Common Metronidazole Side Effects


The most commonly reported Metronidazole side effects (click to view or check a box to report):

Dizziness (123)
Dysarthria (123)
Vomiting (119)
Nausea (107)
Encephalopathy (106)
Diarrhoea (102)
Paraesthesia (93)
Headache (88)
Confusional State (80)
Ataxia (80)
Toxic Encephalopathy (71)
Pruritus (67)
Gait Disturbance (62)
Pain (60)
Neuropathy Peripheral (60)
Pyrexia (58)
Cerebellar Syndrome (58)
Rash (56)
Urticaria (51)
Malaise (49)

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If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Metronidazole Side Effects Reported to FDA



Metronidazole Side Effect Report#9995149
Anaphylactic Reaction
This is a report of a 45-year-old male patient (weight: NA) from NZ, suffering from the following health symptoms/conditions: NA, who was treated with Metronidazole (metronidazole) (dosage: NA, start time: NS), combined with:
  • Cefuroxime
  • Gelofusine
and developed a serious reaction and side effect(s): Anaphylactic Reaction after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Metronidazole (metronidazole) treatment in male patients, resulting in Anaphylactic Reaction side effect.
Metronidazole Side Effect Report#9995139
Anaphylactic Reaction
This report suggests a potential Metronidazole (metronidazole) Anaphylactic Reaction side effect(s) that can have serious consequences. A 39-year-old male patient (weight: NA) from NZ was diagnosed with the following symptoms/conditions: NA and used Metronidazole (metronidazole) (dosage: NA) starting NS. After starting Metronidazole (metronidazole) the patient began experiencing various side effects, including: Anaphylactic ReactionAdditional drugs used concurrently:
  • Ibuprofen (ibuprofen)
Although Metronidazole (metronidazole) demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Anaphylactic Reaction, may still occur.
Metronidazole Side Effect Report#9994302
Pharyngeal Oedema
This Pharyngeal Oedema problem was reported by a health professional from GB. A 55-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Feb 17, 2014 this consumer started treatment with Metronidazole 500 Mg / 100 Ml Intravenous Infusion (dosage: NA). The following drugs were being taken at the same time: NA. When using Metronidazole 500 Mg / 100 Ml Intravenous Infusion, the patient experienced the following unwanted symptoms/side effects: Pharyngeal OedemaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Pharyngeal Oedema, may become evident only after a product is in use by the general population.
Metronidazole Side Effect Report#9994231
Anaphylactic Shock
This Anaphylactic Shock side effect was reported by a physician from GB. A 72-year-old male patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Metronidazole 500 Mg / 100 Ml Intravenous Infusion (drug dosage: NA), which was initiated on
Feb 05, 2014. Concurrently used drugs:
  • Amoxicillin
  • Gentamicin
  • Ondansetron
.After starting to take Metronidazole 500 Mg / 100 Ml Intravenous Infusion the consumer reported adverse symptoms, such as: Anaphylactic ShockThese side effects may potentially be related to Metronidazole 500 Mg / 100 Ml Intravenous Infusion.
Metronidazole Side Effect Report#9980792
Pharyngeal Oedema
This is a report of a 55-year-old female patient (weight: NA) from GB, suffering from the following health symptoms/conditions: NA, who was treated with Metronidazole (dosage: NA, start time:
Feb 17, 2014), combined with: NA. and developed a serious reaction and side effect(s): Pharyngeal Oedema after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Metronidazole treatment in female patients, resulting in Pharyngeal Oedema side effect.
Metronidazole Side Effect Report#9972973
Anxiety, Phobia
This report suggests a potential Metronidazole Anxiety side effect(s) that can have serious consequences. A 66-year-old male patient (weight: NA) from NL was diagnosed with the following symptoms/conditions: NA and used Metronidazole (dosage: 500 Mg, Tid) starting
Oct 31, 2013. After starting Metronidazole the patient began experiencing various side effects, including: Anxiety, PhobiaAdditional drugs used concurrently: NA. Although Metronidazole demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Anxiety, may still occur.
Metronidazole Side Effect Report#9971729
Sudden Hearing Loss, Tinnitus, Nervousness, Tenderness, Deafness Neurosensory, Pain In Extremity, Deafness Transitory
This Sudden Hearing Loss problem was reported by a health professional from Country Not Specified. A 23-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: diarrhoea. On NS this consumer started treatment with Metronidazole (dosage: NA). The following drugs were being taken at the same time: NA. When using Metronidazole, the patient experienced the following unwanted symptoms/side effects: Sudden Hearing Loss, Tinnitus, Nervousness, Tenderness, Deafness Neurosensory, Pain In Extremity, Deafness TransitoryThe patient was hospitalized and became disabled.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Sudden Hearing Loss, may become evident only after a product is in use by the general population.
Metronidazole Side Effect Report#9971292
Diarrhoea, Nausea, Headache, Depression, Frequent Bowel Movements, Dehydration, Dysstasia, Asthenia, Dizziness
This Diarrhoea side effect was reported by a consumer or non-health professional from US. A 65-year-old male patient (weight:NA) experienced the following symptoms/conditions: haemorrhoid operation,prophylaxis.The patient was prescribed Metronidazole (drug dosage: 1 Pill Twice Daily Taken By Mouth), which was initiated on
Feb 13, 2014. Concurrently used drugs: NA..After starting to take Metronidazole the consumer reported adverse symptoms, such as: Diarrhoea, Nausea, Headache, Depression, Frequent Bowel Movements, Dehydration, Dysstasia, Asthenia, DizzinessThese side effects may potentially be related to Metronidazole.
Metronidazole Side Effect Report#9958647
Oculogyric Crisis
This is a report of a 32-year-old female patient (weight: NA) from SG, suffering from the following health symptoms/conditions: NA, who was treated with Metronidazole (metronidazole) (dosage: NA, start time: NS), combined with:
  • Metoclopramide (metoclopramide)
  • Buscopan (hyoscine Butylbromide) (hyoscine Butylbromide)
and developed a serious reaction and side effect(s): Oculogyric Crisis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Metronidazole (metronidazole) treatment in female patients, resulting in Oculogyric Crisis side effect.
Metronidazole Side Effect Report#9937228
Feeling Drunk, Somnolence
This report suggests a potential Metronidazole Feeling Drunk side effect(s) that can have serious consequences. A 38-year-old male patient (weight: NA) from GB was diagnosed with the following symptoms/conditions: abscess drainage and used Metronidazole (dosage: 400 Mg, Bid) starting
Feb 05, 2014. After starting Metronidazole the patient began experiencing various side effects, including: Feeling Drunk, SomnolenceAdditional drugs used concurrently:
  • Co-amoxiclav
Although Metronidazole demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Feeling Drunk, may still occur.
Metronidazole Side Effect Report#9937223
Dyspnoea, Limb Discomfort, Feeling Abnormal, Feeling Of Body Temperature Change, Chest Discomfort, Asthenia, Anxiety, Nervousness, Dry Mouth
This Dyspnoea problem was reported by a health professional from GB. A 72-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: postoperative care. On
Jan 22, 2014 this consumer started treatment with Metronidazole (dosage: 400 Mg, Tid). The following drugs were being taken at the same time:
  • Paracetamol (800 Mg, 3-4 Times Daily)
When using Metronidazole, the patient experienced the following unwanted symptoms/side effects: Dyspnoea, Limb Discomfort, Feeling Abnormal, Feeling Of Body Temperature Change, Chest Discomfort, Asthenia, Anxiety, Nervousness, Dry MouthAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Dyspnoea, may become evident only after a product is in use by the general population.
Metronidazole Side Effect Report#9931652
Nausea, Malaise
This Nausea side effect was reported by a consumer or non-health professional from US. A 59-year-old female patient (weight:NA) experienced the following symptoms/conditions: infection.The patient was prescribed Metronidazole (drug dosage: NA), which was initiated on
Feb 13, 2014. Concurrently used drugs:
  • Flagyl
.After starting to take Metronidazole the consumer reported adverse symptoms, such as: Nausea, MalaiseThese side effects may potentially be related to Metronidazole.
Metronidazole Side Effect Report#9927824
Cholecystitis Acute, Anaemia
This is a report of a 24-year-old female patient (weight: NA) from PH, suffering from the following health symptoms/conditions: evidence based treatment, who was treated with Metronidazole (dosage: Intravenous (not Otherwise Specified), start time: NS), combined with:
  • Unacid (Intravenous (not Otherwise Specified))
and developed a serious reaction and side effect(s): Cholecystitis Acute, Anaemia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Metronidazole treatment in female patients, resulting in Cholecystitis Acute side effect. The patient was hospitalized.
Metronidazole Side Effect Report#9917228
Guillain-barre Syndrome, Radiculitis, Dizziness, Headache
This report suggests a potential Metronidazole Guillain-barre Syndrome side effect(s) that can have serious consequences. A 11-year-old male patient (weight: NA) from NL was diagnosed with the following symptoms/conditions: amoebiasis and used Metronidazole (dosage: 250 Mg, Tid - 3 Keer Per Dag 1.5 Stuk(s)) starting
Dec 31, 2013. After starting Metronidazole the patient began experiencing various side effects, including: Guillain-barre Syndrome, Radiculitis, Dizziness, HeadacheAdditional drugs used concurrently: NA. Although Metronidazole demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Guillain-barre Syndrome, may still occur.
Metronidazole Side Effect Report#9916137
Skin Irritation, Erythema, Pruritus, Dry Skin
This Skin Irritation problem was reported by a consumer or non-health professional from US. A 61-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: rosacea. On 201311 this consumer started treatment with Metronidazole (dosage: Apply Once Daily). The following drugs were being taken at the same time:
  • Estrogel
When using Metronidazole, the patient experienced the following unwanted symptoms/side effects: Skin Irritation, Erythema, Pruritus, Dry SkinAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Skin Irritation, may become evident only after a product is in use by the general population.
Metronidazole Side Effect Report#9916126
Androgenetic Alopecia, Condition Aggravated, Rash Pustular, Hyperaesthesia, Erythema
This Androgenetic Alopecia side effect was reported by a consumer or non-health professional from US. A 85-year-old female patient (weight:NA) experienced the following symptoms/conditions: rosacea.The patient was prescribed Metronidazole (drug dosage: Apply To Entire Face Qhs), which was initiated on 201311. Concurrently used drugs:
  • Synthroid
  • Omeprazole
  • Centrum
  • Dramanine
  • Temazepam
  • Lomotil
  • Baby Aspirin
.After starting to take Metronidazole the consumer reported adverse symptoms, such as: Androgenetic Alopecia, Condition Aggravated, Rash Pustular, Hyperaesthesia, ErythemaThese side effects may potentially be related to Metronidazole.
Metronidazole Side Effect Report#9914301
Acute Psychosis
This is a report of a 27-year-old female patient (weight: NA) from GB, suffering from the following health symptoms/conditions: bacterial vaginosis, who was treated with Metronidazole (dosage: About 5 Days., start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Acute Psychosis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Metronidazole treatment in female patients, resulting in Acute Psychosis side effect. The patient was hospitalized.
Metronidazole Side Effect Report#9914251
Haemorrhage, Erythema
This report suggests a potential Metronidazole (galderma Laboratories) Haemorrhage side effect(s) that can have serious consequences. A 80-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: rosacea and used Metronidazole (galderma Laboratories) (dosage: Unk Unk, Single) starting
Feb 03, 2014. After starting Metronidazole (galderma Laboratories) the patient began experiencing various side effects, including: Haemorrhage, ErythemaAdditional drugs used concurrently: NA. Although Metronidazole (galderma Laboratories) demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Haemorrhage, may still occur.
Metronidazole Side Effect Report#9913203
Hepatotoxicity, International Normalised Ratio Increased, Hepatic Failure, Hepatitis
This Hepatotoxicity problem was reported by a physician from GB. A 54-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: clostridium difficile colitis. On NS this consumer started treatment with Metronidazole (dosage: NA). The following drugs were being taken at the same time: NA. When using Metronidazole, the patient experienced the following unwanted symptoms/side effects: Hepatotoxicity, International Normalised Ratio Increased, Hepatic Failure, HepatitisThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Hepatotoxicity, may become evident only after a product is in use by the general population.
Metronidazole Side Effect Report#9912925
Confusional State, Logorrhoea, Dysarthria, Ataxia, Central Nervous System Lesion, Pressure Of Speech
This Confusional State side effect was reported by a physician from JP. A 67-year-old male patient (weight:NA) experienced the following symptoms/conditions: brain abscess.The patient was prescribed Metronidazole (drug dosage: NA), which was initiated on NS. Concurrently used drugs: NA..After starting to take Metronidazole the consumer reported adverse symptoms, such as: Confusional State, Logorrhoea, Dysarthria, Ataxia, Central Nervous System Lesion, Pressure Of SpeechThese side effects may potentially be related to Metronidazole.
Metronidazole Side Effect Report#9912757
Pharyngeal Oedema, Swollen Tongue, Dyspnoea, Vomiting, Diarrhoea, Proctalgia, Abdominal Pain Lower
This is a report of a 47-year-old female patient (weight: NA) from GB, suffering from the following health symptoms/conditions: back pain, who was treated with Metronidazole (dosage: NA, start time:
Jan 21, 2014), combined with: NA. and developed a serious reaction and side effect(s): Pharyngeal Oedema, Swollen Tongue, Dyspnoea, Vomiting, Diarrhoea, Proctalgia, Abdominal Pain Lower after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Metronidazole treatment in female patients, resulting in Pharyngeal Oedema side effect. The patient was hospitalized.
Metronidazole Side Effect Report#9912043
Acquired Porphyria
This report suggests a potential Metronidazole Injection, Usp Acquired Porphyria side effect(s) that can have serious consequences. A 23-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: pelvic inflammatory disease and used Metronidazole Injection, Usp (dosage: NA) starting NS. After starting Metronidazole Injection, Usp the patient began experiencing various side effects, including: Acquired PorphyriaAdditional drugs used concurrently:
  • Ceftriaxone
  • Doxycycline
The patient was hospitalized. Although Metronidazole Injection, Usp demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Acquired Porphyria, may still occur.
Metronidazole Side Effect Report#9892682
Dysphagia, Aspergillus Infection, Sepsis
This Dysphagia problem was reported by a health professional from US. A 86-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Metronidazole Injection, Usp Rtu? (dosage: NA). The following drugs were being taken at the same time:
  • Fluconazole Injection, Usp
  • Nystatin
  • Voriconazole
When using Metronidazole Injection, Usp Rtu?, the patient experienced the following unwanted symptoms/side effects: Dysphagia, Aspergillus Infection, SepsisAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Dysphagia, may become evident only after a product is in use by the general population.
Metronidazole Side Effect Report#9892566
Deafness Bilateral, Deafness Neurosensory, Tinnitus, Hypoacusis
This Deafness Bilateral side effect was reported by a health professional from IR. A 23-year-old female patient (weight:NA) experienced the following symptoms/conditions: blastocystis infection,diarrhoea.The patient was prescribed Metronidazole (drug dosage: 750 Mg, Tid), which was initiated on NS. Concurrently used drugs: NA..After starting to take Metronidazole the consumer reported adverse symptoms, such as: Deafness Bilateral, Deafness Neurosensory, Tinnitus, HypoacusisThese side effects may potentially be related to Metronidazole. The patient was hospitalized.
Metronidazole Side Effect Report#9892495
Pancytopenia
This is a report of a 52-year-old male patient (weight: NA) from FR, suffering from the following health symptoms/conditions: NA, who was treated with Metronidazole Baxter 0,5 Pour Cent, Solution Injectable En Poche (dosage: NA, start time:
Dec 29, 2013), combined with:
  • Bactrim Forte
  • Cefotaxime Panpharma
  • Kaletra
  • Retrovir
  • Ceftriaxone Sodium
  • Ziagen
  • Wellvone
  • Isentress
and developed a serious reaction and side effect(s): Pancytopenia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Metronidazole Baxter 0,5 Pour Cent, Solution Injectable En Poche treatment in male patients, resulting in Pancytopenia side effect. The patient was hospitalized.


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The appearance of Metronidazole on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

What are common Metronidazole Side Effects for Women?

Women Side Effects Reports
Nausea 87
Vomiting 86
Dizziness 85
Headache 69
Diarrhoea 68
Pruritus 56
Pain 54
Paraesthesia 52
Confusional State 51
Pyrexia 42

What are common Metronidazole Side Effects for Men?

Men Side Effects Reports
Dysarthria 80
Encephalopathy 57
Ataxia 49
Toxic Encephalopathy 49
Cerebellar Syndrome 39
Paraesthesia 39
Dizziness 37
Neuropathy Peripheral 31
Vomiting 31
Diarrhoea 30

Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Metronidazole reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

    Discuss Metronidazole Side Effects

    Did You Have a Metronidazole Side Effect?

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    Yes, Moderate
    Yes, Minor
    No

    How Effective is Metronidazole for You?

    Exceeded Expectations
    Effective
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    Metronidazole Safety Alerts, Active Ingredients, Usage Information

    NDC 0069-2390
    Type HUMAN PRESCRIPTION DRUG
    Proprietary Name Metronidazole
    Name Metronidazole
    Dosage Form INJECTION, SOLUTION
    Route INTRAVENOUS
    On market since 20081120
    Labeler Pfizer Labs, Division of Pfizer Inc
    Active Ingredient(s) METRONIDAZOLE
    Strength(s) 500
    Unit(s) mg/100mL
    Pharma Class Nitroimidazole Antimicrobial [EPC],Nitroimidazoles [Chemical/Ingredient]

    Metronidazole Dosage, Warnings, Usage.

    Side Effects reported to FDA: 1819

    Metronidazole safety alerts: 2011 2010

    Reported deaths: 133

    Reported hospitalizations: 682

    Metronidazole Tablets, 250mg: Recall - Underweight Tablets

    [Posted 01/06/2011]

    AUDIENCE: Pharmacy, Consumer

    ISSUE: Teva Pharmaceuticals and FDA notified healthcare professionals and the public of a recall of Metronidazole Tablets USP, 250mg, lot #312566, expiration date 05/2012. This product lot is being recalled due to the presence of underweight tablets. Underweight tablets may not contain the full amount of active ingredient within a single tablet, and a consumer may not receive the prescribed dose. This may cause the infection the drug was intended to treat to worsen or recur, which could be life-threatening when treating severe infections.

    BACKGROUND: Metronidazole is indicated for the treatment of symptomatic and asymptomatic trichomoniasis, and treatment of asymptomatic consorts, amebiasis and a variety of anaerobic bacterial infections. The affected Metronidazole lot is packaged in 250 count bottles and was distributed nationwide to wholesalers and retailers.

    RECOMMENDATION: Consumers who have lot 312566 in their possession are instructed to cease using the product and return it to their pharmacy.


    Healthcare professionals and patients are encouraged to report adverse events or side effects related to the use of these products to the FDA's MedWatch Safety Information and Adverse Event Reporting Program:

    • Complete and submit the report Online: www.fda.gov/MedWatch/report.htm
    • Download form or call 1-800-332-1088 to request a reporting form, then complete and return to the address on the pre-addressed form, or submit by fax to 1-800-FDA-0178

     


    [01/06/2011 - Press Release - Teva Pharmaceuticals, U.S.A]

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