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Community-reported Nitrofurantoin side effects:

fulminant hepatic failure and liver transplantation 2008-09-25 22:52:11

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Review Nitrofurantoin Safety Reports submitted to FDA

Total Nitrofurantoin reports: 38.
Nitrofurantoin FDA safety alerts: No.
Reported deaths: 7    Reported hospitalizations: 17.
Take Nitrofurantoin Side Effects Survey, Discuss Nitrofurantoin with others
FDA Reported Nitrofurantoin Side Effects: chills, asthenia, cough, dyspnoea exertional, dyspnoea, pyrexia, nausea, arthralgia, abdominal pain upper, oedema peripheral, fatigue.
Nitrofurantoin Usage.
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Nitrofurantoin Side Effects Report #5623824-1
Health Professional from UNITED STATES reported NITROFURANTOIN problem on Jan 28, 2008. Female patient was diagnosed with prophylaxis urinary tract infection and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: biliary cirrhosis, hepatotoxicity, pulmonary toxicity, transaminases increased. NITROFURANTOIN dosage: 50 MG; AT BEDTIME; ORAL. Patient was hospitalized. Patient died on 09/01/2007.

Nitrofurantoin Side Effects Report #5640757-5
NITROFURANTOIN problem was reported by a Health Professional from UNITED STATES on Feb 11, 2008. Female patient, 46 years of age, was diagnosed with neurogenic bladder, prophylaxis urinary tract infection and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: hepatic cirrhosis, hepatotoxicity, interstitial lung disease, lung disorder, pneumothorax, pulmonary fibrosis, pulmonary toxicity, respiratory disorder, respiratory distress. NITROFURANTOIN dosage: 50 MG; AT BEDTIME; ORAL, 100 MG; AT BEDTIME; ORAL. During the same period patient was treated with NORTRIPTYLINE, OXYBUTYNIN, ATENOLOL. Patient was hospitalized. Patient died on 11/04/2007.

Nitrofurantoin Side Effects Report #5643081-X
Pharmacist from UNITED STATES reported NITROFURANTOIN problem on Feb 27, 2008. Male patient, 60 years of age, weighting 172.0 lb, was diagnosed with urinary tract infection and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: pruritus, rash, urticaria. NITROFURANTOIN dosage: 100MG TID PO. Patient recovered.

Nitrofurantoin Side Effects Report #5648028-8
NITROFURANTOIN problem was reported by a Pharmacist from UNITED STATES on Feb 29, 2008. Male patient, 60 years of age, was diagnosed with urinary tract infection and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: pulmonary fibrosis. NITROFURANTOIN dosage: 100MG BID PO. Patient recovered.

Nitrofurantoin Side Effects Report #5579902-9
Health Professional from UNITED KINGDOM reported NITROFURANTOIN problem on Dec 31, 2007. Male patient, 24 years of age, weighting 165.3 lb, was diagnosed with urinary tract infection and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: angina pectoris, electrocardiogram abnormal. NITROFURANTOIN dosage: unknown. Patient was hospitalized. Patient recovered.

Nitrofurantoin Side Effects Report #5593502-6
NITROFURANTOIN problem was reported by a Health Professional from UNITED KINGDOM on Jan 14, 2008. Female patient, 22 years of age, was diagnosed with urinary tract infection and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: supraventricular tachyarrhythmia. NITROFURANTOIN dosage: unknown. Patient recovered.

Nitrofurantoin Side Effects Report #5603888-1
Consumer or non-health professional from UNITED STATES reported NITROFURANTOIN problem on Jan 23, 2008. Female patient, 18 years of age, weighting 215.0 lb, was diagnosed with urinary tract infection and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: anorexia, back pain, blood count abnormal, chest pain, cough, dehydration, diarrhoea, diarrhoea haemorrhagic. NITROFURANTOIN dosage: 100 MG 1 CAP 2X DAY. Patient was hospitalized. Patient recovered.

Nitrofurantoin Side Effects Report #5538323-5
NITROFURANTOIN problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 27, 2007. Female patient, 38 years of age, was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: anosmia, muscle spasms, myoclonus, paraesthesia, paraesthesia of genital female, peripheral sensory neuropathy, pollakiuria, sexual dysfunction, tremor. NITROFURANTOIN dosage: unknown. Patient recovered.

Nitrofurantoin Side Effects Report #5514047-5
Pharmacist from UNITED STATES reported NITROFURANTOIN problem on Nov 09, 2007. Female patient, 56 years of age, weighting 218.0 lb, was diagnosed with urinary tract infection and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: eosinophilia, infection, leukocytosis, lung neoplasm malignant, procedural site reaction. NITROFURANTOIN dosage: unknown. During the same period patient was treated with LEVOTHYROXINE, DIAZEPAM, CLONIDINE, GUANFACINE HYDROCHLORIDE, TRIAMTERENE AND HYDROCHLOROTHIAZIDE, LISINOPRIL, HUMULIN, DOCUSATE. Patient was hospitalized. Patient recovered.

Nitrofurantoin Side Effects Report #5518095-0
NITROFURANTOIN problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Oct 29, 2007. Female patient, 72 years of age, was diagnosed with urinary tract infection and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: lichen planus, vulval leukoplakia, vulvitis. NITROFURANTOIN dosage: 100 MG (100 MG,1 IN 1 D). Patient recovered.

Nitrofurantoin Side Effects Report #5523260-2
Health Professional from UNITED STATES reported NITROFURANTOIN problem on Nov 19, 2007. Female patient, weighting 125.0 lb, was diagnosed with cystitis and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: constipation. NITROFURANTOIN dosage: 100 MG 2X DAILY PO. Patient recovered.

Nitrofurantoin Side Effects Report #5527581-9
NITROFURANTOIN problem was reported by a Health Professional from NEW ZEALAND on Nov 21, 2007. Female patient was diagnosed with urinary tract infection and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: anxiety, cough, dyspnoea, hypoxia, interstitial lung disease, lung disorder, pneumonia, respiratory alkalosis. NITROFURANTOIN dosage: 50 MG, UNK. Patient was hospitalized. Patient recovered.

Nitrofurantoin Side Effects Report #5528187-8
Consumer or non-health professional from UNITED KINGDOM reported NITROFURANTOIN problem on Nov 09, 2007. Female patient, 84 years of age, was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: blood calcium decreased, confusional state, international normalised ratio increased, somnolence. NITROFURANTOIN dosage: unknown. During the same period patient was treated with WARFARIN, MICONAZOLE, ERGOCALCIFEROL. Patient recovered.

Nitrofurantoin Side Effects Report #5528554-2
NITROFURANTOIN problem was reported by a Health Professional from UNITED KINGDOM on Nov 09, 2007. Female patient, 84 years of age, was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: blood calcium decreased, confusional state, international normalised ratio increased, somnolence. NITROFURANTOIN dosage: unknown. During the same period patient was treated with MICONAZOLE, ERGOCALCIFEROL, WARFARIN, CALCIUM, COLECALCIFEROL, LAMOTRIGINE. Patient recovered.

Nitrofurantoin Side Effects Report #5531928-7
Consumer or non-health professional from UNITED STATES reported NITROFURANTOIN problem on Nov 28, 2007. Male patient, weighting 175.0 lb, was diagnosed with urinary tract infection and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: asthenia, chills, confusional state, constipation, dysstasia, headache, malaise, pyrexia. NITROFURANTOIN dosage: 100MG 2 CAPUSALS URETHRAL. Patient recovered.

Nitrofurantoin Side Effects Report #5532808-3
NITROFURANTOIN problem was reported by a Pharmacist from UNITED STATES on Nov 30, 2007. Female patient, 79 years of age, weighting 138.9 lb, was diagnosed with urinary tract infection and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: asthenia, blood creatinine increased, blood urea increased, chills, hepatitis, pain, pruritus. NITROFURANTOIN dosage: 100MG TWICE DAILY PO. During the same period patient was treated with ESOMEPRAZOLE, OXYBUTYNIN CHLORIDE, HYDROCHLOROTHIAZIDE, ASPIRIN, CHLORDIAZEPOXIDE, VALSARTAN, ATORVASTATIN, GLUCOSAMINE. Patient was hospitalized and became disabled. Patient recovered.

Nitrofurantoin Side Effects Report #5477746-X
Consumer or non-health professional from UNITED STATES reported NITROFURANTOIN problem on Oct 02, 2007. Female patient, 39 years of age, weighting 170.0 lb, was diagnosed with urinary tract infection and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: asthma, infection, influenza like illness, pneumonia, visual disturbance, vomiting. NITROFURANTOIN dosage: unknown. During the same period patient was treated with NITROFURANTOIN MACROCRYSTALLINE. Patient was hospitalized. Patient recovered.

Nitrofurantoin Side Effects Report #5485250-8
NITROFURANTOIN problem was reported by a Pharmacist from UNITED STATES on Oct 10, 2007. Female patient, 97 years of age, was diagnosed with escherichia urinary tract infection and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: compression fracture, confusional state, delirium, post procedural complication, pulmonary fibrosis. NITROFURANTOIN dosage: 100MG BID PO. During the same period patient was treated with FENTANYL, PERCOCET, TRAMADOL, MORPHINE, PREDNISONE, ASPIRIN, ZOLOFT. Patient was hospitalized. Patient recovered.

Nitrofurantoin Side Effects Report #5485286-7
Pharmacist from UNITED STATES reported NITROFURANTOIN problem on Oct 10, 2007. Female patient, 82 years of age, weighting 148.0 lb, was diagnosed with urinary tract infection and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: anaphylactic reaction, dyspnoea. NITROFURANTOIN dosage: 100 MG ONCE PO. Patient recovered.

Nitrofurantoin Side Effects Report #5488019-3
NITROFURANTOIN problem was reported by a Consumer or non-health professional from UNITED STATES on Oct 12, 2007. Female patient, 41 years of age, weighting 165.0 lb, was diagnosed with infection prophylaxis and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: chest pain, dyspnoea, fatigue, somnolence. NITROFURANTOIN dosage: unknown. Patient recovered.

Nitrofurantoin Side Effects Report #5502665-X
Consumer or non-health professional from UNITED STATES reported NITROFURANTOIN problem on Oct 15, 2007. Male patient was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: dialysis, hepatic failure, renal failure, weight decreased. NITROFURANTOIN dosage: 100 MG, ORAL; 100 MG, ORAL. During the same period patient was treated with NITROFURANTOIN MACROCRYSTALS. Patient died on 10/01/1994.

Nitrofurantoin Side Effects Report #5450992-7
NITROFURANTOIN problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Aug 28, 2007. Female patient, 49 years of age, was diagnosed with urinary tract infection and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, chest pain, dyspnoea, hypersensitivity, rash. NITROFURANTOIN dosage: 50 MG, ORAL. Patient recovered.

Nitrofurantoin Side Effects Report #5474367-X
Physician from UNITED STATES reported NITROFURANTOIN problem on Sept 28, 2007. Female patient, 49 years of age, was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: autoimmune hepatitis, chronic hepatitis, hepatic fibrosis, liver injury. NITROFURANTOIN dosage: 100 MG BID. During the same period patient was treated with PREDNISONE, IMURAN, SYNTHROID, FOSAMAX, CELEBREX. Patient recovered.

Nitrofurantoin Side Effects Report #5406162-1
NITROFURANTOIN problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 02, 2007. Female patient, 62 years of age, weighting 150.0 lb, was diagnosed with urinary tract infection and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: chills, pyrexia, vomiting. NITROFURANTOIN dosage: unknown. Patient recovered.

Nitrofurantoin Side Effects Report #5412844-8
Consumer or non-health professional from UNITED STATES reported NITROFURANTOIN problem on July 24, 2007. Female patient, 86 years of age, was diagnosed with urinary tract infection and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: activities of daily living impaired, dysphagia, dyspnoea, fall, gastric haemorrhage, joint swelling, mental status changes, oedema peripheral. NITROFURANTOIN dosage: unknown. Patient was hospitalized. Patient recovered.

Nitrofurantoin Side Effects Report #5415200-1
NITROFURANTOIN problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 14, 2007. Female patient, 61 years of age, weighting 120.0 lb, was diagnosed with cystitis and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: lip swelling, oedema peripheral, pruritus. NITROFURANTOIN dosage: unknown. Patient recovered.

Nitrofurantoin Side Effects Report #5420639-4
Consumer or non-health professional from UNITED STATES reported NITROFURANTOIN problem on Aug 01, 2007. Female patient, 77 years of age, was diagnosed with cystitis and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: pneumonia, pulmonary fibrosis. NITROFURANTOIN dosage: 50 MG; DAILY; ORAL. During the same period patient was treated with LIPITOR, ASPIRIN, PAROXETIN, METOPROLOL TARTRATE, CALCIUM. Patient recovered.

Nitrofurantoin Side Effects Report #5424748-5
NITROFURANTOIN problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 10, 2007. Female patient, 38 years of age, was diagnosed with urinary tract infection and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: anosmia, chest pain, disease recurrence, hypertonic bladder, hypoaesthesia, multiple sclerosis, muscle spasms, myoclonus. NITROFURANTOIN dosage: unknown. Patient recovered.

Nitrofurantoin Side Effects Report #5426095-4
Health Professional from UNITED STATES reported NITROFURANTOIN problem on Aug 23, 2007. Female patient, 49 years of age, weighting 252.0 lb, was diagnosed with urinary tract infection and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: blood pressure increased, heart rate increased, pharyngeal oedema, swollen tongue. NITROFURANTOIN dosage: 100MG 4 TIMES A DAY PO. Patient was hospitalized. Patient recovered.

Nitrofurantoin Side Effects Report #5442631-6
NITROFURANTOIN problem was reported by a Health Professional from UNITED STATES on Aug 15, 2007. Male patient, 73 years of age, was diagnosed with onychomycosis and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: hepatotoxicity, pulmonary fibrosis, pulmonary oedema, pulmonary toxicity. NITROFURANTOIN dosage: 50 MG, QD. During the same period patient was treated with FLUCONAZOLE, TERAZOSIN HYDROCHLORIDE, CIMETIDINE RPG, FLUTICASONE PROPIONATE, DIPHENHYDRAMINE, IBUPROFEN, FLUOCINONIDE, CENTRUM. Patient recovered.

Nitrofurantoin Side Effects Report #5379401-3
Consumer or non-health professional from UNITED STATES reported NITROFURANTOIN problem on June 22, 2007. Female patient, 61 years of age, weighting 123.0 lb, was diagnosed with urinary tract infection and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, back injury, chest discomfort, chills, cough, dysgeusia, nausea, pharyngolaryngeal pain, pyrexia. NITROFURANTOIN dosage: 100 MG;TWICE A DAY;ORAL. During the same period patient was treated with PROTONIX, LIPITOR, SYNTHROID. Patient recovered.

Nitrofurantoin Side Effects Report #5387592-3
NITROFURANTOIN problem was reported by a Consumer or non-health professional from UNITED STATES on July 11, 2007. Female patient, 34 years of age, weighting 130.0 lb, was diagnosed with cystitis and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: auricular swelling, hyperhidrosis, hyperventilation, nausea, oedema peripheral, swollen tongue, urticaria, vomiting. NITROFURANTOIN dosage: unknown. Patient was hospitalized. Patient recovered.

Nitrofurantoin Side Effects Report #5391264-9
Consumer or non-health professional from UNITED STATES reported NITROFURANTOIN problem on July 06, 2007. Male patient, 87 years of age, was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: abasia, cardiac failure, heart rate decreased, loss of consciousness. NITROFURANTOIN dosage: 50 MG, EVERY 6 HR, ORAL. During the same period patient was treated with ISOSORBIDE, METAPROTERENOL. Patient was hospitalized. Patient died on 05/22/2007.

Nitrofurantoin Side Effects Report #5398589-1
NITROFURANTOIN problem was reported by a Physician from UNITED STATES on July 13, 2007. Male patient, 68 years of age, weighting 244.9 lb, was diagnosed with cystitis and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: blood glucose increased, coagulopathy, deep vein thrombosis, pancreatic carcinoma, pulmonary embolism. NITROFURANTOIN dosage: 100 MG, BID, ORAL. During the same period patient was treated with METOPROLOL TARTRATE, BENAZEPRIL, BUSPIRONE, ACTOS, EXELON, ZOCOR, BICITRA. Patient was hospitalized. Patient died on 06/07/2007.

Nitrofurantoin Side Effects Report #5379401-3
Consumer or non-health professional from UNITED STATES reported NITROFURANTOIN problem on June 22, 2007. Female patient, 61 years of age, weighting 123.0 lb, was diagnosed with urinary tract infection and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, back injury, chest discomfort, chills, cough, dysgeusia, nausea, pharyngolaryngeal pain, pyrexia. NITROFURANTOIN dosage: 100 MG;TWICE A DAY;ORAL. During the same period patient was treated with PROTONIX, LIPITOR, SYNTHROID. Patient recovered.

Nitrofurantoin Side Effects Report #5387592-3
NITROFURANTOIN problem was reported by a Consumer or non-health professional from UNITED STATES on July 11, 2007. Female patient, 34 years of age, weighting 130.0 lb, was diagnosed with cystitis and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: auricular swelling, hyperhidrosis, hyperventilation, nausea, oedema peripheral, swollen tongue, urticaria, vomiting. NITROFURANTOIN dosage: unknown. Patient was hospitalized. Patient recovered.

Nitrofurantoin Side Effects Report #5391264-9
Consumer or non-health professional from UNITED STATES reported NITROFURANTOIN problem on July 06, 2007. Male patient, 87 years of age, was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: abasia, cardiac failure, heart rate decreased, loss of consciousness. NITROFURANTOIN dosage: 50 MG, EVERY 6 HR, ORAL. During the same period patient was treated with ISOSORBIDE, METAPROTERENOL. Patient was hospitalized. Patient died on 05/22/2007.

Nitrofurantoin Side Effects Report #5398589-1
NITROFURANTOIN problem was reported by a Physician from UNITED STATES on July 13, 2007. Male patient, 68 years of age, weighting 244.9 lb, was diagnosed with cystitis and was treated with NITROFURANTOIN. After drug was administered, patient experienced the following problems/side effects: blood glucose increased, coagulopathy, deep vein thrombosis, pancreatic carcinoma, pulmonary embolism. NITROFURANTOIN dosage: 100 MG, BID, ORAL. During the same period patient was treated with METOPROLOL TARTRATE, BENAZEPRIL, BUSPIRONE, ACTOS, EXELON, ZOCOR, BICITRA. Patient was hospitalized. Patient died on 06/07/2007.


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biliary cirrhosis, hepatotoxicity, pulmonary toxicity, transaminases increased, hepatic cirrhosis, hepatotoxicity, interstitial lung disease, lung disorder, pneumothorax, pulmonary fibrosis, pulmonary toxicity, respiratory disorder, respiratory distress, , was diagnosed with prophylaxis urinary tract infection and was diagnosed with neurogenic bladder, prophylaxis urinary tract infection and