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Bruising (2)
Bruising,tiredness (2)
Tiredness (2)
Black Teeth (1)
Fevers (1)
I Feel Calmer. Does This Drug Sedate (1)
My Dosage Has Been Increased (1)
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Common Hydroxycarbamide Side Effects

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Hydroxycarbamide adverse events reported to FDA.

Have You Experienced unusual Hydroxycarbamide symptoms? PatientsVille.com collects and analyzes Hydroxycarbamide side effect and adverse reports submitted by Hydroxycarbamide users, such as .

Summary

FDA Adverse Reports: 33. View All

Hydroxycarbamide FDA safety alerts: No

Reported deaths: 4

Reported hospitalizations: 5

More About Hydroxycarbamide

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Most Reported
1Bruising,tiredness
2Bruising
3Tiredness
4Rash
5My Dosage Has Been Increased And I Feel Calmer. Does This Drug Sedate
6My Dosage Has Been Increased
7I Feel Calmer. Does This Drug Sedate
8Black Teeth
9Fevers
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Often additional risks of using a medication, such as Hydroxycarbamide, become known after product is used by a larger number of patients, for a longer period of time, and by patients with different health characteristics from those studied before drug approval. This page allows You to Find answers and discuss health symptoms with other Hydroxycarbamide users, Learn more about unwanted side effects & find ways to reduce them. Browse Hydroxycarbamide Adverse Reports reported to FDA and participate in Hydroxycarbamide discussion, find alternative treatments and find ways to avoid or reduce risks associated with using Hydroxycarbamide. You can also Post a question to users community or Ask a Doctor. PatientsVille.com is Your Complete Guide to all common, undocumented and undisclosed side effects associated with drugs and vaccines. Browse More Drug Reports Here: A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

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Hydroxycarbamide Adverse Effect Reports (FDA)

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6769461-7 | Urethral Cancer
on Jun 10, 2010 Female patient from UNITED KINGDOM , 87 years of age, was diagnosed with myeloproliferative disorder and was treated with Hydroxycarbamide (View Usage). Patient experienced the following unwanted or unexpected effects: urethral cancer. Hydroxycarbamide dosage: .

6684476-5 | Periodontal Disease, Tooth Loss
Patient was taking Hydroxycarbamide (View Usage). Patient had the following side effects: periodontal disease, tooth loss on Apr 09, 2010 from NETHERLANDS Additional patient health information: Male patient , 87 years of age, was diagnosed with thrombocytosis and. Hydroxycarbamide dosage: .

6655282-2 | Urethral Cancer
Adverse event was reported on Mar 25, 2010 by a Female patient taking Hydroxycarbamide (View Usage) (Dosage: ) was diagnosed with myeloproliferative disorder and. Location: UNITED KINGDOM , 87 years of age, After Hydroxycarbamide was administered, patient had the following side effects: urethral cancer.

6555610-2 | Anaemia, Duodenal Ulcer Perforation, Impaired Healing, Macrocytosis, Neutropenia, Neutrophil Hypersegmented Morphology Present, Sepsis
on Jan 25, 2010 Female patient from UNITED KINGDOM , 79 years of age, weighting 110.2 lb, was diagnosed with essential thrombocythaemia, gout (What is gout?), prophylaxis, hypertension, depression (What is depression?), blood cholesterol increased, thrombosis and was treated with Hydroxycarbamide (View Usage). Patient experienced the following unwanted or unexpected effects: anaemia, duodenal ulcer perforation, impaired healing, macrocytosis, neutropenia, neutrophil hypersegmented morphology present, sepsis (What is sepsis?). Hydroxycarbamide dosage: 09oct08-mar09:1g,sep08-23sep:500 Mg,24sep08-08oct08 Increased To 500/1000 Mg Alternative Days-1g. During the same period patient was treated with ALLOPURINOL (View Allopurinol Review and Allopurinol Label ), AMLODIPINE (View Amlodipine Review and Amlodipine Label ), CITALOPRAM (View Citalopram Review and Citalopram Label ), ATENOLOL (View Atenolol Review and Atenolol Label ), ETORICOXIB (View Etoricoxib Review and Etoricoxib Label ), SIMVASTATIN (View Simvastatin Review and Simvastatin Label ), WARFARIN SODIUM (View Warfarin Sodium Review and Warfarin Sodium Label ). Patient was hospitalized.


6478771-2 | Acute Febrile Neutrophilic Dermatosis
on Dec 02, 2009 Female patient from CHINA , 49 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Hydroxycarbamide (View Usage). Patient had the following side effects: acute febrile neutrophilic dermatosis. Hydroxycarbamide dosage: . During the same period patient was treated with TRETINOIN (View Tretinoin Review and Tretinoin Label ), CYTARABINE (View Cytarabine Review and Cytarabine Label ).

6461941-7 | Acute Febrile Neutrophilic Dermatosis
Patient was taking Hydroxycarbamide (View Usage). After Hydroxycarbamide was administered, patient had the following side effects: acute febrile neutrophilic dermatosis on Nov 23, 2009 from CHINA Additional patient health information: Female patient , 49 years of age, was diagnosed with acute promyelocytic leukaemia and. Hydroxycarbamide dosage: . During the same period patient was treated with TRETINOIN (View Tretinoin Review and Tretinoin Label ), CYTARABINE (View Cytarabine Review and Cytarabine Label ).

6397364-9 | Systemic Lupus Erythematosus
Adverse event was reported on Oct 05, 2009 by a Female patient taking Hydroxycarbamide (View Usage) (Dosage: ) was diagnosed with thrombocytopenia and. Location: TUNISIA , 73 years of age, Patient experienced the following unwanted or unexpected effects: systemic lupus erythematosus.

6273180-3 | Anaemia, Duodenal Ulcer Perforation, Impaired Healing, Neutropenia, Sepsis
on Jul 15, 2009 Female patient from UNITED KINGDOM , 79 years of age, weighting 110.2 lb, was diagnosed with essential thrombocythaemia, gout (What is gout?), hypertension, depression (What is depression?) and was treated with Hydroxycarbamide (View Usage). Patient had the following side effects: anaemia, duodenal ulcer perforation, impaired healing, neutropenia, sepsis (What is sepsis?). Hydroxycarbamide dosage: On Sep08-nov08:1 G On Nov08-mar09:500mg. During the same period patient was treated with ALLOPURINOL (View Allopurinol Review and Allopurinol Label ), AMLODIPINE (View Amlodipine Review and Amlodipine Label ), CITALOPRAM HYDROBROMIDE (View Citalopram Hydrobromide Review and Citalopram Hydrobromide Label ). Patient was hospitalized.

6250405-1 | Infected Skin Ulcer
on Jun 26, 2009 Male patient from ITALY , 50 years of age, was treated with Hydroxycarbamide (View Usage). After Hydroxycarbamide was administered, patient had the following side effects: infected skin ulcer. Hydroxycarbamide dosage: .

6245375-6 | Infected Skin Ulcer
Patient was taking Hydroxycarbamide (View Usage). Patient experienced the following unwanted or unexpected effects: infected skin ulcer on Jun 22, 2009 from ITALY Additional patient health information: Male patient , 50 years of age, . Hydroxycarbamide dosage: .

6201045-1 | Anaemia, Neutropenia, Pulmonary Oedema
Adverse event was reported on May 15, 2009 by a Female patient taking Hydroxycarbamide (View Usage) (Dosage: 1 Dosage Form = 642 Mg Mean Dose) was diagnosed with thrombocythaemia and. Location: GREECE , 81 years of age, Patient had the following side effects: anaemia, neutropenia, pulmonary oedema. During the same period patient was treated with ANAGRELIDE HCL (1df=mean Daily Dose 0.64mg) (View Anagrelide Hcl Review and Anagrelide Hcl Label ).

6201044-X | Erythromelalgia, Therapeutic Response Decreased
on May 15, 2009 Female patient from GREECE , 53 years of age, was diagnosed with thrombocythaemia and was treated with Hydroxycarbamide (View Usage). After Hydroxycarbamide was administered, patient had the following side effects: erythromelalgia, therapeutic response decreased. Hydroxycarbamide dosage: . During the same period patient was treated with ANAGRELIDE HCL (1df=mean Daily Dose 250 Mg) (View Anagrelide Hcl Review and Anagrelide Hcl Label ).

6201043-8 | Angina Pectoris, Gene Mutation Identification Test Positive
on May 15, 2009 Male patient from GREECE , 76 years of age, was diagnosed with polycythaemia vera and was treated with Hydroxycarbamide (View Usage). Patient experienced the following unwanted or unexpected effects: angina pectoris, gene mutation identification test positive. Hydroxycarbamide dosage: 1 Dosage Form = 714 Mg. During the same period patient was treated with ANAGRELIDE HCL (1df=mean Daily Dose 0.64mg) (View Anagrelide Hcl Review and Anagrelide Hcl Label ).

6201042-6 | Anaemia, Haematuria
Patient was taking Hydroxycarbamide (View Usage). Patient had the following side effects: anaemia, haematuria on May 15, 2009 from GREECE Additional patient health information: Male patient , 79 years of age, was diagnosed with myelofibrosis and. Hydroxycarbamide dosage: 1 Dosage Form = 714 Mg. During the same period patient was treated with CLOPIDOGREL BISULFATE (1df=mean Daily Dose 1.5mg) (View Clopidogrel Bisulfate Review and Clopidogrel Bisulfate Label ), ANAGRELIDE HCL (1 Doseage Form = 0.7 Mg) (View Anagrelide Hcl Review and Anagrelide Hcl Label ).

6190435-1 | Anaemia, Haematuria
Adverse event was reported on May 11, 2009 by a Male patient taking Hydroxycarbamide (View Usage) (Dosage: ) was diagnosed with myelofibrosis and. Location: GREECE , 79 years of age, After Hydroxycarbamide was administered, patient had the following side effects: anaemia, haematuria. During the same period patient was treated with CLOPIDOGREL BISULFATE (1df=mean Daily Dose 1.5mg) (View Clopidogrel Bisulfate Review and Clopidogrel Bisulfate Label ), ANAGRELIDE HCL (View Anagrelide Hcl Review and Anagrelide Hcl Label ).

6190433-8 | Erythromelalgia, Therapeutic Response Decreased
on May 11, 2009 Female patient from GREECE , 53 years of age, was diagnosed with thrombocythaemia and was treated with Hydroxycarbamide (View Usage). Patient experienced the following unwanted or unexpected effects: erythromelalgia, therapeutic response decreased. Hydroxycarbamide dosage: . During the same period patient was treated with ANAGRELIDE HCL (1df=mean Daily Dose 250 Mg) (View Anagrelide Hcl Review and Anagrelide Hcl Label ).

6190429-6 | Anaemia, Gene Mutation, Neutropenia, Pulmonary Oedema
on May 11, 2009 Female patient from GREECE , 81 years of age, was diagnosed with thrombocythaemia and was treated with Hydroxycarbamide (View Usage). Patient had the following side effects: anaemia, gene mutation, neutropenia, pulmonary oedema. Hydroxycarbamide dosage: . During the same period patient was treated with ANAGRELIDE HCL (1df=mean Daily Dose .64mg) (View Anagrelide Hcl Review and Anagrelide Hcl Label ).

6190426-0 | Angina Pectoris
Patient was taking Hydroxycarbamide (View Usage). After Hydroxycarbamide was administered, patient had the following side effects: angina pectoris on May 11, 2009 from GREECE Additional patient health information: Male patient , 76 years of age, was diagnosed with polycythaemia vera and. Hydroxycarbamide dosage: . During the same period patient was treated with ANAGRELIDE HCL (1df=mean Daily Dose .64mg) (View Anagrelide Hcl Review and Anagrelide Hcl Label ).

5968003-3 | Cerebrovascular Accident, Intracranial Venous Sinus Thrombosis, Osteonecrosis
Adverse event was reported on Nov 24, 2008 by a Male patient taking Hydroxycarbamide (View Usage) (Dosage: ) was diagnosed with sickle cell anaemia with crisis and. Location: LEBANON , 21 years of age, Patient experienced the following unwanted or unexpected effects: cerebrovascular accident, intracranial venous sinus thrombosis, osteonecrosis (What is osteonecrosis?).

5957625-1 | Cerebrovascular Accident, Intracranial Venous Sinus Thrombosis, Osteonecrosis
on Nov 17, 2008 Male patient from LEBANON , 21 years of age, was diagnosed with sickle cell anaemia with crisis and was treated with Hydroxycarbamide (View Usage). Patient had the following side effects: cerebrovascular accident, intracranial venous sinus thrombosis, osteonecrosis (What is osteonecrosis?). Hydroxycarbamide dosage: .

5895534-7 | Actinic Keratosis, Keratoacanthoma, Nail Pigmentation, Skin Hyperpigmentation, Squamous Cell Carcinoma, Ulcer
on Sep 22, 2008 Male patient from ITALY , 81 years of age, was diagnosed with myeloproliferative disorder, anaemia, skin cancer (What is skin cancer?), hepatic failure, coagulopathy and was treated with Hydroxycarbamide (View Usage). After Hydroxycarbamide was administered, patient had the following side effects: actinic keratosis, keratoacanthoma, nail pigmentation, skin hyperpigmentation, squamous cell carcinoma, ulcer (What is ulcer?). Hydroxycarbamide dosage: . During the same period patient was treated with IMIQUIMOD 5% (5%,once Daily For 5 Days Per Week For 6 To 10 Weeks + 5% (10 Mg/cm Of Skin Cancer)) (View Imiquimod 5% Review and Imiquimod 5% Label ), IRON (View Iron Review and Iron Label ), FOLIC ACID (View Folic Acid Review and Folic Acid Label ).

5574592-3 | Photosensitivity Reaction
Patient was taking Hydroxycarbamide (View Usage). Patient experienced the following unwanted or unexpected effects: photosensitivity reaction on Dec 26, 2007 from SPAIN Additional patient health information: Female patient , 56 years of age, . Hydroxycarbamide dosage: . During the same period patient was treated with ISONIAZID (View Isoniazid Review and Isoniazid Label ), ETHAMBUTOL HYDROCHLORIDE (View Ethambutol Hydrochloride Review and Ethambutol Hydrochloride Label ), LOSARTAN POTASSIUM (View Losartan Potassium Review and Losartan Potassium Label ), SPIRONOLACTONE (View Spironolactone Review and Spironolactone Label ).

5571435-9 | Anaemia, Leukopenia, Malignant Neoplasm Progression, Thrombocytopenia
Adverse event was reported on Dec 17, 2007 by a Male patient taking Hydroxycarbamide (View Usage) (Dosage: Dose Reduced Decreased To 500 Mg Once Daily.) was diagnosed with glioblastoma multiforme and. Location: UNITED STATES , 58 years of age, Patient had the following side effects: anaemia, leukopenia, malignant neoplasm progression, thrombocytopenia. During the same period patient was treated with SULFAMETHOXAZOLE AND TRIMETHOPRIM (View Sulfamethoxazole And Trimethoprim Review and Sulfamethoxazole And Trimethoprim Label ), GLEEVEC (View Gleevec Review and Gleevec Label ), LEVETIRACETAM (View Levetiracetam Review and Levetiracetam Label ), PANTOPRAZOLE SODIUM (View Pantoprazole Sodium Review and Pantoprazole Sodium Label ), LEVOTHYROXINE SODIUM (View Levothyroxine Sodium Review and Levothyroxine Sodium Label ), DEXAMETHASONE TAB (View Dexamethasone Tab Review and Dexamethasone Tab Label ).

5566262-2 | Photosensitivity Reaction
on Dec 17, 2007 Female patient from SPAIN , 56 years of age, was treated with Hydroxycarbamide (View Usage). After Hydroxycarbamide was administered, patient had the following side effects: photosensitivity reaction. Hydroxycarbamide dosage: . During the same period patient was treated with ISONIAZID (View Isoniazid Review and Isoniazid Label ), ETHAMBUTOL HYDROCHLORIDE (View Ethambutol Hydrochloride Review and Ethambutol Hydrochloride Label ), LOSARTAN POTASSIUM (View Losartan Potassium Review and Losartan Potassium Label ), SPIRONOLACTONE (View Spironolactone Review and Spironolactone Label ).

5520145-2 | Leprosy
on Nov 12, 2007 Male patient from BRAZIL , 39 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Hydroxycarbamide (View Usage). Patient experienced the following unwanted or unexpected effects: leprosy. Hydroxycarbamide dosage: .

5515854-5 | Bone Marrow Failure, Chills, Diarrhoea, Hyperhidrosis
Patient was taking Hydroxycarbamide (View Usage). Patient had the following side effects: bone marrow failure, chills, diarrhoea, hyperhidrosis on Nov 09, 2007 from UNITED KINGDOM Additional patient health information: Male patient , 66 years of age, weighting 167.6 lb, was diagnosed with psoriasis, prophylaxis, stomach discomfort, pain (What is pain?), myalgia and. Hydroxycarbamide dosage: . During the same period patient was treated with ALENDRONIC ACID (View Alendronic Acid Review and Alendronic Acid Label ), LANSOPRAZOLE (View Lansoprazole Review and Lansoprazole Label ), PARACETAMOL (View Paracetamol Review and Paracetamol Label ), PREDNISOLONE (View Prednisolone Review and Prednisolone Label ). Patient was hospitalized.

5503781-9 | Back Pain, Neck Pain, Pyrexia, Rash Maculo-papular
Adverse event was reported on Jun 08, 2007 by a Female patient taking Hydroxycarbamide (View Usage) (Dosage: ) was diagnosed with polycythaemia vera, prophylaxis and. Location: UNITED KINGDOM , 52 years of age, weighting 154.3 lb, After Hydroxycarbamide was administered, patient had the following side effects: back pain (What is back pain?), neck pain, pyrexia, rash maculo-papular. During the same period patient was treated with ALLOPURINOL (View Allopurinol Review and Allopurinol Label ), ASPIRIN (View Aspirin Review and Aspirin Label ), SUMATRIPTAN SUCCINATE (View Sumatriptan Succinate Review and Sumatriptan Succinate Label ), LEVOTHYROXINE SODIUM (View Levothyroxine Sodium Review and Levothyroxine Sodium Label ).

5315485-6 | Tumour Lysis Syndrome
on May 01, 2007 Male patient from LEBANON , 61 years of age, was diagnosed with chronic myelomonocytic leukaemia and was treated with Hydroxycarbamide (View Usage). Patient experienced the following unwanted or unexpected effects: tumour lysis syndrome. Hydroxycarbamide dosage: . During the same period patient was treated with ALLOPURINOL (View Allopurinol Review and Allopurinol Label ). Patient was hospitalized.

5306056-6 | Bone Marrow Failure
on Apr 20, 2006 Male patient from UNITED STATES , 64 years of age, weighting 200.6 lb, was diagnosed with myelodysplastic syndrome and was treated with Hydroxycarbamide (View Usage). Patient had the following side effects: bone marrow failure. Hydroxycarbamide dosage: . During the same period patient was treated with ARANESP (View Aranesp Review and Aranesp Label ), ALLOPURINOL (View Allopurinol Review and Allopurinol Label ).

5135771-2 | Dysphagia
Patient was taking Hydroxycarbamide (View Usage). After Hydroxycarbamide was administered, patient had the following side effects: dysphagia on Oct 23, 2006 from FRANCE Additional patient health information: Female patient , 78 years of age, was diagnosed with thrombocythaemia and. Hydroxycarbamide dosage: .

4716501-2 | Myocardial Infarction
Adverse event was reported on Jul 11, 2005 by a Male patient taking Hydroxycarbamide (View Usage) (Dosage: ) was diagnosed with sickle cell anaemia and. Location: BRAZIL , 28 years of age, Patient experienced the following unwanted or unexpected effects: myocardial infarction. Patient was hospitalized.

4605052-1 | Pyoderma Gangrenosum
on Feb 28, 2005 Female patient from , 59 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Hydroxycarbamide (View Usage). Patient had the following side effects: pyoderma gangrenosum. Hydroxycarbamide dosage: . During the same period patient was treated with RIFAMPICIN (View Rifampicin Review and Rifampicin Label ), ALLOPURINOL (View Allopurinol Review and Allopurinol Label ), PASINAH (View Pasinah Review and Pasinah Label ).

4602635-X | Pyoderma Gangrenosum, Skin Ulcer
on Feb 25, 2005 Male patient from , 75 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Hydroxycarbamide (View Usage). After Hydroxycarbamide was administered, patient had the following side effects: pyoderma gangrenosum, skin ulcer. Hydroxycarbamide dosage: . During the same period patient was treated with LANSOPRAZOLE (View Lansoprazole Review and Lansoprazole Label ), ASPIRIN (View Aspirin Review and Aspirin Label ), ALLOPURINOL (View Allopurinol Review and Allopurinol Label ).


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Hydroxycarbamide Questions, Answers, Feedback and Comments

Comments to date: 1. Page 1 of 1.

cathy   liverpool 

4:18am on Wednesday, December 23rd, 2009

my name is Cathy and am on hydroxycarbamide and am getting a lot of bruising all over my legs and th... read more »

To find out about documented side effects or safety concerns read either the drug label or the drug's package insert. You may also want to speak with your pharmacist or healthcare provider. All medicines have benefits and risks. The risks are the chances that something unwanted or unexpected could happen to you when you use them. You can protect yourself by searching summaries of recent safety alerts, adverse reports. Sometimes there are risks that only come to light after a medical product gets on the market and is used in a larger number of patients, for a longer period of time, and in patients whose health characteristics are different from those of the patients studied before approval.

Be aware of the following potential Hydroxycarbamide risks to be aware of: 1. Watch for any Serious adverse events, such as life-threatening situation, which can require an admission to hospital or longer-than-expected hospital stay, permanent disability, birth defect, miscarriage, stillbirth, or birth with serious disease requires medical care to prevent permanent damage
2. Any potential Hydroxycarbamide quality problem: suspected counterfeit product, potentially contaminated product indicated by suspicious odor or unusual color, inaccurate or unreadable product labeling
3. Potential Hydroxycarbamide use error: mixing up products with similar drug names or packaging, taking wrong dose of a drug because of confusing dosing instructions on label
4. When applicable, Problems with different manufacturer of same medicine: not getting same results from a generic drug as a brand name drug, or from another generic

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Hydroxycarbamide Reactions
Actinic Keratosis
Acute Febrile Neutrophilic Dermatosis
Anaemia
Angina Pectoris
Back PainWhat is Back pain?
Bone Marrow Failure
Cerebrovascular Accident
Chills
Death
Diarrhoea
Duodenal Ulcer Perforation
Dysphagia
Erythromelalgia
Gene Mutation
Gene Mutation Identification Test Positive
Haematuria
Hyperhidrosis
Impaired Healing
Infected Skin Ulcer
Intracranial Venous Sinus Thrombosis
Keratoacanthoma
Leprosy
Neutropenia
OsteonecrosisWhat is Osteonecrosis?
Photosensitivity Reaction
Pulmonary Oedema
Pyoderma Gangrenosum
SepsisWhat is Sepsis?
Therapeutic Response Decreased
Urethral Cancer
Hydroxycarbamide Side Effects Notice - The material on this site is for informational purposes only, and is not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. PatientsVille.com does not provide medical advice, diagnosis or treatment. The information regarding Hydroxycarbamide adverse reports, reviews and polls contained on PatientsVille.com site has not been scientifically or otherwise verified as to a cause and effect relationship and cannot be used to estimate the incidence of adverse drug reactions or for establishing or changing of patient treatments. Thank you for visiting Patientsville.com!