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From simple mix-ups to fatal overdoses, medication mistakes happen, on average, once a day to every hospital patient, a new report says. Nationwide, at least 1.5 million people annually are harmed from drug errors, more than half of them in nursing homes.
Many Unfavorable Drug Studies Aren’t Published. Nearly a third of antidepressant drug studies are never published in the medical literature, and nearly all of those happen to show that the drug being tests failed to work.
Only Drugs That are Safe Should be put on the Market. Drug developers are just beginning to come to grips with recent FDA oversight reforms and how they will affect drug safety. But, it appears that industry and consumer advocates are not together on how well the overhaul will be able to prevent future drug safety scandals.

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Review Lotrel Safety Reports submitted to FDA

Total Lotrel reports: 237.
Lotrel FDA safety alerts: No.
Reported deaths: 6    Reported hospitalizations: 94.
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FDA Reported Lotrel Side Effects: angioedema, blood pressure inadequately controlled, dizziness, blood creatinine increased, oedema peripheral, swelling face, asthenia, swollen tongue, dysphagia, headache, nausea.
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Lotrel Side Effects Report #5399865-9
Consumer or non-health professional from UNITED STATES reported LOTREL problem on July 23, 2007. Female patient, 80 years of age, was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: hepatocellular damage. LOTREL dosage: unknown. During the same period patient was treated with NEXIUM, ETODOLAC. Patient recovered.

Lotrel Side Effects Report #5402332-7
LOTREL problem was reported by a Consumer or non-health professional from UNITED STATES on July 30, 2007. Female patient, 52 years of age, weighting 187.0 lb, was diagnosed with hypertension and was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: chest pain, disturbance in attention, eye swelling, fatigue, sinus disorder. LOTREL dosage: unknown. Patient recovered.

Lotrel Side Effects Report #5403621-2
Consumer or non-health professional from UNITED STATES reported LOTREL problem on July 23, 2007. Male patient, 49 years of age, weighting 238.0 lb, was diagnosed with hypertension and was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: arthralgia, blood pressure inadequately controlled, hypoaesthesia, oedema peripheral. LOTREL dosage: 5/20 MG, QD. Patient recovered.

Lotrel Side Effects Report #5405611-2
LOTREL problem was reported by a Consumer or non-health professional from UNITED STATES on July 27, 2007. Female patient, 39 years of age, weighting 193.0 lb, was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: glomerulonephritis, hypersensitivity, oedema peripheral. LOTREL dosage: unknown. During the same period patient was treated with LOPRESSOR, CATAFLAM, BACTRIM. Patient recovered.

Lotrel Side Effects Report #5405670-7
Physician from UNITED STATES reported LOTREL problem on July 24, 2007. Male patient, 84 years of age, weighting 165.4 lb, was diagnosed with hypertension, benign prostatic hyperplasia, urinary incontinence and was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: abdominal pain, anuria, asthenia, blood creatinine increased, chest pain, clostridium difficile colitis, contusion, dehydration, depression. LOTREL dosage: unknown. During the same period patient was treated with FLOMAX, DETROL, LIPITOR, CALCIUM CARBONATE W, ALLOPURINOL, DIFLUCAN, LISINOPRIL. Patient was hospitalized. Patient recovered.

Lotrel Side Effects Report #5406749-6
LOTREL problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 03, 2007. Female patient, 77 years of age, was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: asthenia, dyspnoea, feeling abnormal, gait disturbance, laboratory test abnormal, renal failure. LOTREL dosage: unknown. Patient was hospitalized. Patient recovered.

Lotrel Side Effects Report #5408065-5
Consumer or non-health professional from UNITED STATES reported LOTREL problem on July 30, 2007. Female patient was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: heart rate irregular. LOTREL dosage: unknown. Patient recovered.

Lotrel Side Effects Report #5408169-7
LOTREL problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 02, 2007. Male patient was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: blood glucose increased, blood pressure decreased. LOTREL dosage: 10/40 MG, UNK. Patient recovered.

Lotrel Side Effects Report #5409236-4
Consumer or non-health professional from UNITED STATES reported LOTREL problem on Aug 03, 2007. Male patient, 50 years of age, was diagnosed with cardiac disorder and was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: blood pressure inadequately controlled, myocardial infarction. LOTREL dosage: unknown. During the same period patient was treated with NORVASC, PLAVIX, ASPIRIN, METOPROLOL SUCCINATE. Patient recovered.

Lotrel Side Effects Report #5413211-3
LOTREL problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 06, 2007. Male patient, 35 years of age, was diagnosed with hypertension and was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: infertility male, sinusitis. LOTREL dosage: 5/20 MG, QD. During the same period patient was treated with SINGULAIR. Patient recovered.

Lotrel Side Effects Report #5414844-0
Consumer or non-health professional from UNITED STATES reported LOTREL problem on Aug 07, 2007. Female patient, 63 years of age, was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: dysphagia, sensation of foreign body. LOTREL dosage: 10/20 MG. During the same period patient was treated with FLONASE. Patient recovered.

Lotrel Side Effects Report #5416336-1
LOTREL problem was reported by a Physician from UNITED STATES on Aug 09, 2007. Female patient, 93 years of age, was diagnosed with hypertension and was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: colon cancer, joint stiffness, malaise, oedema peripheral, palpitations. LOTREL dosage: 5/20 MG, QD. Patient recovered.

Lotrel Side Effects Report #5416360-9
Consumer or non-health professional from UNITED STATES reported LOTREL problem on Aug 08, 2007. Female patient, 39 years of age, weighting 193.0 lb, was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: glomerulonephritis, hypersensitivity, oedema peripheral. LOTREL dosage: unknown. During the same period patient was treated with LOPRESSOR, CATAFLAM, BACTRIM. Patient recovered.

Lotrel Side Effects Report #5417726-3
LOTREL problem was reported by a Pharmacist from UNITED STATES on Aug 15, 2007. Female patient, weighting 130.0 lb, was diagnosed with hypertension and was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: dysphagia, stridor, swollen tongue. LOTREL dosage: unknown. During the same period patient was treated with ALLEGRA, SOTALOL HYDROCHLORIDE, XANAX, TIMOLOL MALEATE, MEGESTROL ACETATE, PAROXETINE. Patient was hospitalized. Patient recovered.

Lotrel Side Effects Report #5417784-6
Physician from UNITED STATES reported LOTREL problem on Aug 06, 2007. Male patient, 76 years of age, weighting 187.0 lb, was diagnosed with hypertension, type 2 diabetes mellitus, hyperlipidaemia and was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: angiopathy, angioplasty, blood creatinine increased, blood potassium decreased, clavicle fracture, dehydration, diabetes mellitus inadequate control, fall, hyperglycaemia. LOTREL dosage: unknown. During the same period patient was treated with METFORMIN, SIMVASTATIN, ASPIRIN, INSULIN, GLUCOPHAGE, ZOCOR, FLOMAX. Patient was hospitalized. Patient recovered.

Lotrel Side Effects Report #5423308-X
LOTREL problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 15, 2007. Female patient, 58 years of age, weighting 180.0 lb, was diagnosed with hypertension and was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: arrhythmia. LOTREL dosage: 10/20 MG, QD. During the same period patient was treated with TOPROL, ZOCOR, PRILOSEC, IMITREX. Patient was hospitalized. Patient recovered.

Lotrel Side Effects Report #5424647-9
Physician from UNITED STATES reported LOTREL problem on Aug 15, 2007. Female patient, 78 years of age, weighting 160.1 lb, was diagnosed with hypertension, coronary artery disease, dyslipidaemia and was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: asthenia, confusional state, decreased appetite, hypertension, hyponatraemia. LOTREL dosage: unknown. During the same period patient was treated with TOPROL, VYTORIN, ASPIRIN. Patient was hospitalized. Patient recovered.

Lotrel Side Effects Report #5427165-7
LOTREL problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 20, 2007. Male patient, 82 years of age, was diagnosed with hypertension, diabetes mellitus and was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: aphasia, cerebrovascular accident, dizziness, dysphasia, hypoaesthesia, muscular weakness, nausea, pulmonary mass, syncope. LOTREL dosage: 5/10 MG, QD. During the same period patient was treated with GLUCOVANCE, FLOMAX. Patient was hospitalized. Patient recovered.

Lotrel Side Effects Report #5427682-X
Consumer or non-health professional from UNITED STATES reported LOTREL problem on Aug 20, 2007. Male patient, 82 years of age, was diagnosed with hypertension, diabetes mellitus and was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: aphasia, cerebrovascular accident, dizziness, dysphasia, hypoaesthesia, muscular weakness, nausea, pulmonary mass, syncope. LOTREL dosage: 5/10 MG, QD. During the same period patient was treated with GLUCOVANCE, FLOMAX. Patient was hospitalized. Patient recovered.

Lotrel Side Effects Report #5429079-5
LOTREL problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 17, 2007. Female patient, 70 years of age, was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: blood cholesterol increased, blood pressure inadequately controlled, depression, hypertension. LOTREL dosage: unknown. During the same period patient was treated with ATENOLOL. Patient recovered.

Lotrel Side Effects Report #5429383-0
Physician from UNITED STATES reported LOTREL problem on Aug 21, 2007. Female patient, 50 years of age, was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: inflammation, pain, pancreatitis. LOTREL dosage: unknown. During the same period patient was treated with CLONIDINE, MINOXIDIL, TEKTURNA. Patient was hospitalized. Patient recovered.

Lotrel Side Effects Report #5429725-6
LOTREL problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 17, 2007. Female patient, 70 years of age, was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: blood cholesterol increased, blood pressure inadequately controlled, depression. LOTREL dosage: unknown. During the same period patient was treated with ATENOLOL. Patient recovered.

Lotrel Side Effects Report #5440769-0
Physician from UNITED STATES reported LOTREL problem on Aug 21, 2007. Male patient, 84 years of age, weighting 165.4 lb, was diagnosed with hypertension, benign prostatic hyperplasia, urinary incontinence and was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: abdominal pain, anuria, asthenia, blood creatinine increased, chest pain, colitis, confusional state, contusion, dehydration. LOTREL dosage: unknown. During the same period patient was treated with FLOMAX, DETROL, LIPITOR, CALCIUM CARBONATE W, ALLOPURINOL, DIFLUCAN, LISINOPRIL. Patient was hospitalized. Patient recovered.

Lotrel Side Effects Report #5440781-1
LOTREL problem was reported by a Physician from UNITED STATES on Aug 21, 2007. Male patient, 84 years of age, weighting 165.4 lb, was diagnosed with hypertension, benign prostatic hyperplasia, urinary incontinence and was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: abdominal pain, anuria, asthenia, blood creatinine increased, chest pain, colitis, confusional state, contusion, dehydration. LOTREL dosage: unknown. During the same period patient was treated with FLOMAX, DETROL, LIPITOR, CALCIUM CARBONATE W, ALLOPURINOL, DIFLUCAN, LISINOPRIL. Patient was hospitalized. Patient recovered.

Lotrel Side Effects Report #5441374-2
Physician from UNITED STATES reported LOTREL problem on Aug 24, 2007. Female patient, 84 years of age, weighting 140.0 lb, was diagnosed with hypertension and was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: weight decreased. LOTREL dosage: 10/20 MG, QD. During the same period patient was treated with PLAVIX. Patient recovered.

Lotrel Side Effects Report #5442558-X
LOTREL problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 27, 2007. Female patient, 70 years of age, was diagnosed with hypertension, chronic obstructive pulmonary disease and was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: blood creatinine increased, blood potassium increased, body temperature increased, confusional state, delirium, herpes zoster, hypoalbuminaemia, hyponatraemia. LOTREL dosage: unknown. During the same period patient was treated with FOSAMAX, ADVAIR DISKUS, XOPENEX, SPIRIVA, SINGULAIR, OXYGEN. Patient was hospitalized. Patient recovered.

Lotrel Side Effects Report #5442985-0
Consumer or non-health professional from UNITED STATES reported LOTREL problem on Aug 25, 2007. Female patient, 51 years of age, was diagnosed with hypertension and was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: dizziness, eating disorder, headache, hypotension, loss of consciousness, nausea, vomiting. LOTREL dosage: 10/20 MG, QD. During the same period patient was treated with BENICAR. Patient recovered.

Lotrel Side Effects Report #5444264-4
LOTREL problem was reported by a Consumer or non-health professional from UNITED STATES on Sept 04, 2007. Female patient, weighting 160.0 lb, was diagnosed with blood pressure decreased and was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased. LOTREL dosage: unknown. During the same period patient was treated with HYDROCHLOROTHIAZIDE. Patient recovered.

Lotrel Side Effects Report #5448232-8
Physician from UNITED STATES reported LOTREL problem on Aug 31, 2007. Male patient, 64 years of age, weighting 209.4 lb, was diagnosed with hypertension and was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: dehydration, hypokalaemia, palpitations, vomiting. LOTREL dosage: unknown. During the same period patient was treated with HYDROCHLOROTHIAZIDE. Patient was hospitalized. Patient recovered.

Lotrel Side Effects Report #5452169-8
LOTREL problem was reported by a Physician from UNITED STATES on Sept 05, 2007. Male patient, 76 years of age, weighting 187.0 lb, was diagnosed with hypertension, type 2 diabetes mellitus, hyperlipidaemia and was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: angiopathy, angioplasty, blood creatinine increased, blood potassium decreased, clavicle fracture, dehydration, diabetes mellitus inadequate control, fall, hyperglycaemia. LOTREL dosage: unknown. During the same period patient was treated with METFORMIN, SIMVASTATIN, ASPIRIN, INSULIN, GLUCOPHAGE, ZOCOR, FLOMAX. Patient was hospitalized. Patient recovered.

Lotrel Side Effects Report #5455041-2
Consumer or non-health professional from UNITED STATES reported LOTREL problem on Sept 11, 2007. Female patient was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: blood pressure inadequately controlled, cataract, headache. LOTREL dosage: 5/20 MG, UNK. During the same period patient was treated with BENICAR HCT, LORAZEPAM. Patient recovered.

Lotrel Side Effects Report #5456895-6
LOTREL problem was reported by a Physician from UNITED STATES on Sept 17, 2007. Female patient, weighting 179.0 lb, was diagnosed with hypertension and was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: angioedema, chest discomfort. LOTREL dosage: unknown. During the same period patient was treated with FOSAMAX, EFFEXOR. Patient recovered.

Lotrel Side Effects Report #5463974-6
Physician from UNITED STATES reported LOTREL problem on Sept 13, 2007. Male patient, 64 years of age, weighting 209.4 lb, was diagnosed with hypertension and was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: hypokalaemia, palpitations, vomiting. LOTREL dosage: unknown. During the same period patient was treated with HYDROCHLOROTHIAZIDE. Patient was hospitalized. Patient recovered.

Lotrel Side Effects Report #5465267-X
LOTREL problem was reported by a Physician from UNITED STATES on Aug 31, 2007. Female patient, 89 years of age, weighting 108.0 lb, was diagnosed with hypertension and was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, cerebrovascular accident, coronary artery disease, fall, head injury, hypertensive heart disease, loss of consciousness. LOTREL dosage: unknown. During the same period patient was treated with LASIX, GUANFACINE HYDROCHLORIDE. Patient was hospitalized. Patient died on 11/17/2006.

Lotrel Side Effects Report #5469325-5
Consumer or non-health professional from UNITED STATES reported LOTREL problem on Sept 17, 2007. Female patient, 64 years of age, was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: angioedema, diarrhoea, dysstasia, haematochezia, hypotension, intestinal congestion, lymphocyte count decreased. LOTREL dosage: unknown. Patient was hospitalized. Patient recovered.

Lotrel Side Effects Report #5469631-4
LOTREL problem was reported by a Consumer or non-health professional from UNITED STATES on Sept 17, 2007. Female patient, 64 years of age, was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: angioedema, diarrhoea, dysstasia, haematochezia, hypotension, intestinal congestion, lymphocyte count decreased. LOTREL dosage: unknown. Patient was hospitalized. Patient recovered.

Lotrel Side Effects Report #5470594-6
Consumer or non-health professional from UNITED STATES reported LOTREL problem on Sept 20, 2007. Female patient was treated with LOTREL. After drug was administered, patient experienced the following problems/side effects: angioedema, dyspnoea, urticaria. LOTREL dosage: 10/20 MG, UNK. Patient was hospitalized. Patient recovered.

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hepatocellular damage chest pain, disturbance in attention, eye swelling, fatigue, sinus disorder arthralgia, blood pressure inadequately controlled, hypoaesthesia, oedema peripheral, was diagnosed with hypertension and was diagnosed with hypertension and was diagnosed with hypertension, benign prostatic hyperplasia, urinary incontinence and