HOLOXAN Side Effects

5885845-3 | Dehydration, Febrile Bone Marrow Aplasia, Pneumonia Aspiration, Renal Impairment, Septic Shock, Vomiting
on Sep 09, 2008 Male patient from UNITED STATES , 33 years of age, was diagnosed with germ cell cancer and was treated with Holoxan (View Usage). Patient experienced the following unwanted or unexpected effects: dehydration, febrile bone marrow aplasia, pneumonia aspiration, renal impairment, septic shock, vomiting. Holoxan dosage: 2340mg Total Daily Dose From 04aug08 (day1) To 08aug08 (day5).. During the same period patient was treated with CISPLATYL (39mg Total Daily Dose From 04aug08 (day1) To 08aug08 (day5).) (View Cisplatyl Review and Cisplatyl Label ), GEMZAR (1950mg Total Daily Dose Administered From 04aug08 (day1) To 08aug08 (day5).) (View Gemzar Review and Gemzar Label ). Patient was hospitalized.

5884632-X | Dehydration, Febrile Bone Marrow Aplasia, Renal Impairment, Septic Shock, Vomiting
Patient was taking Holoxan (View Usage). Patient had the following side effects: dehydration, febrile bone marrow aplasia, renal impairment, septic shock, vomiting on Sep 05, 2008 from UNITED STATES Additional patient health information: Male patient , 33 years of age, was diagnosed with germ cell cancer and. Holoxan dosage: 2340mg Total Daily Dose From 04aug08 (day1) To 08aug08 (day5).. During the same period patient was treated with CISPLATYL (39mg Total Daily Dose From 04aug08 (day1) To 08aug08 (day5).) (View Cisplatyl Review and Cisplatyl Label ), GEMZAR (1950mg Total Daily Dose Administered From 04aug08 (day1) To 08aug08 (day5).) (View Gemzar Review and Gemzar Label ). Patient was hospitalized.

5883793-6 | Anaemia, Pneumothorax
Adverse event was reported on Sep 08, 2008 by a Male patient taking Holoxan (View Usage) (Dosage: ) was diagnosed with ewing's sarcoma and. Location: FRANCE , 48 years of age, After Holoxan was administered, patient had the following side effects: anaemia, pneumothorax. During the same period patient was treated with ETOPOSIDE (View Etoposide Review and Etoposide Label ), NEUPOGEN (View Neupogen Review and Neupogen Label ). Patient was hospitalized.

5870510-9 | Dehydration, Febrile Bone Marrow Aplasia, Renal Impairment, Septic Shock, Vomiting
on Aug 27, 2008 Male patient from UNITED STATES , 33 years of age, was diagnosed with germ cell cancer and was treated with Holoxan (View Usage). Patient experienced the following unwanted or unexpected effects: dehydration, febrile bone marrow aplasia, renal impairment, septic shock, vomiting. Holoxan dosage: 2340mg Total Daily Dose From Day 1 To Day 5.. During the same period patient was treated with CISPLATYL (39mg Total Daily Dose From Day 1 To Day 5.) (View Cisplatyl Review and Cisplatyl Label ), GEMZAR (1950mg Total Daily Dose Administered On 04aug08 (day1) And On 08aug08 (day5).) (View Gemzar Review and Gemzar Label ). Patient was hospitalized.


5851430-2 | Anaemia, Pneumothorax
on Aug 11, 2008 Male patient from UNITED STATES , 48 years of age, was diagnosed with ewing's sarcoma and was treated with Holoxan (View Usage). Patient had the following side effects: anaemia, pneumothorax. Holoxan dosage: . During the same period patient was treated with ETOPOSIDE (View Etoposide Review and Etoposide Label ), NEUPOGEN (View Neupogen Review and Neupogen Label ). Patient was hospitalized.

5836274-X | Cystitis Haemorrhagic
Patient was taking Holoxan (View Usage). After Holoxan was administered, patient had the following side effects: cystitis haemorrhagic on Jul 28, 2008 from UNITED STATES Additional patient health information: Male patient , 70 years of age, . Holoxan dosage: . During the same period patient was treated with MESNA (1 Dosage Form = 3 G/m2.) (View Mesna Review and Mesna Label ).

5820238-6 | Haemolysis, Liver Function Test Abnormal, Pyrexia, Thrombocytopenia
Adverse event was reported on Jul 14, 2008 by a Male patient taking Holoxan (View Usage) (Dosage: ) . Location: UNITED STATES , 71 years of age, Patient experienced the following unwanted or unexpected effects: haemolysis, liver function test abnormal, pyrexia, thrombocytopenia. During the same period patient was treated with EPIRUBICIN (View Epirubicin Review and Epirubicin Label ).

5813332-7 | Encephalopathy, Malignant Neoplasm Progression
on Jul 08, 2008 Female patient from FRANCE , 47 years of age, was diagnosed with ovarian cancer and was treated with Holoxan (View Usage). Patient had the following side effects: encephalopathy, malignant neoplasm progression. Holoxan dosage: . During the same period patient was treated with UROMITEXAN (View Uromitexan Review and Uromitexan Label ), VEPESID (View Vepesid Review and Vepesid Label ). Patient was hospitalized.

5711586-9 | Electroencephalogram Abnormal, Somnolence
on Apr 11, 2008 Female patient from UNITED STATES , 25 years of age, was treated with Holoxan (View Usage). After Holoxan was administered, patient had the following side effects: electroencephalogram abnormal, somnolence. Holoxan dosage: 1 Dosage Form=3g/m2..

5708226-1 | Abdominal Pain, Accidental Exposure, Headache, Nausea
Patient was taking Holoxan (View Usage). Patient experienced the following unwanted or unexpected effects: abdominal pain (What is abdominal pain?), accidental exposure, headache (What is headache?), nausea (What is nausea?) on Apr 08, 2008 from UNITED STATES Additional patient health information: Female patient , 33 years of age, . Holoxan dosage: .

5705408-X | Encephalopathy
Adverse event was reported on Apr 04, 2008 by a Female patient taking Holoxan (View Usage) (Dosage: ) . Location: UNITED STATES , 47 years of age, Patient had the following side effects: encephalopathy. During the same period patient was treated with ETOPOSIDE (View Etoposide Review and Etoposide Label ). Patient was hospitalized.

5683025-8 | Aphasia, Coma, Neurotoxicity, Toxic Encephalopathy
on Mar 19, 2008 Female patient from GERMANY , 56 years of age, was diagnosed with multiple myeloma (What is multiple myeloma?), gastritis prophylaxis and was treated with Holoxan (View Usage). After Holoxan was administered, patient had the following side effects: aphasia (What is aphasia?), coma, neurotoxicity, toxic encephalopathy. Holoxan dosage: . During the same period patient was treated with ETOPOSIDE (View Etoposide Review and Etoposide Label ), EPIRUBICIN (View Epirubicin Review and Epirubicin Label ), UROMITEXAN (View Uromitexan Review and Uromitexan Label ), PANTOZOL (View Pantozol Review and Pantozol Label ). Patient was hospitalized.

5673137-7 | Anaemia, Brain Abscess, Facial Palsy, Myoclonus, Partial Seizures
on Mar 11, 2008 Male patient from UNITED STATES , 41 years of age, was diagnosed with germ cell cancer and was treated with Holoxan (View Usage). Patient experienced the following unwanted or unexpected effects: anaemia, brain abscess, facial palsy, myoclonus, partial seizures. Holoxan dosage: . During the same period patient was treated with GEMZAR (Initial Administration: 11-jan-2008) (View Gemzar Review and Gemzar Label ), CISPLATYL (View Cisplatyl Review and Cisplatyl Label ). Patient was hospitalized.

5671274-4 | Anaemia, Brain Abscess, Facial Palsy, Myoclonus, Partial Seizures
Patient was taking Holoxan (View Usage). Patient had the following side effects: anaemia, brain abscess, facial palsy, myoclonus, partial seizures on Mar 06, 2008 from UNITED STATES Additional patient health information: Male patient , 41 years of age, was diagnosed with germ cell cancer and. Holoxan dosage: . During the same period patient was treated with GEMZAR (View Gemzar Review and Gemzar Label ), CISPLATYL (View Cisplatyl Review and Cisplatyl Label ). Patient was hospitalized.

5644338-9 | Anaemia, Brain Abscess, Facial Palsy, Myoclonus, Partial Seizures
Adverse event was reported on Feb 18, 2008 by a Male patient taking Holoxan (View Usage) (Dosage: ) was diagnosed with germ cell cancer and. Location: UNITED STATES , 41 years of age, After Holoxan was administered, patient had the following side effects: anaemia, brain abscess, facial palsy, myoclonus, partial seizures. During the same period patient was treated with GEMZAR (View Gemzar Review and Gemzar Label ), CISPLATYL (View Cisplatyl Review and Cisplatyl Label ). Patient was hospitalized.

5636291-9 | Anal Inflammation, Coma, Encephalitis, Febrile Bone Marrow Aplasia, Hypotension, Multi-organ Failure, Vomiting
on Feb 13, 2008 Male patient from UNITED STATES , child 11 years of age, was diagnosed with chondrosarcoma, metastases to lung and was treated with Holoxan (View Usage). Patient experienced the following unwanted or unexpected effects: anal inflammation, coma, encephalitis (What is encephalitis?), febrile bone marrow aplasia, hypotension, multi-organ failure, vomiting. Holoxan dosage: . During the same period patient was treated with ADRIAMYCIN PFS (View Adriamycin Pfs Review and Adriamycin Pfs Label ), UROMITEXAN (View Uromitexan Review and Uromitexan Label ). Patient was hospitalized.

5599688-1 | Arthritis Bacterial, Neutropenia
on Jan 14, 2008 Female patient from UNITED STATES , 54 years of age, was diagnosed with arthritis bacterial and was treated with Holoxan (View Usage). Patient had the following side effects: arthritis bacterial, neutropenia. Holoxan dosage: . During the same period patient was treated with VEPESID (View Vepesid Review and Vepesid Label ), UROMITEXAN (View Uromitexan Review and Uromitexan Label ), ALPRAZOLAM (View Alprazolam Review and Alprazolam Label ), ZOLPIDEM (View Zolpidem Review and Zolpidem Label ), MAALOX (View Maalox Review and Maalox Label ), ESOMEPRAZOLE (View Esomeprazole Review and Esomeprazole Label ), DALACIN (View Dalacin Review and Dalacin Label ), RIFAMPICIN (View Rifampicin Review and Rifampicin Label ). Patient was hospitalized.

5599668-6 | Aplasia, Apraxia, Mucosal Inflammation, Multi-organ Failure, Walking Disability
Patient was taking Holoxan (View Usage). After Holoxan was administered, patient had the following side effects: aplasia, apraxia, mucosal inflammation, multi-organ failure, walking disability on Jan 11, 2008 from UNITED STATES Additional patient health information: Male patient , child 11 years of age, was diagnosed with chondrosarcoma and. Holoxan dosage: . During the same period patient was treated with ADRIAMYCIN PFS (View Adriamycin Pfs Review and Adriamycin Pfs Label ), UROMITEXAN (View Uromitexan Review and Uromitexan Label ).

5585439-3 | Asthenia, Coma, Cough, Disease Progression, Dyspnoea, Encephalopathy, Febrile Bone Marrow Aplasia, Hallucination
Adverse event was reported on Nov 23, 2007 by a Female patient taking Holoxan (View Usage) (Dosage: ) was diagnosed with uterine cancer (What is uterine cancer?) and. Location: UNITED STATES , 42 years of age, weighting 136.7 lb, Patient experienced the following unwanted or unexpected effects: asthenia, coma, cough, disease progression, dyspnoea, encephalopathy, febrile bone marrow aplasia, hallucination. During the same period patient was treated with UROMITEXAN (View Uromitexan Review and Uromitexan Label ), ZOPHREN (View Zophren Review and Zophren Label ), METHYLPREDNISOLONE (View Methylprednisolone Review and Methylprednisolone Label ), BENZODIAZEPINE (View Benzodiazepine Review and Benzodiazepine Label ), LEXOMIL (View Lexomil Review and Lexomil Label ), OXYGEN (View Oxygen Review and Oxygen Label ), SKENAN (View Skenan Review and Skenan Label ), IRON (View Iron Review and Iron Label ). Patient was hospitalized.

5582695-2 | Confusional State, Disorientation, Encephalopathy
on Dec 26, 2007 Male patient from UNITED STATES , 71 years of age, was diagnosed with sarcoma and was treated with Holoxan (View Usage). Patient had the following side effects: confusional state, disorientation, encephalopathy. Holoxan dosage: 3 Perfusions Of 8hrs Ovr 24hrs.. During the same period patient was treated with DOXORUBICIN HCL (View Doxorubicin Hcl Review and Doxorubicin Hcl Label ). Patient was hospitalized.

5582694-0 | Coma, Encephalopathy, Renal Failure
on Dec 26, 2007 Male patient from UNITED STATES , 64 years of age, was treated with Holoxan (View Usage). After Holoxan was administered, patient had the following side effects: coma, encephalopathy, renal failure. Holoxan dosage: . Patient was hospitalized.

5579385-9 | Arterial Occlusive Disease
Patient was taking Holoxan (View Usage). Patient experienced the following unwanted or unexpected effects: arterial occlusive disease on Dec 21, 2007 from UNITED STATES Additional patient health information: Male patient , 71 years of age, was diagnosed with leiomyosarcoma and. Holoxan dosage: . During the same period patient was treated with PARACETAMOL (View Paracetamol Review and Paracetamol Label ), ASCAL CARDIO (View Ascal Cardio Review and Ascal Cardio Label ), LOSEC I.V. (View Losec I.v. Review and Losec I.v. Label ), LYRICA (View Lyrica Review and Lyrica Label ), TRYPTIZOL (View Tryptizol Review and Tryptizol Label ), ALGELDRATE (View Algeldrate Review and Algeldrate Label ), OXYCONTIN (View Oxycontin Review and Oxycontin Label ), SIMVASTATIN (View Simvastatin Review and Simvastatin Label ). Patient was hospitalized.

5568200-5 | Encephalopathy, Metabolic Encephalopathy
Adverse event was reported on Dec 13, 2007 by a Female patient taking Holoxan (View Usage) (Dosage: ) was diagnosed with b-cell lymphoma recurrent and. Location: UNITED STATES , 54 years of age, Patient had the following side effects: encephalopathy, metabolic encephalopathy. During the same period patient was treated with CARBOPLATIN (View Carboplatin Review and Carboplatin Label ), ETOPOSIDE (View Etoposide Review and Etoposide Label ), UROMITEXAN (View Uromitexan Review and Uromitexan Label ). Patient was hospitalized.

5563240-4 | Bronchitis Pneumococcal, Lung Infection Pseudomonal
on Sep 20, 2007 Female patient from UNITED STATES , 57 years of age, was diagnosed with lymphoma (What is lymphoma?) and was treated with Holoxan (View Usage). After Holoxan was administered, patient had the following side effects: bronchitis pneumococcal, lung infection pseudomonal. Holoxan dosage: . During the same period patient was treated with CARBOPLATIN (View Carboplatin Review and Carboplatin Label ), ETOPOSIDE (View Etoposide Review and Etoposide Label ), MESNA (View Mesna Review and Mesna Label ), CARMUSTINE (View Carmustine Review and Carmustine Label ), RITUXIMAB (Taken From 16-nov-04 To 29-dec-04 Restarted On 22-mar-05 To 09-jan-06) (View Rituximab Review and Rituximab Label ), NEUPOGEN (1dosage Form = 300ug) (View Neupogen Review and Neupogen Label ), CYTARABINE (View Cytarabine Review and Cytarabine Label ), MELPHALAN (View Melphalan Review and Melphalan Label ). Patient was hospitalized.

5562648-0 | Encephalopathy, Metabolic Encephalopathy
on Dec 07, 2007 Female patient from UNITED STATES , 54 years of age, was diagnosed with b-cell lymphoma recurrent and was treated with Holoxan (View Usage). Patient experienced the following unwanted or unexpected effects: encephalopathy, metabolic encephalopathy. Holoxan dosage: . During the same period patient was treated with CARBOPLATIN (View Carboplatin Review and Carboplatin Label ), ETOPOSIDE (View Etoposide Review and Etoposide Label ), UROMITEXAN (View Uromitexan Review and Uromitexan Label ). Patient was hospitalized.

5503879-5 | Pulmonary Embolism
Patient was taking Holoxan (View Usage). Patient had the following side effects: pulmonary embolism (What is pulmonary embolism?) on Oct 24, 2007 from UNITED STATES Additional patient health information: Female patient , 41 years of age, . Holoxan dosage: .

5503772-8 | Sepsis
Adverse event was reported on Oct 18, 2007 by a Male patient taking Holoxan (View Usage) (Dosage: ) was diagnosed with diffuse large b-cell lymphoma and. Location: UNITED STATES , 42 years of age, After Holoxan was administered, patient had the following side effects: sepsis (What is sepsis?). During the same period patient was treated with ETOPOSIDE (View Etoposide Review and Etoposide Label ), CARBOPLATIN (View Carboplatin Review and Carboplatin Label ), RITUXIMAB (View Rituximab Review and Rituximab Label ). Patient was hospitalized.

5490647-6 | Oxygen Saturation Decreased, Petit Mal Epilepsy, Salivary Hypersecretion
on Sep 21, 2007 Female patient from UNITED STATES , child 6 years of age, was diagnosed with bone sarcoma and was treated with Holoxan (View Usage). Patient experienced the following unwanted or unexpected effects: oxygen saturation decreased, petit mal epilepsy, salivary hypersecretion. Holoxan dosage: . During the same period patient was treated with ETOPOPHOS (View Etopophos Review and Etopophos Label ), ZOFRAN (View Zofran Review and Zofran Label ), UROMITEXAN (View Uromitexan Review and Uromitexan Label ). Patient was hospitalized.

5490537-9 | Convulsion, Cystitis Haemorrhagic, Encephalopathy, Hyperhidrosis, Hypotension, Hypotonia, Malaise
on Oct 09, 2007 Male patient from UNITED STATES , child 3 years of age, weighting 33.07 lb, was diagnosed with rhabdomyosarcoma and was treated with Holoxan (View Usage). Patient had the following side effects: convulsion, cystitis haemorrhagic, encephalopathy, hyperhidrosis, hypotension, hypotonia, malaise. Holoxan dosage: . During the same period patient was treated with ONCOVIN (View Oncovin Review and Oncovin Label ), KETAMINE HCL (View Ketamine Hcl Review and Ketamine Hcl Label ), UROMITEXAN (View Uromitexan Review and Uromitexan Label ), ACTINOMYCIN D (View Actinomycin-d Review and Actinomycin-d Label ), ZOFRAN (View Zofran Review and Zofran Label ), VOGALENE (View Vogalene Review and Vogalene Label ). Patient was hospitalized.

5489841-X | Convulsion, Cystitis Haemorrhagic, Encephalopathy, Hyperhidrosis, Hypotension, Hypotonia, Malaise
Patient was taking Holoxan (View Usage). After Holoxan was administered, patient had the following side effects: convulsion, cystitis haemorrhagic, encephalopathy, hyperhidrosis, hypotension, hypotonia, malaise on Oct 09, 2007 from UNITED STATES Additional patient health information: Male patient , child 3 years of age, weighting 33.07 lb, was diagnosed with rhabdomyosarcoma and. Holoxan dosage: . During the same period patient was treated with ONCOVIN (View Oncovin Review and Oncovin Label ), KETAMINE HCL (View Ketamine Hcl Review and Ketamine Hcl Label ), UROMITEXAN (View Uromitexan Review and Uromitexan Label ), ACTINOMYCIN D (View Actinomycin-d Review and Actinomycin-d Label ), ZOFRAN (View Zofran Review and Zofran Label ), VOGALENE (View Vogalene Review and Vogalene Label ). Patient was hospitalized.

5431629-X | Convulsion, Cystitis Haemorrhagic, Hyperhidrosis, Hypotension, Hypotonia, Malaise
Adverse event was reported on Aug 20, 2007 by a Male patient taking Holoxan (View Usage) (Dosage: ) was diagnosed with rhabdomyosarcoma and. Location: UNITED STATES , child 3 years of age, Patient experienced the following unwanted or unexpected effects: convulsion, cystitis haemorrhagic, hyperhidrosis, hypotension, hypotonia, malaise. During the same period patient was treated with ONCOVIN (View Oncovin Review and Oncovin Label ), UROMITEXAN (View Uromitexan Review and Uromitexan Label ), ACTINOMYCIN D (View Actinomycin-d Review and Actinomycin-d Label ). Patient was hospitalized.

5429570-1 | Convulsion, Cystitis Haemorrhagic, Hyperhidrosis, Hypotension, Hypotonia, Malaise
on Aug 20, 2007 Male patient from UNITED STATES , child 3 years of age, was diagnosed with rhabdomyosarcoma and was treated with Holoxan (View Usage). Patient had the following side effects: convulsion, cystitis haemorrhagic, hyperhidrosis, hypotension, hypotonia, malaise. Holoxan dosage: . During the same period patient was treated with ONCOVIN (View Oncovin Review and Oncovin Label ), UROMITEXAN (View Uromitexan Review and Uromitexan Label ), ACTINOMYCIN D (View Actinomycin-d Review and Actinomycin-d Label ). Patient was hospitalized.

5418326-1 | Asthenia, Oedema, Oedema Peripheral, Pain In Extremity, Paraesthesia, Purpura, Rash Erythematous, Tachycardia
on Aug 08, 2007 Female patient from UNITED STATES , 17 years of age, was diagnosed with hodgkin's disease (What is hodgkin's disease?) and was treated with Holoxan (View Usage). After Holoxan was administered, patient had the following side effects: asthenia, oedema, oedema peripheral, pain in extremity, paraesthesia, purpura, rash erythematous, tachycardia. Holoxan dosage: . During the same period patient was treated with ETOPOSIDE (View Etoposide Review and Etoposide Label ), NAVELBINE (View Navelbine Review and Navelbine Label ), MITOGUAZONE (View Mitoguazone Review and Mitoguazone Label ), AMIKLIN (View Amiklin Review and Amiklin Label ), CEFTAZIDIME (View Ceftazidime Review and Ceftazidime Label ), BACTRIM (View Bactrim Review and Bactrim Label ), VANCOMYCIN (View Vancomycin Review and Vancomycin Label ), SYMBICORT (View Symbicort Review and Symbicort Label ). Patient was hospitalized.

5403295-0 | Encephalopathy, Hyperaesthesia, Malignant Neoplasm Progression, Myoclonus
Patient was taking Holoxan (View Usage). Patient experienced the following unwanted or unexpected effects: encephalopathy, hyperaesthesia, malignant neoplasm progression, myoclonus on Jul 25, 2007 from FRANCE Additional patient health information: Female patient , 57 years of age, was diagnosed with leiomyosarcoma and. Holoxan dosage: . During the same period patient was treated with ADRIAMYCIN PFS (View Adriamycin Pfs Review and Adriamycin Pfs Label ), DETICENE (View Deticene Review and Deticene Label ), UROMITEXAN (View Uromitexan Review and Uromitexan Label ), ZOFRAN (View Zofran Review and Zofran Label ), SOLU MEDROL (View Solu-medrol Review and Solu-medrol Label ), LEVOTHYROXINE SODIUM (View Levothyroxine Sodium Review and Levothyroxine Sodium Label ), ATENOLOL (View Atenolol Review and Atenolol Label ), TAREG (View Tareg Review and Tareg Label ). Patient was hospitalized.

5393751-6 | Encephalopathy, Hyponatraemia
Adverse event was reported on Jul 11, 2007 by a Female patient taking Holoxan (View Usage) (Dosage: ) was diagnosed with ewing's sarcoma and. Location: FRANCE , 70 years of age, Patient had the following side effects: encephalopathy, hyponatraemia. During the same period patient was treated with VINCRISTINE (View Vincristine Review and Vincristine Label ), ADRIAMYCIN PFS (View Adriamycin Pfs Review and Adriamycin Pfs Label ), ZOFRAN (View Zofran Review and Zofran Label ), SOLU MEDROL (View Solu-medrol Review and Solu-medrol Label ), CARDIOXANE (View Cardioxane Review and Cardioxane Label ), LEVOTHYROXINE SODIUM (View Levothyroxine Sodium Review and Levothyroxine Sodium Label ), PREGABALIN (View Pregabalin Review and Pregabalin Label ), ACTISKENAN (View Actiskenan Review and Actiskenan Label ). Patient was hospitalized.

5393681-X | Chills, Mucosal Inflammation, Palpitations, Pyrexia, Tooth Disorder, Weight Decreased
on Jul 13, 2007 Female patient from UNITED STATES , 36 years of age, was diagnosed with liposarcoma and was treated with Holoxan (View Usage). After Holoxan was administered, patient had the following side effects: chills, mucosal inflammation, palpitations, pyrexia, tooth disorder (What is tooth disorder?), weight decreased. Holoxan dosage: . During the same period patient was treated with ADRIBLASTINE (View Adriblastine Review and Adriblastine Label ), NEULASTA (View Neulasta Review and Neulasta Label ), EMEND (View Emend Review and Emend Label ), SOLU MEDROL (View Solu-medrol Review and Solu-medrol Label ), ZOFRAN (View Zofran Review and Zofran Label ), PRIMPERAN INJ (View Primperan Inj Review and Primperan Inj Label ), XANAX (View Xanax Review and Xanax Label ), CONTRACEPTIVE (View Contraceptive Review and Contraceptive Label ).

5392058-0 | Encephalopathy, Hyponatraemia
on Jul 11, 2007 Female patient from FRANCE , 70 years of age, was diagnosed with ewing's sarcoma and was treated with Holoxan (View Usage). Patient experienced the following unwanted or unexpected effects: encephalopathy, hyponatraemia. Holoxan dosage: . During the same period patient was treated with VINCRISTINE (View Vincristine Review and Vincristine Label ), ADRIAMYCIN PFS (View Adriamycin Pfs Review and Adriamycin Pfs Label ), ZOFRAN (View Zofran Review and Zofran Label ), SOLU MEDROL (View Solu-medrol Review and Solu-medrol Label ), CARDIOXANE (View Cardioxane Review and Cardioxane Label ), LEVOTHYROXINE SODIUM (View Levothyroxine Sodium Review and Levothyroxine Sodium Label ), PREGABALIN (View Pregabalin Review and Pregabalin Label ), ACTISKENAN (View Actiskenan Review and Actiskenan Label ). Patient was hospitalized.

5391509-5 | Encephalopathy
Patient was taking Holoxan (View Usage). Patient had the following side effects: encephalopathy on Jul 11, 2007 from FRANCE Additional patient health information: Female patient , 57 years of age, was diagnosed with leiomyosarcoma and. Holoxan dosage: . During the same period patient was treated with ADRIAMYCIN PFS (View Adriamycin Pfs Review and Adriamycin Pfs Label ), DETICENE (View Deticene Review and Deticene Label ), UROMITEXAN (View Uromitexan Review and Uromitexan Label ), ZOFRAN (View Zofran Review and Zofran Label ), SOLU MEDROL (View Solu-medrol Review and Solu-medrol Label ), LEVOTHYROXINE SODIUM (View Levothyroxine Sodium Review and Levothyroxine Sodium Label ), ATENOLOL (View Atenolol Review and Atenolol Label ), TAREG (View Tareg Review and Tareg Label ). Patient was hospitalized.

5340263-1 | Confusional State, Encephalopathy, Hallucination, Paranoia
Adverse event was reported on May 24, 2007 by a Male patient taking Holoxan (View Usage) (Dosage: ) was diagnosed with b-cell lymphoma and. Location: UNITED STATES , 49 years of age, After Holoxan was administered, patient had the following side effects: confusional state, encephalopathy, hallucination, paranoia. During the same period patient was treated with MABTHERA (View Mabthera Review and Mabthera Label ), ENDOXAN (View Endoxan Review and Endoxan Label ), DOXORUBICIN HCL (View Doxorubicin Hcl Review and Doxorubicin Hcl Label ), VINCRISTINE (View Vincristine Review and Vincristine Label ), CARBOPLATIN (View Carboplatin Review and Carboplatin Label ), ETOPOSIDE (View Etoposide Review and Etoposide Label ). Patient was hospitalized.

5316945-4 | Confusional State, Encephalopathy, Hallucination, Paranoia
on Apr 26, 2007 Male patient from UNITED STATES , 49 years of age, was diagnosed with b-cell lymphoma and was treated with Holoxan (View Usage). Patient experienced the following unwanted or unexpected effects: confusional state, encephalopathy, hallucination, paranoia. Holoxan dosage: . During the same period patient was treated with MABTHERA (View Mabthera Review and Mabthera Label ), ENDOXAN (View Endoxan Review and Endoxan Label ), DOXORUBICIN HCL (View Doxorubicin Hcl Review and Doxorubicin Hcl Label ), VINCRISTINE (View Vincristine Review and Vincristine Label ), CARBOPLATIN (View Carboplatin Review and Carboplatin Label ), ETOPOSIDE (View Etoposide Review and Etoposide Label ). Patient was hospitalized.

5267600-0 | Confusional State, Encephalopathy, Hallucination, Paranoia
on Mar 08, 2007 Male patient from UNITED STATES , 49 years of age, was diagnosed with b-cell lymphoma and was treated with Holoxan (View Usage). Patient had the following side effects: confusional state, encephalopathy, hallucination, paranoia. Holoxan dosage: . During the same period patient was treated with MABTHERA (View Mabthera Review and Mabthera Label ), ENDOXAN (View Endoxan Review and Endoxan Label ), DOXORUBICIN HCL (View Doxorubicin Hcl Review and Doxorubicin Hcl Label ), VINCRISTINE (View Vincristine Review and Vincristine Label ), CARBOPLATIN (View Carboplatin Review and Carboplatin Label ), ETOPOSIDE (View Etoposide Review and Etoposide Label ). Patient was hospitalized.

5254509-1 | Confusional State, Disorientation, Paranoia
Patient was taking Holoxan (View Usage). After Holoxan was administered, patient had the following side effects: confusional state, disorientation, paranoia on Feb 21, 2007 from UNITED STATES Additional patient health information: Male patient , 55 years of age, was diagnosed with b-cell lymphoma and. Holoxan dosage: . During the same period patient was treated with UROMITEXAN (View Uromitexan Review and Uromitexan Label ), ETOPOSIDE (View Etoposide Review and Etoposide Label ), CARBOPLATIN (View Carboplatin Review and Carboplatin Label ), MABTHERA (View Mabthera Review and Mabthera Label ). Patient was hospitalized.

5242743-6 | Anuria, Febrile Bone Marrow Aplasia, Multi-organ Failure, Neutropenia, Pancytopenia, Respiratory Failure, Salmonella Sepsis
Adverse event was reported on Feb 07, 2007 by a Male patient taking Holoxan (View Usage) (Dosage: ) was diagnosed with germ cell cancer and. Location: UNITED STATES , 37 years of age, Patient experienced the following unwanted or unexpected effects: anuria, febrile bone marrow aplasia, multi-organ failure, neutropenia, pancytopenia, respiratory failure, salmonella sepsis. During the same period patient was treated with CISPLATIN (View Cisplatin Review and Cisplatin Label ), GEMCITABINE (View Gemcitabine Review and Gemcitabine Label ). Patient was hospitalized.

5219524-2 | Febrile Bone Marrow Aplasia, Sepsis
on Jan 18, 2007 Male patient from UNITED STATES , 37 years of age, was diagnosed with germ cell cancer and was treated with Holoxan (View Usage). Patient had the following side effects: febrile bone marrow aplasia, sepsis (What is sepsis?). Holoxan dosage: . During the same period patient was treated with CISPLATIN (View Cisplatin Review and Cisplatin Label ), GEMCITABINE (View Gemcitabine Review and Gemcitabine Label ). Patient was hospitalized.

5214231-4 | Mania
on Jan 11, 2007 Male patient from UNITED STATES , 15 years of age, was diagnosed with cns germinoma and was treated with Holoxan (View Usage). After Holoxan was administered, patient had the following side effects: mania. Holoxan dosage: . During the same period patient was treated with VEPESID (View Vepesid Review and Vepesid Label ), SOLUDECADRON (View Soludecadron Review and Soludecadron Label ). Patient was hospitalized.

5208865-0 | Mania
Patient was taking Holoxan (View Usage). Patient experienced the following unwanted or unexpected effects: mania on Jan 08, 2007 from UNITED STATES Additional patient health information: Male patient , 15 years of age, was diagnosed with cns germinoma and. Holoxan dosage: . During the same period patient was treated with ETOPOSIDE (View Etoposide Review and Etoposide Label ), DEXAMETHASONE (View Dexamethasone Review and Dexamethasone Label ). Patient was hospitalized.

5154856-8 | Epistaxis, Pancytopenia
Adverse event was reported on Nov 09, 2006 by a Male patient taking Holoxan (View Usage) (Dosage: ) was diagnosed with germ cell cancer and. Location: UNITED STATES , 37 years of age, Patient had the following side effects: epistaxis, pancytopenia. During the same period patient was treated with GEMZAR (View Gemzar Review and Gemzar Label ), CISPLATIN (View Cisplatin Review and Cisplatin Label ). Patient was hospitalized.

5144030-3 | Confusional State, Disorientation, Paranoia
on Oct 25, 2006 Male patient from UNITED STATES , 55 years of age, was diagnosed with b-cell lymphoma and was treated with Holoxan (View Usage). After Holoxan was administered, patient had the following side effects: confusional state, disorientation, paranoia. Holoxan dosage: . During the same period patient was treated with UROMITEXAN (View Uromitexan Review and Uromitexan Label ), CARBOPLATIN (View Carboplatin Review and Carboplatin Label ), ETOPOSIDE (View Etoposide Review and Etoposide Label ), MABTHERA (View Mabthera Review and Mabthera Label ). Patient was hospitalized.

5142117-2 | Panniculitis, Purpura
on Oct 24, 2006 Female patient from UNITED STATES , 30 years of age, was diagnosed with hodgkin's disease (What is hodgkin's disease?) and was treated with Holoxan (View Usage). Patient experienced the following unwanted or unexpected effects: panniculitis, purpura. Holoxan dosage: . During the same period patient was treated with NAVELBINE (View Navelbine Review and Navelbine Label ), MITOGUAZONE (View Mitoguazone Review and Mitoguazone Label ), VEPESIDE SANDOZ (View Vepeside-sandoz Review and Vepeside-sandoz Label ). Patient was hospitalized.

5136490-9 | Abnormal Behaviour, Angiopathy, Aphasia, Cerebral Thrombosis, Confusional State, Encephalopathy, Hemiparesis, Impaired Self-care
Patient was taking Holoxan (View Usage). Patient had the following side effects: abnormal behaviour, angiopathy, aphasia (What is aphasia?), cerebral thrombosis, confusional state, encephalopathy, hemiparesis, impaired self-care on Sep 06, 2006 from UNITED STATES Additional patient health information: Male patient , 74 years of age, weighting 147.7 lb, was diagnosed with non-hodgkin's lymphoma and. Holoxan dosage: . During the same period patient was treated with UROMITEXAN (View Uromitexan Review and Uromitexan Label ), VEPESID (View Vepesid Review and Vepesid Label ). Patient was hospitalized and became disabled.