Common Invanz Side Effects


The most commonly reported Invanz side effects (click to view or check a box to report):

Convulsion (115)
Confusional State (66)
Hallucination (45)
Pyrexia (34)
Death (26)
Grand Mal Convulsion (26)
Delirium (26)
Asthenia (23)
Muscular Weakness (22)
Status Epilepticus (19)
Diarrhoea (18)
Rash (18)
Agitation (16)
Nausea (16)
Mental Status Changes (15)
Fall (15)
Hallucination, Visual (15)
Gait Disturbance (14)
Sepsis (14)
Myoclonus (14)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Invanz Side Effects Reported to FDA



Invanz Side Effect Report#9999162
Vision Blurred
This is a report of a 37-year-old female patient (weight: NA) from CA, suffering from the following health symptoms/conditions: infection,diabetes mellitus, who was treated with Invanz Ertepenem (dosage: Into A Vein, start time: NS), combined with:
  • Lantus (Given Into/under The Skin)
  • Glyburide
and developed a serious reaction and side effect(s): Vision Blurred after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Invanz Ertepenem treatment in female patients, resulting in Vision Blurred side effect.
Invanz Side Effect Report#9980832
Cardiac Arrest, Acute Hepatic Failure
This report suggests a potential Invanze Cardiac Arrest side effect(s) that can have serious consequences. A 81-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: urinary tract infection and used Invanze (dosage: NA) starting
Mar 02, 2014. After starting Invanze the patient began experiencing various side effects, including: Cardiac Arrest, Acute Hepatic FailureAdditional drugs used concurrently: NA. Although Invanze demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Cardiac Arrest, may still occur.
Invanz Side Effect Report#9938713
Eosinophilic Myocarditis, Cardiac Arrest, Hypoxic-ischaemic Encephalopathy, Brain Oedema, Eosinophilic Pneumonia, Alveolitis, Allergic Hepatitis, Bone Marrow Eosinophilic Leukocyte Count Increased
This Eosinophilic Myocarditis problem was reported by a physician from CH. A 53-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: pneumonia,multiple injuries,cardiovascular disorder,delirium. On
Nov 16, 2013 this consumer started treatment with Invanz (dosage: 1 G, Bid). The following drugs were being taken at the same time:
  • Augmentin (2.2 G, Tid)
  • Lasix (furosemide) (1 Df, Qd)
  • Haldol (1 Df, Qd)
  • Seroquel (1 Df, Qd)
  • Fragmin (5000 Iu, Qd)
  • Morphine Sulfate
  • Novalgin (dipyrone)
  • Temesta
When using Invanz, the patient experienced the following unwanted symptoms/side effects: Eosinophilic Myocarditis, Cardiac Arrest, Hypoxic-ischaemic Encephalopathy, Brain Oedema, Eosinophilic Pneumonia, Alveolitis, Allergic Hepatitis, Bone Marrow Eosinophilic Leukocyte Count IncreasedAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Eosinophilic Myocarditis, may become evident only after a product is in use by the general population.
Invanz Side Effect Report#9937424
Skin Lesion, Wound
This Skin Lesion side effect was reported by a physician from US. A 29-year-old male patient (weight:NA) experienced the following symptoms/conditions: wound.The patient was prescribed Invanz (drug dosage: 1 G, Qd), which was initiated on 201312. Concurrently used drugs:
  • Ferrous Sulfate
  • Dilaudid
  • Lortab
  • Carvedilol
  • Ibuprofen
  • Piroxicam
.After starting to take Invanz the consumer reported adverse symptoms, such as: Skin Lesion, WoundThese side effects may potentially be related to Invanz.
Invanz Side Effect Report#9919225
Arthralgia, Urticaria
This is a report of a 50-year-old male patient (weight: NA) from FR, suffering from the following health symptoms/conditions: urinary tract infection, who was treated with Invanz (dosage: 1 G, Qd, start time:
Jan 29, 2014), combined with: NA. and developed a serious reaction and side effect(s): Arthralgia, Urticaria after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Invanz treatment in male patients, resulting in Arthralgia side effect. The patient was hospitalized.
Invanz Side Effect Report#9915809
Myalgia
This report suggests a potential Invanz Myalgia side effect(s) that can have serious consequences. A 59-year-old male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: lung infection and used Invanz (dosage: Unk) starting
Jan 24, 2014. After starting Invanz the patient began experiencing various side effects, including: MyalgiaAdditional drugs used concurrently:
  • Fentanyl
  • Oxycodone
  • Cyclobenzaprine Hydrochloride
  • Omeprazole
  • Trazodone Hydrochloride
  • Culturelle (lactobacillus Rhamnosus)
Although Invanz demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Myalgia, may still occur.
Invanz Side Effect Report#9899542
White Blood Cell Count Increased, No Therapeutic Response
This White Blood Cell Count Increased problem was reported by a consumer or non-health professional from US. A 25-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: infection,colonic abscess. On 2014 this consumer started treatment with Invanz (dosage: 1 G, 1 Standard Dose Of 1). The following drugs were being taken at the same time: NA. When using Invanz, the patient experienced the following unwanted symptoms/side effects: White Blood Cell Count Increased, No Therapeutic ResponseAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as White Blood Cell Count Increased, may become evident only after a product is in use by the general population.
Invanz Side Effect Report#9893268
Loss Of Consciousness, Convulsion
This Loss Of Consciousness side effect was reported by a consumer or non-health professional from US. A 20-year-old male patient (weight:NA) experienced the following symptoms/conditions: infection.The patient was prescribed Invanz (drug dosage: 1 G, Qd, Infused Over A 30 Minute Time Frame, Invanz Vial With Threaded Port (ea)), which was initiated on
Jan 23, 2014. Concurrently used drugs: NA..After starting to take Invanz the consumer reported adverse symptoms, such as: Loss Of Consciousness, ConvulsionThese side effects may potentially be related to Invanz.
Invanz Side Effect Report#9879848
Dyspepsia, Decreased Appetite
This is a report of a 57-year-old male patient (weight: NA) from US, suffering from the following health symptoms/conditions: infection, who was treated with Invanz (dosage: 1 G, Qd, start time:
Nov 14, 2013), combined with:
  • Carvedilol
  • Furosemide
  • Spironolactone
  • Lisinopril
  • Potassium Chloride
  • Neurontin
  • Percocet
and developed a serious reaction and side effect(s): Dyspepsia, Decreased Appetite after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Invanz treatment in male patients, resulting in Dyspepsia side effect.
Invanz Side Effect Report#9879506
Anxiety, Dyspnoea
This report suggests a potential Invanz Anxiety side effect(s) that can have serious consequences. A 30-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: post procedural infection and used Invanz (dosage: Total Daily Dose: 1g) starting
Jan 25, 2014. After starting Invanz the patient began experiencing various side effects, including: Anxiety, DyspnoeaAdditional drugs used concurrently:
  • Daptomycin (Total Daily Dose: 400 Mg)
Although Invanz demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Anxiety, may still occur.
Invanz Side Effect Report#9869878
Epilepsy, Dry Mouth
This Epilepsy problem was reported by a consumer or non-health professional from FR. A male patient (weight: NA) was diagnosed with the following symptoms/conditions: urinary tract infection. On
Jan 14, 2014 this consumer started treatment with Invanz (dosage: Unk). The following drugs were being taken at the same time:
  • Depakine
  • Epitomax
  • Rufinamide
When using Invanz, the patient experienced the following unwanted symptoms/side effects: Epilepsy, Dry MouthAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Epilepsy, may become evident only after a product is in use by the general population.
Invanz Side Effect Report#9847836
Dehydration, Muscular Weakness, Fatigue
This Dehydration side effect was reported by a physician from US. A 94-year-old female patient (weight:NA) experienced the following symptoms/conditions: arthritis bacterial.The patient was prescribed Invanz (drug dosage: 1 G, Qd), which was initiated on
Jan 17, 2014. Concurrently used drugs: NA..After starting to take Invanz the consumer reported adverse symptoms, such as: Dehydration, Muscular Weakness, FatigueThese side effects may potentially be related to Invanz. The patient was hospitalized and became disabled.
Invanz Side Effect Report#9829695
Atrioventricular Block
This is a report of a 43-year-old male patient (weight: NA) from FR, suffering from the following health symptoms/conditions: NA, who was treated with Invanz (dosage: Unk, start time:
Nov 09, 2013), combined with:
  • Cancidas (Unk)
  • Seropram (Unk)
  • Piperacillin Sodium (+) Tazobactam Sodium (Unk)
  • Triflucan (Unk)
and developed a serious reaction and side effect(s): Atrioventricular Block after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Invanz treatment in male patients, resulting in Atrioventricular Block side effect.
Invanz Side Effect Report#9790115
Rash Maculo-papular, Blister
This report suggests a potential Invanz Rash Maculo-papular side effect(s) that can have serious consequences. A 64-year-old male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: cellulitis and used Invanz (dosage: NA) starting NS. After starting Invanz the patient began experiencing various side effects, including: Rash Maculo-papular, BlisterAdditional drugs used concurrently: NA.The patient was hospitalized. Although Invanz demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Rash Maculo-papular, may still occur.
Invanz Side Effect Report#9780883
Epilepsy, Confusional State
This Epilepsy problem was reported by a physician from CH. A 61-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: urinary tract infection,hiv infection. On
Nov 09, 2013 this consumer started treatment with Invanz (dosage: 1 G, Qd). The following drugs were being taken at the same time:
  • Ziagen (Once Daily)
  • Nexium (Daily)
  • Intelence (Daily)
  • Aprovel (150 Mg, Qd)
  • Lamivudine (300 Mg, Qd)
When using Invanz, the patient experienced the following unwanted symptoms/side effects: Epilepsy, Confusional StateAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Epilepsy, may become evident only after a product is in use by the general population.
Invanz Side Effect Report#9777600
Inflammation, Debridement, Wound, Hypersensitivity, Erythema
This Inflammation side effect was reported by a consumer or non-health professional from ZA. A 55-year-old male patient (weight:NA) experienced the following symptoms/conditions: infection,sepsis.The patient was prescribed Invanz (drug dosage: Total Dialy Dose: 1 Gram), which was initiated on
Nov 29, 2013. Concurrently used drugs: NA..After starting to take Invanz the consumer reported adverse symptoms, such as: Inflammation, Debridement, Wound, Hypersensitivity, ErythemaThese side effects may potentially be related to Invanz.
Invanz Side Effect Report#9776269
Dysbacteriosis, Food Intolerance, Pain In Extremity
This is a report of a 58-year-old male patient (weight: NA) from US, suffering from the following health symptoms/conditions: urinary tract infection, who was treated with Invanz (dosage: Unk, start time: 201310), combined with: NA. and developed a serious reaction and side effect(s): Dysbacteriosis, Food Intolerance, Pain In Extremity after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Invanz treatment in male patients, resulting in Dysbacteriosis side effect.
Invanz Side Effect Report#9754530
Delirium, Convulsion, Immobile, Confusional State
This report suggests a potential Invanz Delirium side effect(s) that can have serious consequences. A 91-year-old female patient (weight: NA) from CA was diagnosed with the following symptoms/conditions: osteitis and used Invanz (dosage: 1 G, Q24h) starting
Sep 05, 2013. After starting Invanz the patient began experiencing various side effects, including: Delirium, Convulsion, Immobile, Confusional StateAdditional drugs used concurrently:
  • Lyrica
  • Celexa
The patient was hospitalized. Although Invanz demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Delirium, may still occur.
Invanz Side Effect Report#9738727
Tooth Discolouration
This Tooth Discolouration problem was reported by a health professional from FR. A 74-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: urinary tract infection bacterial. On
Jul 22, 2013 this consumer started treatment with Invanz (dosage: 1 G, Qd). The following drugs were being taken at the same time: NA. When using Invanz, the patient experienced the following unwanted symptoms/side effects: Tooth DiscolourationAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Tooth Discolouration, may become evident only after a product is in use by the general population.
Invanz Side Effect Report#9729626
Hepatitis Acute
This Hepatitis Acute side effect was reported by a health professional from ES. A 47-year-old male patient (weight:NA) experienced the following symptoms/conditions: cellulitis.The patient was prescribed Invanz (drug dosage: 1 Gr, Once Daily), which was initiated on
Jul 06, 2012. Concurrently used drugs: NA..After starting to take Invanz the consumer reported adverse symptoms, such as: Hepatitis AcuteThese side effects may potentially be related to Invanz. The patient was hospitalized.
Invanz Side Effect Report#9728288
Cholestasis
This is a report of a 80-year-old female patient (weight: NA) from ES, suffering from the following health symptoms/conditions: urinary tract infection, who was treated with Invanz (dosage: NA, start time:
Apr 05, 2013), combined with:
  • Trazodone Hydrochloride
  • Gentamicin
  • Alprazolam
  • Clopidogrel
  • Fluoxetine
  • Furosemide
and developed a serious reaction and side effect(s): Cholestasis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Invanz treatment in female patients, resulting in Cholestasis side effect.
Invanz Side Effect Report#9721429
Dystonia
This report suggests a potential Invanz Dystonia side effect(s) that can have serious consequences. A 91-year-old male patient (weight: NA) from ES was diagnosed with the following symptoms/conditions: urinary tract infection and used Invanz (dosage: NA) starting
Oct 31, 2013. After starting Invanz the patient began experiencing various side effects, including: DystoniaAdditional drugs used concurrently: NA.The patient was hospitalized. Although Invanz demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Dystonia, may still occur.
Invanz Side Effect Report#9720030
Eosinophil Count Increased, Pyrexia
This Eosinophil Count Increased problem was reported by a pharmacist from CH. A 58-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: pneumonia. On
Aug 29, 2012 this consumer started treatment with Invanz (dosage: 1 G, Qd, Formulation: Vial). The following drugs were being taken at the same time:
  • Metoprolol (200 Mg, Qd)
  • Lisinopril (20 Mg, Qd)
  • Amlodipine (10 Mg, Qd)
  • Oxcarbazepine (600 Mg, Bid)
  • Atorvastatin (80 Mg, Qd)
  • Dalteparin Sodium (5000 Iu, Qd)
  • Esomeprazole Magnesium (20 Mg, Qd)
  • Levocetirizine (5 Mg, Qd)
When using Invanz, the patient experienced the following unwanted symptoms/side effects: Eosinophil Count Increased, PyrexiaThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Eosinophil Count Increased, may become evident only after a product is in use by the general population.
Invanz Side Effect Report#9719445
Renal Failure, Blood Creatinine Increased, Blood Urea Increased
This Renal Failure side effect was reported by a physician from US. A 71-year-old male patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Invanz (drug dosage: Strength 1 Gm, Renal Dose), which was initiated on NS. Concurrently used drugs: NA..After starting to take Invanz the consumer reported adverse symptoms, such as: Renal Failure, Blood Creatinine Increased, Blood Urea IncreasedThese side effects may potentially be related to Invanz. The patient was hospitalized.
Invanz Side Effect Report#9714544
Face Oedema
This is a report of a 35-year-old female patient (weight: NA) from PT, suffering from the following health symptoms/conditions: cholangitis, who was treated with Invanz (dosage: 1 G, Qd, start time:
Nov 15, 2013), combined with: NA. and developed a serious reaction and side effect(s): Face Oedema after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Invanz treatment in female patients, resulting in Face Oedema side effect.


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The appearance of Invanz on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

What are common Invanz Side Effects for Women?

Women Side Effects Reports
Convulsion 48
Confusional State 32
Hallucination 27
Asthenia 19
Delirium 16
Pyrexia 14
Muscular Weakness 13
Chest Pain 12
Diarrhoea 12
Nausea 12

What are common Invanz Side Effects for Men?

Men Side Effects Reports
Convulsion 65
Confusional State 34
Pyrexia 20
Grand Mal Convulsion 18
Hallucination 18
Death 14
Agitation 13
Rash 12
Epilepsy 11
Fall 11

Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Invanz reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

    Discuss Invanz Side Effects

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    How Effective is Invanz for You?

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    Invanz Safety Alerts, Active Ingredients, Usage Information

    NDC 0006-3843
    Type HUMAN PRESCRIPTION DRUG
    Proprietary Name INVANZ
    Name ertapenem sodium
    Dosage Form INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
    Route INTRAMUSCULAR; INTRAVENOUS
    On market since 20011121
    Labeler Merck Sharp & Dohme Corp.
    Active Ingredient(s) ERTAPENEM SODIUM
    Strength(s) 1
    Unit(s) g/1
    Pharma Class Carbapenems [Chemical/Ingredient],Penem Antibacterial [EPC]

    Invanz Dosage, Warnings, Usage.

    Side Effects reported to FDA: 678

    Invanz safety alerts: 2007

    Reported deaths: 102

    Reported hospitalizations: 474

    Invanz (ertapenem sodium) Injection

    Audience: Infectious disease specialists, hospital administrators and pharmacists, other healthcare professionals

    [Posted 07/05/2007] Merck and FDA informed healthcare professionals that 3 lots of Invanz (0803930, 0803940, and 0803950), a product indicated for the treatment of patients with moderate to severe infections caused by susceptible isolates of the designated microorganisms, were recalled. The product was recalled because of two incidents of finding broken glass pieces in the reconstituted solution for injection. Healthcare professionals are advised to immediately stop dispensing all products from the three lots specified above. No other lots are affected by this recall.

    [July 02, 2007 - Dear Healthcare Professional Letter - Merck]

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