MACUGEN Side Effects

7009344-0 | Vitreous Haemorrhage
on Sep 03, 2010 Male patient from JAPAN , 88 years of age, weighting 145.3 lb, was treated with Macugen (View Usage). Patient experienced the following unwanted or unexpected effects: vitreous haemorrhage. Macugen dosage: 0.3mg, Intraocular. During the same period patient was treated with CANDESARTAN CILEXETIL (View Candesartan Cilexetil Review and Candesartan Cilexetil Label ), ASPIRIN (View Aspirin Review and Aspirin Label ), ALLOPURINOL (View Allopurinol Review and Allopurinol Label ), CARVEDILOL (View Carvedilol Review and Carvedilol Label ), AMLODIN (AMLODIPINE BESTLATE) TABLET (View Amlodin (amlodipine Bestlate) Tablet Review and Amlodin (amlodipine Bestlate) Tablet Label ). Patient was hospitalized.

6917506-3 | Blood Pressure Decreased, Cardiac Failure, Condition Aggravated, Urinary Tract Infection, Ventricular Hypokinesia
Patient was taking Macugen (View Usage). Patient had the following side effects: blood pressure decreased, cardiac failure, condition aggravated, urinary tract infection (What is urinary tract infection?), ventricular hypokinesia on Jul 22, 2010 from JAPAN Additional patient health information: Female patient , 76 years of age, weighting 106.9 lb, . Macugen dosage: 0.3mg, Intraocular. During the same period patient was treated with LEVOFLOXACIN (View Levofloxacin Review and Levofloxacin Label ), MROMFENAC SODIUM (BROMFENAC SODIUM) (View Mromfenac Sodium (bromfenac Sodium) Review and Mromfenac Sodium (bromfenac Sodium) Label ), KENACORT A OPHTHALMIC OINTMENT (View Kenacort-a Ophthalmic Ointment Review and Kenacort-a Ophthalmic Ointment Label ). Patient was hospitalized.

6894767-0 | Cerebrovascular Accident, Condition Aggravated, Quality Of Life Decreased, Retinal Neovascularisation, Visual Acuity Reduced
Adverse event was reported on Jul 13, 2010 by a Male patient taking Macugen (View Usage) (Dosage: 0 .3mg, Cyclic, Intraocular) . Location: SPAIN , 85 years of age, After Macugen was administered, patient had the following side effects: cerebrovascular accident, condition aggravated, quality of life decreased, retinal neovascularisation, visual acuity reduced.

6839242-4 |
on May 23, 2010 Male patient from CZECH REPUBLIC , 81 years of age, weighting 198.4 lb, was treated with Macugen (View Usage). . Macugen dosage: 0.3 Mg, Every 6 Weeks, Intraocular. During the same period patient was treated with LUSOPRESS (NITRENDIPINE) (View Lusopress (nitrendipine) Review and Lusopress (nitrendipine) Label ), TENOLOC (CELIPROLOL HYDROCHLORIDE) (View Tenoloc (celiprolol Hydrochloride) Review and Tenoloc (celiprolol Hydrochloride) Label ), AMILORIDE HCL W/HYDROCHLOROTHIAZIDE (AMILORIDE, HYDROCHLOROTHIAZIDE) (View Amiloride Hcl W/hydrochlorothiazide (amiloride, Hydrochlorothiazide) Review and Amiloride Hcl W/hydrochlorothiazide (amiloride, Hydrochlorothiazide) Label ), WARFARIN SODIUM (View Warfarin Sodium Review and Warfarin Sodium Label ).


6814673-7 |
on Jun 21, 2010 Male patient from CZECH REPUBLIC , 81 years of age, weighting 198.4 lb, was treated with Macugen (View Usage). . Macugen dosage: 0.3 Mg, Every 6 Weeks, Intraocular. During the same period patient was treated with LUSOPRESS (NITRENDIPINE) (View Lusopress (nitrendipine) Review and Lusopress (nitrendipine) Label ), TENOLOC (ELIPROLOL HYDROCHLORIDE) (View Tenoloc (eliprolol Hydrochloride) Review and Tenoloc (eliprolol Hydrochloride) Label ), AMILORIDE HCL W/HYDROCHLOROTHIAZIDE (AMILORIDE HYDROCHLORIDE, HYDROCHL (View Amiloride Hcl W/hydrochlorothiazide (amiloride Hydrochloride, Hydrochl Review and Amiloride Hcl W/hydrochlorothiazide (amiloride Hydrochloride, Hydrochl Label ), WARFARIN SODIUM (View Warfarin Sodium Review and Warfarin Sodium Label ).

6809875-X | Optic Ischaemic Neuropathy, Visual Acuity Reduced
Patient was taking Macugen (View Usage). After Macugen was administered, patient had the following side effects: optic ischaemic neuropathy, visual acuity reduced on Jun 09, 2010 from JAPAN Additional patient health information: Female patient , 72 years of age, weighting 133.2 lb, . Macugen dosage: 0.3mg In The Right Eye, Intraocular. During the same period patient was treated with MOXIFLOXACIN HYDROCHLORIDE (MOXIELOXACIN HYDROCHLORIDE) (View Moxifloxacin Hydrochloride (moxieloxacin Hydrochloride) Review and Moxifloxacin Hydrochloride (moxieloxacin Hydrochloride) Label ), LEVOFLOXACIN (View Levofloxacin Review and Levofloxacin Label ), RINDERON A (BETAMFTHASONE SODIUM PHOSPHATE, NEOMYCIN SULFATE) (View Rinderon A (betamfthasone Sodium Phosphate, Neomycin Sulfate) Review and Rinderon A (betamfthasone Sodium Phosphate, Neomycin Sulfate) Label ), BROMFENAC SODIUM (BROMFENAC SODIUM) (View Bromfenac Sodium (bromfenac Sodium) Review and Bromfenac Sodium (bromfenac Sodium) Label ), FLOMOX (CEFCAPENE PIVOXIL HYDROCHLORIDE) (View Flomox (cefcapene Pivoxil Hydrochloride) Review and Flomox (cefcapene Pivoxil Hydrochloride) Label ), SELBEX (TEPRENONE) (View Selbex (teprenone) Review and Selbex (teprenone) Label ).

6776494-3 | Rash
Adverse event was reported on May 28, 2010 by a Male patient taking Macugen (View Usage) (Dosage: ) was diagnosed with macular oedema and. Location: GERMANY , 82 years of age, Patient experienced the following unwanted or unexpected effects: rash (What is rash?).

6750991-9 | Optic Ischaemic Neuropathy
on May 12, 2010 Female patient from JAPAN , weighting 133.2 lb, was diagnosed with choroidal neovascularisation and was treated with Macugen (View Usage). Patient had the following side effects: optic ischaemic neuropathy. Macugen dosage: 0.3mg In The Right Eye, Intraocular. During the same period patient was treated with MOXIFLOXACIN HCL (View Moxifloxacin Hcl Review and Moxifloxacin Hcl Label ), LEVOFLOXACIN (View Levofloxacin Review and Levofloxacin Label ), RINDERON A (BETAMETHASONE SODIUM PHOSPHATE, NEOMYCIN SULFATE) (View Rinderon A (betamethasone Sodium Phosphate, Neomycin Sulfate) Review and Rinderon A (betamethasone Sodium Phosphate, Neomycin Sulfate) Label ), BROMFENAC SODIUM (BROMFENAC SODIUM) (View Bromfenac Sodium (bromfenac Sodium) Review and Bromfenac Sodium (bromfenac Sodium) Label ), FLOMOX (CEFCAPENE PIVOXIL HYDROCHLORIDE) (View Flomox (cefcapene Pivoxil Hydrochloride) Review and Flomox (cefcapene Pivoxil Hydrochloride) Label ), SELBEX (TEPRENONE) (View Selbex (teprenone) Review and Selbex (teprenone) Label ).

6683538-6 | Optic Ischaemic Neuropathy
on Apr 09, 2010 Female patient from JAPAN , 71 years of age, was treated with Macugen (View Usage). After Macugen was administered, patient had the following side effects: optic ischaemic neuropathy. Macugen dosage: Intraocular.

6674196-5 | Iiird Nerve Paralysis
Patient was taking Macugen (View Usage). Patient experienced the following unwanted or unexpected effects: iiird nerve paralysis on Mar 23, 2010 from UNITED STATES Additional patient health information: Female patient , 82 years of age, . Macugen dosage: 0.3mg, Unk, Intraocular. During the same period patient was treated with PREDNISONE (View Prednisone Review and Prednisone Label ), CYCLOPHOSPHAMIDE (View Cyclophosphamide Review and Cyclophosphamide Label ), ISOPTIN (View Isoptin Review and Isoptin Label ), PLAVIX (View Plavix Review and Plavix Label ), LANSOPRAZOLE (View Lansoprazole Review and Lansoprazole Label ). Patient was hospitalized.

6669819-0 | Cerebral Infarction
Adverse event was reported on Mar 17, 2010 by a Male patient taking Macugen (View Usage) (Dosage: ) was diagnosed with choroidal neovascularisation and. Location: JAPAN , 79 years of age, Patient had the following side effects: cerebral infarction. During the same period patient was treated with HYALEIN (HYALURONATE SODIUM) (View Hyalein (hyaluronate Sodium) Review and Hyalein (hyaluronate Sodium) Label ), FLOMOX (CEFCAPENE PIVOXIL HYDROCHLORIDE) (View Flomox (cefcapene Pivoxil Hydrochloride) Review and Flomox (cefcapene Pivoxil Hydrochloride) Label ), LEVOFLOXACIN (View Levofloxacin Review and Levofloxacin Label ). Patient was hospitalized.

6659727-3 | Endophthalmitis, Intraocular Pressure Increased, Visual Acuity Reduced
on Mar 10, 2010 Female patient from GERMANY , 81 years of age, was treated with Macugen (View Usage). After Macugen was administered, patient had the following side effects: endophthalmitis, intraocular pressure increased, visual acuity reduced. Macugen dosage: Intraocular. During the same period patient was treated with ISOPTO MAX (DEXAMETHASONE, NEOMYCIN SULFATE, POLYMYXIN B SULFATE) (View Isopto-max (dexamethasone, Neomycin Sulfate, Polymyxin B Sulfate) Review and Isopto-max (dexamethasone, Neomycin Sulfate, Polymyxin B Sulfate) Label ), XYLOCAIN GEL (LIDOCAINE HYDROCHLORIDE) (View Xylocain Gel (lidocaine Hydrochloride) Review and Xylocain Gel (lidocaine Hydrochloride) Label ), POVIDONE IODINE (View Povidone Iodine Review and Povidone Iodine Label ). Patient was hospitalized.

6651029-4 | Ischaemia, Ocular Hypertension
on Mar 08, 2010 Male patient from JAPAN , 89 years of age, weighting 116.2 lb, was treated with Macugen (View Usage). Patient experienced the following unwanted or unexpected effects: ischaemia, ocular hypertension. Macugen dosage: . During the same period patient was treated with AMLODIPINE (View Amlodipine Review and Amlodipine Label ), MICARDIS (View Micardis Review and Micardis Label ), LASIX (View Lasix Review and Lasix Label ), LIPITOR (View Lipitor Review and Lipitor Label ), CHLORMADINONE ACETATE TAB (View Chlormadinone Acetate Tab Review and Chlormadinone Acetate Tab Label ), TAMSULOSIN HYDROCHLORIDE (View Tamsulosin Hydrochloride Review and Tamsulosin Hydrochloride Label ), MITIGLINIDE (MITIGLINIDE) (View Mitiglinide (mitiglinide) Review and Mitiglinide (mitiglinide) Label ), VOGLIBOSE (VOGLIBOSE) (View Voglibose (voglibose) Review and Voglibose (voglibose) Label ).

6637455-8 | Blood Pressure Decreased, Cardiac Failure, Myocardial Infarction
Patient was taking Macugen (View Usage). Patient had the following side effects: blood pressure decreased, cardiac failure, myocardial infarction on Feb 26, 2010 from JAPAN Additional patient health information: Female patient , 76 years of age, weighting 106.9 lb, . Macugen dosage: 0.3mg, Intraocular. During the same period patient was treated with LEVOFLOXACIN (View Levofloxacin Review and Levofloxacin Label ), BROMFENAC SODIUM (BROMFENAC SODIUM) (View Bromfenac Sodium (bromfenac Sodium) Review and Bromfenac Sodium (bromfenac Sodium) Label ), KENACORT A OPHTHALMIC OINTMENT (View Kenacort-a Ophthalmic Ointment Review and Kenacort-a Ophthalmic Ointment Label ). Patient was hospitalized.

6619311-4 | Cerebrovascular Accident
Adverse event was reported on Feb 18, 2010 by a Female patient taking Macugen (View Usage) (Dosage: ) . Location: GERMANY , 83 years of age, After Macugen was administered, patient had the following side effects: cerebrovascular accident. During the same period patient was treated with PLAVIX (View Plavix Review and Plavix Label ), DYNACIL (FOSINOPRIL SODIUM) (View Dynacil (fosinopril Sodium) Review and Dynacil (fosinopril Sodium) Label ), METOPROLOL SUCCINATE (View Metoprolol Succinate Review and Metoprolol Succinate Label ), HYDROCHLOROTHIAZIDE (View Hydrochlorothiazide Review and Hydrochlorothiazide Label ), DIGITOXIN INJ (View Digitoxin Inj Review and Digitoxin Inj Label ), PENTAERYTHIRITOL TETRANITRATE TAB (View Pentaerythiritol Tetranitrate Tab Review and Pentaerythiritol Tetranitrate Tab Label ), FUROSEMIDE (View Furosemide Review and Furosemide Label ). Patient was hospitalized.

6609371-9 | Blood Pressure Decreased, Cardiac Failure, Coronary Artery Occlusion, Dyspnoea, Myocardial Infarction, Reflux Oesophagitis, Urinary Tract Infection, Ventricular Hypokinesia
on Jan 29, 2010 Female patient from JAPAN , 76 years of age, weighting 235.7 lb, was treated with Macugen (View Usage). Patient experienced the following unwanted or unexpected effects: blood pressure decreased, cardiac failure, coronary artery occlusion, dyspnoea, myocardial infarction, reflux oesophagitis, urinary tract infection (What is urinary tract infection?), ventricular hypokinesia. Macugen dosage: 0.3mg, Unk, Intravenous. During the same period patient was treated with LEVOFLOXACIN (View Levofloxacin Review and Levofloxacin Label ), BROMFENAC SODIUM (BROMFENAC SODIUM) (View Bromfenac Sodium (bromfenac Sodium) Review and Bromfenac Sodium (bromfenac Sodium) Label ). Patient was hospitalized.

6600336-X | Endophthalmitis
on Feb 01, 2010 Male patient from JAPAN , 83 years of age, was diagnosed with maculopathy and was treated with Macugen (View Usage). Patient had the following side effects: endophthalmitis. Macugen dosage: . During the same period patient was treated with AVASTIN (View Avastin Review and Avastin Label ), BENOXIL (OXYBUPROCAINE) (View Benoxil (oxybuprocaine) Review and Benoxil (oxybuprocaine) Label ), GATIFLOXACIN (View Gatifloxacin Review and Gatifloxacin Label ), LEVOFLOXACIN (View Levofloxacin Review and Levofloxacin Label ). Patient was hospitalized.

6589613-9 | Endophthalmitis
Patient was taking Macugen (View Usage). After Macugen was administered, patient had the following side effects: endophthalmitis on Jan 21, 2010 from UNITED STATES Additional patient health information: Female patient , 87 years of age, . Macugen dosage: Intraocular. During the same period patient was treated with PROGESTERONE (View Progesterone Review and Progesterone Label ), TRAZODONE HCL (View Trazodone Hcl Review and Trazodone Hcl Label ), ADDERALL 30 (View Adderall 30 Review and Adderall 30 Label ), LIPITOR (View Lipitor Review and Lipitor Label ), LEXAPRO (View Lexapro Review and Lexapro Label ), METOPROLOL TARTRATE (View Metoprolol Tartrate Review and Metoprolol Tartrate Label ), PLAVIX (View Plavix Review and Plavix Label ), AVAPRO (View Avapro Review and Avapro Label ).

6589314-7 | Elderly
Adverse event was reported on Jan 22, 2010 by a Male patient taking Macugen (View Usage) (Dosage: 0.3 Mg, Intraocular) was diagnosed with choroidal neovascularisation and. Location: JAPAN , 84 years of age, Patient experienced the following unwanted or unexpected effects: elderly. During the same period patient was treated with MYDRIN P (PHENYLEPHRINE HYDROCHLORIDE, TROPICAMIDE) (View Mydrin P (phenylephrine Hydrochloride, Tropicamide) Review and Mydrin P (phenylephrine Hydrochloride, Tropicamide) Label ), MOXIFLOXACIN HCL (View Moxifloxacin Hcl Review and Moxifloxacin Hcl Label ), XYLOCAINE (View Xylocaine Review and Xylocaine Label ), ISODINE (POVIDONE IODINE) (View Isodine (povidone-iodine) Review and Isodine (povidone-iodine) Label ).

6589313-5 |
on Jan 25, 2010 Male patient from JAPAN , 87 years of age, was treated with Macugen (View Usage). . Macugen dosage: 0.3mg, Intraocular.

6582625-0 | Endophthalmitis
on Jan 21, 2010 Female patient from UNITED STATES , 87 years of age, was treated with Macugen (View Usage). After Macugen was administered, patient had the following side effects: endophthalmitis. Macugen dosage: Intraocular.

6536947-X | Injection Site Haemorrhage, Vitreous Haemorrhage
Patient was taking Macugen (View Usage). Patient experienced the following unwanted or unexpected effects: injection site haemorrhage, vitreous haemorrhage on Dec 22, 2009 from Additional patient health information: Male patient , 80 years of age, . Macugen dosage: 0.3mg (intraocular). Patient was hospitalized.

6536931-6 | Myocardial Infarction
Adverse event was reported on Dec 24, 2009 by a Female patient taking Macugen (View Usage) (Dosage: 0.3 Mg, Intraocular) . Location: JAPAN , 76 years of age, Patient had the following side effects: myocardial infarction. During the same period patient was treated with LEVOFLOXACIN (View Levofloxacin Review and Levofloxacin Label ), BROMFENAC SODIUM (BROMFENAC SODIUM) (View Bromfenac Sodium (bromfenac Sodium) Review and Bromfenac Sodium (bromfenac Sodium) Label ), KENACORT A OPHTHALMIC OINTMENT (View Kenacort-a Ophthalmic Ointment Review and Kenacort-a Ophthalmic Ointment Label ). Patient was hospitalized.

6529649-7 | Angina Pectoris, Angle Closure Glaucoma, Cataract, Coronary Artery Disease, Diabetic Nephropathy, Gastritis, Periarthritis
on Dec 16, 2009 Female patient from INDIA , 55 years of age, weighting 172.0 lb, was diagnosed with diabetic retinal oedema and was treated with Macugen (View Usage). After Macugen was administered, patient had the following side effects: angina pectoris, angle closure glaucoma, cataract (What is cataract?), coronary artery disease (What is coronary artery disease?), diabetic nephropathy, gastritis, periarthritis. Macugen dosage: . During the same period patient was treated with INSULIN (View Insulin Review and Insulin Label ), METFORMIN HCL (View Metformin Hcl Review and Metformin Hcl Label ), MULTIVITAMINS (ASCORBIC ACID, ERGOCALCIFEROL, FOLIC ACID, NICOTINAMIDE (View Multivitamins (ascorbic Acid, Ergocalciferol, Folic Acid, Nicotinamide Review and Multivitamins (ascorbic Acid, Ergocalciferol, Folic Acid, Nicotinamide Label ), ENALAPRIL MALEATE (View Enalapril Maleate Review and Enalapril Maleate Label ), CALCIUM CARBONATE (View Calcium Carbonate Review and Calcium Carbonate Label ), TROPICAMIDE (View Tropicamide Review and Tropicamide Label ), PROPARACAINE HCL (View Proparacaine Hcl Review and Proparacaine Hcl Label ), OFLOXACIN (View Ofloxacin Review and Ofloxacin Label ).

6529181-0 | Ocular Hypertension
on Dec 15, 2009 Male patient from JAPAN , 89 years of age, weighting 116.2 lb, was treated with Macugen (View Usage). Patient experienced the following unwanted or unexpected effects: ocular hypertension. Macugen dosage: . During the same period patient was treated with AMLODIPINE (View Amlodipine Review and Amlodipine Label ), MICARDIS (View Micardis Review and Micardis Label ), LASIX (View Lasix Review and Lasix Label ), LIPITOR (View Lipitor Review and Lipitor Label ), CHLORMADINONE ACETATE TAB (View Chlormadinone Acetate Tab Review and Chlormadinone Acetate Tab Label ), TAMSULOSIN HCL (View Tamsulosin Hcl Review and Tamsulosin Hcl Label ), MITIGLINIDE (MITIGLINIDE) (View Mitiglinide (mitiglinide) Review and Mitiglinide (mitiglinide) Label ), VOGLIBOSE (VOGLIBOSE) (View Voglibose (voglibose) Review and Voglibose (voglibose) Label ).

6522698-4 | Myocardial Infarction
Patient was taking Macugen (View Usage). Patient had the following side effects: myocardial infarction on Dec 10, 2009 from JAPAN Additional patient health information: Female patient , 76 years of age, . Macugen dosage: 0.3 Mg, Intraocular. During the same period patient was treated with LEVOFLOXACIN (View Levofloxacin Review and Levofloxacin Label ), BROMFENAC SODIUM (BROMFENAC SODIUM) (View Bromfenac Sodium (bromfenac Sodium) Review and Bromfenac Sodium (bromfenac Sodium) Label ). Patient was hospitalized.

6502102-2 | Loss Of Consciousness, Malaise
Adverse event was reported on Nov 26, 2009 by a Female patient taking Macugen (View Usage) (Dosage: 0.3mg, Intraocular) was diagnosed with choroidal neovascularisation and. Location: JAPAN , 65 years of age, After Macugen was administered, patient had the following side effects: loss of consciousness, malaise. During the same period patient was treated with HYALEIN (HYALURONATE SODIUM) (View Hyalein (hyaluronate Sodium) Review and Hyalein (hyaluronate Sodium) Label ), TARIVID OPHTHALMIC (OFLOXACIN) (View Tarivid Ophthalmic (ofloxacin) Review and Tarivid Ophthalmic (ofloxacin) Label ), ARTIFICIAL TEARS (View Artificial Tears Review and Artificial Tears Label ). Patient was hospitalized.

6497730-7 | Eye Haemorrhage
on Nov 25, 2009 Male patient from GERMANY , 81 years of age, weighting 198.4 lb, was treated with Macugen (View Usage). Patient experienced the following unwanted or unexpected effects: eye haemorrhage. Macugen dosage: Intraocular. During the same period patient was treated with MARCUMAR (View Marcumar Review and Marcumar Label ), LEVOTHYROXINE SODIUM (View Levothyroxine Sodium Review and Levothyroxine Sodium Label ).

6479839-7 | Condition Aggravated, Macular Oedema, Retinal Haemorrhage, Retinal Vein Occlusion
on Nov 16, 2009 Male patient from JAPAN , 60 years of age, was diagnosed with choroidal neovascularisation and was treated with Macugen (View Usage). Patient had the following side effects: condition aggravated, macular oedema, retinal haemorrhage, retinal vein occlusion. Macugen dosage: 0.3mg, Intraocular. During the same period patient was treated with LEVOFLOXACIN (View Levofloxacin Review and Levofloxacin Label ), TRIAMCINOLONE ACETONIDE (View Triamcinolone Acetonide Review and Triamcinolone Acetonide Label ), BENOXIL (OXYBUPROCAINE) (View Benoxil (oxybuprocaine) Review and Benoxil (oxybuprocaine) Label ), POVIDONE IODINE (View Povidone Iodine Review and Povidone Iodine Label ).

6472484-9 | Myocardial Infarction
Patient was taking Macugen (View Usage). After Macugen was administered, patient had the following side effects: myocardial infarction on Nov 12, 2009 from JAPAN Additional patient health information: Female patient , 76 years of age, . Macugen dosage: 0.3 Mg, Intraocular. During the same period patient was treated with LEVOFLOXACIN (View Levofloxacin Review and Levofloxacin Label ), BROMFENAC SODIUM (BROMFENAC SODIUM) (View Bromfenac Sodium (bromfenac Sodium) Review and Bromfenac Sodium (bromfenac Sodium) Label ). Patient was hospitalized.

6463548-4 | Prostatic Specific Antigen Increased
Adverse event was reported on Nov 05, 2009 by a Male patient taking Macugen (View Usage) (Dosage: 0.3mg, Unk, Intraocular) was diagnosed with choroidal neovascularisation and. Location: JAPAN , 72 years of age, Patient experienced the following unwanted or unexpected effects: prostatic specific antigen increased. During the same period patient was treated with ADONA (CARBAZOCHROME SODIUM SULFONATE) (View Adona (carbazochrome Sodium Sulfonate) Review and Adona (carbazochrome Sodium Sulfonate) Label ), CARNACULIN (PANCREAS EXTRACT) (View Carnaculin (pancreas Extract) Review and Carnaculin (pancreas Extract) Label ), LEVOFLOXACIN (View Levofloxacin Review and Levofloxacin Label ).

6463543-5 | Retinal Vein Occlusion
on Nov 05, 2009 Male patient from JAPAN , 60 years of age, was diagnosed with choroidal neovascularisation and was treated with Macugen (View Usage). Patient had the following side effects: retinal vein occlusion. Macugen dosage: 0.3 Mg, Intraocular. During the same period patient was treated with LEVOFLOXACIN (View Levofloxacin Review and Levofloxacin Label ), TRIAMCINOLONE ACETONIDE (View Triamcinolone Acetonide Review and Triamcinolone Acetonide Label ).

6463542-3 | Ocular Hypertension, Visual Impairment
on Nov 06, 2009 Male patient from JAPAN , 60 years of age, was treated with Macugen (View Usage). After Macugen was administered, patient had the following side effects: ocular hypertension, visual impairment. Macugen dosage: . During the same period patient was treated with ISODINE (POVIDONE IODINE) (View Isodine (povidone-iodine) Review and Isodine (povidone-iodine) Label ), XYLOCAINE (View Xylocaine Review and Xylocaine Label ), GATIFLOXACIN (View Gatifloxacin Review and Gatifloxacin Label ), MEIACT (CEFDITOREN PIVOXIL) (View Meiact (cefditoren Pivoxil) Review and Meiact (cefditoren Pivoxil) Label ), MYDRIN P (PHENYLEPHRINE HYDROCHLORIDE, TROPICAMIDE) (View Mydrin P (phenylephrine Hydrochloride, Tropicamide) Review and Mydrin P (phenylephrine Hydrochloride, Tropicamide) Label ).

6447351-7 | Myocardial Infarction
Patient was taking Macugen (View Usage). Patient experienced the following unwanted or unexpected effects: myocardial infarction on Oct 29, 2009 from JAPAN Additional patient health information: Female patient , 76 years of age, . Macugen dosage: Intraocular. Patient was hospitalized.

6443757-0 | Ocular Hypertension
Adverse event was reported on Oct 26, 2009 by a Male patient taking Macugen (View Usage) (Dosage: (0.3mg), Intra-vitreal) . Location: JAPAN , 67 years of age, Patient had the following side effects: ocular hypertension. During the same period patient was treated with GATIFLOXACIN (View Gatifloxacin Review and Gatifloxacin Label ).

6437597-6 | Cerebral Infarction, Pallor
on Oct 21, 2009 Male patient from JAPAN , 81 years of age, weighting 121.5 lb, was treated with Macugen (View Usage). After Macugen was administered, patient had the following side effects: cerebral infarction, pallor. Macugen dosage: 0.3mg, Single. During the same period patient was treated with XYLOCAINE (View Xylocaine Review and Xylocaine Label ), BENOXIL (OXYBUPROCAINE) (View Benoxil (oxybuprocaine) Review and Benoxil (oxybuprocaine) Label ). Patient was hospitalized.

6428214-X | Atrial Fibrillation
on Sep 04, 2009 Female patient from JAPAN , 78 years of age, was treated with Macugen (View Usage). Patient experienced the following unwanted or unexpected effects: atrial fibrillation (What is atrial fibrillation?). Macugen dosage: Intraocular. Patient was hospitalized.

6409650-4 | Detachment Of Retinal Pigment Epithelium, Disease Progression, Injection Site Reaction, Nervous System Disorder, Retinal Vascular Disorder
Patient was taking Macugen (View Usage). Patient had the following side effects: detachment of retinal pigment epithelium, disease progression, injection site reaction, nervous system disorder, retinal vascular disorder on Oct 16, 2009 from ITALY Additional patient health information: Female patient , 66 years of age, . Macugen dosage: .

6408916-1 | Retinal Detachment
Adverse event was reported on Oct 16, 2009 by a Male patient taking Macugen (View Usage) (Dosage: 0.3mg, Intraocular) was diagnosed with choroidal neovascularisation and. Location: JAPAN , 87 years of age, After Macugen was administered, patient had the following side effects: retinal detachment. During the same period patient was treated with POVIDONE IODINE (View Povidone Iodine Review and Povidone Iodine Label ), CHLORHEXIDINE GLUCONATE (View Chlorhexidine Gluconate Review and Chlorhexidine Gluconate Label ), BENOXIL (OXYBUPROCAINE) (View Benoxil (oxybuprocaine) Review and Benoxil (oxybuprocaine) Label ), XYLOCAINE (View Xylocaine Review and Xylocaine Label ), LEVOFLOXACIN (View Levofloxacin Review and Levofloxacin Label ).

6405175-0 | Intraocular Pressure Increased
on Sep 25, 2009 Male patient from JAPAN , 77 years of age, weighting 153.2 lb, was treated with Macugen (View Usage). Patient experienced the following unwanted or unexpected effects: intraocular pressure increased. Macugen dosage: 0.3mg Intraocular. During the same period patient was treated with GATIFLOXACIN (View Gatifloxacin Review and Gatifloxacin Label ), ISODINE (POVIDONE IODINE) (View Isodine (povidone-iodine) Review and Isodine (povidone-iodine) Label ), ALLOPURINOL (View Allopurinol Review and Allopurinol Label ), CANDESARTAN CILEXETIL (View Candesartan Cilexetil Review and Candesartan Cilexetil Label ), ISOSORBIDE DINITRATE (View Isosorbide Dinitrate Review and Isosorbide Dinitrate Label ), CONIEL (BENIDIPINE HYDROCHLORIDE) (View Coniel (benidipine Hydrochloride) Review and Coniel (benidipine Hydrochloride) Label ), PRAVASTATIN (View Pravastatin Review and Pravastatin Label ), NATRIX (INDAPAMIDE) (View Natrix (indapamide) Review and Natrix (indapamide) Label ).

6401499-1 | Amaurosis
on Sep 24, 2009 Female patient from FRANCE , 83 years of age, was treated with Macugen (View Usage). Patient had the following side effects: amaurosis. Macugen dosage: .

6388919-6 | Cerebrovascular Accident, Slipping Rib Syndrome
Patient was taking Macugen (View Usage). After Macugen was administered, patient had the following side effects: cerebrovascular accident, slipping rib syndrome on Sep 18, 2009 from FRANCE Additional patient health information: Female patient , 95 years of age, . Macugen dosage: 1 Every 6 Weeks, Intraocular. During the same period patient was treated with ACETYLSALICYLATE LYSINE (ACETYLSALICYLATE LYSINE) (View Acetylsalicylate Lysine (acetylsalicylate Lysine) Review and Acetylsalicylate Lysine (acetylsalicylate Lysine) Label ), SIMVASTATIN (View Simvastatin Review and Simvastatin Label ), AMLODIPINE (View Amlodipine Review and Amlodipine Label ), GALENIC /BENAZEPRIL/HYDROCHLOROTHIAZIDE/ (View Galenic /benazepril/hydrochlorothiazide/ Review and Galenic /benazepril/hydrochlorothiazide/ Label ). Patient was hospitalized and became disabled.

6381438-2 | Endophthalmitis
Adverse event was reported on Sep 24, 2009 by a Male patient taking Macugen (View Usage) (Dosage: ) was diagnosed with maculopathy and. Location: JAPAN , 83 years of age, Patient experienced the following unwanted or unexpected effects: endophthalmitis. During the same period patient was treated with AVASTIN (View Avastin Review and Avastin Label ), BENOXIL (OXYBUPROCAINE) (View Benoxil (oxybuprocaine) Review and Benoxil (oxybuprocaine) Label ), GATIFLOXACIN (View Gatifloxacin Review and Gatifloxacin Label ), LEVOFLOXACIN (View Levofloxacin Review and Levofloxacin Label ). Patient was hospitalized.

6372052-3 | Cerebral Infarction
on Sep 01, 2009 Male patient from JAPAN , 83 years of age, was treated with Macugen (View Usage). Patient had the following side effects: cerebral infarction. Macugen dosage: 0.3mg, Single, Intraocular. During the same period patient was treated with XYLOCAINE (View Xylocaine Review and Xylocaine Label ).

6366379-9 | Endophthalmitis
on Aug 31, 2009 Male patient from JAPAN , 83 years of age, was diagnosed with maculopathy and was treated with Macugen (View Usage). After Macugen was administered, patient had the following side effects: endophthalmitis. Macugen dosage: . During the same period patient was treated with AVASTIN (View Avastin Review and Avastin Label ), BENOXIL (OXYBUPROCAINE) (View Benoxil (oxybuprocaine) Review and Benoxil (oxybuprocaine) Label ), GATIFLOXACIN (View Gatifloxacin Review and Gatifloxacin Label ), LEVOFLOXACIN (View Levofloxacin Review and Levofloxacin Label ). Patient was hospitalized.

6358958-X | Intraocular Pressure Increased
Patient was taking Macugen (View Usage). Patient experienced the following unwanted or unexpected effects: intraocular pressure increased on Aug 27, 2009 from JAPAN Additional patient health information: Male patient , 77 years of age, weighting 153.2 lb, . Macugen dosage: 0.3mg Intraocular. During the same period patient was treated with GATIFLOXACIN (View Gatifloxacin Review and Gatifloxacin Label ), ISODINE (POVIDONE IODINE) (View Isodine (povidone-iodine) Review and Isodine (povidone-iodine) Label ), ALLOPURINOL (View Allopurinol Review and Allopurinol Label ), CANDESARTAN CILEXETIL (View Candesartan Cilexetil Review and Candesartan Cilexetil Label ), ISOSORBIDE DINITRATE (View Isosorbide Dinitrate Review and Isosorbide Dinitrate Label ), CONIEL (BENIDIPINE HYDROCHLORIDE) (View Coniel (benidipine Hydrochloride) Review and Coniel (benidipine Hydrochloride) Label ), PRAVASTATIN (View Pravastatin Review and Pravastatin Label ), NATRIX (INDAPAMIDE) (View Natrix (indapamide) Review and Natrix (indapamide) Label ).

6355728-3 | Endophthalmitis
Adverse event was reported on Aug 25, 2009 by a Male patient taking Macugen (View Usage) (Dosage: ) . Location: JAPAN , 83 years of age, Patient had the following side effects: endophthalmitis. During the same period patient was treated with AVASTIN (View Avastin Review and Avastin Label ), BENOXIL (OXYBUPROCAINE) (View Benoxil (oxybuprocaine) Review and Benoxil (oxybuprocaine) Label ), GATIFLOXACIN (View Gatifloxacin Review and Gatifloxacin Label ), LEVOFLOXACIN (View Levofloxacin Review and Levofloxacin Label ). Patient was hospitalized.

6354372-1 | Alanine Aminotransferase Increased, Haematocrit Decreased, Haemoglobin Decreased, Mean Cell Haemoglobin Decreased, Mean Cell Volume Decreased, Red Blood Cell Count Decreased, Red Blood Cell Sedimentation Rate Increased, Vitreous Haemorrhage
on Aug 20, 2009 Female patient from INDIA , 61 years of age, weighting 167.6 lb, was treated with Macugen (View Usage). After Macugen was administered, patient had the following side effects: alanine aminotransferase increased, haematocrit decreased, haemoglobin decreased, mean cell haemoglobin decreased, mean cell volume decreased, red blood cell count decreased, red blood cell sedimentation rate increased, vitreous haemorrhage. Macugen dosage: 0.3 Mg Every 6 Wks, Intraocular. During the same period patient was treated with INJECTION HUMAN INSULIN (INSULIN HUMAN) (View Injection Human Insulin (insulin Human) Review and Injection Human Insulin (insulin Human) Label ), GLIMADAY (GLIMEPIRIDE, METFORMIN) (View Glimaday (glimepiride, Metformin) Review and Glimaday (glimepiride, Metformin) Label ), AMLODIPINE (View Amlodipine Review and Amlodipine Label ), MULTIVITAMINS (ASCORBIC ACID, ERGOCALCIFEROL, FOLIC ACID, NICOTINAMIDE (View Multivitamins (ascorbic Acid, Ergocalciferol, Folic Acid, Nicotinamide Review and Multivitamins (ascorbic Acid, Ergocalciferol, Folic Acid, Nicotinamide Label ), PANTOPRAZOLE (PANTOPRAZOLE) TABLET (View Pantoprazole (pantoprazole) Tablet Review and Pantoprazole (pantoprazole) Tablet Label ), ATORVASTATIN (View Atorvastatin Review and Atorvastatin Label ), TROPICAMIDE (View Tropicamide Review and Tropicamide Label ), PROPARACAINE ( PROMETACAINE) (View Proparacaine ( Prometacaine) Review and Proparacaine ( Prometacaine) Label ). Patient was hospitalized.

6348280-X |
on Aug 19, 2009 Male patient from JAPAN , 81 years of age, weighting 106.5 lb, was treated with Macugen (View Usage). . Macugen dosage: 0.3 Mg.

6348263-X |
Patient was taking Macugen (View Usage). on Aug 19, 2009 from JAPAN Additional patient health information: Female patient , 77 years of age, weighting 111.3 lb, was diagnosed with choroidal neovascularisation and. Macugen dosage: 0.3 Mg, Intraocular.