LAPATINIB Side Effects

7022854-5 | Neutropenia
on Sep 28, 2010 Female patient from POLAND , weighting 134.5 lb, was diagnosed with hyperthyroidism and was treated with Lapatinib (View Usage). Patient experienced the following unwanted or unexpected effects: neutropenia. Lapatinib dosage: 1250mg Per Day. During the same period patient was treated with CAPECITABINE (2000mgm2 Cyclic) (View Capecitabine Review and Capecitabine Label ), LETROX (50mg Per Day) (View Letrox Review and Letrox Label ), NIMESIL (View Nimesil Review and Nimesil Label ).

7022853-3 | Pneumonia
Patient was taking Lapatinib (View Usage). Patient had the following side effects: pneumonia (What is pneumonia?) on Sep 28, 2010 from JAPAN Additional patient health information: Male patient , weighting 123.7 lb, was diagnosed with gastric cancer and. Lapatinib dosage: 1500mg Per Day. During the same period patient was treated with PACLITAXEL (80mgm2 Cyclic) (View Paclitaxel Review and Paclitaxel Label ). Patient was hospitalized.

7022822-3 | Dehydration, Hyponatraemia, Hypotension, Multi-organ Failure, Neutropenia, Sepsis
Adverse event was reported on Sep 17, 2010 by a Male patient taking Lapatinib (View Usage) (Dosage: 1250mg Per Day) was diagnosed with gastric cancer, vomiting and. Location: INDIA , weighting 85.98 lb, After Lapatinib was administered, patient had the following side effects: dehydration, hyponatraemia, hypotension, multi-organ failure, neutropenia, sepsis (What is sepsis?). During the same period patient was treated with CAPECITABINE (1700mgm2 Twice Per Day) (View Capecitabine Review and Capecitabine Label ), OXALIPLATIN (130mgm2 Cyclic) (View Oxaliplatin Review and Oxaliplatin Label ), MULTI VITAMIN (View Multi-vitamin Review and Multi-vitamin Label ), OROFER (View Orofer Review and Orofer Label ), ONDANSETRON (8mg Three Times Per Day) (View Ondansetron Review and Ondansetron Label ). Patient was hospitalized.

7022759-X | Diarrhoea, Gastrointestinal Infection, Vomiting
on Sep 27, 2010 Female patient from UNITED STATES , 53 years of age, weighting 172.0 lb, was diagnosed with breast cancer (What is breast cancer?) and was treated with Lapatinib (View Usage). Patient experienced the following unwanted or unexpected effects: diarrhoea, gastrointestinal infection, vomiting. Lapatinib dosage: 750mg Per Day. During the same period patient was treated with TRASTUZUMAB (4mgk Weekly) (View Trastuzumab Review and Trastuzumab Label ), DOCETAXEL (75mgm2 Every 3 Weeks) (View Docetaxel Review and Docetaxel Label ), CARBOPLATIN (View Carboplatin Review and Carboplatin Label ), IV FLUIDS (View Iv Fluids Review and Iv Fluids Label ). Patient was hospitalized.


7020660-9 | Neutropenia
on Sep 28, 2010 Female patient from KOREA, REPUBLIC OF , weighting 116.8 lb, was diagnosed with gastric cancer and was treated with Lapatinib (View Usage). Patient had the following side effects: neutropenia. Lapatinib dosage: 1500mg Per Day. During the same period patient was treated with PACLITAXEL (80mgm2 Cyclic) (View Paclitaxel Review and Paclitaxel Label ). Patient was hospitalized.

7020659-2 | Helicobacter Gastritis
Patient was taking Lapatinib (View Usage). After Lapatinib was administered, patient had the following side effects: helicobacter gastritis on Sep 27, 2010 from GERMANY Additional patient health information: Female patient , weighting 149.9 lb, . Lapatinib dosage: 1250mg Per Day. During the same period patient was treated with CAPECITABINE (2000mgm2 Cyclic) (View Capecitabine Review and Capecitabine Label ). Patient was hospitalized.

7020642-7 | Chills, Cough, Productive Cough, Pyrexia, Rhinitis, Upper Respiratory Tract Infection
Adverse event was reported on Sep 21, 2010 by a Female patient taking Lapatinib (View Usage) (Dosage: 750mg Per Day) was diagnosed with breast cancer (What is breast cancer?), hypertension, osteoporosis (What is osteoporosis?), ocular discomfort and. Location: HONG KONG , weighting 97.00 lb, Patient experienced the following unwanted or unexpected effects: chills, cough, productive cough, pyrexia, rhinitis, upper respiratory tract infection. During the same period patient was treated with AMLODIPINE (5mg Per Day) (View Amlodipine Review and Amlodipine Label ), ACETYLCYSTEINE (300mg Per Day) (View Acetylcysteine Review and Acetylcysteine Label ), NAVELBINE (80mg Per Day) (View Navelbine Review and Navelbine Label ), CALPEROS (4tab Per Day) (View Calperos Review and Calperos Label ), FAMOTIDINE (View Famotidine Review and Famotidine Label ), LISINOPRIL (View Lisinopril Review and Lisinopril Label ), HYPROMELLOSE (View Hypromellose Review and Hypromellose Label ). Patient was hospitalized.

7020628-2 | Ileus
on Sep 20, 2010 Female patient from BELGIUM , weighting 154.3 lb, was diagnosed with breast cancer (What is breast cancer?), arthralgia, insomnia and was treated with Lapatinib (View Usage). Patient had the following side effects: ileus. Lapatinib dosage: 1500mg Per Day. During the same period patient was treated with ACETAMINOPHEN (500mg As Required) (View Acetaminophen Review and Acetaminophen Label ), LORMETAZEPAM (1mg Per Day) (View Lormetazepam Review and Lormetazepam Label ). Patient was hospitalized.

7020627-0 | Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Blood Alkaline Phosphatase Increased, Gamma-glutamyltransferase Increased, Hepatic Enzyme Increased
on Sep 21, 2010 Female patient from IRELAND , weighting 159.4 lb, was diagnosed with breast cancer (What is breast cancer?) and was treated with Lapatinib (View Usage). After Lapatinib was administered, patient had the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, gamma-glutamyltransferase increased, hepatic enzyme increased. Lapatinib dosage: 1000mg Per Day. During the same period patient was treated with PACLITAXEL (80mgm2 Per Day) (View Paclitaxel Review and Paclitaxel Label ), TRASTUZUMAB (View Trastuzumab Review and Trastuzumab Label ).

7019132-7 | Chills, Cough, Productive Cough, Pyrexia, Rhinitis, Upper Respiratory Tract Infection
Patient was taking Lapatinib (View Usage). Patient experienced the following unwanted or unexpected effects: chills, cough, productive cough, pyrexia, rhinitis, upper respiratory tract infection on Sep 21, 2010 from HONG KONG Additional patient health information: Female patient , weighting 97.00 lb, was diagnosed with breast cancer (What is breast cancer?), hypertension, osteoporosis (What is osteoporosis?), ocular discomfort and. Lapatinib dosage: 750mg Per Day. During the same period patient was treated with AMLODIPINE (5mg Per Day) (View Amlodipine Review and Amlodipine Label ), ACETYLCYSTEINE (300mg Per Day) (View Acetylcysteine Review and Acetylcysteine Label ), NAVELBINE (80mg Per Day) (View Navelbine Review and Navelbine Label ), CALPEROS (4tab Per Day) (View Calperos Review and Calperos Label ), FAMOTIDINE (View Famotidine Review and Famotidine Label ), LISINOPRIL (View Lisinopril Review and Lisinopril Label ), HYPROMELLOSE (View Hypromellose Review and Hypromellose Label ). Patient was hospitalized.

7019131-5 | Erythema, Leukopenia, Neutropenia
Adverse event was reported on Sep 24, 2010 by a Female patient taking Lapatinib (View Usage) (Dosage: 1250mg Per Day) was diagnosed with breast cancer (What is breast cancer?) and. Location: GERMANY , weighting 143.3 lb, Patient had the following side effects: erythema, leukopenia, neutropenia. During the same period patient was treated with PACLITAXEL (175mg Every 3 Weeks) (View Paclitaxel Review and Paclitaxel Label ), MYOCET (60mg Every 3 Weeks) (View Myocet Review and Myocet Label ).

7019117-0 | Diarrhoea, Febrile Neutropenia, Stomatitis
on Sep 20, 2010 Female patient from FRANCE , weighting 114.6 lb, was diagnosed with anxiety (What is anxiety?), constipation (What is constipation?), insomnia, depression (What is depression?) and was treated with Lapatinib (View Usage). After Lapatinib was administered, patient had the following side effects: diarrhoea, febrile neutropenia, stomatitis. Lapatinib dosage: 1250mg Per Day. During the same period patient was treated with TAXOTERE (119.25mg Per Day) (View Taxotere Review and Taxotere Label ), SEROPLEX (View Seroplex Review and Seroplex Label ), ZOLPIDEM TARTRATE (View Zolpidem Tartrate Review and Zolpidem Tartrate Label ), IMODIUM (View Imodium Review and Imodium Label ), NORDAZEPAM (View Nordazepam Review and Nordazepam Label ), ESCITALOPRAM (View Escitalopram Review and Escitalopram Label ). Patient was hospitalized.

7019114-5 | Pain In Extremity, Paraesthesia, Polyneuropathy
on Sep 20, 2010 Female patient from DENMARK , weighting 185.2 lb, was diagnosed with breast cancer (What is breast cancer?) and was treated with Lapatinib (View Usage). Patient experienced the following unwanted or unexpected effects: pain in extremity, paraesthesia, polyneuropathy. Lapatinib dosage: 1500mg Per Day. During the same period patient was treated with TAMOXIFEN CITRATE (View Tamoxifen Citrate Review and Tamoxifen Citrate Label ), TAXOTERE (550mg Per Day) (View Taxotere Review and Taxotere Label ), EPIRUBICIN (View Epirubicin Review and Epirubicin Label ), CYCLOPHOSPHAMIDE (View Cyclophosphamide Review and Cyclophosphamide Label ). Patient was hospitalized.

7016541-7 | Fatigue, Hypokalaemia
Patient was taking Lapatinib (View Usage). Patient had the following side effects: fatigue, hypokalaemia on Sep 22, 2010 from UNITED STATES Additional patient health information: Female patient , 57 years of age, weighting 114.6 lb, was diagnosed with breast cancer (What is breast cancer?) and. Lapatinib dosage: 750mg Per Day. During the same period patient was treated with DOCETAXEL (75mgm2 Every 3 Weeks) (View Docetaxel Review and Docetaxel Label ), CARBOPLATIN (View Carboplatin Review and Carboplatin Label ), TRASTUZUMAB (View Trastuzumab Review and Trastuzumab Label ).

7012845-2 | Pneumonia
Adverse event was reported on Sep 22, 2010 by a Male patient taking Lapatinib (View Usage) (Dosage: 1500mg Per Day) was diagnosed with gastric cancer and. Location: JAPAN , weighting 123.7 lb, After Lapatinib was administered, patient had the following side effects: pneumonia (What is pneumonia?). During the same period patient was treated with PACLITAXEL (80mgm2 Cyclic) (View Paclitaxel Review and Paclitaxel Label ). Patient was hospitalized.

7012840-3 | Leukopenia, Neutropenia
on Sep 21, 2010 Female patient from GERMANY , weighting 158.7 lb, was diagnosed with breast cancer (What is breast cancer?) and was treated with Lapatinib (View Usage). Patient experienced the following unwanted or unexpected effects: leukopenia, neutropenia. Lapatinib dosage: 1250mg Per Day. During the same period patient was treated with PACLITAXEL (175mg Every 3 Weeks) (View Paclitaxel Review and Paclitaxel Label ), MYOCET (60mg Every 3 Weeks) (View Myocet Review and Myocet Label ).

7012796-3 | Cough, Dyspnoea, Pleural Effusion
on Sep 16, 2010 Female patient from TAIWAN, PROVINCE OF CHINA , weighting 116.8 lb, was diagnosed with chest pain (What is chest pain?) and was treated with Lapatinib (View Usage). Patient had the following side effects: cough, dyspnoea, pleural effusion. Lapatinib dosage: 1250mg Per Day. During the same period patient was treated with CAPECITABINE (3000mgm2 Per Day) (View Capecitabine Review and Capecitabine Label ), ACETAMINOPHEN (500mg Four Times Per Day) (View Acetaminophen Review and Acetaminophen Label ), TRAMADOL (100mg Four Times Per Day) (View Tramadol Review and Tramadol Label ). Patient was hospitalized.

7012795-1 | Cardiac Failure Congestive, Chest Pain, Dyspnoea, Oedema
Patient was taking Lapatinib (View Usage). After Lapatinib was administered, patient had the following side effects: cardiac failure congestive, chest pain (What is chest pain?), dyspnoea, oedema on Sep 17, 2010 from BELGIUM Additional patient health information: Female patient , weighting 187.4 lb, was diagnosed with breast cancer (What is breast cancer?) and. Lapatinib dosage: 1000mg Per Day. During the same period patient was treated with TRASTUZUMAB (View Trastuzumab Review and Trastuzumab Label ), EPIRUBICIN (400mgm2 Per Day) (View Epirubicin Review and Epirubicin Label ), LETROZOLE (2.5mg Per Day) (View Letrozole Review and Letrozole Label ).

7012776-8 | Abdominal Pain, Diarrhoea, Nausea
Adverse event was reported on Sep 21, 2010 by a Female patient taking Lapatinib (View Usage) (Dosage: 1000mg Per Day) . Location: UNITED STATES , 59 years of age, weighting 117.1 lb, Patient experienced the following unwanted or unexpected effects: abdominal pain (What is abdominal pain?), diarrhoea, nausea (What is nausea?). During the same period patient was treated with PACLITAXEL (70mgm2 Cyclic) (View Paclitaxel Review and Paclitaxel Label ), TRASTUZUMAB (4mgk Weekly) (View Trastuzumab Review and Trastuzumab Label ). Patient was hospitalized.

7009759-0 | Dizziness, Hypotension, Neutropenia
on Sep 15, 2010 Female patient from SOUTH AFRICA , weighting 158.7 lb, was diagnosed with breast cancer metastatic, hypertension, prophylaxis, back pain (What is back pain?), hypothyroidism and was treated with Lapatinib (View Usage). Patient had the following side effects: dizziness (What is dizziness?), hypotension, neutropenia. Lapatinib dosage: . During the same period patient was treated with DIOVAN HCT (View Diovan Hct Review and Diovan Hct Label ), ASPIRIN (View Aspirin Review and Aspirin Label ), ACETAMINOPHEN (View Acetaminophen Review and Acetaminophen Label ), LEVOTHYROXINE SODIUM (View Levothyroxine Sodium Review and Levothyroxine Sodium Label ), CAPECITABINE (1450 Mg Twice Daily Days 1-14 Of Cycle) (View Capecitabine Review and Capecitabine Label ). Patient was hospitalized.

7008391-2 | Hypokalaemia, Leukopenia, Pyrexia
on Sep 14, 2010 Male patient from NETHERLANDS , weighting 156.5 lb, was diagnosed with gastric cancer and was treated with Lapatinib (View Usage). After Lapatinib was administered, patient had the following side effects: hypokalaemia, leukopenia, pyrexia. Lapatinib dosage: 1250mg Per Day. During the same period patient was treated with OXALIPLATIN (240mg Every 3 Weeks) (View Oxaliplatin Review and Oxaliplatin Label ), CAPECITABINE (1650mg Twice Per Day) (View Capecitabine Review and Capecitabine Label ). Patient was hospitalized.

7008387-0 | Cardiac Failure Congestive, Diarrhoea, Pulmonary Oedema, Respiratory Arrest, Sepsis, Vomiting
Patient was taking Lapatinib (View Usage). Patient experienced the following unwanted or unexpected effects: cardiac failure congestive, diarrhoea, pulmonary oedema, respiratory arrest, sepsis (What is sepsis?), vomiting on Sep 14, 2010 from AUSTRALIA Additional patient health information: Female patient , weighting 124.8 lb, . Lapatinib dosage: 750mg Per Day. During the same period patient was treated with PACLITAXEL (105mg Weekly) (View Paclitaxel Review and Paclitaxel Label ). Patient was hospitalized.

7002000-4 | Thrombocytopenia
Adverse event was reported on Sep 17, 2010 by a Male patient taking Lapatinib (View Usage) (Dosage: 1250mg Per Day) was diagnosed with gastric cancer and. Location: TAIWAN, PROVINCE OF CHINA , weighting 152.1 lb, Patient had the following side effects: thrombocytopenia. During the same period patient was treated with OXALIPLATIN (130mgm2 Cyclic) (View Oxaliplatin Review and Oxaliplatin Label ), CAPECITABINE (1700mgm2 Twice Per Day) (View Capecitabine Review and Capecitabine Label ).

7001997-6 | Neutropenia, Vomiting
on Sep 13, 2010 Female patient from PHILIPPINES , weighting 121.5 lb, was diagnosed with breast cancer (What is breast cancer?) and was treated with Lapatinib (View Usage). After Lapatinib was administered, patient had the following side effects: neutropenia, vomiting. Lapatinib dosage: . During the same period patient was treated with DOCETAXEL (View Docetaxel Review and Docetaxel Label ), CIPRO (500mg Twice Per Day) (View Cipro Review and Cipro Label ), DOLO NEUROBION (500mg Three Times Per Day) (View Dolo-neurobion Review and Dolo-neurobion Label ).

7001996-4 | Anaemia, Klebsiella Test Positive, Pyrexia, Urinary Tract Infection
on Sep 14, 2010 Male patient from DENMARK , weighting 147.0 lb, was diagnosed with transitional cell cancer of the renal pelvis and ureter, blood cholesterol increased, dyspepsia and was treated with Lapatinib (View Usage). Patient experienced the following unwanted or unexpected effects: anaemia, klebsiella test positive, pyrexia, urinary tract infection (What is urinary tract infection?). Lapatinib dosage: . During the same period patient was treated with CISPLATIN (View Cisplatin Review and Cisplatin Label ), GEMCITABINE (View Gemcitabine Review and Gemcitabine Label ), SIMVASTATIN (View Simvastatin Review and Simvastatin Label ), PANTALOC (View Pantaloc Review and Pantaloc Label ). Patient was hospitalized.

6992888-5 | Pneumonia
Patient was taking Lapatinib (View Usage). Patient had the following side effects: pneumonia (What is pneumonia?) on Sep 16, 2010 from JAPAN Additional patient health information: Male patient , weighting 123.7 lb, was diagnosed with gastric cancer and. Lapatinib dosage: 1500mg Per Day. During the same period patient was treated with PACLITAXEL (80mgm2 Cyclic) (View Paclitaxel Review and Paclitaxel Label ). Patient was hospitalized.

6992887-3 | Neutropenia
Adverse event was reported on Sep 16, 2010 by a Female patient taking Lapatinib (View Usage) (Dosage: 1500mg Per Day) was diagnosed with gastric cancer and. Location: KOREA, REPUBLIC OF , weighting 116.8 lb, After Lapatinib was administered, patient had the following side effects: neutropenia. During the same period patient was treated with PACLITAXEL (80mgm2 Cyclic) (View Paclitaxel Review and Paclitaxel Label ). Patient was hospitalized.

6992885-X | Pyrexia
on Sep 16, 2010 Male patient from KOREA, REPUBLIC OF , weighting 105.4 lb, was diagnosed with gastric cancer and was treated with Lapatinib (View Usage). Patient experienced the following unwanted or unexpected effects: pyrexia. Lapatinib dosage: 1500mg Per Day. During the same period patient was treated with PACLITAXEL (120mg Cyclic) (View Paclitaxel Review and Paclitaxel Label ). Patient was hospitalized.

6992884-8 | Diarrhoea, Febrile Neutropenia
on Sep 15, 2010 Female patient from UNITED STATES , 61 years of age, weighting 237.4 lb, was diagnosed with febrile neutropenia and was treated with Lapatinib (View Usage). Patient had the following side effects: diarrhoea, febrile neutropenia. Lapatinib dosage: 1250mg Per Day. During the same period patient was treated with PACLITAXEL (100mgm2 Cyclic) (View Paclitaxel Review and Paclitaxel Label ), ONDANSETRON HCL (4mg Four Times Per Day) (View Ondansetron Hcl Review and Ondansetron Hcl Label ), MORPHINE (1mg As Required) (View Morphine Review and Morphine Label ), ACETAMINOPHEN (650mg As Required) (View Acetaminophen Review and Acetaminophen Label ), NEUPOGEN (480mcg Single Dose) (View Neupogen Review and Neupogen Label ), DIPHENHYDRAMINE HCL (25mg As Required) (View Diphenhydramine Hcl Review and Diphenhydramine Hcl Label ). Patient was hospitalized.

6992863-0 | Atrial Fibrillation, Dyspnoea, Oedema Peripheral
Patient was taking Lapatinib (View Usage). After Lapatinib was administered, patient had the following side effects: atrial fibrillation (What is atrial fibrillation?), dyspnoea, oedema peripheral on Sep 09, 2010 from GERMANY Additional patient health information: Female patient , weighting 154.3 lb, was diagnosed with breast cancer (What is breast cancer?), arrhythmia (What is arrhythmia?), hypertension and. Lapatinib dosage: 1000mg Per Day. During the same period patient was treated with DOCETAXEL (75mgm2 Every 3 Weeks) (View Docetaxel Review and Docetaxel Label ), TRASTUZUMAB (2mgk Weekly) (View Trastuzumab Review and Trastuzumab Label ), PROPAFENONE HCL (150mg Three Times Per Day) (View Propafenone Hcl Review and Propafenone Hcl Label ), RAMIPRIL (2.5mg Per Day) (View Ramipril Review and Ramipril Label ), ASPIRIN (100mg Per Day) (View Aspirin Review and Aspirin Label ). Patient was hospitalized.

6992850-2 | Ileus
Adverse event was reported on Sep 09, 2010 by a Female patient taking Lapatinib (View Usage) (Dosage: 1500mg Per Day) was diagnosed with breast cancer (What is breast cancer?), arthralgia, insomnia and. Location: BELGIUM , weighting 154.3 lb, Patient experienced the following unwanted or unexpected effects: ileus. During the same period patient was treated with ACETAMINOPHEN (500mg As Required) (View Acetaminophen Review and Acetaminophen Label ), LORMETAZEPAM (1mg Per Day) (View Lormetazepam Review and Lormetazepam Label ).

6992849-6 | Blood Creatine Phosphokinase Decreased, Electrocardiogram Abnormal
on Sep 09, 2010 Female patient from BELGIUM , weighting 138.2 lb, was diagnosed with breast cancer (What is breast cancer?), hypertension and was treated with Lapatinib (View Usage). Patient had the following side effects: blood creatine phosphokinase decreased, electrocardiogram abnormal. Lapatinib dosage: 1500mg Per Day. During the same period patient was treated with TRASTUZUMAB (View Trastuzumab Review and Trastuzumab Label ), TAMOXIFEN CITRATE (20mg Per Day) (View Tamoxifen Citrate Review and Tamoxifen Citrate Label ), BISOPROLOLFUMARAT (View Bisoprololfumarat Review and Bisoprololfumarat Label ), HYDROCHLOROTHIAZIDE (View Hydrochlorothiazide Review and Hydrochlorothiazide Label ). Patient was hospitalized.

6985793-1 | Dizziness, Hypotension, Neutropenia
on Sep 13, 2010 Female patient from SOUTH AFRICA , weighting 158.7 lb, was diagnosed with breast cancer metastatic, hypertension, prophylaxis, back pain (What is back pain?), hypothyroidism and was treated with Lapatinib (View Usage). After Lapatinib was administered, patient had the following side effects: dizziness (What is dizziness?), hypotension, neutropenia. Lapatinib dosage: . During the same period patient was treated with DIOVAN HCT (View Diovan Hct Review and Diovan Hct Label ), ACETYLSALICYLIC ACID (View Acetylsalicylic Acid Review and Acetylsalicylic Acid Label ), ACETAMINOPHEN (View Acetaminophen Review and Acetaminophen Label ), LEVOTHYROXINE SODIUM (View Levothyroxine Sodium Review and Levothyroxine Sodium Label ), CAPECITABINE (1450 Mg Twice Daily Days 1-14 Of Cycle) (View Capecitabine Review and Capecitabine Label ). Patient was hospitalized.

6985516-6 | Pyrexia
Patient was taking Lapatinib (View Usage). Patient experienced the following unwanted or unexpected effects: pyrexia on Sep 14, 2010 from KOREA, REPUBLIC OF Additional patient health information: Male patient , weighting 105.4 lb, was diagnosed with gastric cancer and. Lapatinib dosage: 1500mg Per Day. During the same period patient was treated with PACLITAXEL (120mg Cyclic) (View Paclitaxel Review and Paclitaxel Label ). Patient was hospitalized.

6985485-9 | Asthenia, Diarrhoea, Dizziness, Mucosal Inflammation
Adverse event was reported on Sep 07, 2010 by a Female patient taking Lapatinib (View Usage) (Dosage: 750mg Per Day) was diagnosed with breast cancer (What is breast cancer?) and. Location: KOREA, REPUBLIC OF , weighting 106.9 lb, Patient had the following side effects: asthenia, diarrhoea, dizziness (What is dizziness?), mucosal inflammation. During the same period patient was treated with PACLITAXEL (80mgm2 Weekly) (View Paclitaxel Review and Paclitaxel Label ). Patient was hospitalized.

6985482-3 | Hypokalaemia, Nausea, Pericarditis
on Sep 07, 2010 Female patient from GERMANY , weighting 154.3 lb, was diagnosed with breast cancer (What is breast cancer?) and was treated with Lapatinib (View Usage). After Lapatinib was administered, patient had the following side effects: hypokalaemia, nausea (What is nausea?), pericarditis. Lapatinib dosage: 1000mg Per Day. During the same period patient was treated with DOCETAXEL (171mg Every 3 Weeks) (View Docetaxel Review and Docetaxel Label ), EPIRUBICIN (154mg Every 3 Weeks) (View Epirubicin Review and Epirubicin Label ), CYCLOPHOSPHAMIDE (1026mg Every 3 Weeks) (View Cyclophosphamide Review and Cyclophosphamide Label ). Patient was hospitalized.

6985477-X | Pyrexia, Urinary Tract Infection
on Sep 06, 2010 Female patient from GERMANY , weighting 134.5 lb, was diagnosed with breast cancer (What is breast cancer?) and was treated with Lapatinib (View Usage). Patient experienced the following unwanted or unexpected effects: pyrexia, urinary tract infection (What is urinary tract infection?). Lapatinib dosage: 1000mg Per Day. During the same period patient was treated with DOCETAXEL (100mgm2 Per Day) (View Docetaxel Review and Docetaxel Label ), CYCLOPHOSPHAMIDE (600mgm2 Per Day) (View Cyclophosphamide Review and Cyclophosphamide Label ), FARMORUBICIN (90mgm2 Every 3 Weeks) (View Farmorubicin Review and Farmorubicin Label ). Patient was hospitalized.

6985457-4 | Cardiac Arrest, Cardiac Failure Congestive, Ejection Fraction Decreased, Hypoxic-ischaemic Encephalopathy, Pneumonia, Sepsis
Patient was taking Lapatinib (View Usage). Patient had the following side effects: cardiac arrest (What is cardiac arrest?), cardiac failure congestive, ejection fraction decreased, hypoxic-ischaemic encephalopathy, pneumonia (What is pneumonia?), sepsis (What is sepsis?) on Sep 10, 2010 from CHILE Additional patient health information: Female patient , weighting 158.7 lb, was diagnosed with breast cancer (What is breast cancer?), bronchitis (What is bronchitis?), asthma (What is asthma?) and. Lapatinib dosage: 1000mg Per Day. During the same period patient was treated with TRASTUZUMAB (6mgk Every 3 Weeks) (View Trastuzumab Review and Trastuzumab Label ), BISOPROLOL (2.5mg Per Day) (View Bisoprolol Review and Bisoprolol Label ), SPIRONOLACTONE (25mg Per Day) (View Spironolactone Review and Spironolactone Label ), ALBUTEROL SULFATE AUTOHALER (100mcg Twice Per Day) (View Albuterol Sulfate Autohaler Review and Albuterol Sulfate Autohaler Label ), FLUTICASONE PROPIONATE (View Fluticasone Propionate Review and Fluticasone Propionate Label ), IBUPROFEN (400mg Eight Times Per Day) (View Ibuprofen Review and Ibuprofen Label ), CELEBRA (200mg Twice Per Day) (View Celebra Review and Celebra Label ), HEDERA HELIX (10ml Three Times Per Day) (View Hedera Helix Review and Hedera Helix Label ). Patient was hospitalized.

6985456-2 | Infection
Adverse event was reported on Sep 10, 2010 by a Female patient taking Lapatinib (View Usage) (Dosage: ) was diagnosed with neoplasm and. Location: UNITED STATES , 35 years of age, weighting 193.3 lb, After Lapatinib was administered, patient had the following side effects: infection (What is infection?). Patient was hospitalized.

6979470-0 | Liver Function Test Abnormal
on Sep 10, 2010 Female patient from UNITED STATES , 57 years of age, was treated with Lapatinib (View Usage). Patient experienced the following unwanted or unexpected effects: liver function test abnormal. Lapatinib dosage: Daily Po.

6978717-4 | Device Related Infection, Injection Site Reaction
on Sep 03, 2010 Female patient from GERMANY , weighting 167.6 lb, was diagnosed with prophylaxis and was treated with Lapatinib (View Usage). Patient had the following side effects: device related infection, injection site reaction. Lapatinib dosage: . During the same period patient was treated with PACLITAXEL (View Paclitaxel Review and Paclitaxel Label ), IBUPROFEN (View Ibuprofen Review and Ibuprofen Label ), LOPERAMIDE (View Loperamide Review and Loperamide Label ), RANITIDINE (View Ranitidine Review and Ranitidine Label ), CLEMASTIN (View Clemastin Review and Clemastin Label ). Patient was hospitalized.

6977180-7 | Dizziness, Hypotension, Neutropenia
Patient was taking Lapatinib (View Usage). After Lapatinib was administered, patient had the following side effects: dizziness (What is dizziness?), hypotension, neutropenia on Sep 08, 2010 from SOUTH AFRICA Additional patient health information: Female patient , weighting 158.7 lb, was diagnosed with breast cancer metastatic, hypertension, prophylaxis, back pain (What is back pain?), hypothyroidism and. Lapatinib dosage: . During the same period patient was treated with DIOVAN HCT (View Diovan Hct Review and Diovan Hct Label ), ACETYLSALICYLIC ACID (View Acetylsalicylic Acid Review and Acetylsalicylic Acid Label ), ACETAMINOPHEN (View Acetaminophen Review and Acetaminophen Label ), LEVOTHYROXINE SODIUM (View Levothyroxine Sodium Review and Levothyroxine Sodium Label ), CAPECITABINE (1450 Mg Twice Daily Days 1-14 Of Cycle) (View Capecitabine Review and Capecitabine Label ). Patient was hospitalized.

6976871-1 | Alanine Aminotransferase, Aspartate Aminotransferase, Blood Alkaline Phosphatase, Chronic Fatigue Syndrome, Gamma-glutamyltransferase Increased
Adverse event was reported on Sep 03, 2010 by a Female patient taking Lapatinib (View Usage) (Dosage: ) was diagnosed with breast cancer (What is breast cancer?), myalgia, herpes zoster and. Location: GERMANY , weighting 178.6 lb, Patient experienced the following unwanted or unexpected effects: alanine aminotransferase, aspartate aminotransferase, blood alkaline phosphatase, chronic fatigue syndrome (What is chronic fatigue syndrome?), gamma-glutamyltransferase increased. During the same period patient was treated with DOCETAXEL (75mgm2 Every 3 Weeks) (View Docetaxel Review and Docetaxel Label ), DICLOFENAC (50mg As Required) (View Diclofenac Review and Diclofenac Label ), ZOSTEX (125mg Per Day) (View Zostex Review and Zostex Label ).

6976867-X | Hypokalaemia, Leukopenia, Pyrexia
on Aug 31, 2010 Male patient from NETHERLANDS , weighting 156.5 lb, was diagnosed with gastric cancer and was treated with Lapatinib (View Usage). Patient had the following side effects: hypokalaemia, leukopenia, pyrexia. Lapatinib dosage: 1250mg Per Day. During the same period patient was treated with OXALIPLATIN (240mg Every 3 Weeks) (View Oxaliplatin Review and Oxaliplatin Label ), CAPECITABINE (1650mg Twice Per Day) (View Capecitabine Review and Capecitabine Label ). Patient was hospitalized.

6970878-6 | Skin Graft
on Aug 30, 2010 Female patient from IRELAND , weighting 132.7 lb, was diagnosed with breast cancer (What is breast cancer?) and was treated with Lapatinib (View Usage). After Lapatinib was administered, patient had the following side effects: skin graft. Lapatinib dosage: 1500mg Per Day. During the same period patient was treated with TRASTUZUMAB (2mgk Weekly) (View Trastuzumab Review and Trastuzumab Label ), FEMARA (2.5mg Per Day) (View Femara Review and Femara Label ), VENTOLIN (View Ventolin Review and Ventolin Label ). Patient was hospitalized.

6970868-3 | Atrial Fibrillation, Dyspnoea, Oedema Peripheral
Patient was taking Lapatinib (View Usage). Patient experienced the following unwanted or unexpected effects: atrial fibrillation (What is atrial fibrillation?), dyspnoea, oedema peripheral on Sep 01, 2010 from GERMANY Additional patient health information: Female patient , weighting 154.3 lb, was diagnosed with breast cancer (What is breast cancer?), arrhythmia (What is arrhythmia?), hypertension and. Lapatinib dosage: 1000mg Per Day. During the same period patient was treated with DOCETAXEL (75mgm2 Every 3 Weeks) (View Docetaxel Review and Docetaxel Label ), TRASTUZUMAB (2mgk Weekly) (View Trastuzumab Review and Trastuzumab Label ), PROPAFENONE HCL (150mg Three Times Per Day) (View Propafenone Hcl Review and Propafenone Hcl Label ), RAMIPRIL (2.5mg Per Day) (View Ramipril Review and Ramipril Label ), ASPIRIN (100mg Per Day) (View Aspirin Review and Aspirin Label ). Patient was hospitalized.

6968135-7 | Atrial Fibrillation
Adverse event was reported on Aug 27, 2010 by a Female patient taking Lapatinib (View Usage) (Dosage: 1000mg Per Day) was diagnosed with breast cancer (What is breast cancer?), arrhythmia (What is arrhythmia?), hypertension and. Location: GERMANY , weighting 154.3 lb, Patient had the following side effects: atrial fibrillation (What is atrial fibrillation?). During the same period patient was treated with DOCETAXEL (75mgm2 Every 3 Weeks) (View Docetaxel Review and Docetaxel Label ), TRASTUZUMAB (2mgk Weekly) (View Trastuzumab Review and Trastuzumab Label ), PROPAFENONE HCL (150mg Three Times Per Day) (View Propafenone Hcl Review and Propafenone Hcl Label ), RAMIPRIL (2.5mg Per Day) (View Ramipril Review and Ramipril Label ), ASPIRIN (100mg Per Day) (View Aspirin Review and Aspirin Label ). Patient was hospitalized.

6968130-8 | Asthenia, Diarrhoea, Dizziness, Mucosal Inflammation
on Aug 31, 2010 Female patient from KOREA, REPUBLIC OF , weighting 106.9 lb, was diagnosed with breast cancer (What is breast cancer?) and was treated with Lapatinib (View Usage). After Lapatinib was administered, patient had the following side effects: asthenia, diarrhoea, dizziness (What is dizziness?), mucosal inflammation. Lapatinib dosage: 750mg Per Day. During the same period patient was treated with PACLITAXEL (80mgm2 Weekly) (View Paclitaxel Review and Paclitaxel Label ). Patient was hospitalized.

6968123-0 | Alanine Aminotransferase Increased, Blood Bilirubin Increased
on Aug 31, 2010 Female patient from CHINA , weighting 165.3 lb, was diagnosed with breast cancer (What is breast cancer?) and was treated with Lapatinib (View Usage). Patient experienced the following unwanted or unexpected effects: alanine aminotransferase increased, blood bilirubin increased. Lapatinib dosage: 1500mg Per Day. During the same period patient was treated with TRASTUZUMAB (2mgk Weekly) (View Trastuzumab Review and Trastuzumab Label ).

6965482-X | Chills, Device Related Infection, Injection Site Reaction, Pain
Patient was taking Lapatinib (View Usage). Patient had the following side effects: chills, device related infection, injection site reaction, pain (What is pain?) on Aug 26, 2010 from GERMANY Additional patient health information: Female patient , weighting 167.6 lb, . Lapatinib dosage: 1250mg Per Day. During the same period patient was treated with PACLITAXEL (143.2mg Weekly) (View Paclitaxel Review and Paclitaxel Label ), IBUPROFEN (View Ibuprofen Review and Ibuprofen Label ), LOPERAMIDE (View Loperamide Review and Loperamide Label ), RANITIDINE (View Ranitidine Review and Ranitidine Label ), CLEMASTIN (View Clemastin Review and Clemastin Label ). Patient was hospitalized.