Methotrexate Side Effects
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Methotrexate Safety Reports submitted to FDA
Total Methotrexate reports: 548.Methotrexate FDA safety alerts: 2005 2006 .
Reported deaths: 162 Reported hospitalizations: 191.
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Reported Methotrexate Side Effects: mucosal inflammation, pyrexia, pancytopenia, bone marrow failure, myelopathy, renal failure acute, neurotoxicity, nausea, anaemia, treatment related secondary malignancy, convulsion.
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Methotrexate Side Effects Report #5357275-4Health Professional from JAPAN reported METHOTREXATE problem on May 28, 2007. Male patient, 25 years of age, weighting 150.6 lb, was diagnosed with t-cell type acute leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: blood bilirubin increased, cerebral haemorrhage, convulsion, hemiparesis, superior sagittal sinus thrombosis. METHOTREXATE dosage: 15 MG, UNK, INTRATHECAL. During the same period patient was treated with PREDNISOLONE, CYTRABIN, VINCRISTINE, CYCLOPHOSPHAMIDE, MITOXANTRONE. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5357906-9
METHOTREXATE problem was reported by a Consumer or non-health professional from UNITED STATES on May 25, 2007. Male patient, 72 years of age, weighting 185.0 lb, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: hypersensitivity. METHOTREXATE dosage: unknown. During the same period patient was treated with FOLIC ACID, FOSAMAX, PREPARATION H, BENADRYL, CADUET, LISINOPRIL, ISOSORBIDE DINITRATE, WARFARIN. Patient recovered.
Methotrexate Side Effects Report #5358247-6
Physician from UNITED STATES reported METHOTREXATE problem on June 05, 2007. Male patient, 22 years of age, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: dysplastic naevus syndrome, malignant melanoma in situ. METHOTREXATE dosage: unknown. During the same period patient was treated with DAUNORUBICIN HYDROCHLORIDEECITON USP, ASPARAGINASE, PREDNISONE, MERCAPTOPURINE, CYTOXAN. Patient recovered.
Methotrexate Side Effects Report #5360042-9
METHOTREXATE problem was reported by a Consumer or non-health professional from UNITED STATES on May 30, 2007. Female patient, 69 years of age, weighting 170.0 lb, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: chest pain, cough, ear discomfort, ear pain, gait disturbance, hallucination, visual, headache, intraocular pressure increased, lip blister. METHOTREXATE dosage: unknown. During the same period patient was treated with FOLIC ACID. Patient recovered.
Methotrexate Side Effects Report #5361314-4
Physician from AUSTRALIA reported METHOTREXATE problem on June 06, 2007. Male patient, 25 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: areflexia, bk virus infection, bone marrow disorder, cerebral haemorrhage, cerebral infarction, csf protein increased, febrile neutropenia, gastrointestinal haemorrhage, graft versus host disease. METHOTREXATE dosage: unknown. During the same period patient was treated with CYTARABINE. Patient was hospitalized and became disabled. Patient recovered.
Methotrexate Side Effects Report #5363026-X
METHOTREXATE problem was reported by a Consumer or non-health professional from UNITED STATES on June 07, 2007. Male patient, 17 years of age, was diagnosed with bone sarcoma, metastases to lung, metastasis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: haemoglobin decreased, melaena, metastases to bone, metastases to lung, metastases to stomach, obliterative bronchiolitis, osteosarcoma metastatic, syncope, tumour necrosis. METHOTREXATE dosage: unknown. During the same period patient was treated with DOXORUBICIN, IFOSFAMIDE, CISPLATIN. Patient recovered.
Methotrexate Side Effects Report #5364287-3
Consumer or non-health professional from ITALY reported METHOTREXATE problem on June 05, 2007. Male patient, 64 years of age, was diagnosed with mantle cell lymphoma and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: disease progression. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE, DOXORUBICIN, CYTARABINE, DEXAMETHASONE, CYCLOPHOSPHAMIDE, IMATINIB MESYLATE, FLUDARABINE PHOSPHATE, RITUXIMAB. Patient died.
Methotrexate Side Effects Report #5364302-7
METHOTREXATE problem was reported by a Consumer or non-health professional from UNITED KINGDOM on June 05, 2007. Male patient, 67 years of age, weighting 198.0 lb, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: cardiac failure congestive, dyspnoea. METHOTREXATE dosage: 20 MG SC. During the same period patient was treated with RITUXIMAB, FOLIC ACID. Patient was hospitalized. Patient died.
Methotrexate Side Effects Report #5364637-8
Health Professional from UNITED STATES reported METHOTREXATE problem on May 10, 2007. Male patient, 20 years of age, weighting 249.1 lb, was diagnosed with neoplasm malignant and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: renal failure. METHOTREXATE dosage: 4.5MG/M2. During the same period patient was treated with RESPIRIDINE, AMLODIPINE, ONDANSETRON, PREDNISONE, INSULIN ASPART, ADDERALL. Patient recovered.
Methotrexate Side Effects Report #5368344-7
METHOTREXATE problem was reported by a Consumer or non-health professional from GERMANY on June 04, 2007. Female patient, 63 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: anorexia, nausea, nutritional condition abnormal, oral intake reduced, parosmia, vomiting, weight decreased. METHOTREXATE dosage: unknown. During the same period patient was treated with CORTICOSTEROIDS, VINCRISTINE, CYCLOPHOSPHAMIDE, CYTARABINE, IMATINIB MESYLATE. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5368412-X
Health Professional from JAPAN reported METHOTREXATE problem on June 08, 2007. Male patient, 25 years of age, weighting 150.6 lb, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: blood bilirubin increased, brain oedema, cerebral haemorrhage, convulsion, hemiplegia, loss of consciousness, superior sagittal sinus thrombosis. METHOTREXATE dosage: 15 MG, 8 DOSES, INTRATHECAL. During the same period patient was treated with PREDNISOLONE, CYTARABINE, ADRIAMYCIN PFS, VINCRISTINE, CYCLOPHOSPHAMIDE, MITOXANTRONE. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5368535-5
METHOTREXATE problem was reported by a Health Professional from FRANCE on June 04, 2007. Female patient, 16 years of age, was diagnosed with bone sarcoma and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: blood pressure increased, convulsion, cytolytic hepatitis, mucosal inflammation, renal failure, renal tubular disorder, thrombocytopenia. METHOTREXATE dosage: unknown. During the same period patient was treated with DANTROLENE, ONDANESTRON, METHYLPREDNISOLONE, NALBUPHINE. Patient recovered.
Methotrexate Side Effects Report #5368913-4
Pharmacist from UNITED STATES reported METHOTREXATE problem on June 21, 2007. Male patient, weighting 110.2 lb, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, anxiety, brain scan abnormal, confusional state, delirium, demyelination, electroencephalogram abnormal, epilepsy, flight of ideas. METHOTREXATE dosage: 15 MG X3 IT. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5371703-X
METHOTREXATE problem was reported by a Consumer or non-health professional from FINLAND on June 25, 2007. Female patient, 65 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: brain stem haemorrhage, disorder of orbit, ischaemia, mucormycosis. METHOTREXATE dosage: unknown. During the same period patient was treated with PREDNISONE, ADALIMUMAB. Patient was hospitalized. Patient died.
Methotrexate Side Effects Report #5372051-4
Consumer or non-health professional from UNITED KINGDOM reported METHOTREXATE problem on June 12, 2007. Male patient, 62 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: cardiac failure, pneumonitis. METHOTREXATE dosage: 20 MG FREQ. During the same period patient was treated with MABTHERA. Patient died on 01/01/2007.
Methotrexate Side Effects Report #5372808-X
METHOTREXATE problem was reported by a Consumer or non-health professional from UNITED STATES on June 11, 2007. Male patient, 60 years of age, was diagnosed with arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: anorexia, anuria, autonomic nervous system imbalance, escherichia sepsis, haematemesis, haemodialysis, hypotension, nausea. METHOTREXATE dosage: 10MG WEEKLY SUBCUTANEOUS. Patient was hospitalized. Patient died.
Methotrexate Side Effects Report #5373458-1
Health Professional from AUSTRALIA reported METHOTREXATE problem on June 25, 2007. Male patient, child 8 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: b-lymphocyte count decreased, hair growth abnormal, hypogammaglobulinaemia, rash, respiratory tract infection viral. METHOTREXATE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, VINCRISTINE SULPHATE, IDARUBICIN, ASPARAGINASE, CYTARABINE, DEXAMETHASONE, MERCAPTOPURINE. Patient recovered.
Methotrexate Side Effects Report #5374155-9
METHOTREXATE problem was reported by a Consumer or non-health professional from GERMANY on June 19, 2007. Female patient, 75 years of age, was diagnosed with arthropathy, rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: bone marrow failure, bone marrow toxicity, glossitis, odynophagia, oral mucosal petechiae, pancytopenia, pneumonia, sepsis. METHOTREXATE dosage: 15 MG WEEKLY;. During the same period patient was treated with AMINOGLYCOSIDE. Patient died.
Methotrexate Side Effects Report #5375387-6
Consumer or non-health professional from CZECH REPUBLIC reported METHOTREXATE problem on June 13, 2007. Female patient, 82 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: bone marrow failure, bronchopneumonia, febrile neutropenia, pancytopenia. METHOTREXATE dosage: 10 MG/WEEK ORAL. During the same period patient was treated with MONOSAN, MOLSIHEXAL RETARD, MANINIL, VASOCARDIN, ENAP, LIPANOR, WARFARIN, FURON. Patient died.
Methotrexate Side Effects Report #5376394-X
METHOTREXATE problem was reported by a Consumer or non-health professional from UNITED STATES on June 27, 2007. Male patient, weighting 31.75 lb, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: activated partial thromboplastin time prolonged, blood glucose decreased, blood pressure diastolic decreased, haemoglobin decreased, heart rate increased, hypothermia, peripheral coldness, prothrombin time prolonged, somnolence. METHOTREXATE dosage: 100 MG. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5044410-0
Health Professional from ITALY reported METHOTREXATE problem on June 26, 2006. Female patient, 77 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: lymphoproliferative disorder, non-hodgkin's lymphoma, treatment related secondary malignancy. METHOTREXATE dosage: unknown. During the same period patient was treated with CYCLOSPORINE, ENBREL. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5046109-3
METHOTREXATE problem was reported by a Consumer or non-health professional from UNITED STATES on July 07, 2006. Male patient, weighting 109.1 lb, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: asthenia, cerebral ischaemia, cerebrovascular accident, hypoaesthesia, infarction, muscular weakness. METHOTREXATE dosage: unknown. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5047261-6
Consumer or non-health professional from FRANCE reported METHOTREXATE problem on June 19, 2006. Female patient, 49 years of age, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: aphasia, aplasia, bone marrow failure, brain oedema, candida sepsis, cerebral haematoma, cerebral haemorrhage, enterobacter sepsis. METHOTREXATE dosage: unknown. During the same period patient was treated with DOXORUBICIN, VINCRISTINE, MABTHERA, ETOPOSIDE, CYCLOPHOSPHAMIDE, CYTARABINE. Patient was hospitalized. Patient died.
Methotrexate Side Effects Report #5048772-X
METHOTREXATE problem was reported by a Consumer or non-health professional from UNITED KINGDOM on June 19, 2006. Female patient, 73 years of age, weighting 99.21 lb, was diagnosed with rheumatoid arthritis, osteoporosis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: gastritis, mouth ulceration, pancytopenia. METHOTREXATE dosage: 20 MG OTH. During the same period patient was treated with RISEDRONATE, CALCICHEW D, ACETAMINOPHEN. Patient recovered.
Methotrexate Side Effects Report #5050302-3
Consumer or non-health professional from reported METHOTREXATE problem on June 27, 2006. Female patient, 64 years of age, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: pancytopenia, pyrexia, stomatitis. METHOTREXATE dosage: unknown. Patient died.
Methotrexate Side Effects Report #5050901-9
METHOTREXATE problem was reported by a Consumer or non-health professional from on June 27, 2006. Male patient, 52 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: blood arsenic increased, cognitive disorder, gliosis, leukoencephalopathy, memory impairment. METHOTREXATE dosage: 12 MG/DOSE, TR. During the same period patient was treated with ARSENIC TRIOXIDE, TRETINOIN, ASCORBIC ACID, CYTARABINE. Patient recovered.
Methotrexate Side Effects Report #5051509-1
Health Professional from UNITED STATES reported METHOTREXATE problem on June 27, 2006. Female patient was diagnosed with ectopic pregnancy and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: diarrhoea haemorrhagic, multi-organ failure, oral pain. METHOTREXATE dosage: 20 MG/M2 X 1 DOSE (NR, ONCE) IM. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5052426-3
METHOTREXATE problem was reported by a Consumer or non-health professional from UNITED STATES on July 14, 2006. Male patient, weighting 109.1 lb, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: asthenia, cerebral infarction, cerebral ischaemia, cerebrovascular accident, muscular weakness. METHOTREXATE dosage: 45 MG. During the same period patient was treated with VINCRISTINE SULPHATE, CYTARABINE, DOXORUBICIN HYDROCHLORIDE. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5052509-8
Pharmacist from UNITED STATES reported METHOTREXATE problem on July 13, 2006. Male patient, 81 years of age, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: blood creatine phosphokinase increased, blood pressure abnormal, cardiac arrest, cholecystectomy, colostomy, diarrhoea, diverticular perforation, faecal incontinence, fall. METHOTREXATE dosage: 15 MILLIGRAMS QWEEKLY PO. Patient died on 06/09/2006.
Methotrexate Side Effects Report #5052814-5
METHOTREXATE problem was reported by a Pharmacist from UNITED STATES on July 13, 2006. Female patient, 63 years of age, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: acute myocardial infarction, cardio-respiratory arrest, hypoaesthesia, hypotension, renal failure acute, sepsis, ventricular tachycardia. METHOTREXATE dosage: unknown. Patient died on 06/13/2006.
Methotrexate Side Effects Report #5053096-0
Pharmacist from UNITED STATES reported METHOTREXATE problem on Apr 05, 2004. Male patient, 17 years of age, weighting 152.1 lb, was diagnosed with bone sarcoma and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: chemical burn of skin. METHOTREXATE dosage: unknown. During the same period patient was treated with BICARBONATE, KYTRIL, BENADRYL, DECADRON SRC, PHENERGAN, ATIVAN, ZANTAC. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5053392-7
METHOTREXATE problem was reported by a Consumer or non-health professional from UNITED KINGDOM on June 16, 2006. Female patient, 53 years of age, was diagnosed with myositis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: bursitis, c-reactive protein increased, joint effusion, mycobacterial infection, neutrophil count increased, osteoarthritis, synovial cyst, synovial disorder. METHOTREXATE dosage: 10 MG DAILY IM. During the same period patient was treated with CYCLOSPORINE, PREDNISOLONE. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5053438-6
Health Professional from AUSTRIA reported METHOTREXATE problem on June 28, 2006. Female patient, 33 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: immunodeficiency, lymphopenia. METHOTREXATE dosage: 25 MG WEEKLY INJ. During the same period patient was treated with AKTIFERRIN, CYCLACOR, DICLOFENAC, FOLIC ACID, FOSAMAX, KEPPRA, MEXALEN, PREDNISOLONE. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5053443-X
METHOTREXATE problem was reported by a Health Professional from UNITED KINGDOM on June 28, 2006. Female patient, 74 years of age, was diagnosed with breast cancer and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: lower respiratory tract infection, neutropenic sepsis. METHOTREXATE dosage: 80 MG ONCE IV. During the same period patient was treated with FLUOROURACIL, CYCLOPHOSPHAMIDE, ASPIRIN, DIAZEPAM, HYDROXOCOBALAMIN, LANSOPRAZOLE, SIMVASTATIN. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5054213-9
Consumer or non-health professional from reported METHOTREXATE problem on July 03, 2006. Male patient, 70 years of age, was diagnosed with psoriatic arthropathy and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: abdominal discomfort, activated partial thromboplastin time prolonged, ascites, aspartate aminotransferase increased, blood albumin decreased, blood creatinine increased, blood urea increased, bone marrow failure, c-reactive protein increased. METHOTREXATE dosage: 7.5 TO 15 MG PER WEEK. During the same period patient was treated with FOLATE, MELOXICAM, CARVEDILOL, MODURETICS, AMILORIDE HYDROCHLORIDE, HYDROCHLOROTHIAZIDE, RAMIPRIL, CLOPIDOGREL. Patient was hospitalized. Patient died.
Methotrexate Side Effects Report #5055288-3
METHOTREXATE problem was reported by a Physician from JAPAN on July 04, 2006. Female patient, 33 years of age, weighting 108.0 lb, was diagnosed with bone sarcoma and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, back pain. METHOTREXATE dosage: unknown. During the same period patient was treated with MEYLON, DIAMOX, NEOPHAGEN. Patient recovered.
Methotrexate Side Effects Report #5055359-1
Consumer or non-health professional from KOREA, DEMOCRATIC PEOPLE'S REPUBLIC OF reported METHOTREXATE problem on July 07, 2006. Female patient, 46 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: anaplastic large cell lymphoma t- and null-cell types, ascites, costovertebral angle tenderness, dyspnoea, haemoglobin decreased, hepatosplenomegaly, lymphadenopathy, lymphadenopathy mediastinal, pleural effusion. METHOTREXATE dosage: unknown. During the same period patient was treated with FOLIC ACID, SULFASALAZINE, HYDROXYCHLOROQUINE SULPHATE. Patient recovered.
Methotrexate Side Effects Report #5055462-6
METHOTREXATE problem was reported by a Health Professional from PERU on July 11, 2006. Male patient, 64 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: pneumocystis jiroveci pneumonia, respiratory failure. METHOTREXATE dosage: 15 MG - 1XW - ORAL. During the same period patient was treated with ORENCIA, REMICADE, PREDNISONE, IBUPROFEN, RANITIDINE, CAPTOPRIL, CALCIUM CARBONATE. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5055774-6
Health Professional from UNITED STATES reported METHOTREXATE problem on July 02, 2006. Male patient, 66 years of age, was diagnosed with psoriasis, psoriatic arthropathy and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: bacillary angiomatosis, haemangioma, haemorrhage, malignant histiocytosis, nodule, psoriasis, rash erythematous, rash pruritic. METHOTREXATE dosage: unknown. During the same period patient was treated with CALCIPOTRIENE, FLUOCINONIDE. Patient recovered.
Methotrexate Side Effects Report #5058478-9
METHOTREXATE problem was reported by a Health Professional from ZAIRE on July 13, 2006. Female patient, 57 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: abscess soft tissue, bacterial infection. METHOTREXATE dosage: 15 MG - ORAL. During the same period patient was treated with ORENCIA, REMICADE, PREDNISONE, FOLIC ACID, VELTEX. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5059063-5
Consumer or non-health professional from UNITED STATES reported METHOTREXATE problem on July 13, 2006. Female patient was diagnosed with ectopic pregnancy and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: diarrhoea haemorrhagic, oral pain. METHOTREXATE dosage: 50 MG/M2 IM. Patient recovered.
Methotrexate Side Effects Report #5060087-2
METHOTREXATE problem was reported by a Physician from JAPAN on July 11, 2006. Female patient, 33 years of age, was diagnosed with bone sarcoma and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, back pain, erythema. METHOTREXATE dosage: unknown. During the same period patient was treated with NEOPHAGEN. Patient recovered.
Methotrexate Side Effects Report #5060203-2
Consumer or non-health professional from UNITED KINGDOM reported METHOTREXATE problem on July 13, 2006. Female patient, 33 years of age, was diagnosed with scleritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: oedema peripheral, paraesthesia, pruritus, swelling face, urticaria. METHOTREXATE dosage: 10 MG 1XW - PO. During the same period patient was treated with PREDNISOLONE. Patient recovered.
Methotrexate Side Effects Report #5060624-8
METHOTREXATE problem was reported by a Pharmacist from UNITED STATES on July 20, 2006. Female patient was diagnosed with rheumatoid arthritis, staphylococcal infection and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: bone marrow failure, staphylococcal infection, stomatitis. METHOTREXATE dosage: 7.5MG Q WEEK PO. During the same period patient was treated with BACTRIM DS. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5060699-6
Consumer or non-health professional from UNITED STATES reported METHOTREXATE problem on July 20, 2006. Female patient, weighting 26.46 lb, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: abdominal pain, activated partial thromboplastin time prolonged, agitation, atelectasis, brain herniation, brain oedema, cerebellar infarction, cerebral disorder, cerebral haemorrhage. METHOTREXATE dosage: unknown. Patient was hospitalized. Patient died.
Methotrexate Side Effects Report #5063419-4
METHOTREXATE problem was reported by a Health Professional from POLAND on July 17, 2006. Male patient, 35 years of age, was diagnosed with psoriatic arthropathy and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: haemangioma. METHOTREXATE dosage: unknown. During the same period patient was treated with CYCLOSPORINE, METHYLPREDNISOLONE. Patient recovered.
Methotrexate Side Effects Report #5063593-X
Health Professional from FRANCE reported METHOTREXATE problem on July 17, 2006. Female patient, 48 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: non-hodgkin's lymphoma. METHOTREXATE dosage: unknown. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5065234-4
METHOTREXATE problem was reported by a Health Professional from UNITED KINGDOM on July 17, 2006. Female patient, 14 years of age, was diagnosed with arthropathy, juvenile arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: arthroscopy. METHOTREXATE dosage: 25 MG WEEKLY SC. During the same period patient was treated with ENBREL, FELDENE. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5066022-5
Pharmacist from UNITED STATES reported METHOTREXATE problem on July 31, 2006. Female patient, 42 years of age, weighting 144.0 lb, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: cryptogenic organising pneumonia, interstitial lung disease, respiratory distress. METHOTREXATE dosage: 20MG WEEKLY PO. During the same period patient was treated with HUMALOG, LEVAQUIN, ZOCOR, GLUCOPHAGE, HYDROCHLOROTHIAZIDE, GLUCOTROL, PREDNISONE. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5066845-2
METHOTREXATE problem was reported by a Consumer or non-health professional from on July 05, 2006. Female patient, 77 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: abdominal mass, blood lactate dehydrogenase increased, diffuse large b-cell lymphoma, fatigue, hepatomegaly, hyperhidrosis, lymphadenopathy, lymphoproliferative disorder, non-hodgkin's lymphoma. METHOTREXATE dosage: 15 MG PER WEEK (1 IN 1 WK),. During the same period patient was treated with CYCLOSPORINE, CHLOROQUINE, SULFASALAZINE, RITUXIMAB, LEFLUNOMIDE, ENBREL. Patient recovered.
Methotrexate Side Effects Report #5067127-5
Health Professional from ITALY reported METHOTREXATE problem on July 18, 2006. Female patient, 63 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: bladder cancer. METHOTREXATE dosage: 7.5 MG WEEKLY IM. During the same period patient was treated with HUMIRA, MEDROL, OMEPRAZEN, URSODEOXYCHOLIC ACID, COLECALCIFEROL. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5067129-9
METHOTREXATE problem was reported by a Consumer or non-health professional from UNITED KINGDOM on July 17, 2006. Female patient, child 9 years of age, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: nausea, panic disorder. METHOTREXATE dosage: unknown. During the same period patient was treated with ENBREL, IBUPROFEN. Patient recovered.
Methotrexate Side Effects Report #5067263-3
Health Professional from ITALY reported METHOTREXATE problem on July 20, 2006. Female patient, 25 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: uterine leiomyoma. METHOTREXATE dosage: 10 MG WEEKLY IM. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5069135-7
METHOTREXATE problem was reported by a Physician from UNITED STATES on July 18, 2006. Male patient, 15 years of age, weighting 122.4 lb, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: blood luteinising hormone decreased, epiphysiolysis, growth hormone deficiency, insulin-like growth factor decreased. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE, DEXAMETHASONE, DOXORUBICIN, MERCAPTOPURINE, CYCLOPHOSPHAMIDE, ELSPAR, CYTARABINE, THIOGUANINE. Patient recovered.
Methotrexate Side Effects Report #5070018-7
Consumer or non-health professional from UNITED KINGDOM reported METHOTREXATE problem on July 18, 2006. Male patient, 25 years of age, weighting 204.1 lb, was diagnosed with crohn's disease and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: breast mass, gynaecomastia. METHOTREXATE dosage: 17.5 MG FREQ IM. During the same period patient was treated with ASACOL, FOLIC ACID, LANSOPROAZOLE, PREDNISOLONE. Patient recovered.
Methotrexate Side Effects Report #5069646-4
METHOTREXATE problem was reported by a Pharmacist from UNITED STATES on Aug 02, 2006. Male patient, 63 years of age, weighting 201.6 lb, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: interstitial lung disease. METHOTREXATE dosage: unknown. Patient recovered.
Methotrexate Side Effects Report #5069654-3
Health Professional from UNITED STATES reported METHOTREXATE problem on Aug 02, 2006. Female patient, 19 years of age, weighting 135.0 lb, was diagnosed with ectopic pregnancy and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: abortion spontaneous, asthenia, asthma, chemical injury, condition aggravated, cough, haematocrit decreased, haemoglobin decreased. METHOTREXATE dosage: 3.70 ML X1 IM. Patient recovered.
Methotrexate Side Effects Report #5071429-6
METHOTREXATE problem was reported by a Pharmacist from UNITED STATES on Aug 03, 2006. Female patient, 76 years of age, weighting 99.21 lb, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: anaemia, mouth ulceration, neutropenia, oedema peripheral, toxic epidermal necrolysis. METHOTREXATE dosage: 7.5 MG WEEKLY PO. Patient recovered.
Methotrexate Side Effects Report #5072965-9
Consumer or non-health professional from SWITZERLAND reported METHOTREXATE problem on July 18, 2006. Male patient, 63 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: polyneuropathy. METHOTREXATE dosage: 25 MG WEEKLY SC. Patient recovered.
Methotrexate Side Effects Report #5074763-9
METHOTREXATE problem was reported by a Health Professional from GERMANY on July 26, 2006. Male patient, 42 years of age, was diagnosed with psoriatic arthropathy and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: coronary artery disease, myocardial infarction. METHOTREXATE dosage: 10 MG WEEKLY PR A FEW YEARS. During the same period patient was treated with ENBREL, MOBIC, PREDNISOLONE, FOLIC ACID. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5074764-0
Health Professional from ITALY reported METHOTREXATE problem on July 27, 2006. Female patient, 63 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: bladder cancer. METHOTREXATE dosage: 7.5 MG WEEKLY IM. During the same period patient was treated with HUMIRA, MEDROL, OMEPRAZEN, URSODEOXYCHOLIC ACID, COLECALCIFEROL, NERIXIA. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5080332-7
METHOTREXATE problem was reported by a Health Professional from INDIA on Aug 07, 2006. Female patient, 17 years of age, was diagnosed with stem cell transplant and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in intestine, acute graft versus host disease in skin, alanine aminotransferase increased, aspartate aminotransferase increased, bladder disorder, blood bilirubin increased, blood creatinine increased, blood culture positive, blood lactate dehydrogenase increased. METHOTREXATE dosage: unknown. During the same period patient was treated with METHYLPREDNISOLONE, CYCLOSPORINE. Patient was hospitalized. Patient died.
Methotrexate Side Effects Report #5080794-5
Health Professional from UNITED STATES reported METHOTREXATE problem on July 31, 2006. Female patient, 15 years of age, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: arthritis, condition aggravated, upper respiratory tract infection. METHOTREXATE dosage: 25 MG WEEKLY SC. During the same period patient was treated with ENBREL. Patient recovered.
Methotrexate Side Effects Report #5080799-4
METHOTREXATE problem was reported by a Consumer or non-health professional from UNITED KINGDOM on July 28, 2006. Female patient, 73 years of age, weighting 99.21 lb, was diagnosed with rheumatoid arthritis, osteoporosis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: blood disorder, gastritis, mouth ulceration, pancytopenia. METHOTREXATE dosage: 20 MG WEEKLY. During the same period patient was treated with RISEDRONATE, CALCICHEW D, ACETAMINOPHEN. Patient recovered.
Methotrexate Side Effects Report #5080886-0
Health Professional from FRANCE reported METHOTREXATE problem on Aug 02, 2006. Female patient, 22 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: abortion spontaneous, pregnancy. METHOTREXATE dosage: 7.5 MG WEEKLY IM. During the same period patient was treated with ENBREL, CORTANCYL, SPECIAFOLDINE. Patient recovered.
Methotrexate Side Effects Report #5081214-7
METHOTREXATE problem was reported by a Health Professional from INDIA on Aug 07, 2006. Female patient, 17 years of age, was diagnosed with stem cell transplant and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, blood creatinine increased, blood lactate dehydrogenase increased, blood urea increased, chills, escherichia infection. METHOTREXATE dosage: unknown. During the same period patient was treated with METHYLPREDNISOLONE, CYCLOSPORINE. Patient was hospitalized. Patient died.
Methotrexate Side Effects Report #5081606-6
Health Professional from BRAZIL reported METHOTREXATE problem on Aug 07, 2006. Female patient, 51 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: anal cancer, rectal cancer. METHOTREXATE dosage: 20 MG - 1XW - ORAL. During the same period patient was treated with REMICADE, FOLIC ACID, PREDNISONE, RANITIDINE, AMLODIPINE, METHYLDOPA, CAPTOPRIL. Patient recovered.
Methotrexate Side Effects Report #5081607-8
METHOTREXATE problem was reported by a Health Professional from ZAIRE on Aug 07, 2006. Female patient, 57 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: abscess soft tissue, bacterial infection. METHOTREXATE dosage: 15 MG - ORAL. During the same period patient was treated with PREDNISONE, FOLIC ACID, VELTEX. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5082196-4
Pharmacist from UNITED STATES reported METHOTREXATE problem on Aug 15, 2006. Male patient, 57 years of age, weighting 149.0 lb, was diagnosed with leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased. METHOTREXATE dosage: 360 MG/7.2 ML ONCE OVER 2H IV. During the same period patient was treated with BICARBONATE, CHLORHEXIDINE, ALUMINUM AND MAGNESIUM HYDROXIDE, ALUMINUM HYDROXIDE, NYSTATIN, ACETAMINOPHEN, DIPHENHYDRAMINE. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5082369-0
METHOTREXATE problem was reported by a Consumer or non-health professional from UNITED STATES on July 31, 2006. Female patient, child 12 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: growth hormone deficiency. METHOTREXATE dosage: unknown. During the same period patient was treated with MERCAPTOPURINE, CYCLOPHOSPHAMIDE, DEXAMETHASONE, VINCRISTINE, ADRIAMYCIN PFS, ELSPAR, CYTARABINE. Patient recovered.
Methotrexate Side Effects Report #5082370-7
Consumer or non-health professional from UNITED STATES reported METHOTREXATE problem on July 31, 2006. Male patient, 15 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: blood luteinising hormone decreased, epiphysiolysis, growth hormone deficiency. METHOTREXATE dosage: unknown. During the same period patient was treated with MERCAPTOPURINE, CYCLOPHOSPHAMIDE, DEXAMETHASONE, VINCRISTINE, ADRIAMYCIN PFS, ELSPAR, CYTARABINE. Patient recovered.
Methotrexate Side Effects Report #5082442-7
METHOTREXATE problem was reported by a Health Professional from SPAIN on Aug 07, 2006. Female patient, 79 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: non-hodgkin's lymphoma. METHOTREXATE dosage: unknown. During the same period patient was treated with SULFASALAZINE, HYDROCHLOROTHIAZIDE. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5083645-8
Health Professional from JAPAN reported METHOTREXATE problem on Aug 14, 2006. Female patient, 71 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: epstein-barr virus infection, pancytopenia. METHOTREXATE dosage: unknown. During the same period patient was treated with PREDNISOLONE. Patient recovered.
Methotrexate Side Effects Report #5084666-1
METHOTREXATE problem was reported by a Health Professional from UNITED STATES on Aug 14, 2006. Female patient, 70 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: non-hodgkin's lymphoma, treatment related secondary malignancy. METHOTREXATE dosage: unknown. Patient recovered.
Methotrexate Side Effects Report #5087573-3
Health Professional from JAPAN reported METHOTREXATE problem on June 23, 2006. Female patient, 35 years of age, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: c-reactive protein increased, disorientation, fatigue, hyperaesthesia, hyperkalaemia, neuralgia, paraesthesia, pneumonia bacterial, pruritus. METHOTREXATE dosage: 10 MG/M2/D. During the same period patient was treated with ACYCLOVIR, MICAFUNGIN, MEROPENEM, VANCOMYCIN, NEUPOGEN, MYCOPHENOLATE MOFETIL, SANDIMMUNE. Patient was hospitalized. Patient died on 01/02/2004.
Methotrexate Side Effects Report #5087842-7
METHOTREXATE problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 21, 2006. Male patient, weighting 32.85 lb, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: acute respiratory distress syndrome, bacillus infection, bilirubin conjugated increased, cerebral haemorrhage, disease progression, dysstasia, encephalopathy, glioma. METHOTREXATE dosage: 10 MG. During the same period patient was treated with VINCRISTINE SULPHATE, VINCRISTINE SULPHATE, VINCRISTINE SULPHATE, VINCRISTINE SULPHATE, DAUNORUBICIN. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5087924-X
Health Professional from UNITED STATES reported METHOTREXATE problem on Aug 23, 2006. Female patient, weighting 152.0 lb, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: convulsion, respiratory arrest. METHOTREXATE dosage: 20 MG A WEEK PO. During the same period patient was treated with ENBREL, HYDROXYCHLOROQUINE SULPHATE, SULFASALAZINE, PREDNISONE, LISINOPRIL, ROBITTUSIN AC. Patient died on 05/24/2006.
Methotrexate Side Effects Report #5091213-7
METHOTREXATE problem was reported by a Pharmacist from UNITED STATES on Aug 25, 2006. Male patient, 18 years of age, weighting 174.2 lb, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: ischaemic stroke. METHOTREXATE dosage: unknown. During the same period patient was treated with CYTARABINE, NAFCILLIN IV, CEFTAZADIME IV, CAFFEINE BENZOATE. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5091704-9
Consumer or non-health professional from reported METHOTREXATE problem on Aug 11, 2006. Female patient, 50 years of age, was diagnosed with burkitt's lymphoma, febrile neutropenia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: febrile neutropenia, pneumonia, pseudomonas infection. METHOTREXATE dosage: unknown. During the same period patient was treated with PIPERACILLIN, TAZOBACTAM. Patient recovered.
Methotrexate Side Effects Report #5091895-X
METHOTREXATE problem was reported by a Consumer or non-health professional from on Aug 11, 2006. Female patient, 79 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: b-cell lymphoma, dislocation of vertebra, epstein-barr virus test positive, fistula, gingival ulceration, mouth ulceration, non-hodgkin's lymphoma, palatal disorder, purulent discharge. METHOTREXATE dosage: 7.5 MG/WEEK (, 1 IN 1 WK). During the same period patient was treated with SULFASALAZINE, HYDROCHLOROTHIAZIDE. Patient recovered.
Methotrexate Side Effects Report #5093463-2
Health Professional from UNITED KINGDOM reported METHOTREXATE problem on Feb 22, 2005. Female patient, child 7 years of age, was diagnosed with juvenile arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: full blood count decreased, lymphocyte count decreased. METHOTREXATE dosage: 9 MG WEEKLY SC. During the same period patient was treated with ENBREL. Patient recovered.
Methotrexate Side Effects Report #5096695-2
METHOTREXATE problem was reported by a Consumer or non-health professional from on Aug 17, 2006. Male patient, 35 years of age, was diagnosed with psoriatic arthropathy and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: condition aggravated, gingival hyperplasia, haemangioma. METHOTREXATE dosage: 17.5 MG/WEEK (1 IN 1 WK). During the same period patient was treated with METHYLPREDNISOLONE, CYCLOSPORINE. Patient recovered.
Methotrexate Side Effects Report #5096696-4
Consumer or non-health professional from reported METHOTREXATE problem on Aug 23, 2006. Female patient was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: beta 2 microglobulin increased, c-reactive protein increased, hypoxia, lung injury, lymphocyte count decreased, pyrexia, respiratory distress. METHOTREXATE dosage: unknown. During the same period patient was treated with NSAIDS, PREDNISOLONE. Patient died.
Methotrexate Side Effects Report #5097380-3
METHOTREXATE problem was reported by a Physician from UNITED STATES on Aug 18, 2006. Female patient, 58 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: chest pain, dyspnoea, hepatic enzyme increased, pancreatitis. METHOTREXATE dosage: unknown. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5099434-4
Pharmacist from UNITED STATES reported METHOTREXATE problem on Sept 05, 2006. Female patient, 90 years of age, weighting 117.0 lb, was diagnosed with cardiac failure congestive and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: cough, diarrhoea, dyspnoea, malaise, pharyngolaryngeal pain, rash, stomatitis. METHOTREXATE dosage: 10 MG (4X 2.5 MG TAB) ONCE DAILY PO. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5099452-6
METHOTREXATE problem was reported by a Health Professional from UNITED KINGDOM on Aug 28, 2006. Female patient, 61 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: arrhythmia, interstitial lung disease, metabolic acidosis, renal failure. METHOTREXATE dosage: unknown. During the same period patient was treated with ENBREL. Patient was hospitalized. Patient died.
Methotrexate Side Effects Report #5099951-7
Health Professional from JAPAN reported METHOTREXATE problem on Aug 28, 2006. Female patient, 61 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: diffuse large b-cell lymphoma, treatment related secondary malignancy. METHOTREXATE dosage: unknown. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5100613-8
METHOTREXATE problem was reported by a Consumer or non-health professional from UNITED STATES on Sept 07, 2006. Male patient, weighting 32.85 lb, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: bilirubin conjugated increased, blood culture positive, cerebral haemorrhage, cerebral ischaemia, cough, encephalopathy, hepatosplenomegaly, hypercalcaemia. METHOTREXATE dosage: 10 MG. During the same period patient was treated with VINCRISTINE SULPHATE, DAUNORUBICIN, DEXAMETHASONE. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5101310-5
Health Professional from KOREA, REPUBLIC OF reported METHOTREXATE problem on Sept 05, 2006. Female patient, 46 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: t-cell lymphoma, treatment related secondary malignancy. METHOTREXATE dosage: DOSE WAS 7.5-12.5 MG PER WEEK WITH A TOTAL DOSE OF 1742 MG.. During the same period patient was treated with FOLIC ACID, SULFASALAZINE, HYDROXYCHLOROQUINE SULPHATE, SULINDAC, PREDNISOLONE. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5101951-5
METHOTREXATE problem was reported by a Physician from UNITED STATES on Aug 28, 2006. Female patient, 22 years of age, weighting 110.0 lb, was diagnosed with ectopic pregnancy and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: acute respiratory distress syndrome, bone marrow failure, diarrhoea haemorrhagic, lung injury, mucosal inflammation, multi-organ disorder, oral pain, transaminases increased. METHOTREXATE dosage: 50 MG/M2 ONCE IM. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5102305-8
Health Professional from NETHERLANDS reported METHOTREXATE problem on Sept 05, 2006. Male patient, 29 years of age, was diagnosed with neoplasm and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: dialysis, neutropenia, pericardial haemorrhage, renal failure, staphylococcal bacteraemia, thrombocytopenia. METHOTREXATE dosage: unknown. Patient died.
Methotrexate Side Effects Report #5102733-0
METHOTREXATE problem was reported by a Consumer or non-health professional from SWITZERLAND on Aug 22, 2006. Female patient, 57 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: malignant melanoma. METHOTREXATE dosage: 2.5 MILLIGRAM QW. During the same period patient was treated with FOLIC ACID, GLUCOSAMINE, FISH OIL. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5104219-6
Physician from JAPAN reported METHOTREXATE problem on Aug 24, 2006. Female patient, 71 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: aspiration bone marrow abnormal, blood lactate dehydrogenase increased, crepitations, epstein-barr virus infection, hip fracture, infectious mononucleosis, lymphadenopathy, lymphocytosis, lymphoproliferative disorder. METHOTREXATE dosage: SEE TEXT 8 MG, 1 IN 1 WK). During the same period patient was treated with PREDNISOLONE. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5104248-2
METHOTREXATE problem was reported by a Health Professional from UNITED KINGDOM on Aug 30, 2006. Male patient, 75 years of age, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: acute myocardial infarction, alveolitis, cardiogenic shock, cardiopulmonary failure, infection, pneumocystis jiroveci pneumonia, pneumonitis. METHOTREXATE dosage: 10 MG WEEKLY PO. During the same period patient was treated with OMEPRAZOLE, DICLOFENAC, FOLIC ACID, PREDNISOLONE, ATORVASTATIN, PERINDOPRIL ERBUMINE, LEFLUNOMIDE. Patient was hospitalized. Patient died on 01/20/2005.
Methotrexate Side Effects Report #5106455-1
Consumer or non-health professional from UNITED KINGDOM reported METHOTREXATE problem on Aug 29, 2006. Female patient, 66 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: pulmonary fibrosis. METHOTREXATE dosage: 20 MG - 1XW - PO. During the same period patient was treated with LEFLUNOMIDE, PARACETAMOL, ETORICOXIB, FOLIC ACID, OMEPRAZOLE. Patient died.
Methotrexate Side Effects Report #5106904-9
METHOTREXATE problem was reported by a Consumer or non-health professional from on Aug 30, 2006. Female patient, 61 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: arrhythmia, metabolic acidosis, pneumonitis, pulmonary fibrosis, renal failure. METHOTREXATE dosage: (25 MG). During the same period patient was treated with ENBREL. Patient was hospitalized. Patient died.
Methotrexate Side Effects Report #5106906-2
Consumer or non-health professional from reported METHOTREXATE problem on Aug 30, 2006. Female patient, 64 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: arthropathy, bullous lung disease, condition aggravated, interstitial lung disease, therapeutic response decreased. METHOTREXATE dosage: 22.5 MG/WEEK (22.5 MG). During the same period patient was treated with ENBREL. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5107002-0
METHOTREXATE problem was reported by a Consumer or non-health professional from on Sept 01, 2006. Female patient, 61 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: b-cell lymphoma, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, bone marrow disorder, haemoglobin decreased, lymphoproliferative disorder, mixed connective tissue disease, platelet count decreased, pulmonary hypertension. METHOTREXATE dosage: 5 TO 7.5 MGWEEK (NR, 1 IN 1 WK), NR. During the same period patient was treated with NSAIDS, STERIODS. Patient was hospitalized. Patient recovered.
Methotrexate Side Effects Report #5107662-4
Consumer or non-health professional from UNITED KINGDOM reported METHOTREXATE problem on Sept 11, 2006. Male patient, 75 years of age, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: acute myocardial infarction, alveolitis, cardiogenic shock, dyspnoea, infection, pneumonitis. METHOTREXATE dosage: 10 MG - 1XW - PO. During the same period patient was treated with OMEPRAZOLE, DICLOFENAC, FOLIC ACID, PREDNISOLONE, ATORVASTATIN, PERINDOPRIL ERBUMINE, LEFLUNOMIDE. Patient was hospitalized. Patient died on 01/20/2005.
Methotrexate Side Effects Report #5107698-3
METHOTREXATE problem was reported by a Consumer or non-health professional from on Sept 01, 2006. Female patient, 51 years of age, was diagnosed with acute promyelocytic leukaemia, nervous system disorder and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: c-reactive protein increased, extrasystoles, fatigue, hypokalaemia, hypomagnesaemia, pathogen resistance, pharyngitis, pyrexia, speech disorder. METHOTREXATE dosage: (15 MG), IT. During the same period patient was treated with ARSENIC TRIOXIDE, ARSENIC TRIOXIDE, CYTARABINE, PREDNISOLONE. Patient recovered.
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