Morphine Side Effects
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Morphine Safety Reports reported to FDA
Total Morphine reports: 473.Morphine FDA safety alerts: 2002 2003 2005 2007 .
Reported deaths: 162 Reported hospitalizations: 144.
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Reported Morphine Side Effects: overdose, cardio-respiratory arrest, death, loss of consciousness, respiratory depression, nausea, somnolence, accidental overdose, confusional state, depressed level of consciousness, vomiting.
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Showing 1-50 of 473 Next >
Morphine Side Effects Report #5226759-1Physician from UNITED STATES reported MORPHINE problem on Nov 30, 2006. Female patient, 19 years of age, was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: cardio-respiratory arrest. MORPHINE dosage: unknown. During the same period patient was treated with ALPRAZOLAM. Patient died.
Morphine Side Effects Report #5226760-8
MORPHINE problem was reported by a Physician from UNITED STATES on Nov 30, 2006. Female patient, 51 years of age, was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: cardio-respiratory arrest, completed suicide. MORPHINE dosage: unknown. During the same period patient was treated with DIAZEPAM, TRICYCLIC ANTIDEPRESSANTS. Patient died.
Morphine Side Effects Report #5227139-5
Physician from GERMANY reported MORPHINE problem on Jan 15, 2007. Female patient, 26 years of age, weighting 112.4 lb, was diagnosed with pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: cardiac arrest, device failure, hypoxic encephalopathy, inadequate analgesia, loss of consciousness, respiratory depression. MORPHINE dosage: 5 MG, SINGLE, INTRAVENOUS; SEE IMAGE. During the same period patient was treated with FLUNITRAZEPAM, ATROPINE, THIOPENTAL, SUXAMETHONIUM CHLORIDE, PANCURONIUM BROMIDE, SEVOFLURANE, FENTANYL. Patient died.
Morphine Side Effects Report #5228306-7
MORPHINE problem was reported by a Pharmacist from UNITED STATES on Jan 31, 2007. Female patient, 57 years of age, was diagnosed with migraine and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: loss of consciousness, respiratory rate decreased. MORPHINE dosage: 4 MG PER HOUR IV. During the same period patient was treated with VERAPAMIL, VALIUM, PHENERGAN, LIDOCAINE, TOPIRATE, REGLAN, COMPAZINE. Patient recovered.
Morphine Side Effects Report #5228535-2
Consumer or non-health professional from UNITED STATES reported MORPHINE problem on Jan 30, 2007. Male patient, 74 years of age, weighting 215.6 lb, was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: delirium. MORPHINE dosage: unknown. Patient recovered.
Morphine Side Effects Report #5228542-X
MORPHINE problem was reported by a Consumer or non-health professional from UNITED STATES on Jan 31, 2007. Male patient, 58 years of age, weighting 229.5 lb, was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: rash. MORPHINE dosage: unknown. Patient recovered.
Morphine Side Effects Report #5229163-5
Consumer or non-health professional from reported MORPHINE problem on Jan 31, 2007. Male patient, 78 years of age, weighting 185.2 lb, was diagnosed with allergy test and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: contusion, dizziness, fall, inflammation, pyrexia. MORPHINE dosage: unknown. Patient was hospitalized. Patient recovered.
Morphine Side Effects Report #5229164-7
MORPHINE problem was reported by a Consumer or non-health professional from on Feb 01, 2007. Female patient, 70 years of age, was diagnosed with procedural pain, hypertension, diabetes mellitus non-insulin-dependent and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: bradycardia, haemoglobin decreased, hypercapnia, hypokalaemia, hypomagnesaemia, hypophosphataemia, hypotension, personality change, unresponsive to stimuli. MORPHINE dosage: 0.2 MG/ML, INFUSION OF 2 ML/H. During the same period patient was treated with BUPIVACAINE, CHLORTHALIDONE, METOPROLOL TARTRATE, ENALAPRIL MALEATE, INSULIN. Patient was hospitalized and became disabled. Patient recovered.
Morphine Side Effects Report #5232652-0
Pharmacist from UNITED STATES reported MORPHINE problem on Feb 06, 2007. Male patient, 59 years of age, weighting 107.0 lb, was diagnosed with pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: abdominal distension, abdominal pain upper, abdominal rigidity, flatulence, ileus paralytic, intestinal obstruction, oral intake reduced. MORPHINE dosage: 60 MG EVERY 12 HOURS PO. During the same period patient was treated with OXYCODONE, FERROUS SULPHATE, METHOCARBAMOL, POLYETHYLENE GLYCOL, CAPSAICIN, CALCIUM CARBONATE, FLUNISOLIDE, PANCRELIPASE. Patient was hospitalized. Patient recovered.
Morphine Side Effects Report #5232653-2
MORPHINE problem was reported by a Pharmacist from UNITED STATES on Feb 06, 2007. Male patient, weighting 150.0 lb, was diagnosed with pain, parkinson's disease and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: fall, mental status changes. MORPHINE dosage: 15MG DAILY TO BID PO. During the same period patient was treated with CARBIDOPA, WARFARIN, SOTALOL HYDROCHLORIDE, LISINOPRIL, CARBIDOPA AND LEVODOPA, HYDROCODONE, CALCITONIN, SENNA. Patient was hospitalized. Patient recovered.
Morphine Side Effects Report #5237886-7
Consumer or non-health professional from reported MORPHINE problem on Feb 09, 2007. Female patient, 81 years of age, weighting 143.3 lb, was diagnosed with spinal anaesthesia and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: dyspnoea, lethargy, loss of consciousness, miosis, nausea, overdose, unresponsive to stimuli, vomiting. MORPHINE dosage: unknown. During the same period patient was treated with DIAZEPAM, BUPIVACAINE, SUFENTANIL CITRATE. Patient was hospitalized. Patient recovered.
Morphine Side Effects Report #5237887-9
MORPHINE problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 13, 2007. Female patient was diagnosed with pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: dyspnoea. MORPHINE dosage: 15 MG QD X 2 DAYS. Patient died on 01/10/2007.
Morphine Side Effects Report #5241232-2
Pharmacist from UNITED STATES reported MORPHINE problem on Feb 12, 2007. Male patient, 60 years of age, was diagnosed with procedural pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: hypotension. MORPHINE dosage: unknown. During the same period patient was treated with ACETAMINOPHEN, ALBUTEROL, AMYLASE, CALCIUM CARBONATE, CEFAZOLIN, CHLORDIAZEPOXIDE, DILTIAZEM, DOCUSATE. Patient was hospitalized. Patient recovered.
Morphine Side Effects Report #5241552-1
MORPHINE problem was reported by a Pharmacist from UNITED STATES on Feb 12, 2007. Male patient, 92 years of age, weighting 159.0 lb, was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: mental status changes, respiratory distress. MORPHINE dosage: unknown. Patient was hospitalized. Patient recovered.
Morphine Side Effects Report #5241939-7
Consumer or non-health professional from reported MORPHINE problem on Feb 14, 2007. Female patient, 31 years of age, weighting 121.3 lb, was diagnosed with cancer pain, colon cancer, metastasis and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: neoplasm progression, sedation. MORPHINE dosage: BASAL INFUSION OF 0,36 MG/KG/H, 10 MG BOLUS EVERY 5 MIN, MAXIMUM 12 DOSES PER H, TITRATION TO 0,91 M. During the same period patient was treated with OXYCODONE, GABAPENTIN, KETAMINE, MITOMYCIN, FLUOROURACIL. Patient died.
Morphine Side Effects Report #5242397-9
MORPHINE problem was reported by a Pharmacist from UNITED STATES on Feb 16, 2007. Male patient, 78 years of age, was diagnosed with pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: constipation. MORPHINE dosage: 20 MG Q3H PRN. During the same period patient was treated with SENNOSIDES, NORTRIPTYLINE, ATENOLOL, PROMETHAZINE. Patient was hospitalized. Patient recovered.
Morphine Side Effects Report #5242446-8
Consumer or non-health professional from UNITED STATES reported MORPHINE problem on Feb 03, 2007. Male patient, 47 years of age, was diagnosed with back pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: granuloma, intraspinal abscess, medical device complication, paraplegia, spinal cord compression, streptococcal abscess. MORPHINE dosage: 32 MG QD IT. Patient recovered.
Morphine Side Effects Report #5243092-2
MORPHINE problem was reported by a Consumer or non-health professional from on Feb 19, 2007. Female patient, 59 years of age, was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: nausea, nystagmus, vision blurred, vomiting. MORPHINE dosage: unknown. During the same period patient was treated with MIDAZOLAM, BUPIVACAINE. Patient recovered.
Morphine Side Effects Report #5245645-4
Consumer or non-health professional from reported MORPHINE problem on Feb 19, 2007. Male patient, 47 years of age, was diagnosed with back pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: infusion site mass, intraspinal abscess, streptococcal infection. MORPHINE dosage: REQUIRED A LARGE INCREASE IN DAILY DOSING (BEFORE, THE DAILY WAS 32 MG). Patient was hospitalized. Patient recovered.
Morphine Side Effects Report #5246551-1
MORPHINE problem was reported by a Pharmacist from UNITED STATES on Feb 26, 2007. Male patient, 52 years of age, weighting 361.3 lb, was diagnosed with postoperative analgesia and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: hypercapnia, hypoxia, unresponsive to stimuli. MORPHINE dosage: unknown. During the same period patient was treated with PERCOCET, WELLBUTRIN, DUOUEB, GLUCOTROL, SYNTHROID, ADVAIR DISKUS, LYRICA, NICOTINE. Patient was hospitalized. Patient recovered.
Morphine Side Effects Report #5252987-5
Consumer or non-health professional from SWITZERLAND reported MORPHINE problem on Feb 09, 2007. Female patient, 59 years of age, was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: nausea, nystagmus, vision blurred, vomiting. MORPHINE dosage: 0.6 MG ONCE IT. During the same period patient was treated with MIDAZOLAM, BUPIVACAINE. Patient recovered.
Morphine Side Effects Report #5253227-3
MORPHINE problem was reported by a Health Professional from UNITED STATES on Feb 23, 2007. Male patient was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: abasia, activities of daily living impaired, drooling. MORPHINE dosage: 15 MG, BID. Patient recovered.
Morphine Side Effects Report #5256247-8
Consumer or non-health professional from reported MORPHINE problem on Feb 23, 2007. Male patient was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: depressed level of consciousness, mobility decreased. MORPHINE dosage: unknown. Patient recovered.
Morphine Side Effects Report #5257158-4
MORPHINE problem was reported by a Health Professional from UNITED STATES on Feb 27, 2007. Male patient was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: abasia, activities of daily living impaired, drooling. MORPHINE dosage: 15 MG, BID. Patient recovered.
Morphine Side Effects Report #5261745-7
Health Professional from UNITED STATES reported MORPHINE problem on Sept 13, 2005. Female patient, 53 years of age, weighting 280.0 lb, was diagnosed with postoperative analgesia and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: overdose, respiratory depression. MORPHINE dosage: unknown. During the same period patient was treated with EFFEXOR, ALTACE, PANTOPRAZOLE, ATIVAN, NEURONTIN, FLEXERIL, INSULIN. Patient was hospitalized. Patient recovered.
Morphine Side Effects Report #5261748-2
MORPHINE problem was reported by a Consumer or non-health professional from UNITED STATES on Dec 13, 2005. Male patient, weighting 362.0 lb, was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: respiratory arrest. MORPHINE dosage: 2 MG, PCA DOSE 10 MIN LOCKOUT 1.5MG/HR. Patient recovered.
Morphine Side Effects Report #5261750-0
Health Professional from UNITED STATES reported MORPHINE problem on Dec 12, 2005. Male patient, 74 years of age, was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: depressed level of consciousness, overdose. MORPHINE dosage: unknown. Patient recovered.
Morphine Side Effects Report #5261752-4
MORPHINE problem was reported by a Consumer or non-health professional from UNITED STATES on Mar 06, 2006. Male patient, 76 years of age, was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: overdose, unresponsive to stimuli. MORPHINE dosage: 2 MG PCA DOSE AND 20MG 4 HR LIMIT, INTRAVENOUS. Patient recovered.
Morphine Side Effects Report #5261753-6
Health Professional from UNITED STATES reported MORPHINE problem on June 12, 2006. Female patient was diagnosed with postoperative care, spinal fusion surgery and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: respiratory arrest. MORPHINE dosage: 2 MG, 10 MIN LOCKOUT, INTRAVENOUS. During the same period patient was treated with MORPHINE SULPHATE, LACTATED RINGER. Patient recovered.
Morphine Side Effects Report #5261754-8
MORPHINE problem was reported by a Pharmacist from UNITED STATES on July 20, 2006. Female patient, 38 years of age, was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: depressed level of consciousness, overdose. MORPHINE dosage: 12 MG, 1 IN 1HR, INTRAVENOUS. During the same period patient was treated with IMITREX. Patient recovered.
Morphine Side Effects Report #5261755-X
Consumer or non-health professional from UNITED STATES reported MORPHINE problem on Aug 04, 2006. Female patient was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: depressed level of consciousness, overdose. MORPHINE dosage: unknown. Patient recovered.
Morphine Side Effects Report #5261756-1
MORPHINE problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 02, 2005. Female patient, child 8 years of age, weighting 55.12 lb, was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: respiratory arrest. MORPHINE dosage: unknown. During the same period patient was treated with DEPAKOTE, ANTIBIOTICS. Patient died on 10/25/2001.
Morphine Side Effects Report #5268231-9
Health Professional from UNITED STATES reported MORPHINE problem on Mar 02, 2007. Male patient, 47 years of age, was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: device related infection, diplegia, infusion site abscess, infusion site mass, spinal cord compression, streptococcal infection. MORPHINE dosage: 32 MG, 1 IN D, INTRATHECAL. Patient recovered.
Morphine Side Effects Report #5273523-3
MORPHINE problem was reported by a Health Professional from UNITED STATES on Mar 21, 2007. Male patient, 35 years of age, weighting 200.0 lb, was diagnosed with pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: pruritus. MORPHINE dosage: 2MG IV. Patient recovered.
Morphine Side Effects Report #5274212-1
Consumer or non-health professional from reported MORPHINE problem on Mar 16, 2007. Female patient, 77 years of age, was diagnosed with dyspnoea and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: acute pulmonary oedema, delusion of replacement. MORPHINE dosage: unknown. During the same period patient was treated with DIGOXIN, FUROSEMIDE, METOLAZONE, POTASSIUM ACETATE, SPIRONOLACTONE, WARFARIN, OXYGEN. Patient died.
Morphine Side Effects Report #5276118-0
MORPHINE problem was reported by a Health Professional from UNITED STATES on Mar 13, 2007. Male patient, 47 years of age, was diagnosed with back pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: injection site mass, injection site nodule, intraspinal abscess, streptococcal infection. MORPHINE dosage: unknown. Patient was hospitalized. Patient recovered.
Morphine Side Effects Report #5276203-3
Consumer or non-health professional from reported MORPHINE problem on Mar 23, 2007. Female patient, 78 years of age, was diagnosed with induction of anaesthesia, intubation and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: delayed recovery from anaesthesia, miosis, respiratory depression. MORPHINE dosage: unknown. During the same period patient was treated with FENTANYL, MIDAZOLAM, PROPOFOL, ROCURONIUM BROMIDE, SEVOFLURANE, CYCLIZINE, HARTMANN, SUCCINYLATED GELATIN. Patient recovered.
Morphine Side Effects Report #5280664-3
MORPHINE problem was reported by a Physician from UNITED STATES on Mar 20, 2007. Male patient, 55 years of age, was diagnosed with pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: granuloma. MORPHINE dosage: unknown. Patient recovered.
Morphine Side Effects Report #5280750-8
Physician from UNITED STATES reported MORPHINE problem on Mar 20, 2007. Male patient, 45 years of age, was diagnosed with back pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: granuloma. MORPHINE dosage: unknown. Patient recovered.
Morphine Side Effects Report #5282957-2
MORPHINE problem was reported by a Pharmacist from UNITED STATES on Mar 28, 2007. Male patient, 53 years of age, weighting 182.5 lb, was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: urticaria. MORPHINE dosage: unknown. During the same period patient was treated with DIATRIZOATE MEGLUMINE, CITALOPRAM HYDROBROMIDE, FOLIC ACID, THIAMINE, FAMCICLOVIR, FLUNISOLIDE. Patient recovered.
Morphine Side Effects Report #5282975-4
Pharmacist from UNITED STATES reported MORPHINE problem on Mar 28, 2007. Male patient, 53 years of age, weighting 254.0 lb, was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: pruritus, urticaria. MORPHINE dosage: unknown. Patient recovered.
Morphine Side Effects Report #5283743-X
MORPHINE problem was reported by a Consumer or non-health professional from UNITED STATES on Mar 20, 2007. Male patient, 58 years of age, was diagnosed with cancer pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: malignant neoplasm progression, neoplasm malignant. MORPHINE dosage: unknown. Patient died on 11/26/2006.
Morphine Side Effects Report #5288009-X
Consumer or non-health professional from reported MORPHINE problem on Mar 26, 2007. Male patient, 64 years of age, was diagnosed with cancer pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: hallucination, unresponsive to stimuli. MORPHINE dosage: 1.5 ML/HR. During the same period patient was treated with METHOTREXAT. Patient was hospitalized. Patient recovered.
Morphine Side Effects Report #5289333-7
MORPHINE problem was reported by a Pharmacist from UNITED STATES on Apr 04, 2007. Male patient, 49 years of age, was diagnosed with pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: dyspnoea, respiratory depression. MORPHINE dosage: 200MG Q12H PO. Patient recovered.
Morphine Side Effects Report #5289368-4
Pharmacist from UNITED STATES reported MORPHINE problem on Apr 04, 2007. Male patient, 67 years of age, weighting 196.2 lb, was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: injection site erythema, pain in extremity. MORPHINE dosage: unknown. During the same period patient was treated with NITROGLYCERIN OINT, PROTONIX, ATENOLOL, REGLAN, LORAZEPAM, ACETAMINOPHEN AND HYDROCODONE BITARTRATE, ONDANSETRON. Patient recovered.
Morphine Side Effects Report #5290626-8
MORPHINE problem was reported by a Pharmacist from UNITED STATES on Apr 05, 2007. Male patient, 56 years of age, was diagnosed with pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: depressed level of consciousness, hypotension, mental status changes, tachycardia. MORPHINE dosage: 7 MG IV OTU. Patient recovered.
Morphine Side Effects Report #5291085-1
Health Professional from UNITED STATES reported MORPHINE problem on Apr 04, 2007. Female patient, 27 years of age, was diagnosed with neuralgia and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: irritability, overdose, pain, renal impairment. MORPHINE dosage: 30 MG, QID. Patient was hospitalized. Patient recovered.
Morphine Side Effects Report #5293247-6
MORPHINE problem was reported by a Consumer or non-health professional from on Mar 27, 2007. Male patient, 50 years of age, was diagnosed with back pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: delusion, encephalopathy, hallucination, hypertensive crisis. MORPHINE dosage: unknown. Patient recovered.
Morphine Side Effects Report #5293976-4
Physician from UNITED STATES reported MORPHINE problem on Mar 21, 2007. Male patient, 52 years of age, weighting 215.0 lb, was diagnosed with procedural pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: arthralgia, dyskinesia, hallucination, pain in extremity. MORPHINE dosage: 30 MG, Q12H, ORAL. During the same period patient was treated with TRAMADOL, TRIAMTERENE AND HYDROCHLOROTHIAZID, PAXIL, NEURONTIN, DILAUDID, VALIUM. Patient was hospitalized. Patient recovered.
Morphine Side Effects Report #5294393-3
MORPHINE problem was reported by a Pharmacist from UNITED STATES on Apr 09, 2007. Male patient, 77 years of age, weighting 145.9 lb, was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: nausea, vomiting. MORPHINE dosage: unknown. Patient recovered.
Showing 1-50 of 473 Next >
Drug Information: Morphine Oral
URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682133.html
(mor' feen)IMPORTANT WARNING:
| Morphine is available as long acting capsules or tablets. These capsules or tablets contain enough morphine to relieve pain for 12 or 24 hours and are designed to release the medication slowly over that period of time. It is very important not to split, chew, or crush these tablets or capsules and not to dissolve the beads contained in the capsules in any liquid before you swallow them. This would release all of the medication into your body at once and could cause serious health problems or death.If you are taking Oramorph® SR or MS Contin® brand long-acting tablets or Avinza® or Kadian® brand long-acting capsules, you should swallow the tablets or capsules whole. If you are unable to swallow the capsules, you can carefully open a capsule, sprinkle all of the beads that it contains on a spoonful of cold or room temperature applesauce, and swallow the entire mixture immediately without chewing or crushing the beads. Then rinse your mouth with a little water and swallow the water to be sure that you have swallowed all the medication. Do not save mixtures of medication and applesauce for later.If you are taking Avinza® brand long-acting capsules, you should not drink any drinks that contain alcohol or take any prescription or non-prescription medications that contain alcohol. Ask your doctor or pharmacist or check the list of ingredients if you do not know if a medication contains alcohol. Alcohol may cause the morphine in Avinza® brand long-acting capsules to be released in your body too quickly, causing serious health problems or death. |
Why is this medication prescribed?
Morphine is used to relieve moderate to severe pain. Morphine long-acting tablets and capsules are only used by patients who are expected to need medication to relieve moderate to severe pain around-the-clock for longer than a few days. Morphine is in a class of medications called opiate (narcotic) analgesics. It works by changing the way the body senses pain.
How should this medicine be used?
Morphine comes as a tablet, a solution (liquid), a controlled- or extended-release (long-acting) tablet, and a controlled- or sustained-release (long-acting) capsule all to take by mouth. The regular tablet and liquid usually are taken every 4 hours. The long acting tablet is usually taken every 8-12 hours. Kadian ®brand long-acting capsules are usually taken with or without food every 12 hours or every 24 hours. Avinza® brand long acting capsules are usually taken once a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.
If you are taking morphine solution, use the spoon or dropper that comes with the medication to measure your dose. Be sure that you know how many milliliters of the solution you should take. Ask your pharmacist if you have any questions about how much medication you should take or how to use the spoon or dropper.
If you are taking Kadian® brand long-acting capsules and you have a gastrostomy tube (surgically inserted feeding tube), ask your doctor or pharmacist how to administer the medication through your tube.
Your doctor may start you on a low dose of morphine and gradually increase your dose until your pain is controlled. Your doctor may adjust your dose at any time during your treatment if your pain is not controlled. If you feel that your pain is not controlled, call your doctor. Do not change the dose of your medication without talking to your doctor.
Morphine can be habit-forming. Take morphine exactly as directed. Do not take a larger dose, take it more often, or take it for a longer period of time or in a different way than prescribed by your doctor.
Do not stop taking morphine without talking to your doctor. Your doctor may decrease your dose gradually. If you suddenly stop taking morphine, you may experience withdrawal symptoms such as anxiety; sweating; difficulty falling asleep or staying asleep; chills; shaking of a part of your body that you cannot control; upset stomach; diarrhea; runny nose, sneezing or coughing; hair on your skin standing on end; or hallucinating (seeing things or hearing voices that do not exist).
Other uses for this medicine
This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking morphine,
- tell your doctor and pharmacist if you are allergic to morphine, any other medications, or any of the inactive ingredients in the type of morphine tablets, capsules, or liquid you plan to take. Ask your pharmacist for a list of the inactive ingredients.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin);antidepressants such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); antihistamines (found in cold and allergy medications); beta blockers such as atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), and propranolol (Inderal); buprenorphine (Subutex, in Suboxone);butorphanol (Stadol); cimetidine (Tagamet); diuretics ('water pills'); medications for anxiety, mental illness, pain, seizures, or upset stomach; muscle relaxants; nalbuphine (Nubain); pentazocine (Talwin, in Talacen); sedatives; sleeping pills; and tranquilizers. Also tell your doctor if you are taking any of the following medications or if you have stopped taking them within the past 2 weeks: monoamine oxidase (MAO) inhibitors, including isocarboxazid (Marplan), phenelzine (Nardil), procarbazine (Matulane), selegiline (Eldepryl), and tranylcypromine (Parnate). Your doctor may need to change the doses of your medications or monitor you more carefully for side effects.
- tell your doctor if you drink or have ever drunk large amounts of alcoholand if you have ever had major surgery. Also tell your doctor if you have or have ever had a head injury; a brain tumor; seizures; mental illness; difficulty swallowing; lung disease such as asthma, chronic obstructive pulmonary disease (COPD; a group of diseases that cause gradual loss of lung function), or other breathing problems; prostatic hypertrophy (enlargement of a male reproductive gland); urinary problems; low blood pressure; irregular heartbeat; Addison's disease (condition in which the body does not make enough of certain natural substances); or liver, kidney, pancreatic, intestinal, or gallbladder disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking morphine, call your doctor.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking morphine.
- you should know that this medication may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.
- talk to your doctor about the safe use of alcohol while you are taking this medication.
- you should know that morphine may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.
What special dietary instructions should I follow?
Drink plenty of fluids while you are taking this medication.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
Morphine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- dizziness
- lightheadedness
- drowsiness
- upset stomach
- vomiting
- constipation
- diarrhea
- loss of appetite
- weight loss
- changes in ability to taste food
- dry mouth
- sweating
- weakness
- headache
- agitation
- nervousness
- mood changes
- confusion
- difficulty falling asleep or staying asleep
- stiff muscles
- shaking of a part of your body that you cannot control
- double vision
- red eyes
- small pupils (black circles in the middle of the eyes
- eye movements that you cannot control
- chills
- flu symptoms
- decreased sexual desire or ability
- difficulty urinating or pain when urinating
Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:
- slow, shallow, or irregular breathing
- blue or purple color to the skin
- fast or slow heartbeat
- seizures
- hallucinations (seeing things or hearing voices that do not exist)
- blurred vision
- fainting
- hives
- rash
- itching
- tightness in the throat
- difficulty swallowing
- swelling of the arms, hands, feet, ankles, or lower legs
Morphine may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].
What storage conditions are needed for this medicine?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
Store morphine in a safe place so that no one else can take it accidentally or on purpose. Keep track of how many tablets or capsules or how much liquid is left so you will know if any medication is missing.
In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Symptoms of overdose may include:
- slow, shallow, or irregular breathing
- sleepiness
- loss of consciousness
- limp muscles
- cold, clammy skin
- small pupils
- slow heartbeat
- blurred vision
- upset stomach
- fainting
What other information should I know?
Keep all appointments with your doctor.
Do not let anyone else take your medication. This prescription is not refillable. If you are taking morphine to control your pain on a long term basis, be sure to schedule appointments with your doctor so that you do not run out of medication. If you are taking morphine on a short term basis, call your doctor if you continue to experience pain after you finish the medication.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
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