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From simple mix-ups to fatal overdoses, medication mistakes happen, on average, once a day to every hospital patient, a new report says. Nationwide, at least 1.5 million people annually are harmed from drug errors, more than half of them in nursing homes.
Many Unfavorable Drug Studies Aren’t Published. Nearly a third of antidepressant drug studies are never published in the medical literature, and nearly all of those happen to show that the drug being tests failed to work.
Only Drugs That are Safe Should be put on the Market. Drug developers are just beginning to come to grips with recent FDA oversight reforms and how they will affect drug safety. But, it appears that industry and consumer advocates are not together on how well the overhaul will be able to prevent future drug safety scandals.

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Review Optimark Safety Reports submitted to FDA

Total Optimark reports: 26.
Optimark FDA safety alerts: 2006 2007 .
Reported deaths: 2    Reported hospitalizations: 6.
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FDA Reported Optimark Side Effects: nephrogenic fibrosing dermopathy, nephrogenic systemic fibrosis, dizziness, urticaria, headache, pain in extremity, arthralgia, asthenia, peritoneal dialysis, vertigo, syncope.
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Optimark Side Effects Report #5201366-5
Health Professional from UNITED STATES reported OPTIMARK problem on Dec 21, 2006. Female patient, 27 years of age, was diagnosed with nuclear magnetic resonance imaging brain and was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: anaphylactic reaction, respiratory distress. OPTIMARK dosage: 13 ML, SINGLE, INTRAVENOUS. Patient was hospitalized. Patient recovered.

Optimark Side Effects Report #5253387-4
OPTIMARK problem was reported by a Health Professional from UNITED STATES on Feb 12, 2007. Female patient, 59 years of age, weighting 170.0 lb, was diagnosed with nuclear magnetic resonance imaging and was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: dyspnoea, erythema, local swelling, pharyngeal oedema, swelling face, urticaria. OPTIMARK dosage: 15 ML, SINGLE, INTRAVENOUS. Patient recovered.

Optimark Side Effects Report #5320330-9
Health Professional from UNITED STATES reported OPTIMARK problem on Nov 29, 2006. Male patient, weighting 175.0 lb, was diagnosed with nuclear magnetic resonance imaging brain and was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: dizziness, syncope, vertigo. OPTIMARK dosage: 16 ML, SINGLE. Patient recovered.

Optimark Side Effects Report #5320334-6
OPTIMARK problem was reported by a Health Professional from UNITED STATES on Nov 29, 2006. Female patient, 40 years of age, weighting 170.0 lb, was diagnosed with nuclear magnetic resonance imaging brain and was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: dizziness, syncope, vertigo. OPTIMARK dosage: 16 ML, SINGLE, INTRAVENOUS. Patient recovered.

Optimark Side Effects Report #5283681-2
Consumer or non-health professional from UNITED STATES reported OPTIMARK problem on Mar 14, 2007. Male patient, 71 years of age, was diagnosed with nuclear magnetic resonance imaging and was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: nephrogenic fibrosing dermopathy. OPTIMARK dosage: unknown. Patient recovered.

Optimark Side Effects Report #5286028-0
OPTIMARK problem was reported by a Physician from UNITED STATES on Mar 16, 2007. Male patient was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: nephrogenic fibrosing dermopathy. OPTIMARK dosage: unknown. During the same period patient was treated with OMNISCAN. Patient recovered.

Optimark Side Effects Report #5294368-4
Consumer or non-health professional from UNITED STATES reported OPTIMARK problem on Apr 09, 2007. Female patient, 34 years of age, weighting 121.0 lb, was diagnosed with nuclear magnetic resonance imaging and was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: alopecia, back pain, fatigue, madarosis, muscular weakness, rash pustular. OPTIMARK dosage: unknown. Patient recovered.

Optimark Side Effects Report #5298535-5
OPTIMARK problem was reported by a Consumer or non-health professional from UNITED STATES on Mar 27, 2007. Male patient, 71 years of age, was diagnosed with nuclear magnetic resonance imaging and was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: nephrogenic fibrosing dermopathy. OPTIMARK dosage: unknown. Patient recovered.

Optimark Side Effects Report #5316349-4
Physician from UNITED STATES reported OPTIMARK problem on Apr 13, 2007. Female patient, 55 years of age, was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: haemodialysis, nephrogenic fibrosing dermopathy. OPTIMARK dosage: unknown. During the same period patient was treated with OPTIMARK IN GLASS VIALS, OPTIMARK IN GLASS VIALS, LEXAPRO, QUININE SULPHATE, AVAPRO, SINGULAIR, FOLATE, PERCOCET. Patient recovered.

Optimark Side Effects Report #5316350-0
OPTIMARK problem was reported by a Physician from UNITED STATES on Apr 13, 2007. Male patient, 62 years of age, was diagnosed with angiogram, nuclear magnetic resonance imaging and was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: arterial stenosis, nephrogenic fibrosing dermopathy, osteomyelitis, peritoneal dialysis. OPTIMARK dosage: unknown. During the same period patient was treated with OPTIMARK IN GLASS VIALS, OPTIMARK IN GLASS VIALS, OPTIMARK IN GLASS VIALS. Patient recovered.

Optimark Side Effects Report #5376318-5
Pharmacist from UNITED STATES reported OPTIMARK problem on June 27, 2007. Female patient, 17 years of age, weighting 133.6 lb, was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: nausea, urticaria. OPTIMARK dosage: 16 ML/ONCE/ANTECUBITAL. Patient recovered.

Optimark Side Effects Report #5060666-2
OPTIMARK problem was reported by a Health Professional from UNITED STATES on July 19, 2006. Male patient, 69 years of age, weighting 240.0 lb, was diagnosed with coronary artery disease, ventricular dysfunction and was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: postoperative thoracic procedure complication, postoperative wound infection, wound infection staphylococcal. OPTIMARK dosage: unknown. During the same period patient was treated with ECOTRIN, LOPRESSOR, ZOFRAN, DEMADEX, ROBITUSSIN DM, PERCOCET, LEVAQUIN. Patient was hospitalized. Patient recovered.

Optimark Side Effects Report #5061023-5
Health Professional from UNITED STATES reported OPTIMARK problem on July 19, 2006. Female patient, 53 years of age, weighting 110.0 lb, was diagnosed with coronary artery disease, ventricular dysfunction and was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: asthenia, blood glucose decreased, depressed level of consciousness, hyperhidrosis. OPTIMARK dosage: unknown. During the same period patient was treated with ASPIRIN, ATENOLOL, ATORVASTATIN CALCIUM, CLOPIDOGREL, ZETIA, HYDROCORTISONE. Patient was hospitalized. Patient recovered.

Optimark Side Effects Report #5093648-5
OPTIMARK problem was reported by a Physician from UNITED STATES on Aug 15, 2006. Female patient, 55 years of age, was diagnosed with nuclear magnetic resonance imaging and was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: nephrogenic fibrosing dermopathy. OPTIMARK dosage: unknown. During the same period patient was treated with LEXAPRO, QUININE SULPHATE, BICARBONATE IN PLASTIC CONTAINER, BENADRYL. Patient recovered.

Optimark Side Effects Report #5093649-7
Physician from UNITED STATES reported OPTIMARK problem on Aug 15, 2006. Male patient, 67 years of age, was diagnosed with nuclear magnetic resonance imaging and was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: nephrogenic fibrosing dermopathy, peritoneal dialysis. OPTIMARK dosage: unknown. Patient recovered.

Optimark Side Effects Report #5117145-3
OPTIMARK problem was reported by a Health Professional from UNITED STATES on Sept 27, 2006. Female patient, 55 years of age, weighting 222.7 lb, was diagnosed with myocardial infarction and was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: arthralgia, nephrogenic fibrosing dermopathy, pain in extremity, post procedural complication. OPTIMARK dosage: 32 ML IV. Patient recovered.

Optimark Side Effects Report #5125801-6
Health Professional from UNITED STATES reported OPTIMARK problem on Oct 10, 2006. Female patient, 55 years of age, weighting 222.4 lb, was diagnosed with chest pain and was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: arthralgia, asthenia, contrast media reaction, oedema peripheral, pain in extremity, rash erythematous, skin warm. OPTIMARK dosage: unknown. During the same period patient was treated with MRI CARDIAC OPTIMARK CONTRAST. Patient recovered.

Optimark Side Effects Report #5166387-X
OPTIMARK problem was reported by a Health Professional from UNITED STATES on Nov 17, 2006. Female patient, 50 years of age, weighting 194.0 lb, was diagnosed with nuclear magnetic resonance imaging and was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: abdominal discomfort, bowel movement irregularity, convulsion, dizziness, foaming at mouth, headache, ocular hyperaemia, vomiting. OPTIMARK dosage: 20 ML, SINGLE, INTRAVENOUS. During the same period patient was treated with GLUCOPHAGE. Patient recovered.

Optimark Side Effects Report #5390885-7
Physician from UNITED STATES reported OPTIMARK problem on June 29, 2007. Male patient, 14 years of age, was diagnosed with nuclear magnetic resonance imaging brain and was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: bradycardia, cachexia, calcinosis, cardiac arrest, cardiac failure, cardiomegaly, continuous haemodiafiltration, diaphragmatic disorder, discomfort. OPTIMARK dosage: 9 ML, SINGLE. During the same period patient was treated with PROHANCE, OMNISCAN, MAGNEVIST, VINCRISTINE, DACTINOMYCIN, CYCLOPHOSPHAMIDE, IFOSFAMIDE. Patient was hospitalized and became disabled. Patient died.

Optimark Side Effects Report #5410912-8
OPTIMARK problem was reported by a Consumer or non-health professional from UNITED STATES on July 30, 2007. Female patient was diagnosed with nuclear magnetic resonance imaging and was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: nephrogenic systemic fibrosis. OPTIMARK dosage: unknown. Patient recovered.

Optimark Side Effects Report #5417478-7
Health Professional from UNITED STATES reported OPTIMARK problem on Aug 10, 2007. Female patient was diagnosed with nuclear magnetic resonance imaging brain and was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: nephrogenic systemic fibrosis. OPTIMARK dosage: 9 ML, SINGLE. During the same period patient was treated with PROHANCE, OMNISCAN, MAGNEVIST, VINCRISTINE, ACTINOMYCIN D, CYCLOPHOSPHAMIDE, IFOSFAMIDE. Patient was hospitalized and became disabled. Patient died.

Optimark Side Effects Report #5423874-4
OPTIMARK problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 13, 2007. Female patient was diagnosed with nuclear magnetic resonance imaging and was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: nephrogenic systemic fibrosis. OPTIMARK dosage: unknown. Patient recovered.

Optimark Side Effects Report #5427032-9
Physician from UNITED STATES reported OPTIMARK problem on Aug 24, 2007. Female patient, 42 years of age, weighting 132.3 lb, was diagnosed with dizziness, headache and was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: dizziness, headache, joint stiffness, nephrogenic systemic fibrosis. OPTIMARK dosage: unknown. Patient recovered.

Optimark Side Effects Report #5429109-0
OPTIMARK problem was reported by a Health Professional from BRAZIL on Aug 02, 2007. Female patient was diagnosed with nuclear magnetic resonance imaging brain and was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: face oedema, laryngeal oedema, urticaria. OPTIMARK dosage: 10 ML, SINGLE. Patient was hospitalized. Patient recovered.

Optimark Side Effects Report #5447410-1
Consumer or non-health professional from UNITED STATES reported OPTIMARK problem on Aug 28, 2007. Female patient was diagnosed with nuclear magnetic resonance imaging and was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: nephrogenic systemic fibrosis. OPTIMARK dosage: unknown. Patient recovered.

Optimark Side Effects Report #5447786-5
OPTIMARK problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 28, 2007. Female patient was diagnosed with nuclear magnetic resonance imaging and was treated with OPTIMARK. After drug was administered, patient experienced the following problems/side effects: nephrogenic systemic fibrosis. OPTIMARK dosage: unknown. Patient recovered.


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anaphylactic reaction, respiratory distress dyspnoea, erythema, local swelling, pharyngeal oedema, swelling face, urticaria, was diagnosed with nuclear magnetic resonance imaging brain and was diagnosed with nuclear magnetic resonance imaging and