of age, was diagnosed with haemochromatosis and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: herpes zoster, rash erythematous, urticaria. EXJADE dosage: 500 MG, ONCE/SINGLE, ORAL; 1000 MG, ONCE/SINGLE, ORAL; 1500 MG, QD, ORAL. During the same period patient was treated with MIRALAX, ACIDOPHILUS. Patient recovered.

Exjade Side Effects Report #5477760-4
EXJADE problem was reported by a Physician from UNITED STATES on May 08, 2007. Female patient, 35 years of age, weighting 145.5 lb, was diagnosed with haemosiderosis and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: abdominal pain, diarrhoea, nausea, vomiting. EXJADE dosage: 1500 MG, QD, ORAL. During the same period patient was treated with HYDROXYUREA, FOLIC ACID, PERCOCET, CONTRACEPTIVES NOS. Patient recovered.

Exjade Side Effects Report #5477762-8
Consumer or non-health professional from UNITED STATES reported EXJADE problem on May 25, 2007. Female patient, 73 years of age, weighting 112.9 lb, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: arthralgia, diarrhoea, fatigue, headache, muscle spasms, pain. EXJADE dosage: 1000 MG, QD, ORAL. Patient recovered.


Exjade Side Effects Report #5477763-X
EXJADE problem was reported by a Physician from UNITED STATES on May 22, 2007. Male patient, child 10 years of age, was diagnosed with sickle cell anaemia and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: abdominal pain, dysgeusia. EXJADE dosage: 500 MG, QD, ORAL; QD, ORAL. Patient recovered.

Exjade Side Effects Report #5375818-1
Consumer or non-health professional from UNITED STATES reported EXJADE problem on June 26, 2007. Female patient, 42 years of age, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: sickle cell anaemia, treatment noncompliance. EXJADE dosage: 1000 MG, QD. Patient died on 06/01/2007.

Exjade Side Effects Report #5375821-1
EXJADE problem was reported by a Physician from UNITED STATES on June 21, 2007. Female patient, 29 years of age, weighting 143.5 lb, was diagnosed with blood iron increased and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: abdominal pain, addison's disease, arthralgia, back pain, cellulitis, concomitant disease progression, constipation, dehydration, diarrhoea. EXJADE dosage: 1250 MG, QD. During the same period patient was treated with DESFERAL. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5375894-6
Physician from SPAIN reported EXJADE problem on June 20, 2007. Female patient, 55 years of age, was diagnosed with myelodysplastic syndrome and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: blood alkaline phosphatase increased, cholestasis, transaminases increased. EXJADE dosage: 20 MG/D. Patient recovered.

Exjade Side Effects Report #5376741-9
EXJADE problem was reported by a Health Professional from UNITED STATES on June 26, 2007. Male patient, 34 years of age, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: completed suicide, white blood cell count increased. EXJADE dosage: 1250 MG, QD. During the same period patient was treated with OXYCONTIN, OXYCODONE, PROTONIX, PROZAC, PHENERGAN, FOLIC ACID. Patient died on 06/14/2007.


Exjade Side Effects Report #5379721-2
Health Professional from UNITED STATES reported EXJADE problem on July 02, 2007. Female patient, 42 years of age, was diagnosed with haemochromatosis and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: sickle cell anaemia, treatment noncompliance. EXJADE dosage: 1000 MG, QD. During the same period patient was treated with FOLIC ACID, DILTIAZEM, DILANTIN, MS CONTIN, PROCRIT, TEMAZEPAM, VITAMIN D, DILAUDID. Patient died on 06/01/2007.

Exjade Side Effects Report #5381494-4
EXJADE problem was reported by a Pharmacist from UNITED STATES on July 05, 2007. Male patient, 76 years of age, weighting 149.9 lb, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: blood creatinine increased, hepatitis. EXJADE dosage: unknown. During the same period patient was treated with AVAPRO, ATENOLOL, PRAVACHOL, FOLIC ACID, VITAMIN B, ASPIRIN. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5381508-1
Health Professional from UNITED STATES reported EXJADE problem on June 26, 2007. Female patient, 80 years of age, weighting 134.9 lb, was diagnosed with blood iron increased, hypothyroidism, oedema, arteriosclerosis coronary artery and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, cardiac failure congestive, cholelithiasis, chromaturia, dyspnoea, escherichia sepsis, faeces pale, haemochromatosis, hepatitis. EXJADE dosage: 1250 MG, QD. During the same period patient was treated with SYNTHROID, LASIX, LOPRESSOR, FOSAMAX, VICODIN, CALCIUM CHLORIDE, RED BLOOD CELLS, LEVOTHYROXINE. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5381714-6
EXJADE problem was reported by a Physician from UNITED KINGDOM on June 29, 2007. Female patient, 19 years of age, was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: cardiac failure, treatment noncompliance. EXJADE dosage: unknown. During the same period patient was treated with DESFERAL. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5381718-3
Physician from UNITED STATES reported EXJADE problem on June 29, 2007. Male patient, 17 years of age, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: optic neuritis, renal tubular acidosis, scotoma. EXJADE dosage: 500 MG, QD. Patient recovered.


Exjade Side Effects Report #5383747-2
EXJADE problem was reported by a Physician from UNITED STATES on June 29, 2007. Female patient, 84 years of age, weighting 176.4 lb, was diagnosed with blood iron increased, urinary tract infection, cardiac failure congestive, hypertension and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: cardiomegaly, chest pain, costochondritis, dyspnoea, lung neoplasm. EXJADE dosage: 750 MG, QD. During the same period patient was treated with MACRODANTIN, LASIX, ENALAPRIL, ARANESP, NITRGLYCERIN TRANSDERMAL SYSTEM, SYNTHROID. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5385000-X
Physician from IRELAND reported EXJADE problem on July 03, 2007. Female patient, 30 years of age, was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: balance disorder, dizziness, gait disturbance, hypoacusis, nervous system disorder, tinnitus. EXJADE dosage: 30 MG/KG/D. During the same period patient was treated with ESOMEPRAZOLE MAGNESIUM. Patient recovered.

Exjade Side Effects Report #5385010-2
EXJADE problem was reported by a Consumer or non-health professional from UNITED STATES on July 06, 2007. Female patient, 39 years of age, was diagnosed with sickle cell anaemia and was treated with EXJADE. EXJADE dosage: 500 MG, QD. Patient died on 06/09/2007.

Exjade Side Effects Report #5385025-4
Physician from NETHERLANDS reported EXJADE problem on July 03, 2007. Female patient, child 10 years of age, was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: abdominal pain, splenomegaly. EXJADE dosage: 500 MG, QD (20 MG/KG/D). Patient recovered.

Exjade Side Effects Report #5387313-4
EXJADE problem was reported by a Physician from UNITED STATES on July 05, 2007. Male patient, 17 years of age, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: optic neuritis, renal tubular acidosis, scotoma. EXJADE dosage: 500 MG, QD. Patient recovered.

Exjade Side Effects Report #5388914-X
Consumer or non-health professional from UNITED STATES reported EXJADE problem on July 06, 2007. Male patient, 83 years of age, was diagnosed with haemochromatosis, myeloproliferative disorder and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: blood albumin decreased, blood bilirubin increased, blood creatinine increased, computerised tomogram abnormal, haematocrit decreased, haemoglobin decreased, nephrostomy, platelet count decreased, pyelonephritis. EXJADE dosage: 2000 MG, QD. During the same period patient was treated with PROCRIT, ATENOLOL, REMERON, IPRATROPIUM BROMIDE, NEUPOGEN. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5388946-1
EXJADE problem was reported by a Consumer or non-health professional from UNITED STATES on July 13, 2007. Female patient, 72 years of age, weighting 144.0 lb, was diagnosed with iron overload and was treated with EXJADE. EXJADE dosage: 1500 MG, QD. Patient died.

Exjade Side Effects Report #5388947-3
Consumer or non-health professional from UNITED STATES reported EXJADE problem on July 13, 2007. Male patient, 81 years of age, was diagnosed with myelodysplastic syndrome and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: cardiac failure congestive. EXJADE dosage: 1750 MG, QD. Patient died on 06/23/2007.

Exjade Side Effects Report #5389835-9
EXJADE problem was reported by a Pharmacist from NETHERLANDS on July 11, 2007. Male patient was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: nephrolithiasis, renal stone removal. EXJADE dosage: unknown. During the same period patient was treated with MORFINE, OMNIC, DOXYCYCLINE, TEMAZEPAM, TRISPORAL. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5391109-7
Physician from GREECE reported EXJADE problem on July 11, 2007. Female patient, 40 years of age, was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: biopsy skin abnormal, cutaneous vasculitis, purpura. EXJADE dosage: 500 MG, TID. During the same period patient was treated with LEXOTANIL, OCTALAM. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5391405-3
EXJADE problem was reported by a Physician from UNITED STATES on July 10, 2007. Female patient, 81 years of age, weighting 141.1 lb, was diagnosed with blood iron increased and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: acute prerenal failure, atelectasis, cardiac aneurysm, cardiac failure congestive, dialysis, dilatation atrial, dilatation ventricular, dyspnoea, ejection fraction decreased. EXJADE dosage: 1250 MG, QD. During the same period patient was treated with LASIX, LISINOPRIL, COUMADIN, MAGNESIUM OXIDE, POTASSIUM CHLORIDE, EPOGEN. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5391407-7
Consumer or non-health professional from UNITED STATES reported EXJADE problem on July 16, 2007. Female patient, 72 years of age, weighting 144.0 lb, was diagnosed with iron overload and was treated with EXJADE. EXJADE dosage: 1500 MG, QD. Patient died.

Exjade Side Effects Report #5391924-X
EXJADE problem was reported by a Physician from FRANCE on July 11, 2007. Female patient, 55 years of age, was diagnosed with myeloid leukaemia and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: eyelid oedema, visual acuity reduced, visual field defect. EXJADE dosage: 20 MG/KG, QD. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5393278-1
Physician from ARGENTINA reported EXJADE problem on July 11, 2007. Female patient, 14 years of age, was diagnosed with pulmonary haemosiderosis and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: encephalitis viral, life support, pseudomonas infection, pulmonary haemosiderosis, respiratory tract infection. EXJADE dosage: unknown. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5393297-5
EXJADE problem was reported by a Consumer or non-health professional from UNITED STATES on July 12, 2007. Female patient, 17 years of age, weighting 155.0 lb, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: caesarean section, normal newborn, pain, pre-eclampsia, pregnancy induced hypertension, sickle cell anaemia with crisis. EXJADE dosage: unknown. During the same period patient was treated with HYDROMORPHONE, METHADONE, FOLIC ACID, ALBUTEROL, REGLAN, ADVAIR DISKUS. Patient recovered.

Exjade Side Effects Report #5393320-8
Health Professional from UNITED STATES reported EXJADE problem on July 19, 2007. Female patient, 83 years of age, weighting 110.2 lb, was diagnosed with iron overload, myelodysplastic syndrome, hypertension and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: biopsy breast, infection, sepsis. EXJADE dosage: 125 MG, QD. During the same period patient was treated with REVLIMID, ALLOPURINOL, HYDROCHLOROTHIAZIDE, TENORMIN, FOLIC ACID. Patient was hospitalized. Patient died on 05/25/2007.

Exjade Side Effects Report #5393322-1
EXJADE problem was reported by a Physician from SINGAPORE on July 16, 2007. Male patient, 16 years of age, weighting 100.3 lb, was diagnosed with haemosiderosis, hypothyroidism, hypogonadism and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: chest pain, cold sweat, concomitant disease progression, congestive cardiomyopathy. EXJADE dosage: 1000 MG, QD. During the same period patient was treated with LEVOTHYROXINE, CALTRATE, TESTOSTERONE. Patient recovered.

Exjade Side Effects Report #5393344-0
Physician from UNITED STATES reported EXJADE problem on July 12, 2007. Male patient, 51 years of age, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: atrial flutter, bladder diverticulum, blood chloride decreased, blood creatinine increased, blood glucose increased, blood urea increased, haematocrit decreased, haematuria, hydronephrosis. EXJADE dosage: 1250 MG, QD. During the same period patient was treated with ACETYLSALICYLIC ACID SRT, FOLATE, FUROSEMIDE, TAMSULOSIN, PREDNISONE, COUMADIN. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5393373-7
EXJADE problem was reported by a Physician from UNITED STATES on July 19, 2007. Male patient, 87 years of age, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: myelodysplastic syndrome. EXJADE dosage: 1750 MG, QD. Patient died on 05/15/2007.

Exjade Side Effects Report #5393381-6
Physician from UNITED STATES reported EXJADE problem on July 13, 2007. Male patient, 17 years of age, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: optic neuritis, renal tubular acidosis, scotoma. EXJADE dosage: 500 MG, QD. During the same period patient was treated with FOLIC ACID, SYNTHROID, MIRALAX. Patient recovered.

Exjade Side Effects Report #5393383-X
EXJADE problem was reported by a Consumer or non-health professional from UNITED STATES on July 18, 2007. Male patient, 81 years of age, was diagnosed with myelodysplastic syndrome and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: cardiac failure congestive. EXJADE dosage: 1750 MG, QD. Patient died on 06/23/2007.

Exjade Side Effects Report #5394964-X
Physician from UNITED STATES reported EXJADE problem on July 16, 2007. Male patient, 23 years of age, weighting 116.8 lb, was diagnosed with iron overload, staphylococcal infection and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: blood creatinine increased, sickle cell anaemia with crisis. EXJADE dosage: 1000 MG, QD. During the same period patient was treated with VANCOMYCIN, ZOSYN. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5394965-1
EXJADE problem was reported by a Physician from ARGENTINA on July 17, 2007. Female patient, 14 years of age, was diagnosed with pulmonary haemosiderosis and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: acute tonsillitis, carbon monoxide diffusing capacity decreased, encephalitis viral, life support, pneumonia, pseudomonas infection, pulmonary haemosiderosis. EXJADE dosage: unknown. During the same period patient was treated with AZATHIOPRINE. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5394966-3
Physician from FRANCE reported EXJADE problem on July 18, 2007. Female patient, child 12 years of age, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: renal surgery, renal tubular disorder. EXJADE dosage: 500 MG/DAY. Patient recovered.

Exjade Side Effects Report #5394970-5
EXJADE problem was reported by a Physician from TURKEY on July 16, 2007. Male patient, child 4 years of age, weighting 39.68 lb, was diagnosed with serum ferritin increased and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: deafness. EXJADE dosage: 375 MG/D. Patient recovered.

Exjade Side Effects Report #5394983-3
Physician from UNITED STATES reported EXJADE problem on July 13, 2007. Female patient, 29 years of age, weighting 143.5 lb, was diagnosed with blood iron increased and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: abdominal pain, addison's disease, arthralgia, back pain, cellulitis, chest pain, concomitant disease progression, constipation, dehydration. EXJADE dosage: 1250 MG, QD. During the same period patient was treated with DESFERAL. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5396168-3
EXJADE problem was reported by a Physician from THAILAND on July 20, 2007. Female patient, weighting 57.32 lb, was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: angioedema. EXJADE dosage: 20 MG/KG/D. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5396208-1
Physician from UNITED STATES reported EXJADE problem on July 19, 2007. Male patient, 17 years of age, was diagnosed with iron overload, hypothyroidism, constipation and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: constipation, hypothyroidism, optic neuritis, renal tubular acidosis, scotoma. EXJADE dosage: 500 MG, QD. During the same period patient was treated with FOLIC ACID, SYNTHROID, MIRALAX. Patient recovered.

Exjade Side Effects Report #5398857-3
EXJADE problem was reported by a Health Professional from UNITED STATES on July 23, 2007. Male patient, child 10 years of age, weighting 60.19 lb, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase abnormal, blood bilirubin increased, blood creatinine decreased, blood glucose decreased, blood urea decreased, haematocrit decreased, haemoglobin decreased. EXJADE dosage: unknown. Patient recovered.

Exjade Side Effects Report #5398870-6
Health Professional from UNITED STATES reported EXJADE problem on July 23, 2007. Male patient, 15 years of age, weighting 49.19 lb, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: haematocrit decreased, haemoglobin decreased, haemoglobin s increased, hypertension, laboratory test abnormal, lymphocyte count increased, neutrophil count increased, red blood cell count decreased, treatment noncompliance. EXJADE dosage: 1250MG, QD. Patient recovered.

Exjade Side Effects Report #5399847-7
EXJADE problem was reported by a Health Professional from UNITED STATES on July 25, 2007. Female patient, 17 years of age, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: staphylococcal infection, vomiting. EXJADE dosage: unknown. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5399849-0
Health Professional from UNITED STATES reported EXJADE problem on July 19, 2007. Female patient, 80 years of age, weighting 134.9 lb, was diagnosed with blood iron increased, hypothyroidism, oedema, arteriosclerosis coronary artery and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, cardiac failure congestive, cholelithiasis, chromaturia, dyspnoea, escherichia sepsis, faeces pale, haemochromatosis, hepatitis. EXJADE dosage: 1250 MG, QD. During the same period patient was treated with SYNTHROID, LASIX, LOPRESSOR, FOSAMAX, VICODIN, CALCIUM CHLORIDE, RED BLOOD CELLS, LEVOTHYROXINE. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5400557-8
EXJADE problem was reported by a Health Professional from UNITED STATES on July 27, 2007. Male patient, 93 years of age, was treated with EXJADE. EXJADE dosage: unknown. Patient died.

Exjade Side Effects Report #5400560-8
Physician from UNITED STATES reported EXJADE problem on July 27, 2007. Male patient, 65 years of age, was diagnosed with iron overload, acute myeloid leukaemia and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: acute myeloid leukaemia, acute myeloid leukaemia recurrent, atelectasis, blood albumin decreased, blood alkaline phosphatase increased, blood creatinine increased, blood sodium decreased, bronchoscopy normal, cardiac disorder. EXJADE dosage: 1750 MG, QD. During the same period patient was treated with RED BLOOD CELLS, PLATELETS, NEUPOGEN, LAMIVUDINE, ACYCLOVIR, METOPROLOL SUCCINATE, NORVASC, DILTIAZEM. Patient was hospitalized. Patient died on 06/10/2007.

Exjade Side Effects Report #5401104-7
EXJADE problem was reported by a Physician from UNITED STATES on July 26, 2007. Male patient, child 7 years of age, weighting 41.67 lb, was diagnosed with iron overload, chest pain, splenectomy and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased. EXJADE dosage: 500 MG, QD. During the same period patient was treated with HYDROXYUREA, PENICILLIN V POTASSIUM. Patient recovered.

Exjade Side Effects Report #5375818-1
Consumer or non-health professional from UNITED STATES reported EXJADE problem on June 26, 2007. Female patient, 42 years of age, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: sickle cell anaemia, treatment noncompliance. EXJADE dosage: 1000 MG, QD. Patient died on 06/01/2007.

Exjade Side Effects Report #5375821-1
EXJADE problem was reported by a Physician from UNITED STATES on June 21, 2007. Female patient, 29 years of age, weighting 143.5 lb, was diagnosed with blood iron increased and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: abdominal pain, addison's disease, arthralgia, back pain, cellulitis, concomitant disease progression, constipation, dehydration, diarrhoea. EXJADE dosage: 1250 MG, QD. During the same period patient was treated with DESFERAL. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5375894-6
Physician from SPAIN reported EXJADE problem on June 20, 2007. Female patient, 55 years of age, was diagnosed with myelodysplastic syndrome and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: blood alkaline phosphatase increased, cholestasis, transaminases increased. EXJADE dosage: 20 MG/D. Patient recovered.

Exjade Side Effects Report #5376741-9
EXJADE problem was reported by a Health Professional from UNITED STATES on June 26, 2007. Male patient, 34 years of age, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: completed suicide, white blood cell count increased. EXJADE dosage: 1250 MG, QD. During the same period patient was treated with OXYCONTIN, OXYCODONE, PROTONIX, PROZAC, PHENERGAN, FOLIC ACID. Patient died on 06/14/2007.

Exjade Side Effects Report #5379721-2
Health Professional from UNITED STATES reported EXJADE problem on July 02, 2007. Female patient, 42 years of age, was diagnosed with haemochromatosis and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: sickle cell anaemia, treatment noncompliance. EXJADE dosage: 1000 MG, QD. During the same period patient was treated with FOLIC ACID, DILTIAZEM, DILANTIN, MS CONTIN, PROCRIT, TEMAZEPAM, VITAMIN D, DILAUDID. Patient died on 06/01/2007.

Exjade Side Effects Report #5381494-4
EXJADE problem was reported by a Pharmacist from UNITED STATES on July 05, 2007. Male patient, 76 years of age, weighting 149.9 lb, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: blood creatinine increased, hepatitis. EXJADE dosage: unknown. During the same period patient was treated with AVAPRO, ATENOLOL, PRAVACHOL, FOLIC ACID, VITAMIN B, ASPIRIN. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5381508-1
Health Professional from UNITED STATES reported EXJADE problem on June 26, 2007. Female patient, 80 years of age, weighting 134.9 lb, was diagnosed with blood iron increased, hypothyroidism, oedema, arteriosclerosis coronary artery and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, cardiac failure congestive, cholelithiasis, chromaturia, dyspnoea, escherichia sepsis, faeces pale, haemochromatosis, hepatitis. EXJADE dosage: 1250 MG, QD. During the same period patient was treated with SYNTHROID, LASIX, LOPRESSOR, FOSAMAX, VICODIN, CALCIUM CHLORIDE, RED BLOOD CELLS, LEVOTHYROXINE. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5381714-6
EXJADE problem was reported by a Physician from UNITED KINGDOM on June 29, 2007. Female patient, 19 years of age, was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: cardiac failure, treatment noncompliance. EXJADE dosage: unknown. During the same period patient was treated with DESFERAL. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5381718-3
Physician from UNITED STATES reported EXJADE problem on June 29, 2007. Male patient, 17 years of age, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: optic neuritis, renal tubular acidosis, scotoma. EXJADE dosage: 500 MG, QD. Patient recovered.

Exjade Side Effects Report #5383747-2
EXJADE problem was reported by a Physician from UNITED STATES on June 29, 2007. Female patient, 84 years of age, weighting 176.4 lb, was diagnosed with blood iron increased, urinary tract infection, cardiac failure congestive, hypertension and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: cardiomegaly, chest pain, costochondritis, dyspnoea, lung neoplasm. EXJADE dosage: 750 MG, QD. During the same period patient was treated with MACRODANTIN, LASIX, ENALAPRIL, ARANESP, NITRGLYCERIN TRANSDERMAL SYSTEM, SYNTHROID. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5385000-X
Physician from IRELAND reported EXJADE problem on July 03, 2007. Female patient, 30 years of age, was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: balance disorder, dizziness, gait disturbance, hypoacusis, nervous system disorder, tinnitus. EXJADE dosage: 30 MG/KG/D. During the same period patient was treated with ESOMEPRAZOLE MAGNESIUM. Patient recovered.

Exjade Side Effects Report #5385010-2
EXJADE problem was reported by a Consumer or non-health professional from UNITED STATES on July 06, 2007. Female patient, 39 years of age, was diagnosed with sickle cell anaemia and was treated with EXJADE. EXJADE dosage: 500 MG, QD. Patient died on 06/09/2007.

Exjade Side Effects Report #5385025-4
Physician from NETHERLANDS reported EXJADE problem on July 03, 2007. Female patient, child 10 years of age, was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: abdominal pain, splenomegaly. EXJADE dosage: 500 MG, QD (20 MG/KG/D). Patient recovered.

Exjade Side Effects Report #5387313-4
EXJADE problem was reported by a Physician from UNITED STATES on July 05, 2007. Male patient, 17 years of age, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: optic neuritis, renal tubular acidosis, scotoma. EXJADE dosage: 500 MG, QD. Patient recovered.

Exjade Side Effects Report #5388914-X
Consumer or non-health professional from UNITED STATES reported EXJADE problem on July 06, 2007. Male patient, 83 years of age, was diagnosed with haemochromatosis, myeloproliferative disorder and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: blood albumin decreased, blood bilirubin increased, blood creatinine increased, computerised tomogram abnormal, haematocrit decreased, haemoglobin decreased, nephrostomy, platelet count decreased, pyelonephritis. EXJADE dosage: 2000 MG, QD. During the same period patient was treated with PROCRIT, ATENOLOL, REMERON, IPRATROPIUM BROMIDE, NEUPOGEN. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5388946-1
EXJADE problem was reported by a Consumer or non-health professional from UNITED STATES on July 13, 2007. Female patient, 72 years of age, weighting 144.0 lb, was diagnosed with iron overload and was treated with EXJADE. EXJADE dosage: 1500 MG, QD. Patient died.

Exjade Side Effects Report #5388947-3
Consumer or non-health professional from UNITED STATES reported EXJADE problem on July 13, 2007. Male patient, 81 years of age, was diagnosed with myelodysplastic syndrome and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: cardiac failure congestive. EXJADE dosage: 1750 MG, QD. Patient died on 06/23/2007.

Exjade Side Effects Report #5389835-9
EXJADE problem was reported by a Pharmacist from NETHERLANDS on July 11, 2007. Male patient was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: nephrolithiasis, renal stone removal. EXJADE dosage: unknown. During the same period patient was treated with MORFINE, OMNIC, DOXYCYCLINE, TEMAZEPAM, TRISPORAL. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5391109-7
Physician from GREECE reported EXJADE problem on July 11, 2007. Female patient, 40 years of age, was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: biopsy skin abnormal, cutaneous vasculitis, purpura. EXJADE dosage: 500 MG, TID. During the same period patient was treated with LEXOTANIL, OCTALAM. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5391405-3
EXJADE problem was reported by a Physician from UNITED STATES on July 10, 2007. Female patient, 81 years of age, weighting 141.1 lb, was diagnosed with blood iron increased and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: acute prerenal failure, atelectasis, cardiac aneurysm, cardiac failure congestive, dialysis, dilatation atrial, dilatation ventricular, dyspnoea, ejection fraction decreased. EXJADE dosage: 1250 MG, QD. During the same period patient was treated with LASIX, LISINOPRIL, COUMADIN, MAGNESIUM OXIDE, POTASSIUM CHLORIDE, EPOGEN. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5391407-7
Consumer or non-health professional from UNITED STATES reported EXJADE problem on July 16, 2007. Female patient, 72 years of age, weighting 144.0 lb, was diagnosed with iron overload and was treated with EXJADE. EXJADE dosage: 1500 MG, QD. Patient died.

Exjade Side Effects Report #5391924-X
EXJADE problem was reported by a Physician from FRANCE on July 11, 2007. Female patient, 55 years of age, was diagnosed with myeloid leukaemia and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: eyelid oedema, visual acuity reduced, visual field defect. EXJADE dosage: 20 MG/KG, QD. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5393278-1
Physician from ARGENTINA reported EXJADE problem on July 11, 2007. Female patient, 14 years of age, was diagnosed with pulmonary haemosiderosis and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: encephalitis viral, life support, pseudomonas infection, pulmonary haemosiderosis, respiratory tract infection. EXJADE dosage: unknown. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5393297-5
EXJADE problem was reported by a Consumer or non-health professional from UNITED STATES on July 12, 2007. Female patient, 17 years of age, weighting 155.0 lb, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: caesarean section, normal newborn, pain, pre-eclampsia, pregnancy induced hypertension, sickle cell anaemia with crisis. EXJADE dosage: unknown. During the same period patient was treated with HYDROMORPHONE, METHADONE, FOLIC ACID, ALBUTEROL, REGLAN, ADVAIR DISKUS. Patient recovered.

Exjade Side Effects Report #5393320-8
Health Professional from UNITED STATES reported EXJADE problem on July 19, 2007. Female patient, 83 years of age, weighting 110.2 lb, was diagnosed with iron overload, myelodysplastic syndrome, hypertension and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: biopsy breast, infection, sepsis. EXJADE dosage: 125 MG, QD. During the same period patient was treated with REVLIMID, ALLOPURINOL, HYDROCHLOROTHIAZIDE, TENORMIN, FOLIC ACID. Patient was hospitalized. Patient died on 05/25/2007.

Exjade Side Effects Report #5393322-1
EXJADE problem was reported by a Physician from SINGAPORE on July 16, 2007. Male patient, 16 years of age, weighting 100.3 lb, was diagnosed with haemosiderosis, hypothyroidism, hypogonadism and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: chest pain, cold sweat, concomitant disease progression, congestive cardiomyopathy. EXJADE dosage: 1000 MG, QD. During the same period patient was treated with LEVOTHYROXINE, CALTRATE, TESTOSTERONE. Patient recovered.

Exjade Side Effects Report #5393344-0
Physician from UNITED STATES reported EXJADE problem on July 12, 2007. Male patient, 51 years of age, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: atrial flutter, bladder diverticulum, blood chloride decreased, blood creatinine increased, blood glucose increased, blood urea increased, haematocrit decreased, haematuria, hydronephrosis. EXJADE dosage: 1250 MG, QD. During the same period patient was treated with ACETYLSALICYLIC ACID SRT, FOLATE, FUROSEMIDE, TAMSULOSIN, PREDNISONE, COUMADIN. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5393373-7
EXJADE problem was reported by a Physician from UNITED STATES on July 19, 2007. Male patient, 87 years of age, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: myelodysplastic syndrome. EXJADE dosage: 1750 MG, QD. Patient died on 05/15/2007.

Exjade Side Effects Report #5393381-6
Physician from UNITED STATES reported EXJADE problem on July 13, 2007. Male patient, 17 years of age, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: optic neuritis, renal tubular acidosis, scotoma. EXJADE dosage: 500 MG, QD. During the same period patient was treated with FOLIC ACID, SYNTHROID, MIRALAX. Patient recovered.

Exjade Side Effects Report #5393383-X
EXJADE problem was reported by a Consumer or non-health professional from UNITED STATES on July 18, 2007. Male patient, 81 years of age, was diagnosed with myelodysplastic syndrome and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: cardiac failure congestive. EXJADE dosage: 1750 MG, QD. Patient died on 06/23/2007.

Exjade Side Effects Report #5394964-X
Physician from UNITED STATES reported EXJADE problem on July 16, 2007. Male patient, 23 years of age, weighting 116.8 lb, was diagnosed with iron overload, staphylococcal infection and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: blood creatinine increased, sickle cell anaemia with crisis. EXJADE dosage: 1000 MG, QD. During the same period patient was treated with VANCOMYCIN, ZOSYN. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5394965-1
EXJADE problem was reported by a Physician from ARGENTINA on July 17, 2007. Female patient, 14 years of age, was diagnosed with pulmonary haemosiderosis and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: acute tonsillitis, carbon monoxide diffusing capacity decreased, encephalitis viral, life support, pneumonia, pseudomonas infection, pulmonary haemosiderosis. EXJADE dosage: unknown. During the same period patient was treated with AZATHIOPRINE. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5394966-3
Physician from FRANCE reported EXJADE problem on July 18, 2007. Female patient, child 12 years of age, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: renal surgery, renal tubular disorder. EXJADE dosage: 500 MG/DAY. Patient recovered.

Exjade Side Effects Report #5394970-5
EXJADE problem was reported by a Physician from TURKEY on July 16, 2007. Male patient, child 4 years of age, weighting 39.68 lb, was diagnosed with serum ferritin increased and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: deafness. EXJADE dosage: 375 MG/D. Patient recovered.

Exjade Side Effects Report #5394983-3
Physician from UNITED STATES reported EXJADE problem on July 13, 2007. Female patient, 29 years of age, weighting 143.5 lb, was diagnosed with blood iron increased and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: abdominal pain, addison's disease, arthralgia, back pain, cellulitis, chest pain, concomitant disease progression, constipation, dehydration. EXJADE dosage: 1250 MG, QD. During the same period patient was treated with DESFERAL. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5396168-3
EXJADE problem was reported by a Physician from THAILAND on July 20, 2007. Female patient, weighting 57.32 lb, was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: angioedema. EXJADE dosage: 20 MG/KG/D. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5396208-1
Physician from UNITED STATES reported EXJADE problem on July 19, 2007. Male patient, 17 years of age, was diagnosed with iron overload, hypothyroidism, constipation and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: constipation, hypothyroidism, optic neuritis, renal tubular acidosis, scotoma. EXJADE dosage: 500 MG, QD. During the same period patient was treated with FOLIC ACID, SYNTHROID, MIRALAX. Patient recovered.

Exjade Side Effects Report #5398857-3
EXJADE problem was reported by a Health Professional from UNITED STATES on July 23, 2007. Male patient, child 10 years of age, weighting 60.19 lb, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase abnormal, blood bilirubin increased, blood creatinine decreased, blood glucose decreased, blood urea decreased, haematocrit decreased, haemoglobin decreased. EXJADE dosage: unknown. Patient recovered.

Exjade Side Effects Report #5398870-6
Health Professional from UNITED STATES reported EXJADE problem on July 23, 2007. Male patient, 15 years of age, weighting 49.19 lb, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: haematocrit decreased, haemoglobin decreased, haemoglobin s increased, hypertension, laboratory test abnormal, lymphocyte count increased, neutrophil count increased, red blood cell count decreased, treatment noncompliance. EXJADE dosage: 1250MG, QD. Patient recovered.

Exjade Side Effects Report #5399847-7
EXJADE problem was reported by a Health Professional from UNITED STATES on July 25, 2007. Female patient, 17 years of age, was diagnosed with iron overload and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: staphylococcal infection, vomiting. EXJADE dosage: unknown. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5399849-0
Health Professional from UNITED STATES reported EXJADE problem on July 19, 2007. Female patient, 80 years of age, weighting 134.9 lb, was diagnosed with blood iron increased, hypothyroidism, oedema, arteriosclerosis coronary artery and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, cardiac failure congestive, cholelithiasis, chromaturia, dyspnoea, escherichia sepsis, faeces pale, haemochromatosis, hepatitis. EXJADE dosage: 1250 MG, QD. During the same period patient was treated with SYNTHROID, LASIX, LOPRESSOR, FOSAMAX, VICODIN, CALCIUM CHLORIDE, RED BLOOD CELLS, LEVOTHYROXINE. Patient was hospitalized. Patient recovered.

Exjade Side Effects Report #5400557-8
EXJADE problem was reported by a Health Professional from UNITED STATES on July 27, 2007. Male patient, 93 years of age, was treated with EXJADE. EXJADE dosage: unknown. Patient died.

Exjade Side Effects Report #5400560-8
Physician from UNITED STATES reported EXJADE problem on July 27, 2007. Male patient, 65 years of age, was diagnosed with iron overload, acute myeloid leukaemia and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: acute myeloid leukaemia, acute myeloid leukaemia recurrent, atelectasis, blood albumin decreased, blood alkaline phosphatase increased, blood creatinine increased, blood sodium decreased, bronchoscopy normal, cardiac disorder. EXJADE dosage: 1750 MG, QD. During the same period patient was treated with RED BLOOD CELLS, PLATELETS, NEUPOGEN, LAMIVUDINE, ACYCLOVIR, METOPROLOL SUCCINATE, NORVASC, DILTIAZEM. Patient was hospitalized. Patient died on 06/10/2007.

Exjade Side Effects Report #5401104-7
EXJADE problem was reported by a Physician from UNITED STATES on July 26, 2007. Male patient, child 7 years of age, weighting 41.67 lb, was diagnosed with iron overload, chest pain, splenectomy and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased. EXJADE dosage: 500 MG, QD. During the same period patient was treated with HYDROXYUREA, PENICILLIN V POTASSIUM. Patient recovered.

Exjade Side Effects Report #5756038-5
Consumer or non-health professional from UNITED STATES reported EXJADE problem on May 28, 2008. Male patient, weighting 101.0 lb, was diagnosed with iron overload and was treated with EXJADE. EXJADE dosage: 1750 MG, QD. During the same period patient was treated with BLOOD TRANSFUSION. Patient died on 03/25/2008.

Exjade Side Effects Report #5756053-1
EXJADE problem was reported by a Physician from UNITED STATES on May 27, 2008. Female patient was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: skin necrosis, toxic epidermal necrolysis. EXJADE dosage: 20 MG/KG. Patient recovered.

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