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Imuran Side Effects

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Common Imuran Side Effects


The most commonly reported Imuran side effects (click to view or check a box to report):

Diarrhoea (33)
Fatigue (31)
Injection Site Pain (29)
Pyrexia (25)
Arthralgia (25)
Headache (24)
Pain (22)
Crohn's Disease (21)
Abdominal Pain (20)
Vomiting (19)
Cough (17)
Nausea (16)
Anaemia (16)
Pancreatitis (15)
Asthenia (14)
Pneumonia (13)
Dyspnoea (12)
Pain In Extremity (11)
Injection Site Haematoma (11)
Rash (10)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Imuran Side Effects Reported to FDA



Imuran Side Effect Report#9962836
Abdominal Distension, Weight Increased
This is a report of a female patient (weight: NA) from Country Not Specified, suffering from the following health symptoms/conditions: NA, who was treated with Imuran (dosage: NA, start time:
Feb 10, 2013), combined with:
  • Vitamin C
  • Tylenol
  • Norco
  • Humira
  • Flagyl
and developed a serious reaction and side effect(s): Abdominal Distension, Weight Increased after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Imuran treatment in female patients, resulting in Abdominal Distension side effect.
Imuran Side Effect Report#9552981
Colitis Ulcerative, Skin Lesion, Skin Infection, Staphylococcal Infection, Immunosuppression, Injection Site Haematoma, Pruritus, Insomnia
This report suggests a potential Imuran (azathioprine) Colitis Ulcerative side effect(s) that can have serious consequences. A 41-year-old male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: NA and used Imuran (azathioprine) (dosage: NA) starting NS. After starting Imuran (azathioprine) the patient began experiencing various side effects, including: Colitis Ulcerative, Skin Lesion, Skin Infection, Staphylococcal Infection, Immunosuppression, Injection Site Haematoma, Pruritus, InsomniaAdditional drugs used concurrently:
  • Humira
  • Lisinopril
  • Gabapentin
  • Tramadol
  • Bupropion
  • Celebrex
  • Ranitidine
  • Acetaminophen W/oxycodone
The patient was hospitalized. Although Imuran (azathioprine) demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Colitis Ulcerative, may still occur.
Imuran Side Effect Report#9552963
Croup Infectious
This Croup Infectious problem was reported by a health professional from US. A 5-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Imuran (azathioprine) (dosage: NA). The following drugs were being taken at the same time:
  • Remicade
  • Dextrin
  • Multivit
  • Lansoprazole
  • Probiotics
When using Imuran (azathioprine), the patient experienced the following unwanted symptoms/side effects: Croup InfectiousThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Croup Infectious, may become evident only after a product is in use by the general population.
Imuran Side Effect Report#9552931
Infected Skin Ulcer, Localised Infection, Hyperkeratosis, Skin Ulcer
This Infected Skin Ulcer side effect was reported by a consumer or non-health professional from US. A 81-year-old female patient (weight:NA) experienced the following symptoms/conditions: rheumatoid arthritis.The patient was prescribed Imuran (azathioprine) (drug dosage: NA), which was initiated on
Apr 01, 2012. Concurrently used drugs:
  • Humira
  • Celebrex
  • Metoprolol
  • Actonel
  • Plavix
  • Asa
  • Iron
  • Simvastatin
.After starting to take Imuran (azathioprine) the consumer reported adverse symptoms, such as: Infected Skin Ulcer, Localised Infection, Hyperkeratosis, Skin UlcerThese side effects may potentially be related to Imuran (azathioprine). The patient was hospitalized.
Imuran Side Effect Report#9538864
Pancreatitis, Abdominal Pain, Gastrointestinal Inflammation, Diarrhoea, Dehydration, Proctitis, Haematochezia, Clostridial Infection
This is a report of a 31-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: crohn^s disease, who was treated with Imuran (azathioprine) (dosage: NA, start time:
Nov 23, 2011), combined with:
  • Humira (40 Mg; Qow; Inj)
  • Asacol
  • Prednisone
and developed a serious reaction and side effect(s): Pancreatitis, Abdominal Pain, Gastrointestinal Inflammation, Diarrhoea, Dehydration, Proctitis, Haematochezia, Clostridial Infection after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Imuran (azathioprine) treatment in female patients, resulting in Pancreatitis side effect. The patient was hospitalized.
Imuran Side Effect Report#9538852
Rectal Abscess, Fistula, Crohn^s Disease, Malaise, Aphthous Stomatitis, Pyrexia, Diarrhoea, Headache, Fatigue
This report suggests a potential Imuran (azathioprine) Rectal Abscess side effect(s) that can have serious consequences. A 24-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: crohn^s disease and used Imuran (azathioprine) (dosage: NA) starting
Jun 21, 2012. After starting Imuran (azathioprine) the patient began experiencing various side effects, including: Rectal Abscess, Fistula, Crohn^s Disease, Malaise, Aphthous Stomatitis, Pyrexia, Diarrhoea, Headache, FatigueAdditional drugs used concurrently:
  • Humira
  • Protonix
  • Questran
  • Iron
  • Cyanocobalamin
The patient was hospitalized. Although Imuran (azathioprine) demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Rectal Abscess, may still occur.
Imuran Side Effect Report#9538838
Pain, Vomiting
This Pain problem was reported by a health professional from US. A 44-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On 201205 this consumer started treatment with Imuran (azathioprine) (dosage: Unk). The following drugs were being taken at the same time: NA. When using Imuran (azathioprine), the patient experienced the following unwanted symptoms/side effects: Pain, VomitingThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Pain, may become evident only after a product is in use by the general population.
Imuran Side Effect Report#9538826
Pancreatitis, Clostridial Infection, Diarrhoea, Dehydration, Weight Decreased, Abdominal Pain, Pain, Oral Herpes, Injection Site Haematoma
This Pancreatitis side effect was reported by a consumer or non-health professional from US. A 31-year-old female patient (weight:NA) experienced the following symptoms/conditions: crohn^s disease.The patient was prescribed Imuran (azathioprine) (drug dosage: NA), which was initiated on 201202. Concurrently used drugs:
  • Humira
  • Mesalazine
  • Flonase
  • Cetirizine
  • Ranitidine
  • Bifidobacterium Lactis
  • Norlestrin Fe
  • Paracetamol
.After starting to take Imuran (azathioprine) the consumer reported adverse symptoms, such as: Pancreatitis, Clostridial Infection, Diarrhoea, Dehydration, Weight Decreased, Abdominal Pain, Pain, Oral Herpes, Injection Site HaematomaThese side effects may potentially be related to Imuran (azathioprine). The patient was hospitalized.
Imuran Side Effect Report#9538810
Bone Marrow Failure, Pancytopenia
This is a report of a 27-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: autoimmune hepatitis, who was treated with Imuran (azathioprine) (dosage: NA, start time:
May 02, 2012), combined with:
  • Oral Contraceptive Nos
and developed a serious reaction and side effect(s): Bone Marrow Failure, Pancytopenia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Imuran (azathioprine) treatment in female patients, resulting in Bone Marrow Failure side effect. The patient was hospitalized.
Imuran Side Effect Report#9538777
Pneumonia
This report suggests a potential Imuran (azathioprine) Pneumonia side effect(s) that can have serious consequences. A 70-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: NA and used Imuran (azathioprine) (dosage: NA) starting
Sep 23, 2011. After starting Imuran (azathioprine) the patient began experiencing various side effects, including: PneumoniaAdditional drugs used concurrently:
  • Ambrisentan
  • Ambrisentan
  • Ambrisentan
The patient was hospitalized. Although Imuran (azathioprine) demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Pneumonia, may still occur.
Imuran Side Effect Report#9538766
Histoplasmosis Disseminated, Crohn^s Disease
This Histoplasmosis Disseminated problem was reported by a physician from US. A 45-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: crohn^s disease. On 200903 this consumer started treatment with Imuran (azathioprine) (dosage: NA). The following drugs were being taken at the same time:
  • Humira
When using Imuran (azathioprine), the patient experienced the following unwanted symptoms/side effects: Histoplasmosis Disseminated, Crohn^s DiseaseAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Histoplasmosis Disseminated, may become evident only after a product is in use by the general population.
Imuran Side Effect Report#9538763
Hypersensitivity, Blister, Swelling Face, Pyrexia
This Hypersensitivity side effect was reported by a consumer or non-health professional from US. A 22-year-old male patient (weight:NA) experienced the following symptoms/conditions: colitis ulcerative.The patient was prescribed Imuran (azathioprine) (drug dosage: Unk Po), which was initiated on
Feb 09, 2012. Concurrently used drugs:
  • Asacol
  • Asacol
.After starting to take Imuran (azathioprine) the consumer reported adverse symptoms, such as: Hypersensitivity, Blister, Swelling Face, PyrexiaThese side effects may potentially be related to Imuran (azathioprine). The patient was hospitalized.
Imuran Side Effect Report#9538750
Herpes Zoster
This is a report of a 25-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: NA, who was treated with Imuran (azathioprine) (dosage: NA, start time:
Feb 22, 2012), combined with:
  • Benlysta
  • Prednisone
and developed a serious reaction and side effect(s): Herpes Zoster after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Imuran (azathioprine) treatment in female patients, resulting in Herpes Zoster side effect.
Imuran Side Effect Report#9362986
Jc Virus Infection, Progressive Multifocal Leukoencephalopathy
This report suggests a potential Imuran (azathioprine) Jc Virus Infection side effect(s) that can have serious consequences. A 72-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: dermatomyositis and used Imuran (azathioprine) (dosage: NA) starting NS. After starting Imuran (azathioprine) the patient began experiencing various side effects, including: Jc Virus Infection, Progressive Multifocal LeukoencephalopathyAdditional drugs used concurrently: NA. Although Imuran (azathioprine) demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Jc Virus Infection, may still occur.
Imuran Side Effect Report#9173218
Lupus-like Syndrome, Antinuclear Antibody Positive, Pancreatitis, Nasopharyngitis, Bronchitis, Blood Triglycerides Increased, Hypothyroidism, Crohn^s Disease, Disease Recurrence
This Lupus-like Syndrome problem was reported by a consumer or non-health professional from US. A 59-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: crohn^s disease,short-bowel syndrome. On 201103 this consumer started treatment with Imuran (dosage: NA). The following drugs were being taken at the same time:
  • Creon
  • Humira
  • Triamterene And Hydrochlorothiazide
  • Levemir
  • Tylenol W/codeine
When using Imuran, the patient experienced the following unwanted symptoms/side effects: Lupus-like Syndrome, Antinuclear Antibody Positive, Pancreatitis, Nasopharyngitis, Bronchitis, Blood Triglycerides Increased, Hypothyroidism, Crohn^s Disease, Disease RecurrenceThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Lupus-like Syndrome, may become evident only after a product is in use by the general population.
Imuran Side Effect Report#9159756
Throat Tightness, Dyspnoea, Urticaria, Palpitations, Feeling Abnormal, Vomiting, Eating Disorder, Fatigue
This Throat Tightness side effect was reported by a consumer or non-health professional from US. A 28-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Imuran (azathioprine) (drug dosage: NA), which was initiated on
Nov 18, 2012. Concurrently used drugs:
  • Humira
.After starting to take Imuran (azathioprine) the consumer reported adverse symptoms, such as: Throat Tightness, Dyspnoea, Urticaria, Palpitations, Feeling Abnormal, Vomiting, Eating Disorder, FatigueThese side effects may potentially be related to Imuran (azathioprine). The patient was hospitalized.
Imuran Side Effect Report#9061809
Malnutrition, Renal Disorder, Condition Aggravated, Dehydration, Haemoglobin Decreased, Weight Decreased, Crohn^s Disease
This is a report of a 54-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: crohn^s disease, who was treated with Imuran (azathioprine) (dosage: NA, start time: 201101), combined with:
  • Humira
  • Zyloprim
and developed a serious reaction and side effect(s): Malnutrition, Renal Disorder, Condition Aggravated, Dehydration, Haemoglobin Decreased, Weight Decreased, Crohn^s Disease after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Imuran (azathioprine) treatment in female patients, resulting in Malnutrition side effect.
Imuran Side Effect Report#9061596
Pneumonia, Systemic Lupus Erythematosus, Gastric Haemorrhage, Crohn^s Disease, Influenza, Muscle Spasms, Muscle Spasms, Vomiting, Dehydration
This report suggests a potential Imuran (azathioprine) Pneumonia side effect(s) that can have serious consequences. A 36-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: NA and used Imuran (azathioprine) (dosage: NA) starting 201006. After starting Imuran (azathioprine) the patient began experiencing various side effects, including: Pneumonia, Systemic Lupus Erythematosus, Gastric Haemorrhage, Crohn^s Disease, Influenza, Muscle Spasms, Muscle Spasms, Vomiting, DehydrationAdditional drugs used concurrently:
  • Belimumab
  • Zofran
  • Plaquenil /00072602/
  • Normal Immunoglobulin
  • Morphine Sulfate
  • Diovan Hct
  • Hyoscyamine
  • Gabapentin
Although Imuran (azathioprine) demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Pneumonia, may still occur.
Imuran Side Effect Report#9034530
Alopecia, Diarrhoea, Alanine Aminotransferase Increased
This Alopecia problem was reported by a physician from US. A 43-year-old patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Aug 18, 2012 this consumer started treatment with Imuran (dosage: NA). The following drugs were being taken at the same time: NA. When using Imuran, the patient experienced the following unwanted symptoms/side effects: Alopecia, Diarrhoea, Alanine Aminotransferase IncreasedAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Alopecia, may become evident only after a product is in use by the general population.
Imuran Side Effect Report#8891452
Respiratory Failure, Hypoxia, Cardiac Arrest
This Respiratory Failure side effect was reported by a consumer or non-health professional from US. A 76-year-old male patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Imuran (drug dosage: 50 Mg/qd;po), which was initiated on
Jul 05, 2012. Concurrently used drugs:
  • Rapaflo (8 Mg;qd;po)
  • Losartan Potassium (100 Mg; Qd; Po)
  • Prednisone (10 Mg; Qd; Po)
  • Lovastatin (40 Mg; Bid; Po)
  • Metformin Hydrochloride (1000 Mg; Bid; Po)
  • Metoprolol (50 Mg; Bid; Po)
  • Salbutamol (2 Puffs; Prn; Inh)
  • Advair (500 Mcg; Qd; Inh)
.After starting to take Imuran the consumer reported adverse symptoms, such as: Respiratory Failure, Hypoxia, Cardiac ArrestThese side effects may potentially be related to Imuran.
Imuran Side Effect Report#8816337
Migraine, Nausea, Contusion, Gastrointestinal Pain, Pharyngeal Haemorrhage, Tremor, Chills, Heart Rate Increased, Hyperhidrosis
This is a report of a 56-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: myasthenia gravis, who was treated with Imuran (dosage: NA, start time:
Jun 14, 2012), combined with: NA. and developed a serious reaction and side effect(s): Migraine, Nausea, Contusion, Gastrointestinal Pain, Pharyngeal Haemorrhage, Tremor, Chills, Heart Rate Increased, Hyperhidrosis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Imuran treatment in female patients, resulting in Migraine side effect.
Imuran Side Effect Report#8814120
Acute Myeloid Leukaemia
This report suggests a potential Imuran Acute Myeloid Leukaemia side effect(s) that can have serious consequences. A female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: crohn^s disease and used Imuran (dosage: NA) starting
Nov 03, 2010. After starting Imuran the patient began experiencing various side effects, including: Acute Myeloid LeukaemiaAdditional drugs used concurrently:
  • Pentaza
  • Vitamin D
  • Multi-vitamin
  • Iron
The patient was hospitalized and became disabled. Although Imuran demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Acute Myeloid Leukaemia, may still occur.
Imuran Side Effect Report#8783876
Pancreatitis
This Pancreatitis problem was reported by a consumer or non-health professional from US. A 50-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Jun 06, 2012 this consumer started treatment with Imuran (dosage: NA). The following drugs were being taken at the same time: NA. When using Imuran, the patient experienced the following unwanted symptoms/side effects: PancreatitisThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Pancreatitis, may become evident only after a product is in use by the general population.
Imuran Side Effect Report#8714613
Dyspnoea, Chest Discomfort, Hypersensitivity, Body Temperature Increased, Infusion Related Reaction, Urticaria, Flushing, Wheezing, Bronchospasm
This Dyspnoea side effect was reported by a health professional from AU. A 28-year-old female patient (weight:NA) experienced the following symptoms/conditions: crohn^s disease,arthralgia.The patient was prescribed Imuran (drug dosage: NA), which was initiated on
Jul 10, 2012. Concurrently used drugs:
  • Sulfasalazine
  • Remicade (Dose 3)
  • Remicade
  • Remicade
  • Remicade
  • Hydrocortisone
  • Fexofenadine
  • Azathioprine
.After starting to take Imuran the consumer reported adverse symptoms, such as: Dyspnoea, Chest Discomfort, Hypersensitivity, Body Temperature Increased, Infusion Related Reaction, Urticaria, Flushing, Wheezing, BronchospasmThese side effects may potentially be related to Imuran.
Imuran Side Effect Report#8479063-2
Concussion, Fall
This is a report of a male patient (weight: NA) from Canada, suffering from the following health symptoms/conditions: NA, who was treated with Imuran (dosage: NA, start time:
Aug 13, 2010), combined with:
  • Remicade (Dose: Once Every 7 To 8 Weeks)
  • Ativan
  • Remicade (Dose: Once Every 7 To 8 Weeks)
  • Asacol
and developed a serious reaction and side effect(s): Concussion, Fall after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Imuran treatment in male patients, resulting in Concussion side effect.


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The appearance of Imuran on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

What are common Imuran Side Effects for Women?

Women Side EffectsReports
Diarrhoea 23
Injection Site Pain 23
Fatigue 21
Arthralgia 16
Pain 16
Crohn's Disease 15
Pyrexia 15
Vomiting 15
Abdominal Pain 13
Headache 13

What are common Imuran Side Effects for Men?

Men Side EffectsReports
Anaemia 13
Headache 11
Fatigue 10
Pyrexia 10
Arthralgia 9
Diarrhoea 9
Multi-organ Failure 9
Renal Disorder 8
Abdominal Pain 7
Blood Bilirubin Increased 6

Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Imuran reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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