Methylcobal Side Effects

Common Methylcobal Side Effects

The most commonly reported Methylcobal side effects (click to view or check a box to report):

Nystagmus (1)
Toxicity To Various Agents (1)
Speech Disorder (1)
Skin Ulcer (1)
Muscle Spasms (1)
Convulsion (1)
Dizziness (1)
Diarrhoea (1)
Cytomegalovirus Mucocutaneous Ulcer (1)
Sick Sinus Syndrome (1)
Renal Impairment (1)
Petechiae (1)
Off Label Use (1)
Oesophageal Candidiasis (1)
Pharyngitis (1)
Platelet Count Decreased (1)
Purpura (1)
Product Contamination Microbial (1)
Pneumonia Bacterial (1)
Areflexia (1)

➢ More

If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

Methylcobal Side Effects Reported to FDA

The following Methylcobal reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

The appearance of Methylcobal on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.
Diarrhoea, Headache, Product Contamination Microbial, Escherichia Infection
This is a report of a 56-year-old female patient (weight: NA) from US, suffering from the following symptoms/conditions: gene mutation, who was treated with Methylcobalamine/folinic Acid/ Hydroxocalbalamine/p5p (dosage: Iject 0.3 Once Daily Into The Muscle, start time: Aug 18, 2013), combined with: NA. and developed a serious reaction and side effect(s). The consumer presented with:
  • Diarrhoea
  • Headache
  • Product Contamination Microbial
  • Escherichia Infection
which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Methylcobalamine/folinic Acid/ Hydroxocalbalamine/p5p treatment in female patients, resulting in diarrhoea side effect.

Dizziness, Muscle Spasms, Fatigue, Dyspnoea, Hypoaesthesia
This report suggests a potential Methylcobalamin Dizziness, Muscle Spasms, Fatigue, Dyspnoea, Hypoaesthesia side effect(s) that can have serious consequences. A 38-year-old male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: multiple sclerosis and used Methylcobalamin (dosage: 0.5 Ml- 4 Times/week At Bedtime Into The Muscle) starting Nov 01, 2011. Soon after starting Methylcobalamin the patient began experiencing various side effects, including:
  • Dizziness
  • Muscle Spasms
  • Fatigue
  • Dyspnoea
  • Hypoaesthesia
Drugs used concurrently: NA. Although Methylcobalamin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as dizziness, may still occur.

Visual Impairment, Toxicity To Various Agents, Nystagmus, Areflexia, Memory Impairment, Speech Disorder, Convulsion, Incorrect Dose Administered
This Visual Impairment, Toxicity To Various Agents, Nystagmus, Areflexia, Memory Impairment, Speech Disorder, Convulsion, Incorrect Dose Administered problem was reported by a health professional from JAPAN. A 20-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Methylcobalamin (no Pref. Name) (dosage: 1.5 Mg). The following drugs were being taken at the same time:
  • Phenytoin (250 Mg)
When commencing Methylcobalamin (no Pref. Name), the patient experienced the following unwanted symptoms/side effects:
  • Visual Impairment
  • Toxicity To Various Agents
  • Nystagmus
  • Areflexia
  • Memory Impairment
  • Speech Disorder
  • Convulsion
  • Incorrect Dose Administered
The patient was hospitalized and became disabled.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as visual impairment, may become evident only after a product is in use by the general population.

Platelet Count Decreased, Off Label Use, Skin Ulcer, Purpura, Oesophageal Candidiasis, Pneumonia Bacterial, Herpes Dermatitis, Cytomegalovirus Mucocutaneous Ulcer
This is a report of a 75-year-old male patient (weight: NA) from JAPAN. The patient developed the following symptoms/conditions: NA and was treated with Methylcobal (mecobalamin) (dosage: NA) starting Jan 01, 2009. Concurrently used drugs:
  • Bonalon (alendronate Sodium)
  • Ganciclovir
  • Methylprednisolone (1 G, Iv Drip)
  • Prednisolone (15 Mg, Oral, 60 Mg, Oral, Oral, 6 Mg, Oral, 40 Mg, Oral, 11 Mg, Oral, 30 Mg, Oral, Oral)
  • Prednisolone (15 Mg, Oral, 60 Mg, Oral, Oral, 6 Mg, Oral, 40 Mg, Oral, 11 Mg, Oral, 30 Mg, Oral, Oral)
  • Prednisolone (15 Mg, Oral, 60 Mg, Oral, Oral, 6 Mg, Oral, 40 Mg, Oral, 11 Mg, Oral, 30 Mg, Oral, Oral)
  • Prednisolone (15 Mg, Oral, 60 Mg, Oral, Oral, 6 Mg, Oral, 40 Mg, Oral, 11 Mg, Oral, 30 Mg, Oral, Oral)
  • Itraconazole
Soon after that, the consumer experienced the following side effects:
  • Platelet Count Decreased
  • Off Label Use
  • Skin Ulcer
  • Purpura
  • Oesophageal Candidiasis
  • Pneumonia Bacterial
  • Herpes Dermatitis
  • Cytomegalovirus Mucocutaneous Ulcer
The patient was hospitalized. This opens a possibility that Methylcobal (mecobalamin) treatment could cause the above reactions, including platelet count decreased, and some male subjects may be more susceptible.

Pharyngitis, Increased Upper Airway Secretion, Petechiae
A 37-year-old female patient (weight: NA) from CHINA with the following symptoms/conditions: NA started Methylcobalamin/multivitamin treatment (dosage: Unk) on Jul 07, 2011. Soon after starting Methylcobalamin/multivitamin treatment, the subject experienced various side effects, including:
  • Pharyngitis
  • Increased Upper Airway Secretion
  • Petechiae
Concurrently used drugs:
  • Carbamazepine (Unk)
  • Lyrica (75 Mg, 2x/day)
This finding indicates that some female patients could be more vulnerable to Methylcobalamin/multivitamin.

Renal Impairment, Sick Sinus Syndrome
A female patient from JAPAN (weight: NA) experienced symptoms, such as: NA and was treated with Methylcobal(dosage: 1500 Mcg). The treatment was initiated on Nov 08, 2010. After that a consumer reported the following side effect(s):
  • Renal Impairment
  • Sick Sinus Syndrome
Concurrently used drugs, which potentially could have contributed to side effect(s) or affected Methylcobal efficacy:
  • Ketoprofen (1df)
  • Coniel (8 Mg)
  • Ketobun (100 Mg)
  • Pantosin (3 G)
  • Micombi Combination (Telmisartan 40 Mg/hydrochlorothiazide 12.5 Mg)
  • Escelase (3df)
  • Heavy Magnesium Oxide (1 G)
  • Uritos (0.1 Mg)
The patient was hospitalized.

Keep Track of Side Effects

Note Your Observations

It is really important to keep of your symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Discuss Methylcobal Side Effects

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