Isorbide Side Effects

Common Isorbide Side Effects

The most commonly reported Isorbide side effects (click to view or check a box to report):

Blood Triglycerides Increased (1)
Blood Sodium Decreased (1)
Blood Chloride Decreased (1)
Toxic Epidermal Necrolysis (1)
Blood Urea Increased (1)
Cardiac Failure Acute (1)
Pruritus (1)
Neutropenic Sepsis (1)
International Normalised Ratio Decreased (1)
Cardiac Failure Congestive (1)
Atrial Natriuretic Peptide Increased (1)

If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

Isorbide Side Effects Reported to FDA

The following Isorbide reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

The appearance of Isorbide on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.
Neutropenic Sepsis, Toxic Epidermal Necrolysis
on Sep 23, 2011 Female from UNITED KINGDOM , 57 years of age, weighting 125.7 lb, was treated with Isorbide. Directly after, patient experienced the unwanted or unexpected Isorbide side effects: neutropenic sepsis, toxic epidermal necrolysis. Isorbide dosage: N/A.
Associated medications used:
  • Ursodiol
  • Diazepam
  • Dothiepin Hydrochloride
  • Furosemide
  • Simvastatin
  • Warfarin Sodium
  • Gemcitabine Hydrochloride
  • Bisoprolol
Patient was hospitalized.

Pruritus, Blood Triglycerides Increased
Patient was taking Isorbide. Patient felt the following Isorbide side effects: pruritus, blood triglycerides increased on Dec 28, 2010 from UNITED STATES Additional patient health information: Male , weighting 285.3 lb, . Isorbide dosage: N/A.
Multiple prescriptions taken:
  • Cozaar
  • Coumadin
  • Aspirin (In The Morning)
  • Folic Acid
  • Niaspan (At Bedtime)
  • Metoprolol Tartrate

International Normalised Ratio Decreased
Adverse event was reported on Nov 05, 2010 by a Female taking Isorbide (Dosage: N/A) . Location: UNITED STATES , 77 years of age, weighting 178.6 lb, After Isorbide was administered, patient encountered several Isorbide side effects: international normalised ratio decreased.
Multiple concurrent drugs taken:
  • Omeprazole
  • Centrum Silver
  • Nifedipine
  • Vitamin B-12 (Pill And Monthly Shot)
  • Novolog (1 D.f:70/30 Units Not Specified)
  • Lorazepam
  • Lisinopril
  • Warfarin Sodium

Atrial Natriuretic Peptide Increased, Blood Chloride Decreased, Blood Sodium Decreased, Blood Urea Increased, Cardiac Failure Acute, Cardiac Failure Congestive
on Sep 26, 2006 Female from UNITED STATES , 75 years of age, weighting 133.0 lb, was diagnosed with and was treated with Isorbide. Directly after, patient experienced the unwanted or unexpected Isorbide side effects: atrial natriuretic peptide increased, blood chloride decreased, blood sodium decreased, blood urea increased, cardiac failure acute, cardiac failure congestive. Isorbide dosage: 20 Mg Tid Po. Patient was hospitalized.

Keep Track of Side Effects

Note Your Observations

It is really important to keep of your symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:


    Side Effects


    Date & Time

    Other Medicine(s) or Treatment(s)





    Scale: 1 = very mild to 10 = very bad

    Track Online

  • User Sign In
  • Register to track your side effects

  • You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Discuss Isorbide Side Effects

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    Safety Alerts, Active Ingredients, Usage Information

    More About Isorbide

    Side Effects reported to FDA: 4

    Isorbide safety alerts: No

    Reported deaths: 1

    Reported hospitalizations: 2

    Latest Isorbide clinical trials