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1.5 million people annually are harmed from drug errors.
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From simple mix-ups to fatal overdoses, medication mistakes happen, on average, once a day to every hospital patient, a new report says. Nationwide, at least 1.5 million people annually are harmed from drug errors, more than half of them in nursing homes.
Many Unfavorable Drug Studies Aren’t Published. Nearly a third of antidepressant drug studies are never published in the medical literature, and nearly all of those happen to show that the drug being tests failed to work.
Only Drugs That are Safe Should be put on the Market. Drug developers are just beginning to come to grips with recent FDA oversight reforms and how they will affect drug safety. But, it appears that industry and consumer advocates are not together on how well the overhaul will be able to prevent future drug safety scandals.

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Review Metalyse Safety Reports submitted to FDA

Total Metalyse reports: 22.
Metalyse FDA safety alerts: No.
Reported deaths: 52    Reported hospitalizations: 1.
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FDA Reported Metalyse Side Effects: death, sudden death, angina pectoris, myocardial infarction, infarction, cerebral haemorrhage, pancreatitis haemorrhagic, ventricular fibrillation, respiratory tract infection, cardiogenic shock, cardiac failure.
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Metalyse Side Effects Report #5610948-8
Physician from INDIA reported METALYSE problem on Jan 28, 2008. Male patient, 67 years of age, was diagnosed with acute myocardial infarction and was treated with METALYSE. After drug was administered, patient experienced the following problems/side effects: cardiac arrest. METALYSE dosage: 0.5 MG/KG, UNK. During the same period patient was treated with HEPARIN. Patient died on 12/31/2007.

Metalyse Side Effects Report #5615517-1
METALYSE problem was reported by a Physician from GERMANY on Feb 04, 2008. Female patient was diagnosed with acute myocardial infarction and was treated with METALYSE. METALYSE dosage: unknown. During the same period patient was treated with ASPIRIN, ENOXAPARIN. Patient died.

Metalyse Side Effects Report #5615806-0
Physician from INDIA reported METALYSE problem on Jan 28, 2008. Male patient, 67 years of age, was diagnosed with acute myocardial infarction and was treated with METALYSE. After drug was administered, patient experienced the following problems/side effects: cardiac arrest. METALYSE dosage: 0.5 MG/KG, UNK. During the same period patient was treated with HEPARIN. Patient died on 12/31/2007.

Metalyse Side Effects Report #5587547-X
METALYSE problem was reported by a Physician from SINGAPORE on Jan 03, 2008. Male patient, 67 years of age, was diagnosed with acute myocardial infarction and was treated with METALYSE. After drug was administered, patient experienced the following problems/side effects: cardiac arrest. METALYSE dosage: 40 MG, UNK. During the same period patient was treated with HEPARIN. Patient died on 12/31/2007.

Metalyse Side Effects Report #5534849-9
Physician from GERMANY reported METALYSE problem on Nov 16, 2007. Male patient, 61 years of age, weighting 209.4 lb, was diagnosed with pulmonary embolism and was treated with METALYSE. After drug was administered, patient experienced the following problems/side effects: bradycardia, cardiac arrest. METALYSE dosage: 150 MG, UNK. Patient died.

Metalyse Side Effects Report #5548606-0
METALYSE problem was reported by a Physician from SINGAPORE on Dec 10, 2007. Male patient, 67 years of age, was diagnosed with acute myocardial infarction and was treated with METALYSE. After drug was administered, patient experienced the following problems/side effects: cardiac arrest. METALYSE dosage: 40 MG, UNK. Patient died on 09/28/2007.

Metalyse Side Effects Report #5517704-X
Physician from GERMANY reported METALYSE problem on Nov 02, 2007. Female patient was diagnosed with pulmonary embolism and was treated with METALYSE. METALYSE dosage: 150 MG, UNK. Patient died.

Metalyse Side Effects Report #5482308-4
METALYSE problem was reported by a Physician from SINGAPORE on Oct 08, 2007. Male patient, 67 years of age, was diagnosed with acute myocardial infarction and was treated with METALYSE. After drug was administered, patient experienced the following problems/side effects: circulatory collapse. METALYSE dosage: 40 MG, UNK. Patient died on 09/28/2007.

Metalyse Side Effects Report #5487170-1
Physician from SINGAPORE reported METALYSE problem on Oct 10, 2007. Male patient, 67 years of age, was diagnosed with acute myocardial infarction and was treated with METALYSE. After drug was administered, patient experienced the following problems/side effects: cardiac arrest. METALYSE dosage: 40 MG, UNK. Patient died on 09/28/2007.

Metalyse Side Effects Report #5491517-X
METALYSE problem was reported by a Consumer or non-health professional from FRANCE on Oct 15, 2007. Male patient, 46 years of age, was diagnosed with acute myocardial infarction and was treated with METALYSE. After drug was administered, patient experienced the following problems/side effects: acute coronary syndrome, acute myocardial infarction, alanine aminotransferase increased, areflexia, aspartate aminotransferase increased, blood albumin decreased, blood lactic acid increased, blood pressure decreased, brain compression. METALYSE dosage: unknown. During the same period patient was treated with LOVENOX, ASPEGIC, KARDEGIC, PLAVIX, SECTRAL, AMLOR, FOZITEC, LESCOL. Patient was hospitalized. Patient died on 05/30/2007.

Metalyse Side Effects Report #5402413-8
Consumer or non-health professional from SINGAPORE reported METALYSE problem on July 24, 2007. Male patient, 84 years of age, was treated with METALYSE. METALYSE dosage: 40 MG, 30 MG AS IV BOLUS. During the same period patient was treated with ENOXAPARIN. Patient died on 07/21/2007.

Metalyse Side Effects Report #5407106-9
METALYSE problem was reported by a Consumer or non-health professional from SINGAPORE on July 31, 2007. Male patient, 84 years of age, was diagnosed with acute myocardial infarction and was treated with METALYSE. After drug was administered, patient experienced the following problems/side effects: myocardial infarction. METALYSE dosage: 40 MG, 30 MG AS IV BOLUS. During the same period patient was treated with ENOXAPARIN. Patient died on 07/21/2007.

Metalyse Side Effects Report #5385884-5
Physician from AUSTRALIA reported METALYSE problem on July 09, 2007. Female patient was diagnosed with ischaemic stroke and was treated with METALYSE. METALYSE dosage: 0.9 MG/KG, UNK. Patient died.

Metalyse Side Effects Report #5395638-1
METALYSE problem was reported by a Physician from KOREA, REPUBLIC OF on July 20, 2007. Female patient was diagnosed with acute myocardial infarction and was treated with METALYSE. METALYSE dosage: unknown. Patient died.

Metalyse Side Effects Report #5395643-5
Physician from KOREA, REPUBLIC OF reported METALYSE problem on July 20, 2007. Male patient, 73 years of age, was diagnosed with acute myocardial infarction and was treated with METALYSE. After drug was administered, patient experienced the following problems/side effects: infarction. METALYSE dosage: 35 MG, UNK. Patient died on 09/30/2004.

Metalyse Side Effects Report #5395711-8
METALYSE problem was reported by a Physician from KOREA, REPUBLIC OF on July 19, 2007. Female patient, 58 years of age, was diagnosed with cardio-respiratory arrest and was treated with METALYSE. METALYSE dosage: unknown. Patient died on 11/01/2004.

Metalyse Side Effects Report #5395744-1
Physician from KOREA, REPUBLIC OF reported METALYSE problem on July 19, 2007. Female patient was treated with METALYSE. METALYSE dosage: unknown. Patient died on 08/01/2006.

Metalyse Side Effects Report #5385884-5
METALYSE problem was reported by a Physician from AUSTRALIA on July 09, 2007. Female patient was diagnosed with ischaemic stroke and was treated with METALYSE. METALYSE dosage: 0.9 MG/KG, UNK. Patient died.

Metalyse Side Effects Report #5395638-1
Physician from KOREA, REPUBLIC OF reported METALYSE problem on July 20, 2007. Female patient was diagnosed with acute myocardial infarction and was treated with METALYSE. METALYSE dosage: unknown. Patient died.

Metalyse Side Effects Report #5395643-5
METALYSE problem was reported by a Physician from KOREA, REPUBLIC OF on July 20, 2007. Male patient, 73 years of age, was diagnosed with acute myocardial infarction and was treated with METALYSE. After drug was administered, patient experienced the following problems/side effects: infarction. METALYSE dosage: 35 MG, UNK. Patient died on 09/30/2004.

Metalyse Side Effects Report #5395711-8
Physician from KOREA, REPUBLIC OF reported METALYSE problem on July 19, 2007. Female patient, 58 years of age, was diagnosed with cardio-respiratory arrest and was treated with METALYSE. METALYSE dosage: unknown. Patient died on 11/01/2004.

Metalyse Side Effects Report #5395744-1
METALYSE problem was reported by a Physician from KOREA, REPUBLIC OF on July 19, 2007. Female patient was treated with METALYSE. METALYSE dosage: unknown. Patient died on 08/01/2006.


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