PANHEMATIN Side Effects

5672742-1 | Headache, Serum Ferritin Increased
on Feb 21, 2008 Female patient from UNITED STATES , 38 years of age, weighting 200.0 lb, was diagnosed with porphyria acute and was treated with Panhematin (View Usage). Patient experienced the following unwanted or unexpected effects: headache (What is headache?), serum ferritin increased. Panhematin dosage: 301 Mg; X1; Iv. During the same period patient was treated with FOSAMAX (View Fosamax Review and Fosamax Label ), LUPRON (View Lupron Review and Lupron Label ), MULTI VITAMIN (View Multi-vitamin Review and Multi-vitamin Label ), CALCIUM PLUS VITAMIN D (View Calcium Plus Vitamin D Review and Calcium Plus Vitamin D Label ), MAGNESIUM (View Magnesium Review and Magnesium Label ).

5243757-2 | Condition Aggravated, Hyperaesthesia, Movement Disorder, Neuropathy Peripheral, Phlebitis, Porphyria, Sensory Loss, Vein Disorder
Patient was taking Panhematin (View Usage). Patient had the following side effects: condition aggravated, hyperaesthesia, movement disorder (What is movement disorder?), neuropathy peripheral, phlebitis, porphyria, sensory loss, vein disorder on Jan 30, 2007 from UNITED STATES Additional patient health information: Female patient , 40 years of age, weighting 140.0 lb, was diagnosed with porphyria and. Panhematin dosage: 1x Iv. During the same period patient was treated with TPN (View Tpn Review and Tpn Label ), OXYCONTIN (View Oxycontin Review and Oxycontin Label ), DILAUDID (View Dilaudid Review and Dilaudid Label ), FENTANYL TRANSDERMAL SYSTEM (View Fentanyl Transdermal System Review and Fentanyl Transdermal System Label ).

5176252-X | Free Haemoglobin Present, Haemolysis, Red Blood Cells Urine
Adverse event was reported on Nov 08, 2006 by a Female patient taking Panhematin (View Usage) (Dosage: Iv) was diagnosed with porphyria and. Location: UNITED STATES , 27 years of age, After Panhematin was administered, patient had the following side effects: free haemoglobin present, haemolysis, red blood cells urine.

5110530-5 | Anxiety, Body Temperature Decreased, Diarrhoea, Formication, Nausea
on Sep 01, 2006 Female patient from UNITED STATES , 45 years of age, was diagnosed with porphyria and was treated with Panhematin (View Usage). Patient experienced the following unwanted or unexpected effects: anxiety (What is anxiety?), body temperature decreased, diarrhoea, formication, nausea (What is nausea?). Panhematin dosage: Prn; Iv. During the same period patient was treated with MORPHINE (View Morphine Review and Morphine Label ), PROZAC (View Prozac Review and Prozac Label ), PRILOSEC (View Prilosec Review and Prilosec Label ), COMPAZINE (View Compazine Review and Compazine Label ), IRON (View Iron Review and Iron Label ), LORAZEPAM (View Lorazepam Review and Lorazepam Label ).


5097659-5 | Deep Vein Thrombosis, Extravasation, Injection Site Phlebitis
on Aug 17, 2006 Female patient from UNITED STATES , 51 years of age, weighting 216.1 lb, was diagnosed with porphyria and was treated with Panhematin (View Usage). Patient had the following side effects: deep vein thrombosis (What is deep vein thrombosis?), extravasation, injection site phlebitis. Panhematin dosage: 313 Mg; 1x; Iv. During the same period patient was treated with DEXTROSE (View Dextrose Review and Dextrose Label ), TOPROL XL (View Toprol-xl Review and Toprol-xl Label ), EFFEXOR (View Effexor Review and Effexor Label ), CLARITIN (View Claritin Review and Claritin Label ), DIAZIDE (View Diazide Review and Diazide Label ), TRICOR (View Tricor Review and Tricor Label ), NEXIUM (View Nexium Review and Nexium Label ). Patient was hospitalized.

5080533-8 | Haemosiderosis, Immune System Disorder
Patient was taking Panhematin (View Usage). After Panhematin was administered, patient had the following side effects: haemosiderosis, immune system disorder on Aug 01, 2006 from UNITED STATES Additional patient health information: Female patient , 44 years of age, weighting 120.0 lb, was diagnosed with porphyria acute, artificial menopause and. Panhematin dosage: 313 Mg; Q24x5-10 Days Prn; Iv. During the same period patient was treated with LUPRON (Qd; Inj) (View Lupron Review and Lupron Label ), PREMARIN (View Premarin Review and Premarin Label ), METHADONE HCL (View Methadone Hcl Review and Methadone Hcl Label ), ZANTAC (View Zantac Review and Zantac Label ), MORPHINE (View Morphine Review and Morphine Label ), PHENERGAN HCL (View Phenergan Hcl Review and Phenergan Hcl Label ), FOSAMAX (View Fosamax Review and Fosamax Label ).

5041418-6 | Anaphylactic Reaction
Adverse event was reported on Jun 05, 2006 by a Female patient taking Panhematin (View Usage) (Dosage: 210 Mg; 1x; I V) was diagnosed with porphyria acute and. Location: UNITED STATES , 35 years of age, weighting 180.0 lb, Patient experienced the following unwanted or unexpected effects: anaphylactic reaction. During the same period patient was treated with DARVOCET (View Darvocet Review and Darvocet Label ), ALBUMIN (HUMAN) (View Albumin (human) Review and Albumin (human) Label ).

5041416-2 | Anaphylactic Reaction, Infusion Related Reaction
on Jun 05, 2006 Female patient from UNITED STATES , 35 years of age, weighting 180.0 lb, was diagnosed with porphyria acute and was treated with Panhematin (View Usage). Patient had the following side effects: anaphylactic reaction, infusion related reaction. Panhematin dosage: 210 Mg; 1x; Iv. During the same period patient was treated with DARVOCET (View Darvocet Review and Darvocet Label ), ALBUMIN (HUMAN) (View Albumin (human) Review and Albumin (human) Label ).

4989916-5 | Blood Iron Increased, Osteoporosis
on Apr 11, 2006 Female patient from UNITED STATES , 44 years of age, weighting 120.0 lb, was diagnosed with porphyria acute and was treated with Panhematin (View Usage). After Panhematin was administered, patient had the following side effects: blood iron increased, osteoporosis (What is osteoporosis?). Panhematin dosage: 313 Mg; Q24x5-10days Prn; Iv. During the same period patient was treated with ESTROGENS (View Estrogens Review and Estrogens Label ), MORPHINE (View Morphine Review and Morphine Label ), PHENERGAN HCL (View Phenergan Hcl Review and Phenergan Hcl Label ), METHADONE HCL (View Methadone Hcl Review and Methadone Hcl Label ).

4976829-8 | Coagulopathy, Transient Ischaemic Attack
Patient was taking Panhematin (View Usage). Patient experienced the following unwanted or unexpected effects: coagulopathy, transient ischaemic attack on Mar 28, 2006 from UNITED STATES Additional patient health information: Female patient , 50 years of age, was diagnosed with porphyria acute and. Panhematin dosage: .

4965988-9 | Abdominal Distension, Abdominal Pain Upper, Abdominal Tenderness, Arthralgia, Asthma, Blood Pressure Increased, Condition Aggravated, Constipation, Dyspnoea
Adverse event was reported on Mar 17, 2006 by a Female patient taking Panhematin (View Usage) (Dosage: 313 Mg; Qd; Iv) was diagnosed with porphyria acute and. Location: UNITED STATES , 57 years of age, weighting 155.0 lb, Patient had the following side effects: abdominal distension, abdominal pain upper, abdominal tenderness, arthralgia, asthma (What is asthma?), blood pressure increased, condition aggravated, constipation (What is constipation?), dyspnoea. During the same period patient was treated with MORPHINE (View Morphine Review and Morphine Label ), MS CONTIN (View Ms Contin Review and Ms Contin Label ), LORAZEPAM (View Lorazepam Review and Lorazepam Label ), .................... (View .................... Review and .................... Label ), ..................... (View ..................... Review and ..................... Label ), COLACE (View Colace Review and Colace Label ). Patient was hospitalized.

4780753-3 | Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Bladder Disorder, Disorientation, Headache, Muscular Weakness, Platelet Count Decreased
on Sep 12, 2005 Female patient from UNITED STATES , 45 years of age, weighting 108.0 lb, was diagnosed with porphyria and was treated with Panhematin (View Usage). After Panhematin was administered, patient had the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, bladder disorder, disorientation, headache (What is headache?), muscular weakness, platelet count decreased. Panhematin dosage: . During the same period patient was treated with HYDROCORTISONE (View Hydrocortisone Review and Hydrocortisone Label ), PERCOCET (View Percocet Review and Percocet Label ), CYMBALTA (View Cymbalta Review and Cymbalta Label ), LORAZEPAM (View Lorazepam Review and Lorazepam Label ). Patient was hospitalized.

4771668-5 | Blood Pressure Fluctuation, Body Temperature Increased, C-reactive Protein Increased, Catheter Related Complication, Catheter Site Erythema, Catheter Site Haemorrhage, Catheter Site Infection, Catheter Site Pain, Catheter Site Related Reaction
on Aug 25, 2005 Male patient from UNITED STATES , 32 years of age, weighting 226.0 lb, was diagnosed with porphyria and was treated with Panhematin (View Usage). Patient experienced the following unwanted or unexpected effects: blood pressure fluctuation, body temperature increased, c-reactive protein increased, catheter related complication, catheter site erythema, catheter site haemorrhage, catheter site infection, catheter site pain, catheter site related reaction. Panhematin dosage: 312 Mg; Qd; Iv. During the same period patient was treated with LEXAPRO (View Lexapro Review and Lexapro Label ), ALLEGRA (View Allegra Review and Allegra Label ), LORTAB (View Lortab Review and Lortab Label ), CIMETIDINE (View Cimetidine Review and Cimetidine Label ), COMPAZINE (View Compazine Review and Compazine Label ), CLARINEX (View Clarinex Review and Clarinex Label ), ATIVAN (View Ativan Review and Ativan Label ), ELAVIL (View Elavil Review and Elavil Label ).

4577318-5 | Fatigue, Infusion Related Reaction, Pain, Stenotrophomonas Sepsis
Patient was taking Panhematin (View Usage). Patient had the following side effects: fatigue, infusion related reaction, pain (What is pain?), stenotrophomonas sepsis on Jan 21, 2005 from Additional patient health information: Female patient , 51 years of age, weighting 130.0 lb, was diagnosed with porphyria acute and. Panhematin dosage: 40 Mg; Qd; Iv. During the same period patient was treated with ALBUMIN (HUMAN) (5 Ml Iv) (View Albumin (human) Review and Albumin (human) Label ), FOSAMAX (View Fosamax Review and Fosamax Label ), ALDACTONE (View Aldactone Review and Aldactone Label ), KYTRIL (View Kytril Review and Kytril Label ), MAXALT (View Maxalt Review and Maxalt Label ), AMBIEN (View Ambien Review and Ambien Label ). Patient was hospitalized.

4577313-6 | Disseminated Intravascular Coagulation, Hypotension, Infusion Related Reaction, Stenotrophomonas Sepsis
Adverse event was reported on Jan 21, 2005 by a Female patient taking Panhematin (View Usage) (Dosage: 150 Mg, Bid; Iv) was diagnosed with porphyria acute and. Location: , 50 years of age, weighting 145.0 lb, After Panhematin was administered, patient had the following side effects: disseminated intravascular coagulation, hypotension, infusion related reaction, stenotrophomonas sepsis. During the same period patient was treated with ALBUMIN (HUMAN) (5 Ml; Iv) (View Albumin (human) Review and Albumin (human) Label ), KYTRIL (View Kytril Review and Kytril Label ), TENEX (View Tenex Review and Tenex Label ). Patient was hospitalized.

4577312-4 | Culture Urine Positive, Infusion Related Reaction, Staphylococcal Sepsis
on Jan 21, 2005 Female patient from , 20 years of age, weighting 146.0 lb, was diagnosed with porphyria acute and was treated with Panhematin (View Usage). Patient experienced the following unwanted or unexpected effects: culture urine positive, infusion related reaction, staphylococcal sepsis. Panhematin dosage: 200 Mg; Tiw. During the same period patient was treated with ALBUMIN (HUMAN) (Iv) (View Albumin (human) Review and Albumin (human) Label ), DEXTROSE (View Dextrose Review and Dextrose Label ), ZOFRAN (View Zofran Review and Zofran Label ), DIPHENHYDRAMINE HCL (View Diphenhydramine Hcl Review and Diphenhydramine Hcl Label ), PROTONIX (View Protonix Review and Protonix Label ), FULVITE (View Fulvite Review and Fulvite Label ). Patient was hospitalized.