NILOTINIB Side Effects

6917440-9 | Acute Myocardial Infarction, Chest Discomfort, Tachycardia, Troponin Increased
on Jul 26, 2010 Female patient from UNITED STATES , weighting 139.6 lb, was diagnosed with chronic myeloid leukaemia and was treated with Nilotinib (View Usage). Patient experienced the following unwanted or unexpected effects: acute myocardial infarction, chest discomfort, tachycardia, troponin increased. Nilotinib dosage: 800 Mg. Patient was hospitalized.

6800948-4 | Angina Pectoris, Anxiety, Aortic Arteriosclerosis, Arteriosclerosis Coronary Artery, Asthenia, Blood Pressure Diastolic Abnormal, Bronchopneumonia, Cardiac Arrest, Cardiac Hypertrophy
Patient was taking Nilotinib (View Usage). Patient had the following side effects: angina pectoris, anxiety (What is anxiety?), aortic arteriosclerosis, arteriosclerosis coronary artery, asthenia, blood pressure diastolic abnormal, bronchopneumonia, cardiac arrest (What is cardiac arrest?), cardiac hypertrophy on Jun 23, 2010 from SWITZERLAND Additional patient health information: Male patient , 60 years of age, was diagnosed with chronic myeloid leukaemia and. Nilotinib dosage: 400 Mg, Bid. During the same period patient was treated with ESCITALOPRAM (View Escitalopram Review and Escitalopram Label ), TORASEMIDE (View Torasemide Review and Torasemide Label ). Patient was hospitalized.

6729892-8 | Candidiasis, Febrile Neutropenia, Furuncle, Oedema Genital, Pain, Pyrexia
Adverse event was reported on May 04, 2010 by a Female patient taking Nilotinib (View Usage) (Dosage: 800 Mg, Unk) was diagnosed with chronic myeloid leukaemia and. Location: BRAZIL , weighting 126.3 lb, After Nilotinib was administered, patient had the following side effects: candidiasis, febrile neutropenia, furuncle, oedema genital, pain (What is pain?), pyrexia. During the same period patient was treated with CLINDAMYCIN (600 Mg, Tid) (View Clindamycin Review and Clindamycin Label ), FLUCONAZOLE (200 Mg, Qd) (View Fluconazole Review and Fluconazole Label ), NYSTATIN (Unk) (View Nystatin Review and Nystatin Label ). Patient was hospitalized.

6728091-3 | Electrocardiogram Qt Prolonged
on May 11, 2010 Male patient from UNITED ARAB EMIRATES , weighting 165.3 lb, was diagnosed with chronic myeloid leukaemia and was treated with Nilotinib (View Usage). Patient experienced the following unwanted or unexpected effects: electrocardiogram qt prolonged. Nilotinib dosage: 400 Mg, Bid.


6706618-5 | Electrocardiogram Qt Prolonged, Palpitations, Supraventricular Tachycardia
on Apr 30, 2010 Female patient from UNITED STATES , 80 years of age, weighting 172.0 lb, was diagnosed with chronic myeloid leukaemia and was treated with Nilotinib (View Usage). Patient had the following side effects: electrocardiogram qt prolonged, palpitations, supraventricular tachycardia. Nilotinib dosage: 400 Mg Once Daily Po. Patient was hospitalized.

6647070-8 | Acute Graft Versus Host Disease In Skin, Blast Crisis In Myelogenous Leukaemia, Blood Creatinine Increased, Malignant Neoplasm Progression, Oedema, Pancytopenia, Pleural Effusion, Pneumonia
Patient was taking Nilotinib (View Usage). After Nilotinib was administered, patient had the following side effects: acute graft versus host disease in skin, blast crisis in myelogenous leukaemia, blood creatinine increased, malignant neoplasm progression, oedema, pancytopenia, pleural effusion, pneumonia (What is pneumonia?) on Mar 10, 2010 from JAPAN Additional patient health information: Male patient , 50 years of age, was diagnosed with chronic myeloid leukaemia, prophylaxis and. Nilotinib dosage: 400 Mg, Bid. During the same period patient was treated with DASATINIB (100 Mg Daily) (View Dasatinib Review and Dasatinib Label ), DAUNORUBICIN HCL (50 Mg/m2 For 5 Days) (View Daunorubicin Hcl Review and Daunorubicin Hcl Label ), CYTOSINE ARABINOSIDE (100 Mg/m2 For 7 Days) (View Cytosine Arabinoside Review and Cytosine Arabinoside Label ), FLUDARABINE PHOSPHATE (30 Mg/m2) (View Fludarabine Phosphate Review and Fludarabine Phosphate Label ), TACROLIMUS (View Tacrolimus Review and Tacrolimus Label ), DALTEPARIN (View Dalteparin Review and Dalteparin Label ), URSODEOXYCHOLIC ACID (View Ursodeoxycholic Acid Review and Ursodeoxycholic Acid Label ), PREDNISOLONE (View Prednisolone Review and Prednisolone Label ). Patient was hospitalized.

6634008-2 | Blast Crisis In Myelogenous Leukaemia, Pancytopenia, Pneumonia, Subcutaneous Abscess, White Blood Cell Count Increased
Adverse event was reported on Mar 04, 2010 by a Male patient taking Nilotinib (View Usage) (Dosage: Unk) was diagnosed with chronic myeloid leukaemia, white blood cell count increased, blast crisis in myelogenous leukaemia, prophylaxis against graft versus host disease and. Location: JAPAN , 50 years of age, Patient experienced the following unwanted or unexpected effects: blast crisis in myelogenous leukaemia, pancytopenia, pneumonia (What is pneumonia?), subcutaneous abscess, white blood cell count increased. During the same period patient was treated with DAUNORUBICIN HCL (50 Mg/m2) (View Daunorubicin Hcl Review and Daunorubicin Hcl Label ), CYTOSINE ARABINOSIDE (100 Mg/m2) (View Cytosine Arabinoside Review and Cytosine Arabinoside Label ), DASATINIB (100 Mg Daily) (View Dasatinib Review and Dasatinib Label ), FLUDARABINE (30 Mg/m2 Per Day) (View Fludarabine Review and Fludarabine Label ), MELPHALAN (40 Mg/m2 Per Day) (View Melphalan Review and Melphalan Label ), TACROLIMUS (25-35 Ng/ml) (View Tacrolimus Review and Tacrolimus Label ), DALTEPARIN (View Dalteparin Review and Dalteparin Label ). Patient was hospitalized.

6593125-6 | Bronchitis, Candidiasis, Gastritis, Pseudomonas Infection
on Feb 08, 2010 Female patient from ITALY , 36 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with Nilotinib (View Usage). Patient had the following side effects: bronchitis (What is bronchitis?), candidiasis, gastritis, pseudomonas infection. Nilotinib dosage: 400 Mg, Bid.

6577156-8 | Blast Crisis In Myelogenous Leukaemia, Pancytopenia, Pneumonia, Subcutaneous Abscess, White Blood Cell Count Increased
on Jan 28, 2010 Male patient from JAPAN , 50 years of age, was diagnosed with chronic myeloid leukaemia, white blood cell count increased, blast crisis in myelogenous leukaemia, prophylaxis against graft versus host disease and was treated with Nilotinib (View Usage). After Nilotinib was administered, patient had the following side effects: blast crisis in myelogenous leukaemia, pancytopenia, pneumonia (What is pneumonia?), subcutaneous abscess, white blood cell count increased. Nilotinib dosage: Unk. During the same period patient was treated with DAUNORUBICIN HCL (50 Mg/m2) (View Daunorubicin Hcl Review and Daunorubicin Hcl Label ), CYTOSINE ARABINOSIDE (100 Mg/m2) (View Cytosine Arabinoside Review and Cytosine Arabinoside Label ), DASATINIB (100 Mg Daily) (View Dasatinib Review and Dasatinib Label ), FLUDARABINE (30 Mg/m2 Per Day) (View Fludarabine Review and Fludarabine Label ), MELPHALAN HYDROCHLORIDE (40 Mg/m2 Per Day) (View Melphalan Hydrochloride Review and Melphalan Hydrochloride Label ), TACROLIMUS (25-35 Ng/ml) (View Tacrolimus Review and Tacrolimus Label ), DALTEPARIN (View Dalteparin Review and Dalteparin Label ). Patient was hospitalized.

6436372-6 | Bronchitis, Candidiasis, Gastritis, Pseudomonas Infection
Patient was taking Nilotinib (View Usage). Patient experienced the following unwanted or unexpected effects: bronchitis (What is bronchitis?), candidiasis, gastritis, pseudomonas infection on Oct 29, 2009 from ITALY Additional patient health information: Female patient , 36 years of age, . Nilotinib dosage: 400 Mg, Bid.

6428493-9 | Adrenal Insufficiency, Dizziness, Headache
Adverse event was reported on Nov 04, 2009 by a Female patient taking Nilotinib (View Usage) (Dosage: 400 Mg Bid Po) was diagnosed with chronic myeloid leukaemia and. Location: UNITED STATES , 66 years of age, Patient had the following side effects: adrenal insufficiency, dizziness (What is dizziness?), headache (What is headache?). Patient was hospitalized.

6413156-6 | Cardiac Tamponade, Pericardial Effusion
on Oct 22, 2009 Male patient from UNITED STATES , 67 years of age, was treated with Nilotinib (View Usage). After Nilotinib was administered, patient had the following side effects: cardiac tamponade, pericardial effusion. Nilotinib dosage: 400 Mg Bid Po. Patient was hospitalized.

6382047-1 | Accidental Exposure
on Sep 16, 2009 Male patient from BRAZIL , 59 years of age, was treated with Nilotinib (View Usage). Patient experienced the following unwanted or unexpected effects: accidental exposure. Nilotinib dosage: 2 Capsules. During the same period patient was treated with DASATINIB (Unk) (View Dasatinib Review and Dasatinib Label ).

6368113-5 | Anaemia, Anuria, Apallic Syndrome, Arthralgia, Blast Cell Count Increased, Cardiac Massage, Cardio-respiratory Arrest, Chest Pain, Encephalopathy
Patient was taking Nilotinib (View Usage). Patient had the following side effects: anaemia, anuria, apallic syndrome, arthralgia, blast cell count increased, cardiac massage, cardio-respiratory arrest, chest pain (What is chest pain?), encephalopathy on Sep 14, 2009 from UNITED STATES Additional patient health information: Female patient , 66 years of age, was diagnosed with chronic myeloid leukaemia and. Nilotinib dosage: Unk. During the same period patient was treated with DASATINIB (50mg Daily) (View Dasatinib Review and Dasatinib Label ), NIZATIDINE (Unk) (View Nizatidine Review and Nizatidine Label ), ITRACONAZOLE (Unk) (View Itraconazole Review and Itraconazole Label ), SULFAMETHOXAZOLE AND TRIMETHOPRIM (Unk) (View Sulfamethoxazole And Trimethoprim Review and Sulfamethoxazole And Trimethoprim Label ), ZOLPIDEM TARTRATE (Unk) (View Zolpidem Tartrate Review and Zolpidem Tartrate Label ), ALLOPURINOL (Unk) (View Allopurinol Review and Allopurinol Label ). Patient was hospitalized.

6314060-4 | Blast Cell Count Increased, Neutrophil Count Decreased, Platelet Count Decreased, Pleural Effusion, Pneumonia
Adverse event was reported on Aug 10, 2009 by a Female patient taking Nilotinib (View Usage) (Dosage: Unk) was diagnosed with chronic myeloid leukaemia and. Location: UNITED STATES , 66 years of age, After Nilotinib was administered, patient had the following side effects: blast cell count increased, neutrophil count decreased, platelet count decreased, pleural effusion, pneumonia (What is pneumonia?). During the same period patient was treated with DASATINIB (50mg Daily) (View Dasatinib Review and Dasatinib Label ). Patient was hospitalized.

6271421-X | Apnoea, Cardiac Arrest, Disease Progression, Hypoventilation, Loss Of Consciousness, Miosis
on Jul 15, 2009 Male patient from UNITED STATES , weighting 189.0 lb, was diagnosed with gastrointestinal stromal tumour and was treated with Nilotinib (View Usage). Patient experienced the following unwanted or unexpected effects: apnoea, cardiac arrest (What is cardiac arrest?), disease progression, hypoventilation, loss of consciousness, miosis. Nilotinib dosage: 400mg Po Bid X 28 Days. During the same period patient was treated with DEXAMETHASONE (View Dexamethasone Review and Dexamethasone Label ), OXYCODONE (View Oxycodone Review and Oxycodone Label ), OXYCONTIN (View Oxycontin Review and Oxycontin Label ), HYDROMORPHONE HCL (View Hydromorphone Hcl Review and Hydromorphone Hcl Label ).

6253346-9 | Platelet Count Increased
on Jun 23, 2009 Male patient from UNITED STATES , 33 years of age, was diagnosed with chronic myeloid leukaemia and was treated with Nilotinib (View Usage). Patient had the following side effects: platelet count increased. Nilotinib dosage: . During the same period patient was treated with ANAGRELIDE HCL (View Anagrelide Hcl Review and Anagrelide Hcl Label ).

6248720-0 | Apnoea, Cardio-respiratory Arrest, Electrocardiogram St Segment Elevation, Hypoventilation, Loss Of Consciousness, Miosis, Ventricular Extrasystoles
Patient was taking Nilotinib (View Usage). After Nilotinib was administered, patient had the following side effects: apnoea, cardio-respiratory arrest, electrocardiogram st segment elevation, hypoventilation, loss of consciousness, miosis, ventricular extrasystoles on Jun 25, 2009 from UNITED STATES Additional patient health information: Female patient , weighting 189.0 lb, was diagnosed with gastrointestinal stromal tumour and. Nilotinib dosage: 400mg Po Bid X 28 Days. During the same period patient was treated with DEXAMETHASONE (View Dexamethasone Review and Dexamethasone Label ), OXYCODONE (View Oxycodone Review and Oxycodone Label ), OXYCONTIN (View Oxycontin Review and Oxycontin Label ), HYDROMORPHONE (View Hydromorphone Review and Hydromorphone Label ).

6125818-9 | Bronchitis, Candidiasis, Gastritis, Pseudomonas Infection
Adverse event was reported on Mar 12, 2009 by a Female patient taking Nilotinib (View Usage) (Dosage: 400 Mg, Bid) . Location: ITALY , 36 years of age, Patient experienced the following unwanted or unexpected effects: bronchitis (What is bronchitis?), candidiasis, gastritis, pseudomonas infection.

5867131-0 | Abdominal Pain, Diarrhoea, Electrocardiogram Qt Interval Abnormal, Electrocardiogram Qt Prolonged, Rash
on Aug 28, 2008 Male patient from UNITED STATES , weighting 194.9 lb, was diagnosed with b-cell type acute leukaemia and was treated with Nilotinib (View Usage). Patient had the following side effects: abdominal pain (What is abdominal pain?), diarrhoea, electrocardiogram qt interval abnormal, electrocardiogram qt prolonged, rash (What is rash?). Nilotinib dosage: 400mg Bid Po. During the same period patient was treated with VORICONAZOLE (View Voriconazole Review and Voriconazole Label ), LEVOFLOXACIN (View Levofloxacin Review and Levofloxacin Label ), NORVASC (View Norvasc Review and Norvasc Label ), MORPHINE (View Morphine Review and Morphine Label ), FILGRASTIM (View Filgrastim Review and Filgrastim Label ). Patient was hospitalized.

5776289-3 | Abdominal Pain, Diarrhoea, Electrocardiogram Qt Prolonged
on Jun 17, 2008 Male patient from UNITED STATES , weighting 194.9 lb, was diagnosed with acute lymphocytic leukaemia and was treated with Nilotinib (View Usage). After Nilotinib was administered, patient had the following side effects: abdominal pain (What is abdominal pain?), diarrhoea, electrocardiogram qt prolonged. Nilotinib dosage: 400mg Po Bid. During the same period patient was treated with VORICONAZOLE (View Voriconazole Review and Voriconazole Label ), NORVASC (View Norvasc Review and Norvasc Label ), LEVOFLOXACIN (View Levofloxacin Review and Levofloxacin Label ), MORPHINE (View Morphine Review and Morphine Label ), FILGRASTIM (View Filgrastim Review and Filgrastim Label ).

5718768-0 | Acute Lymphocytic Leukaemia, Malignant Neoplasm Progression
Patient was taking Nilotinib (View Usage). Patient experienced the following unwanted or unexpected effects: acute lymphocytic leukaemia, malignant neoplasm progression on Apr 21, 2008 from CANADA Additional patient health information: Male patient , 36 years of age, was diagnosed with acute biphenotypic leukaemia and. Nilotinib dosage: 400 Mg, Bid. During the same period patient was treated with MS CONTIN (15 Mg, Bid) (View Ms Contin Review and Ms Contin Label ).

5693750-0 | Acute Febrile Neutrophilic Dermatosis, Blister, Body Temperature Increased, C-reactive Protein Increased, Enterococcal Infection, Granuloma Skin, Haemorrhage Subepidermal, Inflammation, Monocyte Morphology Abnormal
Adverse event was reported on Mar 19, 2008 by a Female patient taking Nilotinib (View Usage) (Dosage: 400 Mg, Bid) was diagnosed with chronic myeloid leukaemia and. Location: GERMANY , 67 years of age, Patient had the following side effects: acute febrile neutrophilic dermatosis, blister, body temperature increased, c-reactive protein increased, enterococcal infection, granuloma skin, haemorrhage subepidermal, inflammation, monocyte morphology abnormal.

5510963-9 | Anaemia, Asthenia, Gastrointestinal Pain, Malignant Neoplasm Progression, Nausea
on Nov 01, 2007 Female patient from CANADA , 59 years of age, was diagnosed with gastrointestinal stromal tumour and was treated with Nilotinib (View Usage). After Nilotinib was administered, patient had the following side effects: anaemia, asthenia, gastrointestinal pain, malignant neoplasm progression, nausea (What is nausea?). Nilotinib dosage: 400 Mg, Bid. Patient was hospitalized.