LOMUSTINE Side Effects

6771361-3 | Abdominal Pain, Accidental Overdose, Bone Marrow Failure, Hepatotoxicity, Ileitis, Mental Status Changes, Multi-organ Failure, Neurotoxicity, Pancytopenia
on Jun 11, 2010 Female patient from UNITED STATES , 28 years of age, was diagnosed with anaplastic astrocytoma and was treated with Lomustine (View Usage). Patient experienced the following unwanted or unexpected effects: abdominal pain (What is abdominal pain?), accidental overdose, bone marrow failure, hepatotoxicity, ileitis, mental status changes, multi-organ failure, neurotoxicity, pancytopenia. Lomustine dosage: . Patient was hospitalized.

6723480-5 | Ecthyma, Febrile Neutropenia, Inappropriate Antidiuretic Hormone Secretion
Patient was taking Lomustine (View Usage). Patient had the following side effects: ecthyma, febrile neutropenia, inappropriate antidiuretic hormone secretion on May 03, 2010 from NETHERLANDS Additional patient health information: Male patient , 37 years of age, was diagnosed with astrocytoma and. Lomustine dosage: On Day 1. During the same period patient was treated with VINCRISTINE SULFATE (On Days 8 And 29) (View Vincristine Sulfate Review and Vincristine Sulfate Label ), PROCARBAZINE (Days 8-21) (View Procarbazine Review and Procarbazine Label ), DEXAMETHASONE (View Dexamethasone Review and Dexamethasone Label ), LEVETIRACETAM (View Levetiracetam Review and Levetiracetam Label ), VALPROATE SODIUM (View Valproate Sodium Review and Valproate Sodium Label ), CLOBAZAM (View Clobazam Review and Clobazam Label ). Patient was hospitalized.

6255948-2 | Acute Myeloid Leukaemia, Myelodysplastic Syndrome
Adverse event was reported on Jun 29, 2009 by a Male patient taking Lomustine (View Usage) (Dosage: ) was diagnosed with glioma and. Location: UNITED STATES , 59 years of age, After Lomustine was administered, patient had the following side effects: acute myeloid leukaemia, myelodysplastic syndrome. During the same period patient was treated with TEMOZOLOMIDE (Total Dose 18000 Mg/m2 (range 6000-28000 Mg/m2).) (View Temozolomide Review and Temozolomide Label ), VINCRISTINE (View Vincristine Review and Vincristine Label ).

5839754-6 | Blood Creatinine Increased, Meningitis Cryptococcal, Optic Atrophy, Pulmonary Embolism
on Aug 07, 2008 Male patient from UNITED STATES , 33 years of age, was treated with Lomustine (View Usage). Patient experienced the following unwanted or unexpected effects: blood creatinine increased, meningitis cryptococcal, optic atrophy, pulmonary embolism (What is pulmonary embolism?). Lomustine dosage: . During the same period patient was treated with AMPHOTERICIN B (View Amphotericin B Review and Amphotericin B Label ), DEXAMETHASONE (View Dexamethasone Review and Dexamethasone Label ), TEMOZOLOMIDE (View Temozolomide Review and Temozolomide Label ), FLUCYTOSINE (View Flucytosine Review and Flucytosine Label ).


5834892-6 | Blood Creatinine Increased, Meningitis Cryptococcal, Optic Atrophy, Pulmonary Embolism
on Aug 04, 2008 Male patient from UNITED STATES , 33 years of age, was treated with Lomustine (View Usage). Patient had the following side effects: blood creatinine increased, meningitis cryptococcal, optic atrophy, pulmonary embolism (What is pulmonary embolism?). Lomustine dosage: . During the same period patient was treated with AMPHOTERICIN B (View Amphotericin B Review and Amphotericin B Label ), DEXAMETHASONE (View Dexamethasone Review and Dexamethasone Label ), TEMOZOLOMIDE (View Temozolomide Review and Temozolomide Label ), FLUCYTOSINE (View Flucytosine Review and Flucytosine Label ).

5779032-7 | Deafness
Patient was taking Lomustine (View Usage). After Lomustine was administered, patient had the following side effects: deafness on Jun 18, 2008 from AUSTRALIA Additional patient health information: Male patient , child 12 years of age, . Lomustine dosage: Given 1 Time. Capsule. During the same period patient was treated with CISPLATIN (Injection) (View Cisplatin Review and Cisplatin Label ), PHENYTOIN SODIUM (Capsule) (View Phenytoin Sodium Review and Phenytoin Sodium Label ), LACTULOSE (View Lactulose Review and Lactulose Label ), COLOXYL + SENNA (Tablet 1 Dosage Form = 2(units Not Spscified)) (View Coloxyl + Senna Review and Coloxyl + Senna Label ), TRIMETHOPRIM + SULFAMETHOXAZOLE (1 Dosage Form = 2(units Not Specified).) (View Trimethoprim + Sulfamethoxazole Review and Trimethoprim + Sulfamethoxazole Label ).

5680183-6 | Febrile Neutropenia
Adverse event was reported on Mar 21, 2008 by a Female patient taking Lomustine (View Usage) (Dosage: ) was diagnosed with glioblastoma multiforme and. Location: UNITED STATES , 43 years of age, weighting 286.6 lb, Patient experienced the following unwanted or unexpected effects: febrile neutropenia. During the same period patient was treated with ACETAMINOPHEN (View Acetaminophen Review and Acetaminophen Label ), DEXAMETHASONE TAB (31jan08-ongoing) (View Dexamethasone Tab Review and Dexamethasone Tab Label ), FAMOTIDINE (View Famotidine Review and Famotidine Label ), PRINZIDE (View Prinzide Review and Prinzide Label ), LEVETIRACETAM (View Levetiracetam Review and Levetiracetam Label ), ONDANSETRON (30jan08-ongoing) (View Ondansetron Review and Ondansetron Label ), ZOLPIDEM TARTRATE (View Zolpidem Tartrate Review and Zolpidem Tartrate Label ), LORAZEPAM (View Lorazepam Review and Lorazepam Label ). Patient was hospitalized.

5523400-5 | Epilepsy
on Nov 15, 2007 Female patient from CZECH REPUBLIC , 39 years of age, weighting 119.0 lb, was treated with Lomustine (View Usage). Patient had the following side effects: epilepsy (What is epilepsy?). Lomustine dosage: Once. During the same period patient was treated with KEPPRA (View Keppra Review and Keppra Label ), TEGRETOL (1 And 1/2 Tablets Per Day) (View Tegretol Review and Tegretol Label ), POTASSIUM CHLORIDE (View Potassium Chloride Review and Potassium Chloride Label ), RANITIDINE HCL (View Ranitidine Hcl Review and Ranitidine Hcl Label ), CITALOPRAM (View Citalopram Review and Citalopram Label ), DEXAMETHASONE (View Dexamethasone Review and Dexamethasone Label ). Patient was hospitalized.

5402829-X | Abdominal Pain, Accidental Overdose, Bone Marrow Failure, Hepatotoxicity, Ileitis, Mental Status Changes, Multi-organ Failure, Neurotoxicity, Pancytopenia
on Jul 25, 2007 Female patient from UNITED STATES , 28 years of age, was diagnosed with anaplastic astrocytoma and was treated with Lomustine (View Usage). After Lomustine was administered, patient had the following side effects: abdominal pain (What is abdominal pain?), accidental overdose, bone marrow failure, hepatotoxicity, ileitis, mental status changes, multi-organ failure, neurotoxicity, pancytopenia. Lomustine dosage: . Patient was hospitalized.

5402642-3 | Abdominal Pain, Bone Marrow Failure, Mental Status Changes, Overdose, Pulmonary Toxicity
Patient was taking Lomustine (View Usage). Patient experienced the following unwanted or unexpected effects: abdominal pain (What is abdominal pain?), bone marrow failure, mental status changes, overdose, pulmonary toxicity on Jul 25, 2007 from UNITED STATES Additional patient health information: Female patient , 28 years of age, was diagnosed with anaplastic astrocytoma and. Lomustine dosage: .

5267636-X | Cough, Dyspnoea, Febrile Neutropenia, Hypoxia, Pneumonia
Adverse event was reported on Mar 15, 2007 by a Female patient taking Lomustine (View Usage) (Dosage: ) was diagnosed with glioblastoma multiforme, brain oedema, dyspepsia, vomiting and. Location: UNITED STATES , 65 years of age, weighting 134.5 lb, Patient had the following side effects: cough, dyspnoea, febrile neutropenia, hypoxia, pneumonia (What is pneumonia?). During the same period patient was treated with DEXAMETHASONE (View Dexamethasone Review and Dexamethasone Label ), RANITIDINE (View Ranitidine Review and Ranitidine Label ), PROCHLORPERAZINE (View Prochlorperazine Review and Prochlorperazine Label ), FUROSEMIDE (View Furosemide Review and Furosemide Label ). Patient was hospitalized.

5267599-7 | Abdominal Pain, Bone Marrow Failure, Mental Status Changes, Overdose, Pulmonary Toxicity
on Mar 14, 2007 Female patient from UNITED STATES , 28 years of age, was diagnosed with anaplastic astrocytoma and was treated with Lomustine (View Usage). After Lomustine was administered, patient had the following side effects: abdominal pain (What is abdominal pain?), bone marrow failure, mental status changes, overdose, pulmonary toxicity. Lomustine dosage: .

5264573-1 | Bone Marrow Failure, Convulsion, Overdose
on Mar 09, 2007 Male patient from TURKEY , 48 years of age, was diagnosed with glioblastoma multiforme and was treated with Lomustine (View Usage). Patient experienced the following unwanted or unexpected effects: bone marrow failure, convulsion, overdose. Lomustine dosage: . Patient was hospitalized.

5263700-X | Bone Marrow Failure, Mental Status Changes, Overdose, Pulmonary Toxicity
Patient was taking Lomustine (View Usage). Patient had the following side effects: bone marrow failure, mental status changes, overdose, pulmonary toxicity on Mar 08, 2007 from UNITED STATES Additional patient health information: Female patient , 28 years of age, was diagnosed with anaplastic astrocytoma and. Lomustine dosage: .

5263562-0 | Bone Marrow Failure, Mental Status Changes, Overdose, Pulmonary Toxicity
Adverse event was reported on Mar 08, 2007 by a Female patient taking Lomustine (View Usage) (Dosage: ) was diagnosed with anaplastic astrocytoma and. Location: UNITED STATES , 28 years of age, After Lomustine was administered, patient had the following side effects: bone marrow failure, mental status changes, overdose, pulmonary toxicity.

5263561-9 | Bone Marrow Failure, Gastrointestinal Necrosis, Nausea, Overdose, Postoperative Wound Infection, Pyrexia
on Mar 08, 2007 Female patient from UNITED STATES , 35 years of age, was diagnosed with anaplastic astrocytoma and was treated with Lomustine (View Usage). Patient experienced the following unwanted or unexpected effects: bone marrow failure, gastrointestinal necrosis, nausea (What is nausea?), overdose, postoperative wound infection, pyrexia. Lomustine dosage: . Patient was hospitalized.

5262651-4 | Febrile Neutropenia, Overdose, Thrombocytopenia
on Mar 09, 2007 Male patient from TURKEY , 38 years of age, was diagnosed with astrocytoma and was treated with Lomustine (View Usage). Patient had the following side effects: febrile neutropenia, overdose, thrombocytopenia. Lomustine dosage: . Patient was hospitalized.

5258540-1 | Abdominal Pain, Accidental Overdose, Bone Marrow Failure, Hepatotoxicity, Ileitis, Multi-organ Failure, Neurotoxicity, Pancytopenia, Pulmonary Toxicity
Patient was taking Lomustine (View Usage). After Lomustine was administered, patient had the following side effects: abdominal pain (What is abdominal pain?), accidental overdose, bone marrow failure, hepatotoxicity, ileitis, multi-organ failure, neurotoxicity, pancytopenia, pulmonary toxicity on Mar 05, 2007 from UNITED STATES Additional patient health information: Female patient , 28 years of age, . Lomustine dosage: . Patient was hospitalized.

5252887-0 | Cough, Dyspnoea, Febrile Neutropenia, Hypoxia, Pneumonia
Adverse event was reported on Feb 20, 2007 by a Female patient taking Lomustine (View Usage) (Dosage: ) was diagnosed with glioblastoma multiforme, brain oedema, dyspepsia, vomiting and. Location: UNITED STATES , 65 years of age, weighting 134.5 lb, Patient experienced the following unwanted or unexpected effects: cough, dyspnoea, febrile neutropenia, hypoxia, pneumonia (What is pneumonia?). During the same period patient was treated with DEXAMETHASONE (View Dexamethasone Review and Dexamethasone Label ), RANITIDINE (View Ranitidine Review and Ranitidine Label ), PROCHLORPERAZINE (View Prochlorperazine Review and Prochlorperazine Label ), FUROSEMIDE (View Furosemide Review and Furosemide Label ). Patient was hospitalized.

4596524-7 | Blood Creatinine Increased, Blood Lactate Dehydrogenase Increased, Tumour Lysis Syndrome
on Oct 28, 2003 Male patient from , 67 years of age, was treated with Lomustine (View Usage). Patient had the following side effects: blood creatinine increased, blood lactate dehydrogenase increased, tumour lysis syndrome. Lomustine dosage: . During the same period patient was treated with METHOTREXATE (View Methotrexate Review and Methotrexate Label ), CYCLOPHOSPHAMIDE (View Cyclophosphamide Review and Cyclophosphamide Label ).