MITOTANE Side Effects

6744462-3 | Abdominal Pain, Alanine Aminotransferase Increased, Fatigue, Gamma-glutamyltransferase Increased, Malaise, Vomiting
on May 25, 2010 Male patient from FRANCE , 67 years of age, was diagnosed with adrenocortical carcinoma and was treated with Mitotane (View Usage). Patient experienced the following unwanted or unexpected effects: abdominal pain (What is abdominal pain?), alanine aminotransferase increased, fatigue, gamma-glutamyltransferase increased, malaise, vomiting. Mitotane dosage: Reduced To 1.5gm. During the same period patient was treated with CORTONE ACETATE (1.25 Df= (1/2+1/2+1/4)) (View Cortone Acetate Review and Cortone Acetate Label ), NITRODERM (View Nitroderm Review and Nitroderm Label ), CORDARONE (View Cordarone Review and Cordarone Label ), COUMADIN (View Coumadin Review and Coumadin Label ), DILATREND (View Dilatrend Review and Dilatrend Label ).

6744461-1 | Abdominal Pain, Alanine Aminotransferase Increased, Fatigue, Gamma-glutamyltransferase Increased, Malaise, Vomiting
Patient was taking Mitotane (View Usage). Patient had the following side effects: abdominal pain (What is abdominal pain?), alanine aminotransferase increased, fatigue, gamma-glutamyltransferase increased, malaise, vomiting on May 25, 2010 from FRANCE Additional patient health information: Male patient , 67 years of age, was diagnosed with adrenocortical carcinoma and. Mitotane dosage: Dose Reduced 2.5mg To 1.5mg Daily.. During the same period patient was treated with CORTONE ACETATE (Frequency=1.25 Dosage Forms(1/2+1/2+1/4)) (View Cortone Acetate Review and Cortone Acetate Label ), NITRODERM (View Nitroderm Review and Nitroderm Label ), CORDARONE (View Cordarone Review and Cordarone Label ), COUMADIN (View Coumadin Review and Coumadin Label ), DILATREND (View Dilatrend Review and Dilatrend Label ).

6527202-2 | Abasia, Asthenia, Neurotoxicity
Adverse event was reported on Dec 29, 2009 by a Male patient taking Mitotane (View Usage) (Dosage: ) was diagnosed with adrenal carcinoma and. Location: FRANCE , 69 years of age, After Mitotane was administered, patient had the following side effects: abasia, asthenia, neurotoxicity. During the same period patient was treated with ASPIRIN (View Aspirin Review and Aspirin Label ), HYDROCORTISONE (View Hydrocortisone Review and Hydrocortisone Label ), OMEPRAZOLE (View Omeprazole Review and Omeprazole Label ), PARACETAMOL (View Paracetamol Review and Paracetamol Label ), SIMVASTATIN (View Simvastatin Review and Simvastatin Label ). Patient was hospitalized and became disabled.

6526525-0 | Abdominal Pain, Alanine Aminotransferase Increased, Fatigue, Gamma-glutamyltransferase Increased, Malaise, Vomiting
on Dec 29, 2009 Male patient from FRANCE , 67 years of age, was diagnosed with adrenocortical carcinoma and was treated with Mitotane (View Usage). Patient experienced the following unwanted or unexpected effects: abdominal pain (What is abdominal pain?), alanine aminotransferase increased, fatigue, gamma-glutamyltransferase increased, malaise, vomiting. Mitotane dosage: Dose Reduced 2.5mg To 1.5mg Daily.. During the same period patient was treated with CORTONE ACETATE (Frequency=1.25 Dosage Forms(1/2+1/2+1/4)) (View Cortone Acetate Review and Cortone Acetate Label ), NITRODERM (View Nitroderm Review and Nitroderm Label ), CORDARONE (View Cordarone Review and Cordarone Label ), COUMADIN (View Coumadin Review and Coumadin Label ), DILATREND (View Dilatrend Review and Dilatrend Label ).


6515570-7 | Cholangitis Sclerosing, Hepatitis
on Dec 11, 2009 Female patient from UNITED KINGDOM , 62 years of age, was diagnosed with adrenal carcinoma and was treated with Mitotane (View Usage). Patient had the following side effects: cholangitis sclerosing, hepatitis (What is hepatitis?). Mitotane dosage: . During the same period patient was treated with STEROIDS (View Steroids Review and Steroids Label ). Patient was hospitalized and became disabled.

6415578-6 | Abdominal Pain, Alanine Aminotransferase Increased, Fatigue, Gamma-glutamyltransferase Increased, Malaise, Vomiting
Patient was taking Mitotane (View Usage). After Mitotane was administered, patient had the following side effects: abdominal pain (What is abdominal pain?), alanine aminotransferase increased, fatigue, gamma-glutamyltransferase increased, malaise, vomiting on Oct 19, 2009 from FRANCE Additional patient health information: Male patient , 67 years of age, was diagnosed with adrenocortical carcinoma and. Mitotane dosage: Reduced To 1.5gm. During the same period patient was treated with CORTONE ACETATE (1.25 Df= (1/2+1/2+1/4)) (View Cortone Acetate Review and Cortone Acetate Label ), NITRODERM (View Nitroderm Review and Nitroderm Label ), CORDARONE (View Cordarone Review and Cordarone Label ), COUMADIN (View Coumadin Review and Coumadin Label ), DILATREND (View Dilatrend Review and Dilatrend Label ).

6398149-X | Cholangitis Sclerosing, Hepatitis
Adverse event was reported on Oct 01, 2009 by a Female patient taking Mitotane (View Usage) (Dosage: ) was diagnosed with adrenal carcinoma and. Location: FRANCE , 62 years of age, Patient experienced the following unwanted or unexpected effects: cholangitis sclerosing, hepatitis (What is hepatitis?). During the same period patient was treated with STEROIDS (View Steroids Review and Steroids Label ). Patient was hospitalized.

6149153-8 | Encephalopathy
on Mar 30, 2009 Male patient from FRANCE , child 4 years of age, weighting 52.91 lb, was diagnosed with adrenocortical carcinoma, precocious puberty, adrenal insufficiency and was treated with Mitotane (View Usage). Patient had the following side effects: encephalopathy. Mitotane dosage: Dose Increased Gradually By 0.5g/d Up To 5g/d. During the same period patient was treated with LEUPRORELIN (View Leuprorelin Review and Leuprorelin Label ), HYDROCORTISONE (View Hydrocortisone Review and Hydrocortisone Label ).

5771680-3 | Abasia, Asthenia, Neurotoxicity
on Jun 02, 2008 Male patient from FRANCE , 69 years of age, was diagnosed with adrenal carcinoma and was treated with Mitotane (View Usage). After Mitotane was administered, patient had the following side effects: abasia, asthenia, neurotoxicity. Mitotane dosage: . During the same period patient was treated with ASPIRIN (View Aspirin Review and Aspirin Label ), HYDROCORTISONE (View Hydrocortisone Review and Hydrocortisone Label ), OMEPRAZOLE (View Omeprazole Review and Omeprazole Label ), ACETAMINOPHEN (View Acetaminophen Review and Acetaminophen Label ), SIMVASTATIN (View Simvastatin Review and Simvastatin Label ). Patient was hospitalized and became disabled.

5708996-2 | Adrenal Carcinoma, Blister, Disease Progression, Erythema Multiforme, Lip Erosion, Wound Secretion
Patient was taking Mitotane (View Usage). Patient experienced the following unwanted or unexpected effects: adrenal carcinoma, blister, disease progression, erythema multiforme, lip erosion, wound secretion on Apr 16, 2008 from UNITED STATES Additional patient health information: Female patient , 65 years of age, weighting 198.4 lb, was diagnosed with adrenal carcinoma and. Mitotane dosage: 2000mg Qid Po. During the same period patient was treated with DECADRON (View Decadron Review and Decadron Label ), SENOKET (View Senoket Review and Senoket Label ), ENOXAPARIN SODIUM (View Enoxaparin Sodium Review and Enoxaparin Sodium Label ), ZETIA (View Zetia Review and Zetia Label ), FENTANYL CITRATE (View Fentanyl Citrate Review and Fentanyl Citrate Label ), LASIX (View Lasix Review and Lasix Label ), ATARAX (View Atarax Review and Atarax Label ), LISINOPRIL (View Lisinopril Review and Lisinopril Label ). Patient was hospitalized.